nocodazole and paclitaxel

nocodazole has been researched along with paclitaxel in 466 studies

Research

Studies (466)

TimeframeStudies, this research(%)All Research%
pre-199051 (10.94)18.7374
1990's135 (28.97)18.2507
2000's166 (35.62)29.6817
2010's109 (23.39)24.3611
2020's5 (1.07)2.80

Authors

AuthorsStudies
Baasner, S; Beckers, T; Böhmer, FD; Burger, AM; Bürgermeister, J; Fiebig, HH; Frieser, M; Hockemeyer, J; Hufsky, H; Lyssenko, A; Mahboobi, S; Paper, DH; Pongratz, H1
Burger, AM; Camacho Gomez, JA; Düssmann, H; Günther, EG; Hirano, T; Ishii, Y; Prehn, JH; Prinz, H; Schmidt, P; Stoiber, T; Umezawa, K; Unger, E1
Bigelow, D; Canfield, LM; Gunatilaka, AA; Pierson, LS; Turbyville, TJ; VanEtten, HD; Whitesell, L; Wijeratne, EM; Zhang, Z1
Baasner, S; Böhm, KJ; Gerlach, M; Günther, EG; Müller, K; Prinz, H; Schmidt, P; Unger, E; Zuse, A2
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Baasner, S; Böhm, KJ; Gerlach, M; Günther, EG; Müller, K; Prinz, H; Schmidt, P; Unger, E2
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Hergenrother, PJ; Miller, MJ; Miller, PA; Moraski, GC; Palchaudhuri, R; Peterson, RJ; Stefely, JA1
Baasner, S; Böhm, KJ; Gerlach, M; Günther, EG; Müller, K; Nickel, HC; Prinz, H; Schmidt, P; Unger, E1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Aicher, B; Amon, P; Böhm, KJ; Chamasmani, B; Gerlach, M; Günther, EG; Ivanov, I; Müller, K; Prinz, H; Vogel, K1
Kalivendi, SV; Kamal, A; Kumar, GB; Reddy, MK; Reddy, VS; Shaik, TB; Srikanth, YV1
Lama, R; Li, B; Sandhu, R; Su, B; Zhong, B1
Arnold, E; Kaul, M; Kerrigan, JE; LaVoie, EJ; Parhi, AK; Pilch, DS; Tuske, S; Zhang, Y1
Kaul, M; Kelley, C; LaVoie, EJ; Parhi, A; Pilch, DS; Zhang, Y1
Addlagatta, A; Jain, N; Kalivendi, SV; Kishor, C; Kumar, AS; Murthy, TR; Ramesh, D; Reddy, MA; Sreedhar, B; Supriya, B1
Giurleo, D; Kaul, M; LaVoie, EJ; Parhi, A; Pilch, DS; Zhang, Y1
Akula, B; Bharathi, EV; Billa, VK; Cosenza, SC; Gallo, JM; Lv, H; Mallireddigari, MR; Padgaonkar, A; Pallela, VR; Reddy, EP; Reddy, MV; Subbaiah, DR1
Caboni, L; Carr, M; Knox, AJ; Meegan, MJ; Nathwani, SM; O'Boyle, NM; Pollock, JK; Wang, S; Zisterer, DM1
Capuano, B; DeBono, A; Scammells, PJ1
Bantu, R; Gurrala, S; Jain, N; Nagarapu, L; Polepalli, S; Srujana, G; Yadagiri, B1
Li, S; Li, Z; Meng, X; Pan, L; Su, B; Yang, S; Yu, S; Zhang, C; Zhong, B1
Babaev, VM; Belenok, MG; Kataev, VE; Mironov, VF; Rizvanov, IKh; Semenov, VV; Semenova, MN; Strobykina, IY1
Madala, HR; Mikelis, C; Punganuru, SR; Samala, R; Srivenugopal, KS; Venugopal, SN1
Lee, H; Srivastava, V1
Bai, R; Betancourt, T; Dasari, R; Frail, SK; Frolova, LV; Hamel, E; Hill, RM; Kornienko, A; LaBarbera, DV; Medellin, DC; Ontiveros, SJ; Pelly, SC; Rogelj, S; Scott, R; Shuster, CB; van Otterlo, WA; Zhou, Q1
Cao, SL; Ding, PP; Gao, M; Li, J; Li, Z; Li, ZF; Liao, J; Liu, CH; Mao, BB; Wang, H; Xu, X; Yang, CR; Zhao, H1
Ji, L; Li, Z; Lu, D; Meng, X; Yang, J; Yang, S; Yu, S; Zhou, S1
Meegan, MJ; Nathwani, S; O'Boyle, NM; Twamley, B; Zisterer, DM1
Abadleh, M; Abbassi, RH; Day, BW; Döbber, A; Johns, TG; Munoz, L; Peifer, C; Phoa, AF; Stringer, BW1
Bagul, C; Bhattacharjee, D; Jain, N; Kamal, A; Kapure, JS; Shaik, SP; Subba Rao, AV; Sultana, F; Vishnuvardhan, MVPS1
Babu, KS; Jain, N; Misra, S; Poornima, B; Shankaraiah, G; Siva, B; Venkanna, A; Yadav, DK1
Cheong, JE; Chung, I; Jernigan, FE; Sun, L; Wang, Y; Xu, Y; Zaffagni, M; Zetter, BR1
Cao, SL; Jiang, W; Li, J; Li, YS; Li, Z; Liao, J; Peng, B; Ren, TT; Wang, FC; Wang, G; Wang, H; Xu, S; Xu, X; Yang, CR1
Alfano, G; Altucci, L; Amet, R; Baldari, C; Barasoain, I; Brindisi, M; Brogi, S; Butini, S; Campiani, G; Chemi, G; Conte, M; de Asís Balaguer, F; Diaz, JF; Gemma, S; Grillo, A; Ibrahim, O; Khan, T; Kinsella, P; Lopresti, L; Lucena-Agell, D; Magnano, S; Menchon, G; Morbidelli, L; Nebbioso, A; Novellino, E; O'Sullivan, J; Olieric, N; Prota, AE; Spaccapelo, R; Steinmetz, MO; Ulivieri, C; Zisterer, DM1
Dank, C; Dzubak, P; Fuerst, R; Gurska, S; Hajduch, M; Kauderer, M; Mokshyna, O; Nowikow, C; Polishchuk, P; Rehulka, J; Rinner, U; Schmid, W; Zupkó, I1
Chein, RJ; Chen, JJW; Cheng, TR; Chou, TH; Chung, WC; Hong, TM; Lee, TC; Lin, MS; Tsai, ML; Weng, CW; Wong, CH; Yang, PC; Yang, SC1
Liu, Y; Xu, Z; Zhao, SJ1
Kaieda, A; Kokubu, Y; Miyamoto, K; Miyamoto, M; Nagino, T; Oikawa, T; Oki, A; Saito, B; Sakurai, H; Sameshima, T; Sasa, K; Takada, H; Tawada, M; Tozawa, R1
Afonso, C; Almeida, JDP; Bousbaa, H; Cidade, H; Henriques, AC; Machado, CM; Moreira, J; Pinto, M; Pinto, P; Salvador, JAR; Silva, PMA; Soares, JX1
Kimura, KI; Koshino, H; Kurisawa, N; Onodera, T; Toda, T; Yukawa, M1
Džubák, P; Gurská, S; Hajdúch, M; Hlaváč, J; Hradil, P; Krejčí, P; Řehulka, J; Vychodilová, K1
Kolonias, D; Lampidis, TJ; Rubin, RW; Savaraj, N1
De Mey, JR; Kreis, TE; Rickard, JE; Wacker, IU1
McGuinness, MP; Orth, JM1
Arregui, C; Barra, HS; Busciglio, J; Caceres, A1
Oliver, MG; Specian, RD1
Kuriyama, R; Leslie, R; Maekawa, T1
Kreis, TE; Rickard, JE2
Burmeister, DW; Goldberg, DJ; Rivas, RJ1
Ault, JG; DeMarco, AJ; Rieder, CL; Salmon, ED1
Smalheiser, NR1
Castro, M; Leven, RM; Tablin, F1
Matlin, KS; van Zeijl, MJ1
Kristensson, K; Lycke, E; Röyttä, M; Svennerholm, B; Vahlne, A1
Johansen, T; Nielsen, EH1
Chen, LB; Ferguson, M; Lee, C1
Danowski, BA1
Anstrom, JA1
Bornens, M; Celati, C; Paintrand, M1
Kreutzberg, GW; Lucas, CA1
Howlett, SK; Maro, B; Webb, M1
Menon, KM; Rajan, VP1
Eichenlaub-Ritter, U1
Keller, HU; Zimmermann, A1
Goodall, H; Maro, B1
Gely, C; Wright, M1
De Bruyne, GK; Dziedzic-Goclawska, A; Grzesik, W; Kieler, J; Lenczowski, S; Mareel, MM; Ostrowski, K; Rozycka, M; Strojny, P1
Aerts, F; De Brabander, M; De Mey, J; Geuens, G; Nuydens, R; Willebrords, R1
Cereijido, M; Gundersen, D; Misek, DE; Rodriguez-Boulan, E; Salas, PJ; Vega-Salas, DE1
Johnson, MH; Maro, B1
Carnegie, JA; Dardick, I; Tsang, BK1
Ivanov, IE; Rindler, MJ; Sabatini, DD1
Albertini, DF1
Lessman, CA1
Bulinski, JC; Gundersen, GG; Khawaja, S1
Aletta, JM; Greene, LA1
Bré, MH; Karsenti, E; Kreis, TE1
Wadsworth, P1
Alvarado, J; Polansky, J; Ryder, MI; Weinreb, RN1
De Brabander, M; Geerts, H; Hopkins, CR; Nuydens, R1
McIntosh, JR; Stemple, DL; Sweet, SC; Welsh, MJ1
Niederman, R; Ryder, MI; Weinreb, RN1
Boisvieux-Ulrich, E; Chailley, B; Laine, MC; Lemullois, M; Sandoz, D1
Ken, J; Wolf, P1
Habibi, HR; Lessman, CA; Macrae, TH1
de Pennart, H; Houliston, E; Maro, B1
Albertini, DF; Clark, JI1
Cleveland, DW; Kirschner, MW; Lopata, MA; Sherline, P1
De Brabander, M; De Mey, J; Geuens, G; Nuydens, R; Willebrords, R2
Borisy, GG; Bulinski, JC; De Brabander, M; De Mey, J; Geuens, G1
Hamel, E; Lin, CM1
Hii, CS; Howell, SL; Shaikh, S; Tyhurst, M1
de Brabander, M; De Mey, J; Geuens, G; Nuydens, R1
Albertini, DF; Herman, B1
Christen, P; Jaussi, R; Skoda, RC1
Albertini, DF; Herman, B; Langevin, MA1
Bornens, M; Maro, B; Paintrand, M; Paulin, D; Sauron, ME1
Cohen, WD; Joseph-Silverstein, J1
Hay, ED; Tomasek, JJ1
Bellairs, R; De Bruyne, G; Mareel, M; Van Peteghem, MC1
Maro, B; Pickering, SJ1
Burnside, B; O'Connor, P1
Cleveland, DW; Lopata, MA; Pittenger, MF1
Elson, EL; Kolodney, MS1
Avitabile, E; Campadelli-Fiume, G; Di Gaeta, S; Roizman, B; Torrisi, MR; Ward, PL1
Fujiwara, Y; Inomata, M; Kaneko, A; Kawashima, K; Kunikane, H; Saijo, N; Tanaka, Y1
Paul, EC; Quaroni, A1
Albrecht, H; Jongeneel, CV; Schook, LB1
Raymond, MN; Robin, P; Rossignol, B2
Cambiazo, V; González, M; Maccioni, RB1
Kaddurah-Daouk, R; Martin, KJ; Teicher, BA; Vassallo, CD1
Ingber, DE; Langer, R; Mooney, DJ1
Picart, R; Tixier-Vidal, A; Tougard, C; Van De Moortele, S1
Behrens, BC; Ding, M; Robinson, JM; Vandré, DD1
Betz, H; Kirsch, J1
Reese, TS; Terasaki, M1
Carré, D; Chang, P; Houliston, E; Rouvière, C; Sardet, C1
Erusalimsky, JD; Hancock, V; Hong, Y; Martin, JF; van der Loo, B1
Hamm-Alvarez, SF; Kim, PY; Sheetz, MP1
De Baetselier, P; De Braekeleer, J; Dewit, J; Schirrmacher, V; Verschueren, H1
Farshori, PQ; Goode, D1
Allan, AM; Harris, RA; McQuilkin, SJ; Mihic, SJ; Whatley, VJ1
Fairchild, CR; Long, BH1
Bamburg, JR; Bedford, JS; Jha, MN1
Minshull, J; Murray, AW; Sun, H; Tonks, NK1
Driever, W; Solnica-Krezel, L1
Andreassen, PR; Margolis, RL1
Smith, CL1
Rozhin, J; Sameni, M; Sloane, BF; Ziegler, G1
Hasegawa, T1
Clarke, HJ; Harrouk, W1
Antony, C; Kubiak, JZ; Maro, B; Zernicka-Goetz, M1
Audebert, S; Denoulet, P; Desbruyères, E; Eddé, B; Gros, F; Gruszczynski, C; Koulakoff, A1
Tritton, TR; Vichi, PJ1
Sanger, JM; Sanger, JW; Waterman-Storer, CM1
Lamppu, DM; Park, S; Price, BD; Tishler, RB1
Gundersen, GG; Gurland, G1
Delon, J; Legendre, P1
Gundersen, GG; Liao, G; Nagasaki, T1
Grassmé, HU; Ireland, RM; van Putten, JP1
Armstrong, L; Bushel, P; Catino, JJ; Kim, JH; Kumar, CC1
Aderem, A; Rosen, A; Veis, N1
Duesbery, NS; Masui, Y1
Avila, J; Ulloa, L1
Carnes, D; Colgan, SP; D'Andrea, L; Hofman, P; Madara, JL1
Catravas, JD; Go, C; Jilling, T; Marczin, N; Papapetropoulos, A1
Benezra, R; Li, Y1
Czihak, G; Dr-aber, P; Dráberová, E; Nováková, M; Schürmann, W; Viklický, V1
Baumgart, E; Burkhardt, JK; Fahimi, HD; Lüers, G; Schrader, M; Spring, H; Völkl, A1
Fishkind, DJ; Silverman, JD; Wang, YL1
Brattsand, G; Gradin, HM; Gullberg, M; Larsson, N; Marklund, U1
Andreassen, PR; Lacroix, FB; Margolis, RL; Trielli, MO1
Becker, E; Bershadsky, A; Chausovsky, A; Geiger, B; Lyubimova, A1
Hamm-Alvarez, SF; Loran-Goss, K; Shen, WC; Sonee, M1
Ashton, AC; Dolly, JO1
Deerinck, TJ; Ellisman, MH; Subramani, S; Wenzel, T; Wiemer, EA1
Andreassen, PR; Margolis, RL; Martineau, SN1
Kennedy, BP; Pruzanski, W; Stefanski, E; Vadas, P; van den Bosch, H1
Keller, R; Lane, MC1
Ebersold, MW; Helenius, A; Sodeik, B1
Barra, Y; Bourgarel, V; Braguer, D; Briand, C; el Khyari, S1
Oelschlaeger, TA; Tall, BD1
Asada, S; Goto, K; Hama, H; Inada, T; Kasuya, Y; Ozawa, F1
Caron, JM1
Alieva, IB; Vorobjev, IA1
Magnusson, MK; Mosher, DF; Zhang, Q1
Bement, WM; Canman, JC1
Webster, DR1
McCaig, C; Rajnicek, A1
Dunn, GA; Fraylich, PE; Zicha, D1
Haavisto, A; Hewitson, L; Jones, J; Schatten, G; Simerly, C1
Chung, KS; Day, BN; Kim, NH1
Chau, MS; Hunter, T; Poon, RY; Yamashita, K1
Lange, CS; Stevenson, AF1
Ainger, K; Barbarese, E; Carson, JH; Worboys, K1
De Zeeuw, CI; Galjart, N; Goedknegt, E; Grosveld, F; Hertzberg, E; Hoogenraad, CC; Neubauer, A1
Lessman, CA; Wang, T1
Dondua, AK; Fedorova, ZE; Kostyuchenko, RP1
Koretsky, VV; Nadezhdina, ES; Severin, FF; Shanina, NA; Shevchenko, A; Solovyanova, OB1
Rao, GH; White, JG1
Fojo, T; Foster, JS; Giannakakou, P; Ichijo, H; Wang, HS; Wang, TH; Wimalasena, J1
Kuhn, M1
Rösner, H; Vacun, G1
Basu, A; Croce, CM; Haldar, S1
Ikegami, R; Rivera-Bennetts, AK; Yager, TD; Zhang, J1
Cho-Chung, YS; Korsmeyer, SJ; Longo, DL; Nesterova, M; Srivastava, AR; Srivastava, RK1
Braguer, D; Briand, C; Kadi, A; Lehmann, M; Luis, J; Marvaldi, J; Pichard, V; Rognoni, JB1
Hartigan, JA; Johnson, GV; Jope, RS; Litersky, JM; Xie, H1
Ling, YH; Perez-Soler, R; Tornos, C1
Wang, N1
Leite, R; Webb, RC1
Fitzpatrick, FA; Moos, PJ1
Gerke, V; Kielbassa, K; Schmitz, C1
Durka, S; Hueber, A; Weller, M1
Jordan, MA; Wilson, L1
Capen, CC; Gröne, A; Rosol, TJ; Weckmann, MT1
Ebneth, A; Godemann, R; Illenberger, S; Mandelkow, E; Stamer, K; Trinczek, B1
Popov, S; Zakharenko, S1
Gundersen, GG; Mikhailov, A1
Nishimura, Y; Sameni, M; Sloane, BF1
Bornens, M; Chan, PK; Jordan, EG; Olson, MO; Rousselet, A; Zatsepina, OV1
Balczon, R; Schroer, TA; Varden, CE1
Hagen, K; Kong, AN; Mandlekar, S; Roninson, IB; Shtil, AA; Tan, TH; Walter, RJ; Yu, R1
Frackelton, AR; Ravichandran, KS; Stevenson, LE1
Askham, JM; Markham, AF; Meredith, DM; Morrison, EE; Wardleworth, BN1
Boucke, K; Greber, UF; Keller, S; Nakano, MY; Stidwill, RP; Suomalainen, M1
Diamantopoulos, GS; Kreis, TE; Perez, F; Stalder, R1
Goto, J; Hazeki, N; Kanazawa, I; Nakamura, K1
Gallo, G; Letourneau, PC1
Hansson, V; Jahnsen, T; Keryer, G; Landmark, BF; Skålhegg, BS; Taskén, K1
Shaw, MK1
Brinkley, BR; Clark, GD; McNeil, RS; Swann, JW1
Brown, G; Bunce, CM; Johnson, WE; Suniara, RK; Watters, DJ1
Chen, J; Donovan, S; Hong, FD; Nisen, PD; Schneider, N1
Itin, C; Mühlbauer, B; Pfeffer, SR; Ulitzur, N1
Cohen, E; Ophir, I; Shaul, YB1
Leist, M; Nicotera, P; Volbracht, C1
Alonso, DF; Aon, MA; Arregui, C; Farina, HG; Gomez, DE1
Kaverina, I; Krylyshkina, O; Small, JV1
Burridge, K; Liu, BP; Salmon, ED; Waterman-Storer, CM; Worthylake, RA1
Denoulet, P; Desbruyères, E; Eddé, B; Regnard, C1
Kamitsubo, E; Miyazaki, A; Nemoto, SI1
Baas, PW; Cook, C; Ferhat, L; Kuriyama, R1
Chernobelskaya, AA; Grigoriev, IS; Vorobjev, IA1
Inkinen, RI; Järveläinen, HT; Jortikka, MO; Kärner, J; Lammi, MJ; Nelimarkka, LO; Parkkinen, JJ; Tammi, MI1
Alvarez, R; Dong, C; Feng, XH; Goldschmidt-Clermont, PJ; Li, Z1
Compton, HL; Roos, DS; Shaw, MK; Tilney, LG1
Adamo, S; Coletti, D; Molinaro, M; Naro, F; Palleschi, S; Silvestroni, L1
Keith, CH; Kisaalita, WS; Wilson, MT1
Patrick, DL; Webster, DR1
Lee, J; Miyano, T; Moor, RM1
Craig, RW; Domina, AM; Smith, JH1
Carmichael, J; Fogarty, KE; Kidd, JF; Skepper, JN; Thorn, P; Turner, A1
Dannenberg, AJ; Hart, JC; Norton, L; Subbaramaiah, K1
Cho, SK; Choi, SH; Kim, EY; Kim, NH; Lim, JH; Park, SP1
Fujiu, K; Numata, O2
Albertini, DF; Carabatsos, MJ; Combelles, CM; Messinger, SM1
Cherian, SP; Collins, N; Han, EK; Ng, SC; Tahir, SK1
Ballestrem, C; Hinz, B; Imhof, BA; Wehrle-Haller, B1
Cole, R; Rieder, CL1
Benchimol, M; De Souza, W; Granger, BL; Warwood, SJ1
Bowman, PS; Kolodney, MS; Paul, RJ1
Isowa, N; Keshavjee, SH; Liu, M1
Bellamy, AR; Taylor, JA; Xu, A1
Karbowski, M; Nishizawa, Y; Spodnik, JH; Teranishi, M; Usukura, J; Wakabayashi, T; Wozniak, M1
Bornens, M; Gavet, O; Küntziger, T; Manceau, V; Sobel, A1
Hansen, LK; Hu, WS; Tzanakakis, ES1
Frazer, IH; Liu, WJ; Liu, XS; Liu, YH; Qi, YM; Zhao, KN1
Camacho Gomez, JA; Kirschstein, SO; Kittler, L; Neumann, T; Unger, E1
Fernandez, MA; Hamm-Alvarez, SF; Lindberg, J; Ropp, JD1
Hoffman, DB; Howell, BJ; Pearson, CG; Salmon, ED; Yen, TJ1
Crystal, RG; Hogan, SM; Leopold, PL; Seidman, MA; Wendland, RL; Worgall, S1
Giet, R; Prigent, C1
Chan, EK; Dorn, MC; Goldenring, JR; Griner, R; Hales, CM; Hardy, D; Hobdy-Henderson, KC; Kumar, R; Lapierre, LA; Navarre, J1
Blaho, JA; Blouin, A; Kotsakis, A; Pomeranz, LE1
James, DE; Meerloo, T; Molero, JC; Whitehead, JP1
Kucik, DF; Li, J; Zhou, X1
Bevilacqua, A; Calastretti, A; Capaccioli, S; Ceriani, C; Nicolin, A; Viganò, S; Zancai, P1
Berman, E; Cohen, JS; Mardor, Y; Ringel, I; Sterin, M1
Meraldi, P; Nigg, EA1
Gundersen, GG; Lin, SX; Maxfield, FR1
Abadie, B; Berthet, V; Kadi, A; Luis, J; Marvaldi, J; Pichard, V; Rognoni, JB1
Hasegawa, S; Hirashima, N; Nakanishi, M1
Ahn, NG; Galasinski, SC; Goodrich, JA; Resing, KA1
Block, ER; Su, Y; Zharikov, SI1
Bayley, PM; Erent, M; Martin, S; Moisoi, N; Whyte, S1
Blajeski, AL; Kaufmann, SH; Kottke, TJ; Phan, VA1
Armati, PJ; Dekroon, RM1
Agostinis, P; Assefa, Z; De Witte, PA; Merlevede, W; Piette, J; Vandenheede, JR; Vantieghem, A; Xu, Y1
Gallacher, DV; Harmer, AR; Smith, PM1
Adler, G; Algül, H; Beil, M; Schmid, RM; Schneider, G; Tando, Y; Von Weyhern, C; Weber, CK1
Baas, PW; He, Y; Yu, W1
Blagosklonny, MV; Fojo, T; Giannakakou, P; Greber, UF; Nakano, M; Nicolaou, KC; O'Brate, A; Yu, J1
Ludueña, RF; Xu, K1
Grabeklis, SA; Gulak, PV; Kireev, II; Le Guellec, K; Poliakov, VIu; Timirbulatova, ER; Uzbekov, RE1
Cunningham, JJ; Mooney, DJ; Pillemer, BB; Putnam, AJ1
Liu, JL; Sung, LY; Tian, XC; Yang, X1
Goldstein, B; Lee, JY1
Fällman, M; Holmfeldt, P; McGee, K1
Andersson, S; Arber, F; da Costa, SR; Hamm-Alvarez, S; Okamoto, C1
Garg, R; Mitsopoulos, C; Morris, JD; Ridley, AJ; Zihni, C1
Chudinova, EM; Ivanov, PA; Nadezhdina, ES2
Cole, RW; Hauf, S; Heckel, A; LaTerra, S; Peters, JM; Rieder, CL; Schnapp, G; van Meel, J; Walter, R; Zimmer, C1
Chuckowree, JA; Vickers, JC1
Baek, KH; Cho, JH; Choi, YH; Lee, CW; McKeon, F; Shin, HJ; Sung, YC; Yoo, JK1
Carmena, M; Carvalho, A; Earnshaw, WC; Sambade, C; Wheatley, SP1
Maeno, K; Masuda, A; Nakagawa, T; Saito, H; Takahashi, T1
Giehl, K; Goppelt-Struebe, M; Graness, A; Iwanciw, D; Ott, C1
Reynolds, AB; Roczniak-Ferguson, A1
Burnette, JO; Dorn, MC; Goldenring, JR; Lapierre, LA; Navarre, J; Zimmerman, CF1
Eichenmüller, B; Everley, P; Himes, RH; Kedersha, N; Lang, J; Solovyeva, E; Suprenant, KA1
Benchimol, M; Madeiro da Costa, RF1
Häkkinen, L; Koivisto, L; Larjava, H; Matsumoto, K; McCulloch, CA; Yamada, KM1
Dong, C; Goldschmidt-Clermont, PJ; Zhu, S1
Beisson, J; Bergdoll, M; Dupuis-Williams, P; Forquignon, F; Klotz, C; Koll, F; Ruiz, F1
Andrews, PD; Duncan, K; Morrice, N; Ovechkina, Y; Swedlow, JR; Wagenbach, M; Wordeman, L1
Cheville, JC; Lingle, WL; Mitchell, RF; Mora, GR; Olivier, KR; Tindall, DJ1
Hou, Y; Li, SW; Li, YH; Ma, W; Meng, XQ; Sun, QY; Sun, XF; Wang, WH; Zhang, D1
Asnaghi, L; Bevilacqua, A; Calastretti, A; Canti, G; Capaccioli, S; D'Agnano, I; Delia, D; Gatti, G; Nicolin, A1
Chan, G; Dowling, ML; Harris, E; Kao, GD; Keutmann, MK; Lee, EA1
Olins, AL; Olins, DE1
Hou, Y; Li, M; Li, SW; Li, YH; Ma, W; Sun, QY; Wang, WH; Zhang, D1
Li, L; Sherwood, J; Swartz, DR; Zhang, D1
Ivannikov, MV; Johansson, M; Mironov, SL1
Hallmann, A; Kedzior, J; Kurono, C; Majczak, A; Masaoka, M; Myśliwski, A; Niemczyk, E; Soji, T; Spodnik, JH; Trzonkowski, P; Wakabayashi, T1
Arce, CA; Barra, HS; Casale, CH; Previtali, G; Serafino, JJ1
Bement, WM; Benink, HA1
Modrianský, M; Vrba, J1
Nakayama, Y; Yamaguchi, N1
Dowling, M; Harris, E; Kao, GD; Keutmann, MK; Kim, M; Voong, KR1
Davis, HW; Edwards, JD; Reid, MD; Roy-Chaudhury, P; VandenBerg, E1
Dangi, S; Shapiro, P1
Scaife, RM1
Feng, J; Jiang, H; Jiang, Q; Liu, W; Ren, Y1
Ambrose, HE; Beswick, RW; Wagner, SD1
Baff, W; Dowling, ML; Kao, GD; Kim, M; Liu, F; Murphy, K; Parker, SE1
Botta, A; Marzin, D; Orsière, T; Pallen, C; Steiblen, G1
Bozko, P; Larsen, AK; Sabisz, M; Skladanowski, A1
Amano, A; Inaba, H; Nakagawa, I; Nakanishi, Y; Tsuda, K; Umebayashi, K; Yoshimori, T1
Gorbsky, GJ; Yamada, HY1
Fallon, JR; Taylor, AB1
Ren, X; Weisblat, DA1
Dvorák, Z; Modrianský, M1
Ansar, S; Bean, J; Michaelis, ML; Seyb, KI1
Hiratsuka, M; Inoue, T; Ito, H; Katoh, M; Kishimoto, I; Nakano, S; Osaki, M; Oshimura, M; Yamada, H; Yamaguchi, S1
Eves, EM; Klein, UR; Naik, K; Rosner, MR; Shapiro, P; Trakul, N1
Feng, Y; Li, W; Xia, JT1
Bauer, NG; Richter-Landsberg, C1
Allday, MJ; Anderton, E; Leao, M; Meekings, K; Wade, M1
Kogo, Y; Ohishi, I; Uematsu, Y1
Braunhut, SJ; Marx, KA; McIntosh, D; Montrone, A; Zhou, T1
Clarke, A; Dikovskaya, D; Jamieson, TJ; Kroboth, K; Meniel, V; Näthke, IS; Newton, IP; Oakley, A; Sansom, O; Schiffmann, D1
Chen, DY; Gao, WX; Hou, Y; Huo, LJ; Liu, K; Liu, XJ; Schatten, H; Sun, QY; Wang, CM; Wang, Q; Xiong, B; Yu, LZ; Zhong, ZS1
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Akhmanova, A; Borisy, GG; Chaga, OY; Komarova, YA; Schober, JM1
Baas, PW; Bertrand, L; de Chadarévian, JP; Dráber, P; Dráberová, E; Katsetos, CD; Legido, A; Nissanov, J; Reddy, G; Smejkalová, B1
Chen, J; Draviam, VM; Elledge, SJ; Hannon, GJ; Harper, JW; Liang, A; Nalepa, G; Sorger, PK; Sowa, ME; Stegmeier, F1
Dai, W; Duan, Q; Guo, TB; Lu, L; Lu, ZY; Ruan, Q; Wang, XX; Xu, GT; Xu, M; Yang, YL; Zhang, JW1
Clément, N; Gigout, L; Hirosue, S; Linden, RM; Nonnenmacher, M; Senn, K; Weber, T1
Dixit, A; Kitagawa, K; Niikura, Y; Perkins, G; Scott, R1
Meyer, TF; Rudel, T; Wang, JA1
Bradke, F; Enes, J; Ertürk, A; Hellal, F1
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Blum, M; Mihatsch, J; Möller, W; Rösner, H; Wassermann, T1
Alvanou, A; Angelov, DN; Angelova, SK; Grosheva, M; Guntinas-Lichius, O; Kuerten, S; Pavlov, S; Sinis, N; Skouras, E; Streppel, M1
Sluder, G; Uetake, Y1
Dewhurst, S; Rodrigo, WW; Sapinoro, R; Schlesinger, JJ; Volcy, K1
Bradke, F; Neukirchen, D; Witte, H1
Chernyak, BV; Dolgikh, DA; Domnina, LV; Gasparian, ME; Ivanova, OY; Izyumov, DS; Lomakin, AY; Pletjushkina, OY; Popova, EN; Yagolovich, AV1
Georgi, A; Hamprecht, F; Kirchner, M; Kirschner, MW; Parker, K; Springer, M; Steen, H; Steen, JA1
McNeely, SC; Miller, HL; States, JC; Taylor, BF1
McNeely, SC; States, JC; Taylor, BF1
Nakaya, Y; Sheng, G; Sukowati, EW; Wu, Y1
Ai, JS; Chen, DY; Li, S; Ouyang, YC; Sun, QY; Sun, SC; Xiong, B; Yin, S1
Brito, DA; Rieder, CL; Yang, Z1
Brito, DA; Rieder, CL1
Chabalier-Taste, C; Dozier, C; Larminat, F; Racca, C1
Conklin, DS; Hergert, P; Khodjakov, A; Kourtidis, A; Loncarek, J; O'Connell, CB1
Jou, I; Kim, HY; Park, JY; Park, SM1
Firestein, BL; Gu, J; Zheng, JQ1
Arkhipov, SN; Baratt, A; Maly, IV1
Colombaioni, L; Voccoli, V1
Cowley, DO; Lu, L; O'Quinn, R; Oliver, TG; Salmon, ED; Schliekelman, M; Van Dyke, T1
Johansson, C; Lundkvist, A; Mirazimi, A; Simon, M1
Chakravarty, A; Ecsedy, JA; Hoar, K; Wysong, DR1
Dean, D; Hemmer, JD; Laberge, M; Nagatomi, J; Vertegel, AA; Wood, ST1
Bastians, H; Ertych, N; Kienitz, A; Schneider, V; Stolz, A; Vogel, C; Yu, H1
Oka, S; Sakaushi, S; Senda-Murata, K; Sugimoto, K1
Hendricks, M; Jesuthasan, S1
Kastrinaki, MC; Papadaki, HA; Polioudaki, H; Theodoropoulos, PA1
Bekier, ME; Fischbach, R; Lee, J; Taylor, WR1
Kanada, M; Nagasaki, A; Uyeda, TQ1
Baillet, A; Cantaloube, I; Couloubaly, S; Fourniat, C; Giustiniani, J; Paul, JL; Pourci, ML; Poüs, C1
Brito, DA; Kenny, AE; Rieder, CL; Yang, Z1
McGee, KM; Rosenblatt, J; Slattum, G1
Duits, MH; Li, Y; Vanapalli, SA1
Carpenter, AE; Kim, S; Mitchison, TJ; Orth, JD; Rudnicki, S; Shamu, CE; Tsui, M; Xie, T1
Li, M; Li, S; Lin, SL; Schatten, H; Sun, QY; Wei, L; Xiong, B; Yin, S; Yuan, J1
Mattaj, IW; Platani, M; Posch, M; Santarella-Mellwig, R; Swedlow, JR; Walczak, R1
Choi, IK; Gao, R; Kaul, SC; Kaur, K; Kim, I; Morrow, G; Ryu, J; Tanguay, RM; Wadhwa, R; Yun, CO1
Irimia, D; Toner, M1
Duarte, M; Lepault, J; Martin, D; Poncet, D1
Ballestrem, C; Goldyn, AM; Kaiser, P; Kemkemer, R; Spatz, JP1
Hou, Y; Li, M; Lin, SL; Ouyang, YC; Schatten, H; Sun, QY; Zhu, JL1
Hou, Y; Li, M; Ouyang, YC; Qi, ST; Schatten, H; Sun, QY; Tong, JS; Wei, L; Xu, BZ; Yuan, J1
Goshima, Y; Gotoh, T; Hida, T; Ichikawa, Y; Kamiya, Y; Kuraoka, S; Shiozawa, T; Takeshita, S; Usui, H; Yamashita, N1
Amaiden, MR; Arce, CA; Campetelli, AN; Casale, CH; Monesterolo, NE; Previtali, G; Rivelli, JF; Santander, VS1
Fadlalla, K; Samuel, T; Turner, T; Yehualaeshet, TE1
Liu, L; McKeehan, WL; Nguyen, S; Xie, R1
Seemann, J; Wei, JH1
Lemasters, JJ; Maldonado, EN; Mullins, MR; Patnaik, J1
Carbonaro, M; Giannakakou, P; O'Brate, A1
Apontes, P; Blagosklonny, MV; Demidenko, ZN; Leontieva, OV; Li, F1
Leblanc, J; Li, R; Liu, XJ; Ma, C; McKee, D; Sun, QY; Wang, ZB; Zhang, X1
Mooberry, SL; Risinger, AL1
Balmanno, K; Clark, J; Cook, SJ; Gilley, R; Lochhead, PA; Oxley, D1
Hou, Y; Ouyang, YC; Qi, ST; Schatten, H; Sun, QY; Wang, YP; Wang, ZB; Zhu, J1
Hasegawa, Y; Ito, S; Kondo, M; Morioka, M; Naruse, K; Parameswaran, H; Sokabe, M; Suki, B1
Firestein, BL; Tseng, CY1
Mac Fhearraigh, S; Mc Gee, MM1
Cincinelli, R; De Cesare, M; Nannei, R; Pisano, C; Zaffaroni, N; Zuco, V; Zunino, F1
Bugnard, E; Mehta, A; Mousavi, K; Ralston, E; Reid, E; Sartorelli, V; Zaal, KJ; Zhang, T1
Chen, CH; Chen, Q; Li, L; Wang, Y; Xu, SC; Yu, ZP; Zhang, L; Zhang, YW; Zhong, M; Zhou, Z1
Hidaka, M; Hirose, K; Horiguchi, T; Kiyota, H; Koga, T; Shi, QW; Uchida, T1
Carney, BK; Caruso Silva, V; Cassimeris, L1
Burke, DJ; Demirel, PB; Matson, DR; Stukenberg, PT1
Demopoulos, NA; Stephanou, G; Zacharaki, P1
Cavalca, V; Colli, S; Crisci, M; Eligini, S; Songia, P; Tremoli, E1
Amaiden, MR; Arce, CA; Campetelli, AN; Casale, CH; Hope, SI; Monesterolo, NE; Pie, J; Santander, VS; Vatta, MS1
Courageot, S; Curmi, PA; Dalard, C; Delga, S; Fassier, C; Hazan, J; Job, D; Lefèvre, J; Mailly, P; Melki, J; Peris, L; Roblot, N; Tarrade, A1
Arcangeletti, MC; Calderaro, A; Chezzi, C; De Conto, F; Di Lonardo, E; Medici, MC1
Aminoff, MJ; Boban, D; Brandt, R; Brühmann, J; Cabin, DE; Christine, CW; Epling, L; Fanara, P; Hellerstein, MK; Husted, KH; Killian, M; Killion, S; Kohlstaedt, LA; Liu, S; Liu, VM; Nussbaum, RL; Peterson, J; Price, RW; Protasio, JC; Riiff, T; Sinclair, E; Wong, PY1
Hao, J; Liu, GY; Wang, DH; Xu, YF; Yu, J; Yuan, BB1
Kaplan, DL; Naumova, EN; Spedden, E; Staii, C; White, JD1
Allart, S; Gaits-Iacovoni, F; Gratacap, MP; Payrastre, B; Severin, S1
Cai, Y; Hu, M; Jiang, F; Liu, C; Liu, Q; Luo, J; Luo, M; Shi, Q; Song, P; Tang, M; Weng, Y; Yang, D; Zhan, X; Zhang, F; Zhang, Y; Zhou, L; Zuo, G1
Chen, L; Gao, C; Huang, H; Jiang, ZZ; Lin, F; Qi, ST; Song, YL; Sun, QY; Wang, ZW; Xing, FQ; Yang, SW; Zhu, JL1
Cheng, PP; Ding, L; He, XQ; Huang, X; Liu, Y; Ma, PF; Pan, R; Qi, ZQ; Shen, YT; Wang, HL; Xu, L; Zhang, CH1
Evan, GI; MacFhearraigh, S; Mc Gee, MM; O'Donovan, DS; Swigart, LB; Whitfield, J1
Castro, C; de León, DC; Gallardo, D; Herrera, LA; López, A; Mendoza, J; Mohar, A; Morales, F; Oñate, LF; Perez, D; Prada, D; Santibáñez, M1
Biankin, AV; Caldon, CE; Clark, SJ; Cowley, MJ; Gallego-Ortega, D; Gee, JM; McCloy, RA; Musgrove, EA; Nicholson, RI; Ormandy, CJ; Print, CG; Sergio, CM; Stone, A; Valdes-Mora, F1
Chen, JK; Chung, AH; Hammer, JA; Kapoor, TM; Wu, X; Yi, J1
Chen, Y; Chong, R; Ding, SJ; Dong, J; Liu, M; Yang, S; Zhang, L1
Hayashi, H; Katoh, H; Kumazawa, A; Nonaka, D; Saotome, M; Satoh, H; Urushida, T; Watanabe, T1
Chen, C; Chen, Q; Xu, S; Yu, Z; Zhang, L; Zhou, Z1
Beauchemin, M; Bertrand, R; Wang, J1
Gao, Y; Hedstrom, L; Kuang, Y; Long, MJ; Shi, J; Xu, B; Xu, C; Zhou, J1
Ti, Y; Wang, R; Zhao, J; Zhou, L1
Chen, L; Ge, ZJ; Ouyang, YC; Sun, QY; Sun, T; Sun, YP; Wang, ZB1
Chumduri, C; Daniel, PT; Gillissen, B; Milojkovic, A; Müller, A; Overkamp, T; Pott, C; Richter, A1
Chang, WL; Chen, CS; Guh, JH; Yu, CC1
Moore, P; Viegas, J1
Britton, S; Douglas, P; Lees-Miller, SP; Morrice, N; Trinkle-Mulcahy, L; Ye, R1
Brakenhoff, RH; de Lange, J; de Menezes, RX; de Winter, JP; Faramarz, A; King, RW; Oostra, AB; Rockx, DA; Rooimans, MA; van Beusechem, VW; van der Meulen, IH; Wolthuis, RMF1
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Hou, Y; Liang, QX; Ma, XS; Meng, TG; Ouyang, YC; Quan, S; Schatten, H; Sun, QY; Xu, ZY; Yi, ZY; Zhang, T1
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Reviews

