norcodeine has been researched along with codeine in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (25.00) | 18.7374 |
| 1990's | 13 (32.50) | 18.2507 |
| 2000's | 8 (20.00) | 29.6817 |
| 2010's | 9 (22.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avdeef, A; Barrett, DA; Davis, SS; Knaggs, RD; Shaw, PN | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Carroll, FI; Che, T; Huang, XP; Jin, J; Karpiak, J; Kroeze, WK; Lansu, K; Liu, J; McCorvy, JD; Nagase, H; Roth, BL; Shoichet, BK | 1 |
| Yeh, SY | 1 |
| Brunson, MK; Nash, JF | 1 |
| Verwey-van Wissen, CP; Vree, TB | 1 |
| Koopman-Kimenai, PM; Verwey-van Wissen, CP; Vree, TB | 1 |
| Bochner, F; Chen, ZR; Somogyi, A | 2 |
| Liu, JS; Ning, YM | 1 |
| Hanioka, N; Oguri, K; Yoshimura, H | 1 |
| Ladona, MG; Meyer, UA; Mortimer, O; Persson, K; Rane, A; Spalding, D; Zanger, UM | 1 |
| Lindström, B; Persson, K; Rane, A; Spalding, D; Wahlström, A | 1 |
| Gibson, M; Jefferies, TM; Soper, CJ | 1 |
| Bodd, E; Christophersen, AS; Fongen, U | 1 |
| Kunz, DA; Reddy, GS; Vatvars, A | 1 |
| Bodd, E; Drevon, CA; Kveseth, N; Mørland, J; Olsen, H | 1 |
| Cho, N; Hirobe, M; Takayanagi, I | 1 |
| Säwe, J; Tomson, T; Yue, QY | 1 |
| Barrett, DA; Pawula, M; Shaw, PN | 1 |
| Säwe, J; Svensson, JO; Yue, QY | 1 |
| Caraco, Y; Guengerich, FP; Tateishi, T; Wood, AJ | 1 |
| O'Neal, CL; Poklis, A | 1 |
| Braithwaite, R; George, S; Meadway, C | 2 |
| Bechtel, PR; Bechtel, Y; Berard, M; Haffen, E; Masuyer, C; Paintaud, G | 1 |
| Barnes, AJ; Cone, EJ; Huestis, MA; Joseph, RE; Kim, I; Lafko, D; Moolchan, ET; Oyler, JM; Schepers, R | 1 |
| FRASER, HF; ISBELL, H; VANHORN, GD | 1 |
| Baldwin, D; Barnes, AJ; Cooper, GA; Hand, CW; Huestis, MA; Kacinko, SL; Kim, I; Moolchan, ET; Reid, C; Wilson, L | 1 |
| Geisslinger, G; Hofmann, U; Lötsch, J; Rohrbacher, M; Schmidt, H; Schwab, M; Skarke, C | 1 |
| Augsburger, M; Champod, C; Cherix, D; Giroud, C; Kharbouche, H; Mangin, P; Sporkert, F; Wyss, C | 1 |
| Auwaerter, V; Dresen, S; Ferreirós, N; Hentschel, R; Hermanns-Clausen, M; Müller, C; Skopp, G; Thierauf, A; Trittler, R; Weinmann, W | 1 |
| Black, DL; Caplan, YH; Cawthon, B; Cone, EJ; Heltsley, R; Moser, F; Robert, T; Zichterman, A | 1 |
| Choi, H; Chung, H; Chung, KH; Han, E; Jwa, SH; Kim, E; Lee, S; Oh, SM; Yun, YM | 1 |
| Frost, J; Helland, A; Nordrum, IS; Slørdal, L | 1 |
| Brede, WR; Frost, J; Hegstad, S; Løkken, TN; Nordrum, IS; Slørdal, L | 1 |
| Coluzzi, F; Mattia, C | 1 |
| Belford, M; Manicke, NE | 1 |
| Frost, J; Helland, A; Løkken, TN; Nordrum, IS; Slørdal, L | 1 |
3 review(s) available for norcodeine and codeine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
[Morphinan alkaloids present in mammal].
