nocodazole has been researched along with colchicine in 271 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 76 (28.04) | 18.7374 |
| 1990's | 86 (31.73) | 18.2507 |
| 2000's | 67 (24.72) | 29.6817 |
| 2010's | 38 (14.02) | 24.3611 |
| 2020's | 4 (1.48) | 2.80 |
| Authors | Studies |
|---|---|
| Baasner, S; Beckers, T; Böhmer, FD; Burger, AM; Bürgermeister, J; Fiebig, HH; Frieser, M; Hockemeyer, J; Hufsky, H; Lyssenko, A; Mahboobi, S; Paper, DH; Pongratz, H | 1 |
| Burger, AM; Camacho Gomez, JA; Düssmann, H; Günther, EG; Hirano, T; Ishii, Y; Prehn, JH; Prinz, H; Schmidt, P; Stoiber, T; Umezawa, K; Unger, E | 1 |
| Baasner, S; Böhm, KJ; Gerlach, M; Günther, EG; Müller, K; Prinz, H; Schmidt, P; Unger, E; Zuse, A | 2 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Baasner, S; Böhm, KJ; Gerlach, M; Günther, EG; Müller, K; Prinz, H; Schmidt, P; Unger, E | 2 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Hergenrother, PJ; Miller, MJ; Miller, PA; Moraski, GC; Palchaudhuri, R; Peterson, RJ; Stefely, JA | 1 |
| Baasner, S; Böhm, KJ; Gerlach, M; Günther, EG; Müller, K; Nickel, HC; Prinz, H; Schmidt, P; Unger, E | 1 |
| Böhm, KJ; Müller, K; Prinz, H; Surkau, G | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Aicher, B; Amon, P; Böhm, KJ; Chamasmani, B; Gerlach, M; Günther, EG; Ivanov, I; Müller, K; Prinz, H; Vogel, K | 1 |
| Lama, R; Li, B; Sandhu, R; Su, B; Zhong, B | 1 |
| Addlagatta, A; Jain, N; Kalivendi, SV; Kishor, C; Kumar, AS; Murthy, TR; Ramesh, D; Reddy, MA; Sreedhar, B; Supriya, B | 1 |
| Asthana, J; Chakraborty, TK; Gajula, PK; Panda, D | 1 |
| Akula, B; Bharathi, EV; Billa, VK; Cosenza, SC; Gallo, JM; Lv, H; Mallireddigari, MR; Padgaonkar, A; Pallela, VR; Reddy, EP; Reddy, MV; Subbaiah, DR | 1 |
| Camarasa, MJ; Canela, MD; Díaz, JF; Liekens, S; Noppen, S; Pérez-Pérez, MJ; Priego, EM; Sáez-Calvo, G | 1 |
| Antus, S; Bai, R; Basso, G; Bényei, AC; Hamel, E; Porcù, E; Schmidhammer, H; Sipos, A; Stempfer, V; Udvardy, A; Viola, G | 1 |
| Addlagatta, A; Dayakar, Ch; Kalivendi, SV; Kishor, C; Murthy, TR; Rajkumar, K; Raju, BC; Srikanth, D; Suman, P | 1 |
| Capuano, B; DeBono, A; Scammells, PJ | 1 |
| Asai, A; Ishii, H; Kuroiwa, K; Matsuno, K; Suzuki, Y | 1 |
| Bantu, R; Gurrala, S; Jain, N; Nagarapu, L; Polepalli, S; Srujana, G; Yadagiri, B | 1 |
| Meegan, MJ; Nathwani, S; O'Boyle, NM; Twamley, B; Zisterer, DM | 1 |
| Aghaee, E; Böhm, KJ; Ghasemi, JB; Ivanov, I; Müller, K; Prinz, H; Ridder, AK; Vogel, K | 1 |
| Briguglio, I; Carta, A; Corona, P; Fermeglia, M; Laurini, E; Piras, S; Pirisi, MA; Pricl, S | 1 |
| Alfano, G; Altucci, L; Amet, R; Baldari, C; Barasoain, I; Brindisi, M; Brogi, S; Butini, S; Campiani, G; Chemi, G; Conte, M; de Asís Balaguer, F; Diaz, JF; Gemma, S; Grillo, A; Ibrahim, O; Khan, T; Kinsella, P; Lopresti, L; Lucena-Agell, D; Magnano, S; Menchon, G; Morbidelli, L; Nebbioso, A; Novellino, E; O'Sullivan, J; Olieric, N; Prota, AE; Spaccapelo, R; Steinmetz, MO; Ulivieri, C; Zisterer, DM | 1 |
| He, L; Tang, YJ; Xiang, TL; Zhao, W | 1 |
| Kaieda, A; Kokubu, Y; Miyamoto, K; Miyamoto, M; Nagino, T; Oikawa, T; Oki, A; Saito, B; Sakurai, H; Sameshima, T; Sasa, K; Takada, H; Tawada, M; Tozawa, R | 1 |
| Ahlfeld, J; Bracher, F; Gao, L; Glas, C; Heise, C; Kraus, Y; Melzer, B; Preuße, M; Thorn-Seshold, O | 1 |
| Aghaee, E; Daniliuc, CG; Ghasemi, JB; Ivanov, I; Müller, K; Prinz, H; Waltemate, J | 1 |
| Braga, H; Campbell, D; Chen, F; Forgione, P; Jaunky, DB; Larocque, K; Liu, JT; Mckibbon, K; Piekny, A; Shafeii, A; Sirouspour, M; Taylor, S | 1 |
| Ojakian, GK; Schwimmer, R | 1 |
| Aplin, A; Dunn, WA; Jasionowski, T; Lenk, SE; Tuttle, DL | 1 |
| Bartfeld, NS; Baynham, P; Levin, EG; Marotti, K; Santell, L | 1 |
| Dahms, NM; Ramanujam, KS; Seetharam, B; Seetharam, S | 1 |
| Ballmer-Hofer, K; Botteri, FM; Nagamine, Y; Rajput, B | 1 |
| Wheatley, DN | 1 |
| Bouanga, JC; Durand-Schneider, AM; Feldmann, G; Maurice, M | 1 |
| Chochillon, C; Favennec, L; Gobert, JG; Gorenflot, A; Kapel, N; Magne, D; Meillet, D; Raichvarg, D; Savel, J | 1 |
| Gilbert, T; Rodriguez-Boulan, E | 1 |
| Ashton, AC; Dolly, JO | 2 |
| Fattori, E; Moll, J; Sansig, G; van der Putten, H | 1 |
| Blomgren, K; Thyberg, J | 1 |
| Keller, HU | 1 |
| Clark, CL; Taylor, MJ | 1 |
| Gordon, AH; Hart, PD; Young, MR | 1 |
| Austin, RC; Dudani, AK; Gupta, RS; Venner, TJ | 1 |
| Longo, FJ; Luttmer, SJ | 1 |