3 review(s) available for nocodazole and paclitaxel

ArticleYear
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles

2019
Development and functions of the cytoskeleton during ciliogenesis in metazoa.
    Biology of the cell, 1988, Volume: 63, Issue:2

    Topics: Alkaloids; Animals; Benzimidazoles; Centrioles; Cilia; Colchicine; Cytochalasin D; Cytochalasins; Cytoskeleton; Diazepam; Epithelium; Morphogenesis; Nocodazole; Paclitaxel; Quail

1988
Microtubule disruptors and their interaction with biotransformation enzymes.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2005, Volume: 149, Issue:2

    Topics: Antimitotic Agents; Biotransformation; Colchicine; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Microtubules; Nocodazole; Paclitaxel; Receptors, Aryl Hydrocarbon; Receptors, Glucocorticoid; Signal Transduction; Vinblastine; Vincristine

2005

Other Studies

463 other study(ies) available for nocodazole and paclitaxel

ArticleYear
Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents.
    Journal of medicinal chemistry, 2001, Dec-20, Volume: 44, Issue:26

    Topics: Allantois; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Biopolymers; Cattle; Chorion; Drug Screening Assays, Antitumor; G2 Phase; GTP Phosphohydrolases; Humans; In Vitro Techniques; Indoles; Melanoma; Mice; Mice, Nude; Mitosis; Structure-Activity Relationship; Transplantation, Heterologous; Tubulin; Tumor Cells, Cultured

2001
Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Journal of medicinal chemistry, 2003, Jul-17, Volume: 46, Issue:15

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Biopolymers; Blotting, Western; Cell Cycle; Cell Survival; Drug Screening Assays, Antitumor; Humans; K562 Cells; Microscopy, Electron; Structure-Activity Relationship; Tubulin

2003
Cytotoxic constituents of Aspergillus terreus from the rhizosphere of Opuntia versicolor of the Sonoran Desert.
    Journal of natural products, 2003, Volume: 66, Issue:12

    Topics: Antineoplastic Agents; Arizona; Aspergillus; Cell Cycle; Cell Line, Tumor; Cyclopentanes; Desert Climate; Drug Screening Assays, Antitumor; Humans; Indoles; Molecular Structure; Nervous System Neoplasms; Nuclear Magnetic Resonance, Biomolecular; Opuntia; Stereoisomerism

2003
9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Proliferation; Cell Survival; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Humans; Inhibitory Concentration 50; K562 Cells; Leukemia P388; Mice; Molecular Structure; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Anthracenes; Cell Cycle; Cell Line, Tumor; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Naphthalenes; Nocodazole; Podophyllotoxin; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators

2007
10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Journal of medicinal chemistry, 2009, Mar-12, Volume: 52, Issue:5

    Topics: Anthracenes; Binding, Competitive; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; G2 Phase; Humans; Protein Binding; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a new scaffold that provides rapid access to antimicrotubule agents: synthesis and evaluation of antiproliferative activity against select cancer cell lines.
    Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8

    Topics: Acrylamides; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; G2 Phase; Humans; Microtubules; Oxazoles; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators

2010
Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:8

    Topics: Anthracenes; Antineoplastic Agents; Benzylidene Compounds; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Protein Multimerization; Protein Structure, Quaternary; Tubulin

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Journal of medicinal chemistry, 2011, Jun-23, Volume: 54, Issue:12

    Topics: Antineoplastic Agents; Biopolymers; Cell Cycle; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Organ Specificity; Oxazines; Phenothiazines; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2011
Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Bioorganic & medicinal chemistry, 2011, Jul-15, Volume: 19, Issue:14

    Topics: Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Microtubules; Molecular Structure; Schiff Bases; Stereoisomerism; Structure-Activity Relationship; Tubulin

2011
Synthesis of terphenyl benzimidazoles as tubulin polymerization inhibitors.
    European journal of medicinal chemistry, 2012, Volume: 50

    Topics: Benzimidazoles; Blotting, Western; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

2012
Identification of selective tubulin inhibitors as potential anti-trypanosomal agents.
    Bioorganic & medicinal chemistry letters, 2012, Sep-01, Volume: 22, Issue:17

    Topics: Amino Acid Sequence; Animals; Cattle; Cell Proliferation; Cells, Cultured; Fibroblasts; Humans; Models, Molecular; Molecular Sequence Data; Structural Homology, Protein; Sulfonamides; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tubulin; Tubulin Modulators

2012
A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization.
    Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Biphenyl Compounds; Cytoskeletal Proteins; Drug Resistance, Multiple; Enterococcus; Guanidines; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Polymerization; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin Resistance

2012
3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents.
    Bioorganic & medicinal chemistry, 2012, Dec-15, Volume: 20, Issue:24

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cytoskeletal Proteins; Enterococcus faecalis; HEK293 Cells; Humans; Isoquinolines; Molecular Targeted Therapy; Staphylococcus aureus

2012
Design and synthesis of biaryl aryl stilbenes/ethylenes as antimicrotubule agents.
    European journal of medicinal chemistry, 2013, Volume: 60

    Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Ethylenes; HeLa Cells; Humans; Models, Molecular; Molecular Structure; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured

2013
Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents.
    Bioorganic & medicinal chemistry letters, 2013, Apr-01, Volume: 23, Issue:7

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cytoskeletal Proteins; Enterococcus faecalis; Microbial Sensitivity Tests; Molecular Structure; Naphthalenes; Polymerization; Staphylococcus aureus

2013
Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
    Journal of medicinal chemistry, 2013, Jul-11, Volume: 56, Issue:13

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Blood-Brain Barrier; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Drug Design; Drug Resistance, Neoplasm; HCT116 Cells; Humans; K562 Cells; MCF-7 Cells; Mice; Mice, Nude; Microtubules; Neoplasms; Polymerization; Sulfonamides; Tubulin; Tumor Burden; Xenograft Model Antitumor Assays

2013
β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand.
    Journal of medicinal chemistry, 2014, Nov-26, Volume: 57, Issue:22

    Topics: Apoptosis; beta-Lactams; Cell Division; Chemistry, Pharmaceutical; Computer Simulation; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Estrogen Receptor beta; Estrogens; G2 Phase; Humans; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Ligands; MCF-7 Cells; Models, Molecular; Myeloid Cell Leukemia Sequence 1 Protein; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Software; Tetrazolium Salts; Thiazoles; Tubulin

2014
Progress Toward the Development of Noscapine and Derivatives as Anticancer Agents.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Neoplasms; Noscapine

2015
Synthesis and evaluation of benzosuberone embedded with 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole moieties as new potential anti proliferative agents.
    Bioorganic & medicinal chemistry letters, 2015, Volume: 25, Issue:10

    Topics: Antineoplastic Agents; Azoles; Cell Line, Tumor; Cell Proliferation; Coumarins; Humans; Molecular Structure; Oxadiazoles; Thiadiazoles; Triazoles

2015
Synthesis and biological evaluation of thiabendazole derivatives as anti-angiogenesis and vascular disrupting agents.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Angiogenesis Inhibitors; Anthelmintics; Cell Proliferation; Drug Repositioning; HCT116 Cells; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Structure-Activity Relationship; Thiabendazole; Tubulin; Tubulin Modulators

2015
Triphenylphosphonium Cations of the Diterpenoid Isosteviol: Synthesis and Antimitotic Activity in a Sea Urchin Embryo Model.
    Journal of natural products, 2015, Jun-26, Volume: 78, Issue:6

    Topics: Animals; Antimitotic Agents; Antineoplastic Agents; Cations; Disease Models, Animal; Diterpenes; Diterpenes, Kaurane; Humans; Mediterranean Sea; Mitochondria; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organophosphorus Compounds; Sea Urchins; Structure-Activity Relationship

2015
Design and synthesis of a C7-aryl piperlongumine derivative with potent antimicrotubule and mutant p53-reactivating properties.
    European journal of medicinal chemistry, 2016, Jan-01, Volume: 107

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Chemistry Techniques, Synthetic; Dioxolanes; Drug Design; Female; Genes, Tumor Suppressor; Glutathione; Humans; Microtubules; Mutation; Reactive Oxygen Species; Stilbenes; Tumor Suppressor Protein p53

2016
Synthesis and bio-evaluation of novel quinolino-stilbene derivatives as potential anticancer agents.
    Bioorganic & medicinal chemistry, 2015, Dec-15, Volume: 23, Issue:24

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Neoplasms; Quinolines; Stilbenes; Tubulin; Tubulin Modulators

2015
Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent in Vitro and in Vivo Anticancer Activities.
    Journal of medicinal chemistry, 2016, Jan-14, Volume: 59, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Marine Toxins; Mice; Mice, Nude; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Xanthines

2016
Synthesis and biological evaluation of quinazolin-4(3H)-one derivatives bearing dithiocarbamate side chain at C2-position as potential antitumor agents.
    European journal of medicinal chemistry, 2016, Jan-27, Volume: 108

    Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Quinazolinones; Structure-Activity Relationship; Thiocarbamates

2016
Synthesis, anti-cancer evaluation of benzenesulfonamide derivatives as potent tubulin-targeting agents.
    European journal of medicinal chemistry, 2016, Oct-21, Volume: 122

    Topics: Antineoplastic Agents; Apoptosis; Benzenesulfonamides; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Protein Multimerization; Protein Structure, Quaternary; Solubility; Structure-Activity Relationship; Sulfonamides; Tubulin; Tubulin Modulators; Water

2016
Piperlongumine (piplartine) and analogues: Antiproliferative microtubule-destabilising agents.
    European journal of medicinal chemistry, 2017, Jan-05, Volume: 125

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Dioxolanes; Female; Humans; MCF-7 Cells; Microtubules; Models, Molecular; Piperidones; Reactive Oxygen Species; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2017
Development and Biological Evaluation of a Photoactivatable Small Molecule Microtubule-Targeting Agent.
    ACS medicinal chemistry letters, 2017, Apr-13, Volume: 8, Issue:4

    Topics:

2017
Design and synthesis of 1,2,3-triazolo linked benzo[d]imidazo[2,1-b]thiazole conjugates as tubulin polymerization inhibitors.
    Bioorganic & medicinal chemistry, 2017, 07-01, Volume: 25, Issue:13

    Topics: Antineoplastic Agents; Cell Cycle Checkpoints; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Imidazoles; MCF-7 Cells; Molecular Docking Simulation; Molecular Structure; Polymerization; Structure-Activity Relationship; Thiazoles; Triazoles; Tubulin

2017
Novel Gomisin B analogues as potential cytotoxic agents: Design, synthesis, biological evaluation and docking studies.
    European journal of medicinal chemistry, 2017, Oct-20, Volume: 139

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooctanes; Cytotoxins; Dioxoles; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Lignans; Molecular Docking Simulation; Molecular Structure; Polycyclic Compounds; Schisandra; Structure-Activity Relationship

2017
Synthesis and anticancer activity of novel water soluble benzimidazole carbamates.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Animals; Antineoplastic Agents; Benzimidazoles; Carbamates; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Male; Mice; Molecular Docking Simulation; Molecular Structure; Neoplasms, Experimental; Solubility; Structure-Activity Relationship; Tumor Cells, Cultured; Water

2018
Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position.
    European journal of medicinal chemistry, 2018, Jun-25, Volume: 154

    Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Thiocarbamates; Tumor Cells, Cultured

2018
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents.
    European journal of medicinal chemistry, 2019, Jan-15, Volume: 162

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Humans; Microtubules; Molecular Structure; Oxazepines; Structure-Activity Relationship

2019
Synthesis and biological evaluation of cis-restrained carbocyclic combretastatin A-4 analogs: Influence of the ring size and saturation on cytotoxic properties.
    Bioorganic & medicinal chemistry, 2019, 10-01, Volume: 27, Issue:19

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Humans; Molecular Docking Simulation; Molecular Structure; Protein Binding; Stilbenes; Tubulin; Tubulin Modulators

2019
4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin.
    European journal of medicinal chemistry, 2019, Nov-01, Volume: 181

    Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Cell Proliferation; Colchicine; Drug Resistance, Neoplasm; Humans; Molecular Docking Simulation; Neoplasms; Quinolones; Tubulin; Tubulin Modulators

2019
Identification of 2,6-Disubstituted 3
    Journal of medicinal chemistry, 2019, 10-24, Volume: 62, Issue:20

    Topics: Binding Sites; Cell Differentiation; Cell Proliferation; Drug Design; Dysferlin; Hep G2 Cells; Humans; Imidazoles; Induced Pluripotent Stem Cells; Molecular Docking Simulation; Muscular Dystrophies, Limb-Girdle; Myocytes, Cardiac; MyoD Protein; Protein Structure, Tertiary; Pyridines; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2019
Chalcone derivatives targeting mitosis: synthesis, evaluation of antitumor activity and lipophilicity.
    European journal of medicinal chemistry, 2019, Dec-15, Volume: 184

    Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Chalcone; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured

2019
Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cells.
    Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1

    Topics: Cell Line, Tumor; Centrosome; Diterpenes; Dose-Response Relationship, Drug; Humans; Kinesins; Mitosis; Molecular Structure; Schizosaccharomyces; Spindle Apparatus; Structure-Activity Relationship

2020
Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors.
    European journal of medicinal chemistry, 2020, Apr-15, Volume: 192

    Topics: Dose-Response Relationship, Drug; Halogenation; HCT116 Cells; Humans; Molecular Structure; Polymerization; Quinolones; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2020
Cardiostimulatory and antiarrhythmic activity of tubulin-binding agents.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Feb-15, Volume: 89, Issue:4

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Doxorubicin; Etoposide; Heart Rate; In Vitro Techniques; Microtubules; Myocardial Contraction; Nocodazole; Paclitaxel; Podophyllotoxin; Rats; Tubulin; Vinca Alkaloids

1992
Accumulation of a microtubule-binding protein, pp170, at desmosomal plaques.
    The Journal of cell biology, 1992, Volume: 117, Issue:4

    Topics: Alkaloids; Animals; Cell Compartmentation; Cell Polarity; Cells, Cultured; Desmosomes; Dogs; Fluorescent Antibody Technique; Humans; Immunohistochemistry; In Vitro Techniques; Microtubule-Associated Proteins; Microtubules; Nocodazole; Paclitaxel; Phosphoproteins; Protein Binding; Vinblastine

1992
Gonocytes of male rats resume migratory activity postnatally.
    European journal of cell biology, 1992, Volume: 59, Issue:1

    Topics: Animals; Brefeldin A; Cell Movement; Cyclopentanes; Fluorescent Dyes; Germ Cells; Golgi Apparatus; Male; Monensin; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Testis

1992
Tyrosinated and detyrosinated microtubules in axonal processes of cerebellar macroneurons grown in culture.
    Journal of neuroscience research, 1991, Volume: 28, Issue:2

    Topics: Alkaloids; Animals; Axons; Cells, Cultured; Cerebellum; Immunohistochemistry; Microtubules; Neurons; Nocodazole; Paclitaxel; Tubulin; Tyrosine

1991
Cytoskeleton of intestinal goblet cells: role of microtubules in baseline secretion.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 1

    Topics: Alkaloids; Animals; Cell Membrane; Colon; Cytoplasmic Granules; Cytoskeleton; Female; Glucosamine; Intestinal Mucosa; Microscopy, Electron; Microtubules; Nocodazole; Organ Culture Techniques; Paclitaxel; Rabbits

1991
Identification of a minus end-specific microtubule-associated protein located at the mitotic poles in cultured mammalian cells.
    European journal of cell biology, 1991, Volume: 54, Issue:2

    Topics: Alkaloids; Animals; Autoantibodies; Brain; Cell Line; Cricetinae; Cricetulus; Dimethyl Sulfoxide; HeLa Cells; Microscopy, Fluorescence; Microscopy, Immunoelectron; Microtubule-Associated Proteins; Microtubules; Mitosis; Nocodazole; Paclitaxel; Sodium Chloride; Spindle Apparatus; Tosyllysine Chloromethyl Ketone

1991
Binding of pp170 to microtubules is regulated by phosphorylation.
    The Journal of biological chemistry, 1991, Sep-15, Volume: 266, Issue:26

    Topics: Adenosine Triphosphate; Alkaloids; Chromatography, Affinity; HeLa Cells; Humans; Microtubule-Associated Proteins; Microtubules; Nocodazole; Paclitaxel; Phosphorylation; Polymers; Precipitin Tests; Tubulin

1991
Substrate-bound factors stimulate engorgement of growth cone lamellipodia during neurite elongation.
    Cell motility and the cytoskeleton, 1991, Volume: 19, Issue:4

    Topics: Actin Cytoskeleton; Alkaloids; Animals; Aplysia; Cells, Cultured; Culture Media; Cytochalasin B; Demecolcine; Hemolymph; Image Processing, Computer-Assisted; Microscopy; Microtubules; Neurites; Nocodazole; Paclitaxel; Polylysine; Videotape Recording

1991
Studies on the ejection properties of asters: astral microtubule turnover influences the oscillatory behavior and positioning of mono-oriented chromosomes.
    Journal of cell science, 1991, Volume: 99 ( Pt 4)

    Topics: Alkaloids; Animals; Cells, Cultured; Chromosomes; Demecolcine; Microtubules; Nocodazole; Paclitaxel; Salamandridae; Spindle Apparatus

1991
Cell attachment and neurite stability in NG108-15 cells: what is the role of microtubules?
    Brain research. Developmental brain research, 1991, Feb-22, Volume: 58, Issue:2

    Topics: Adenosine; Alkaloids; Axons; Cell Adhesion; Cell Line; Deoxyadenosines; Hybrid Cells; Immunohistochemistry; Microtubules; Nerve Tissue; Neurons; Nocodazole; Paclitaxel; Staining and Labeling; Thionucleosides; Trypsin; Tubulin

1991
Identification of a novel nucleotide-sensitive microtubule-binding protein in HeLa cells.
    The Journal of cell biology, 1990, Volume: 110, Issue:5

    Topics: Adenosine Triphosphate; Alkaloids; Antibodies; Fluorescent Antibody Technique; Guanosine Triphosphate; HeLa Cells; Humans; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Molecular Weight; Nocodazole; Paclitaxel; Protein Binding; Vinblastine

1990
Blood platelet formation in vitro. The role of the cytoskeleton in megakaryocyte fragmentation.
    Journal of cell science, 1990, Volume: 97 ( Pt 1)

    Topics: Actins; Alkaloids; Animals; Blood Platelets; Cell Differentiation; Cells, Cultured; Cytochalasin D; Cytoskeleton; Fluorescent Antibody Technique; Guinea Pigs; Megakaryocytes; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel

1990
Microtubule perturbation inhibits intracellular transport of an apical membrane glycoprotein in a substrate-dependent manner in polarized Madin-Darby canine kidney epithelial cells.
    Cell regulation, 1990, Volume: 1, Issue:12

    Topics: Alkaloids; Animals; Biological Transport; Blotting, Western; Cell Division; Cell Membrane; Dogs; Epithelium; Fluorescent Antibody Technique; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Membrane Glycoproteins; Microtubules; Nocodazole; Paclitaxel; Statistics as Topic; Viral Envelope Proteins

1990
Neuritic transport of herpes simplex virus in rat sensory neurons in vitro. Effects of substances interacting with microtubular function and axonal flow [nocodazole, taxol and erythro-9-3-(2-hydroxynonyl)adenine].
    The Journal of general virology, 1986, Volume: 67 ( Pt 9)

    Topics: Adenine; Alkaloids; Animals; Axonal Transport; Axons; Benzimidazoles; Cells, Cultured; Lectins; Microtubules; Neurons, Afferent; Nocodazole; Paclitaxel; Rats; Simplexvirus; Virus Replication; Wheat Germ Agglutinins

1986
Effects of dimethylsulfoxide (DMSO), nocodazole, and taxol on mast cell histamine secretion.
    Acta pharmacologica et toxicologica, 1986, Volume: 59, Issue:3

    Topics: Alkaloids; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzimidazoles; Dimethyl Sulfoxide; Histamine Release; Immunochemistry; In Vitro Techniques; Male; Mast Cells; Microtubules; Nocodazole; Paclitaxel; Rats; Rats, Inbred Strains

1986
Construction of the endoplasmic reticulum.
    The Journal of cell biology, 1989, Volume: 109, Issue:5

    Topics: Actins; Alkaloids; Animals; Carbocyanines; Cell Line; Cycloheximide; Cytochalasin B; Endoplasmic Reticulum; Fluorescent Antibody Technique; Fluorescent Dyes; Intermediate Filaments; Microtubules; Nocodazole; Paclitaxel; Staining and Labeling

1989
Fibroblast contractility and actin organization are stimulated by microtubule inhibitors.
    Journal of cell science, 1989, Volume: 93 ( Pt 2)

    Topics: 1-Methyl-3-isobutylxanthine; Actins; Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Cell Movement; Colforsin; Demecolcine; Fibroblasts; Mice; Mice, Inbred Strains; Microscopy, Fluorescence; Microtubules; Nocodazole; Paclitaxel; Photomicrography; Tetradecanoylphorbol Acetate; Vinblastine

1989
Sea urchin primary mesenchyme cells: ingression occurs independent of microtubules.
    Developmental biology, 1989, Volume: 131, Issue:1

    Topics: Alkaloids; Animals; Benzimidazoles; Blastocyst; Colchicine; Culture Techniques; Epithelium; Fluorescent Antibody Technique; Lumicolchicines; Mesoderm; Microtubules; Nocodazole; Paclitaxel; Sea Urchins

1989
The cortical microfilament system of lymphoblasts displays a periodic oscillatory activity in the absence of microtubules: implications for cell polarity.
    The Journal of cell biology, 1989, Volume: 109, Issue:3

    Topics: Actin Cytoskeleton; Actins; Alkaloids; Benzimidazoles; Cell Line; Cell Membrane; Cytoskeleton; Fluorescent Antibody Technique; Humans; Microscopy, Electron; Microscopy, Electron, Scanning; Microtubules; Models, Structural; Myosins; Nocodazole; Paclitaxel; T-Lymphocytes

