Page last updated: 2024-08-22

nootkatone and sesquiterpenes

nootkatone has been researched along with sesquiterpenes in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.54)	18.7374
1990's	0 (0.00)	18.2507
2000's	15 (23.08)	29.6817
2010's	39 (60.00)	24.3611
2020's	10 (15.38)	2.80

Authors

Authors	Studies
Asakawa, Y; Ishida, T; Takemoto, T; Toyota, M	1
Fukuda, K; Guo, LQ; Ohta, T; Tassaneeyakul, W; Yamazoe, Y	1
Chen, F; Henderson, G; Laine, RA; Maistrello, L; Zhu, BC	1
Henderson, G; Laine, RA; Maistrello, L	2
Ishihara, M; Miyazawa, M; Tougo, H	1
Biolatto, A; Cantet, RJ; Güemes, DR; Pensel, NA; Sancho, AM	1
Fei, H; Henderson, G; Ibrahim, SA; Laine, RA; Zhu, BC	1
Berger, RG; Kaspera, R; Krings, U; Nanzad, T	1
Dolan, MC; Karchesy, JJ; Khasawneh, M; Maupin, GO; Montenieri, JA; Panella, NA; Peralta-Cruz, J; Xiong, Y	1
Asakawa, Y; Furusawa, M; Hashimoto, T; Noma, Y	2
Hennon, PE; Huso, M; Karchesy, JJ; Kelsey, RG	1
Berger, RG; Fraatz, MA; Zorn, H	1
Crowe, WE; Henderson, G; Laine, RA; Sauer, AM	1
Dolan, MC; Jordan, RA; Karchesy, JJ; Manning, MC; Piesman, J; Ruffolo, D; Schmidt, JP; Schulze, CJ; Schulze, TL	1
Haramizu, S; Hase, T; Minegishi, Y; Misawa, K; Murase, T	1
Corazza, ML; de Oliveira, D; Esmelindro, MC; Fernandes, IA; Franceschi, E; Frizzo, CD; Oliveira, JV; Treichel, H	1
Crowe, W; Henderson, G; Laine, RA; Sauer, AM; Zhu, BC	1
Beekwilder, J; Bosch, D; Bouwmeester, H; Cankar, K; Sonke, T; van Houwelingen, A	1
Jung, YS; Kim, YS; Kwak, JH; Lee, DU; Lee, SM; Seo, EJ	1
Gliszczyńska, A; Janeczko, T; Świtalska, M; Wawrzeńczyk, C; Wietrzyk, J; Łysek, A	1
Behle, RW; Flor-Weiler, LB; Stafford, KC	1
Dolan, MC; Jordan, RA; Piesman, J; Schulze, TL	1
Karchesy, JJ; Khasawneh, MA; Peralta-Cruz, J; Xiong, Y	1
Chang, KC; Jang, HJ; Kim, HJ; Kim, YM; Kwak, JH; Lee, DU; Lee, JH; Lee, YS; Seo, HG; Tsoyi, K	1
Burke, L; Castell, LM; Haramizu, S; Jones, AM; Ranchordas, M; Stear, S	1
Bernhardt, R; Hutter, MC; Khatri, Y; Ly, TT; Zapp, J	1
Behle, RW; Bharadwaj, A; Flor-Weiler, LB; Stafford, KC	1
Berger, RG; Krings, U; Zelena, K	1
Dolan, MC; Jordan, RA; Schulze, TL	2
Behle, RW; Bharadwaj, A; Stafford, KC	1
Gavira, C; Höfer, R; Lambert, F; Lesot, A; Werck-Reichhart, D; Zucca, J	1
Chen, F; Duan, J; Li, Y; Tan, Y; Wang, S; Xu, P; Zhang, J	1
Handore, KL; Reddy, DS; Seetharamsingh, B	1
Achkar, J; Beekwilder, J; Bosch, D; Bouwmeester, H; Cankar, K; de Jong, RM; Sonke, T; Stoopen, G; van Dijk, AD; van Houwelingen, A	1
Beekwilder, J; Bosch, D; Bouwmeester, H; Cankar, K; de Jong, RM; Goedbloed, M; Renirie, R; Sonke, T; van Houwelingen, A	1
Fasan, R; Kolev, JN; Ravikumar, R; Zaengle, JM	1
Choi, HJ; Jung, YS; Lee, JH	1
Augustin, P; Engleder, M; Kaluzna, I; Leitner, E; Mink, D; Müller, M; Pichler, H; Schürmann, M; Schwab, H; Wriessnegger, T; Zellnig, G	1
Chen, H; Guo, P; Ho, HM; Jaiswal, Y; Liang, Z; Zhao, Z	1
Berger, RG; Krings, U; Omarini, AB; Plagemann, I; Schimanski, S	1
Pompon, D; Truan, G; Urban, P	1
Berger, RG; Leonhardt, RH	1
Bernhardt, R; Litzenburger, M; Ly, TT; Ringle, M; Schifrin, A	1
Baud, O; Filipek, S; Pick, H; Veya, L; Vogel, H; Yuan, S	1
Hassan, K; Kurdi, A; Rajesh, M; Venkataraman, B	1
Groth, G; Rühlmann, A; Urlacher, VB	1
Behrens, C; Berger, RG; Kolwek, J; Krings, U; Linke, D	1
Al-Salam, S; Ali, BH; Beegam, S; Nemmar, A; Yuvaraju, P	1
Al-Salam, S; Ali, BH; Beegam, S; Hamadi, N; Nemmar, A; Yuvaraju, P	1
Bi, K; Fan, K; Jia, Y; Li, T; Wang, M; Wang, Y; Xiao, F; Xu, M; Yan, T	1
Bernhardt, R; Gerber, A; Hartz, P; Milhim, M	1
Chen, J; Chen, M; Liu, Y; Peng, Z; Shi, M; Wen, H; Xu, J; Yuan, Z; Zhang, H	1
Api, AM; Belsito, D; Biserta, S; Botelho, D; Bruze, M; Burton, GA; Buschmann, J; Cancellieri, MA; Dagli, ML; Date, M; Dekant, W; Deodhar, C; Fryer, AD; Gadhia, S; Jones, L; Joshi, K; Lapczynski, A; Lavelle, M; Liebler, DC; Na, M; O'Brien, D; Patel, A; Penning, TM; Ritacco, G; Rodriguez-Ropero, F; Romine, J; Sadekar, N; Salvito, D; Schultz, TW; Siddiqi, F; Sipes, IG; Sullivan, G; Thakkar, Y; Tokura, Y; Tsang, S	1