| Fujiwara, K; McBeath, E | 1 |
| Anstrom, JA | 1 |
| Berman, JD; Middleton, W; Ray, P | 1 |
| Boisvieux-Ulrich, E; Lainé, MC; Sandoz, D | 1 |
| Foster, KE; Gull, K; Prescott, AR; Warn, RM | 1 |
| Haase, W; Kondor-Koch, C; Parczyk, K | 1 |
| Bourguet, J; Hugon, JS; Ibarra, C; Valenti, G | 1 |
| Meijer, L; Pondaven, P | 1 |
| Fredholm, BB; Kvanta, A; Nordstedt, C | 1 |
| Kreutzberg, GW; Lucas, CA | 1 |
| Menon, KM; Rajan, VP | 1 |
| Keller, HU; Zimmermann, A | 1 |
| Cereijido, M; Gundersen, D; Misek, DE; Rodriguez-Boulan, E; Salas, PJ; Vega-Salas, DE | 1 |
| Carnegie, JA; Dardick, I; Tsang, BK | 1 |
| Alvarado, J; Polansky, J; Ryder, MI; Weinreb, RN | 1 |
| Boisvieux-Ulrich, E; Chailley, B; Laine, MC; Lemullois, M; Sandoz, D | 1 |
| Ken, J; Wolf, P | 1 |
| de Brabander, M; Geuens, GM; Houdebine, LM; Martel, P; Servely, JL | 1 |
| Burgoyne, RD; Cambray-Deakin, MA; Robson, SJ | 1 |
| Licht, P; Porter, DA | 1 |
| Battaglia, DE; Schroeder, TE | 1 |
| Bourguet, J; Hugon, JS; Valenti, G | 1 |
| Elinson, RP; Rowning, B | 1 |
| Sinha, S; Wagner, DD | 1 |
| Moskalewski, S; Thyberg, J | 1 |
| Branch, WJ; Luzio, JP; Mullock, BM; Perez, JH; Smith, L | 1 |
| Dore-Duffy, P; Zurier, RB | 1 |
| Bowser, SS; Travis, JL | 2 |
| Bennett, G; Hugon, JS; Ngoma, Z; Pothier, P | 1 |
| LeDizet, M; Piperno, G | 1 |
| Smedley, MJ; Stanisstreet, M | 1 |
| Gupta, RS | 2 |
| Bowser, SS; Rieder, CL | 1 |
| Bane, S; Ludueña, RF; Roach, MC | 1 |
| Langford, GM; Luduena, RF; MacRae, TH; Roach, MC | 1 |
| Hall, PF; Osawa, S | 1 |
| Aizenman, E; Carlson, KE; Price, CH | 1 |
| Albertini, DF; Clark, JI | 1 |
| Hamel, E; Lin, CM | 2 |
| Cleveland, DW; Kirschner, MW; Lopata, MA; Sherline, P | 1 |
| Christen, P; Jaussi, R; Skoda, RC | 1 |
| Albertini, DF; Herman, B; Langevin, MA | 1 |
| Cohen, WD; Joseph-Silverstein, J | 1 |
| Luftig, RB; Satake, M | 1 |
| Cleveland, DW; Lopata, MA; Pittenger, MF | 1 |
| Rozengurt, E; Wang, ZW | 1 |
| Jimenez de Asua, L; Otto, AM | 1 |
| Coote, JE; Humphray, HP; Skidmore, IF | 1 |
| Keller, HU; Naef, A; Zimmermann, A | 1 |
| Crawford, EJ; Friedkin, M | 1 |
| Gerhart, J; Kirschner, M; Wu, M | 1 |
| Mesland, DA; Spiele, H | 1 |
| Abé, S; Uno, S | 1 |
| Ludueña, RF; Roach, MC | 1 |
| Fleit, HB | 1 |
| Brun, RB; Garson, JA | 1 |
| Pickett-Heaps, J; Spurck, T; Tippit, D | 1 |
| Fernandez, SM; Herman, BA | 1 |
| Adamson, DJ; Bowdon, BJ; Temple, C; Webster, J; Wheeler, GP | 1 |
| Gull, K; Pogson, CI; Quinlan, RA; Roobol, A | 1 |
| Roos, E; Van de Pavert, IV | 1 |
| Magendantz, M; Solomon, F | 1 |
| Kilmartin, JV | 1 |
| Chalfie, M; Thomson, JN | 1 |
| Hedin, U; Stenseth, K; Thyberg, J | 1 |
| Armelin, HA; Farias, SE | 1 |
| Black, PH; Chou, IN; Solomon, JA; Zeiger, J | 1 |
| Cappuccinelli, P; Fogu, G; Rubino, S; Unger, E | 1 |
| Schrek, R; Stefani, SS | 1 |
| Brady, RJ; Coluccio, LM; Parsons, RH | 1 |
| DeStefano, MJ; Dziezanowski, MA; Rabinovitch, M | 1 |
| Cheung, HT; Terry, DS | 1 |
| Forstner, GG; Forstner, JF; McCool, DJ | 1 |
| Bayraktutan, U; Jones, P | 1 |
| Holm, PK; Kayser, L; Sandvig, K; van Deurs, B | 1 |
| Chen, JG; Kempson, SA; Strawbridge, AB | 1 |
| Beron, W; Dusso, A; Gallieni, M; Kamimura, S; Slatopolsky, E; Zhong, M | 1 |
| Catravas, JD; Jilling, T; Marczin, N; Papapetropoulos, A | 1 |
| de Médicis, R; Gaudry, M; Lussier, A; Naccache, PH; Poubelle, PE; Roberge, CJ | 1 |
| Banati, RB; Beyreuther, K; Masters, CL; Mönning, U; Sandbrink, R; Weidemann, A | 1 |
| Arena, N; Baroni, T; Becchetti, E; Carinci, P; Evangelisti, R; Locci, P; Rossi, L; Valeno, V | 1 |
| Chan, CK; Czaban, B; Downey, GP; Grinstein, S; Sue-A-Quan, A | 1 |
| Andrews, SB; Kidd, GJ; Trapp, BD | 1 |
| Erusalimsky, JD; Hancock, V; Hong, Y; Martin, JF; van der Loo, B | 1 |
| Allan, AM; Harris, RA; McQuilkin, SJ; Mihic, SJ; Whatley, VJ | 1 |
| Bugnoli, M; de Bernard, M; Milia, E; Montecucco, C; Papini, E; Rappuoli, R; Zerial, M | 1 |
| Smith, CL | 1 |
| Raymond, MN; Robin, P; Rossignol, B | 1 |
| Benos, DJ; Bridges, RJ; Fuller, CM | 1 |
| Pless, DD; Thompson, WL; Wellner, RB | 1 |
| Haass, C; Hung, AY; Oltersdorf, T; Schlossmacher, MG; Selkoe, DJ; Teplow, DB | 1 |
| LaVail, JH; Meade, LB; Topp, KS | 1 |
| Klenk, HD; Rott, R; Seto, JT; Tashiro, M | 1 |
| Andrews, SB; Kidd, G; Trapp, BD | 1 |
| Elhajouji, A; Kirsch-Volders, M; Van Hummelen, P | 1 |
| Grassmé, HU; Ireland, RM; van Putten, JP | 1 |
