nonivamide has been researched along with capsaicin in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (10.47) | 18.7374 |
| 1990's | 15 (17.44) | 18.2507 |
| 2000's | 18 (20.93) | 29.6817 |
| 2010's | 36 (41.86) | 24.3611 |
| 2020's | 8 (9.30) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, IJ; Liou, SJ; Shen, AY; Yeh, JL | 1 |
| Bevan, S; Campbell, EA; Dray, A; James, IF; Perkins, MN; Reid, DJ; Walpole, CS; Winter, J; Wrigglesworth, R | 1 |
| Bevan, S; Campbell, EA; Dray, A; James, IF; Masdin, KJ; Perkins, MN; Walpole, CS; Winter, J; Wrigglesworth, R | 2 |
| Bevan, S; Bloomfield, G; Breckenridge, R; James, IF; Ritchie, T; Szallasi, A; Walpole, CS; Winter, J; Wrigglesworth, R | 1 |
| Chen, IJ; Yeh, JL | 1 |
| Bennett, T; Gardiner, SM; O'Neill, TP | 1 |
| Ando, R; Fujii, T; Kisara, K; Ohbuchi, Y; Sakurada, S; Sakurada, T; Takahashi, S | 1 |
| Foster, RW; Weston, KM | 1 |
| Durant, PA; Yaksh, TL | 1 |
| Ando, R; Fujii, T; Kawamura, S; Kisara, K; Sakurada, S; Yonezawa, A | 1 |
| Andoh, R; Fujii, T; Kisara, K; Sakurada, S; Sasaki, T; Tanno, K; Yabuta, M; Yamaguchi, K | 1 |
| Andoh, R; Fujii, T; Kisara, K; Sakurada, S; Sakurada, T; Yonezawa, A | 1 |
| Donnerer, J; Lembeck, F; Skofitsch, G | 1 |
| Chen, IJ; Chen, SJ; Lo, YC; Wu, JR; Yang, JM; Yeh, JL | 1 |
| Chen, IJ; Lo, YC; Wang, Y; Yeh, JL | 1 |
| Ando, R; Kawamura, S; Kume, H; Sakurada, T; Yonezawa, A | 1 |
| Aronov, EV; Brand, JG; Bryant, BP; Feigin, AM; Teeter, JH | 1 |
| Bowman, LA; Francis, WR; Kasting, GB; Kinnett, GO | 1 |
| Fang, JY; Huang, YB; Tsai, YH; Wu, PC | 1 |
| Kamata, R; Kobayashi, H; Saito, S; Sato, I; Sugawara, E; Suzuki, T; Tachikawa, E; Tomizawa, N; Wada, S | 1 |
| Fang, JY; Huang, YB; Kuo, CT; Tsai, YH; Wu, PC | 1 |
| Chen, IJ; Lin, YT; Lo, YC; Ma, CR; Wu, BN; Yang, YC; Yeh, JL | 1 |
| Hoffmann, K; Lübbers, DW; Röchling, A; Schulze, L; Struk, PA; Stücker, M | 1 |
| Chen, HY; Fang, CL; Fang, JY; Hong, CT; Lin, TY; Wei, HM | 1 |
| Crouc, DJ; Fatah, AA; Reilly, CA; Yost, GS | 1 |
| Chiu, WT; Fang, JY; Hong, CT; Wang, YY | 1 |
| Fang, JY; Leu, YL; Tsai, YH; Wang, YY | 1 |
| Crouch, DJ; Fatah, AA; Reilly, CA; Yost, GS | 1 |
| Gurunluoglu, R; Huemer, GM; Otto-Schoeller, A; Piza-Katzer, H; Schoeller, T; Wechselberger, G | 1 |
| WATANABA, S; YOKOSAWA, M; YOSHICKA, H | 1 |
| Alekseev, SI; Radzievsky, AA; Szabo, I; Ziskin, MC | 1 |
| Appendino, G; Daddario, N; De Petrocellis, L; Di Marzo, V; Minassi, A; Moriello, AS | 1 |
| Johansen, ME; Reilly, CA; Yost, GS | 1 |
| Fang, JY; Huang, YB; Tsai, YH; Wang, HY | 1 |
| Friedman, M; Han, JS; Kim, JA; Kozukue, E; Kozukue, N; Lee, KR; Lee, SJ; Levin, CE | 1 |
| Harada, N; Okajima, K | 1 |
| Johansen, ME; Lanza, DL; Moos, PJ; Reilly, CA; Sabnis, AS; Thomas, KC; Yost, GS | 1 |
| Huang, YB; Lin, YH; Lu, TM; Tsai, YH; Wang, RJ; Wu, PC | 1 |
| Froschauer, SM; Huemer, GM; Kwasny, O; Pachinger, T; Schoffl, H | 1 |
| Alessandra, I; Appendino, G; Atzeri, A; Deiana, M; Dessì, MA; Melis, MP; Minassi, A; Rosa, A | 1 |
| Avlonitis, N; Borgström, EL; Brown, CT; Carr, JL; Conway, SJ; Fayuk, D; Giniatullin, R; Khiroug, L; McDougall, C; Niittykoski, M; Stanton-Humphreys, MN; Surin, A; Van Ryssen, MP | 1 |
| Hawelek, L; Ngai, KL; Paluch, M; Sawicki, W; Wojnarowska, Z | 1 |
| Deering-Rice, CE; Dull, RO; Lee, J; Reilly, CA; Roberts, JK; Romero, EG; Thomas, KC; Yost, GS | 1 |
| Choi, Y; Choo, HW; Kim, MG; Ryu, JK; Shin, BS; Shin, SW; Yoo, SD | 1 |