Baek, SJ; Kim, CT; Lee, J; Lertpatipanpong, P; Park, EY; Ryu, J; Yoo, E	1
Fan, G; Li, X; Pan, SY; Ren, JN; Zhang, LL	2
Deng, Z; Huang, M; Huang, Y; Liu, T; Shen, K; Shi, B; Tian, Z; Wu, L; Xiang, Z; Ye, Z	1
Fan, G; He, J; Li, X; Pan, SY; Ren, JN; Zhang, LL	1
An, Q; Fan, G; Li, X; Pan, SY; Qu, SS; Ren, JN; Zhang, LL	1
Chen, Y; Fan, G; Li, X; Li, ZJ; Zhang, LL	1
Abdeen, A; Abdelkader, A; Abdelrahaman, D; Atwa, AM; Behairy, A; El-Hanafy, AA; El-Mosallamy, SA; Elgameel, D; Fericean, L; Ghamry, HI; Habotta, OA; Hasan, T; Ibrahim, SF; Imbrea, F; Mahdi, MR; Yassin, N	1
Cai, S; Chen, D; Chen, H; Li, S; Liu, P; Ma, L; Wu, T; Zhou, J; Zhu, C	1

Reviews

5 review(s) available for nootkatone and sesquiterpenes

Article	Year
Nootkatone--a biotechnological challenge. Applied microbiology and biotechnology, 2009, Volume: 83, Issue:1 Topics: Bacteria; Biotechnology; Cell Extracts; Flavoring Agents; Fungi; Plants; Polycyclic Sesquiterpenes; Sesquiterpenes	2009
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--Part 27. British journal of sports medicine, 2011, Volume: 45, Issue:15 Topics: Athletic Performance; Dietary Supplements; Fatty Alcohols; Humans; Nitrates; Physical Endurance; Polycyclic Sesquiterpenes; Sesquiterpenes	2011
Nootkatone. Advances in biochemical engineering/biotechnology, 2015, Volume: 148 Topics: Catalysis; Cytochrome P-450 Enzyme System; Drug Delivery Systems; Escherichia coli; Industrial Microbiology; Insecticides; Laccase; Lipoxygenases; Metabolic Engineering; Oxidoreductases; Pleurotus; Polycyclic Sesquiterpenes; Saccharomyces cerevisiae; Sesquiterpenes	2015
RIFM fragrance ingredient safety assessment, nootkatone, CAS Registry Number 4674-50-4. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Jul-15, Volume: 141 Suppl 1 Topics: Humans; Odorants; Perfume; Polycyclic Sesquiterpenes; Registries; Sesquiterpenes; Toxicity Tests	2020
Production, Function, and Applications of the Sesquiterpenes Valencene and Nootkatone: a Comprehensive Review. Journal of agricultural and food chemistry, 2023, Jan-11, Volume: 71, Issue:1 Topics: Animals; Polycyclic Sesquiterpenes; Sesquiterpenes	2023

Other Studies

60 other study(ies) available for nootkatone and sesquiterpenes

Article	Year
Terpenoid biotransformation in mammals. IV Biotransformation of (+)-longifolene, (-)-caryophyllene, (-)-caryophyllene oxide, (-)-cyclocolorenone, (+)-nootkatone, (-)-elemol, (-)-abietic acid and (+)-dehydroabietic acid in rabbits. Xenobiotica; the fate of foreign compounds in biological systems, 1986, Volume: 16, Issue:8 Topics: Abietanes; Animals; Biotransformation; Diterpenes; Phenanthrenes; Polycyclic Sesquiterpenes; Rabbits; Sesquiterpenes	1986
Inhibition selectivity of grapefruit juice components on human cytochromes P450. Archives of biochemistry and biophysics, 2000, Jun-15, Volume: 378, Issue:2 Topics: Aryl Hydrocarbon Hydroxylases; Beverages; Chromatography, High Pressure Liquid; Citrus; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Furocoumarins; Humans; Inhibitory Concentration 50; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Polycyclic Sesquiterpenes; Sesquiterpenes; Substrate Specificity; Time Factors	2000
Nootkatone is a repellent for Formosan subterranean termite (Coptotermes formosanus). Journal of chemical ecology, 2001, Volume: 27, Issue:3 Topics: Animals; Behavior, Animal; Biological Assay; Chromatography, Thin Layer; Feeding Behavior; Gas Chromatography-Mass Spectrometry; Insect Repellents; Isoptera; Plant Roots; Poaceae; Polycyclic Sesquiterpenes; Sesquiterpenes	2001