| Demoise, DC; Lee, VM; Merrick, SE | 1 |
| Hacker, J; Korhonen, TK; Meier, C; Merkert, H; Oelschlaeger, TA | 1 |
| Bumbasirević, V; Djuricić, B; Mircić, A; Skaro-Milić, A | 1 |
| Armstrong, L; Bushel, P; Catino, JJ; Kim, JH; Kumar, CC | 1 |
| Aderem, A; Rosen, A; Veis, N | 1 |
| Catravas, JD; Go, C; Jilling, T; Marczin, N; Papapetropoulos, A | 1 |
| Ackerman-Morris, S; Bollenbacher, WE; Smith, WA; Watson, CJ; Watson, RD | 1 |
| Madianos, PN; Papapanou, PN; Sandros, J | 1 |
| Davis, GS; Gemsa, D; Li, Z; Mohr, C; Nain, M | 1 |
| Bilińska, B; Brunswig-Spickenheier, B; Stokłosowa, S | 1 |
| Kennedy, BP; Pruzanski, W; Stefanski, E; Vadas, P; van den Bosch, H | 1 |
| Elhajouji, A; Kirsch-Volders, M; Tibaldi, F | 1 |
| Oelschlaeger, TA; Tall, BD | 1 |
| Limbird, LE; Saunders, C | 1 |
| Asada, S; Goto, K; Hama, H; Inada, T; Kasuya, Y; Ozawa, F | 1 |
| Haraguchi, T; Hiraoka, Y; Kaneda, T | 1 |
| Dupuis, G; Martel, J; Payet, MD | 1 |
| Dondua, AK; Fedorova, ZE; Kostyuchenko, RP | 1 |
| Edeen, KE; Nielsen, LD; Pan, T; Shannon, JM | 1 |
| Rao, GH; White, JG | 1 |
| Fojo, T; Foster, JS; Giannakakou, P; Ichijo, H; Wang, HS; Wang, TH; Wimalasena, J | 1 |
| Benos, DJ; Morris, RG; Schafer, JA; Tousson, A | 1 |
| Kuhn, M | 1 |
| Cunha, M; Elhajouji, A; Kirsch-Volders, M | 1 |
| Clauss, W; Rehn, M; Weber, WM | 1 |
| Kidokoro, Y; Kuromi, H | 1 |
| Bueno, OF; Leidenheimer, NJ | 1 |
| Connors, SA; Kanatsu-Shinohara, M; Kopf, GS; Schultz, RM | 1 |
| Garduño, RA; Hoffman, PS; Quinn, FD | 1 |
| Gerke, V; Kielbassa, K; Schmitz, C | 1 |
| Abrieu, A; Dorée, M; Fotedar, R; Job, D; Margolis, RL; Saoudi, Y; Wehland, J | 1 |
| Jordan, MA; Wilson, L | 1 |
| Capen, CC; Gröne, A; Rosol, TJ; Weckmann, MT | 1 |
| Chaudhuri, AR; Curcio, M; Ludueña, RF; Mizuhashi, F; Murata, K; Prasad, V; Tomita, I | 1 |
| Hagen, K; Kong, AN; Mandlekar, S; Roninson, IB; Shtil, AA; Tan, TH; Walter, RJ; Yu, R | 1 |
| Candurra, NA; Damonte, EB; Lago, MJ; Maskin, L | 1 |
| Jiang, PS; Yung, BY | 1 |
| Falcone, JC; Hill, MA; Holton, WT; Meininger, GA; Platts, SH | 1 |
| Cohen, E; Ophir, I; Shaul, YB | 1 |
| Leist, M; Nicotera, P; Volbracht, C | 1 |
| Bermudez, LE; Cirillo, JD; Cirillo, SL; Falkow, S; Tompkins, LS; Yan, L | 1 |
| Haier, J; Nasralla, M; Nicolson, GL | 1 |
| Raucher, D; Sheetz, MP | 1 |
| Carmichael, J; Fogarty, KE; Kidd, JF; Skepper, JN; Thorn, P; Turner, A | 1 |
| Dannenberg, AJ; Hart, JC; Norton, L; Subbaramaiah, K | 1 |
| Cherian, SP; Collins, N; Han, EK; Ng, SC; Tahir, SK | 1 |
| Jin, N; Rhoades, RA; Swartz, DR; Yancey, KW; Zhang, D | 1 |
| Isowa, N; Keshavjee, SH; Liu, M | 1 |
| Miller, MG; Strandgaard, CS; Winder, BS | 1 |
| Karbowski, M; Nishizawa, Y; Spodnik, JH; Teranishi, M; Usukura, J; Wakabayashi, T; Wozniak, M | 1 |
| Huang, A; Kaley, G; Koller, A; Sharma, S; Sun, D | 1 |
| Camacho Gomez, JA; Kirschstein, SO; Kittler, L; Neumann, T; Unger, E | 1 |
| Basham, JC; Chabrerie, A; Kempson, SA | 1 |
| Norvell, SM; Pavalko, FM; Ponik, SM; Sawyer, SJ | 1 |
| Jin, N; Li, L; Rhoades, RA; Swartz, DR; Wang, Z; Yancey, KW; Zhang, D | 1 |
| Conrad, GW; Wells, DC | 1 |
| Kucik, DF; Li, J; Zhou, X | 1 |
| Grunenwald, H; Johnson, RG; Laird, DW; Li, XR; Meyer, RA; Paulson, AF; Preus, DM; Sheridan, JD; Tan, L | 1 |
| Blajeski, AL; Kaufmann, SH; Kottke, TJ; Phan, VA | 1 |
| Blagosklonny, MV; Fojo, T; Giannakakou, P; Greber, UF; Nakano, M; Nicolaou, KC; O'Brate, A; Yu, J | 1 |
| Heyder, J; Hofer, T; Karg, E; Möller, W; Ziesenis, A | 1 |
| Ludueña, RF; Xu, K | 1 |
| Hampong, M; Paddon, H; Pelech, S; Shi, X; Wahyuningsih, D; Zhang, H; Zhang, QJ | 1 |
| Kimura, H; Namekata, K; Nishimura, N | 1 |
| Chitaley, K; Webb, RC | 1 |
| Erlandsen, SL; Roskens, H | 1 |
| Bardag-Gorce, F; French, SW; Li, J; Lue, YH; Lungo, W; Montgomery, RO; Riley, NE | 1 |
| Deai, K; Ichikawa, A; Inagaki, M; Tanaka, S | 1 |
| Gibson, W; Irie, S; Kurata, T; Miura, Y; Moriishi, E; Ogawa-Goto, K; Sata, T; Tanaka, K | 1 |
| Biswas, D; Itoh, K; Sasakawa, C | 1 |
| Giehl, K; Goppelt-Struebe, M; Graness, A; Iwanciw, D; Ott, C | 1 |
| Benchimol, M; Madeiro da Costa, RF | 1 |
| Kunz, JB; Mayer, A; Schwarz, H | 1 |
| Häkkinen, L; Koivisto, L; Larjava, H; Matsumoto, K; McCulloch, CA; Yamada, KM | 1 |
| Rula, ME; Smedberg, JL; Smith, ER; Xu, XX | 1 |
| Fujiu, K; Numata, O | 1 |
| Li, L; Sherwood, J; Swartz, DR; Zhang, D | 1 |
| Brum, Cde A; Duarte, ID; Leite, R; Webb, RC | 1 |