| Daniels, R; Lunter, DJ | 1 |
| Chrubasik, S; Roufogalis, B; Weiser, T | 1 |
| Fan, P; Liu, S; Sun, P; Tian, K; Wang, J; Xia, C; Yang, C; Zhou, J | 1 |
| Ang, L; Chen, J; Jin, J; Tian, Y; Wang, S; Wang, X | 1 |
| Daniels, R; Lunter, D | 1 |
| Holik, AK; Krammer, GE; Ley, JP; Pignitter, M; Rohm, B; Somoza, MM; Somoza, V; Zaunschirm, M | 1 |
| Daniels, R; Lunter, DJ; Rottke, M | 1 |
| Kohl-Bareis, M; Schak, M; Schiffer, T; Warnecke, JM; Wendt, T; Winkler, S | 1 |
| Hochkogler, CM; Hojdar, K; Krammer, GE; Ley, JP; Pignitter, M; Rohm, B; Somoza, V; Widder, S | 1 |
| Deng, P; Jiang, J; Kang, L; Liao, S; Liu, G; Liu, H; Mao, L | 1 |
| Krammer, GE; Ley, JP; Riedel, A; Rohm, B; Somoza, V; Widder, S | 1 |
| Bagoly, T; Boros, M; Helyes, Z; Horváth, K; Kemény, A; Kilár, F; Pintér, E; Sándor, V; Szolcsányi, J | 1 |
| Appendino, G; Caprioglio, D; De Petrocellis, L; Del Prete, D; Di Marzo, V; Minassi, A; Schiano-Moriello, A | 1 |
| Holik, AK; Krammer, GE; Kretschy, N; Ley, JP; Marko, D; Rohm, B; Somoza, MM; Somoza, V; Widder, S | 1 |
| Kasting, GB; Miller, MA | 1 |
| Gaubitz, M; Holm, C; Pisternick-Ruf, W; Richter, E; Schiffer, T; Weiser, T | 1 |
| Daniels, R; Herrmann, S; Lunter, D | 1 |
| Ding, X; Li, P; Ma, F; Yang, Q; Zhang, L; Zhang, Q; Zhang, W; Zhu, J | 1 |
| Holmberg, HC; Sperlich, B; Zinner, C | 1 |
| Daniels, R; Heck, R; Hermann, S; Lunter, DJ | 1 |
| Beltran, L; Hans, J; Hatt, H; Krammer, GE; Ley, JP; Lieder, B; Schwerzler, J; Somoza, V; Walker, J; Widder, S; Ziemba, PM | 1 |
| Berry, D; Bruk, A; Hans, J; Hochkogler, CM; Krammer, GE; Leitinger, A; Ley, JP; Lieder, B; Meier, SM; Pignitter, M; Riva, A; Rust, P; Somoza, V; Wagner, S; Widder, S | 1 |
| Bass, J; Canetti, EFD; Moro, C; Scott, AM | 1 |
| Daniels, R; Heck, R; Lukić, MŽ; Lunter, DJ; Savić, SD | 1 |
| Carpenter, GH; Hans, J; Houghton, JW; Ley, JP; Pesaro, M; Proctor, G | 1 |
| Kamiya, M; Kawatani, M; Takahashi, H; Urano, Y | 1 |
| Hans, J; Heiss, E; Hochkogler, CM; Krammer, GE; Ley, JP; Lieder, B; Schachner, D; Schröter, A; Somoza, V | 1 |
| Cui, ZG; Feng, QW; Inadera, H; Li, ML; Sun, L; Zakki, SA | 1 |
| Kushwaha, PK; Nagar, DP; Rao, PVL; Satpute, RM | 1 |
| Cao, W; Jiang, Y; Ma, D; Shi, H; Zhou, C | 1 |
| Daniels, R; Lunter, DJ; Schmidberger, M | 1 |
| Chaichompoo, W; Pantan, R; Sivasinprasasn, S; Suksamrarn, A; Tocharus, C; Tocharus, J; Wikan, N | 1 |
| Hans, J; Hoi, J; Klieber, M; Krammer, GE; Ley, JP; Lieder, B; Riedel, J; Rust, P; Ruzsanyi, V; Schweiger, K; Somoza, V; Stoeger, V | 1 |
| Chaichompoo, W; Kongkaew, A; Sivasinprasasn, S; Suksamrarn, A; Tocharus, C; Tocharus, J; Wikan, N | 1 |
| Cheng, J; Dong, H; Hua, J; Li, YY; Yuan, L; Yue, L; Zhang, H; Zhou, J | 1 |
| Bloch, W; Brinkmann, C; Schörkmaier, T; Wahl, P; Wahl, Y | 1 |
| Baranova, OA; Solov'eva, EY | 1 |
| Carlquist, M; Grey, C; Muratovska, N | 1 |
| Chen, J; Li, X; Tian, Y; Wei, W; Yu, W; Zhang, L; Zhao, J; Zhao, Y | 1 |
| Pointer, B; Rainville, P; Yang, J | 1 |
| Arroyo-Manzanares, N; Campillo, N; Hernández-Córdoba, M; López-García, I; Rodríguez-Palazón, MC; Viñas, P | 1 |
5 trial(s) available for nonivamide and capsaicin
| Article | Year |
|---|---|
The capsaicin analog nonivamide decreases total energy intake from a standardized breakfast and enhances plasma serotonin levels in moderately overweight men after administered in an oral glucose tolerance test: a randomized, crossover trial.