Efficacy of vetiver oil and nootkatone as soil barriers against Formosan subterranean termite (Isoptera: Rhinotermitidae). Journal of economic entomology, 2001, Volume: 94, Issue:6 Topics: Animals; Eating; Female; Insect Control; Isoptera; Oils, Volatile; Plant Oils; Poaceae; Polycyclic Sesquiterpenes; Population Density; Sesquiterpenes	2001
Inhibition of acetylcholinesterase activity by essential oil from Citrus paradisi. Natural product letters, 2001, Volume: 15, Issue:3 Topics: Acetylcholinesterase; Animals; Cattle; Cholinesterase Inhibitors; Citrus; Coumarins; Dose-Response Relationship, Drug; Erythrocytes; Gas Chromatography-Mass Spectrometry; Inhibitory Concentration 50; Kinetics; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Oils; Plants, Medicinal; Polycyclic Sesquiterpenes; Sesquiterpenes; Spectrophotometry, Infrared; United States	2001
Use of nootkatone as a senescence indicator for Rouge La Toma Cv. grapefruit (Citrus paradisi Macf.). Journal of agricultural and food chemistry, 2002, Aug-14, Volume: 50, Issue:17 Topics: Citrus; Food Preservation; Fruit; Gas Chromatography-Mass Spectrometry; Linear Models; Polycyclic Sesquiterpenes; Sesquiterpenes; Temperature; Time Factors	2002
Comparative effects of vetiver oil, nootkatone and disodium octaborate tetrahydrate on Coptotermes formosanus and its symbiotic fauna. Pest management science, 2003, Volume: 59, Issue:1 Topics: Animals; Borates; Eukaryota; Insect Control; Insecticides; Isoptera; Plant Oils; Polycyclic Sesquiterpenes; Population Dynamics; Sesquiterpenes; Species Specificity; Symbiosis; Wood	2003
Toxicity and behavioral effects of nootkatone, 1,10-dihydronootkatone, and tetrahydronootkatone to the formosan subterranean termite (Isoptera: Rhinotermitidae). Journal of economic entomology, 2004, Volume: 97, Issue:1 Topics: Animals; Behavior, Animal; Insect Repellents; Insecticides; Isoptera; Polycyclic Sesquiterpenes; Sesquiterpenes	2004
Bioconversion of (+)-valencene in submerged cultures of the ascomycete Chaetomium globosum. Applied microbiology and biotechnology, 2005, Volume: 67, Issue:4 Topics: Biotechnology; Chaetomium; Culture Media; Epoxy Compounds; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Polycyclic Sesquiterpenes; Sesquiterpenes	2005
Use of novel compounds for pest control: insecticidal and acaricidal activity of essential oil components from heartwood of Alaska yellow cedar. Journal of medical entomology, 2005, Volume: 42, Issue:3 Topics: Aedes; Animals; Chamaecyparis; Cymenes; Insecticides; Ixodes; Monoterpenes; Oils, Volatile; Plant Oils; Polycyclic Sesquiterpenes; Sesquiterpenes; Siphonaptera; Terpenes; Wood	2005
Biotransformation of citrus aromatics nootkatone and valencene by microorganisms. Chemical & pharmaceutical bulletin, 2005, Volume: 53, Issue:11 Topics: Animals; Biotransformation; Chromatography, Gas; Citrus; Fungi; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Polycyclic Sesquiterpenes; Rabbits; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared	2005
Highly efficient production of nootkatone, the grapefruit aroma from valencene, by biotransformation. Chemical & pharmaceutical bulletin, 2005, Volume: 53, Issue:11 Topics: Biotransformation; Chlorella; Citrus; Fungi; Gas Chromatography-Mass Spectrometry; Kinetics; Odorants; Polycyclic Sesquiterpenes; Sesquiterpenes	2005
Changes in heartwood chemistry of dead yellow-cedar trees that remain standing for 80 years or more in southeast Alaska. Journal of chemical ecology, 2005, Volume: 31, Issue:11 Topics: Acetates; Alaska; Biodegradation, Environmental; Chamaecyparis; Chromatography, Gas; Cymenes; Ecology; Geography; Monoterpenes; Plant Bark; Plant Extracts; Polycyclic Sesquiterpenes; Sesquiterpenes; Species Specificity; Time Factors; Wood	2005
An efficient and economic asymmetric synthesis of (+)-nootkatone, tetrahydronootkatone, and derivatives. Organic letters, 2009, Aug-20, Volume: 11, Issue:16 Topics: Catalysis; Molecular Structure; Polycyclic Sesquiterpenes; Sesquiterpenes; Stereoisomerism	2009