| Ichikawa, Y; Ikeda, Y; Kobayashi, H; Miki, T; Miura, T; Nakamura, Y; Nakano, A; Shimamoto, K; Yano, T | 1 |
| Dvorák, Z; Maurel, P; Modrianský, M; Pascussi, JM; Ulrichová, J; Vilarem, MJ | 1 |
| Anderson, M; Chae, KS; Dryer, SE; Martin-Caraballo, M | 1 |
| Hallmann, A; Kedzior, J; Kurono, C; Majczak, A; Masaoka, M; Myśliwski, A; Niemczyk, E; Soji, T; Spodnik, JH; Trzonkowski, P; Wakabayashi, T | 1 |
| Modrianský, M; Vrba, J | 1 |
| Benchimol, M; Mariante, RM; Melo, AL; Vancini, RG | 1 |
| Hori, M; Oka, T; Ozaki, H | 1 |
| Chae, KS; Dryer, SE; Oh, KS | 1 |
| Feng, J; Jiang, H; Jiang, Q; Liu, W; Ren, Y | 1 |
| Burnett, JC; Day, BW; Gussio, R; Hamel, E; Hermone, AR; McGrath, C; Nguyen, TL; Wipf, P; Zaharevitz, DW | 1 |
| Sidhu, A; Wersinger, C | 1 |
| McKeown-Longo, PJ; Zheng, M | 1 |
| de Alaniz, MJ; Marra, CA | 1 |
| Cristofanilli, M; Iacoangeli, A; Muslimov, IA; Tiedge, H | 1 |
| Dvorák, Z; Modrianský, M | 1 |
| Dvorák, Z; Maurel, P; Modriansky, M; Pascussi, JM; Ulrichová, J; Vrzal, R | 1 |
| Aden, SA; Andrews, PM; Bachis, A; Mocchetti, I; Nosheny, RL | 1 |
| Berod, L; Elsner, P; Fluhr, JW; Kaatz, M; Lagadari, M; Norgauer, J | 1 |
| Kasschau, MR; Ngo, TD; Sperber, LM; Tran, KL | 1 |
| Brown, M; Dembowy, J; Pacione, L; Yea, C | 1 |
| Ma, TY; Marchant, JS; Said, HM; Subramanian, VS; Ye, D | 1 |
| Alnemri, ES; Datta, P; Fernandes-Alnemri, T; Juliana, C; McCormick, M; Solorzano, L; Wu, J; Yu, JW; Zhang, Z | 1 |
| Gille, J; Holtmeier, W; Hrgovic, I; Kaprolat, N; Kaufmann, R; Meissner, M; Michailidou, D; Pinter, A; Stein, M | 1 |
| Feng, J; Jiang, H; Nakaso, K; Ren, Y; Yang, F | 1 |
| Fang, M; Nie, Y; Theilmann, DA | 1 |
| Higgins, CE; Higgins, PJ; Higgins, SP; Samarakoon, R | 1 |
| Farrar, D; Jones, S; Mansell, JP; Nowghani, M | 1 |
| Aoki, A; Maldonado, CA; Nishioka, S; Quintar, AA; Torres, AI | 1 |
| Hong, JH; Hur, GM; Jeon, J; Jeong, JE; Kang, SW; Lee, H; Ryu, YS; Shin, S; Zhang, T | 1 |
| Lemasters, JJ; Maldonado, EN; Mullins, MR; Patnaik, J | 1 |
| Abrieu, A; Deshayes, S; Divita, G; Sarli, V; Tcherniuk, S | 1 |
| Belsham, DD; Cheung, S; Fick, LJ; Lovejoy, DA; Thompson, M | 1 |
| Attia, SM | 1 |
| Bando, M; Hiroshima, Y; Inagaki, Y; Kataoka, M; Kido, J; Mihara, C; Murata, H; Nagata, T; Shinohara, Y | 1 |
| Hwang, EM; Jang, D; Jeong, K; Kwon, H; Lee, J; Pak, Y; Park, JY | 1 |
| Anderson, ME; Chen, B; Gao, S; Guo, A; Hong, J; Johnson, FL; Kutschke, W; Miller, JD; Santana, LF; Song, LS; Wehrens, XH; Weiss, RM; Yuan, C; Zhang, C; Zhu, Y; Zimmerman, K | 1 |
| Brown, KD; Ghosh, AK; Giannakakou, P; Harkcom, WT; Jaffrey, SR; Matov, A; Sung, MS | 1 |
| Asiedu, MN; Dussor, G; Ghosh, S; Mandell, EK; Melemedjian, OK; Moy, JK; Price, TJ; Tillu, DV | 1 |
| Alain, T; Arulanandam, R; Atkins, H; Babawy, A; Batenchuk, C; Bell, JC; Chen, A; Conrad, DP; Cox, J; Davis, C; De Silva, N; Diallo, JS; Falls, T; Forbes, NE; Garcia, V; Garson, K; Hamill, J; Ilkow, C; Karmacharya, R; Krishnan, R; Kærn, M; Le Boeuf, F; Sinha, A; Sonenberg, N; Vanderhyden, B; Varette, O; Waite, K; Weinstein, E; Zakaria, C | 1 |
| Harris, WA; Holt, CE; Lee, AC; Lu, TB; McNeilly, H; Piper, M; van Horck, FP | 1 |
| Casanelles, E; Garcia-Belinchón, M; Granados-Colomina, C; Iglesias-Guimarais, V; Martínez-Escardó, L; Pascual-Guiral, S; Ribas, J; Sánchez-Osuna, M; Yuste, VJ | 1 |
| Chen, Q; Chen, X; Gigant, B; Lai, Q; Wang, Y; Wu, Y; Yang, J; Yang, Z; Yu, Y; Zhang, H | 1 |
| Bodakuntla, S; Chandra, A; Das, R; Janke, C; Jijumon, AS; Kesarwani, S; Lama, P; Rao, BM; Reddy, PP; Sirajuddin, M | 1 |
2 review(s) available for nocodazole and colchicine
| Article | Year |
|---|---|
Development and functions of the cytoskeleton during ciliogenesis in metazoa.
Topics: Alkaloids; Animals; Benzimidazoles; Centrioles; Cilia; Colchicine; Cytochalasin D; Cytochalasins; Cytoskeleton; Diazepam; Epithelium; Morphogenesis; Nocodazole; Paclitaxel; Quail | 1988 |
Microtubule disruptors and their interaction with biotransformation enzymes.
Topics: Antimitotic Agents; Biotransformation; Colchicine; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Microtubules; Nocodazole; Paclitaxel; Receptors, Aryl Hydrocarbon; Receptors, Glucocorticoid; Signal Transduction; Vinblastine; Vincristine | 2005 |
269 other study(ies) available for nocodazole and colchicine
| Article | Year |
|---|---|
Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents.