Topics: Adult; Appetite; Blood Glucose; Body Mass Index; Breakfast; Capsaicin; Cross-Over Studies; Energy Intake; Glucagon-Like Peptide 1; Glucose Tolerance Test; Humans; Hunger; Insulin; Male; Overweight; Peptide Fragments; Peptide YY; Serotonin; Young Adult | 2014 |
Analgesic topical capsaicinoid therapy increases somatostatin-like immunoreactivity in the human plasma.
Topics: Administration, Cutaneous; Aged; Analgesics; Capsaicin; Female; Humans; Low Back Pain; Male; Middle Aged; Pain Measurement; Somatostatin; Spinal Cord Diseases | 2014 |
Efficacy and safety of nicoboxil/nonivamide ointment for the treatment of acute pain in the low back - A randomized, controlled trial.
Topics: Acute Pain; Adolescent; Adult; Aged; Capsaicin; Double-Blind Method; Drug Combinations; Female; Humans; Low Back Pain; Male; Middle Aged; Nicotinic Acids; Treatment Outcome; Young Adult | 2016 |
A 12-week intervention with nonivamide, a TRPV1 agonist, prevents a dietary-induced body fat gain and increases peripheral serotonin in moderately overweight subjects.
Topics: Adiponectin; Adiposity; Adult; Blood Glucose; Body Composition; Body Mass Index; Body Weight; Capsaicin; Cholesterol; Diet; Dietary Fats; Female; Gastrointestinal Hormones; Gastrointestinal Microbiome; Humans; Insulin; Leptin; Male; Overweight; Postprandial Period; Satiation; Sensory System Agents; Serotonin; Triglycerides; TRPV Cation Channels; Weight Gain; Young Adult | 2017 |
Wheat Protein Hydrolysate Fortified With l-Arginine Enhances Satiation Induced by the Capsaicinoid Nonivamide in Moderately Overweight Male Subjects.
Topics: Adult; Arginine; Capsaicin; Cross-Over Studies; Energy Intake; Gastric Emptying; Humans; Male; Middle Aged; Overweight; Protein Hydrolysates; Satiation; Serotonin; Single-Blind Method; Triticum | 2019 |
81 other study(ies) available for nonivamide and capsaicin
| Article | Year |
|---|---|
Guaiacoxypropanolamine derivatives of capsaicin: a new family of beta-adrenoceptor blockers with intrinsic cardiotonic properties.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Capsaicin; Cardiotonic Agents; Guaiacol; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Propanolamines; Rats; Rats, Wistar | 1994 |
Analogues of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 1. The aromatic "A-region".
Topics: Analgesics; Animals; Calcium; Calcium Channel Agonists; Capsaicin; Female; Ganglia, Spinal; Guinea Pigs; Ileum; Male; Mice; Muscle Contraction; Structure-Activity Relationship | 1993 |
Analogues of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 2. The amide bond "B-region".
Topics: Analgesics; Animals; Calcium; Calcium Channel Agonists; Capsaicin; Ganglia, Spinal; Guinea Pigs; Ileum; Mice; Muscle Contraction; Structure-Activity Relationship | 1993 |
Analogues of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 3. The hydrophobic side-chain "C-region".
Topics: Analgesics; Animals; Calcium; Calcium Channel Agonists; Capsaicin; Ganglia, Spinal; Guinea Pigs; Ileum; Mice; Muscle Contraction; Structure-Activity Relationship | 1993 |
Similarities and differences in the structure-activity relationships of capsaicin and resiniferatoxin analogues.
Topics: Analgesics; Animals; Calcium; Capsaicin; Cell Membrane; Cells, Cultured; Diterpenes; Female; Ganglia, Spinal; Models, Molecular; Molecular Conformation; Molecular Structure; Neurotoxins; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1996 |
Cardiovascular effects of nonivamide succinate.
Topics: Animals; Blood Pressure; Capsaicin; Depression, Chemical; Guinea Pigs; Heart Rate; Hemodynamics; Male; Rats; Rats, Inbred Strains; Vanillic Acid; Vasodilation; Vasodilator Agents | 1991 |
Synthetic capsaicin reversibly impairs vasopressin-mediated blood pressure recovery.
Topics: Animals; Blood Pressure; Body Weight; Capsaicin; Captopril; Deamino Arginine Vasopressin; Eye; Heart Rate; Hydroxybenzoates; Methohexital; Ocular Physiological Phenomena; Pentolinium Tartrate; Potassium; Rats; Rats, Inbred Strains; Reference Values; Sodium; Species Specificity; Vanillic Acid; Water-Electrolyte Balance | 1989 |
Studies on the hypothermic response of capsaicin and its analogue in mice.