Ability of two natural products, nootkatone and carvacrol, to suppress Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae) in a Lyme disease endemic area of New Jersey. Journal of economic entomology, 2009, Volume: 102, Issue:6 Topics: Acaricides; Animals; Chamaecyparis; Cymenes; Ixodes; Lyme Disease; Monoterpenes; New Jersey; Plant Extracts; Polycyclic Sesquiterpenes; Sesquiterpenes; Tick Control	2009
Nootkatone, a characteristic constituent of grapefruit, stimulates energy metabolism and prevents diet-induced obesity by activating AMPK. American journal of physiology. Endocrinology and metabolism, 2010, Volume: 299, Issue:2 Topics: Adenine Nucleotides; Animals; Anti-Obesity Agents; Blotting, Western; Calorimetry, Indirect; Cells, Cultured; Citrus paradisi; Cyclic AMP-Dependent Protein Kinases; Diet; Energy Metabolism; Enzyme Activation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Obesity; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptors; Physical Endurance; Polycyclic Sesquiterpenes; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sesquiterpenes; Stimulation, Chemical; Swimming	2010
Catalytic oxidation of concentrated orange oil phase by synthetic metallic complexes biomimetic to MMO enzyme. Journal of the science of food and agriculture, 2010, Volume: 90, Issue:9 Topics: Biomimetic Materials; Catalysis; Coordination Complexes; Gas Chromatography-Mass Spectrometry; Hot Temperature; Hydrogen Peroxide; Kinetics; Metalloproteins; Osmolar Concentration; Oxidants; Oxidation-Reduction; Oxygenases; Plant Oils; Polycyclic Sesquiterpenes; Sesquiterpenes	2010
Structural requirements for repellency: norsesquiterpenes and sesquiterpenoid derivatives of nootkatone against the Formosan subterranean termite (Isoptera: Rhinotermitidae). Pest management science, 2010, Volume: 66, Issue:8 Topics: Animals; Insect Repellents; Isoptera; Polycyclic Sesquiterpenes; Sesquiterpenes; Structure-Activity Relationship	2010
A chicory cytochrome P450 mono-oxygenase CYP71AV8 for the oxidation of (+)-valencene. FEBS letters, 2011, Jan-03, Volume: 585, Issue:1 Topics: Biocatalysis; Cichorium intybus; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA, Complementary; Expressed Sequence Tags; Gene Library; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Plant Proteins; Polycyclic Sesquiterpenes; Sequence Analysis, DNA; Sesquiterpenes; Sesquiterpenes, Germacrane; Stereoisomerism; Yeasts	2011
Antiplatelet effects of Cyperus rotundus and its component (+)-nootkatone. Journal of ethnopharmacology, 2011, Apr-26, Volume: 135, Issue:1 Topics: Animals; Arachidonic Acid; Bleeding Time; Collagen; Cyperus; Mice; Mice, Inbred ICR; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Polycyclic Sesquiterpenes; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Thrombin	2011
Microbial transformation of (+)-nootkatone and the antiproliferative activity of its metabolites. Bioorganic & medicinal chemistry, 2011, Apr-01, Volume: 19, Issue:7 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Biotransformation; Cell Growth Processes; Cell Line, Tumor; Fungi; HL-60 Cells; Humans; Lung Neoplasms; Molecular Conformation; Molecular Structure; Polycyclic Sesquiterpenes; Sesquiterpenes; Stereoisomerism	2011
Susceptibility of four tick species, Amblyomma americanum, Dermacentor variabilis, Ixodes scapularis, and Rhipicephalus sanguineus (Acari: Ixodidae), to nootkatone from essential oil of grapefruit. Journal of medical entomology, 2011, Volume: 48, Issue:2 Topics: Acaricides; Animals; Citrus paradisi; Ixodidae; Oils, Volatile; Plant Oils; Polycyclic Sesquiterpenes; Sesquiterpenes	2011
