nocodazole and leupeptins

nocodazole has been researched along with leupeptins in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's3 (13.04)18.2507
2000's10 (43.48)29.6817
2010's9 (39.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greenberg, PL; Rozengurt, E1
Haass, C; Hung, AY; Oltersdorf, T; Schlossmacher, MG; Selkoe, DJ; Teplow, DB1
Davis, EC; Mecham, RP1
Arlot-Bonnemains, Y; Chartrain, I; Philippe, M; Uzbekov, R1
Chen, I; Cheung, A; Limouze, J; Mitchison, TJ; Sellers, JR; Straight, AF; Westwood, NJ1
Doi, H; Jana, NR; Kim, K; Maruyama, M; Mitsui, K; Nagaoka, U; Nukina, N; Oyama, F1
Dvorák, Z; Maurel, P; Modrianský, M; Pascussi, JM; Ulrichová, J; Vilarem, MJ1
Burns, AR; Eissa, NT; Kolodziejska, KE; Moore, RH; Stenoien, DL1
Chinnappan, D; Nguyen, HG; Ravid, K; Urano, T1
Gorbsky, GJ; Yamada, HY1
Bauer, NG; Richter-Landsberg, C1
Hällbrink, M; Jayamanne, M; Kjellander, M; Palm, C1
Hatakeyama, K; Hirota, T; Kumada, K; Nakajima, M; Noda, T; Peters, JM1
Goldbaum, O; Jensen, PH; Richter-Landsberg, C1
Dou, Z; Dulla, K; Elowe, S; Li, X; Nigg, EA; Uldschmid, A1
Sluder, G; Uetake, Y1
Foley, EA; Kapoor, TM; Maldonado, M1
Balmanno, K; Clark, J; Cook, SJ; Gilley, R; Lochhead, PA; Oxley, D1
Hoffmann, S; Kubiak, JZ; Maro, B; Polanski, Z1
Jaakkola, K; Kallio, L; Kallio, MJ; Kukkonen-Macchi, A; Mäki-Jouppila, J; Pouwels, J; Salmela, AL; Toivonen, P; Waris, S1
Chang, WL; Chen, CS; Guh, JH; Yu, CC1
Ge, Y; Rana, ASJB; Strieter, ER1
Chen, Y; Liu, H; Qu, Q; Yang, L; Zhang, Q1

Other Studies

23 other study(ies) available for nocodazole and leupeptins

ArticleYear
Role of intracellular degradation of epidermal growth factor in mitogenesis.
    Experimental cell research, 1982, Volume: 142, Issue:1

    Topics: Animals; Benzimidazoles; Cell Membrane; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Epidermal Growth Factor; Leupeptins; Methylamines; Mice; Mitosis; Nocodazole

1982
Normal cellular processing of the beta-amyloid precursor protein results in the secretion of the amyloid beta peptide and related molecules.
    Annals of the New York Academy of Sciences, 1993, Sep-24, Volume: 695

    Topics: Amino Acid Sequence; Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Brefeldin A; Cell Line; Colchicine; Cyclopentanes; Golgi Apparatus; Humans; Kidney; Leupeptins; Lysosomes; Molecular Sequence Data; Monensin; Nocodazole; Protein Processing, Post-Translational; Transfection

1993
Selective degradation of accumulated secretory proteins in the endoplasmic reticulum. A possible clearance pathway for abnormal tropoelastin.
    The Journal of biological chemistry, 1996, Feb-16, Volume: 271, Issue:7

    Topics: Ammonium Chloride; Animals; Blotting, Northern; Brefeldin A; Cattle; Cells, Cultured; Cycloheximide; Cyclopentanes; Endoplasmic Reticulum; Leucine; Leupeptins; Ligaments; Microscopy, Electron; Nocodazole; Organelles; Protein Synthesis Inhibitors; RNA, Messenger; Serine Proteinase Inhibitors; Transcription, Genetic; Tropoelastin

1996
Cell cycle analysis and synchronization of the Xenopus cell line XL2.
    Experimental cell research, 1998, Jul-10, Volume: 242, Issue:1

    Topics: Animals; Aphidicolin; Cell Cycle; Cell Line; Cyclin B; Leupeptins; Mitosis; Nocodazole; S Phase; Tubulin; Xenopus laevis

1998
Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor.
    Science (New York, N.Y.), 2003, Mar-14, Volume: 299, Issue:5613

    Topics: Anaphase; Aurora Kinases; Cell Division; Cell Movement; Contractile Proteins; Cyclin-Dependent Kinases; DNA Replication; Enzyme Inhibitors; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Kinesins; Leupeptins; Microtubules; Mitosis; Myosin Type II; Nocodazole; Protein Serine-Threonine Kinases; Staurosporine; Ubiquitin