Topics: Animals; Body Temperature; Capsaicin; Hydroxybenzoates; Male; Mice; Peptides, Cyclic; Piperazines; Thyrotropin-Releasing Hormone; Time Factors; Vanillic Acid | 1986 |
Chemical irritant algesia assessed using the human blister base.
Topics: Blister; Bradykinin; Capsaicin; Dibenzoxazepines; Drug Interactions; Humans; Hydroxybenzoates; Nitriles; o-Chlorobenzylidenemalonitrile; Pain; Skin; Vanillic Acid | 1986 |
Micturition in the unanesthetized rat: effects of intrathecal capsaicin, N-vanillylnonanamide, 6-hydroxydopamine and 5,6-dihydroxytryptamine.
Topics: 5,6-Dihydroxytryptamine; Animals; Capsaicin; Hydroxybenzoates; Hydroxydopamines; Injections, Spinal; Male; Oxidopamine; Rats; Rats, Inbred Strains; Reflex; Urination; Vanillic Acid | 1988 |
[Effect of cysteamine on vocalization responses by arterial algogenics in guinea pigs].
Topics: Acetylcholine; Animals; Bradykinin; Capsaicin; Cysteamine; Guinea Pigs; Injections, Intra-Arterial; Injections, Intradermal; Male; Nociceptors; Vanillic Acid; Vocalization, Animal | 1988 |
[The effect of nonanoyl vanillylamide on the chemically-induced nociception].
Topics: Analgesics; Animals; Benzoquinones; Capsaicin; Dose-Response Relationship, Drug; Formaldehyde; Hydroxybenzoates; Injections, Subcutaneous; Male; Mice; Pain Measurement; Quinones; Stimulation, Chemical; Vanillic Acid | 1987 |
[Effects of serial administration of vanillyl n-nonoylamide on vocalization responses by arterial algogenics in guinea pigs].
Topics: Acetylcholine; Analgesics; Animals; Bradykinin; Capsaicin; Chemoreceptor Cells; Guinea Pigs; Hydroxybenzoates; Male; Nociceptors; Pain; Vanillic Acid; Vocalization, Animal | 1985 |
Comparison of nonivamide and capsaicin with regard to their pharmacokinetics and effects on sensory neurons.
Topics: Animals; Behavior, Animal; Blood Pressure; Capsaicin; Eye; Female; Hydroxybenzoates; Kinetics; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Somatostatin; Substance P; Vanillic Acid | 1984 |
Autonomic and sensory cardiovascular activities of nonivamide: intrathecal administration of clonidine.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Capsaicin; Cardiovascular System; Clonidine; Heart Rate; Infusions, Parenteral; Injections, Intra-Arterial; Injections, Intravenous; Male; Neurons, Afferent; Rats; Rats, Wistar; Spine; Substance P; Vanillic Acid | 1994 |
Cardiovascular interactions of nonivamide, glyceryl nonivamide, capsaicin analogues, and substance P antagonist in rats.
Topics: Animals; Blood Pressure; Capsaicin; Drug Interactions; Glycerol; Heart Rate; Hemodynamics; Indicators and Reagents; Injections, Intraperitoneal; Injections, Spinal; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Wistar; Substance P; Vagotomy; Vanillic Acid; Vasodilation | 1993 |
Desensitizing mechanism of capsaicin and nonanoyl vanillylamide on the vascular nociceptive response in the guinea pig.
Topics: Acetylcholine; Animals; Bradykinin; Capsaicin; Ganglia, Spinal; Guinea Pigs; Injections, Intra-Arterial; Injections, Spinal; Injections, Subcutaneous; Male; Pain; Spinal Cord; Substance P; Vanillic Acid; Vocalization, Animal | 1993 |
Capsaicin and its analogs induce ion channels in planar lipid bilayers.
Topics: Benzylamines; Capsaicin; Diterpenes; Electric Conductivity; Fatty Acids; Ion Channels; Lipid Bilayers | 1995 |
Percutaneous absorption of vanilloids: in vivo and in vitro studies.
Topics: Animals; Capsaicin; Humans; In Vitro Techniques; Male; Rats; Skin Absorption; Vanillic Acid | 1997 |
Development and evaluation of transdermal patches of nonivamide and sodium nonivamide acetate.
Topics: Administration, Cutaneous; Animals; Capsaicin; Chemical Phenomena; Chemistry, Physical; Excipients; In Vitro Techniques; Male; Rats; Rats, Wistar; Rubber; Skin Absorption; Vanillic Acid | 1997 |
A possible role of nitric oxide formation in the vasodilatation of rabbit ear artery induced by a topically applied Capsaicin analogue.
Topics: Administration, Topical; Animals; Arteries; Capsaicin; Dose-Response Relationship, Drug; Ear; Edema; Enzyme Inhibitors; Female; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Vasodilation | 1998 |
Transdermal delivery of sodium nonivamide propionate by iontophoresis.
Topics: Administration, Cutaneous; Animals; Capsaicin; Cellulose; Enzyme Inhibitors; Hydrogels; Hydrogen-Ion Concentration; Iontophoresis; Methylcellulose; Rats; Rats, Wistar; Skin Absorption | 1998 |
Nitrated nonivamide displaying a drawback of proton's role in capsaicin-associated sensory and neuronal activities.