Suppression of host-seeking Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae) nymphs after dual applications of plant-derived acaricides in New Jersey. Journal of economic entomology, 2011, Volume: 104, Issue:2 Topics: Acaricides; Animals; Cymenes; Ixodes; Monoterpenes; New Jersey; Nymph; Plant Extracts; Polycyclic Sesquiterpenes; Sesquiterpenes; Tick Control	2011
Biologically important eremophilane sesquiterpenes from alaska cedar heartwood essential oil and their semi-synthetic derivatives. Molecules (Basel, Switzerland), 2011, Jun-08, Volume: 16, Issue:6 Topics: Alaska; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Oils, Volatile; Polycyclic Sesquiterpenes; Sesquiterpenes	2011
(+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction. Journal of ethnopharmacology, 2011, Oct-11, Volume: 137, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cyperus; Disease Models, Animal; Dose-Response Relationship, Drug; Heme Oxygenase-1; HMGB1 Protein; Macrophages; Membrane Proteins; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Extracts; Plants, Medicinal; Polycyclic Sesquiterpenes; Rhizome; RNA Interference; Sepsis; Sesquiterpenes; Time Factors; Transfection; Up-Regulation	2011
CYP264B1 from Sorangium cellulosum So ce56: a fascinating norisoprenoid and sesquiterpene hydroxylase. Applied microbiology and biotechnology, 2012, Volume: 95, Issue:1 Topics: Biotechnology; Cytochrome P-450 Enzyme System; Kinetics; Mixed Function Oxygenases; Models, Molecular; Myxococcales; Norisoprenoids; Polycyclic Sesquiterpenes; Sesquiterpenes	2012
A formulation to encapsulate nootkatone for tick control. Journal of medical entomology, 2011, Volume: 48, Issue:6 Topics: Animals; Brassica; Ixodes; Lignin; Polycyclic Sesquiterpenes; Sesquiterpenes; Tick Control; Volatilization	2011
Functional expression of a valencene dioxygenase from Pleurotus sapidus in E. coli. Bioresource technology, 2012, Volume: 108 Topics: Chromatography, Liquid; Dioxygenases; Escherichia coli; Gas Chromatography-Mass Spectrometry; Inclusion Bodies; Industrial Microbiology; Mass Spectrometry; Pleurotus; Polycyclic Sesquiterpenes; Sesquiterpenes	2012
Experimental use of two standard tick collection methods to evaluate the relative effectiveness of several plant-derived and synthetic repellents against Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae). Journal of economic entomology, 2011, Volume: 104, Issue:6 Topics: Animals; Bedding and Linens; Carbon Dioxide; Cymenes; Insect Control; Insect Repellents; Ixodes; Ixodidae; Monoterpenes; New Jersey; Nymph; Oils, Volatile; Permethrin; Plant Oils; Polycyclic Sesquiterpenes; Sampling Studies; Sesquiterpenes; Species Specificity; Specimen Handling; Time Factors	2011
Efficacy of plant-derived and synthetic compounds on clothing as repellents against Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae). Journal of medical entomology, 2012, Volume: 49, Issue:1 Topics: Animals; Clothing; Cymenes; Insect Repellents; Ixodidae; Monoterpenes; Permethrin; Plants; Polycyclic Sesquiterpenes; Sesquiterpenes; Tick Control	2012
Efficacy and environmental persistence of nootkatone for the control of the blacklegged tick (Acari: Ixodidae) in residential landscapes. Journal of medical entomology, 2012, Volume: 49, Issue:5 Topics: Animals; Connecticut; Ixodes; Lyme Disease; Metarhizium; Nymph; Pest Control, Biological; Polycyclic Sesquiterpenes; Sesquiterpenes; Tick Control	2012
Challenges and pitfalls of P450-dependent (+)-valencene bioconversion by Saccharomyces cerevisiae. Metabolic engineering, 2013, Volume: 18 Topics: Biotransformation; Cytochrome P-450 Enzyme System; Nicotiana; Plant Proteins; Polycyclic Sesquiterpenes; Saccharomyces cerevisiae; Sesquiterpenes	2013
Anti-diarrheal constituents of Alpinia oxyphylla. Fitoterapia, 2013, Volume: 89 Topics: Alpinia; Animals; Antidiarrheals; Aquaporin 4; Diarrhea; Duodenum; Flavonoids; Fruit; Guaiacol; Mice; Mice, Inbred ICR; Molecular Docking Simulation; Peristalsis; Phytotherapy; Plant Extracts; Polycyclic Sesquiterpenes; Sesquiterpenes; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers	2013