2003
Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions.
    Journal of neurochemistry, 2004, Volume: 91, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain; Carrier Proteins; Cell Count; Cell Fractionation; Cell Line, Tumor; Cell Nucleus; Chromatography, High Pressure Liquid; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Drug Interactions; Exons; Fluorescent Antibody Technique; Gene Expression Regulation; Green Fluorescent Proteins; Huntingtin Protein; Immunoblotting; Immunoprecipitation; Inclusion Bodies; Indoles; Leupeptins; Male; Mass Spectrometry; Mice; Mice, Knockout; Nerve Tissue Proteins; Neuroblastoma; Neurons; Nocodazole; Nuclear Proteins; Peptides; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Sequence Analysis, Protein; Time Factors; Transcription Factor TFIIH; Transcription Factors; Transfection; Ubiquitin

2004
Disruption of microtubules leads to glucocorticoid receptor degradation in HeLa cell line.
    Cellular signalling, 2005, Volume: 17, Issue:2

    Topics: Animals; Anthracenes; Chlorocebus aethiops; Colchicine; COS Cells; Cysteine Proteinase Inhibitors; Cytosol; Dexamethasone; Enzyme Inhibitors; HeLa Cells; Humans; Intranuclear Space; JNK Mitogen-Activated Protein Kinases; Leupeptins; Microtubules; Mutation; NF-kappa B; Nocodazole; Proteasome Endopeptidase Complex; Protein Transport; Receptors, Glucocorticoid; Transfection; Ubiquitin; Vincristine

2005
Regulation of inducible nitric oxide synthase by aggresome formation.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Mar-29, Volume: 102, Issue:13

    Topics: Animals; Cells, Cultured; Dyneins; Fluorescence Recovery After Photobleaching; Green Fluorescent Proteins; Humans; Image Processing, Computer-Assisted; Inclusion Bodies; Indoles; Leupeptins; Mice; Microscopy, Electron; Microtubule-Organizing Center; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nocodazole

2005
Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property.
    Molecular and cellular biology, 2005, Volume: 25, Issue:12

    Topics: Amino Acid Motifs; Anaphase-Promoting Complex-Cyclosome; Aneuploidy; Animals; Antineoplastic Agents; Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome; Aurora Kinase B; Aurora Kinases; Cdc20 Proteins; Cell Cycle; Cell Cycle Proteins; Chromosomes; Cysteine Proteinase Inhibitors; HeLa Cells; Humans; Leupeptins; Molecular Sequence Data; Nocodazole; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Ubiquitin; Ubiquitin-Protein Ligase Complexes

2005
Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; ATPases Associated with Diverse Cellular Activities; Cysteine Proteinase Inhibitors; HeLa Cells; Humans; Leupeptins; LIM Domain Proteins; Mitosis; Nocodazole; Paclitaxel; Peptide Fragments; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Spindle Apparatus; Transcription Factors

2006
The dynamic instability of microtubules is required for aggresome formation in oligodendroglial cells after proteolytic stress.
    Journal of molecular neuroscience : MN, 2006, Volume: 29, Issue:2

    Topics: Alternative Splicing; Cell Line; Crystallins; Cysteine Proteinase Inhibitors; Heat-Shock Proteins; Humans; Inclusion Bodies; Leupeptins; Microtubule-Organizing Center; Microtubules; Mitochondria; Nocodazole; Oligodendroglia; Oxidative Stress; Paclitaxel; Protein Isoforms; tau Proteins; Tubulin Modulators; Ubiquitin

2006
Peptide degradation is a critical determinant for cell-penetrating peptide uptake.
    Biochimica et biophysica acta, 2007, Volume: 1768, Issue:7

    Topics: Androstadienes; Animals; Carrier Proteins; Cell Membrane; Cell-Penetrating Peptides; Chloroquine; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cytochalasin B; Deoxyglucose; Endocytosis; Leupeptins; Membrane Glycoproteins; Models, Biological; Nocodazole; Oligopeptides; Peptide Fragments; Peptides; Perforin; Phenanthrolines; Phenylmethylsulfonyl Fluoride; Pore Forming Cytotoxic Proteins; Protease Inhibitors; Protein Transport; Sodium Azide; Wortmannin

2007
The complete removal of cohesin from chromosome arms depends on separase.
    Journal of cell science, 2007, Dec-01, Volume: 120, Issue:Pt 23

    Topics: 3T3 Cells; Animals; Antibodies, Monoclonal; Azure Stains; Cell Cycle Proteins; Cell Line, Transformed; Chromosomal Proteins, Non-Histone; Chromosomes, Human; Cohesins; Endopeptidases; Enzyme Inhibitors; Fibroblasts; Humans; Leupeptins; Mice; Mitosis; Models, Genetic; Nocodazole; Nuclear Proteins; Proteasome Inhibitors; RNA Interference; RNA, Small Interfering; Separase; Sister Chromatid Exchange; Spindle Apparatus