1989
Regulation of acetylcholinesterase secretion from neuronal cell cultures.--1. Actions of nerve growth factor, cytoskeletal inhibitors and tunicamycin.
    Neuroscience, 1985, Volume: 14, Issue:1

    Topics: Acetylcholinesterase; Alkaloids; Animals; Benzimidazoles; Cell Line; Colchicine; Cytoskeleton; Glucosamine; Isoenzymes; Nerve Growth Factors; Neurons; Nocodazole; Paclitaxel; Pheochromocytoma; Rats; Tunicamycin

1985
Non-spindle microtubule organizing centers in metaphase II-arrested mouse oocytes.
    The Journal of cell biology, 1985, Volume: 101, Issue:5 Pt 1

    Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Benzimidazoles; Female; Fertilization; Metaphase; Mice; Microtubules; Nocodazole; Oocytes; Paclitaxel; Spindle Apparatus

1985
Involvement of microtubules in lipoprotein degradation and utilization for steroidogenesis in cultured rat luteal cells.
    Endocrinology, 1985, Volume: 117, Issue:6

    Topics: Alkaloids; Animals; Benzimidazoles; Cells, Cultured; Colchicine; Corpus Luteum; Deuterium; Dimethyl Sulfoxide; Female; Humans; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lumicolchicines; Microtubules; Nocodazole; Paclitaxel; Podophyllotoxin; Progesterone; Rats; Time Factors; Vinblastine

1985
Spatiotemporal control of functional specification and distribution of spindle microtubules with 13, 14 and 15 protofilaments during mitosis in the ciliate Nyctotherus.
    Journal of cell science, 1985, Volume: 76

    Topics: Alkaloids; Benzimidazoles; Ciliophora; Deuterium; Deuterium Oxide; Microscopy, Electron; Microtubules; Mitosis; Nocodazole; Paclitaxel; Water

1985
Shape changes and chemokinesis of Walker 256 carcinosarcoma cells in response to colchicine, vinblastine, nocodazole and taxol.
    Invasion & metastasis, 1986, Volume: 6, Issue:1

    Topics: Alkaloids; Animals; Antineoplastic Agents; Benzimidazoles; Carcinoma 256, Walker; Cell Movement; Colchicine; Cytochalasin B; Microtubules; Nocodazole; Paclitaxel; Vinblastine

1986
Major loss of junctional coupling during mitosis in early mouse embryos.
    The Journal of cell biology, 1986, Volume: 102, Issue:2

    Topics: Alkaloids; Animals; Benzimidazoles; Cell Communication; Intercellular Junctions; Mice; Mitosis; Nocodazole; Paclitaxel

1986
Centriole size modifications during the cell cycle of the amoebae of the mxyomycete Physarum polycephalum.
    Journal of ultrastructure research, 1985, Volume: 91, Issue:2

    Topics: Alkaloids; Animals; Benzimidazoles; Cell Cycle; Centrioles; Haploidy; Interphase; Microscopy, Electron; Microtubules; Mitosis; Nocodazole; Paclitaxel; Physarum

1985
Numerical evaluation of changes in the cytoplasmic microtubule complex of C3H mouse cells by optical diffractometry and of changes in cell shape by Fourier analysis.
    Cytometry, 1986, Volume: 7, Issue:1

    Topics: Alkaloids; Animals; Benzimidazoles; Cells, Cultured; Computers; Cytoskeleton; Fourier Analysis; Histocytochemistry; Mathematics; Mice; Mice, Inbred C3H; Microscopy, Phase-Contrast; Microtubules; Nocodazole; Paclitaxel; Photomicrography

1986
Microtubule dynamics during the cell cycle: the effects of taxol and nocodazole on the microtubule system of Pt K2 cells at different stages of the mitotic cycle.
    International review of cytology, 1986, Volume: 101

    Topics: Alkaloids; Animals; Benzimidazoles; Cell Cycle; Cell Line; Interphase; Kidney; Marsupialia; Metaphase; Microscopy, Electron; Microtubules; Mitosis; Motion Pictures; Nocodazole; Paclitaxel; Prophase

1986
Microtubules and actin filaments are not critically involved in the biogenesis of epithelial cell surface polarity.
    The Journal of cell biology, 1986, Volume: 102, Issue:5

    Topics: Actin Cytoskeleton; Actins; Alkaloids; Animals; Benzimidazoles; Cell Compartmentation; Cell Line; Cell Membrane; Colchicine; Cytochalasin D; Cytochalasins; Cytoskeleton; Dogs; Epithelium; Exocytosis; Hemagglutinins, Viral; Kidney; Membrane Glycoproteins; Membrane Proteins; Microscopy, Electron; Microtubules; Nocodazole; Orthomyxoviridae; Paclitaxel; Tubulin; Vesicular stomatitis Indiana virus; Viral Envelope Proteins; Viral Proteins; Virus Replication

1986
A dissection of the mechanisms generating and stabilizing polarity in mouse 8- and 16-cell blastomeres: the role of cytoskeletal elements.
    Journal of embryology and experimental morphology, 1985, Volume: 90

    Topics: Alkaloids; Animals; Antineoplastic Agents; Benzimidazoles; Blastomeres; Cell Communication; Cell Division; Cells, Cultured; Cytochalasin D; Cytochalasins; Cytoskeleton; Mice; Microscopy, Electron, Scanning; Microtubules; Nocodazole; Paclitaxel

1985
Microtubules and the gonadotropic regulation of granulosa cell steroidogenesis.
    Endocrinology, 1987, Volume: 120, Issue:2

    Topics: 20-alpha-Dihydroprogesterone; Alkaloids; Animals; Benzimidazoles; Cells, Cultured; Colchicine; Female; Follicle Stimulating Hormone; Granulosa Cells; Kinetics; Microtubules; Nocodazole; Paclitaxel; Progesterone; Rats; Rats, Inbred Strains

1987
Microtubule-acting drugs lead to the nonpolarized delivery of the influenza hemagglutinin to the cell surface of polarized Madin-Darby canine kidney cells.
    The Journal of cell biology, 1987, Volume: 104, Issue:2

    Topics: Alkaloids; Animals; Benzimidazoles; Cell Line; Cell Membrane; Dogs; Golgi Apparatus; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Influenza A virus; Kidney; Microscopy, Electron; Microtubules; Mutation; Nocodazole; Paclitaxel; Temperature; Vesicular stomatitis Indiana virus; Viral Envelope Proteins

1987
Cytoplasmic reorganization during the resumption of meiosis in cultured preovulatory rat oocytes.
    Developmental biology, 1987, Volume: 120, Issue:1

    Topics: Alkaloids; Animals; Benzimidazoles; Bucladesine; Cells, Cultured; Chromatin; Cytoplasm; Female; Meiosis; Microscopy, Fluorescence; Microtubules; Nocodazole; Oocytes; Organoids; Ovulation; Paclitaxel; Rats; Rats, Inbred Strains

1987
Germinal vesicle migration and dissolution in Rana pipiens oocytes: effect of steroids and microtubule poisons.
    Cell differentiation, 1987, Volume: 20, Issue:4

    Topics: Alkaloids; Animals; Benzimidazoles; Cell Compartmentation; Cell Nucleus; Demecolcine; Estradiol; Meiosis; Microtubules; Movement; Nocodazole; Oocytes; Paclitaxel; Progesterone; Rana pipiens

1987
Postpolymerization detyrosination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules.
    The Journal of cell biology, 1987, Volume: 105, Issue:1

    Topics: Alkaloids; Animals; Azides; Benzimidazoles; Cell Line; Chlorocebus aethiops; Epithelial Cells; Fluorescent Antibody Technique; Kidney; Microtubules; Models, Biological; Nocodazole; Paclitaxel; Protein Processing, Post-Translational; Sodium Azide; Tubulin; Tyrosine; Vinblastine

1987
Sequential phosphorylation of chartin microtubule-associated proteins is regulated by the presence of microtubules.
    The Journal of cell biology, 1987, Volume: 105, Issue:1

    Topics: Alkaloids; Animals; Benzimidazoles; Cell Line; Microtubule-Associated Proteins; Microtubules; Nerve Growth Factors; Neurons; Nocodazole; Paclitaxel; Pheochromocytoma; Phosphorylation; Podophyllotoxin; Protein Kinases; Protein Processing, Post-Translational; Rats

1987
Control of microtubule nucleation and stability in Madin-Darby canine kidney cells: the occurrence of noncentrosomal, stable detyrosinated microtubules.
    The Journal of cell biology, 1987, Volume: 105, Issue:3

    Topics: Alkaloids; Animals; Benzimidazoles; Carboxypeptidases; Carboxypeptidases A; Cell Line; Cell Nucleus; Centrioles; Dogs; Kidney; Kinetics; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel; Tubulin; Tyrosine

1987
Microinjected carboxylated beads move predominantly poleward in sea urchin eggs.
    Cell motility and the cytoskeleton, 1987, Volume: 8, Issue:4

    Topics: Alkaloids; Animals; Benzimidazoles; Biological Transport; Cytoplasm; Microinjections; Microspheres; Microtubules; Mitosis; Nocodazole; Paclitaxel; Spindle Apparatus; Video Recording

1987
The cytoskeleton of the cultured human trabecular cell. Characterization and drug responses.
    Investigative ophthalmology & visual science, 1988, Volume: 29, Issue:2

    Topics: Alkaloids; Benzimidazoles; Cells, Cultured; Colchicine; Cytochalasin B; Cytoskeleton; Humans; Intermediate Filaments; Microtubules; Nocodazole; Paclitaxel; Trabecular Meshwork; Vimentin

1988
Dynamic behavior of the transferrin receptor followed in living epidermoid carcinoma (A431) cells with nanovid microscopy.
    Cell motility and the cytoskeleton, 1988, Volume: 9, Issue:1

    Topics: Alkaloids; Azides; Benzimidazoles; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Humans; Microscopy, Electron; Microscopy, Phase-Contrast; Microtubules; Nocodazole; Organoids; Paclitaxel; Receptors, Transferrin; Sodium Azide

1988
Dynamics of a fluorescent calmodulin analog in the mammalian mitotic spindle at metaphase.
    Cell motility and the cytoskeleton, 1988, Volume: 9, Issue:3

    Topics: Alkaloids; Animals; Benzimidazoles; Calmodulin; Cell Line; Fluoresceins; Fluorescence; In Vitro Techniques; Metaphase; Mitosis; Nocodazole; Paclitaxel; Spindle Apparatus; Tubulin

1988
Microtubule-granule relationships in motile human polymorphonuclear leukocytes.
    The Anatomical record, 1988, Volume: 221, Issue:3

    Topics: Alkaloids; Benzimidazoles; Cytochalasin B; Humans; Inclusion Bodies; Microscopy, Electron; Microscopy, Fluorescence; Microtubules; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nocodazole; Paclitaxel

1988
Presence and distribution of vimentin in cynomolgus monkey trabecular cells.
    The Anatomical record, 1988, Volume: 222, Issue:4

    Topics: Alkaloids; Animals; Benzimidazoles; Colchicine; Cytochalasin B; Fluorescent Antibody Technique; Macaca fascicularis; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Nocodazole; Paclitaxel; Tissue Distribution; Trabecular Meshwork; Vimentin

1988
Effect of microtubule reactive drugs on steroid- and centrifugation-induced germinal vesicle migration during goldfish oocyte meiosis.
    Biology of the cell, 1988, Volume: 64, Issue:3

    Topics: Alkaloids; Animals; Benzimidazoles; Cell Movement; Cell Nucleus; Centrifugation; Cytoskeleton; Demecolcine; Estradiol; Goldfish; Hydroxyprogesterones; Intermediate Filaments; Meiosis; Microtubules; Nocodazole; Oocytes; Oogenesis; Paclitaxel; Progesterone; Tubulin; Vinblastine

1988
Post-translational modifications of tubulin and the dynamics of microtubules in mouse oocytes and zygotes.
    Biology of the cell, 1988, Volume: 64, Issue:3

    Topics: Acetylation; Alkaloids; Animals; Benzimidazoles; Fluorescent Antibody Technique; Meiosis; Mice; Microtubules; Nocodazole; Oocytes; Paclitaxel; Protein Processing, Post-Translational; Tubulin; Tyrosine; Zygote

1988
Visualization of assembled and disassembled microtubule protein by double label fluorescence microscopy.
    Cell biology international reports, 1981, Volume: 5, Issue:4

    Topics: Animals; Antibodies; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzimidazoles; Carbamates; Colchicine; Female; Granulosa Cells; Microtubules; Nocodazole; Paclitaxel; Rats; Terpenes; Tubulin

1981
Unpolymerized tubulin modulates the level of tubulin mRNAs.
    Cell, 1981, Volume: 25, Issue:2

    Topics: Alkaloids; Animals; Benzimidazoles; Carbamates; Cell Line; Colchicine; Cricetinae; Drosophila; Kinetics; Mice; Nocodazole; Paclitaxel; Polymers; RNA, Messenger; Tubulin; Vinblastine

1981
Microtubule assembly in living cells after release from nocodazole block: the effects of metabolic inhibitors, taxol and PH.
    Cell biology international reports, 1981, Volume: 5, Issue:9

    Topics: Alkaloids; Animals; Azides; Benzimidazoles; Carbamates; Cell Line; Hydrogen-Ion Concentration; Kidney; Marsupialia; Microtubules; Nocodazole; Paclitaxel

1981
Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:9

    Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Benzimidazoles; Carbamates; Cells, Cultured; Centrioles; Centromere; Chromosomes; Humans; Mice; Microtubules; Mitosis; Nocodazole; Organoids; Paclitaxel; Protein Binding; Tubulin

1981
Immunoelectron microscopic localization of the 210,000-mol wt microtubule-associated protein in cultured cells of primates.
    The Journal of cell biology, 1981, Volume: 91, Issue:2 Pt 1

    Topics: Alkaloids; Animals; Azides; Benzimidazoles; Carbamates; Cell Line; Centrioles; Chlorocebus aethiops; Cytoskeleton; Humans; Immunoenzyme Techniques; Interphase; Macropodidae; Mice; Microscopy, Electron; Microtubule-Associated Proteins; Microtubules; Mitosis; Nocodazole; Paclitaxel; Proteins; Sodium Azide; Vinblastine

1981
Interactions of a new antimitotic agent, NSC-181928, with purified tubulin.
    Biochemical and biophysical research communications, 1982, Feb-11, Volume: 104, Issue:3

    Topics: Alkaloids; Animals; Benzimidazoles; Carbamates; Cattle; Colchicine; Guanosine Triphosphate; Hydrolysis; Nocodazole; Paclitaxel; Polymers; Pyrazines; Temperature; Tubulin

1982
Effects of taxol and nocodazole on insulin secretion from isolated rat islets of Langerhans.
    Bioscience reports, 1982, Volume: 2, Issue:10

    Topics: Alkaloids; Animals; Benzimidazoles; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Microscopy, Electron; Nocodazole; Paclitaxel; Rats; Rats, Inbred Strains

1982
The interaction between microtubules and intermediate filaments in cultured cells treated with taxol and nocodazole.
    Cell biology international reports, 1983, Volume: 7, Issue:1

    Topics: Alkaloids; Animals; Benzimidazoles; Cells, Cultured; Cytoskeleton; Fluorescent Antibody Technique; Mice; Microtubules; Nocodazole; Paclitaxel; Swine

1983
The intracellular movement of endocytic vesicles in cultured granulosa cells.
    Cell motility, 1982, Volume: 2, Issue:6

    Topics: Alkaloids; Animals; Benzimidazoles; Cells, Cultured; Concanavalin A; Cytoskeleton; Endocytosis; Female; Granulosa Cells; Microtubules; Nocodazole; Paclitaxel; Rats; Receptors, Concanavalin A

1982
Vinblastine inhibits the maturation of the precursor of mitochondrial aspartate aminotransferase. Vincristine and six other cytoskeleton inhibitors do not show this effect.
    Biochemical and biophysical research communications, 1983, Aug-30, Volume: 115, Issue:1

    Topics: Alkaloids; Animals; Aspartate Aminotransferases; Benzimidazoles; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Chick Embryo; Colchicine; Cytochalasin D; Cytochalasins; Enzyme Precursors; Fibroblasts; Kinetics; Mitochondria; Nocodazole; Oxygen Consumption; Paclitaxel; Phalloidine; Podophyllotoxin; Vinblastine

1983
The effects of taxol on the organization of the cytoskeleton in cultured ovarian granulosa cells.
    European journal of cell biology, 1983, Volume: 31, Issue:1

    Topics: Alkaloids; Animals; Benzimidazoles; Cells, Cultured; Colchicine; Cytoskeleton; Female; Granulosa Cells; Intermediate Filament Proteins; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel; Rats; Tubulin

1983
Vimentin filaments and centrosomes. Are they associated?
    Experimental cell research, 1984, Volume: 150, Issue:2

    Topics: Alkaloids; Benzimidazoles; Centrioles; Cytoskeleton; Fluorescent Antibody Technique; HeLa Cells; Humans; Intermediate Filament Proteins; Microscopy, Electron; Microtubules; Nocodazole; Organoids; Paclitaxel; Vimentin

1984
The cytoskeletal system of nucleated erythrocytes. III. Marginal band function in mature cells.
    The Journal of cell biology, 1984, Volume: 98, Issue:6

    Topics: Alkaloids; Animals; Benzimidazoles; Colchicine; Dogfish; Erythrocytes; Microscopy, Electron, Scanning; Microtubules; Nocodazole; Osmolar Concentration; Paclitaxel; Stress, Mechanical; Sucrose

1984
Analysis of the role of microfilaments and microtubules in acquisition of bipolarity and elongation of fibroblasts in hydrated collagen gels.
    The Journal of cell biology, 1984, Volume: 99, Issue:2

    Topics: Alkaloids; Animals; Benzimidazoles; Cells, Cultured; Chick Embryo; Collagen; Cornea; Cytochalasin D; Cytochalasins; Cytoskeleton; Fibroblasts; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel

1984
Effect of microtubule inhibitors on the expansion of hypoblast and margin of overgrowth of chick blastoderms.
    Journal of embryology and experimental morphology, 1984, Volume: 81

    Topics: Alkaloids; Animals; Benzimidazoles; Blastoderm; Cell Movement; Chick Embryo; Culture Techniques; Dose-Response Relationship, Drug; Immunoenzyme Techniques; Microscopy, Phase-Contrast; Microtubules; Nocodazole; Paclitaxel

1984
Microtubules influence compaction in preimplantation mouse embryos.
    Journal of embryology and experimental morphology, 1984, Volume: 84

    Topics: Alkaloids; Animals; Benzimidazoles; Blastocyst; Cells, Cultured; Mice; Microscopy, Electron, Scanning; Microtubules; Nocodazole; Paclitaxel; Tubulin

1984
Elevation of cyclic AMP activates an actin-dependent contraction in teleost retinal rods.
    The Journal of cell biology, 1982, Volume: 95, Issue:2 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Actins; Alkaloids; Animals; Benzimidazoles; Bucladesine; Cold Temperature; Culture Techniques; Cyclic AMP; Cytochalasin D; Cytochalasins; Cytoskeleton; Darkness; Fishes; Light; Microtubules; Nocodazole; Paclitaxel; Photoreceptor Cells

1982
Autoregulatory control of expression of alpha and beta tubulin.
    Journal of submicroscopic cytology, 1983, Volume: 15, Issue:1

    Topics: Alkaloids; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzimidazoles; Cell Line; Colchicine; Cricetinae; Cricetulus; Female; Gene Expression Regulation; Homeostasis; Nocodazole; Ovary; Paclitaxel; RNA; Tubulin; Vinblastine

1983
Contraction due to microtubule disruption is associated with increased phosphorylation of myosin regulatory light chain.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Oct-24, Volume: 92, Issue:22

    Topics: Animals; Cattle; Cells, Cultured; Chick Embryo; Culture Media; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Isometric Contraction; Kinetics; Microtubules; Models, Biological; Muscles; Myosin Light Chains; Nocodazole; Paclitaxel; Phosphorylation; Time Factors

1995
Redistribution of microtubules and Golgi apparatus in herpes simplex virus-infected cells and their role in viral exocytosis.
    Journal of virology, 1995, Volume: 69, Issue:12

    Topics: Animals; Antibodies, Monoclonal; Cell Line; Chlorocebus aethiops; Coatomer Protein; Cricetinae; Exocytosis; Fluorescent Antibody Technique; Golgi Apparatus; Herpesvirus 1, Human; Humans; Kidney; Kinetics; Membrane Proteins; Mice; Microscopy, Electron; Microtubule-Associated Proteins; Microtubules; Nocodazole; Paclitaxel; Time Factors; Tubulin; Tumor Cells, Cultured; Vero Cells; Virus Replication

1995
Induction of apoptosis in cultured retinoblastoma cells by the protein phosphatase inhibitor, okadaic acid.
    Journal of cancer research and clinical oncology, 1995, Volume: 121, Issue:12

    Topics: Apoptosis; Calcimycin; Cell Cycle; Cell Survival; Child, Preschool; Cholera Toxin; Colforsin; DNA, Neoplasm; Enzyme Inhibitors; Ethers, Cyclic; Etoposide; Flow Cytometry; HL-60 Cells; Humans; Male; Mitosis; Nocodazole; Okadaic Acid; Paclitaxel; Phosphoprotein Phosphatases; Retinoblastoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1995
Identification of a 102 kDa protein (cytocentrin) immunologically related to keratin 19, which is a cytoplasmically derived component of the mitotic spindle pole.
    Journal of cell science, 1993, Volume: 106 ( Pt 3)

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Base Sequence; Cell Cycle; Cell Line; Cross Reactions; Cytoplasm; Epitopes; Keratins; Lamins; Molecular Sequence Data; Nocodazole; Nuclear Proteins; Paclitaxel; Proteins; Rats; Spindle Apparatus; Tubulin

1993
Nuclear migration of NF-kappa B correlates with TNF-alpha mRNA accumulation.
    Journal of inflammation, 1995, Volume: 45, Issue:1

    Topics: Animals; Base Sequence; Biological Transport; Bone Marrow Cells; Cell Nucleus; Cells, Cultured; Cyclic AMP; Free Radical Scavengers; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Sequence Data; NF-kappa B; Nocodazole; Paclitaxel; RNA, Messenger; Serine Proteinase Inhibitors; T-Lymphocytes; Tosylphenylalanyl Chloromethyl Ketone; Tumor Necrosis Factor-alpha

1995
Effect of microtubule network disturbance by nocodazole and docetaxel (Taxotere) on protein secretion in rat extraorbital lacrimal and parotid glands.
    European journal of cell biology, 1995, Volume: 67, Issue:3

    Topics: Animals; Bucladesine; Calcimycin; Carbachol; Docetaxel; Dose-Response Relationship, Drug; Epinephrine; Fluorescent Antibody Technique; Galactose; Glycoproteins; Isoproterenol; Lacrimal Apparatus; Male; Microtubules; Nocodazole; Paclitaxel; Parotid Gland; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Taxoids

1995
Identification of a new microtubule-interacting protein Mip-90.
    European journal of cell biology, 1995, Volume: 67, Issue:2

    Topics: Amino Acid Sequence; Calmodulin; Chromatography, Affinity; Cross Reactions; Cytoplasm; HeLa Cells; Hot Temperature; Humans; Microtubule-Associated Proteins; Microtubules; Molecular Sequence Data; Molecular Weight; Neuroblastoma; Nocodazole; Paclitaxel; Peptide Fragments; tau Proteins; Tubulin; Tumor Cells, Cultured

1995
Microtubule stabilization and potentiation of taxol activity by the creatine analog cyclocreatine.
    Anti-cancer drugs, 1995, Volume: 6, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Colony-Forming Units Assay; Creatinine; Drug Synergism; Female; Fluorescent Antibody Technique; Humans; Microtubules; Nocodazole; Paclitaxel; Tumor Cells, Cultured; Uterine Cervical Neoplasms

1995
Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix.
    Journal of cell science, 1995, Volume: 108 ( Pt 6)

    Topics: Animals; Cell Adhesion; Cell Size; Cells, Cultured; Cytoskeleton; Extracellular Matrix Proteins; Liver; Male; Nocodazole; Paclitaxel; Rats; Rats, Wistar

1995
Nocodazole and taxol affect subcellular compartments but not secretory activity of GH3B6 prolactin cells.
    European journal of cell biology, 1993, Volume: 60, Issue:2

    Topics: Animals; Biological Transport; Cell Compartmentation; Cell Line; Cell Size; Golgi Apparatus; Keratins; Mannosidases; Microtubules; Nocodazole; Paclitaxel; Prolactin; Rats

1993
The microtubule cytoskeleton in human phagocytic leukocytes is a highly dynamic structure.
    European journal of cell biology, 1995, Volume: 66, Issue:3

    Topics: Drug-Related Side Effects and Adverse Reactions; Eosinophils; Female; Fluorescent Antibody Technique; Humans; Leukocytes; Microtubules; Monocytes; Neutrophils; Nocodazole; Ovarian Neoplasms; Paclitaxel; Phagocytes; Tubulin

1995
The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeleton.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:6

    Topics: Alkaloids; Animals; Antibodies, Monoclonal; Carrier Proteins; Cells, Cultured; Cytochalasin B; Cytoskeleton; Demecolcine; Embryo, Mammalian; Immunohistochemistry; Kinetics; Lumicolchicines; Membrane Proteins; Neurons; Nocodazole; Paclitaxel; Rats; Rats, Wistar; Receptors, Glycine; Spinal Cord; Synapses; Time Factors

1995
Interactions among endoplasmic reticulum, microtubules, and retrograde movements of the cell surface.
    Cell motility and the cytoskeleton, 1994, Volume: 29, Issue:4

    Topics: Actins; Animals; Carbocyanines; Cell Line; Cell Membrane; Cytochalasins; Endoplasmic Reticulum; Kidney; Microscopy, Fluorescence; Microspheres; Microtubules; Movement; Nocodazole; Organotin Compounds; Paclitaxel; Xenopus laevis

1994
Characteristics of pronuclear migration in Beroe ovata.
    Cell motility and the cytoskeleton, 1994, Volume: 29, Issue:4

    Topics: Animals; Benzimidazoles; Cell Nucleus; Cnidaria; Cytochalasin B; Endoplasmic Reticulum; Female; Fertilization; Griseofulvin; Microscopy, Electron; Microscopy, Fluorescence; Microscopy, Video; Microtubules; Movement; Nocodazole; Nuclear Envelope; Ovum; Paclitaxel; Zygote

1994
Antimicrotubule agents induce polyploidization of human leukaemic cell lines with megakaryocytic features.
    European journal of clinical investigation, 1993, Volume: 23, Issue:10

    Topics: Cell Division; Colchicine; Demecolcine; DNA; Flow Cytometry; Humans; Leukemia; Lumicolchicines; Megakaryocytes; Microtubules; Nocodazole; Paclitaxel; Polyploidy; Tumor Cells, Cultured

1993
Regulation of vesicle transport in CV-1 cells and extracts.
    Journal of cell science, 1993, Volume: 106 ( Pt 3)

    Topics: Adenylyl Cyclases; Animals; Biological Transport, Active; Cell Line; Cell Membrane; Chlorocebus aethiops; Enzyme Activation; Fluorescent Antibody Technique; Microtubules; Nocodazole; Organelles; Paclitaxel

1993
Motility and invasive potency of murine T-lymphoma cells: effect of microtubule inhibitors.
    Cell biology international, 1994, Volume: 18, Issue:1

    Topics: Animals; Cell Movement; Fibroblasts; Fourier Analysis; Leukemia L5178; Lymphoma, T-Cell; Mice; Mice, Inbred DBA; Microtubules; Neoplasm Invasiveness; Nocodazole; Paclitaxel; Tumor Cells, Cultured

1994
Effects of the microtubule depolymerizing and stabilizing agents Nocodazole and taxol on glucose-induced insulin secretion from hamster islet tumor (HIT) cells.
    Journal of submicroscopic cytology and pathology, 1994, Volume: 26, Issue:2

    Topics: Adenoma, Islet Cell; Animals; Colforsin; Cricetinae; Fluorescent Antibody Technique; Glucose; Insulin; Insulin Secretion; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel; Pancreatic Neoplasms; Tumor Cells, Cultured

1994
Gamma-aminobutyric acidA receptor function is inhibited by microtubule depolymerization.
    The Journal of biological chemistry, 1994, Jul-29, Volume: 269, Issue:30

    Topics: Animals; Biological Transport; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Chlorides; Colchicine; Convulsants; Dose-Response Relationship, Drug; Flunitrazepam; Histones; Humans; Lumicolchicines; Membranes; Mice; Microtubules; Muscimol; Nocodazole; Paclitaxel; Phosphorylation; Receptors, GABA-A; Vinblastine; Xenopus

1994
Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase.
    Cancer research, 1994, Aug-15, Volume: 54, Issue:16

    Topics: Anaphase; Cell Cycle; Colonic Neoplasms; Drug Screening Assays, Antitumor; G1 Phase; Humans; Nocodazole; Paclitaxel; Spindle Apparatus; Telophase; Tumor Cells, Cultured

1994
Cell cycle arrest by Colcemid differs in human normal and tumor cells.
    Cancer research, 1994, Sep-15, Volume: 54, Issue:18

    Topics: Ataxia Telangiectasia; Cell Cycle; Cell Line; Demecolcine; Fibroblasts; Humans; Lymphocytes; Mitosis; Nocodazole; Paclitaxel; Time Factors; Tumor Cells, Cultured; Vinblastine

1994
A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts.
    Cell, 1994, Nov-04, Volume: 79, Issue:3

    Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cell-Free System; Cyclins; Dual Specificity Phosphatase 1; Enzyme Activation; Glycogen Synthase Kinase 3; Histones; Immediate-Early Proteins; Male; Microtubules; Mitosis; Models, Biological; Nocodazole; Ovum; Paclitaxel; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-mos; Spermatozoa; Spindle Apparatus; Xenopus

1994
Microtubule arrays of the zebrafish yolk cell: organization and function during epiboly.
    Development (Cambridge, England), 1994, Volume: 120, Issue:9

    Topics: Animals; Blastoderm; Blotting, Western; Cleavage Stage, Ovum; Female; Immunohistochemistry; Microscopy, Fluorescence; Microtubules; Models, Biological; Nocodazole; Paclitaxel; Tubulin; Zebrafish

1994
Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells.
    The Journal of cell biology, 1994, Volume: 127, Issue:3

    Topics: 2-Aminopurine; Animals; CDC2 Protein Kinase; Cell Line; Cricetinae; Flow Cytometry; Kidney; Kinetics; Microtubules; Mitosis; Nocodazole; Paclitaxel; Protamine Kinase; Signal Transduction

1994
The initiation of neurite outgrowth by sympathetic neurons grown in vitro does not depend on assembly of microtubules.
    The Journal of cell biology, 1994, Volume: 127, Issue:5

    Topics: Animals; Cells, Cultured; Chick Embryo; Colchicine; Ganglia, Sympathetic; Microscopy, Confocal; Microscopy, Video; Microtubules; Neurites; Neurons; Nocodazole; Paclitaxel; Tubulin

1994
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells.
    Cancer research, 1994, Dec-15, Volume: 54, Issue:24

    Topics: Animals; Cathepsin B; Cell Membrane; Colorectal Neoplasms; Fibrocystic Breast Disease; Humans; Hydrogen-Ion Concentration; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Microtubules; Nocodazole; Paclitaxel; Tumor Cells, Cultured