Topics: Animals; Codeine; Endorphins; Humans; Morphine Derivatives | 1990 |
A look inside the association codeine-paracetamol: clinical pharmacology supports analgesic efficacy.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Codeine; Drug Combinations; Drug Therapy, Combination; Humans; Morphine; Pain; Treatment Outcome | 2015 |
2 trial(s) available for norcodeine and codeine
| Article | Year |
|---|---|
Plasma and oral fluid pharmacokinetics and pharmacodynamics after oral codeine administration.
Topics: Administration, Oral; Adult; Body Fluids; Codeine; Female; Humans; Male; Mouth; Narcotics; Pupil; Specimen Handling; Substance Abuse Detection | 2002 |
Evidence for morphine-independent central nervous opioid effects after administration of codeine: contribution of other codeine metabolites.
Topics: Adult; Algorithms; Analgesics, Opioid; Area Under Curve; Central Nervous System; Codeine; Cytochrome P-450 CYP2D6; Data Interpretation, Statistical; Dealkylation; Female; Humans; Infusions, Intravenous; Male; Models, Statistical; Morphine; Morphine Derivatives; Pupil | 2006 |
35 other study(ies) available for norcodeine and codeine
| Article | Year |
|---|---|
Octanol-, chloroform-, and propylene glycol dipelargonat-water partitioning of morphine-6-glucuronide and other related opiates.
Topics: Biological Transport; Chemical Phenomena; Chemistry, Physical; Chloroform; Hydrogen-Ion Concentration; Morphine Derivatives; Narcotics; Octanols; Potentiometry; Solutions; Solvents | 1996 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
In silico design of novel probes for the atypical opioid receptor MRGPRX2.
Topics: Calcium; Cell Degranulation; Cell Line; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Humans; Ligands; Mast Cells; Molecular Docking Simulation; Molecular Probes; Molecular Structure; Nerve Tissue Proteins; Pyrazoles; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Structure-Activity Relationship | 2017 |
Letter: Question about the formation of norcodeine from morphine in man.
Topics: Codeine; Drug Contamination; Humans; Morphine | 1975 |
Gas-chromatographic measurement of codeine and norcodeine in human plasma.
Topics: Chromatography, Gas; Codeine; Humans; Papaverine | 1975 |
Pharmacokinetics and metabolism of codeine in humans.
Topics: Adult; Codeine; Female; Half-Life; Humans; Male; Middle Aged; Morphine; Morphine Derivatives; Protein Binding | 1992 |
Direct determination of codeine, norcodeine, morphine and normorphine with their corresponding O-glucuronide conjugates by high-performance liquid chromatography with electrochemical detection.
Topics: Chromatography, High Pressure Liquid; Codeine; Electrochemistry; Glucuronates; Humans; Hydrolysis; Morphine; Morphine Derivatives; Reproducibility of Results | 1991 |
Lack of effect of paracetamol on the pharmacokinetics and metabolism of codeine in man.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Codeine; Drug Interactions; Female; Humans; Male; Metabolic Clearance Rate; Morphine; Time Factors | 1991 |
Species differences in metabolism of codeine: urinary excretion of codeine glucuronide, morphine-3-glucuronide and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits.
Topics: Animals; Chromatography, High Pressure Liquid; Codeine; Guinea Pigs; Male; Mice; Morphine; Morphine Derivatives; Rabbits; Rats; Rats, Inbred Strains; Species Specificity | 1990 |
Polymorphic formation of morphine from codeine in poor and extensive metabolizers of dextromethorphan: relationship to the presence of immunoidentified cytochrome P-450IID1.
Topics: Antibodies, Monoclonal; Blotting, Western; Codeine; Cytochrome P-450 Enzyme System; Dextromethorphan; Humans; Levorphanol; Microsomes, Liver; Morphine; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Phenotype; Polymorphism, Genetic | 1990 |
Simultaneous determination of codeine, norcodeine and morphine in biological fluids by high-performance liquid chromatography with fluorescence detection.