Ready access to functionally embellished cis-hydrindanes and cis-decalins: protecting group-free total syntheses of (±)-Nootkatone and (±)-Noreremophilane. The Journal of organic chemistry, 2013, Aug-16, Volume: 78, Issue:16 Topics: Indans; Molecular Structure; Naphthalenes; Polycyclic Sesquiterpenes; Sesquiterpenes; Stereoisomerism	2013
Valencene synthase from the heartwood of Nootka cypress (Callitropsis nootkatensis) for biotechnological production of valencene. Plant biotechnology journal, 2014, Volume: 12, Issue:2 Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Biotechnology; Cupressaceae; Gene Expression; Kinetics; Molecular Sequence Data; Phylogeny; Polycyclic Sesquiterpenes; Recombinant Proteins; Rhodobacter; Sequence Alignment; Sequence Analysis, DNA; Sesquiterpenes; Terpenes; Wood	2014
Valencene oxidase CYP706M1 from Alaska cedar (Callitropsis nootkatensis). FEBS letters, 2014, Mar-18, Volume: 588, Issue:6 Topics: Cloning, Molecular; Cupressaceae; NADPH-Ferrihemoprotein Reductase; Phylogeny; Plant Proteins; Polycyclic Sesquiterpenes; Saccharomyces cerevisiae; Sesquiterpenes; Substrate Specificity	2014
Enhancing the efficiency and regioselectivity of P450 oxidation catalysts by unnatural amino acid mutagenesis. Chembiochem : a European journal of chemical biology, 2014, May-05, Volume: 15, Issue:7 Topics: Amino Acids; Biocatalysis; Catalytic Domain; Cytochrome P-450 Enzyme System; Hydroxylation; Ibuprofen; Mutagenesis; Oxidation-Reduction; Polycyclic Sesquiterpenes; Recombinant Proteins; Sesquiterpenes; Stereoisomerism; Substrate Specificity	2014
(+)-Nootkatone inhibits tumor necrosis factor α/interferon γ-induced production of chemokines in HaCaT cells. Biochemical and biophysical research communications, 2014, May-02, Volume: 447, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chemokine CCL17; Chemokine CCL22; Dermatitis, Atopic; Humans; Interferon-gamma; MAP Kinase Signaling System; NF-kappa B; Polycyclic Sesquiterpenes; Protein Kinase C; RNA, Messenger; Sesquiterpenes; Th2 Cells; Tumor Necrosis Factor-alpha	2014
Production of the sesquiterpenoid (+)-nootkatone by metabolic engineering of Pichia pastoris. Metabolic engineering, 2014, Volume: 24 Topics: Arabidopsis; Arabidopsis Proteins; Cupressus; Hyoscyamus; Metabolic Engineering; Pichia; Polycyclic Sesquiterpenes; Sesquiterpenes	2014
Tissue-specific metabolite profiling of Cyperus rotundus L. rhizomes and (+)-nootkatone quantitation by laser microdissection, ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry, and gas chromatography-mass spectromet Journal of agricultural and food chemistry, 2014, Jul-23, Volume: 62, Issue:29 Topics: Chromatography, High Pressure Liquid; Cyperus; Gas Chromatography-Mass Spectrometry; Lasers; Mass Spectrometry; Polycyclic Sesquiterpenes; Sesquiterpenes	2014
Crosses between monokaryons of Pleurotus sapidus or Pleurotus florida show an improved biotransformation of (+)-valencene to (+)-nootkatone. Bioresource technology, 2014, Volume: 171 Topics: Biotechnology; Biotransformation; Crosses, Genetic; Genes, Mating Type, Fungal; Linoleic Acid; Lipoxygenase; Pleurotus; Polycyclic Sesquiterpenes; Polysorbates; Sesquiterpenes; Species Specificity; Statistics, Nonparametric	2014
High-throughput functional screening of steroid substrates with wild-type and chimeric P450 enzymes. BioMed research international, 2014, Volume: 2014 Topics: Amino Acid Sequence; Cytochrome P-450 Enzyme System; High-Throughput Screening Assays; Humans; Microsomes; Mifepristone; Models, Molecular; Molecular Sequence Data; Polycyclic Sesquiterpenes; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Sequence Alignment; Sesquiterpenes; Steroids; Substrate Specificity	2014