2007
The expression of tubulin polymerization promoting protein TPPP/p25alpha is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress.
    Glia, 2008, Volume: 56, Issue:16

    Topics: Animals; Brain; Carrier Proteins; Cell Differentiation; Cells, Cultured; Centrosome; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Inclusion Bodies; Leupeptins; Nerve Tissue Proteins; Nocodazole; Oligodendroglia; Peptide Hydrolases; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Rats, Wistar; Tubulin; Tubulin Modulators; Up-Regulation

2008
Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.
    Journal of cell science, 2010, Jan-01, Volume: 123, Issue:Pt 1

    Topics: Amino Acid Motifs; CDC2 Protein Kinase; Cdc20 Proteins; Cell Cycle Proteins; Cysteine Proteinase Inhibitors; Genes, cdc; HeLa Cells; Humans; Kinetochores; Leupeptins; Mitosis; Mutation; Nocodazole; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein Transport; Spindle Apparatus; Tubulin Modulators

2010
Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis.
    Current biology : CB, 2010, Sep-28, Volume: 20, Issue:18

    Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Humans; Leupeptins; Mitosis; Nocodazole; Prometaphase

2010
Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase.
    Nature cell biology, 2011, Aug-28, Volume: 13, Issue:10

    Topics: Aurora Kinase B; Aurora Kinases; Benzamides; Cell Cycle Proteins; Chromosome Segregation; HeLa Cells; Humans; Indoles; Kinetochores; Leupeptins; Microscopy, Fluorescence; Microtubules; Nocodazole; Phosphorylation; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Quinazolines; Recombinant Fusion Proteins; RNA Interference; Sulfonamides; Time Factors; Transfection; Tumor Suppressor Proteins

2011
CDK1, not ERK1/2 or ERK5, is required for mitotic phosphorylation of BIMEL.
    Cellular signalling, 2012, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; CDC2 Protein Kinase; Cell Cycle Checkpoints; Enzyme Activation; Enzyme Assays; Genes, Reporter; HEK293 Cells; Humans; Leupeptins; Luciferases, Renilla; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 7; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteolysis; Proto-Oncogene Proteins; Recombinant Fusion Proteins

2012
A single bivalent efficiently inhibits cyclin B1 degradation and polar body extrusion in mouse oocytes indicating robust SAC during female meiosis I.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Animals; Chromosome Segregation; Chromosomes, Mammalian; Cyclin B1; Cysteine Proteinase Inhibitors; Female; Green Fluorescent Proteins; Kinetics; Kinetochores; Leupeptins; M Phase Cell Cycle Checkpoints; Meiosis; Mice; Microscopy, Fluorescence; Microtubules; Nocodazole; Oocytes; Polar Bodies; Proteolysis

2011
The flavonoid eupatorin inactivates the mitotic checkpoint leading to polyploidy and apoptosis.
    Experimental cell research, 2012, Mar-10, Volume: 318, Issue:5

    Topics: Antimitotic Agents; Apoptosis; Aurora Kinase B; Aurora Kinases; Cell Culture Techniques; Cell Proliferation; Centrosome; Flavonoids; HeLa Cells; High-Throughput Screening Assays; Humans; Leupeptins; M Phase Cell Cycle Checkpoints; Male; Microscopy, Fluorescence; Nocodazole; Polyploidy; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Thiones; Time-Lapse Imaging

2012
Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells – a critical role of Cdk1 in mitotic entry.
    Biochemical pharmacology, 2015, Mar-01, Volume: 94, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Line, Tumor; Cyclin B1; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Leupeptins; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitosis; Nocodazole; Paclitaxel; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Quinazolines; RNA, Small Interfering; Signal Transduction; Tubulin Modulators; Vincristine

2015
Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry (UbiChEM-MS) Reveals Cell-Cycle Dependent Formation of Lys11/Lys48 Branched Ubiquitin Chains.
    Journal of proteome research, 2017, 09-01, Volume: 16, Issue:9

    Topics: Amino Acid Sequence; Aminopyridines; Deubiquitinating Enzymes; HEK293 Cells; Humans; Leupeptins; Lysine; Mass Spectrometry; Mitosis; Nocodazole; Polyubiquitin; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Thiocyanates; Ubiquitin

2017
SET binding to Sgo1 inhibits Sgo1-cohesin interactions and promotes chromosome segregation.
    The Journal of cell biology, 2019, 08-05, Volume: 218, Issue:8

    Topics: Cell Cycle Checkpoints; Cell Cycle Proteins; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Cohesins; DNA-Binding Proteins; HeLa Cells; Histone Chaperones; Humans; Kinetochores; Leupeptins; Models, Biological; Mutant Proteins; Nocodazole; Protein Binding; Protein Domains

2019