Topics: Adult; Chromatography, High Pressure Liquid; Codeine; Humans; Male; Molecular Structure; Morphine; Particle Size; Spectrometry, Fluorescence | 1989 |
Determination of codeine and its metabolites in human blood plasma and in microsomal incubates by high-performance liquid chromatography with ultraviolet detection.
Topics: Chromatography, High Pressure Liquid; Codeine; Glucuronates; Humans; Microsomes, Liver; Morphine | 1989 |
Isolation of codeine and norcodeine from microbial transformation liquors by preparative high-performance liquid chromatography.
Topics: Bacteria; Chromatography, High Pressure Liquid; Codeine; Spectrophotometry, Ultraviolet | 1987 |
Normorphine is the major metabolite of norcodeine in isolated rat hepatocytes.
Topics: Animals; Cells, Cultured; Chromatography, Gas; Chromatography, High Pressure Liquid; Codeine; Liver; Male; Morphine Derivatives; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet | 1986 |
Identification of transformation products arising from bacterial oxidation of codeine by Streptomyces griseus.
Topics: Biotransformation; Chromatography, Gas; Codeine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Streptomyces griseus | 1985 |
Ethanol inhibition of codeine and morphine metabolism in isolated rat hepatocytes.
Topics: Animals; Cells, Cultured; Codeine; Ethanol; Liver; Morphine; Morphine Derivatives; Rats | 1986 |
Effects of epoxidation on the actions of normorphine, norcodeine, N-allylnormorphine(nalorphine) and N-allylnorcodeine on the electrically stimulated guinea pig ileum.
Topics: Animals; Codeine; Electric Stimulation; Epoxy Compounds; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Nalorphine | 1985 |
Carbamazepine and cigarette smoking induce differentially the metabolism of codeine in man.
Topics: Adolescent; Adult; Carbamazepine; Codeine; Drug Synergism; Female; Glucuronates; Humans; Male; Middle Aged; Nicotiana; Plants, Toxic; Smoking | 1994 |
Determination of codeine and its metabolites in microsomal incubates by high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Codeine; Electrochemistry; Microsomes, Liver; Morphine; Rats; Spectrophotometry, Ultraviolet | 1994 |
Determination of codeine and metabolites in plasma and urine using ion-pair high-performance liquid chromatography.
Topics: Calibration; Chromatography, High Pressure Liquid; Codeine; Humans; Morphine; Morphine Derivatives; Substance Abuse Detection | 1995 |
Microsomal codeine N-demethylation: cosegregation with cytochrome P4503A4 activity.
Topics: Aryl Hydrocarbon Hydroxylases; Codeine; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases | 1996 |
The detection of acetylcodeine and 6-acetylmorphine in opiate positive urines.
Topics: Biomarkers; Codeine; Gas Chromatography-Mass Spectrometry; Heroin Dependence; Humans; Morphine; Morphine Derivatives; Narcotics; Reproducibility of Results; Substance Abuse Detection | 1998 |
Opiate concentrations following the ingestion of poppy seed products--evidence for 'the poppy seed defence'.
Topics: Administration, Oral; Adult; Codeine; Food Analysis; Gas Chromatography-Mass Spectrometry; Humans; Male; Morphine; Morphine Derivatives; Narcotics; Papaver; Plants, Medicinal; Seeds; Thebaine | 1998 |
On the assessment of drug metabolism by assays of codeine and its main metabolites.
Topics: Adult; Chromatography, High Pressure Liquid; Codeine; Cytochrome P-450 CYP2D6; Debrisoquin; Dextromethorphan; Female; Glucuronides; Humans; Linear Models; Male; Methylation; Middle Aged; Morphine; Phenotype; Polymorphism, Genetic; Reproducibility of Results; Sensitivity and Specificity | 2000 |
A rapid GC-MS method for the determination of dihydrocodeine, codeine, norcodeine, morphine, normorphine and 6-MAM in urine.
Topics: Adolescent; Adult; Codeine; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Morphine; Morphine Derivatives; Narcotics | 2002 |
Human pharmacology and addiction liability of norcodeine.