Topics: Allantois; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Biopolymers; Cattle; Chorion; Drug Screening Assays, Antitumor; G2 Phase; GTP Phosphohydrolases; Humans; In Vitro Techniques; Indoles; Melanoma; Mice; Mice, Nude; Mitosis; Structure-Activity Relationship; Transplantation, Heterologous; Tubulin; Tumor Cells, Cultured | 2001 |
Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Biopolymers; Blotting, Western; Cell Cycle; Cell Survival; Drug Screening Assays, Antitumor; Humans; K562 Cells; Microscopy, Electron; Structure-Activity Relationship; Tubulin | 2003 |
9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Proliferation; Cell Survival; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Humans; Inhibitory Concentration 50; K562 Cells; Leukemia P388; Mice; Molecular Structure; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 2006 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Topics: Anthracenes; Cell Cycle; Cell Line, Tumor; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Naphthalenes; Nocodazole; Podophyllotoxin; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators | 2007 |
10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Topics: Anthracenes; Binding, Competitive; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; G2 Phase; Humans; Protein Binding; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a new scaffold that provides rapid access to antimicrotubule agents: synthesis and evaluation of antiproliferative activity against select cancer cell lines.
Topics: Acrylamides; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; G2 Phase; Humans; Microtubules; Oxazoles; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators | 2010 |
Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety.
Topics: Anthracenes; Antineoplastic Agents; Benzylidene Compounds; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Protein Multimerization; Protein Structure, Quaternary; Tubulin | 2010 |
Synthesis, antiproliferative activity and inhibition of tubulin polymerization by anthracenone-based oxime derivatives.
Topics: Anthracenes; Antineoplastic Agents; Cell Proliferation; Humans; Inhibitory Concentration 50; K562 Cells; Oximes; Protein Multimerization; Protein Structure, Quaternary; Tubulin | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Topics: Antineoplastic Agents; Biopolymers; Cell Cycle; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Organ Specificity; Oxazines; Phenothiazines; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2011 |
Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization.
Topics: Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Microtubules; Molecular Structure; Schiff Bases; Stereoisomerism; Structure-Activity Relationship; Tubulin | 2011 |
Identification of selective tubulin inhibitors as potential anti-trypanosomal agents.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Proliferation; Cells, Cultured; Fibroblasts; Humans; Models, Molecular; Molecular Sequence Data; Structural Homology, Protein; Sulfonamides; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tubulin; Tubulin Modulators | 2012 |
Design and synthesis of biaryl aryl stilbenes/ethylenes as antimicrotubule agents.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Ethylenes; HeLa Cells; Humans; Models, Molecular; Molecular Structure; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2013 |
A synthetic dolastatin 10 analogue suppresses microtubule dynamics, inhibits cell proliferation, and induces apoptotic cell death.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Proliferation; Colchicine; Depsipeptides; Drug Interactions; Drug Resistance, Neoplasm; GTP Phosphohydrolases; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; Kinetochores; MCF-7 Cells; Microtubules; Mitosis; Protein Multimerization; Protein Structure, Quaternary; Tubulin; Vinblastine | 2013 |
Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Blood-Brain Barrier; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Drug Design; Drug Resistance, Neoplasm; HCT116 Cells; Humans; K562 Cells; MCF-7 Cells; Mice; Mice, Nude; Microtubules; Neoplasms; Polymerization; Sulfonamides; Tubulin; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Novel colchicine-site binders with a cyclohexanedione scaffold identified through a ligand-based virtual screening approach.
Topics: Antineoplastic Agents; Binding Sites; Cell Cycle; Cell Proliferation; Cells, Cultured; Colchicine; Cyclohexanones; Drug Evaluation, Preclinical; Drug Stability; Humans; Neoplasm Invasiveness; Spindle Apparatus; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2014 |
Novel 9'-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluation.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Dose-Response Relationship, Drug; HeLa Cells; Humans; Jurkat Cells; Molecular Docking Simulation; Noscapine; Structure-Activity Relationship | 2014 |
Synthesis and structure-activity relationships of pyridinyl-1H-1,2,3-triazolyldihydroisoxazoles as potent inhibitors of tubulin polymerization.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Isoxazoles; MCF-7 Cells; Models, Molecular; Molecular Structure; Polymerization; Pyridines; Structure-Activity Relationship; Tubulin | 2015 |
Progress Toward the Development of Noscapine and Derivatives as Anticancer Agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Neoplasms; Noscapine | 2015 |
Synthesis and Structure-Activity Relationship Study of 1-Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents.
Topics: | 2015 |
Synthesis and evaluation of benzosuberone embedded with 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole moieties as new potential anti proliferative agents.
Topics: Antineoplastic Agents; Azoles; Cell Line, Tumor; Cell Proliferation; Coumarins; Humans; Molecular Structure; Oxadiazoles; Thiadiazoles; Triazoles | 2015 |
Piperlongumine (piplartine) and analogues: Antiproliferative microtubule-destabilising agents.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Dioxolanes; Female; Humans; MCF-7 Cells; Microtubules; Models, Molecular; Piperidones; Reactive Oxygen Species; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2017 |
N-Heterocyclic (4-Phenylpiperazin-1-yl)methanones Derived from Phenoxazine and Phenothiazine as Highly Potent Inhibitors of Tubulin Polymerization.
Topics: Alkylating Agents; Antineoplastic Agents; Ethylenediamines; G2 Phase Cell Cycle Checkpoints; Humans; K562 Cells; Molecular Docking Simulation; Oxazines; Phenothiazines; Piperazines; Polymerization; Quantitative Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2017 |
Triazolopyridinyl-acrylonitrile derivatives as antimicrotubule agents: Synthesis, in vitro and in silico characterization of antiproliferative activity, inhibition of tubulin polymerization and binding thermodynamics.
Topics: Acrylonitrile; Antineoplastic Agents; Binding Sites; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Polymerization; Pyridines; Structure-Activity Relationship; Thermodynamics; Triazoles; Tubulin; Tubulin Modulators | 2017 |
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Humans; Microtubules; Molecular Structure; Oxazepines; Structure-Activity Relationship | 2019 |
Discover 4β-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Cycle Checkpoints; Colchicine; Drug Design; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; Podophyllotoxin; Tubulin; Tubulin Modulators | 2019 |
Identification of 2,6-Disubstituted 3
Topics: Binding Sites; Cell Differentiation; Cell Proliferation; Drug Design; Dysferlin; Hep G2 Cells; Humans; Imidazoles; Induced Pluripotent Stem Cells; Molecular Docking Simulation; Muscular Dystrophies, Limb-Girdle; Myocytes, Cardiac; MyoD Protein; Protein Structure, Tertiary; Pyridines; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2019 |
Isoquinoline-based biaryls as a robust scaffold for microtubule inhibitors.
Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; HL-60 Cells; Humans; Isoquinolines; Microscopy, Confocal; Microtubules; Molecular Structure; Polymerization; Structure-Activity Relationship; Tubulin Modulators | 2020 |
10-(4-Phenylpiperazine-1-carbonyl)acridin-9(10H)-ones and related compounds: Synthesis, antiproliferative activity and inhibition of tubulin polymerization.