Topics: Action Potentials; Amides; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Sensory; Ganglia, Spinal; Guinea Pigs; Heart Rate; Humans; In Vitro Techniques; Male; Myocardial Contraction; Neurons; Nitrates; Protons; Rats; Rats, Wistar; Vagotomy; Vagus Nerve; Vanillic Acid | 1999 |
The transepidermal oxygen flux from the environment is in balance with the capillary oxygen supply.
Topics: Adult; Air Pollutants; Capillaries; Capsaicin; Female; Humans; Hyperemia; Laser-Doppler Flowmetry; Male; Middle Aged; Ointments; Oxygen; Partial Pressure; Regional Blood Flow; Reproducibility of Results; Skin | 2000 |
Capsaicin and nonivamide as novel skin permeation enhancers for indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Enzyme Inhibitors; Female; In Vitro Techniques; Indomethacin; Irritants; Mice; Mice, Nude; Nitric Oxide Synthase; Skin; Skin Absorption; Skin Irritancy Tests; Ultrasonics | 2001 |
Determination of capsaicin, dihydrocapsaicin, and nonivamide in self-defense weapons by liquid chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry.
Topics: Capsaicin; Chromatography, High Pressure Liquid; Mass Spectrometry; Protective Devices; Reproducibility of Results; Sensitivity and Specificity | 2001 |
In vitro and in vivo evaluations of topically applied capsaicin and nonivamide from hydrogels.
Topics: Administration, Topical; Animals; Capsaicin; Enzyme Inhibitors; Epidermis; Erythema; Humans; Hydrogels; Mice; Mice, Nude; Ointments; Skin Absorption; Time Factors; Viscosity | 2001 |
In vitro topical application and in vivo pharmacodynamic evaluation of nonivamide hydrogels using Wistar rat as an animal model.
Topics: Administration, Topical; Animals; Capsaicin; Hydrogels; Male; Models, Animal; Rats; Rats, Wistar; Skin Absorption | 2002 |
Determination of capsaicin, nonivamide, and dihydrocapsaicin in blood and tissue by liquid chromatography-tandem mass spectrometry.
Topics: Administration, Inhalation; Animals; Calibration; Capsaicin; Chromatography, Liquid; Male; Mass Spectrometry; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity | 2002 |
Improved dorsal random-pattern skin flap survival in rats with a topically applied combination of nonivamide and nicoboxil.
Topics: Administration, Topical; Animals; Capsaicin; Drug Therapy, Combination; Graft Survival; Male; Neovascularization, Physiologic; Nicotinic Acids; Rats; Rats, Wistar; Surgical Flaps | 2003 |
[Studies on the physiological effect of an ointment containing nonylic acid vanillylamide and nicotinic acid beta-butoxyethyl ester].
Topics: Capsaicin; Irritants; Niacin; Nicotinic Acids; Ointments | 1961 |
Local heating of human skin by millimeter waves: effect of blood flow.
Topics: Capsaicin; Electromagnetic Fields; Energy Transfer; Fingers; Forearm; Forecasting; Humans; Hyperthermia, Induced; Models, Biological; Nicotinic Acids; Regional Blood Flow; Skin; Skin Temperature; Thermal Conductivity; Vasodilator Agents | 2005 |
The taming of capsaicin. Reversal of the vanilloid activity of N-acylvanillamines by aromatic iodination.
Topics: Bromine; Calcium; Capsaicin; Cell Line; Chlorine; Diterpenes; Humans; Iodine; Ion Channels; Structure-Activity Relationship; TRPV Cation Channels | 2005 |
TRPV1 antagonists elevate cell surface populations of receptor protein and exacerbate TRPV1-mediated toxicities in human lung epithelial cells.
Topics: Benzoates; Brefeldin A; Bronchi; Calcium; Capsaicin; Cell Survival; Cells, Cultured; Drug Administration Schedule; Drug Synergism; Epithelial Cells; Gene Expression; Humans; Interleukin-6; Interleukin-8; Nitric Oxide Synthase; Oxazoles; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; TRPV Cation Channels | 2006 |
Electrically-assisted skin permeation of two synthetic capsaicin derivatives, sodium nonivamide acetate and sodium nonivamide propionate, via rate-controlling polyethylene membranes.
Topics: Administration, Cutaneous; Animals; Capsaicin; Chemical Phenomena; Chemistry, Physical; Electroporation; Female; In Vitro Techniques; Iontophoresis; Membranes, Artificial; Mice; Mice, Nude; Microscopy, Electron, Scanning; Molecular Weight; Polyethylenes; Skin | 2005 |
Analysis of eight capsaicinoids in peppers and pepper-containing foods by high-performance liquid chromatography and liquid chromatography-mass spectrometry.
Topics: California; Capsaicin; Capsicum; Chromatography, High Pressure Liquid; Food Analysis; Fruit; Water | 2005 |
Effect of topical application of capsaicin and its related compounds on dermal insulin-like growth factor-I levels in mice and on facial skin elasticity in humans.
Topics: Administration, Topical; Animals; Arachidonic Acids; Capsaicin; Dermis; Elasticity; Endocannabinoids; Face; Female; Humans; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Polyunsaturated Alkamides; Skin | 2007 |
Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells.