Topics: Behavior, Addictive; Codeine; Humans | 1960 |
Performance characteristics of the Cozart RapiScan Oral Fluid Drug Testing System for opiates in comparison to ELISA and GC/MS following controlled codeine administration.
Topics: Analgesics, Opioid; Codeine; Enzyme-Linked Immunosorbent Assay; False Negative Reactions; False Positive Reactions; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Saliva; Sensitivity and Specificity; Substance Abuse Detection | 2004 |
Codeine accumulation and elimination in larvae, pupae, and imago of the blowfly Lucilia sericata and effects on its development.
Topics: Animals; Codeine; Diptera; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Larva; Liver; Morphine; Narcotics; Pupa; Swine | 2008 |
Fatal and severe codeine intoxication in 3-year-old twins--interpretation of drug and metabolite concentrations.
Topics: Antitussive Agents; Brain Chemistry; Brain Edema; Child, Preschool; Chromatography, Liquid; Codeine; Cytochrome P-450 CYP2D6; Delayed-Action Preparations; Drug Overdose; Fatal Outcome; Forensic Toxicology; Genotype; Glucuronides; Humans; Medication Errors; Morphine; Morphine Derivatives; Polymorphism, Genetic; Respiratory Aspiration; Tandem Mass Spectrometry; Tissue Distribution; Twins, Monozygotic | 2009 |
Urine testing for norcodeine, norhydrocodone, and noroxycodone facilitates interpretation and reduces false negatives.
Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; False Negative Reactions; Forensic Toxicology; Humans; Hydrocodone; Medication Adherence; Morphinans; Oxycodone; Oxymorphone; Pain; Tandem Mass Spectrometry | 2010 |
Simultaneous quantification of opiates and effect of pigmentation on its deposition in hair.
Topics: Animals; Codeine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Hair Color; Male; Morphine; Morphine Derivatives; Narcotics; Rats; Rats, Zucker; Solid Phase Extraction; Substance Abuse Detection | 2010 |
Investigation of morphine and morphine glucuronide levels and cytochrome P450 isoenzyme 2D6 genotype in codeine-related deaths.
Topics: Adult; Aged; Codeine; Cytochrome P-450 Enzyme System; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Genotype; Humans; Isoenzymes; Male; Middle Aged; Morphine; Morphine Derivatives; Narcotics; Polymerase Chain Reaction | 2012 |
A validated method for simultaneous determination of codeine, codeine-6-glucuronide, norcodeine, morphine, morphine-3-glucuronide and morphine-6-glucuronide in post-mortem blood, vitreous fluid, muscle, fat and brain tissue by LC-MS.
Topics: Adipose Tissue; Autopsy; Brain; Calibration; Cause of Death; Chromatography, High Pressure Liquid; Codeine; Forensic Toxicology; Humans; Limit of Detection; Mass Spectrometry; Morphine Derivatives; Muscle, Skeletal; Opioid-Related Disorders; Reference Standards; Reproducibility of Results; Solid Phase Extraction; Substance Abuse Detection; Vitreous Body | 2015 |
Separation of opiate isomers using electrospray ionization and paper spray coupled to high-field asymmetric waveform ion mobility spectrometry.
Topics: Aerosols; Analgesics, Opioid; Chemistry, Clinical; Codeine; Electrochemical Techniques; Feasibility Studies; Forensic Toxicology; Hydromorphone; Morphine; Paper; Solvents; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2015 |
Post-mortem levels and tissue distribution of codeine, codeine-6-glucuronide, norcodeine, morphine and morphine glucuronides in a series of codeine-related deaths.
Topics: Adipose Tissue; Adult; Aged; Brain Chemistry; Chromatography, Liquid; Codeine; Cytochrome P-450 CYP2D6; Female; Forensic Toxicology; Genotype; Humans; Male; Mass Spectrometry; Middle Aged; Morphine; Morphine Derivatives; Muscle, Skeletal; Norway; Postmortem Changes; Solid Phase Extraction; Substance-Related Disorders; Tissue Distribution; Vitreous Body; Young Adult | 2016 |