1994
Production of a unique antibody specific for membrane ruffles and its use to characterize the behavior of two distinct types of ruffles.
    The Journal of cell biology, 1993, Volume: 120, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antibodies, Monoclonal; Antigens, Surface; Calmodulin; Cell Membrane; Chick Embryo; Culture Media, Serum-Free; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Isoquinolines; Kinetics; Membrane Proteins; Molecular Weight; Nocodazole; Paclitaxel; Piperazines; Protein Kinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors

1993
Sperm chromatin acquires an activity that induces microtubule assembly during residence in the cytoplasm of metaphase oocytes of the mouse.
    Chromosoma, 1993, Volume: 102, Issue:4

    Topics: Animals; Chromatin; Cytoplasm; Female; In Vitro Techniques; Male; Metaphase; Mice; Microtubules; Nocodazole; Oocytes; Paclitaxel; Sperm-Ovum Interactions; Spermatozoa

1993
Cytoskeletal organization of rat oocytes during metaphase II arrest and following abortive activation: a study by confocal laser scanning microscopy.
    Molecular reproduction and development, 1993, Volume: 35, Issue:2

    Topics: Animals; Cytoskeleton; Female; Lasers; Meiosis; Metaphase; Mice; Microscopy; Microscopy, Electron; Microscopy, Fluorescence; Microtubules; Nocodazole; Oocytes; Paclitaxel; Parthenogenesis; Rats; Rats, Wistar; Spindle Apparatus

1993
Reversible polyglutamylation of alpha- and beta-tubulin and microtubule dynamics in mouse brain neurons.
    Molecular biology of the cell, 1993, Volume: 4, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Brain; Cells, Cultured; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Immunoblotting; Mice; Microtubules; Neurons; Nocodazole; Paclitaxel; Polymers; Stereoisomerism; Tubulin

1993
Protection from adriamycin cytotoxicity in L1210 cells by brefeldin A.
    Cancer research, 1993, Nov-01, Volume: 53, Issue:21

    Topics: Amsacrine; Animals; Biological Transport; Brefeldin A; Cell Survival; Cyclopentanes; DNA Damage; DNA Repair; Doxorubicin; Drug Synergism; Endoplasmic Reticulum; Etoposide; Golgi Apparatus; Kinetics; Leukemia L1210; Mice; Microtubules; Nocodazole; Paclitaxel; Temperature; Tumor Cells, Cultured; Tumor Stem Cell Assay

1993
Dynamics of organelles in the mitotic spindles of living cells: membrane and microtubule interactions.
    Cell motility and the cytoskeleton, 1993, Volume: 26, Issue:1

    Topics: Anaphase; Animals; Carbocyanines; Cell Cycle; Cell Line; Cell Membrane; Epithelial Cells; Epithelium; Fluorescent Antibody Technique; Image Processing, Computer-Assisted; Kidney; Macropodidae; Metaphase; Microscopy; Microtubules; Mitosis; Nocodazole; Organelles; Paclitaxel; Prophase; Spindle Apparatus; Swine; Tubulin

1993
Microtubule-active drugs taxol, vinblastine, and nocodazole increase the levels of transcriptionally active p53.
    Cancer research, 1995, Dec-15, Volume: 55, Issue:24

    Topics: 3T3 Cells; Animals; Base Sequence; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; Gene Expression Regulation; Mice; Microtubules; Molecular Sequence Data; Nocodazole; Oligodeoxyribonucleotides; Paclitaxel; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Tumor Suppressor Protein p53; Vinblastine

1995
Stable, detyrosinated microtubules function to localize vimentin intermediate filaments in fibroblasts.
    The Journal of cell biology, 1995, Volume: 131, Issue:5

    Topics: 3T3 Cells; Animals; Antibodies, Monoclonal; Fibroblasts; Intermediate Filaments; Mice; Microtubules; Nocodazole; Paclitaxel; Serum Albumin, Bovine; Tubulin; Tyrosine; Vimentin

1995
Effects of nocodazole and taxol on glycine evoked currents on rat spinal cord neurones in culture.
    Neuroreport, 1995, Oct-02, Volume: 6, Issue:14

    Topics: Adenosine Triphosphate; Animals; Biopolymers; Cells, Cultured; Chloride Channels; Evoked Potentials; Guanosine Triphosphate; Microtubules; Neurons; Nocodazole; Paclitaxel; Patch-Clamp Techniques; Rats; Receptors, Glycine; Spinal Cord

1995
Low concentrations of nocodazole interfere with fibroblast locomotion without significantly affecting microtubule level: implications for the role of dynamic microtubules in cell locomotion.
    Journal of cell science, 1995, Volume: 108 ( Pt 11)

    Topics: Animals; Cell Movement; Dose-Response Relationship, Drug; Fibroblasts; Kidney; Microscopy, Video; Microtubules; Nocodazole; Paclitaxel; Rats

1995
Gonococcal opacity protein promotes bacterial entry-associated rearrangements of the epithelial cell actin cytoskeleton.
    Infection and immunity, 1996, Volume: 64, Issue:5

    Topics: Actins; Antigens, Bacterial; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Cell Line; Clathrin; Colchicine; Cytochalasin D; Cytoskeleton; Endocytosis; Epithelium; Escherichia coli; Fluorescent Antibody Technique, Indirect; Humans; Microtubules; Neisseria gonorrhoeae; Nocodazole; Paclitaxel

1996
Activation of smooth muscle alpha-actin promoter in ras-transformed cells by treatments with antimitotic agents: correlation with stimulation of SRF:SRE mediated gene transcription.
    Journal of biochemistry, 1995, Volume: 118, Issue:6

    Topics: Actin Cytoskeleton; Actins; Animals; Antineoplastic Agents; Base Sequence; Cell Line; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Colchicine; Consensus Sequence; DNA Primers; DNA-Binding Proteins; Gene Expression Regulation; Genes, ras; Humans; Molecular Sequence Data; Muscle, Smooth; Nocodazole; Oligodeoxyribonucleotides; Paclitaxel; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Thymidine Kinase; Transcription, Genetic; Transfection; Vinblastine; Vincristine; Xenopus laevis

1995
Microtubule-active agents mimic lipopolysaccharides in priming macrophages for enhanced arachidonic acid metabolism.
    Journal of inflammation, 1996, Volume: 46, Issue:2

    Topics: Animals; Arachidonic Acid; Cells, Cultured; Colchicine; Female; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Microtubules; Nocodazole; Paclitaxel; Tetradecanoylphorbol Acetate; Zymosan

1996
The role of microtubules and inositol triphosphate induced Ca2+ release in the tyrosine phosphorylation of mitogen-activated protein kinase in extracts of Xenopus laevis oocytes.
    Zygote (Cambridge, England), 1996, Volume: 4, Issue:1

    Topics: Animals; Biopolymers; Calcium; Enzyme Activation; Female; Inositol Phosphates; Microsomes; Microtubules; Nocodazole; Oocytes; Paclitaxel; Phosphorylation; Protein Kinases; Tyrosine; Xenopus laevis

1996
Involvement of gamma and beta actin isoforms in mouse neuroblastoma differentiation.
    The European journal of neuroscience, 1996, Volume: 8, Issue:7

    Topics: Actins; Animals; Cell Differentiation; Cytochalasin D; Cytoskeleton; Mice; Nerve Tissue Proteins; Neurites; Neuroblastoma; Neurons; Nocodazole; Paclitaxel; Phalloidine; Tumor Cells, Cultured

1996
Intestinal epithelial cytoskeleton selectively constrains lumen-to-tissue migration of neutrophils.
    The American journal of physiology, 1996, Volume: 271, Issue:1 Pt 1

    Topics: Actins; Cell Movement; Cytoskeleton; Egtazic Acid; Humans; Intestinal Mucosa; Microtubules; Neutrophils; Nocodazole; Paclitaxel; Peptides, Cyclic

1996
Cytoskeleton-dependent activation of the inducible nitric oxide synthase in cultured aortic smooth muscle cells.
    British journal of pharmacology, 1996, Volume: 118, Issue:5

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Aorta, Thoracic; Blotting, Western; Cells, Cultured; Colchicine; Cyclic GMP; Cytochalasins; Cytoskeleton; Enzyme Induction; Gout Suppressants; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nocodazole; Paclitaxel; Rats; Rats, Wistar; RNA

1996
Identification of a human mitotic checkpoint gene: hsMAD2.
    Science (New York, N.Y.), 1996, Oct-11, Volume: 274, Issue:5285

    Topics: Amino Acid Sequence; Anaphase; Calcium-Binding Proteins; Carrier Proteins; Cell Cycle Proteins; Electroporation; HeLa Cells; Humans; Interphase; Kinetochores; Mad2 Proteins; Metaphase; Mitosis; Molecular Sequence Data; Nocodazole; Paclitaxel; Repressor Proteins; Spindle Apparatus; Tumor Cells, Cultured

1996
gamma-Tubulin redistribution in taxol-treated mitotic cells probed by monoclonal antibodies.
    Cell motility and the cytoskeleton, 1996, Volume: 33, Issue:1

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; HeLa Cells; Humans; Macropodidae; Mice; Mice, Inbred BALB C; Microtubules; Mitosis; Molecular Sequence Data; Nocodazole; Paclitaxel; Tubulin; Tumor Cells, Cultured; Turkey

1996
Interaction of microtubules with peroxisomes. Tubular and spherical peroxisomes in HepG2 cells and their alterations induced by microtubule-active drugs.
    European journal of cell biology, 1996, Volume: 69, Issue:1

    Topics: Actin Cytoskeleton; Animals; CHO Cells; Cricetinae; Cytochalasin B; Cytochalasin D; Demecolcine; Heterocyclic Compounds; Humans; Microbodies; Microscopy, Confocal; Microtubules; Nocodazole; Paclitaxel; Rats; Tumor Cells, Cultured; Vinblastine

1996
Function of spindle microtubules in directing cortical movement and actin filament organization in dividing cultured cells.
    Journal of cell science, 1996, Volume: 109 ( Pt 8)

    Topics: Actins; Anaphase; Animals; Cell Division; Cells, Cultured; Kidney; Microtubules; Mitosis; Nocodazole; Paclitaxel; Rats; Spindle Apparatus

1996
Oncoprotein 18 is a phosphorylation-responsive regulator of microtubule dynamics.
    The EMBO journal, 1996, Oct-01, Volume: 15, Issue:19

    Topics: Amino Acid Sequence; Cadmium; Cell Cycle; Cyclin-Dependent Kinases; DNA, Neoplasm; Edetic Acid; Gene Expression Regulation; Humans; Leukemia, Erythroblastic, Acute; Metaphase; Microtubule Proteins; Microtubules; Mutation; Nocodazole; Paclitaxel; Phenotype; Phosphoproteins; Phosphorylation; Polymers; Stathmin; Tubulin; Tumor Cells, Cultured

1996
Differential Taxol-dependent arrest of transformed and nontransformed cells in the G1 phase of the cell cycle, and specific-related mortality of transformed cells.
    The Journal of cell biology, 1996, Volume: 135, Issue:3

    Topics: Animals; Antigens, Polyomavirus Transforming; Antineoplastic Agents, Phytogenic; Apoptosis; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Line; Cell Line, Transformed; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; Fibroblasts; G1 Phase; Humans; Hydroxyurea; Microtubule-Associated Proteins; Microtubules; Nocodazole; Paclitaxel; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Rats; Retinoblastoma Protein; Simian virus 40; Tumor Suppressor Proteins

1996
Involvement of microtubules in the control of adhesion-dependent signal transduction.
    Current biology : CB, 1996, Oct-01, Volume: 6, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Actin Cytoskeleton; Alkaloids; Animals; Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; DNA; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Indoles; Integrins; Isoflavones; Mice; Microtubules; Myosin-Light-Chain Kinase; Nocodazole; Paclitaxel; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine; Vinblastine

1996
Paclitaxel and nocodazole differentially alter endocytosis in cultured cells.
    Pharmaceutical research, 1996, Volume: 13, Issue:11

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; Endocytosis; Fluorescein-5-isothiocyanate; Horseradish Peroxidase; Iodine Radioisotopes; Kidney; Lysosomes; Microtubules; Nocodazole; Paclitaxel; Receptors, Transferrin; Serum Albumin, Bovine; Transferrin

1996
Microtubules and microfilaments participate in the inhibition of synaptosomal noradrenaline release by tetanus toxin.
    Journal of neurochemistry, 1997, Volume: 68, Issue:2

    Topics: Actin Cytoskeleton; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Barium; Cadaverine; Calcium; Cerebral Cortex; Colchicine; Cytochalasin D; Cytoskeleton; Endopeptidases; Energy Metabolism; Enzyme Inhibitors; Gout Suppressants; Membrane Proteins; Microtubules; Nerve Tissue Proteins; Nocodazole; Norepinephrine; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Potassium; R-SNARE Proteins; Rats; Synaptic Vesicles; Synaptosomes; Tetanus Toxin; Transglutaminases

1997
Visualization of the peroxisomal compartment in living mammalian cells: dynamic behavior and association with microtubules.
    The Journal of cell biology, 1997, Jan-13, Volume: 136, Issue:1

    Topics: Animals; Cell Compartmentation; Cell Cycle; Cell Line; Demecolcine; Fibroblasts; Green Fluorescent Proteins; Haplorhini; Image Processing, Computer-Assisted; Kidney; Luminescent Proteins; Microbodies; Microscopy, Confocal; Microtubules; Mitosis; Nocodazole; Paclitaxel; Protein Sorting Signals; Recombinant Fusion Proteins; Vinblastine

1997
Chemical induction of mitotic checkpoint override in mammalian cells results in aneuploidy following a transient tetraploid state.
    Mutation research, 1996, Volume: 372, Issue:2

    Topics: 2-Aminopurine; Aneuploidy; Animals; Cell Cycle; CHO Cells; Cricetinae; Cytochalasin B; Diketopiperazines; Enzyme Inhibitors; Microtubules; Mitosis; Nocodazole; Paclitaxel; Piperazines; Polyploidy; Protein Kinase Inhibitors; Topoisomerase II Inhibitors

1996
Microtubule depolymerization selectively down-regulates the synthesis of proinflammatory secretory nonpancreatic phospholipase A2.
    Laboratory investigation; a journal of technical methods and pathology, 1997, Volume: 76, Issue:2

    Topics: Animals; Cells, Cultured; Colchicine; Down-Regulation; Interleukin-1; Microtubules; Nocodazole; Osteoblasts; Paclitaxel; Phospholipases A; Phospholipases A2; Rats; Tumor Necrosis Factor-alpha; Vinblastine

1997
Microtubule disruption reveals that Spemann's organizer is subdivided into two domains by the vegetal alignment zone.
    Development (Cambridge, England), 1997, Volume: 124, Issue:4

    Topics: Animals; Cell Differentiation; Cell Movement; Culture Techniques; Embryonic Development; Embryonic Induction; Gastrula; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Mesoderm; Microscopy, Video; Microtubules; Morphogenesis; Nocodazole; Paclitaxel; Proteins; Xenopus; Xenopus Proteins

1997
Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus.
    The Journal of cell biology, 1997, Mar-10, Volume: 136, Issue:5

    Topics: Actin Cytoskeleton; Animals; Biological Transport; Capsid; Capsid Proteins; Cell Nucleus; Chlorocebus aethiops; Cytochalasin D; Cytoplasm; Dyneins; Herpesvirus 1, Human; Immediate-Early Proteins; Microtubules; Nocodazole; Paclitaxel; Vero Cells

1997
Pretreatment by tubulin agents decreases C-MYC induction in human colon carcinoma cell line HT29-D4.
    Biochemical and biophysical research communications, 1997, Feb-24, Volume: 231, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Cell Line; Docetaxel; Gene Expression Regulation, Neoplastic; Genes, myc; HT29 Cells; Humans; Microtubules; Nocodazole; Paclitaxel; Precipitin Tests; Protein Binding; Proto-Oncogene Proteins c-myc; RNA, Messenger; RNA, Neoplasm; Taxoids; Tubulin

1997
Invasion of cultured human epithelial cells by Klebsiella pneumoniae isolated from the urinary tract.
    Infection and immunity, 1997, Volume: 65, Issue:7

    Topics: Bacterial Proteins; Cadaverine; Cells, Cultured; Chloramphenicol; Colchicine; Cytochalasin D; Demecolcine; Endocytosis; Epithelial Cells; Epithelium; Humans; Ionophores; Klebsiella pneumoniae; Microtubules; Monensin; Nocodazole; Nucleic Acid Synthesis Inhibitors; Ouabain; Paclitaxel; Protein Synthesis Inhibitors; Salmonella typhi; Urinary Tract; Urinary Tract Infections

1997
Microtubule dynamics regulates the level of endothelin-B receptor in rat cultured astrocytes.
    Journal of neurochemistry, 1997, Volume: 69, Issue:2

    Topics: Animals; Astrocytes; Blotting, Northern; Cell Differentiation; Cell Division; Cells, Cultured; Colchicine; DNA; Endothelin-1; Gene Expression; Inositol Phosphates; Microtubules; Nocodazole; Paclitaxel; Rats; Receptor, Endothelin B; Receptors, Endothelin; RNA, Messenger

1997
Posttranslational modification of tubulin by palmitoylation: I. In vivo and cell-free studies.
    Molecular biology of the cell, 1997, Volume: 8, Issue:4

    Topics: Animals; Blood Platelets; Brain Chemistry; Cell Membrane; Cell-Free System; Demecolcine; Guanosine Triphosphate; Humans; Male; Microtubules; Nocodazole; Paclitaxel; Palmitoyl Coenzyme A; Podophyllotoxin; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Substrate Specificity; Swine; Thrombin; Tubulin; Vinblastine

1997
Stereoscopic analysis of microtubule pattern around the centrosome in interphase PK cells after treatment with taxol and nocodazole.
    Membrane & cell biology, 1997, Volume: 11, Issue:1

    Topics: Animals; Cells, Cultured; Centrosome; Epithelial Cells; Interphase; Kidney; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel; Swine; Tubulin

1997
Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction.
    Molecular biology of the cell, 1997, Volume: 8, Issue:8

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cattle; Cytoskeleton; Endothelium; Fibronectins; Humans; Lysophospholipids; Microfilament Proteins; Microtubules; Nocodazole; Osteosarcoma; Paclitaxel; Tumor Cells, Cultured; Vinblastine

1997
Microtubules suppress actomyosin-based cortical flow in Xenopus oocytes.
    Journal of cell science, 1997, Volume: 110 ( Pt 16)

    Topics: Actins; Actomyosin; Animals; Cell Division; Female; Intermediate Filaments; Keratins; Microscopy, Fluorescence; Microtubules; Models, Biological; Nocodazole; Oocytes; Paclitaxel; Tetradecanoylphorbol Acetate; Tubulin; Xenopus laevis

1997
Neonatal rat cardiomyocytes possess a large population of stable microtubules that is enriched in post-translationally modified subunits.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:10

    Topics: Animals; Animals, Newborn; Calcium; Cold Temperature; Microtubules; Myocardium; Nocodazole; Paclitaxel; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Tubulin

1997
Guidance of CNS growth cones by substratum grooves and ridges: effects of inhibitors of the cytoskeleton, calcium channels and signal transduction pathways.
    Journal of cell science, 1997, Volume: 110 ( Pt 23)

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytochalasin B; Cytoskeleton; Embryo, Mammalian; Embryo, Nonmammalian; Enzyme Inhibitors; Gadolinium; GTP-Binding Proteins; Hippocampus; Indoles; Isoquinolines; Maleimides; Microtubules; Neurites; Neurons; Nocodazole; Paclitaxel; Pertussis Toxin; Protein Kinase Inhibitors; Rats; Spinal Cord; Staurosporine; Sulfonamides; Virulence Factors, Bordetella; Xenopus laevis

1997
Rapid, microtubule-dependent fluctuations of the cell margin.
    Journal of cell science, 1997, Volume: 110 ( Pt 24)

    Topics: Animals; Cell Movement; Chick Embryo; Demecolcine; Microtubules; Nocodazole; Paclitaxel

1997
Microtubule organization and chromatin configurations in hamster oocytes during fertilization and parthenogenetic activation, and after insemination with human sperm.
    Biology of reproduction, 1997, Volume: 57, Issue:5

    Topics: Animals; Antineoplastic Agents; Chromatin; Cricetinae; Diagnostic Imaging; Female; Fertilization; Germ Cells; Humans; Insemination; Male; Mesocricetus; Microscopy, Confocal; Microtubules; Mitosis; Nocodazole; Oocytes; Paclitaxel; Parthenogenesis; Spermatozoa; Zygote

1997
The distribution and requirements of microtubules and microfilaments during fertilization and parthenogenesis in pig oocytes.
    Journal of reproduction and fertility, 1997, Volume: 111, Issue:1

    Topics: Actin Cytoskeleton; Animals; Antineoplastic Agents; Cleavage Stage, Ovum; Cytochalasin D; Cytoskeleton; Electric Stimulation; Female; Fertilization in Vitro; Male; Microscopy, Confocal; Microtubules; Nocodazole; Oocytes; Paclitaxel; Parthenogenesis; Spermatozoa; Swine

1997
The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells.
    Cancer research, 1997, Nov-15, Volume: 57, Issue:22

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Caffeine; CDC2 Protein Kinase; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; Doxorubicin; Electrophoresis, Polyacrylamide Gel; G1 Phase; G2 Phase; Humans; Mice; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Protein Kinases; Threonine; Tumor Cells, Cultured; Tyrosine

1997
Extracellular matrix (ECM) and cytoskeletal modulation of cellular radiosensitivity.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:6

    Topics: Actin Cytoskeleton; Animals; Antineoplastic Agents; Cell Adhesion; Cell Line, Transformed; Collagen; Cricetinae; Cricetulus; Cytochalasin B; Cytoskeleton; Extracellular Matrix; Fibroblasts; Gels; Humans; Microtubules; Nocodazole; Paclitaxel; Phalloidine; Plastics; Radiation Tolerance; Rats; Trypsin

1997
Translocation of myelin basic protein mRNA in oligodendrocytes requires microtubules and kinesin.
    Cell motility and the cytoskeleton, 1997, Volume: 38, Issue:4

    Topics: Actin Cytoskeleton; Animals; Biological Transport; Cells, Cultured; Cytochalasin B; Kinesins; Mice; Microtubules; Myelin Basic Protein; Nocodazole; Oligodendroglia; Oligonucleotides, Antisense; Paclitaxel; Rats; Rats, Sprague-Dawley; RNA, Messenger

1997
CLIP-115, a novel brain-specific cytoplasmic linker protein, mediates the localization of dendritic lamellar bodies.
    Neuron, 1997, Volume: 19, Issue:6

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; COS Cells; Dendrites; Humans; Male; Microtubule-Associated Proteins; Microtubules; Molecular Sequence Data; Neoplasm Proteins; Nerve Tissue Proteins; Neurons; Nocodazole; Olivary Nucleus; Paclitaxel; Rats; Rats, Wistar; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transfection

1997
The major soluble tubulins are found in mega dalton (MDa) fractions in fully-grown oocytes and eggs but not in brain of the frog, Rana pipiens.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1997, Volume: 118, Issue:2

    Topics: Animals; Blotting, Western; Brain; Chromatography, Gel; Female; Molecular Weight; Nocodazole; Oocytes; Organ Specificity; Ovum; Paclitaxel; Progesterone; Rana pipiens; Rats; Solubility; Tubulin

1997
Effects of some cytoskeleton inhibitors on ooplasmic segregation in the Nereis virens egg.
    The International journal of developmental biology, 1997, Volume: 41, Issue:6

    Topics: Actins; Animals; Cell Compartmentation; Colchicine; Cytochalasin B; Cytoskeleton; Microtubules; Nocodazole; Ovum; Paclitaxel; Polychaeta

1997
A major 170 kDa protein associated with bovine adrenal medulla microtubules: a member of the centrosomin family?
    FEBS letters, 1997, Dec-29, Volume: 420, Issue:2-3

    Topics: Adrenal Medulla; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Blotting, Western; Cattle; Cells, Cultured; Chromatography; Drosophila Proteins; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; HeLa Cells; Homeodomain Proteins; Humans; Immunohistochemistry; Mass Spectrometry; Microscopy, Video; Microtubule-Associated Proteins; Nocodazole; Paclitaxel; Sequence Analysis

1997
Microtubule coils versus the surface membrane cytoskeleton in maintenance and restoration of platelet discoid shape.
    The American journal of pathology, 1998, Volume: 152, Issue:2

    Topics: Actins; Blood Platelets; Cell Membrane; Colchicine; Cold Temperature; Cytochalasin B; Cytoskeleton; Hot Temperature; Humans; Microtubules; Nocodazole; Paclitaxel; Reference Values; Temperature; Vincristine

1998
Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways.
    The Journal of biological chemistry, 1998, Feb-27, Volume: 273, Issue:9

    Topics: Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Colchicine; Dose-Response Relationship, Drug; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Microtubules; Mitogen-Activated Protein Kinases; Models, Biological; Nocodazole; Paclitaxel; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-jun; ras Proteins; Regulatory Sequences, Nucleic Acid; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Vinca Alkaloids

1998
The microtubule depolymerizing drugs nocodazole and colchicine inhibit the uptake of Listeria monocytogenes by P388D1 macrophages.
    FEMS microbiology letters, 1998, Mar-01, Volume: 160, Issue:1

    Topics: Actins; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Colchicine; Cytoskeleton; Dendritic Cells; Humans; Leukemia P388; Listeria monocytogenes; Macrophages; Mice; Microtubules; Nocodazole; Paclitaxel; Phagocytosis

1998
Organotypic spinal cord culture in serum-free fibrin gel: a new approach to study three-dimensional neurite outgrowth and of neurotoxicity testing: Effects of modulating the actin and tubulin dynamics and protein kinase activities.
    Journal of neuroscience methods, 1997, Dec-30, Volume: 78, Issue:1-2

    Topics: Actins; Animals; Aprotinin; Azepines; Chick Embryo; Cytochalasin D; Densitometry; Diglycerides; Enzyme Inhibitors; Fibrin; Gels; Indoles; Neurites; Neurotoxins; Nocodazole; Organ Culture Techniques; Paclitaxel; Protein Kinases; Spinal Cord; Tetraethyl Lead; Tubulin

1997
Serine-70 is one of the critical sites for drug-induced Bcl2 phosphorylation in cancer cells.
    Cancer research, 1998, Apr-15, Volume: 58, Issue:8

    Topics: Alanine; Antineoplastic Agents; Apoptosis; Depsipeptides; Humans; Mutagenesis, Site-Directed; Nocodazole; Okadaic Acid; Oligopeptides; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Serine; Tumor Cells, Cultured

1998
Activation of the metaphase checkpoint and an apoptosis programme in the early zebrafish embryo, by treatment with the spindle-destabilising agent nocodazole.
    Zygote (Cambridge, England), 1997, Volume: 5, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-2-Associated X Protein; Blastocyst; Calcimycin; Cell Nucleus; Cleavage Stage, Ovum; Cysteine Proteinase Inhibitors; DNA Fragmentation; Epithelial Cells; Gastrula; Genes, bcl-2; Ionophores; Metaphase; Microtubules; Nocodazole; Oligopeptides; Paclitaxel; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Signal Transduction; Spindle Apparatus; Zebrafish

1997
Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase.
    Molecular and cellular biology, 1998, Volume: 18, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Caspases; Cyclic AMP-Dependent Protein Kinases; Cysteine Endopeptidases; DNA Damage; Enzyme Activation; Female; Humans; Male; Microtubules; Nocodazole; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Cells, Cultured; Vincristine

1998
Effect of microtubule disruption on cell adhesion and spreading.
    Biochemical and biophysical research communications, 1998, May-29, Volume: 246, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Adhesion; Cell Size; Docetaxel; Dose-Response Relationship, Drug; Humans; Integrins; Microtubules; Neoplasm Metastasis; Nocodazole; Paclitaxel; Taxoids; Tumor Cells, Cultured; Vinblastine; Vinorelbine

1998
Microtubules and intracellular traffic of secretory proteins in rat extraorbital lacrimal glands.
    Advances in experimental medicine and biology, 1998, Volume: 438

    Topics: Animals; Anti-Bacterial Agents; Brefeldin A; Carbon Radioisotopes; Cyclopentanes; Docetaxel; Eye Proteins; Galactose; Glycoproteins; Golgi Apparatus; In Vitro Techniques; Kinetics; Lacrimal Apparatus; Leucine; Macrolides; Male; Microtubules; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Taxoids; Time Factors; Tritium

1998
The interrelationship between selective tau phosphorylation and microtubule association.
    Brain research, 1998, Jul-06, Volume: 798, Issue:1-2

    Topics: Amino Acid Sequence; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Humans; Lithium; Microtubules; Nocodazole; Okadaic Acid; Paclitaxel; Phosphodiesterase Inhibitors; Phosphorylation; Pyrrolidinones; Rolipram; tau Proteins; Tumor Cells, Cultured

1998
Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.
    The Journal of biological chemistry, 1998, Jul-24, Volume: 273, Issue:30

    Topics: Antineoplastic Agents; Apoptosis; CDC28 Protein Kinase, S cerevisiae; Cyclin B; Cyclin B1; Enzyme Activation; Enzyme Inhibitors; Female; Genistein; HeLa Cells; Humans; Mitosis; Nocodazole; Okadaic Acid; Paclitaxel; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tumor Cells, Cultured

1998
Mechanical interactions among cytoskeletal filaments.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:1

    Topics: Acrylamide; Acrylamides; Actin Cytoskeleton; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Biomechanical Phenomena; Cattle; Cells, Cultured; Cytochalasin D; Cytological Techniques; Cytoskeleton; Drug Synergism; Endothelium; Intermediate Filaments; Microtubules; Nocodazole; Paclitaxel; Stress, Mechanical; Viscosity

1998
Microtubule disruption potentiates phenylephrine-induced vasoconstriction in rat mesenteric arterial bed.
    European journal of pharmacology, 1998, Jun-12, Volume: 351, Issue:1

    Topics: Animals; Endothelium, Vascular; Mesenteric Arteries; Mice; Mice, Inbred BALB C; Microtubules; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nocodazole; Paclitaxel; Phenylephrine; Rats; Rats, Sprague-Dawley; Signal Transduction; Structure-Activity Relationship; Vasoconstriction; Vasoconstrictor Agents

1998
Taxanes propagate apoptosis via two cell populations with distinctive cytological and molecular traits.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1998, Volume: 9, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspases; CDC2 Protein Kinase; Cell Cycle; Cyclin B; Cyclin B1; DNA Fragmentation; Docetaxel; Enzyme Activation; Flow Cytometry; Humans; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Microtubules; Mitogen-Activated Protein Kinase 1; Nocodazole; Paclitaxel; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Taxoids; ZAP-70 Protein-Tyrosine Kinase

1998
Disruption of endothelial microfilaments selectively reduces the transendothelial migration of monocytes.
    Experimental cell research, 1998, Aug-25, Volume: 243, Issue:1

    Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cells, Cultured; Coculture Techniques; Colchicine; Culture Media, Conditioned; Cytochalasin B; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Microscopy, Fluorescence; Monocytes; Nocodazole; Paclitaxel; Protein Kinase C; Sulfonamides; Thiazoles; Thiazolidines; Trifluoperazine; Tumor Necrosis Factor-alpha

1998
CD95-mediated apoptosis: no variation in cellular sensitivity during cell cycle progression.
    FEBS letters, 1998, Aug-07, Volume: 432, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Aphidicolin; Apoptosis; Camptothecin; Cell Cycle; Cell Death; Cisplatin; Culture Media, Serum-Free; Doxorubicin; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Gene Expression; HeLa Cells; Humans; Hydroxyurea; Jurkat Cells; Membrane Glycoproteins; Nimustine; Nocodazole; Paclitaxel; Sensitivity and Specificity; Teniposide; Tumor Cells, Cultured; Vincristine