Topics: Activating Transcription Factor 3; Arachidonic Acids; Calcium; Capsaicin; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cinnamates; Cyclin D1; Cyclin G2; Cyclins; Diterpenes; Dithiothreitol; Endocannabinoids; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Epithelial Cells; Eukaryotic Initiation Factor-2; Gene Expression; Humans; Lung; Phosphorylation; Polyunsaturated Alkamides; Thapsigargin; Thiourea; Transcription Factor CHOP; Transfection; TRPV Cation Channels | 2007 |
Transdermal delivery of capsaicin derivative-sodium nonivamide acetate using microemulsions as vehicles.
Topics: Administration, Cutaneous; Animals; Capsaicin; Electric Conductivity; Emulsions; In Vitro Techniques; Particle Size; Pharmaceutical Vehicles; Rats; Skin Absorption; Surface-Active Agents; Viscosity | 2008 |
A comparison of pretreatment with a topical combination of nonivamide and nicoboxil and surgical delay in a random pattern skin flap model.
Topics: Administration, Topical; Animals; Capsaicin; Drug Therapy, Combination; Male; Necrosis; Nicotinic Acids; Random Allocation; Rats; Rats, Wistar; Sensory System Agents; Surgical Flaps | 2009 |
Protective effect and relation structure-activity of nonivamide and iododerivatives in several models of lipid oxidation.
Topics: Animals; Antioxidants; Capsaicin; Cell Line; Cholesterol, LDL; Cytotoxins; Iodine; Lipid Peroxidation; Molecular Structure; Oxidation-Reduction; Structure-Activity Relationship; Swine | 2009 |
Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists.
Topics: Animals; Calcium; Capsaicin; Halogenation; Intracellular Space; Lasers; Ligands; Light; Membrane Potentials; Photolysis; Rats; Rats, Wistar; Trigeminal Nerve; TRPV Cation Channels | 2009 |
Molecular dynamics at ambient and elevated pressure of the amorphous pharmaceutical: nonivamide (pelargonic acid vanillylamide).
Topics: Benzylamines; Capsaicin; Dielectric Spectroscopy; Fatty Acids; Glass; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Pressure; Sensory System Agents; Temperature; X-Ray Diffraction | 2011 |
Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury.
Topics: Animals; Bronchi; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Death; Cell Line; Cell Line, Transformed; Cells, Cultured; Endoplasmic Reticulum Stress; Humans; Inflammation; L-Lactate Dehydrogenase; Lipopolysaccharides; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Alveoli; Pulmonary Edema; Transcription Factor CHOP; TRPV Cation Channels | 2012 |
Determination and pharmacokinetics of [6]-gingerol in mouse plasma by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Area Under Curve; Capsaicin; Catechols; Chromatography, High Pressure Liquid; Drug Stability; Fatty Alcohols; Least-Squares Analysis; Male; Mice; Mice, Inbred ICR; Reproducibility of Results; Tandem Mass Spectrometry | 2012 |
New film forming emulsions containing Eudragit® NE and/or RS 30D for sustained dermal delivery of nonivamide.
Topics: Acrylic Resins; Administration, Cutaneous; Animals; Capsaicin; Chemistry, Pharmaceutical; Delayed-Action Preparations; Emulsions; Glass; Hypromellose Derivatives; Methacrylates; Methylcellulose; Permeability; Polycarboxylate Cement; Polymers; Polysorbates; Polyvinyl Alcohol; Povidone; Skin; Skin Cream; Surface-Active Agents; Swine; Transition Temperature | 2012 |
Comparison of the effects of pelargonic acid vanillylamide and capsaicin on human vanilloid receptors.
Topics: Animals; Benzylamines; Capsaicin; Fatty Acids; HEK293 Cells; Humans; TRPV Cation Channels | 2013 |
Toxic effects of environment-friendly antifoulant nonivamide on Phaeodactylum tricornutum.
Topics: Capsaicin; Catalase; Chloroplasts; Diatoms; Disinfectants; Glutathione; Mitochondria; Peroxidases; Photosynthesis; Reactive Oxygen Species; Superoxide Dismutase; Water Pollutants, Chemical | 2013 |
[A novel method for the identification of illegal cooking oil (1): detection of three capsaicinoids with liquid chromatography-mass spectrometry].
Topics: Capsaicin; Capsicum; Chromatography, Liquid; Cooking; Mass Spectrometry; Oils | 2012 |
In vitro skin permeation and penetration of nonivamide from novel film-forming emulsions.
Topics: Animals; Capsaicin; Ear; Emulsions; In Vitro Techniques; Sensory System Agents; Skin; Skin Absorption; Swine | 2013 |
Nonivamide, a capsaicin analog, increases dopamine and serotonin release in SH-SY5Y cells via a TRPV1-independent pathway.
Topics: Capsaicin; Cell Line, Tumor; Cell Survival; Cyclohexanols; Dopamine; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Sensory System Agents; Serotonin; Signal Transduction; TRPV Cation Channels | 2013 |
In vitro studies on release and skin permeation of nonivamide from novel oil-in-oil-emulsions.
