Compounds > norcodeine

norcodeine and morphine-6-glucuronide

norcodeine has been researched along with morphine-6-glucuronide in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avdeef, A; Barrett, DA; Davis, SS; Knaggs, RD; Shaw, PN1
Bellman, K; Knegtel, RM; Settimo, L1
Carroll, FI; Che, T; Huang, XP; Jin, J; Karpiak, J; Kroeze, WK; Lansu, K; Liu, J; McCorvy, JD; Nagase, H; Roth, BL; Shoichet, BK1
Verwey-van Wissen, CP; Vree, TB1
Hanioka, N; Oguri, K; Yoshimura, H1
Geisslinger, G; Hofmann, U; Lötsch, J; Rohrbacher, M; Schmidt, H; Schwab, M; Skarke, C1
Auwaerter, V; Dresen, S; Ferreirós, N; Hentschel, R; Hermanns-Clausen, M; Müller, C; Skopp, G; Thierauf, A; Trittler, R; Weinmann, W1
Frost, J; Helland, A; Nordrum, IS; Slørdal, L1
Brede, WR; Frost, J; Hegstad, S; Løkken, TN; Nordrum, IS; Slørdal, L1
Frost, J; Helland, A; Løkken, TN; Nordrum, IS; Slørdal, L1

Trials

1 trial(s) available for norcodeine and morphine-6-glucuronide

ArticleYear
Evidence for morphine-independent central nervous opioid effects after administration of codeine: contribution of other codeine metabolites.
    Clinical pharmacology and therapeutics, 2006, Volume: 79, Issue:1

    Topics: Adult; Algorithms; Analgesics, Opioid; Area Under Curve; Central Nervous System; Codeine; Cytochrome P-450 CYP2D6; Data Interpretation, Statistical; Dealkylation; Female; Humans; Infusions, Intravenous; Male; Models, Statistical; Morphine; Morphine Derivatives; Pupil

2006

Other Studies

9 other study(ies) available for norcodeine and morphine-6-glucuronide

ArticleYear
Octanol-, chloroform-, and propylene glycol dipelargonat-water partitioning of morphine-6-glucuronide and other related opiates.
    Journal of medicinal chemistry, 1996, Oct-25, Volume: 39, Issue:22

    Topics: Biological Transport; Chemical Phenomena; Chemistry, Physical; Chloroform; Hydrogen-Ion Concentration; Morphine Derivatives; Narcotics; Octanols; Potentiometry; Solutions; Solvents

1996
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
In silico design of novel probes for the atypical opioid receptor MRGPRX2.
    Nature chemical biology, 2017, Volume: 13, Issue:5

    Topics: Calcium; Cell Degranulation; Cell Line; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Humans; Ligands; Mast Cells; Molecular Docking Simulation; Molecular Probes; Molecular Structure; Nerve Tissue Proteins; Pyrazoles; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Structure-Activity Relationship

2017
Pharmacokinetics and metabolism of codeine in humans.
    Biopharmaceutics & drug disposition, 1992, Volume: 13, Issue:6

    Topics: Adult; Codeine; Female; Half-Life; Humans; Male; Middle Aged; Morphine; Morphine Derivatives; Protein Binding

1992
Species differences in metabolism of codeine: urinary excretion of codeine glucuronide, morphine-3-glucuronide and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:7

    Topics: Animals; Chromatography, High Pressure Liquid; Codeine; Guinea Pigs; Male; Mice; Morphine; Morphine Derivatives; Rabbits; Rats; Rats, Inbred Strains; Species Specificity

1990
Fatal and severe codeine intoxication in 3-year-old twins--interpretation of drug and metabolite concentrations.
    International journal of legal medicine, 2009, Volume: 123, Issue:5

    Topics: Antitussive Agents; Brain Chemistry; Brain Edema; Child, Preschool; Chromatography, Liquid; Codeine; Cytochrome P-450 CYP2D6; Delayed-Action Preparations; Drug Overdose; Fatal Outcome; Forensic Toxicology; Genotype; Glucuronides; Humans; Medication Errors; Morphine; Morphine Derivatives; Polymorphism, Genetic; Respiratory Aspiration; Tandem Mass Spectrometry; Tissue Distribution; Twins, Monozygotic

2009
Investigation of morphine and morphine glucuronide levels and cytochrome P450 isoenzyme 2D6 genotype in codeine-related deaths.
    Forensic science international, 2012, Jul-10, Volume: 220, Issue:1-3

    Topics: Adult; Aged; Codeine; Cytochrome P-450 Enzyme System; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Genotype; Humans; Isoenzymes; Male; Middle Aged; Morphine; Morphine Derivatives; Narcotics; Polymerase Chain Reaction

2012
A validated method for simultaneous determination of codeine, codeine-6-glucuronide, norcodeine, morphine, morphine-3-glucuronide and morphine-6-glucuronide in post-mortem blood, vitreous fluid, muscle, fat and brain tissue by LC-MS.
    Journal of analytical toxicology, 2015, Volume: 39, Issue:3

    Topics: Adipose Tissue; Autopsy; Brain; Calibration; Cause of Death; Chromatography, High Pressure Liquid; Codeine; Forensic Toxicology; Humans; Limit of Detection; Mass Spectrometry; Morphine Derivatives; Muscle, Skeletal; Opioid-Related Disorders; Reference Standards; Reproducibility of Results; Solid Phase Extraction; Substance Abuse Detection; Vitreous Body

2015
Post-mortem levels and tissue distribution of codeine, codeine-6-glucuronide, norcodeine, morphine and morphine glucuronides in a series of codeine-related deaths.
    Forensic science international, 2016, Volume: 262

    Topics: Adipose Tissue; Adult; Aged; Brain Chemistry; Chromatography, Liquid; Codeine; Cytochrome P-450 CYP2D6; Female; Forensic Toxicology; Genotype; Humans; Male; Mass Spectrometry; Middle Aged; Morphine; Morphine Derivatives; Muscle, Skeletal; Norway; Postmortem Changes; Solid Phase Extraction; Substance-Related Disorders; Tissue Distribution; Vitreous Body; Young Adult

2016