1998
Use of drugs to study role of microtubule assembly dynamics in living cells.
    Methods in enzymology, 1998, Volume: 298

    Topics: Alkaloids; Antineoplastic Agents; Biopolymers; Cell Line; Colchicine; Drug Synergism; Microtubules; Molecular Weight; Nocodazole; Paclitaxel; Podophyllotoxin; Tubulin; Vinblastine

1998
Regulation of parathyroid hormone-related protein expression in a canine squamous carcinoma cell line by colchicine.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1998, Volume: 50, Issue:4-6

    Topics: Animals; Blotting, Northern; Carcinoma, Squamous Cell; Colchicine; Dogs; Epidermal Growth Factor; Gene Expression Regulation; Luciferases; Lumicolchicines; Neoplasm Proteins; Nocodazole; Paclitaxel; Parathyroid Hormone-Related Protein; Proteins; Radioimmunoassay; RNA, Messenger; Transcription, Genetic; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured; Vinblastine

1998
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease.
    The Journal of cell biology, 1998, Nov-02, Volume: 143, Issue:3

    Topics: Alzheimer Disease; Animals; Biological Transport; Cell Size; Centrosome; CHO Cells; Cricetinae; Docetaxel; Dyneins; Endoplasmic Reticulum; Gene Expression; Intermediate Filament Proteins; Kinesins; Microinjections; Mitochondria; Nocodazole; Paclitaxel; tau Proteins; Taxoids; Transferrin; Tumor Cells, Cultured

1998
Dynamics of axonal microtubules regulate the topology of new membrane insertion into the growing neurites.
    The Journal of cell biology, 1998, Nov-16, Volume: 143, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Axonal Transport; Biological Transport; Carbocyanines; Cell Membrane; Diffusion; Exocytosis; Fluorescent Dyes; Lipid Metabolism; Microtubules; Neurites; Nocodazole; Paclitaxel; Staining and Labeling; Synaptic Vesicles; Vinblastine; Xenopus

1998
Relationship between microtubule dynamics and lamellipodium formation revealed by direct imaging of microtubules in cells treated with nocodazole or taxol.
    Cell motility and the cytoskeleton, 1998, Volume: 41, Issue:4

    Topics: Animals; Cell Adhesion; Cell Line; Cell Movement; Dose-Response Relationship, Drug; Image Processing, Computer-Assisted; Microtubules; Nocodazole; Paclitaxel; Tyrosine

1998
Malignant transformation alters intracellular trafficking of lysosomal cathepsin D in human breast epithelial cells.
    Pathology oncology research : POR, 1998, Volume: 4, Issue:4

    Topics: Animals; Antigens, CD; Biological Transport; Breast; Cathepsin D; Cell Line, Transformed; Cell Transformation, Neoplastic; Cytochalasin D; Epithelial Cells; Female; Fibrocystic Breast Disease; Humans; Immunoglobulin G; Lysosomal Membrane Proteins; Lysosomes; Male; Membrane Glycoproteins; Microscopy, Confocal; Microscopy, Fluorescence; Microtubules; Nocodazole; Oncogene Protein p21(ras); Paclitaxel; Proto-Oncogene Proteins p21(ras); Rabbits; Rats; Recombinant Fusion Proteins; Transfection

1998
The nucleolar phosphoprotein B23 redistributes in part to the spindle poles during mitosis.
    Journal of cell science, 1999, Volume: 112 ( Pt 4)

    Topics: Animals; Antigens, Nuclear; Autoantigens; Cell Cycle Proteins; Cell Division; Cell Line; Cell Nucleolus; Cell-Free System; HeLa Cells; Humans; Macropodidae; Microtubules; Mitosis; Nocodazole; Nuclear Matrix-Associated Proteins; Nuclear Proteins; Nucleolus Organizer Region; Nucleophosmin; Paclitaxel; Phosphoproteins; Phosphorylation; Protein Isoforms; Rats; Spindle Apparatus

1999
Role for microtubules in centrosome doubling in Chinese hamster ovary cells.
    Cell motility and the cytoskeleton, 1999, Volume: 42, Issue:1

    Topics: Animals; Centrosome; CHO Cells; Cricetinae; Dynactin Complex; Dyneins; Hydroxyurea; Immunoblotting; In Vitro Techniques; Microscopy, Electron; Microtubule-Associated Proteins; Microtubules; Mitosis; Nocodazole; Paclitaxel; Spindle Apparatus; Time Factors; Tubulin

1999
Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells.
    Oncogene, 1999, Jan-14, Volume: 18, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Colchicine; Egtazic Acid; Enzyme Activation; Humans; Microtubules; Nocodazole; Paclitaxel; Podophyllotoxin; Tumor Cells, Cultured; Vincristine

1999
Shc dominant negative disrupts cell cycle progression in both G0-G1 and G2-M of ErbB2-positive breast cancer cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1999, Volume: 10, Issue:1

    Topics: Breast; Breast Neoplasms; Cell Cycle; Epithelial Cells; Female; G1 Phase; G2 Phase; Humans; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Receptor, ErbB-2; Resting Phase, Cell Cycle; src Homology Domains; Stem Cells; Tumor Cells, Cultured; Tyrosine

1999
EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle.
    Oncogene, 1998, Dec-31, Volume: 17, Issue:26

    Topics: Adenomatous Polyposis Coli Protein; Animals; Antineoplastic Agents; Blotting, Western; Cell Cycle; Cells, Cultured; COS Cells; Cricetinae; Cytoskeletal Proteins; Cytoskeleton; DNA-Binding Proteins; Fluorescent Antibody Technique; Humans; Microtubule-Associated Proteins; Microtubules; Nocodazole; Paclitaxel

1998
Microtubule-dependent plus- and minus end-directed motilities are competing processes for nuclear targeting of adenovirus.
    The Journal of cell biology, 1999, Feb-22, Volume: 144, Issue:4

    Topics: Adenoviruses, Human; Animals; Base Sequence; Cell Line; Cell Nucleus; Chlorocebus aethiops; Cytosol; DNA Primers; Dynactin Complex; Dyneins; Fluorescent Dyes; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Molecular Motor Proteins; Movement; Nocodazole; Paclitaxel; Virus Replication

1999
CLIP-170 highlights growing microtubule ends in vivo.
    Cell, 1999, Feb-19, Volume: 96, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Chlorocebus aethiops; Gene Expression; Green Fluorescent Proteins; HeLa Cells; Humans; Indicators and Reagents; Kinetics; Luminescent Proteins; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Neoplasm Proteins; Nocodazole; Paclitaxel; Recombinant Fusion Proteins; Vero Cells

1999
Rapid aggregate formation of the huntingtin N-terminal fragment carrying an expanded polyglutamine tract.
    Biochemical and biophysical research communications, 1999, Mar-16, Volume: 256, Issue:2

    Topics: Animals; Blotting, Western; Cell Nucleus; COS Cells; Cycloheximide; Cytochalasin D; Cytoplasm; Exons; Humans; Huntingtin Protein; Huntington Disease; Molecular Weight; Nerve Tissue Proteins; Nocodazole; Nuclear Proteins; Paclitaxel; Peptide Fragments; Peptides; Protein Binding; Recombinant Fusion Proteins; Time Factors; Transfection; Tunicamycin

1999
Different contributions of microtubule dynamics and transport to the growth of axons and collateral sprouts.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, May-15, Volume: 19, Issue:10

    Topics: Animals; Axons; Biological Transport; Biopolymers; Cells, Cultured; Chick Embryo; Cytoskeleton; Dendrites; Microtubules; Nocodazole; Paclitaxel

1999
Differential localization of protein kinase A type II isozymes in the Golgi-centrosomal area.
    Experimental cell research, 1999, May-25, Volume: 249, Issue:1

    Topics: Antibodies, Monoclonal; Bone Neoplasms; Cell Line, Transformed; Cells, Cultured; Centrosome; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Female; Fibroblasts; Golgi Apparatus; Granulosa Cells; Humans; Isoenzymes; Keratinocytes; Lymphocytes; Macrophages; Microscopy, Confocal; Microscopy, Fluorescence; Microtubules; Neoplasm Proteins; Nocodazole; Osteosarcoma; Paclitaxel; Second Messenger Systems; Subcellular Fractions; Trophoblasts; Tumor Cells, Cultured

1999
Theileria parva: sporozoite entry into bovine lymphocytes is not dependent on the parasite cytoskeleton.
    Experimental parasitology, 1999, Volume: 92, Issue:1

    Topics: Actins; Animals; Cattle; Cytochalasin D; Cytoskeleton; Host-Parasite Interactions; Lymphocytes; Nocodazole; Okadaic Acid; Paclitaxel; Theileria parva; Theileriasis; Ticks

1999
Neuronal cytoskeletal alterations evoked by a platelet-activating factor (PAF) analogue.
    Cell motility and the cytoskeleton, 1999, Volume: 43, Issue:2

    Topics: Actins; Animals; Cells, Cultured; Cytochalasin D; Cytoskeleton; Fluorescent Antibody Technique, Indirect; Microtubules; Mitochondria; Neurites; Neurons; Nocodazole; Paclitaxel; Phospholipid Ethers; Platelet Activating Factor; Polymers; Rats; Rats, Sprague-Dawley

1999
Bistratene A induces a microtubule-dependent block in cytokinesis and altered stathmin expression in HL60 cells.
    Biochemical and biophysical research communications, 1999, Jun-24, Volume: 260, Issue:1

    Topics: Acetamides; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Count; Cell Division; Dose-Response Relationship, Drug; Ethers, Cyclic; Growth Inhibitors; HL-60 Cells; Humans; Microtubule Proteins; Microtubules; Nocodazole; Paclitaxel; Phosphoproteins; Pyrans; Spiro Compounds; Stathmin; Time Factors; Tubulin

1999
Taxol, vincristine or nocodazole induces lethality in G1-checkpoint-defective human astrocytoma U373MG cells by triggering hyperploid progression.
    Carcinogenesis, 1999, Volume: 20, Issue:7

    Topics: Astrocytoma; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; Fibroblasts; Flow Cytometry; Humans; Hydroxyurea; Karyotyping; Microtubule-Associated Proteins; Nocodazole; Paclitaxel; Phosphorylation; Polyploidy; Retinoblastoma Protein; Thymidine; Tumor Cells, Cultured; Tumor Suppressor Proteins; Vincristine

1999
Mapmodulin, cytoplasmic dynein, and microtubules enhance the transport of mannose 6-phosphate receptors from endosomes to the trans-golgi network.
    Molecular biology of the cell, 1999, Volume: 10, Issue:7

    Topics: Animals; Biological Transport; Carrier Proteins; Cattle; CHO Cells; Cricetinae; Cytoplasm; Dynactin Complex; Dyneins; Endosomes; Golgi Apparatus; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microtubule-Associated Proteins; Microtubules; Nocodazole; Nuclear Proteins; Paclitaxel; Proteins; Receptor, IGF Type 2; Recombinant Proteins; RNA-Binding Proteins; Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins; tau Proteins; Vesicular Transport Proteins

1999
Induced differentiation in HT29, a human colon adenocarcinoma cell line.
    Journal of cell science, 1999, Volume: 112 ( Pt 16)

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cadherins; Cell Differentiation; Cell Polarity; Colchicine; Colforsin; Cytochalasin D; Cytoplasm; Fluorescent Antibody Technique; Freeze Fracturing; HT29 Cells; Humans; Microscopy, Electron; Microscopy, Electron, Scanning; Microtubules; Microvilli; Nocodazole; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Tight Junctions

1999
ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation.
    Molecular medicine (Cambridge, Mass.), 1999, Volume: 5, Issue:7

    Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Carrier Proteins; Caspase 3; Caspase Inhibitors; Caspases; Cerebellum; Colchicine; Cyclosporine; Cysteine Proteinase Inhibitors; Deoxyglucose; Dizocilpine Maleate; Energy Metabolism; Enzyme Activation; Enzyme Inhibitors; Glutathione; Mice; Mice, Inbred BALB C; Microfilament Proteins; Microtubules; Neurons; Neuroprotective Agents; Nitroso Compounds; Nocodazole; Oligopeptides; Paclitaxel; Potassium; Protein Biosynthesis; S-Nitrosoglutathione; Tacrolimus; Verapamil

1999
Modulation of urokinase-type plasminogen activator and metalloproteinase activities in cultured mouse mammary-carcinoma cells: enhancement by paclitaxel and inhibition by nocodazole.
    International journal of cancer, 1999, Oct-08, Volume: 83, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Collagenases; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Mice, Inbred BALB C; Microtubules; Nocodazole; Paclitaxel; Secretory Rate; Tubulin; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1999
Microtubule targeting of substrate contacts promotes their relaxation and dissociation.
    The Journal of cell biology, 1999, Sep-06, Volume: 146, Issue:5

    Topics: Actins; Animals; Cell Adhesion; Cell Division; Cell Line; Cell Polarity; Cell Size; Fibroblasts; Goldfish; GTP-Binding Proteins; Intracellular Signaling Peptides and Proteins; Microtubules; Myosin-Light-Chain Kinase; Myosins; Nocodazole; Paclitaxel; Polymers; Protein Serine-Threonine Kinases; Pseudopodia; rac GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Transfection; Tubulin; Vinculin

1999
Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts.
    Nature cell biology, 1999, Volume: 1, Issue:1

    Topics: 3T3 Cells; Actins; Animals; Cell Movement; Kinetics; Mice; Microtubules; Nocodazole; Paclitaxel; rac1 GTP-Binding Protein

1999
Tubulin polyglutamylase: isozymic variants and regulation during the cell cycle in HeLa cells.
    Journal of cell science, 1999, Volume: 112 ( Pt 23)

    Topics: Animals; Brain; Cell Cycle; Cell Division; Centrioles; Docetaxel; G2 Phase; Gene Expression Regulation, Enzymologic; Genetic Variation; HeLa Cells; Humans; Hydroxyurea; Isoenzymes; Mice; Nocodazole; Paclitaxel; Peptide Synthases; Polyglutamic Acid; Spindle Apparatus; Taxoids; Tubulin

1999
Premeiotic aster as a device to anchor the germinal vesicle to the cell surface of the presumptive animal pole in starfish oocytes.
    Developmental biology, 2000, Feb-15, Volume: 218, Issue:2

    Topics: Animals; Cell Membrane; Centrifugation; Fluorescent Antibody Technique; Meiosis; Microscopy, Confocal; Nocodazole; Oocytes; Paclitaxel; Starfish

2000
The nuclear/mitotic apparatus protein NuMA is a component of the somatodendritic microtubule arrays of the neuron.
    Journal of neurocytology, 1998, Volume: 27, Issue:12

    Topics: Animals; Antigens, Nuclear; Axons; Bucladesine; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Coculture Techniques; Cytochalasin B; Dendrites; Embryo, Mammalian; HeLa Cells; Hippocampus; Humans; Kinetics; Microtubules; Neuroblastoma; Neurons; Nocodazole; Nuclear Matrix-Associated Proteins; Nuclear Proteins; Paclitaxel; Rats; Spindle Apparatus; Sympathetic Nervous System; Tumor Cells, Cultured

1998
Nocodazole, vinblastine and taxol at low concentrations affect fibroblast locomotion and saltatory movements of organelles.
    Membrane & cell biology, 1999, Volume: 13, Issue:1

    Topics: Animals; Cell Movement; Chlorocebus aethiops; Cytoskeleton; Dose-Response Relationship, Drug; Fibroblasts; Microtubules; Nocodazole; Organelles; Paclitaxel; Vero Cells; Vinblastine

1999
The role of microtubules in the regulation of proteoglycan synthesis in chondrocytes under hydrostatic pressure.
    Archives of biochemistry and biophysics, 2000, Feb-15, Volume: 374, Issue:2

    Topics: Animals; Cartilage, Articular; Cattle; Cells, Cultured; Chondroitin Sulfates; Disaccharides; Golgi Apparatus; Hydrostatic Pressure; Kinetics; Microtubules; Nocodazole; Paclitaxel; Proteoglycans; Sulfates; Sulfur Radioisotopes; Tubulin

2000
Microtubule binding to Smads may regulate TGF beta activity.
    Molecular cell, 2000, Volume: 5, Issue:1

    Topics: Activin Receptors, Type I; Animals; Aorta; Cell Line; Cells, Cultured; Coronary Vessels; DNA-Binding Proteins; Endothelium, Vascular; Gene Expression Regulation; HeLa Cells; Humans; Mice; Microtubules; Nocodazole; Oligodeoxyribonucleotides, Antisense; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad4 Protein; Trans-Activators; Transcription, Genetic; Transforming Growth Factor beta

2000
Microtubules, but not actin filaments, drive daughter cell budding and cell division in Toxoplasma gondii.
    Journal of cell science, 2000, Volume: 113 ( Pt 7)

    Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcimycin; Cell Division; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dinitrobenzenes; Fibroblasts; Growth Inhibitors; Humans; Ionophores; Microscopy, Electron; Microtubules; Nocodazole; Organelles; Paclitaxel; Sulfanilamides; Thiazoles; Thiazolidines; Toxoplasma

2000
Vesicle-mediated phosphatidylcholine reapposition to the plasma membrane following hormone-induced phospholipase D activation.
    Experimental cell research, 2000, Apr-10, Volume: 256, Issue:1

    Topics: Acrylamide; Androstadienes; Animals; Arginine Vasopressin; Brefeldin A; Cell Line; Cell Membrane; Cytochalasin B; Diphenylhexatriene; Enzyme Activation; Exocytosis; Fluorescent Dyes; Kinetics; Membrane Lipids; Muscle, Skeletal; Nocodazole; Paclitaxel; Phosphatidylcholines; Phospholipase D; Rats; Wortmannin; Zinc

2000
Glutamate-induced changes in the pattern of hippocampal dendrite outgrowth: a role for calcium-dependent pathways and the microtubule cytoskeleton.
    Journal of neurobiology, 2000, Volume: 43, Issue:2

    Topics: Antineoplastic Agents; Calcium; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Cytoskeleton; Dendrites; Dipeptides; Enzyme Inhibitors; Fluoresceins; Glutamic Acid; Glycoproteins; Growth Cones; Hippocampus; Imidazoles; Microscopy, Fluorescence; Microtubule Proteins; Microtubules; Neurons; Nocodazole; Paclitaxel

2000
Beating rate of isolated neonatal cardiomyocytes is regulated by the stable microtubule subset.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:5

    Topics: Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Heart Rate; Microtubules; Myocardial Contraction; Myocardium; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Tubulin; Tubulin Modulators; Tyrosine

2000
Spindle formation and dynamics of gamma-tubulin and nuclear mitotic apparatus protein distribution during meiosis in pig and mouse oocytes.
    Biology of reproduction, 2000, Volume: 62, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Cycle Proteins; Female; Fluorescent Antibody Technique; Meiosis; Mice; Microscopy, Confocal; Mitosis; Nocodazole; Nuclear Proteins; Oocytes; Paclitaxel; Species Specificity; Spindle Apparatus; Swine; Tubulin

2000
Myeloid cell leukemia 1 is phosphorylated through two distinct pathways, one associated with extracellular signal-regulated kinase activation and the other with G2/M accumulation or protein phosphatase 1/2A inhibition.
    The Journal of biological chemistry, 2000, Jul-14, Volume: 275, Issue:28

    Topics: Burkitt Lymphoma; Cell Cycle; Cell Survival; Enzyme Activation; Enzyme Inhibitors; G2 Phase; Humans; Marine Toxins; Microtubules; Mitogen-Activated Protein Kinases; Mitosis; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Nocodazole; Okadaic Acid; Oxazoles; Paclitaxel; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vinblastine

2000
Microtubules regulate local Ca2+ spiking in secretory epithelial cells.
    The Journal of biological chemistry, 2000, Jul-21, Volume: 275, Issue:29

    Topics: Animals; Calcium; Cells, Cultured; Colchicine; Dose-Response Relationship, Drug; Epithelial Cells; Mice; Microtubules; Nocodazole; Paclitaxel; Pancreas

2000
Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways.
    The Journal of biological chemistry, 2000, May-19, Volume: 275, Issue:20

    Topics: 2-Methoxyestradiol; Breast; Cell Line; Colchicine; Cyclooxygenase 2; Epithelial Cells; Estradiol; Female; Humans; Isoenzymes; Kinetics; Membrane Proteins; Microtubules; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nocodazole; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Prostaglandin-Endoperoxide Synthases; Transcription, Genetic; Vinblastine; Vincristine

2000
The distribution and requirements of microtubules and microfilaments in bovine oocytes during in vitro maturation.
    Zygote (Cambridge, England), 2000, Volume: 8, Issue:1

    Topics: Actin Cytoskeleton; Animals; Cattle; Chromatin; Cytochalasin B; Female; Fluorescent Antibody Technique; In Vitro Techniques; Meiosis; Microscopy, Confocal; Microtubules; Nocodazole; Oocytes; Paclitaxel

2000
Reorganization of microtubules in the amitotically dividing macronucleus of tetrahymena.
    Cell motility and the cytoskeleton, 2000, Volume: 46, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benomyl; Cell Division; Cell Nucleus; DNA, Protozoan; Fungicides, Industrial; Interphase; Microscopy, Confocal; Microtubules; Nocodazole; Paclitaxel; Tetrahymena pyriformis

2000
Sorting and reorganization of centrosomes during oocyte maturation in the mouse.
    Microscopy research and technique, 2000, Jun-01, Volume: 49, Issue:5

    Topics: Anaphase; Animals; Antigens; Centrosome; Cycloheximide; Cytochalasin D; Dyneins; Female; Gonadotropins; Meiosis; Metaphase; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Microscopy, Scanning Probe; Microtubules; Nocodazole; Oocytes; Paclitaxel; Spindle Apparatus; Time Factors; Tubulin; Vanadates

2000
Modulation of paclitaxel resistance by annexin IV in human cancer cell lines.
    British journal of cancer, 2000, Volume: 83, Issue:1

    Topics: Annexin A4; Blotting, Western; Colchicine; Colonic Neoplasms; DNA, Complementary; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Lung Neoplasms; Neoplasm Proteins; Nocodazole; Paclitaxel; Recombinant Fusion Proteins; Transfection; Tubulin Modulators; Tumor Cells, Cultured

2000
Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration.
    Molecular biology of the cell, 2000, Volume: 11, Issue:9

    Topics: Actins; Animals; Cell Line; Cell Movement; Cytoplasm; Green Fluorescent Proteins; Luminescent Proteins; Melanocytes; Melanoma, Experimental; Mice; Microtubules; Nocodazole; Paclitaxel; Proto-Oncogene Proteins c-kit; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

2000
Microtubule disassembly delays the G2-M transition in vertebrates.
    Current biology : CB, 2000, Sep-07, Volume: 10, Issue:17

    Topics: Animals; Cytochalasin D; Demecolcine; G2 Phase; Microtubules; Mitosis; Nocodazole; Paclitaxel; Rats; Vertebrates

2000
Transient invagination of flagella by Tritrichomonas foetus.
    Parasitology research, 2000, Volume: 86, Issue:9

    Topics: Animals; Cell Membrane; Cold Temperature; Cytochalasin D; Dimethyl Sulfoxide; Endocytosis; Flagella; In Vitro Techniques; Microscopy, Electron; Microscopy, Fluorescence; Models, Animal; Nocodazole; Paclitaxel; Sodium Chloride; Sucrose; Time Factors; Trichomonas

2000
Effects of microtubule disruption on force, velocity, stiffness and [Ca(2+)](i) in porcine coronary arteries.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiogenesis Inhibitors; Animals; Arteries; Calcium; Coronary Vessels; In Vitro Techniques; Intracellular Fluid; Isometric Contraction; Microtubules; Nocodazole; Paclitaxel; Potassium Chloride; Stress, Mechanical; Swine; Vasoconstriction; Vasoconstrictor Agents

2000
Role of microtubules in LPS-induced macrophage inflammatory protein-2 production from rat pneumocytes.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Brefeldin A; Bronchi; Cells, Cultured; Chemokine CXCL2; Chemokines; Colchicine; Endoplasmic Reticulum; Gene Expression; Golgi Apparatus; Lipopolysaccharides; Male; Microtubules; Nocodazole; Paclitaxel; Protein Synthesis Inhibitors; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; RNA, Messenger

2000
Immobilization of the early secretory pathway by a virus glycoprotein that binds to microtubules.
    The EMBO journal, 2000, Dec-01, Volume: 19, Issue:23

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Line; Cell Membrane; Coatomer Protein; COS Cells; Cytoplasm; Cytoskeleton; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Exocytosis; Fluorescent Antibody Technique; Glutathione Transferase; Glycoproteins; Glycoside Hydrolases; Golgi Apparatus; Macaca mulatta; Mannose-Binding Lectins; Membrane Glycoproteins; Membrane Proteins; Microscopy, Confocal; Microtubules; Models, Biological; Nocodazole; Paclitaxel; Plasmids; Precipitin Tests; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; Rotavirus; Time Factors; Transfection; Tubulin; Viral Envelope Proteins; Viral Nonstructural Proteins

2000
Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells.
    Journal of cell science, 2001, Volume: 114, Issue:Pt 2

    Topics: Animals; Bacterial Proteins; Cell Cycle; Cell Line; Colchicine; DNA Replication; DNA, Mitochondrial; Electron Transport Complex IV; G2 Phase; Genes, Reporter; Humans; Intracellular Membranes; Kinetics; Luminescent Proteins; Mammals; Membrane Potentials; Microtubules; Mitochondria; Mitochondria, Liver; Mitosis; Nocodazole; Osteosarcoma; Paclitaxel; Rats; Transfection

2001
Stathmin/Op18 phosphorylation is regulated by microtubule assembly.
    Molecular biology of the cell, 2001, Volume: 12, Issue:2

    Topics: Animals; Cell Nucleus; Centrosome; Enzyme Inhibitors; Female; HeLa Cells; Humans; Interphase; Male; Microtubule Proteins; Microtubules; Nocodazole; Ovum; Paclitaxel; Phosphoproteins; Phosphorylation; Protein Isoforms; Serine; Spermatozoa; Stathmin; Xenopus; Xenopus Proteins

2001
The role of actin filaments and microtubules in hepatocyte spheroid self-assembly.
    Cell motility and the cytoskeleton, 2001, Volume: 48, Issue:3

    Topics: Actins; Albumins; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochalasin D; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Cytoskeleton; Dose-Response Relationship, Drug; Hepatocytes; Liver; Male; Microscopy, Confocal; Microscopy, Electron, Scanning; Microtubules; Models, Biological; Movement; Nocodazole; Nucleic Acid Synthesis Inhibitors; Oxazines; Paclitaxel; Rats; Rats, Sprague-Dawley; Regeneration; Spheroids, Cellular; Steroid Hydroxylases; Time Factors

2001
Association of bovine papillomavirus type 1 with microtubules.
    Virology, 2001, Apr-10, Volume: 282, Issue:2

    Topics: Active Transport, Cell Nucleus; Animals; Blotting, Western; Bovine papillomavirus 1; Capsid; Cattle; Cell Line; Cell Membrane; Cell Nucleus; Cytoplasmic Vesicles; Fluorescent Antibody Technique, Indirect; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel; Protein Binding; Temperature; Tubulin; Virion; Warts

2001
Determination of the net exchange rate of tubulin dimer in steady-state microtubules by fluorescence correlation spectroscopy.
    Biological chemistry, 2001, Volume: 382, Issue:3

    Topics: Animals; Colchicine; Dimerization; Fluorescent Dyes; Microtubules; Nocodazole; Paclitaxel; Rhodamines; Spectrometry, Fluorescence; Tubulin; Vincristine

2001
Nocodazole treatment of CV-1 cells enhances nuclear/perinuclear accumulation of lipid-DNA complexes and increases gene expression.
    Pharmaceutical research, 2001, Volume: 18, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Nucleus; Cells, Cultured; Chlorocebus aethiops; DNA; Gene Expression; Genes, Reporter; Lipid Metabolism; Luciferases; Nocodazole; Paclitaxel; Rhodamines; Subcellular Fractions; Transfection

2001
Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores.
    Molecular biology of the cell, 2001, Volume: 12, Issue:7

    Topics: Animals; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Line; Cell Nucleus; Chromosomal Proteins, Non-Histone; Cytoplasm; Dyneins; Fluorescent Antibody Technique; Kinetochores; Mad2 Proteins; Metaphase; Microtubules; Nocodazole; Paclitaxel; Poly-ADP-Ribose Binding Proteins; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Repressor Proteins; Signal Transduction; Spindle Apparatus

2001
Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2001, Volume: 4, Issue:1

    Topics: Adenoviridae; Antigens, CD; Aphidicolin; Capsid; Carcinoma; Cell Cycle; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Cyclin B; Cyclin B1; Gene Expression; Gene Transfer Techniques; Genetic Vectors; Integrin alphaV; Lung Neoplasms; Nocodazole; Paclitaxel; Receptors, Virus; Transgenes; Tumor Cells, Cultured

2001
The non-catalytic domain of the Xenopus laevis auroraA kinase localises the protein to the centrosome.
    Journal of cell science, 2001, Volume: 114, Issue:Pt 11

    Topics: Amino Acid Sequence; Animals; Aurora Kinases; Catalytic Domain; Cell Cycle Proteins; Cell Extracts; Centrosome; Conserved Sequence; Humans; Male; Mice; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Molecular Sequence Data; Nocodazole; Oocytes; Paclitaxel; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; Sequence Alignment; Sperm Head; Spindle Apparatus; Xenopus laevis; Xenopus Proteins

2001
Identification and characterization of a family of Rab11-interacting proteins.
    The Journal of biological chemistry, 2001, Oct-19, Volume: 276, Issue:42

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Base Sequence; Blotting, Western; Cell Line; Cell Membrane; Cloning, Molecular; Conserved Sequence; DNA, Complementary; Dogs; Expressed Sequence Tags; Gastric Mucosa; Gene Deletion; Gene Library; Genes, Dominant; HeLa Cells; Histamine; Humans; Microscopy, Fluorescence; Molecular Sequence Data; Nocodazole; Paclitaxel; Protein Binding; rab GTP-Binding Proteins; Rabbits; Recombinant Proteins; Sequence Homology, Amino Acid; Two-Hybrid System Techniques

2001
Microtubule reorganization during herpes simplex virus type 1 infection facilitates the nuclear localization of VP22, a major virion tegument protein.
    Journal of virology, 2001, Volume: 75, Issue:18

    Topics: Animals; Antiviral Agents; Cell Fractionation; Cell Nucleus; Chlorocebus aethiops; Cytoplasm; DNA, Viral; Fluorescent Antibody Technique, Indirect; Herpesvirus 1, Human; Humans; Microtubules; Nocodazole; Paclitaxel; Phosphonoacetic Acid; Phosphoproteins; Recombinant Fusion Proteins; Vero Cells; Viral Structural Proteins; Virion

2001
Nocodazole inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes via a microtubule-independent mechanism.
    The Journal of biological chemistry, 2001, Nov-23, Volume: 276, Issue:47

    Topics: 3T3 Cells; Adipocytes; Animals; Antineoplastic Agents; CHO Cells; Cricetinae; Glucose; Glucose Transporter Type 4; Insulin; Mice; Microtubules; Monosaccharide Transport Proteins; Muscle Proteins; Nocodazole; Paclitaxel; Protein Transport

2001
The microtubule cytoskeleton participates in control of beta2 integrin avidity.
    The Journal of biological chemistry, 2001, Nov-30, Volume: 276, Issue:48