Topics: Animals; Capsaicin; Castor Oil; Dimethylpolysiloxanes; Emulsions; Oils; Permeability; Silicones; Skin; Skin Absorption; Surface-Active Agents; Swine | 2014 |
Evaluation of changes in the haemoglobin of skin and muscle tissue of the calf, as induced by topical application of a nonivamide/nicoboxil cream.
Topics: Adult; Capsaicin; Hemoglobins; Humans; Male; Muscle, Skeletal; Nicotinic Acids; Skin; Skin Cream | 2014 |
[Efficiency evaluation of capsaicinoids to discriminate bio-waste oils from edible vegetable oils].
Topics: Capsaicin; Cooking; Food; Oils; Peanut Oil; Plant Oils; Solid Waste; Vegetables | 2014 |
Capsaicin, nonivamide and trans-pellitorine decrease free fatty acid uptake without TRPV1 activation and increase acetyl-coenzyme A synthetase activity in Caco-2 cells.
Topics: Acetate-CoA Ligase; Benzaldehydes; Caco-2 Cells; Capsaicin; Cell Survival; Dietary Supplements; Down-Regulation; Enterocytes; Epithelial Sodium Channels; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Gastrointestinal Agents; Humans; Hypolipidemic Agents; Intestinal Absorption; Kinetics; Polyunsaturated Alkamides; TRPV Cation Channels | 2015 |
Discovery of non-electrophilic capsaicinoid-type TRPA1 ligands.
Topics: Calcium Channels; Capsaicin; Drug Discovery; HEK293 Cells; Humans; Ligands; Nerve Tissue Proteins; Sensory System Agents; Structure-Activity Relationship; Tetrazoles; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2015 |
Nonivamide enhances miRNA let-7d expression and decreases adipogenesis PPARγ expression in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipogenesis; Animals; Capsaicin; Mice; MicroRNAs; PPAR gamma; TRPV Cation Channels | 2015 |
A spreadsheet-based method for simultaneously estimating the disposition of multiple ingredients applied to skin.
Topics: Administration, Cutaneous; Capsaicin; Computer Simulation; Humans; Models, Biological; Pharmaceutical Vehicles; Propylene Glycol; Skin; Skin Absorption; Software; Solubility; Thermodynamics; Volatilization | 2015 |
Methods for the determination of the substantivity of topical formulations.
Topics: Administration, Cutaneous; Animals; Capsaicin; Delayed-Action Preparations; Drug Compounding; Emulsions; Oils; Sensory System Agents; Skin; Skin Absorption; Skin Cream; Swine | 2017 |
Quantitative determination of major capsaicinoids in serum by ELISA and time-resolved fluorescent immunoassay based on monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Biosensing Techniques; Capsaicin; Chromatography, Affinity; Enzyme-Linked Immunosorbent Assay; Female; Fluorescence; Fluorescent Antibody Technique; Humans; Limit of Detection; Mice, Inbred BALB C; Rabbits; Rats; Vanillic Acid | 2016 |
Topical application of cream containing nonivamide and nicoboxil does not enhance the performance of experienced cyclists during a 4-km time-trial.
Topics: Adult; Bicycling; Capsaicin; Heart Rate; Humans; Lactic Acid; Male; Muscle, Skeletal; Nicotinic Acids; Oxygen; Temperature; Thigh | 2016 |
Film-forming formulations containing porous silica for the sustained delivery of actives to the skin.
Topics: Administration, Cutaneous; Animals; Antipruritics; Capsaicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Humans; Microscopy, Confocal; Models, Animal; Oils; Permeability; Polymers; Porosity; Pruritus; Silicon Dioxide; Skin; Skin Absorption; Spectrum Analysis, Raman; Swine | 2016 |
Nonivamide, a capsaicin analogue, exhibits anti-inflammatory properties in peripheral blood mononuclear cells and U-937 macrophages.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cell Line; Cytokines; Fatty Acids, Unsaturated; Humans; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; NF-kappa B; Polyunsaturated Alkamides; Transient Receptor Potential Channels; Tumor Necrosis Factor-alpha | 2017 |
Enhancing capillary blood collection: The influence of nicotinic acid and nonivamide.
Topics: Adolescent; Adult; Blood Specimen Collection; Capillaries; Capsaicin; Female; Flow Cytometry; Humans; Leukocytes; Male; Niacin; Vasodilation; Vasodilator Agents; Young Adult | 2017 |
Ex vivo skin permeation and penetration of nonivamide from and in vivo skin tolerability of film-forming formulations containing porous silica.
Topics: Administration, Cutaneous; Animals; Capsaicin; Chromatography, High Pressure Liquid; Drug Carriers; Drug Compounding; Drug Liberation; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Oils; Permeability; Polymers; Porosity; Silicon Dioxide; Skin Absorption; Swine | 2017 |
Sensory effects of transient receptor potential channel agonists on whole mouth saliva extensional rheology.
Topics: Acrolein; Adult; Capsaicin; Female; Flavoring Agents; Healthy Volunteers; Humans; Male; Menthol; Mouth; Mouthwashes; Rheology; Saliva; Sensory System Agents; Transient Receptor Potential Channels; Young Adult | 2017 |
Factors affecting the uncaging efficiency of 500 nm light-activatable BODIPY caging group.