Topics: Acridines; Antineoplastic Agents; Binding Sites; Cell Proliferation; G2 Phase Cell Cycle Checkpoints; Humans; K562 Cells; M Phase Cell Cycle Checkpoints; Molecular Conformation; Molecular Docking Simulation; Piperazines; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2021 |
Design, structure-activity relationship study and biological evaluation of the thieno[3,2-c]isoquinoline scaffold as a potential anti-cancer agent.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship | 2021 |
Antimicrotubule drugs inhibit the polarized insertion of an intracellular glycoprotein pool into the apical membrane of Madin-Darby canine kidney (MDCK) cells.
Topics: Animals; Cell Line; Cell Membrane; Cell Polarity; Colchicine; Cytochalasin D; Dogs; Glycoproteins; Immunohistochemistry; Membrane Fusion; Microtubules; Nocodazole | 1992 |
Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles.
Topics: Actin Cytoskeleton; Animals; Autophagy; Cell Line; Colchicine; Cytochalasin B; Cytochalasin D; Microtubules; Nocodazole; Proteins; Rats; Vacuoles | 1992 |
Disruption of microtubules inhibits the stimulation of tissue plasminogen activator expression and promotes plasminogen activator inhibitor type 1 expression in human endothelial cells.
Topics: Cells, Cultured; Colchicine; Dioxolanes; Endothelium; Gene Expression; Humans; Microtubules; Nocodazole; Phorbol Esters; Plasminogen Inactivators; Tissue Plasminogen Activator; Transcription, Genetic | 1992 |
Functional expression of intrinsic factor-cobalamin receptor by renal proximal tubular epithelial cells.
Topics: Animals; Biological Transport; Cell Line; Colchicine; Dogs; Epithelium; Intrinsic Factor; Kidney Tubules, Proximal; Kinetics; Microvilli; Nocodazole; Opossums; Rats; Receptors, Cell Surface; Vitamin B 12 | 1991 |
Disruption of cytoskeletal structures results in the induction of the urokinase-type plasminogen activator gene expression.
Topics: Actin Cytoskeleton; Animals; Cell Line; Cell Nucleus; Colchicine; Cytochalasin B; Cytoskeleton; Enzyme Induction; Enzyme Precursors; Fluorescent Antibody Technique; Gene Expression; Microtubules; Nocodazole; Plasminogen Activators; Protein Kinases; Restriction Mapping; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Urokinase-Type Plasminogen Activator | 1990 |
Confronting cisternae in cultured mammalian cells: development and prevalence in arrested metaphases.
Topics: Cell Line; Colchicine; Endoplasmic Reticulum; HeLa Cells; Humans; Metaphase; Nocodazole; Vinblastine | 1991 |
Microtubule disruption interferes with the structural and functional integrity of the apical pole in primary cultures of rat hepatocytes.
Topics: Animals; Cell Membrane; Cell Polarity; Colchicine; Fluoresceins; Fluorescent Dyes; Immunoenzyme Techniques; Liver; Membrane Proteins; Microtubules; Nocodazole; Rats | 1991 |
Role of cytoskeleton and surface lectins in Giardia duodenalis attachment to Caco2 cells.
Topics: Animals; Carbohydrates; Cell Adhesion; Cell Line; Colchicine; Cytoskeleton; Giardia; Glucose; Lectins; Mannosephosphates; Microscopy, Electron, Scanning; Nocodazole | 1991 |
Induction of vacuolar apical compartments in the Caco-2 intestinal epithelial cell line.
Topics: Cell Line; Cell Membrane; Colchicine; Epithelium; Humans; Intestines; Microscopy, Electron; Microtubules; Microvilli; Nocodazole; Vacuoles | 1991 |
Microtubule-dissociating drugs and A23187 reveal differences in the inhibition of synaptosomal transmitter release by botulinum neurotoxins types A and B.
Topics: Actin Cytoskeleton; Animals; Botulinum Toxins; Calcimycin; Colchicine; Cyclic AMP; Cyclic GMP; Cytochalasin D; Griseofulvin; Microtubules; Neurotoxins; Nocodazole; Norepinephrine; Rats; Synaptosomes | 1991 |
The murine rac1 gene: cDNA cloning, tissue distribution and regulated expression of rac1 mRNA by disassembly of actin microfilaments.
Topics: Actin Cytoskeleton; Actins; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Colchicine; Cytochalasin B; Cytoskeleton; DNA; Gene Expression Regulation; Gene Library; GTP-Binding Proteins; Mice; Molecular Sequence Data; Nocodazole; Nucleic Acid Conformation; Oligonucleotide Probes; Organ Specificity; rac GTP-Binding Proteins; RNA, Messenger; Swine | 1991 |
Phenotype modulation in primary cultures of rat aortic smooth muscle cells. Effects of drugs that interfere with the functions of the vacuolar system and the cytoskeleton.
Topics: Animals; Aorta; Cell Adhesion; Cell Survival; Cells, Cultured; Chloroquine; Colchicine; Cytochalasins; Cytoskeleton; Male; Microtubules; Monensin; Muscle Development; Muscle, Smooth, Vascular; Nocodazole; Organ Specificity; Rats; Rats, Inbred Strains | 1990 |
Diacylglycerols and PMA are particularly effective stimulators of fluid pinocytosis in human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Chemotaxis, Leukocyte; Colchicine; Diglycerides; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Leukotriene B4; Neutrophils; Nocodazole; Oligopeptides; Pinocytosis; Piperazines; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Effect of antimicrotubule agents on secretion of relaxin by large luteal cells derived from pregnant swine.
Topics: Animals; Colchicine; Corpus Luteum; Female; Hemolytic Plaque Technique; Microtubules; Nocodazole; Pregnancy; Pregnancy, Animal; Relaxin; Vinblastine | 1990 |
Tubular lysosomes and their drug reactivity in cultured resident macrophages and in cell-free medium.
Topics: Ammonium Chloride; Animals; Cell-Free System; Cells, Cultured; Chloroquine; Colchicine; Culture Media; Female; Lysosomes; Macrophages; Mice; Microscopy, Fluorescence; Microtubules; Nocodazole; Tetradecanoylphorbol Acetate | 1990 |
Effects of antimitotic and antimitochondrial agents on the cellular distribution of microtubules and mitochondria.
Topics: Animals; Antineoplastic Agents; Cell Line; Chick Embryo; Colchicine; Fluorescent Antibody Technique; Guinea Pigs; Microtubules; Mitochondria; Mutation; Nocodazole; Podophyllotoxin; Vinblastine | 1990 |
Sperm nuclear transformations consist of enlargement and condensation coordinate with stages of meiotic maturation in fertilized Spisula solidissima oocytes.
Topics: Animals; Antimetabolites; Benzimidazoles; Cell Nucleus; Colchicine; Cytochalasin B; Ethylmaleimide; Female; Fluorescent Dyes; Hydrogen-Ion Concentration; Male; Meiosis; Microscopy, Fluorescence; Microtubules; Mollusca; Nocodazole; Protein Synthesis Inhibitors; Spermatozoa; Staining and Labeling; Temperature; Zygote | 1988 |
Coalignment of microtubules, cytokeratin intermediate filaments, and collagen fibrils in a collagen-secreting cell system.