New Sesquiterpene Oxidations with CYP260A1 and CYP264B1 from Sorangium cellulosum So ce56. Chembiochem : a European journal of chemical biology, 2015, Volume: 16, Issue:18 Topics: Bacterial Proteins; Biocatalysis; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Myxococcales; Oxidation-Reduction; Polycyclic Sesquiterpenes; Sesquiterpenes; Substrate Specificity	2015
Exchanging ligand-binding specificity between a pair of mouse olfactory receptor paralogs reveals odorant recognition principles. Scientific reports, 2015, Oct-09, Volume: 5 Topics: Acyclic Monoterpenes; Animals; Benzaldehydes; Binding Sites; Binding, Competitive; Cell Line; Cyclopentanes; Ligands; Mice; Microfilament Proteins; Molecular Dynamics Simulation; Molecular Structure; Monoterpenes; Mutagenesis, Site-Directed; Odorants; Organic Chemicals; Oxylipins; Polycyclic Sesquiterpenes; Protein Isoforms; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Odorant; Sesquiterpenes; Smell	2015
Nootkatone confers hepatoprotective and anti-fibrotic actions in a murine model of liver fibrosis by suppressing oxidative stress, inflammation, and apoptosis. Journal of biochemical and molecular toxicology, 2018, Volume: 32, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Biomarkers; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; DNA Fragmentation; Hepatitis; Injections, Intraperitoneal; Liver; Liver Cirrhosis; Male; Mice, Inbred C57BL; Nitrosative Stress; Oxidative Stress; Polycyclic Sesquiterpenes; Protective Agents; Sesquiterpenes	2018
Characterization of CYP154F1 from Thermobifida fusca YX and Extension of Its Substrate Spectrum by Site-Directed Mutagenesis. Chembiochem : a European journal of chemical biology, 2018, 03-02, Volume: 19, Issue:5 Topics: Actinobacteria; Acyclic Monoterpenes; Amino Acid Sequence; Catalytic Domain; Cytochrome P-450 Enzyme System; Models, Molecular; Mutagenesis, Site-Directed; Polycyclic Sesquiterpenes; Sequence Alignment; Sesquiterpenes; Stilbenes; Substrate Specificity; Terpenes	2018
Cell-free one-pot conversion of (+)-valencene to (+)-nootkatone by a unique dye-decolorizing peroxidase combined with a laccase from Funalia trogii. Journal of industrial microbiology & biotechnology, 2018, Volume: 45, Issue:2 Topics: Anthraquinones; Basidiomycota; Coloring Agents; Laccase; Oxidation-Reduction; Peroxidase; Polycyclic Sesquiterpenes; Sesquiterpenes	2018
Thrombosis and systemic and cardiac oxidative stress and DNA damage induced by pulmonary exposure to diesel exhaust particles and the effect of nootkatone thereon. American journal of physiology. Heart and circulatory physiology, 2018, 05-01, Volume: 314, Issue:5 Topics: Animals; Antioxidants; Blood Coagulation; Blood Platelets; Disease Models, Animal; DNA Damage; Female; Fibrinolytic Agents; Heme Oxygenase-1; Inhalation Exposure; Intracranial Thrombosis; Lipid Peroxidation; Male; Membrane Proteins; Mice, Inbred BALB C; Myocytes, Cardiac; NF-E2-Related Factor 2; Oxidative Stress; Platelet Aggregation; Polycyclic Sesquiterpenes; Sesquiterpenes; Vehicle Emissions	2018
In Vivo Protective Effects of Nootkatone against Particles-Induced Lung Injury Caused by Diesel Exhaust Is Mediated via the NF-κB Pathway. Nutrients, 2018, Feb-26, Volume: 10, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Bronchoalveolar Lavage Fluid; Caspase 3; Citrus paradisi; Comet Assay; Dinoprost; DNA Damage; Glutathione; Lung; Lung Injury; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; NF-kappa B; Nitric Oxide; Oxidative Stress; Particulate Matter; Polycyclic Sesquiterpenes; Protective Agents; Sesquiterpenes; Tumor Necrosis Factor-alpha; Vehicle Emissions	2018