Topics: Benzylamines; Boron Compounds; Calcium; Capsaicin; Fatty Acids; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Light; Solvents; TRPV Cation Channels | 2018 |
Capsaicin and nonivamide similarly modulate outcome measures of mitochondrial energy metabolism in HepG2 and 3T3-L1 cells.
Topics: 3T3-L1 Cells; Animals; Capsaicin; Energy Metabolism; Fatty Acids; Glucose; Hep G2 Cells; Humans; Lipid Metabolism; Mice; Mitochondria; Oxygen | 2018 |
Mechanistic study of nonivamide enhancement of hyperthermia-induced apoptosis in U937 cells.
Topics: Apoptosis; Capsaicin; Humans; Hyperthermia, Induced; Membrane Potential, Mitochondrial; Reactive Oxygen Species; U937 Cells | 2018 |
Comparative safety evaluation of riot control agents of synthetic and natural origin.
Topics: Administration, Inhalation; Alanine Transaminase; Animals; Aspartate Aminotransferases; Capsaicin; Dibenzoxazepines; Irritants; Lethal Dose 50; Liver; Lung; Male; Mice; Plant Extracts; Respiration; Riot Control Agents, Chemical | 2018 |
Fast simultaneous determination of capsaicin, dihydrocapsaicin and nonivamide for detecting adulteration in edible and crude vegetable oils by UPLC-MS/MS.
Topics: Capsaicin; Chromatography, High Pressure Liquid; Food Contamination; Liquid-Liquid Extraction; Plant Oils; Solid Phase Extraction; Tandem Mass Spectrometry | 2018 |
Method to determine the impact of substantivity on ex vivo skin-permeation.
Topics: Administration, Cutaneous; Administration, Topical; Animals; Capsaicin; Clothing; Dermatologic Agents; Diffusion Chambers, Culture; Drug Compounding; Drug Delivery Systems; Emulsions; Enzyme Inhibitors; In Vitro Techniques; Ointments; Skin; Skin Absorption; Swine | 2018 |
Synergistic effects of the capsaicinoid nonivamide and rosuvastatin on obesity-related endothelial dysfunction in rat fed a high-fat diet.
Topics: Animals; Anti-Obesity Agents; Aorta; Blood Pressure; Capsaicin; Diet, High-Fat; Drug Synergism; Drug Therapy, Combination; Insulin Resistance; Male; Obesity; Oxidative Stress; Rats, Sprague-Dawley; Rosuvastatin Calcium | 2019 |
Capsaicinoid nonivamide improves nonalcoholic fatty liver disease in rats fed a high-fat diet.
Topics: Aldehydes; Animals; Apoptosis; Capsaicin; Capsicum; Caspase 3; Diet, High-Fat; Glucose Transporter Type 2; Lipid Peroxidation; Liver; Male; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phytotherapy; Rats, Sprague-Dawley; Rosuvastatin Calcium; Sterol Regulatory Element Binding Protein 1; TRPV Cation Channels | 2020 |
Inhibition of N-Vanillylnonanamide in anaerobic digestion of lipids in food waste: Microorganisms damage and blocked electron transfer.
Topics: Anaerobiosis; Bioreactors; Capsaicin; Electrons; Food; Methane; Refuse Disposal; RNA, Ribosomal, 16S; Sewage; Vanillic Acid | 2020 |
No Influence of Nonivamide-nicoboxil on the Peak Power Output in Competitive Sportsmen.
Topics: Administration, Cutaneous; Adult; Athletic Performance; Capsaicin; Cross-Over Studies; Exercise Test; Humans; Hypoxia; Lactic Acid; Muscle Strength; Muscle, Skeletal; Nicotinic Acids; Oxygen Consumption; Physical Endurance; Skin Cream; Spectroscopy, Near-Infrared; Young Adult | 2021 |
[Real-world clinical efficacy assessment of Kapsikam a combined topical medication based on nonivamide synthetic capsaicin analog in patients with acute nonspecific musculoskeletal back pain: LOCUS observational study outcomes].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Capsaicin; Humans; Treatment Outcome | 2021 |
Engineering Saccharomyces cerevisiae for production of the capsaicinoid nonivamide.
Topics: Acyltransferases; Capsaicin; Capsicum; Coenzyme A; Fruit; Ligases; Saccharomyces cerevisiae | 2022 |
Nonivamide induces brown fat-like characteristics in porcine subcutaneous adipocytes.
Topics: Adipocytes, Beige; Adipocytes, Brown; Adipocytes, White; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Capsaicin; Diabetes Mellitus, Type 2; Humans; Obesity; Swine; Thermogenesis | 2022 |
Separation of Nonivamide and Capsaicin by Ultrahigh-Performance Liquid Chromatography for Routine Analysis of Capsaicinoids in Capsicum Products.
Topics: Camphor; Capsaicin; Capsicum; Chromatography, High Pressure Liquid; Chromatography, Liquid; Menthol; Vegetables; Water | 2023 |
Dispersive magnetic solid-phase extraction for capsaicinoid compounds in human serum using LC-HRMS: targeted and non-targeted approaches.
Topics: Capsaicin; Chromatography, High Pressure Liquid; Humans; Magnetic Phenomena; Mass Spectrometry; Nanotubes, Carbon; Solid Phase Extraction | 2023 |