Topics: Animals; Colchicine; Collagen; Connective Tissue; Cytoskeleton; Goldfish; Immunohistochemistry; Intermediate Filaments; Keratins; Macromolecular Substances; Microscopy, Electron; Microtubules; Nocodazole; Temperature | 1989 |
Sea urchin primary mesenchyme cells: ingression occurs independent of microtubules.
Topics: Alkaloids; Animals; Benzimidazoles; Blastocyst; Colchicine; Culture Techniques; Epithelium; Fluorescent Antibody Technique; Lumicolchicines; Mesoderm; Microtubules; Nocodazole; Paclitaxel; Sea Urchins | 1989 |
Mechanism of agonist-induced down-regulation and subsequent recovery of muscarinic acetylcholine receptors in a clonal neuroblastoma x glioma hybrid cell line.
Topics: Animals; Bacitracin; Benzimidazoles; Carbachol; Cell Membrane; Colchicine; Endocytosis; Glioma; Hybrid Cells; Methylamines; Mice; Microtubules; N-Methylscopolamine; Neuroblastoma; Nocodazole; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Transglutaminases; Tumor Cells, Cultured | 1989 |
In vitro effects of colchicine and nocodazole on ciliogenesis in quail oviduct.
Topics: Animals; Centrioles; Cilia; Colchicine; Female; In Vitro Techniques; Microscopy, Electron; Microtubules; Nocodazole; Oviducts; Quail | 1989 |
Incorporation of tubulin from an evolutionarily diverse source, Physarum polycephalum, into the microtubules of a mammalian cell.
Topics: Animals; Antibodies, Monoclonal; Biological Evolution; Cell Line; Colchicine; Fluorescent Antibody Technique; Immunohistochemistry; Kinetics; Microinjections; Microscopy, Electron; Microtubules; Mitosis; Nocodazole; Physarum; Tubulin | 1989 |
Microtubules are involved in the secretion of proteins at the apical cell surface of the polarized epithelial cell, Madin-Darby canine kidney.
Topics: Animals; Benzimidazoles; Cell Line; Colchicine; Cytochalasin D; Cytochalasins; Dogs; Epithelium; Glycoproteins; Kidney; Kinetics; Microscopy, Electron; Microscopy, Fluorescence; Microtubules; Muramidase; Nocodazole; Proteins | 1989 |
Microtubules and actin microfilaments in the amphibian bladder granular cells.
Topics: Actin Cytoskeleton; Actins; Animals; Cell Membrane; Colchicine; Cytoskeleton; Dioxolanes; Epithelium; Microtubules; Nocodazole; Oxytocin; Rana esculenta; Reference Values; Urinary Bladder | 1989 |
Cyclic activation of histone H1 kinase during sea urchin egg mitotic divisions.
Topics: Ammonium Chloride; Animals; Benzimidazoles; Cell Division; Colchicine; Emetine; Enzyme Activation; Female; Fertilization; Kinetics; Mitosis; Nocodazole; Oocytes; Protamine Kinase; Protein Biosynthesis; Protein Kinases; Quercetin; Sea Urchins | 1988 |
Agonist but not phorbol ester induced desensitization of human lymphocyte prostaglandin receptor is dependent on tubulin polymerization.
Topics: Benzimidazoles; Binding, Competitive; Carcinogens; Colchicine; Cyclic AMP; Dinoprostone; Humans; Leukemia, T-Cell; Nocodazole; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Prostaglandin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured | 1988 |
Regulation of acetylcholinesterase secretion from neuronal cell cultures.--1. Actions of nerve growth factor, cytoskeletal inhibitors and tunicamycin.
Topics: Acetylcholinesterase; Alkaloids; Animals; Benzimidazoles; Cell Line; Colchicine; Cytoskeleton; Glucosamine; Isoenzymes; Nerve Growth Factors; Neurons; Nocodazole; Paclitaxel; Pheochromocytoma; Rats; Tunicamycin | 1985 |
Involvement of microtubules in lipoprotein degradation and utilization for steroidogenesis in cultured rat luteal cells.
Topics: Alkaloids; Animals; Benzimidazoles; Cells, Cultured; Colchicine; Corpus Luteum; Deuterium; Dimethyl Sulfoxide; Female; Humans; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lumicolchicines; Microtubules; Nocodazole; Paclitaxel; Podophyllotoxin; Progesterone; Rats; Time Factors; Vinblastine | 1985 |
Shape changes and chemokinesis of Walker 256 carcinosarcoma cells in response to colchicine, vinblastine, nocodazole and taxol.
Topics: Alkaloids; Animals; Antineoplastic Agents; Benzimidazoles; Carcinoma 256, Walker; Cell Movement; Colchicine; Cytochalasin B; Microtubules; Nocodazole; Paclitaxel; Vinblastine | 1986 |
Microtubules and actin filaments are not critically involved in the biogenesis of epithelial cell surface polarity.
Topics: Actin Cytoskeleton; Actins; Alkaloids; Animals; Benzimidazoles; Cell Compartmentation; Cell Line; Cell Membrane; Colchicine; Cytochalasin D; Cytochalasins; Cytoskeleton; Dogs; Epithelium; Exocytosis; Hemagglutinins, Viral; Kidney; Membrane Glycoproteins; Membrane Proteins; Microscopy, Electron; Microtubules; Nocodazole; Orthomyxoviridae; Paclitaxel; Tubulin; Vesicular stomatitis Indiana virus; Viral Envelope Proteins; Viral Proteins; Virus Replication | 1986 |
Microtubules and the gonadotropic regulation of granulosa cell steroidogenesis.
Topics: 20-alpha-Dihydroprogesterone; Alkaloids; Animals; Benzimidazoles; Cells, Cultured; Colchicine; Female; Follicle Stimulating Hormone; Granulosa Cells; Kinetics; Microtubules; Nocodazole; Paclitaxel; Progesterone; Rats; Rats, Inbred Strains | 1987 |
The cytoskeleton of the cultured human trabecular cell. Characterization and drug responses.
Topics: Alkaloids; Benzimidazoles; Cells, Cultured; Colchicine; Cytochalasin B; Cytoskeleton; Humans; Intermediate Filaments; Microtubules; Nocodazole; Paclitaxel; Trabecular Meshwork; Vimentin | 1988 |
Presence and distribution of vimentin in cynomolgus monkey trabecular cells.
Topics: Alkaloids; Animals; Benzimidazoles; Colchicine; Cytochalasin B; Fluorescent Antibody Technique; Macaca fascicularis; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Nocodazole; Paclitaxel; Tissue Distribution; Trabecular Meshwork; Vimentin | 1988 |
Effect of tubulozole, a new synthetic microtubule inhibitor, on the induction of casein gene expression by prolactin.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Caseins; Cells, Cultured; Colchicine; Dioxolanes; Dioxoles; Female; Fluorescent Antibody Technique; Genes; Mammary Glands, Animal; Microtubules; Nocodazole; Pregnancy; Prolactin; Rabbits; RNA, Messenger; Transcription, Genetic | 1987 |
Colocalisation of acetylated microtubules, glial filaments, and mitochondria in astrocytes in vitro.