    Topics: Animals; Antineoplastic Agents; CD18 Antigens; Cell Adhesion; Cell Aggregation; Cell Line; Cell Line, Transformed; Colchicine; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Gout Suppressants; Humans; Integrins; Macrophages; Mice; Microscopy, Video; Microtubules; Models, Statistical; Nocodazole; Paclitaxel; Paxillin; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine

2001
Damaged microtubules can inactivate BCL-2 by means of the mTOR kinase.
    Oncogene, 2001, Sep-27, Volume: 20, Issue:43

    Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Diploidy; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Flow Cytometry; Humans; Microtubules; Nocodazole; Paclitaxel; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Tumor Suppressor Proteins

2001
Levels of phospholipid metabolites in breast cancer cells treated with antimitotic drugs: a 31P-magnetic resonance spectroscopy study.
    Cancer research, 2001, Oct-15, Volume: 61, Issue:20

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Division; Cell Membrane; Collagen; Doxorubicin; Drug Combinations; G2 Phase; Laminin; Methotrexate; Mitosis; Nocodazole; Nuclear Magnetic Resonance, Biomolecular; Paclitaxel; Phosphatidylcholines; Phospholipids; Phosphorus; Proteoglycans; Tumor Cells, Cultured; Vincristine

2001
Centrosome cohesion is regulated by a balance of kinase and phosphatase activities.
    Journal of cell science, 2001, Volume: 114, Issue:Pt 20

    Topics: Antineoplastic Agents; Aurora Kinases; Cell Cycle; Cell Cycle Proteins; Centrosome; Cyclin-Dependent Kinases; Cyclins; Cytochalasin D; Cytoskeleton; Enzyme Inhibitors; Humans; Marine Toxins; Microtubules; NIMA-Related Kinases; Nocodazole; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Oxazoles; Paclitaxel; Phosphoprotein Phosphatases; Phosphorylation; Polo-Like Kinase 1; Protein Kinases; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Transfection; Tumor Cells, Cultured; Xenopus Proteins

2001
Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin.
    Molecular biology of the cell, 2002, Volume: 13, Issue:1

    Topics: Animals; Antibodies; Cell Compartmentation; Cell Line; Cell Membrane; Centrioles; CHO Cells; Cricetinae; Endocytosis; Fluorescent Antibody Technique; Glutamic Acid; HeLa Cells; Humans; Kinesins; Microscopy, Fluorescence; Microtubules; Nocodazole; Paclitaxel; Protein Transport; Transferrin; Transport Vesicles; Tyrosine

2002
[Involvement of FAK, PI3-K and PKC in cell adhesion induced by microtubule disruption].
    Bulletin du cancer, 2002, Volume: 89, Issue:2

    Topics: Antineoplastic Agents; Cell Adhesion; Focal Adhesion Kinase 2; HT29 Cells; Humans; Microtubules; Nocodazole; Paclitaxel; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein-Tyrosine Kinases; Vinblastine; Vinorelbine

2002
Microtubule involvement in the intracellular dynamics for gene transfection mediated by cationic liposomes.
    Gene therapy, 2001, Volume: 8, Issue:21

    Topics: Animals; Antineoplastic Agents; Cations; Cholestenes; Cholesterol; COS Cells; Gene Expression; Liposomes; Luciferases; Lysosomes; Microscopy, Confocal; Microtubules; Nocodazole; Paclitaxel; Transfection

2001
Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions.
    The Journal of biological chemistry, 2002, May-31, Volume: 277, Issue:22

    Topics: Amino Acid Sequence; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Catalysis; Enzyme Inhibitors; Histone Deacetylase 2; Histone Deacetylases; Histones; Humans; Immunohistochemistry; K562 Cells; Mitosis; Models, Biological; Molecular Sequence Data; Nocodazole; Okadaic Acid; Paclitaxel; Peptides; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Binding; Repressor Proteins; Signal Transduction; Subcellular Fractions; Transcription, Genetic

2002
Microtubule-active agents modify nitric oxide production in pulmonary artery endothelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 282, Issue:6

    Topics: Animals; Antineoplastic Agents; Benzoquinones; Cell Membrane; Cells, Cultured; Citrulline; Cytoskeleton; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; HSP90 Heat-Shock Proteins; Lactams, Macrocyclic; Microtubules; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nocodazole; Paclitaxel; Precipitin Tests; Protein Binding; Pulmonary Artery; Quinones; Swine

2002
Calmodulin-containing substructures of the centrosomal matrix released by microtubule perturbation.
    Journal of cell science, 2002, Jun-01, Volume: 115, Issue:Pt 11

    Topics: Animals; Antineoplastic Agents; Calmodulin; Cell Division; Centrosome; Eukaryotic Cells; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Microtubules; Nocodazole; Paclitaxel; Recombinant Fusion Proteins; Vinblastine

2002
G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells.
    The Journal of clinical investigation, 2002, Volume: 110, Issue:1

    Topics: Breast Neoplasms; Colchicine; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Female; G1 Phase; G2 Phase; Humans; Microtubules; Nocodazole; Paclitaxel; Tumor Cells, Cultured; Vincristine

2002
The effects of oxidative stress and altered intracellular calcium levels on vesicular transport of apoE-EGFP.
    Cell biology international, 2002, Volume: 26, Issue:5

    Topics: Apolipoprotein E2; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Astrocytes; Calcium; Calcium Chloride; Cytoplasmic Vesicles; Endoplasmic Reticulum; Gene Expression; Golgi Apparatus; Green Fluorescent Proteins; Humans; Hydrogen Peroxide; Intracellular Fluid; Luminescent Proteins; Microtubules; Nocodazole; Oxidants; Oxidative Stress; Paclitaxel; Potassium Chloride; Protein Isoforms; Protein Transport; Time Factors; Tumor Cells, Cultured

2002
Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis.
    The Journal of biological chemistry, 2002, Oct-04, Volume: 277, Issue:40

    Topics: Anthracenes; Apoptosis; CDC2 Protein Kinase; Cell Cycle; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; G2 Phase; HeLa Cells; Humans; Kinetics; Mitosis; Nocodazole; Paclitaxel; Perylene; Photochemotherapy; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Vinblastine

2002
Correlations between the functional integrity of the endoplasmic reticulum and polarized Ca2+ signalling in mouse lacrimal acinar cells: a role for inositol 1,3,4,5-tetrakisphosphate.
    The Biochemical journal, 2002, Oct-01, Volume: 367, Issue:Pt 1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Calcium; Endoplasmic Reticulum; Inositol Phosphates; Lacrimal Apparatus; Male; Mice; Models, Biological; Nocodazole; Paclitaxel; Patch-Clamp Techniques; Signal Transduction; Spectrometry, Fluorescence; Time Factors

2002
Different modes of NF-kappaB/Rel activation in pancreatic lobules.
    American journal of physiology. Gastrointestinal and liver physiology, 2002, Volume: 283, Issue:2

    Topics: Animals; Ceruletide; Dose-Response Relationship, Drug; Enzyme Activation; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; Kinetics; Male; Microtubules; NF-kappa B; NF-kappa B p50 Subunit; Nocodazole; Oxidants; Paclitaxel; Phosphorylation; Polymers; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine

2002
Microtubule reconfiguration during axonal retraction induced by nitric oxide.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Jul-15, Volume: 22, Issue:14

    Topics: Animals; Antineoplastic Agents; Axons; Cells, Cultured; Chick Embryo; Cytoskeleton; Ganglia, Spinal; Hydrazines; Microscopy, Fluorescence; Microtubules; Neurons; Nitric Oxide; Nitric Oxide Donors; Nocodazole; Paclitaxel; Tubulin; Tyrosine

2002
Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Aug-06, Volume: 99, Issue:16

    Topics: Adenoviruses, Human; Apoptosis; Biological Transport; Cell Nucleus; Colchicine; Doxorubicin; Epothilones; HeLa Cells; Humans; Macrolides; Microtubules; Nocodazole; Nuclear Proteins; Paclitaxel; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Transcriptional Activation; Tubulin; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vincristine

2002
Characterization of nuclear betaII-tubulin in tumor cells: a possible novel target for taxol.
    Cell motility and the cytoskeleton, 2002, Volume: 53, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Nucleolus; Cell Nucleus; Colchicine; Dimerization; Dose-Response Relationship, Drug; Female; Fluorescent Dyes; Humans; Neoplasms; Nocodazole; Nucleolin; Paclitaxel; Phosphoproteins; Protein Isoforms; Rats; RNA-Binding Proteins; Tubulin; Tumor Cells, Cultured

2002
[Intracellular localization of XCAP-E and pEg7 condensins in normal mitosis and after the treatment inducing artificial changes in structural organization of mitotic chromosomes].
    Tsitologiia, 2002, Volume: 44, Issue:6

    Topics: Animals; Carrier Proteins; Cell Cycle Proteins; Cell Line; Chromosomes; Cytoplasm; Egg Proteins; Hypotonic Solutions; Immunohistochemistry; Mitosis; Nocodazole; Nuclear Proteins; Paclitaxel; Time Factors; Xenopus laevis; Xenopus Proteins

2002
External mechanical strain regulates membrane targeting of Rho GTPases by controlling microtubule assembly.
    American journal of physiology. Cell physiology, 2003, Volume: 284, Issue:3

    Topics: Animals; Cell Adhesion; Cell Membrane; Cytoskeleton; Focal Adhesions; Lysophospholipids; Mechanotransduction, Cellular; Microtubules; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nocodazole; Paclitaxel; rac GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Stress, Mechanical

2003
Hypertonicity-induced projections reflect cell polarity in mouse metaphase II oocytes: involvement of microtubules, microfilaments, and chromosomes.
    Biology of reproduction, 2002, Volume: 67, Issue:6

    Topics: Actin Cytoskeleton; Animals; Blood; Cell Polarity; Cells, Cultured; Chromosomes; Culture Media; Cytochalasin B; Female; Hypertonic Solutions; Metaphase; Mice; Microtubules; Nocodazole; Oocytes; Osmolar Concentration; Paclitaxel; Saline Solution, Hypertonic; Sucrose

2002
Mechanisms of cell positioning during C. elegans gastrulation.
    Development (Cambridge, England), 2003, Volume: 130, Issue:2

    Topics: Actin Cytoskeleton; Actins; Animals; Body Patterning; Bridged Bicyclo Compounds, Heterocyclic; Caenorhabditis elegans; Cell Lineage; Cell Polarity; Chemotaxis; Cytochalasin D; Enzyme Inhibitors; Gastrula; Luminescent Proteins; Models, Biological; Morphogenesis; Nocodazole; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Recombinant Fusion Proteins; Thiazoles; Thiazolidines

2003
Microtubule-dependent regulation of Rho GTPases during internalisation of Yersinia pseudotuberculosis.
    FEBS letters, 2003, Jan-02, Volume: 533, Issue:1-3

    Topics: Biological Transport, Active; cdc42 GTP-Binding Protein; Dynactin Complex; Dyneins; GTP Phosphohydrolases; HeLa Cells; Humans; Microtubule-Associated Proteins; Microtubules; Nocodazole; Oncogene Proteins; Paclitaxel; Proto-Oncogene Proteins c-vav; Recombinant Fusion Proteins; rho GTP-Binding Proteins; Yersinia pseudotuberculosis

2003
Cytoskeletal participation in stimulated secretion and compensatory apical plasma membrane retrieval in lacrimal gland acinar cells.
    Advances in experimental medicine and biology, 2002, Volume: 506, Issue:Pt A

    Topics: Actin Cytoskeleton; Adaptation, Physiological; Animals; beta-N-Acetylhexosaminidases; Carbachol; Cell Membrane; Cytoskeleton; Lacrimal Apparatus; Microtubules; Models, Biological; Nocodazole; Paclitaxel; Rabbits

2002
The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability.
    The Journal of biological chemistry, 2003, May-16, Volume: 278, Issue:20

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; COS Cells; Enzyme Activation; Glutathione; Humans; Immunoblotting; Mice; Microscopy, Fluorescence; Microtubules; Mitogen-Activated Protein Kinases; Nocodazole; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Kinases; Protein Structure, Tertiary; Signal Transduction; Transfection

2003
RNP stress-granule formation is inhibited by microtubule disruption.
    Cell biology international, 2003, Volume: 27, Issue:3

    Topics: Actin Cytoskeleton; Animals; Arsenates; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cytoplasm; Eukaryotic Cells; Microtubules; Nocodazole; Paclitaxel; Reaction Time; Stress, Physiological; Thiazoles; Thiazolidines; Vault Ribonucleoprotein Particles

2003
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint.
    The Journal of cell biology, 2003, Apr-28, Volume: 161, Issue:2

    Topics: Anaphase; Aneugens; Animals; Aurora Kinase B; Aurora Kinases; Cell Cycle Proteins; Chromosome Segregation; Endopeptidases; Eukaryotic Cells; Genes, cdc; HeLa Cells; Humans; Indoles; Kinetochores; Microtubules; Mitosis; Nocodazole; Paclitaxel; Phenotype; Polyploidy; Protein Kinases; Protein Serine-Threonine Kinases; Pyrimidines; RNA, Small Interfering; Separase; Spindle Apparatus; Sulfonamides; Thiones

2003
Cytoskeletal and morphological alterations underlying axonal sprouting after localized transection of cortical neuron axons in vitro.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, May-01, Volume: 23, Issue:9

    Topics: Animals; Axons; Axotomy; Cells, Cultured; Cerebral Cortex; Cytoskeleton; Fluorescent Antibody Technique; Growth Cones; Neurites; Neurons; Nocodazole; Paclitaxel; Rats; Rats, Wistar; tau Proteins; Tubulin

2003
p53 deficiency and defective mitotic checkpoint in proliferating T lymphocytes increase chromosomal instability through aberrant exit from mitotic arrest.
    Journal of leukocyte biology, 2003, Volume: 73, Issue:6

    Topics: Animals; Cell Cycle Proteins; Cells, Cultured; Chromosomes; DNA; Female; Humans; Jurkat Cells; Kinetics; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Knockout; Mitosis; Mutation; Nocodazole; Paclitaxel; Phosphorylation; Polyploidy; Protein Kinases; Protein Serine-Threonine Kinases; Spindle Apparatus; T-Lymphocytes; Tumor Suppressor Protein p53

2003
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells.
    Journal of cell science, 2003, Jul-15, Volume: 116, Issue:Pt 14

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Aurora Kinase B; Aurora Kinases; Cell Cycle; Cell Division; Cell Separation; Centromere; Chromosomal Proteins, Non-Histone; Flow Cytometry; Fluorescent Antibody Technique, Indirect; HeLa Cells; Humans; Immunoblotting; In Situ Nick-End Labeling; Inhibitor of Apoptosis Proteins; Kinetochores; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Mitosis; Neoplasm Proteins; Nocodazole; Oligonucleotides; Paclitaxel; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Survivin; Time Factors; Transfection

2003
Association between mitotic spindle checkpoint impairment and susceptibility to the induction of apoptosis by anti-microtubule agents in human lung cancers.
    The American journal of pathology, 2003, Volume: 163, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Docetaxel; Drug Resistance; Humans; Lung Neoplasms; Microtubules; Mitosis; Nocodazole; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Spindle Apparatus; Taxoids; Tumor Cells, Cultured; Vinblastine; Vinorelbine

2003
Modulation of the expression of connective tissue growth factor by alterations of the cytoskeleton.
    The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45

    Topics: Actins; Amides; Bacterial Proteins; Bacterial Toxins; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Colchicine; Connective Tissue Growth Factor; Cytochalasin D; Cytoskeleton; Fibroblasts; Gene Expression Regulation; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Nocodazole; Paclitaxel; Pyridines; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Stress, Mechanical; Thiazoles; Thiazolidines

2003
Regulation of p120-catenin nucleocytoplasmic shuttling activity.
    Journal of cell science, 2003, Oct-15, Volume: 116, Issue:Pt 20

    Topics: Cadherins; Catenins; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cloning, Molecular; Cytoskeleton; Delta Catenin; HeLa Cells; HT29 Cells; Humans; Microscopy, Fluorescence; Microtubules; Mutation; Nocodazole; Nuclear Localization Signals; Paclitaxel; Phosphoproteins; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein Transport

2003
Disruption of microtubules inhibits cytoplasmic ribonucleoprotein stress granule formation.
    Experimental cell research, 2003, Nov-01, Volume: 290, Issue:2

    Topics: Actins; Animals; Arsenates; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chlorocebus aethiops; Cytoplasmic Granules; Cytoskeleton; Eukaryotic Initiation Factor-3; Fibroblasts; Marine Toxins; Microtubules; Nocodazole; Paclitaxel; Phosphorylation; Prokaryotic Initiation Factor-3; Ribonucleoproteins; Stress Fibers; Thiazoles; Thiazolidines; Vinblastine

2003
Rab11b resides in a vesicular compartment distinct from Rab11a in parietal cells and other epithelial cells.
    Experimental cell research, 2003, Nov-01, Volume: 290, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Compartmentation; Cell Line; Cell Membrane; Cell Polarity; Dogs; Epithelial Cells; Green Fluorescent Proteins; H(+)-K(+)-Exchanging ATPase; Humans; Immunoglobulin A; Kidney; Luminescent Proteins; Mice; Nocodazole; Paclitaxel; Parietal Cells, Gastric; Protein Transport; rab GTP-Binding Proteins; Rabbits; Receptors, Fc; Receptors, Transferrin; Transferrin

2003
Vaults bind directly to microtubules via their caps and not their barrels.
    Cell motility and the cytoskeleton, 2003, Volume: 56, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Fractionation; HeLa Cells; Humans; Microscopy, Fluorescence; Microtubules; Nocodazole; Paclitaxel; Protein Binding; Protein Transport; Rats; Subtilisin; Tubulin; Vault Ribonucleoprotein Particles

2003
The effect of drugs on cell structure of Tritrichomonas foetus.
    Parasitology research, 2004, Volume: 92, Issue:2

    Topics: Animals; Cell Cycle; Colchicine; Flow Cytometry; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel; Protozoan Infections; Tritrichomonas foetus

2004
Glycogen synthase kinase-3 regulates cytoskeleton and translocation of Rac1 in long cellular extensions of human keratinocytes.
    Experimental cell research, 2004, Feb-01, Volume: 293, Issue:1

    Topics: Aminophenols; Cells, Cultured; Colchicine; Cytochalasin D; Cytoskeleton; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Humans; Keratinocytes; Lithium Chloride; Maleimides; Nocodazole; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Pseudopodia; rac1 GTP-Binding Protein; Staurosporine

2004
Transforming growth factor-beta-induced inhibition of myogenesis is mediated through Smad pathway and is modulated by microtubule dynamic stability.
    Circulation research, 2004, Mar-19, Volume: 94, Issue:5

    Topics: Cell Differentiation; Cells, Cultured; DNA-Binding Proteins; Gene Expression Regulation; MEF2 Transcription Factors; Microtubules; Muscle Development; Myoblasts; Myogenic Regulatory Factors; Myogenin; Nocodazole; Paclitaxel; Recombinant Fusion Proteins; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad7 Protein; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1

2004
Genetic evidence for interaction between eta- and beta-tubulins.
    Eukaryotic cell, 2004, Volume: 3, Issue:1

    Topics: Alleles; Amino Acid Sequence; Animals; Cell Division; Cloning, Molecular; Drug Resistance; Genetic Complementation Test; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Nocodazole; Paclitaxel; Paramecium tetraurelia; Phenotype; Protein Binding; Protein Conformation; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Temperature; Tubulin

2004
Aurora B regulates MCAK at the mitotic centromere.
    Developmental cell, 2004, Volume: 6, Issue:2

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Aurora Kinase B; Aurora Kinases; Autoradiography; Cell Cycle; Centromere; CHO Cells; Chromatography, High Pressure Liquid; Chromosomes; Cricetinae; Electrophoresis, Gel, Two-Dimensional; Fluorescence Recovery After Photobleaching; Fluorescent Antibody Technique; Green Fluorescent Proteins; HeLa Cells; Humans; In Vitro Techniques; Kinesins; Kinetochores; Luminescent Proteins; Mitosis; Models, Biological; Mutation; Nocodazole; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Rats; RNA, Small Interfering; Transfection

2004
The cytoskeleton differentially localizes the early growth response gene-1 protein in cancer and benign cells of the prostate.
    Molecular cancer research : MCR, 2004, Volume: 2, Issue:2

    Topics: Active Transport, Cell Nucleus; Adenocarcinoma; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Nucleus; Cytoskeleton; DNA-Binding Proteins; Early Growth Response Protein 1; Humans; Immediate-Early Proteins; Immunohistochemistry; Male; Microtubules; Nocodazole; Paclitaxel; Prostate; Prostatic Neoplasms; Transcription Factors

2004
Intra-oocyte localization of MAD2 and its relationship with kinetochores, microtubules, and chromosomes in rat oocytes during meiosis.
    Biology of reproduction, 2004, Volume: 71, Issue:3

    Topics: Animals; Antibodies; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Calcium-Binding Proteins; Cell Cycle Proteins; Cells, Cultured; Chromosomes, Mammalian; Female; Kinetochores; Mad2 Proteins; Meiosis; Microtubules; Nocodazole; Oocytes; Paclitaxel; Polymers; Rats; Rats, Sprague-Dawley; Repressor Proteins; Spindle Apparatus; Tubulin

2004
Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt.
    Oncogene, 2004, Jul-29, Volume: 23, Issue:34

    Topics: Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; G2 Phase; Microtubules; Mitosis; Mutation; Nocodazole; Paclitaxel; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2004
Inactivation of the mitotic checkpoint as a determinant of the efficacy of microtubule-targeted drugs in killing human cancer cells.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Death; Cell Survival; Drug Resistance, Neoplasm; Female; Humans; Interphase; Microtubules; Mitosis; Nocodazole; Organ Specificity; Ovarian Neoplasms; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; Tumor Cells, Cultured

2004
Localization of microtubules during macronuclear division in Tetrahymena and possible involvement of macronuclear microtubules in 'amitotic' chromatin distribution.
    Cell structure and function, 1999, Volume: 24, Issue:5

    Topics: Animals; Benomyl; Cell Division; Cell Nucleus; Chromatin; Colchicine; Cytoplasm; DNA, Protozoan; Interphase; Micronucleus, Germline; Microtubules; Mitosis; Models, Biological; Nocodazole; Paclitaxel; Tetrahymena

1999
Cytoskeletal influences on nuclear shape in granulocytic HL-60 cells.
    BMC cell biology, 2004, Aug-19, Volume: 5

    Topics: Cell Differentiation; Cell Nucleus; Cell Shape; Cytochalasin D; Cytoskeleton; Hematopoiesis; HL-60 Cells; Humans; Lamin B Receptor; Lamin Type A; Lamin Type B; Microscopy, Confocal; Microscopy, Fluorescence; Nocodazole; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Receptors, Cytoplasmic and Nuclear; Tretinoin

2004
Localization of mitotic arrest deficient 1 (MAD1) in mouse oocytes during the first meiosis and its functions as a spindle checkpoint protein.
    Biology of reproduction, 2005, Volume: 72, Issue:1

    Topics: Animals; Antibodies; Cell Cycle Proteins; Cell Nucleus; Cells, Cultured; Chromosomes, Mammalian; Female; Kinetochores; Meiosis; Mice; Mice, Inbred Strains; Microinjections; Microtubules; Nocodazole; Nuclear Proteins; Oocytes; Paclitaxel; Spindle Apparatus

2005
Unloaded shortening velocity in single permeabilized vascular smooth muscle cells is independent of microtubule status.
    Journal of muscle research and cell motility, 2004, Volume: 25, Issue:2

    Topics: Actins; Animals; Calcium; Cell Adhesion; Cell Membrane Permeability; Cell Shape; Colchicine; Immunohistochemistry; Kinetics; Microscopy, Fluorescence; Microtubules; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nocodazole; Paclitaxel; Rabbits

2004
[Ca2+]i signaling between mitochondria and endoplasmic reticulum in neurons is regulated by microtubules. From mitochondrial permeability transition pore to Ca2+-induced Ca2+ release.
    The Journal of biological chemistry, 2005, Jan-07, Volume: 280, Issue:1

    Topics: Animals; Calcium Signaling; Cells, Cultured; Endoplasmic Reticulum; Ion Channels; Mice; Microtubules; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurons; Nocodazole; Paclitaxel

2005
Changes in physicochemical properties of microtubules lead to the formation of a single spherical structure of mitochondrial assembly enveloping nuclear chromatins.
    Journal of electron microscopy, 2004, Volume: 53, Issue:6

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Nucleus; Chromatin; Colchicine; Flow Cytometry; Humans; Immunohistochemistry; Microscopy, Confocal; Microscopy, Electron, Transmission; Microtubules; Mitochondria; Nocodazole; Paclitaxel

2004
Regulation of acetylated tubulin/Na+,K+-ATPase interaction by L-glutamate in non-neural cells: involvement of microtubules.
    Biochimica et biophysica acta, 2005, Jan-18, Volume: 1721, Issue:1-3

    Topics: Acetylation; Amino Acid Transport System X-AG; Animals; Cell Line; Glutamic Acid; Humans; Microtubules; Nocodazole; Paclitaxel; Sodium; Sodium-Potassium-Exchanging ATPase; Tubulin

2005
Concentric zones of active RhoA and Cdc42 around single cell wounds.
    The Journal of cell biology, 2005, Jan-31, Volume: 168, Issue:3

    Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cardiac Myosins; cdc42 GTP-Binding Protein; Cytochalasin D; Cytoskeleton; Female; Intracellular Signaling Peptides and Proteins; Kinetics; Lasers; Luminescent Proteins; Microinjections; Microscopy, Fluorescence; Microtubules; Models, Biological; Myosin Light Chains; Nerve Tissue Proteins; Nocodazole; Oocytes; Paclitaxel; Phosphorylation; rhoA GTP-Binding Protein; RNA, Messenger; Thiazoles; Thiazolidines; Toxins, Biological; Wiskott-Aldrich Syndrome Protein, Neuronal; Xenopus

2005
N-formyl-Met-Leu-Phe-induced oxidative burst in DMSO-differentiated HL-60 cells requires active Hsp90, but not intact microtubules.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2004, Volume: 148, Issue:2

    Topics: Cell Differentiation; Colchicine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; Microtubules; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nocodazole; Paclitaxel; Respiratory Burst

2004
Multi-lobulation of the nucleus in prolonged S phase by nuclear expression of Chk tyrosine kinase.
    Experimental cell research, 2005, Apr-01, Volume: 304, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cell Shape; Centrosome; Chlorocebus aethiops; COS Cells; Cyclin B; HeLa Cells; Humans; Lamin Type B; Microtubules; Mutation; Nocodazole; Nuclear Envelope; Nuclear Proteins; Paclitaxel; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); S Phase

2005
Mitotic spindle checkpoint inactivation by trichostatin a defines a mechanism for increasing cancer cell killing by microtubule-disrupting agents.
    Cancer biology & therapy, 2005, Volume: 4, Issue:2

    Topics: Antineoplastic Agents; Cell Cycle; Cell Cycle Proteins; Cell Survival; Centrosome; Drug Therapy, Combination; Enzyme Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; HeLa Cells; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunoblotting; Kinetochores; Microtubules; Mitosis; Neoplasms; Nocodazole; Paclitaxel; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Spindle Apparatus

2005
Paclitaxel impairs endothelial cell adhesion but not cytokine-induced cellular adhesion molecule expression.
    Annals of vascular surgery, 2005, Volume: 19, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Movement; Endothelial Cells; Humans; Myosin-Light-Chain Kinase; Nocodazole; Paclitaxel; Phosphorylation; Protein Kinase C; Protein Kinases

2005
Cdc2-mediated inhibition of epidermal growth factor activation of the extracellular signal-regulated kinase pathway during mitosis.
    The Journal of biological chemistry, 2005, Jul-01, Volume: 280, Issue:26

    Topics: CDC2 Protein Kinase; Cell Line, Tumor; Densitometry; Enzyme Activation; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Guanine Nucleotide Exchange Factors; HeLa Cells; Humans; Immunoblotting; Immunoprecipitation; Mitosis; Models, Biological; Nocodazole; Paclitaxel; Phosphorylation; Protein Binding; Protein Biosynthesis; Proto-Oncogene Proteins c-raf; Purines; Roscovitine; Signal Transduction; SOS1 Protein; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Vinblastine

2005
Selective and irreversible cell cycle inhibition by diphenyleneiodonium.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:6

    Topics: Biomarkers; Cell Cycle; Cell Line, Tumor; Cell Shape; Centrosome; Chromatin; Humans; Metaphase; Mitosis; Nocodazole; Onium Compounds; Paclitaxel; Spindle Apparatus

2005
Selective vulnerability of dopaminergic neurons to microtubule depolymerization.
    The Journal of biological chemistry, 2005, Oct-07, Volume: 280, Issue:40

    Topics: Cell Death; Colchicine; Cytosol; Dopamine; Humans; Microtubules; Nerve Degeneration; Nocodazole; Oxidative Stress; Paclitaxel; Parkinson Disease; Polymers; Receptors, Dopamine; Rotenone; Substantia Nigra; Uncoupling Agents

2005
Nocodazole, a microtubule de-polymerising agent, induces apoptosis of chronic lymphocytic leukaemia cells associated with changes in Bcl-2 phosphorylation and expression.
    Leukemia research, 2006, Volume: 30, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Caspase Inhibitors; Cysteine Proteinase Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Microtubules; Nocodazole; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

2006
Caspase-mediated specific cleavage of BubR1 is a determinant of mitotic progression.
    Molecular and cellular biology, 2005, Volume: 25, Issue:21

    Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Caspase 3; Caspase Inhibitors; Caspases; Cell Cycle; Cell Cycle Proteins; Chickens; Conserved Sequence; Doxycycline; Enzyme Activation; HeLa Cells; Humans; Mice; Microtubules; Molecular Sequence Data; Mutagenesis, Site-Directed; Nocodazole; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; Sequence Homology, Amino Acid; Spindle Apparatus; Xenopus laevis

2005
Comparison of the relative sensitivity of human lymphocytes and mouse splenocytes to two spindle poisons.
    Mutation research, 2005, Dec-30, Volume: 588, Issue:2

    Topics: Aneugens; Animals; Cell Proliferation; Concanavalin A; Cytochalasin B; Humans; Lymphocytes; Mice; Mitogens; Mutagenicity Tests; Nocodazole; Paclitaxel; Phytohemagglutinins; Spindle Apparatus; Spleen

2005
Cross-talk between DNA damage and cell survival checkpoints during G2 and mitosis: pharmacologic implications.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Caffeine; Cell Line; Cell Survival; DNA Damage; DNA Fragmentation; G2 Phase; Humans; Melphalan; Mitosis; Nocodazole; Paclitaxel; Signal Transduction

2005
Molecular dissection of internalization of Porphyromonas gingivalis by cells using fluorescent beads coated with bacterial membrane vesicle.
    Cell structure and function, 2005, Volume: 30, Issue:2

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Androstadienes; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Binding Proteins; Caveolin 1; Cell Membrane; Chromones; Clathrin; Cytochalasin D; Dynamin II; Endocytosis; Filipin; Fluorescent Dyes; G(M1) Ganglioside; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Membrane Lipids; Membrane Microdomains; Microtubules; Morpholines; Nocodazole; Nystatin; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Porphyromonas gingivalis; Recombinant Fusion Proteins; Sequence Deletion; Thiazoles; Thiazolidines; Tubulin; Wortmannin

2005
Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; ATPases Associated with Diverse Cellular Activities; Cysteine Proteinase Inhibitors; HeLa Cells; Humans; Leupeptins; LIM Domain Proteins; Mitosis; Nocodazole; Paclitaxel; Peptide Fragments; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Spindle Apparatus; Transcription Factors