Nootkatone, a neuroprotective agent from Alpiniae Oxyphyllae Fructus, improves cognitive impairment in lipopolysaccharide-induced mouse model of Alzheimer's disease. International immunopharmacology, 2018, Volume: 62 Topics: Alpinia; Alzheimer Disease; Animals; Behavior, Animal; Brain; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Lipopolysaccharides; Male; Maze Learning; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Polycyclic Sesquiterpenes; Sesquiterpenes	2018
A novel short chain dehydrogenase from Bacillus megaterium for the conversion of the sesquiterpene nootkatol to (+)-nootkatone. Journal of biotechnology, 2019, Aug-10, Volume: 301 Topics: Bacillus megaterium; Bacterial Proteins; Escherichia coli; Metabolic Engineering; Polycyclic Sesquiterpenes; Sesquiterpenes; Short Chain Dehydrogenase-Reductases	2019
Volatile Compounds in Fruit Peels as Novel Biomarkers for the Identification of Four Citrus Species. Molecules (Basel, Switzerland), 2019, Dec-12, Volume: 24, Issue:24 Topics: Citrus; Coumarins; Fruit; Polycyclic Sesquiterpenes; Sesquiterpenes; Volatile Organic Compounds	2019
Anti-proliferative activity of A. Oxyphylla and its bioactive constituent nootkatone in colorectal cancer cells. BMC cancer, 2020, Sep-14, Volume: 20, Issue:1 Topics: Alpinia; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Early Growth Response Protein 1; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; Heme Oxygenase-1; Humans; Plant Extracts; Polycyclic Sesquiterpenes; PPAR gamma; Promoter Regions, Genetic; Sesquiterpenes	2020
Advances on (+)-nootkatone microbial biosynthesis and its related enzymes. Journal of industrial microbiology & biotechnology, 2021, Aug-24, Volume: 48, Issue:7-8 Topics: Cytochrome P-450 Enzyme System; Polycyclic Sesquiterpenes; Saccharomyces cerevisiae; Saccharomycetales; Sesquiterpenes	2021
Coupling cell growth and biochemical pathway induction in Saccharomyces cerevisiae for production of (+)-valencene and its chemical conversion to (+)-nootkatone. Metabolic engineering, 2022, Volume: 72 Topics: Metabolic Engineering; Polycyclic Sesquiterpenes; Saccharomyces cerevisiae; Sesquiterpenes	2022
Genomic and transcriptomic analysis screening key genes for (+)-valencene biotransformation to (+)-nootkatone in Yarrowia lipolytica. Microbiological research, 2022, Volume: 260 Topics: Biotransformation; Cytochrome P-450 Enzyme System; Genomics; Polycyclic Sesquiterpenes; Reproducibility of Results; Sesquiterpenes; Transcriptome; Yarrowia	2022
Differential proteomic analysis of citrus flavor (+)-valencene biotransformation to (+)-nootkatone by Yarrowia lipolytica. International journal of biological macromolecules, 2022, Nov-01, Volume: 220 Topics: Amino Acids; Ammonium Sulfate; Biological Products; Biotransformation; Chromatography, Liquid; Citrus; Cytochrome P-450 Enzyme System; Fatty Acids; Polycyclic Sesquiterpenes; Proteomics; Sesquiterpenes; Tandem Mass Spectrometry; Yarrowia	2022
Isolation, purification, and mass spectrometry identification of the enzyme involved in citrus flavor (+)-valencene biotransformation to (+)-nootkatone by Yarrowia lipolytica. Journal of the science of food and agriculture, 2023, Aug-15, Volume: 103, Issue:10 Topics: Biotransformation; Citrus; Mass Spectrometry; Sesquiterpenes; Yarrowia	2023
Sesquiterpene nootkatone counteracted the melamine-induced neurotoxicity via repressing of oxidative stress, inflammatory, and apoptotic trajectories. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165 Topics: Animals; Antioxidants; HMGB Proteins; NF-kappa B; Oxidative Stress; Rats; Sesquiterpenes; Toll-Like Receptor 4	2023
Green Production of a High-value Mosquito Insecticide of Nootkatone from Seaweed Hydrolysates. Journal of agricultural and food chemistry, 2023, Dec-06, Volume: 71, Issue:48 Topics: DEET; Insect Repellents; Insecticides; Polycyclic Sesquiterpenes; Saccharomyces cerevisiae; Sesquiterpenes; Vegetables	2023