Compounds > nordazepam

nordazepam and phenobarbital

nordazepam has been researched along with phenobarbital in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (33.33)	18.7374
1990's	4 (33.33)	18.2507
2000's	4 (33.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Caron, G; Ermondi, G	1
Lombardo, F; Obach, RS; Waters, NJ	1
Helmsing, PJ; van der Woude, J; van Eupen, OM	1
Bruce, I; Hooper, WD; Reilly, PE	1
Hooper, WD; Mason, SR; Reilly, PE; Thompson, DA	1
Caccia, S; Conti, I; Tridico, RV	1
Dodrill, CB; Ojemann, LM; Temkin, NR; Troupin, AS; Wilensky, AJ	1
Kuhnz, W; Luck, W; Nau, H; Wegener, S	1
Richter, K; Scherber, A	1
Dyer, KR; Forrester, SD; Jacobson, JD; Wilcke, JR	1
Acikgöz, A; Bader, A; Giri, S; Karim, N; Schmidt-Heck, W	1

Trials

1 trial(s) available for nordazepam and phenobarbital

Article	Year
Clorazepate and phenobarbital as antiepileptic drugs: a double-blind study. Neurology, 1981, Volume: 31, Issue:10 Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Clinical Trials as Topic; Clorazepate Dipotassium; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Nordazepam; Phenobarbital; Phenytoin; Psychological Tests	1981

Other Studies

11 other study(ies) available for nordazepam and phenobarbital

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
A micromethod for simultaneous estimation of blood levels of some commonly used antiepileptic drugs. Clinica chimica acta; international journal of clinical chemistry, 1978, Oct-16, Volume: 89, Issue:2 Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Diazepam; Humans; Microchemistry; Nordazepam; Phenobarbital; Phenytoin	1978
Comparative metabolism of clinically important precursors of N-desmethyldiazepam using phenobarbitone-pretreated rat liver microsomes. Biochemical pharmacology, 1992, Mar-17, Volume: 43, Issue:6 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Diazepam; Hydroxylation; Male; Methylation; Microsomes, Liver; Nordazepam; Phenobarbital; Prazepam; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1992
Cytochrome P450IIIA enzymes in rat liver microsomes: involvement in C3-hydroxylation of diazepam and nordazepam but not N-dealkylation of diazepam and temazepam. Molecular pharmacology, 1990, Volume: 37, Issue:5 Topics: Animals; Anti-Anxiety Agents; Cytochrome P-450 Enzyme System; Diazepam; Female; Hydroxylation; Kinetics; Male; Microsomes, Liver; Nordazepam; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors; Species Specificity; Substrate Specificity; Temazepam	1990
Effect of chronic oral delorazepam on in vitro and in vivo hepatic drug-metabolizing enzyme activities in the rat. Research communications in chemical pathology and pharmacology, 1990, Volume: 67, Issue:1 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cytochrome P-450 Enzyme System; Diazepam; Enzyme Induction; In Vitro Techniques; Liver; Male; Mixed Function Oxygenases; Nordazepam; Phenobarbital; Rats; Rats, Inbred Strains	1990
Serum protein binding of diazepam, desmethyldiazepam, furosemide, indomethacin, warfarin, and phenobarbital in human fetus, mother, and newborn infant. Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4 Topics: Blood Proteins; Diazepam; Fatty Acids, Nonesterified; Female; Fetal Blood; Furosemide; Humans; Indomethacin; Infant, Newborn; Maternal-Fetal Exchange; Nordazepam; Phenobarbital; Pregnancy; Protein Binding; Warfarin	1983
[The distribution of drugs between plasma, brain and cerebrospinal fluid in the human]. Sammlung zwangloser Abhandlungen aus dem Gebiete der Psychiatrie und Neurologie, 1982, Volume: 50 Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Carbamazepine; Diazepam; Humans; Lithium; Nordazepam; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Serum Albumin; Sulfamerazine	1982
Effects of a 44-day administration of phenobarbital on disposition of clorazepate in dogs. American journal of veterinary research, 1993, Volume: 54, Issue:7 Topics: Administration, Oral; Analysis of Variance; Animals; Biotransformation; Clorazepate Dipotassium; Dogs; Drug Administration Schedule; Female; Kinetics; Male; Nordazepam; Phenobarbital; Time Factors	1993
Two compartment model of diazepam biotransformation in an organotypical culture of primary human hepatocytes. Toxicology and applied pharmacology, 2009, Jan-15, Volume: 234, Issue:2 Topics: Anti-Inflammatory Agents; Antithyroid Agents; Biotransformation; Cell Separation; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dexamethasone; Diazepam; Enzyme Induction; Hepatocytes; Humans; Hypnotics and Sedatives; Models, Biological; Models, Statistical; Nordazepam; Organ Culture Techniques; Oxazepam; Phenobarbital; Temazepam	2009