2006
Dendrites contain a spacing pattern.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jan-25, Volume: 26, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cells, Cultured; Cerebellum; Dendrites; Diffusion; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Mice; Microtubule-Associated Proteins; Microtubules; Morphogenesis; Neocortex; Neurons; Nocodazole; Paclitaxel; Potassium Chloride; Pyramidal Cells; Rats; Sodium Channel Blockers; Staining and Labeling; Tetrodotoxin; Valine

2006
Asymmetrization of first cleavage by transient disassembly of one spindle pole aster in the leech Helobdella robusta.
    Developmental biology, 2006, Apr-01, Volume: 292, Issue:1

    Topics: Animals; Cleavage Stage, Ovum; Leeches; Microtubules; Nocodazole; Paclitaxel; Spindle Apparatus

2006
beta-Amyloid and endoplasmic reticulum stress responses in primary neurons: effects of drugs that interact with the cytoskeleton.
    Journal of molecular neuroscience : MN, 2006, Volume: 28, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antineoplastic Agents; Cells, Cultured; Cytoskeleton; Endoplasmic Reticulum; Epothilones; Eukaryotic Initiation Factor-2; HSP70 Heat-Shock Proteins; Membrane Proteins; Microtubules; Molecular Chaperones; Neurons; Nocodazole; Oxidative Stress; Paclitaxel; Peptide Fragments; Phosphorylation; Rats; Thapsigargin; Tubulin Modulators

2006
SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress.
    Oncogene, 2007, Feb-15, Volume: 26, Issue:7

    Topics: Cell Line, Tumor; Chromosomal Instability; Chromosomes, Human; Glioma; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Mitosis; Nocodazole; Paclitaxel; Polyploidy; Sirtuin 2; Sirtuins; Stress, Physiological; Tubulin; Ultraviolet Rays; X-Rays

2007
Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint.
    Molecular cell, 2006, Volume: 23, Issue:4

    Topics: Androgen-Binding Protein; Animals; Aurora Kinase B; Aurora Kinases; Centrosome; Chromatin; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; Humans; Kinetochores; MAP Kinase Kinase Kinases; Metaphase; Nocodazole; Paclitaxel; Phosphatidylethanolamine Binding Protein; Phosphorylation; Prostatein; Protein Serine-Threonine Kinases; Protein Transport; raf Kinases; Rats; Secretoglobins; Spindle Apparatus; Tumor Cells, Cultured; Uteroglobin

2006
Microtubule stability and MAP1B upregulation control neuritogenesis in CAD cells.
    Acta pharmacologica Sinica, 2006, Volume: 27, Issue:9

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Catecholamines; Cell Differentiation; Cell Line; Mice; Microtubule-Associated Proteins; Microtubules; Neurites; Neurons; Nocodazole; Paclitaxel; Tubulin; Up-Regulation

2006
The dynamic instability of microtubules is required for aggresome formation in oligodendroglial cells after proteolytic stress.
    Journal of molecular neuroscience : MN, 2006, Volume: 29, Issue:2

    Topics: Alternative Splicing; Cell Line; Crystallins; Cysteine Proteinase Inhibitors; Heat-Shock Proteins; Humans; Inclusion Bodies; Leupeptins; Microtubule-Organizing Center; Microtubules; Mitochondria; Nocodazole; Oligodendroglia; Oxidative Stress; Paclitaxel; Protein Isoforms; tau Proteins; Tubulin Modulators; Ubiquitin

2006
Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells.
    Journal of virology, 2007, Volume: 81, Issue:1

    Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Epstein-Barr Virus Nuclear Antigens; Gamma Rays; Herpesvirus 4, Human; Humans; Membrane Proteins; Mitosis; Nocodazole; Paclitaxel; Phenotype; Polyploidy; Proto-Oncogene Proteins; Spindle Apparatus; Tubulin Modulators; Viral Proteins; Virus Latency

2007
Disassembly of actin filaments by botulinum C2 toxin and actin-filament-disrupting agents induces assembly of microtubules in human leukaemia cell lines.
    Biology of the cell, 2007, Volume: 99, Issue:3

    Topics: Actin Cytoskeleton; Actins; Antineoplastic Agents; Botulinum Toxins; Cell Line, Tumor; Cell Polarity; HL-60 Cells; Humans; Leukemia; Microtubules; Nocodazole; Paclitaxel; Tubulin Modulators

2007
A comparative study of the cytoskeleton binding drugs nocodazole and taxol with a mammalian cell quartz crystal microbalance biosensor: different dynamic responses and energy dissipation effects.
    Analytical biochemistry, 2007, Feb-01, Volume: 361, Issue:1

    Topics: Animals; Aorta; Biosensing Techniques; Breast Neoplasms; Cattle; Cell Culture Techniques; Cell Line; Cell Line, Tumor; Cytoskeleton; Endothelium, Vascular; Female; Humans; Kinetics; Microscopy, Fluorescence; Nocodazole; Paclitaxel; Quartz; Tubulin

2007
Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis.
    The Journal of cell biology, 2007, Jan-15, Volume: 176, Issue:2

    Topics: Adenomatous Polyposis Coli Protein; Animals; Apoptosis; beta Catenin; Caspase 3; Cell Cycle Proteins; Cell Line, Tumor; Chromatin; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Fibroblasts; HCT116 Cells; Histones; Humans; Intestinal Mucosa; Intestines; Mice; Mice, Transgenic; Mitosis; Models, Biological; Nocodazole; Paclitaxel; Polyploidy; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Spindle Apparatus; Staurosporine

2007
MEK1/2 regulates microtubule organization, spindle pole tethering and asymmetric division during mouse oocyte meiotic maturation.
    Cell cycle (Georgetown, Tex.), 2007, Feb-01, Volume: 6, Issue:3

    Topics: Animals; Butadienes; Female; Fluorescent Antibody Technique; Immunoblotting; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Meiosis; Mice; Mice, Inbred ICR; Microscopy, Confocal; Microtubules; Nitriles; Nocodazole; Oocytes; Oogenesis; Paclitaxel; Phosphorylation; RNA Interference; Spindle Apparatus

2007
Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.
    Cancer cell, 2007, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinogens; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Segregation; Dimethylnitrosamine; Fibroblasts; Mice; Mice, Knockout; Mitosis; Molecular Sequence Data; Nocodazole; Paclitaxel; Stomach Neoplasms; Tumor Suppressor Proteins

2007
Microtubule-targeting-dependent reorganization of filopodia.
    Journal of cell science, 2007, Apr-01, Volume: 120, Issue:Pt 7

    Topics: Animals; Antibodies, Monoclonal; Cell Adhesion; Cells, Cultured; Fluorescent Antibody Technique, Direct; Fluorescent Dyes; Focal Adhesions; Immunohistochemistry; Kinetics; Luminescent Proteins; Melanoma, Experimental; Mice; Microscopy, Fluorescence; Microtubules; Nocodazole; Paclitaxel; Phalloidine; Pseudopodia; RNA Interference; Transfection; Tubulin; Tubulin Modulators

2007
Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells.
    Neurochemical research, 2007, Volume: 32, Issue:8

    Topics: Adult; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Child; Glioblastoma; Humans; Multiprotein Complexes; Nocodazole; Paclitaxel; Tubulin; Tubulin Modulators; Vinblastine

2007
A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.
    Nature cell biology, 2007, Volume: 9, Issue:5

    Topics: Antimitotic Agents; Calcium-Binding Proteins; Cell Cycle Proteins; Chromosome Segregation; Gene Library; Genomic Instability; Genomics; HeLa Cells; Humans; Kinetochores; Mad2 Proteins; MAP Kinase Kinase Kinases; Mitosis; Mutation; Nocodazole; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; Repressor Proteins; Reproducibility of Results; RNA Interference; Signal Transduction; Spindle Apparatus; Time Factors; Transfection; Tubulin Modulators

2007
BubR1 deficiency results in enhanced activation of MEK and ERKs upon microtubule stresses.
    Cell proliferation, 2007, Volume: 40, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Cycle Proteins; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; HeLa Cells; Humans; MAP Kinase Signaling System; Metaphase; Mice; Mice, Mutant Strains; Microtubules; Mitogen-Activated Protein Kinases; Nocodazole; Paclitaxel; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Spindle Apparatus; Tubulin Modulators

2007
Effect of inhibition of dynein function and microtubule-altering drugs on AAV2 transduction.
    Virology, 2007, Oct-10, Volume: 367, Issue:1

    Topics: Antineoplastic Agents; Dependovirus; Dyneins; HeLa Cells; Humans; Microtubules; Nocodazole; Paclitaxel; Recombination, Genetic; Transduction, Genetic; Tubulin Modulators; Vinblastine

2007
BUB1 mediation of caspase-independent mitotic death determines cell fate.
    The Journal of cell biology, 2007, Jul-16, Volume: 178, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis Inducing Factor; Benzoquinones; Caco-2 Cells; Caspases; Cell Line, Tumor; Chromosomes; Cold Temperature; DNA Fragmentation; DNA-Binding Proteins; Endodeoxyribonucleases; Enzyme Activation; Genomic Instability; HCT116 Cells; HeLa Cells; Humans; Lactams, Macrocyclic; Mitosis; Models, Biological; Nocodazole; Nuclear Proteins; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Tumor Protein p73; Tumor Suppressor Proteins

2007
Cytoskeleton and motor proteins are required for the transcytosis of Neisseria gonorrhoeae through polarized epithelial cells.
    International journal of medical microbiology : IJMM, 2008, Volume: 298, Issue:3-4

    Topics: Actins; Bacterial Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cytoskeletal Proteins; Dyneins; Epithelial Cells; Gonorrhea; Humans; Kinesins; Microtubules; Molecular Motor Proteins; Myosins; Neisseria gonorrhoeae; Nocodazole; Paclitaxel; Tumor Cells, Cultured; Vinblastine

2008
Disorganized microtubules underlie the formation of retraction bulbs and the failure of axonal regeneration.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Aug-22, Volume: 27, Issue:34

    Topics: Animals; Axons; Cells, Cultured; Central Nervous System; Cerebellum; Ganglia, Spinal; Green Fluorescent Proteins; Growth Cones; Luminescent Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Microtubules; Nerve Degeneration; Neurons; Nocodazole; Paclitaxel; Regeneration; Sciatic Neuropathy; Tubulin Modulators

2007
Kinesin-13 regulates flagellar, interphase, and mitotic microtubule dynamics in Giardia intestinalis.
    Eukaryotic cell, 2007, Volume: 6, Issue:12

    Topics: Animals; Flagella; Gene Expression Regulation; Giardia lamblia; Green Fluorescent Proteins; Interphase; Kinesins; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Mitosis; Models, Biological; Nocodazole; Paclitaxel; Tubulin Modulators

2007
Attenuation of actinomyosinII contractile activity in growth cones accelerates filopodia-guided and microtubule-based neurite elongation.
    Brain research, 2007, Oct-24, Volume: 1176

    Topics: Actomyosin; Amides; Animals; Central Nervous System; Chick Embryo; Contractile Proteins; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibronectins; Growth Cones; Heterocyclic Compounds, 4 or More Rings; Laminin; Microtubules; Neural Pathways; Neurites; Neurogenesis; Nocodazole; Paclitaxel; Pseudopodia; Pyridines; rho GTP-Binding Proteins; Tubulin Modulators

2007
Local stabilization of microtubule assembly improves recovery of facial nerve function after repair.
    Experimental neurology, 2008, Volume: 209, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Axons; Cell Count; Cheek; Data Interpretation, Statistical; Facial Muscles; Facial Nerve; Female; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Microtubules; Motor Endplate; Movement; Neurosurgical Procedures; Nocodazole; Paclitaxel; Rats; Rats, Wistar; Tissue Fixation; Tubulin; Vibrissae; Vinblastine

2008
Cell-cycle progression without an intact microtuble cytoskeleton.
    Current biology : CB, 2007, Dec-04, Volume: 17, Issue:23

    Topics: Anaphase; Cell Cycle; Cell Line; Cytoskeleton; Fibroblasts; Humans; Image Processing, Computer-Assisted; Microscopy, Video; Microtubules; Mitosis; Nocodazole; Paclitaxel; Telophase

2007
Fc receptor-mediated, antibody-dependent enhancement of bacteriophage lambda-mediated gene transfer in mammalian cells.
    Virology, 2008, Apr-10, Volume: 373, Issue:2

    Topics: Actins; Animals; Antibodies, Viral; Bacteriophage lambda; Bridged Bicyclo Compounds, Heterocyclic; Capsid Proteins; Cell Line; Chlorocebus aethiops; Chlorpromazine; COS Cells; Endocytosis; Gene Transfer Techniques; Glycoproteins; Humans; Luciferases; Mice; Microtubules; Models, Biological; Nocodazole; Paclitaxel; Receptors, IgG; Recombinant Proteins; Thiazolidines; Transduction, Genetic; Transfection

2008
Microtubule stabilization specifies initial neuronal polarization.
    The Journal of cell biology, 2008, Feb-11, Volume: 180, Issue:3

    Topics: Animals; Cell Differentiation; Cell Polarity; Cells, Cultured; Central Nervous System; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Growth Cones; Hippocampus; Intercellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Microtubules; Neurites; Neurons; Nocodazole; Paclitaxel; Protein Serine-Threonine Kinases; Rats; Tubulin Modulators

2008
Cytoskeleton inhibitors combined with TRAIL induce apoptosis in HeLa carcinoma cells overexpressing antiapoptotic protein Bcl-2.
    Biochemistry. Biokhimiia, 2008, Volume: 73, Issue:3

    Topics: Actin Cytoskeleton; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cytochalasin D; Cytochromes c; Demecolcine; HeLa Cells; Humans; Microtubules; Mitochondria; Nocodazole; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; TNF-Related Apoptosis-Inducing Ligand; Tubulin Modulators

2008
Different phosphorylation states of the anaphase promoting complex in response to antimitotic drugs: a quantitative proteomic analysis.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Apr-22, Volume: 105, Issue:16

    Topics: Anaphase-Promoting Complex-Cyclosome; Antimitotic Agents; HeLa Cells; Humans; Mass Spectrometry; Nocodazole; Paclitaxel; Phosphorylation; Prometaphase; Protein Subunits; Proteomics; Pyrimidines; Spindle Apparatus; Thiones; Ubiquitin-Protein Ligase Complexes; Vincristine

2008
Arsenite-induced mitotic death involves stress response and is independent of tubulin polymerization.
    Toxicology and applied pharmacology, 2008, Jul-15, Volume: 230, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Arsenites; Blotting, Western; Cell Death; Cell Nucleus; Cell Survival; Centrosome; Fever; Fluorescent Antibody Technique; Heat-Shock Proteins; HeLa Cells; Hot Temperature; Humans; Microtubules; Mitosis; Nocodazole; Paclitaxel; Spindle Apparatus; Stress, Physiological; Tubulin

2008
Mitotic arrest-associated apoptosis induced by sodium arsenite in A375 melanoma cells is BUBR1-dependent.
    Toxicology and applied pharmacology, 2008, Aug-15, Volume: 231, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Arsenites; Blotting, Western; CDC2 Protein Kinase; Fluorescent Antibody Technique; Humans; Melanoma, Experimental; Mitosis; Nocodazole; Paclitaxel; Protein Serine-Threonine Kinases; Purines; RNA, Small Interfering; Roscovitine; Sodium Compounds

2008
RhoA and microtubule dynamics control cell-basement membrane interaction in EMT during gastrulation.
    Nature cell biology, 2008, Volume: 10, Issue:7

    Topics: Animals; Basement Membrane; Biomarkers; Cell Membrane; Chick Embryo; Epithelium; Gastrulation; Humans; Laminin; Mesoderm; Microtubules; Nocodazole; Oncogene Proteins; Paclitaxel; rhoA GTP-Binding Protein; Tubulin Modulators

2008
BRCA1 is required for meiotic spindle assembly and spindle assembly checkpoint activation in mouse oocytes.
    Biology of reproduction, 2008, Volume: 79, Issue:4

    Topics: Aneuploidy; Animals; BRCA1 Protein; Cell Cycle Proteins; Cells, Cultured; Embryo, Mammalian; Female; Mad2 Proteins; Meiosis; Mice; Nocodazole; Nuclear Proteins; Oocytes; Oogenesis; Paclitaxel; Spindle Apparatus; Tissue Distribution; Tubulin Modulators

2008
Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied.
    The Journal of cell biology, 2008, Aug-25, Volume: 182, Issue:4

    Topics: Chromosome Segregation; HeLa Cells; Humans; Microtubules; Mitosis; Nocodazole; Paclitaxel; Spindle Apparatus; Temperature; Vinblastine

2008
The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS, HeLa) cells.
    Cell motility and the cytoskeleton, 2009, Volume: 66, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Line, Tumor; Cell Survival; Fluorescent Antibody Technique; HeLa Cells; Humans; Kinetochores; Microscopy; Microtubules; Mitosis; Nocodazole; Paclitaxel; Spindle Apparatus; Tubulin Modulators

2009
BRCA1 is regulated by Chk2 in response to spindle damage.
    Biochimica et biophysica acta, 2008, Volume: 1783, Issue:12

    Topics: Blotting, Western; BRCA1 Protein; Cell Survival; Centrosome; Checkpoint Kinase 2; DNA Damage; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoprecipitation; Microtubules; Mitosis; Mitotic Index; Mutation; Nocodazole; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; RNA, Small Interfering; Serine; Spindle Apparatus; Tubulin Modulators; Tumor Cells, Cultured

2008
The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes.
    The Journal of cell biology, 2008, Oct-06, Volume: 183, Issue:1

    Topics: Anaphase; Autoantigens; Calcium-Binding Proteins; Cell Cycle Proteins; Centromere Protein A; Chromatin; Chromosomal Proteins, Non-Histone; DNA Replication; Enzyme Inhibitors; Genome, Human; HeLa Cells; Humans; Hydroxyurea; Indoles; Kinetics; Kinetochores; Mad2 Proteins; Metaphase; Microscopy, Electron; Microtubules; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Pyrimidines; Repressor Proteins; Spindle Apparatus; Sulfonamides; Thiones

2008
GM1 induces p38 and microtubule dependent ramification of rat primary microglia in vitro.
    Brain research, 2008, Dec-09, Volume: 1244

    Topics: Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; G(M1) Ganglioside; Gangliosides; Imidazoles; Interferon-gamma; Lipopolysaccharides; Microglia; Microscopy, Confocal; Microtubules; Nerve Growth Factor; Neurotrophin 3; Nocodazole; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tubulin Modulators

2008
Microtubules in dendritic spine development.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Nov-12, Volume: 28, Issue:46

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dendritic Spines; Down-Regulation; Hippocampus; Microtubule-Associated Proteins; Microtubules; Neurogenesis; Neuronal Plasticity; Nocodazole; Paclitaxel; Rats; RNA Interference; Synapses; Tubulin Modulators

2008
An experimental and computational study of effects of microtubule stabilization on T-cell polarity.
    PloS one, 2008, Volume: 3, Issue:12

    Topics: Algorithms; Cell Polarity; Centrosome; Humans; Jurkat Cells; Microtubules; Models, Biological; Nocodazole; Paclitaxel; T-Lymphocytes

2008
Mitochondrial remodeling in differentiating neuroblasts.
    Brain research, 2009, Feb-03, Volume: 1252

    Topics: Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Cycle; Cell Differentiation; Cell Line; Hippocampus; Membrane Potential, Mitochondrial; Mice; Microtubules; Mitochondria; Neurites; Neurons; Nocodazole; Oxidative Phosphorylation; Paclitaxel; Pyruvic Acid; Stem Cells; Tretinoin

2009
Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis.
    Cancer research, 2009, Jan-01, Volume: 69, Issue:1

    Topics: Alleles; Aneuploidy; Animals; Cell Cycle Proteins; Cell Transformation, Neoplastic; Chromosome Segregation; Female; Fibroblasts; Kinetochores; Male; Mice; Mice, Inbred C57BL; Mutation; Nocodazole; Paclitaxel; Protein Serine-Threonine Kinases; RNA, Messenger; Spindle Apparatus

2009
Microtubule-dependent and microtubule-independent steps in Crimean-Congo hemorrhagic fever virus replication cycle.
    Virology, 2009, Mar-15, Volume: 385, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Viral; Antigens, Viral; Cell Survival; Chlorocebus aethiops; Hemorrhagic Fever Virus, Crimean-Congo; Microtubules; Nocodazole; Paclitaxel; RNA, Viral; Tubulin Modulators; Vero Cells; Virus Internalization; Virus Replication

2009
The inhibition of Aurora A abrogates the mitotic delay induced by microtubule perturbing agents.
    Cell cycle (Georgetown, Tex.), 2009, Mar-15, Volume: 8, Issue:6

    Topics: Aurora Kinase B; Aurora Kinases; Benzazepines; Cell Line, Tumor; Genes, cdc; Humans; Microtubules; Mitosis; Nocodazole; Paclitaxel; Protein Serine-Threonine Kinases; RNA, Small Interfering; Spindle Apparatus; Tubulin Modulators

2009
Role of cytoskeletal components in stress-relaxation behavior of adherent vascular smooth muscle cells.
    Journal of biomechanical engineering, 2009, Volume: 131, Issue:4

    Topics: Actins; Animals; Aorta; Cell Adhesion; Cytochalasin D; Depsipeptides; Elasticity; Endothelium, Vascular; Linear Models; Male; Microtubules; Models, Biological; Muscle Relaxation; Myocytes, Smooth Muscle; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Stress, Mechanical; Tubulin Modulators; Viscosity

2009
Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.
    Cancer research, 2009, May-01, Volume: 69, Issue:9

    Topics: Apoptosis; Aurora Kinase B; Aurora Kinases; Carbazoles; Chromosome Aberrations; Colonic Neoplasms; Drug Synergism; Enzyme Inhibitors; HCT116 Cells; Humans; Mitosis; Nocodazole; Paclitaxel; Protein Serine-Threonine Kinases; Spindle Apparatus

2009
Visualization of aberrant perinuclear microtubule aster organization by microtubule-destabilizing agents.
    Bioscience, biotechnology, and biochemistry, 2009, Volume: 73, Issue:5

    Topics: Cell Line, Tumor; Cell Nucleus; Cell Nucleus Division; Cell Survival; Dose-Response Relationship, Drug; Humans; Microtubules; Nocodazole; Paclitaxel; Tubulin Modulators; Vinblastine

2009
PHR regulates growth cone pausing at intermediate targets through microtubule disassembly.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, May-20, Volume: 29, Issue:20

    Topics: Animals; Anthracenes; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Death-Associated Protein Kinases; Dose-Response Relationship, Drug; Electroporation; Enzyme Inhibitors; Gene Expression Regulation; Green Fluorescent Proteins; Growth Cones; Imidazoles; MAP Kinase Kinase 4; Membrane Proteins; Mice; Mice, Transgenic; Microtubules; Neurons; Nocodazole; Paclitaxel; Phosphorylation; Prosencephalon; Pyridines; Signal Transduction; Spinal Cord; Tubulin Modulators; Zebrafish; Zebrafish Proteins

2009
Microtubule-interacting drugs induce moderate and reversible damage to human bone marrow mesenchymal stem cells.
    Cell proliferation, 2009, Volume: 42, Issue:4

    Topics: Bone Marrow Cells; Cell Cycle; Cell Death; Cell Nucleus; Cell Proliferation; Cells, Cultured; Gene Expression; Humans; Mesenchymal Stem Cells; Microtubules; Nocodazole; Nuclear Envelope; Paclitaxel; Tubulin; Tubulin Modulators; Tumor Suppressor Protein p53

2009
Length of mitotic arrest induced by microtubule-stabilizing drugs determines cell death after mitotic exit.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:6

    Topics: Benzamides; Caspase 3; Cell Death; Cell Proliferation; Cell Survival; Cyclin B; Cyclin B1; Epothilones; Fluorescent Antibody Technique; G1 Phase; HeLa Cells; Humans; Mitosis; Nocodazole; Paclitaxel; Quinazolines; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Tubulin Modulators

2009
Stabilization of anaphase midzone microtubules is regulated by Rho during cytokinesis in human fibrosarcoma cells.
    Experimental cell research, 2009, Oct-01, Volume: 315, Issue:16

    Topics: Anaphase; Animals; Cell Line, Tumor; Cytokinesis; Enzyme Activation; Fibrosarcoma; Heterocyclic Compounds, 4 or More Rings; Humans; Microtubule-Associated Proteins; Microtubules; Nocodazole; Paclitaxel; Proto-Oncogene Proteins; rho GTP-Binding Proteins; RNA Interference; Spindle Apparatus; Tubulin Modulators

2009
Basal endothelial nitric oxide synthase (eNOS) phosphorylation on Ser(1177) occurs in a stable microtubule- and tubulin acetylation-dependent manner.
    Experimental cell research, 2009, Dec-10, Volume: 315, Issue:20

    Topics: Acetylation; Cell Membrane; Cells, Cultured; Cytosol; Detergents; Endothelial Cells; Golgi Apparatus; Histone Deacetylase Inhibitors; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Intracellular Membranes; Membrane Microdomains; Microtubules; Nitric Oxide Synthase Type III; Nocodazole; Paclitaxel; Phosphorylation; Phosphoserine; Protein Binding; Recombinant Fusion Proteins; trans-Golgi Network; Transfection; Tubulin; Umbilical Veins

2009
Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments.
    The Journal of cell biology, 2009, Sep-07, Volume: 186, Issue:5

    Topics: Animals; Aurora Kinase B; Aurora Kinases; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Line; Cyclin B; Dose-Response Relationship, Drug; Focal Adhesion Kinase 1; Hesperidin; Humans; Kinetochores; Mad2 Proteins; Microtubules; Mitosis; Nocodazole; Paclitaxel; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Repressor Proteins; Spindle Apparatus; Tubulin Modulators

2009
P115 RhoGEF and microtubules decide the direction apoptotic cells extrude from an epithelium.
    The Journal of cell biology, 2009, Sep-07, Volume: 186, Issue:5

    Topics: Actins; Animals; Apoptosis; Biomarkers; Cell Line; Cell Polarity; Dogs; Epithelial Cells; Epithelium; Guanine Nucleotide Exchange Factors; Humans; Microtubules; Myosin Type II; Nocodazole; Paclitaxel; Rho Guanine Nucleotide Exchange Factors; RNA, Small Interfering; Tubulin Modulators; Zebrafish

2009
Dynamics of ballistically injected latex particles in living human endothelial cells.
    Biorheology, 2009, Volume: 46, Issue:4

    Topics: Actins; Adenosine Triphosphate; Biolistics; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Depsipeptides; Endothelium, Vascular; Fluorescent Dyes; Humans; Latex; Microscopy, Fluorescence; Nocodazole; Paclitaxel; Thiazolidines

2009
An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor.
    PloS one, 2009, Oct-05, Volume: 4, Issue:10

    Topics: Genome, Human; Green Fluorescent Proteins; HeLa Cells; Humans; Image Processing, Computer-Assisted; Kinesins; Models, Biological; Models, Statistical; Neoplasms; Nocodazole; Paclitaxel; RNA, Small Interfering; Spindle Apparatus; Time Factors; Tubulin Modulators

2009
Astrin regulates meiotic spindle organization, spindle pole tethering and cell cycle progression in mouse oocytes.
    Cell cycle (Georgetown, Tex.), 2009, Oct-15, Volume: 8, Issue:20

    Topics: Animals; Aurora Kinase A; Aurora Kinases; Cell Cycle Proteins; Meiosis; Metaphase; Mice; Microtubules; Mutagenesis, Site-Directed; Nocodazole; Oocytes; Paclitaxel; Phosphorylation; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Tubulin Modulators

2009
The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex.
    Molecular biology of the cell, 2009, Volume: 20, Issue:24

    Topics: Anaphase; Aurora Kinase B; Aurora Kinases; Chromosome Segregation; Chromosomes, Human; Cytokinesis; HeLa Cells; Humans; Kinesins; Kinetochores; Mitosis; Nocodazole; Nuclear Pore Complex Proteins; Nuclear Proteins; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Pyrimidines; Spindle Apparatus; Substrate Specificity; Thiones

2009
Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells.
    The Journal of biological chemistry, 2010, Feb-05, Volume: 285, Issue:6

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; Drosophila Proteins; Drug Resistance, Neoplasm; Etoposide; Female; Fibroblasts; Heat-Shock Proteins; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondrial Proteins; Neoplasms, Experimental; Nocodazole; Paclitaxel; Transfection; Transplantation, Heterologous; Tumor Suppressor Protein p53

2010
Spontaneous migration of cancer cells under conditions of mechanical confinement.
    Integrative biology : quantitative biosciences from nano to macro, 2009, Volume: 1, Issue:8-9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Humans; Microfluidics; Microscopy, Phase-Contrast; Microtubules; Neoplasms; Nocodazole; Paclitaxel

2009
Sequestration of free tubulin molecules by the viral protein NSP2 induces microtubule depolymerization during rotavirus infection.
    Journal of virology, 2010, Volume: 84, Issue:5

    Topics: Animals; Binding Sites; Cell Line; Microtubules; Models, Molecular; Mutagenesis, Site-Directed; Nocodazole; Paclitaxel; Protein Binding; Protein Conformation; RNA-Binding Proteins; Rotavirus; Rotavirus Infections; Tubulin; Tubulin Modulators; Viral Nonstructural Proteins

2010
The kinetics of force-induced cell reorganization depend on microtubules and actin.
    Cytoskeleton (Hoboken, N.J.), 2010, Volume: 67, Issue:4

    Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cell Polarity; Cells, Cultured; Cytochalasin D; Depsipeptides; Heterocyclic Compounds, 4 or More Rings; Kinetics; Mice; Microtubules; NIH 3T3 Cells; Nocodazole; Paclitaxel; Structure-Activity Relationship; Thiazolidines

2010
Septin2 is modified by SUMOylation and required for chromosome congression in mouse oocytes.
    Cell cycle (Georgetown, Tex.), 2010, Apr-15, Volume: 9, Issue:8

    Topics: Animals; Chromosome Segregation; Chromosomes; Cytokinesis; Female; Meiosis; Metaphase; Mice; Nocodazole; Oocytes; Paclitaxel; RNA Interference; RNA, Small Interfering; Septins; Spindle Apparatus; SUMO-1 Protein; Sumoylation

2010
MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment.
    PloS one, 2010, Jun-28, Volume: 5, Issue:6

    Topics: Animals; Kinetochores; MAP Kinase Kinase 2; Meiosis; Mice; Microtubules; Nocodazole; Nondisjunction, Genetic; Oocytes; Paclitaxel; Spindle Apparatus; Subcellular Fractions

2010
Computational analysis of the effects of antineoplastic agents on axonal transport.
    Journal of pharmacological sciences, 2010, Volume: 114, Issue:2

    Topics: Animals; Antineoplastic Agents; Axonal Transport; Carbocyanines; Cells, Cultured; Chick Embryo; Cisplatin; Computational Biology; Fluorescent Dyes; Fluorouracil; Ganglia, Spinal; Neurons; Nocodazole; Organelles; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Sodium Azide; Software; Vincristine

2010
Tubulin pools in human erythrocytes: altered distribution in hypertensive patients affects Na+, K+-ATPase activity.
    Cellular and molecular life sciences : CMLS, 2011, Volume: 68, Issue:10

    Topics: Acetylation; Adult; Aged; Antibodies, Monoclonal; Cell Membrane; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Nocodazole; Paclitaxel; Sodium-Potassium-Exchanging ATPase; Tubulin

2011
The flavonoid quercetin transiently inhibits the activity of taxol and nocodazole through interference with the cell cycle.
    Nutrition and cancer, 2010, Volume: 62, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin B1; Food-Drug Interactions; G2 Phase; Humans; Microtubules; Neoplasms; Nocodazole; Osmolar Concentration; Paclitaxel; Quercetin; Time Factors; Tubulin; Tubulin Modulators; Tumor Suppressor Protein p53

2010
Acetylated microtubules are required for fusion of autophagosomes with lysosomes.
    BMC cell biology, 2010, Nov-22, Volume: 11

    Topics: Acetylation; Adaptor Proteins, Signal Transducing; Autophagy; Green Fluorescent Proteins; HeLa Cells; Humans; Lysosomes; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Nocodazole; Paclitaxel; Phagosomes; Recombinant Fusion Proteins; Sequestosome-1 Protein; Vinblastine

2010
Nakiterpiosin targets tubulin and triggers mitotic catastrophe in human cancer cells.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:12

    Topics: Acetylation; Cell Line, Tumor; Cell Survival; Centrosome; Chromosomes, Human; Drug Resistance, Neoplasm; Golgi Apparatus; Homosteroids; Humans; Interphase; Microtubule-Associated Proteins; Microtubules; Mitosis; Nocodazole; Paclitaxel; Polymerization; Protein Transport; Spindle Apparatus; Tubulin

2010
Free tubulin modulates mitochondrial membrane potential in cancer cells.
    Cancer research, 2010, Dec-15, Volume: 70, Issue:24

    Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Membrane; Colchicine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic CMP; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Liver Neoplasms; Male; Membrane Potential, Mitochondrial; Membrane Potentials; Microtubules; Mitochondria, Liver; Neoplasms; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Rhodamines; Rotenone; Tubulin

2010
Microtubule disruption targets HIF-1alpha mRNA to cytoplasmic P-bodies for translational repression.
    The Journal of cell biology, 2011, Jan-10, Volume: 192, Issue:1

    Topics: 3' Untranslated Regions; Argonaute Proteins; Chemical Precipitation; Cytoplasmic Structures; Eukaryotic Initiation Factor-2; Green Fluorescent Proteins; HeLa Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Microtubules; Nocodazole; Paclitaxel; Polymerization; Protein Binding; Protein Biosynthesis; Recombinant Fusion Proteins; RNA Transport; RNA, Messenger; Tubulin

2011
Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture.
    Oncotarget, 2011, Volume: 2, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line, Tumor; Cytoprotection; Epithelial Cells; Fibroblasts; G1 Phase; Humans; Imidazoles; Metformin; Nocodazole; Paclitaxel; Piperazines; Sirolimus; Tumor Suppressor Protein p53

2011
The small GTPase Cdc42 promotes membrane protrusion during polar body emission via ARP2-nucleated actin polymerization.
    Molecular human reproduction, 2011, Volume: 17, Issue:5

    Topics: Actin-Related Protein 2; Actins; Animals; Asymmetric Cell Division; Cytokinesis; Female; Gene Expression Regulation, Developmental; Meiosis; Metaphase; Monomeric GTP-Binding Proteins; Nocodazole; Paclitaxel; Polar Bodies; Polymerization; rhoA GTP-Binding Protein; Tubulin Modulators; Xenopus laevis; Xenopus Proteins

2011
Cellular studies reveal mechanistic differences between taccalonolide A and paclitaxel.
    Cell cycle (Georgetown, Tex.), 2011, Jul-01, Volume: 10, Issue:13

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Proliferation; HeLa Cells; Humans; Interphase; Macrolides; Microtubules; Nocodazole; Paclitaxel; Steroids; Tubulin Modulators

2011
CDK1, not ERK1/2 or ERK5, is required for mitotic phosphorylation of BIMEL.
    Cellular signalling, 2012, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; CDC2 Protein Kinase; Cell Cycle Checkpoints; Enzyme Activation; Enzyme Assays; Genes, Reporter; HEK293 Cells; Humans; Leupeptins; Luciferases, Renilla; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 7; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteolysis; Proto-Oncogene Proteins; Recombinant Fusion Proteins

2012
Septin1 is required for spindle assembly and chromosome congression in mouse oocytes.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2011, Volume: 240, Issue:10

    Topics: Aneuploidy; Animals; Chromosome Segregation; Chromosomes; Female; Meiosis; Mice; Nocodazole; Oocytes; Paclitaxel; RNA, Small Interfering; Septins; Spindle Apparatus; Tubulin Modulators

2011
Microtubule dynamics regulate cyclic stretch-induced cell alignment in human airway smooth muscle cells.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Actins; Bronchi; Cell Movement; Humans; Microscopy, Fluorescence; Microtubules; Models, Biological; Myocytes, Smooth Muscle; Nocodazole; Paclitaxel; Stress, Mechanical

2011
The role of PSD-95 and cypin in morphological changes in dendrites following sublethal NMDA exposure.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Oct-26, Volume: 31, Issue:43

    Topics: Analysis of Variance; Animals; Carrier Proteins; Dendrites; Disks Large Homolog 4 Protein; Embryo, Mammalian; Excitatory Amino Acid Agonists; Gene Expression Regulation; Green Fluorescent Proteins; Guanine Deaminase; Hippocampus; Indoles; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microtubule-Associated Proteins; N-Methylaspartate; Neurons; Nocodazole; Paclitaxel; Rats; Ribosomal Proteins; RNA, Small Interfering; Time Factors; Transfection; Tubulin; Tubulin Modulators

2011
Cyclin B1 interacts with the BH3-only protein Bim and mediates its phosphorylation by Cdk1 during mitosis.
    Cell cycle (Georgetown, Tex.), 2011, Nov-15, Volume: 10, Issue:22

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Line; Cyclin B1; Humans; K562 Cells; Membrane Proteins; Microtubules; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Purines; Quinolines; RNA Interference; Thiazoles

2011
Synergistic antitumor effects of novel HDAC inhibitors and paclitaxel in vitro and in vivo.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: Acetylation; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cyclin-Dependent Kinase Inhibitor p21; Drug Synergism; Female; Histone Deacetylase Inhibitors; Humans; Mice; Microtubules; Mitochondria; Nocodazole; Paclitaxel; Polymerization; Tubulin; Tumor Suppressor Protein p53; Vinblastine; Vinorelbine; Xenograft Model Antitumor Assays

2011
Who needs microtubules? Myogenic reorganization of MTOC, Golgi complex and ER exit sites persists despite lack of normal microtubule tracks.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: Animals; Biological Transport; Cells, Cultured; Endoplasmic Reticulum; Enzyme Inhibitors; Golgi Apparatus; Mice; Microtubules; Muscle, Skeletal; Nocodazole; Paclitaxel

2011
Tau protein is involved in morphological plasticity in hippocampal neurons in response to BDNF.
    Neurochemistry international, 2012, Volume: 60, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dendritic Spines; Fluorescent Antibody Technique; Gene Silencing; Hippocampus; Immunohistochemistry; Neurites; Neuronal Plasticity; Neurons; Nocodazole; Paclitaxel; Phosphorylation; Plasmids; Rats; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; tau Proteins; Transfection

2012
Relationship between the structures of taxane derivatives and their microtubule polymerization activity.
    Bioscience, biotechnology, and biochemistry, 2012, Volume: 76, Issue:2

    Topics: Animals; Antineoplastic Agents; Bridged-Ring Compounds; Humans; Microtubules; Molecular Structure; Nocodazole; Paclitaxel; Polymerization; Structure-Activity Relationship; Taxoids; Tubulin

2012
The microtubule cytoskeleton is required for a G2 cell cycle delay in cancer cells lacking stathmin and p53.
    Cytoskeleton (Hoboken, N.J.), 2012, Volume: 69, Issue:5

    Topics: Apoptosis; Centrosome; Cytoskeleton; G2 Phase; HeLa Cells; Humans; Microtubules; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; RNA, Small Interfering; Stathmin; Tubulin; Tubulin Modulators; Tumor Suppressor Protein p53; Vinblastine

2012
A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint.
    Genes & development, 2012, Mar-15, Volume: 26, Issue:6

    Topics: Aurora Kinase B; Aurora Kinases; Cell Cycle Proteins; Chromosomal Proteins, Non-Histone; Cytoskeletal Proteins; DNA-Binding Proteins; HeLa Cells; Humans; Kinetochores; M Phase Cell Cycle Checkpoints; Nocodazole; Paclitaxel; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae Proteins; Spindle Apparatus; Tubulin Modulators

2012
Comparison of the aneugenic properties of nocodazole, paclitaxel and griseofulvin in vitro. Centrosome defects and alterations in protein expression profiles.
    Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:9

    Topics: Aneugens; Aneuploidy; Animals; Antifungal Agents; Antineoplastic Agents; Apoptosis; Cell Cycle; Centrosome; Fibroblasts; Fluorescent Antibody Technique; Griseofulvin; Humans; Interphase; MCF-7 Cells; Metaphase; Mice; Microtubules; Myoblasts; Nocodazole; Paclitaxel; Transcriptome; Tubulin

2013
Cytoskeletal architecture regulates cyclooxygenase-2 in human endothelial cells: autocrine modulation by prostacyclin.
    Journal of cellular physiology, 2012, Volume: 227, Issue:12

    Topics: Actins; Autocrine Communication; Cells, Cultured; Cyclooxygenase 2; Cytoskeleton; Endothelial Cells; Epoprostenol; Gene Expression Regulation; Glutathione; Humans; Nocodazole; Paclitaxel; Signal Transduction; Tubulin Modulators

2012
Involvement of membrane tubulin in erythrocyte deformability and blood pressure.
    Journal of hypertension, 2012, Volume: 30, Issue:7

    Topics: Adult; Animals; Blood Pressure; Cell Membrane; Erythrocyte Deformability; Humans; Hypertension; Male; Membrane Proteins; Microscopy, Fluorescence; Nocodazole; Paclitaxel; Rats; Rats, Inbred SHR; Rats, Wistar; Tubulin

2012
Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice.
    Disease models & mechanisms, 2013, Volume: 6, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Axonal Transport; Axons; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Hippocampus; Humans; Mice; Mice, Knockout; Microtubules; Models, Neurological; Mutation; Neurons; Nocodazole; Paclitaxel; Spastic Paraplegia, Hereditary; Spastin; Vinblastine

2013
Highly dynamic microtubules improve the effectiveness of early stages of human influenza A/NWS/33 virus infection in LLC-MK2 cells.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Acetylation; Animals; Cell Line; Cell Shape; Dogs; Gene Expression Regulation; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Macaca mulatta; Microtubule-Associated Proteins; Microtubules; Nocodazole; Organ Specificity; Paclitaxel; Protein Binding; Protein Processing, Post-Translational; RNA Interference; Swine; Tubulin; Tubulin Modulators; Virus Replication

2012
Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:9

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Amyloid beta-Protein Precursor; Animals; Axonal Transport; Biomarkers; Case-Control Studies; Chromogranin B; Female; Humans; Kinetics; Male; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Microtubules; Mutation, Missense; Neuregulin-1; Nocodazole; Noscapine; Paclitaxel; Parkinson Disease, Secondary; Superoxide Dismutase; Superoxide Dismutase-1; tau Proteins; Tubulin Modulators

2012
[Sensitivity to chemotherapeutic drugs of polyploid tumor cells induced by a spindle poison nocodazole].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2012, Volume: 34, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Docetaxel; Down-Regulation; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Female; Fluorouracil; Gene Knockdown Techniques; Humans; Inhibitory Concentration 50; Nocodazole; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Polyploidy; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; RNA, Small Interfering; Taxoids; Vincristine

2012
Elasticity maps of living neurons measured by combined fluorescence and atomic force microscopy.
    Biophysical journal, 2012, Sep-05, Volume: 103, Issue:5

    Topics: Animals; Cell Survival; Cerebral Cortex; Cytoskeleton; Elasticity; Embryonic Stem Cells; Ganglia, Spinal; Mice; Microscopy, Atomic Force; Microscopy, Fluorescence; Neurites; Neurons; Nocodazole; Paclitaxel; Rats; Surface Properties; Time Factors

2012
A confocal-based morphometric analysis shows a functional crosstalk between the actin filament system and microtubules in thrombin-stimulated platelets.
    Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:1

    Topics: Actin Cytoskeleton; Animals; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Mice; Microscopy, Confocal; Microtubules; Nocodazole; Paclitaxel; Signal Transduction; Thiazolidines; Thrombin

2013
Abnormal expression of the mitotic checkpoint protein BubR1 contributes to the anti-microtubule drug resistance of esophageal squamous cell carcinoma cells.
    Oncology reports, 2013, Volume: 29, Issue:1

    Topics: Apoptosis; Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Proliferation; Drug Resistance, Neoplasm; Esophageal Neoplasms; Esophagus; Female; Humans; Male; Middle Aged; Mitotic Index; Neoplasm Staging; Nocodazole; Paclitaxel; Prognosis; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tubulin Modulators; Tumor Cells, Cultured

2013
Nek9 regulates spindle organization and cell cycle progression during mouse oocyte meiosis and its location in early embryo mitosis.
    Cell cycle (Georgetown, Tex.), 2012, Dec-01, Volume: 11, Issue:23

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Cycle Proteins; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Chromosomes; Female; Kinetochores; M Phase Cell Cycle Checkpoints; Meiosis; Mice; Mice, Inbred ICR; Mitosis; Morpholinos; NIMA-Related Kinases; Nocodazole; Oocytes; Paclitaxel; Poly-ADP-Ribose Binding Proteins; Protein Serine-Threonine Kinases; Spindle Apparatus; Tubulin

2012
WHAMM is required for meiotic spindle migration and asymmetric cytokinesis in mouse oocytes.
    Histochemistry and cell biology, 2013, Volume: 139, Issue:4

    Topics: Animals; Biological Transport; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Cytokinesis; Cytoskeletal Proteins; Endoplasmic Reticulum; Female; Golgi Apparatus; Meiosis; Mice; Mice, Inbred ICR; Microtubules; Nocodazole; Oocytes; Paclitaxel; RNA Interference; RNA, Small Interfering; Spindle Apparatus; Tubulin Modulators

2013
Sequential Cdk1 and Plk1 phosphorylation of protein tyrosine phosphatase 1B promotes mitotic cell death.
    Cell death & disease, 2013, Jan-24, Volume: 4

    Topics: Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Cycle Proteins; Cyclin B1; Humans; Immunoprecipitation; K562 Cells; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins; Recombinant Proteins; Serine

2013
The MAD1 1673 G → A polymorphism alters the function of the mitotic spindle assembly checkpoint and is associated with a worse response to induction chemotherapy and sensitivity to treatment in patients with advanced epithelial ovarian cancer.
    Pharmacogenetics and genomics, 2013, Volume: 23, Issue:4

    Topics: Biomarkers, Pharmacological; Calcium-Binding Proteins; Carcinoma, Ovarian Epithelial; Cell Cycle Proteins; Chromosomal Instability; Female; Genetic Association Studies; Humans; M Phase Cell Cycle Checkpoints; Mad2 Proteins; Microtubules; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Nocodazole; Nuclear Proteins; Ovarian Neoplasms; Paclitaxel; Polymorphism, Single Nucleotide; Repressor Proteins

2013
BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:9

    Topics: Antimitotic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Biomarkers; Biphenyl Compounds; Breast Neoplasms; DNA Methylation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Heterocyclic Compounds, 2-Ring; Humans; MCF-7 Cells; Neoplasm Metastasis; Nitrophenols; Nocodazole; Paclitaxel; Piperazines; Prognosis; Pteridines; Sulfonamides

2013
Centrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage.
    The Journal of cell biology, 2013, Sep-02, Volume: 202, Issue:5

    Topics: Antigen-Presenting Cells; Calcium; Cell Membrane; Cell Polarity; Centrosome; Dyneins; Humans; Immunological Synapses; Jurkat Cells; Lymphocyte Function-Associated Antigen-1; Microtubule-Organizing Center; Microtubules; Nocodazole; Optical Tweezers; Paclitaxel; Polymerization; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes

2013
CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation.
    Cancer research, 2013, Nov-15, Volume: 73, Issue:22

    Topics: Antineoplastic Agents; Binding Sites; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; MCF-7 Cells; Mitosis; Nocodazole; Nuclear Proteins; Paclitaxel; Phosphorylation; Transcription Factors; Up-Regulation

2013
Microtubule disorganization affects the mitochondrial permeability transition pore in cardiac myocytes.
    Circulation journal : official journal of the Japanese Circulation Society, 2014, Volume: 78, Issue:5

    Topics: Animals; Cyclosporine; Enzyme Inhibitors; GTP Phosphohydrolases; Male; Membrane Potential, Mitochondrial; Membrane Proteins; Microtubules; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; Myocytes, Cardiac; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Ruthenium Compounds; Thapsigargin; Tubulin Modulators

2014
The cellular distribution and Ser262 phosphorylation of tau protein are regulated by BDNF in vitro.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Line, Tumor; Humans; Intracellular Space; Neurites; Nocodazole; Paclitaxel; Phosphorylation; Protein Transport; Pyramidal Cells; Rats; tau Proteins; Tretinoin

2014
Phospho-Bcl-xL(Ser62) influences spindle assembly and chromosome segregation during mitosis.
    Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:8

    Topics: bcl-X Protein; Cell Cycle Proteins; Chromosome Segregation; HeLa Cells; Humans; M Phase Cell Cycle Checkpoints; Microtubules; Mitogen-Activated Protein Kinase 14; Mitosis; Mutation; Nocodazole; Paclitaxel; Phosphorylation; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Serine; Signal Transduction; Tubulin Modulators

2014
Prion-like nanofibrils of small molecules (PriSM) selectively inhibit cancer cells by impeding cytoskeleton dynamics.
    The Journal of biological chemistry, 2014, Oct-17, Volume: 289, Issue:42

    Topics: Antineoplastic Agents; Apoptosis; Cytoskeleton; Endocytosis; Glioblastoma; HeLa Cells; Hep G2 Cells; Humans; MCF-7 Cells; Nanoparticles; Nanotechnology; Neoplasm Transplantation; Neoplasms; Nocodazole; Paclitaxel; Peptides; Prions; Protein Structure, Tertiary; tau Proteins; Tubulin

2014
Inhibition of microtubule dynamics affects podosome belt formation during osteoclast induction.
    Cell biochemistry and biophysics, 2015, Volume: 71, Issue:2

    Topics: Acid Phosphatase; Animals; Cell Count; Cell Differentiation; Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Isoenzymes; Mice; Microtubule-Associated Proteins; Microtubules; Nocodazole; Osteoclasts; Paclitaxel; RANK Ligand; Tartrate-Resistant Acid Phosphatase

2015
TGN38 is required for the metaphase I/anaphase I transition and asymmetric cell division during mouse oocyte meiotic maturation.
    Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:17

    Topics: Actins; Anaphase; Animals; Asymmetric Cell Division; Female; Gene Knockdown Techniques; Meiosis; Membrane Glycoproteins; Metaphase; Mice, Inbred ICR; Nocodazole; Oocytes; Paclitaxel; Polar Bodies; Protein Transport; RNA, Small Interfering; Spindle Apparatus; Subcellular Fractions

2014
Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
    Journal of molecular medicine (Berlin, Germany), 2015, Volume: 93, Issue:5

    Topics: Animals; Apoptosis; Burkitt Lymphoma; Caspase Inhibitors; Caspases; Cell Line; DNA Fragmentation; Flow Cytometry; Gene Knockout Techniques; Humans; Mice; Mice, Knockout; Mitosis; Nocodazole; Paclitaxel; Ploidies; Polyploidy; Proto-Oncogene Proteins c-bcl-2; Tubulin Modulators; Vincristine

2015
Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells – a critical role of Cdk1 in mitotic entry.
    Biochemical pharmacology, 2015, Mar-01, Volume: 94, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Line, Tumor; Cyclin B1; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Leupeptins; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitosis; Nocodazole; Paclitaxel; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Quinazolines; RNA, Small Interfering; Signal Transduction; Tubulin Modulators; Vincristine

2015
QnAs with Patrick Moore.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, May-12, Volume: 112, Issue:19

    Topics: Cell Division; Herpesvirus 8, Human; Humans; Merkel cell polyomavirus; Mitosis; Neoplasms; Nocodazole; Oncogene Proteins; Oncogenic Viruses; Paclitaxel

2015
Phosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis.
    Molecular and cellular biology, 2015, Volume: 35, Issue:15

    Topics: CDC2 Protein Kinase; Cell Cycle Proteins; Cell Line, Tumor; Cyclin B1; Cyclin-Dependent Kinases; DNA Damage; HeLa Cells; Heterogeneous-Nuclear Ribonucleoprotein U; Humans; Mitosis; Nocodazole; Paclitaxel; Phosphoprotein Phosphatases; Phosphorylation; Polo-Like Kinase 1; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA Interference; RNA, Small Interfering; Securin; Tubulin Modulators

2015
Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.
    Nature communications, 2015, Oct-01, Volume: 6

    Topics: Anaphase-Promoting Complex-Cyclosome; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line; Chromosome Segregation; Humans; Mitosis; Morpholines; Nocodazole; Paclitaxel; Protein Kinase Inhibitors; Purines; RNA, Small Interfering; Sister Chromatid Exchange; Tubulin Modulators

2015
Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition.
    Oncotarget, 2016, Jan-05, Volume: 7, Issue:1

    Topics: Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Diploidy; HCT116 Cells; Humans; Immunoblotting; M Phase Cell Cycle Checkpoints; Microscopy, Fluorescence; Mitosis; Morpholines; Neoplasms; Nocodazole; Paclitaxel; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Purines; RNA Interference; Tetraploidy; Time-Lapse Imaging; Tubulin Modulators

2016
Microtubule-associated protein 1b is required for shaping the neural tube.
    Neural development, 2016, Jan-18, Volume: 11

    Topics: Animals; Cell Movement; Cell Polarity; Microtubule-Associated Proteins; Neural Tube; Neurulation; Nocodazole; Paclitaxel; Tubulin Modulators; Zebrafish; Zebrafish Proteins

2016
Promotion of Functional Nerve Regeneration by Inhibition of Microtubule Detyrosination.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Apr-06, Volume: 36, Issue:14

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Axons; Dose-Response Relationship, Drug; Gene Knock-In Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Mice; Mice, Inbred C57BL; Microtubules; Nerve Regeneration; Nocodazole; Paclitaxel; Peripheral Nerves; Phosphorylation; Sciatic Nerve; Sesquiterpenes; Tyrosine

2016
Asymmetric Distribution of Primary Cilia Allocates Satellite Cells for Self-Renewal.
    Stem cell reports, 2016, 06-14, Volume: 6, Issue:6

    Topics: ADP-Ribosylation Factors; Animals; Cardiotoxins; Caveolin 1; Cell Cycle; Cell Proliferation; Cilia; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Myofibrils; Myogenin; Nocodazole; Paclitaxel; PAX7 Transcription Factor; Satellite Cells, Skeletal Muscle; Signal Transduction

2016
Inhibition of Bcl-xL sensitizes cells to mitotic blockers, but not mitotic drivers.
    Open biology, 2016, Volume: 6, Issue:8

    Topics: Apoptosis; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Humans; M Phase Cell Cycle Checkpoints; Mitosis; Myeloid Cell Leukemia Sequence 1 Protein; Nocodazole; Paclitaxel; Small Molecule Libraries; Tubulin Modulators

2016
The Motor KIF5C Links the Requirements of Stable Microtubules and IGF-1 Receptor Membrane Insertion for Neuronal Polarization.
    Molecular neurobiology, 2017, Volume: 54, Issue:8

    Topics: Animals; Cell Membrane; Cell Polarity; Cells, Cultured; Cytochalasin D; Hippocampus; Kinesins; Microtubules; Neurites; Neurons; Nocodazole; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Qa-SNARE Proteins; R-SNARE Proteins; Rats; Receptor, IGF Type 1; Tubulin Modulators

2017
Kif2a regulates spindle organization and cell cycle progression in meiotic oocytes.
    Scientific reports, 2016, 12-19, Volume: 6

    Topics: Animals; Cell Differentiation; Chromosome Segregation; Chromosomes, Mammalian; Female; Gene Knockdown Techniques; Kinesins; M Phase Cell Cycle Checkpoints; Meiosis; Mice, Inbred ICR; Nocodazole; Oocytes; Paclitaxel; Polar Bodies; Repressor Proteins; Spindle Apparatus; Subcellular Fractions; Tubulin

2016
Toward Discovery of Novel Microtubule Targeting Agents: A SNAP-tag-Based High-Content Screening Assay for the Analysis of Microtubule Dynamics and Cell Cycle Progression.
    SLAS discovery : advancing life sciences R & D, 2017, Volume: 22, Issue:4

    Topics: A549 Cells; Antineoplastic Agents; Cell Cycle; Dose-Response Relationship, Drug; Drug Discovery; Guanine; High-Throughput Screening Assays; Humans; Microtubules; Nocodazole; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Small Molecule Libraries; Tubulin; Tubulin Modulators

2017
Regulation of spindle integrity and mitotic fidelity by BCCIP.
    Oncogene, 2017, 08-17, Volume: 36, Issue:33

    Topics: Animals; Calcium-Binding Proteins; Cell Cycle Proteins; Centrioles; Centrosome; Chromosome Segregation; Dynactin Complex; Dyneins; HEK293 Cells; HeLa Cells; Humans; Mice; Microtubules; Mitosis; Nocodazole; Nuclear Proteins; Paclitaxel; Protein Isoforms; Spindle Poles; Tubulin Modulators

2017
3D motion of vesicles along microtubules helps them to circumvent obstacles in cells.
    Journal of cell science, 2017, Jun-01, Volume: 130, Issue:11

    Topics: Animals; Cell Line; Chlorocebus aethiops; Cytoplasmic Vesicles; Cytoskeleton; Epithelial Cells; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Luminescent Proteins; Lysosomal-Associated Membrane Protein 2; Lysosomes; Microspheres; Microtubules; Nocodazole; Optical Imaging; Paclitaxel; Recombinant Fusion Proteins; Red Fluorescent Protein; Tubulin

2017
High-throughput cell mechanical phenotyping for label-free titration assays of cytoskeletal modifications.
    Cytoskeleton (Hoboken, N.J.), 2017, Volume: 74, Issue:8

    Topics: Actins; Biomechanical Phenomena; Chromatin; Computer Systems; Cytochalasin D; Cytoskeleton; Depsipeptides; High-Throughput Screening Assays; HL-60 Cells; Humans; Hydroxamic Acids; Microtubules; Nocodazole; Paclitaxel; Phenotype; Staining and Labeling

2017
Pixuna virus modifies host cell cytoskeleton to secure infection.
    Scientific reports, 2017, 07-18, Volume: 7, Issue:1

    Topics: Alphavirus; Animals; Chlorocebus aethiops; Cytochalasin D; Cytoskeleton; Depsipeptides; Host-Pathogen Interactions; Microtubules; Nocodazole; Paclitaxel; Time Factors; Tubulin Modulators; Vero Cells; Virus Replication

2017
Tubulin is retained throughout the human hematopoietic/erythroid cell differentiation process and plays a structural role in sedimentable fraction of mature erythrocytes.
    The international journal of biochemistry & cell biology, 2017, Volume: 91, Issue:Pt A

    Topics: Adult; Blood Sedimentation; Erythrocytes; Female; Hematopoiesis; Humans; Male; Nocodazole; Paclitaxel; Spectrin; Tubulin

2017
NQO2 inhibition relieves reactive oxygen species effects on mouse oocyte meiotic maturation and embryo development.
    Biology of reproduction, 2017, Oct-01, Volume: 97, Issue:4

    Topics: Animals; Antifibrinolytic Agents; Beclin-1; Embryo, Mammalian; Gene Expression Regulation, Enzymologic; Malondialdehyde; Meiosis; Melatonin; Mice; Nocodazole; Oocytes; Paclitaxel; Parthenogenesis; Protein Transport; Pyridines; Pyrrolizidine Alkaloids; Quinone Reductases; Reactive Oxygen Species; Tubulin Modulators; Vitamin K 3

2017
Aurora A kinase activity is required to maintain an active spindle assembly checkpoint during prometaphase.
    Journal of cell science, 2018, 04-12, Volume: 131, Issue:7

    Topics: Anaphase; Aurora Kinase A; Azepines; Cell Line, Tumor; Chromatids; Chromosome Segregation; Gene Expression Regulation, Enzymologic; Humans; Kinetochores; M Phase Cell Cycle Checkpoints; Mad2 Proteins; Microtubules; Mitosis; Nocodazole; Paclitaxel; Prometaphase; Pyrimidines; Spindle Apparatus

2018
Cognitive impairment in a rat model of neuropathic pain: role of hippocampal microtubule stability.
    Pain, 2018, Volume: 159, Issue:8

    Topics: Animals; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Learning; Long-Term Potentiation; Male; Memory; Microtubules; Neuralgia; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Tubulin Modulators

2018
Cyclin-dependent kinase 1-mediated phosphorylation of YES links mitotic arrest and apoptosis during antitubulin chemotherapy.
    Cellular signalling, 2018, Volume: 52

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; CDC2 Protein Kinase; Drug Resistance, Neoplasm; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-yes; Tubulin Modulators

2018
Response of head and neck epithelial cells to a DNA damage-differentiation checkpoint involving polyploidization.
    Head & neck, 2018, Volume: 40, Issue:11

    Topics: Biopsy, Needle; Cell Cycle Checkpoints; Cell Proliferation; Cells, Cultured; Cyclin E; DNA Damage; Doxorubicin; Epithelial Cells; Female; Humans; Keratinocytes; Male; Nocodazole; Oncogene Proteins; Paclitaxel; Real-Time Polymerase Chain Reaction; Sensitivity and Specificity; Squamous Cell Carcinoma of Head and Neck

2018
Microtubules play a role in trafficking prevacuolar compartments to vacuoles in tobacco pollen tubes.
    Open biology, 2018, 10-31, Volume: 8, Issue:10

    Topics: Cell Membrane; Dinitrobenzenes; Endocytosis; Endosomes; Golgi Apparatus; Microtubules; Nicotiana; Nocodazole; Paclitaxel; Pollen Tube; Sulfanilamides; Vacuoles; Wortmannin

2018
Association of cell cycle arrest with anticancer drug-induced epithelial-mesenchymal transition in alveolar epithelial cells.
    Toxicology, 2019, 08-01, Volume: 424

    Topics: A549 Cells; Actins; Alveolar Epithelial Cells; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Cycle Checkpoints; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Humans; Methotrexate; Nocodazole; Paclitaxel; Thymidine

2019
Chromosomally unstable tumor cells specifically require KIF18A for proliferation.
    Nature communications, 2021, 02-22, Volume: 12, Issue:1

    Topics: Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Proliferation; Centrosome; Chromosomal Instability; Humans; Kinesins; Microtubules; Mitosis; Models, Biological; Neoplasms; Nocodazole; Paclitaxel; Spindle Apparatus

2021
Microtubules and Dynein Regulate Human Neutrophil Nuclear Volume and Hypersegmentation During
    Frontiers in immunology, 2021, Volume: 12

    Topics: Cell Nucleus; Cells, Cultured; Centrosome; Dyneins; Helicobacter Infections; Helicobacter pylori; Humans; Intravital Microscopy; Microtubules; Neutrophils; Nocodazole; Paclitaxel; Primary Cell Culture; Tubulin Modulators

2021
Bidirectional role of microtubule dynamics in the acquisition and maintenance of temporal information in dorsolateral striatum.
    Neurobiology of learning and memory, 2021, Volume: 183

    Topics: Animals; Corpus Striatum; Learning; Microtubule Proteins; Microtubules; Neostriatum; Neuronal Plasticity; Nocodazole; Paclitaxel; Rats; Time Perception; Tubulin Modulators

2021