Topics: Acetylation; Animals; Antineoplastic Agents; Astrocytes; Benzimidazoles; Cells, Cultured; Colchicine; Cytoskeleton; Fluorescent Antibody Technique; Intermediate Filaments; Microtubules; Mitochondria; Neuroglia; Nocodazole; Rats | 1988 |
The cellular basis of the calcium dependence of GnRH-stimulated gonadotropin release from frog, Rana pipiens, pituitaries.
Topics: Animals; Benzimidazoles; Calcimycin; Calcium; Colchicine; Colforsin; Cytochalasin B; Cytoskeleton; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Nocodazole; Pimozide; Pituitary Gland; Rana pipiens; Secretory Rate; Tetradecanoylphorbol Acetate; Time Factors; Trifluoperazine | 1986 |
"Spiral asters" and cytoplasmic rotation in sea urchin eggs: induction in Strongylocentrotus purpuratus eggs by elevated temperature.
Topics: Animals; Benzimidazoles; Colchicine; Cytochalasins; Cytoplasm; Dyneins; Female; Fluorescent Antibody Technique; Hot Temperature; Microtubules; Nocodazole; Ovum; Rotation; Sea Urchins; Zygote | 1985 |
To what extent is microtubular network involved in antidiuretic response?
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzimidazoles; Colchicine; Diuresis; In Vitro Techniques; Indomethacin; Microtubules; Nocodazole; Oxytocin; Rana esculenta; Urinary Bladder | 1988 |
A transient array of parallel microtubules in frog eggs: potential tracks for a cytoplasmic rotation that specifies the dorso-ventral axis.
Topics: Animals; Benzimidazoles; Cell Membrane; Colchicine; Cytoplasm; Female; Fluorescent Antibody Technique; Histocytochemistry; Immunoenzyme Techniques; Microscopy, Electron; Microtubules; Nocodazole; Ovum; Rana pipiens; Ultraviolet Rays; Xenopus laevis | 1988 |
Intact microtubules are necessary for complete processing, storage and regulated secretion of von Willebrand factor by endothelial cells.
Topics: Benzimidazoles; Cells, Cultured; Colchicine; Endothelium; Female; Fluorescent Antibody Technique; Humans; Lumicolchicines; Microtubules; Nocodazole; Tubulin; Umbilical Veins; von Willebrand Factor | 1987 |
On the role of the nucleus in the structural organization of the cell: dispersion and rearrangement of the Golgi complex in cytoplasts treated with antimicrotubular drugs.
Topics: Animals; Benzimidazoles; Cell Line; Cell Nucleus; Cells, Cultured; Colchicine; Cytochalasin B; Cytoplasm; Fibroblasts; Golgi Apparatus; Horseradish Peroxidase; Immunohistochemistry; Mice; Microtubules; Nocodazole; Wheat Germ Agglutinins | 1988 |
Investigation of endosomal compartments involved in endocytosis and transcytosis of polymeric immunoglobulin A by subcellular fractionation of perfused isolated rat liver.
Topics: Animals; Benzimidazoles; Bile; Cell Compartmentation; Cell Fractionation; Centrifugation, Isopycnic; Colchicine; Endocytosis; Immunoglobulin A; Liver; Microtubules; Nocodazole; Polymers; Rats; Subcellular Fractions | 1988 |
Lymphocyte adherence in multiple sclerosis: role of the cytoskeleton and prostaglandin E.
Topics: Aspirin; Benzimidazoles; Cell Adhesion; Colchicine; Cytoskeleton; Dinoprostone; Humans; Lymphocytes; Multiple Sclerosis; Nocodazole; Prostaglandins E | 1986 |
Microtubule-dependent reticulopodial motility: is there a role for actin?
Topics: Actins; Animals; Benzimidazoles; Colchicine; Cytochalasins; Energy Metabolism; Eukaryota; Fluorescent Antibody Technique; Histocytochemistry; Microtubule-Associated Proteins; Microtubules; Movement; Nocodazole; Potassium Cyanide; Pseudopodia; Salicylamides; Tubulin | 1986 |
Loss of microtubules and alteration of glycoprotein migration in organ cultures of mouse intestine exposed to nocodazole or colchicine.
Topics: Animals; Benzimidazoles; Colchicine; Glycoproteins; Jejunum; Male; Mice; Mice, Inbred ICR; Microscopy, Electron; Microscopy, Fluorescence; Microtubules; Nocodazole; Organ Culture Techniques | 1987 |
A new model of reticulopodial motility and shape: evidence for a microtubule-based motor and an actin skeleton.
Topics: Actins; Benzimidazoles; Biological Transport, Active; Cell Movement; Colchicine; Cold Temperature; Cytochalasin B; Eukaryota; Male; Microtubules; Models, Biological; Nocodazole; Pseudopodia | 1986 |
Cytoplasmic microtubules containing acetylated alpha-tubulin in Chlamydomonas reinhardtii: spatial arrangement and properties.
Topics: Acetylation; Antibodies, Monoclonal; Benzimidazoles; Chlamydomonas; Colchicine; Cold Temperature; Cytoplasm; Flagella; Microtubules; Nocodazole; Tubulin | 1986 |
Calcium and neurulation in mammalian embryos. II. Effects of cytoskeletal inhibitors and calcium antagonists on the neural folds of rat embryos.
Topics: Animals; Benzimidazoles; Calcium; Calcium Channel Blockers; Cells, Cultured; Colchicine; Cytochalasin B; Diazepam; Embryo, Mammalian; Gallic Acid; Microscopy, Electron, Scanning; Nervous System; Nocodazole; Papaverine; Rats | 1986 |
Species-specific differences in toxicity of antimitotic agents toward cultured mammalian cells.
Topics: 4-Butyrolactone; Animals; Benzimidazoles; Biological Transport; Cells, Cultured; Colchicine; Cricetinae; Cricetulus; Griseofulvin; HeLa Cells; Humans; Lignans; Maytansine; Mice; Mitosis; Nocodazole; Podophyllotoxin; Species Specificity; Vinblastine | 1985 |
Evidence that cell surface motility in Allogromia is mediated by cytoplasmic microtubules.
Topics: Animals; Benzimidazoles; Cell Membrane; Colchicine; Cold Temperature; Cytoplasm; Eukaryota; Microscopy, Electron; Microscopy, Phase-Contrast; Microtubules; Nocodazole | 1985 |
The effects of colchicine analogues on the reaction of tubulin with iodo[14C]acetamide and N,N'-ethylenebis(iodoacetamide).
Topics: Alkylation; Animals; Benzaldehydes; Benzimidazoles; Colchicine; Ethylenediamines; Iodoacetamide; Iodoacetates; Mathematics; Nocodazole; Podophyllotoxin; Rabbits; Tropolone; Tubulin | 1985 |
N,N'-Ethylene-bis(iodoacetamide) as a probe for structural and functional characteristics of brine shrimp, squid, and bovine tubulins.
Topics: Alkylation; Animals; Artemia; Benzimidazoles; Cattle; Cell Fractionation; Colchicine; Cross-Linking Reagents; Decapodiformes; Ethylenediamines; Maytansine; Microtubules; Molecular Weight; Nocodazole; Podophyllotoxin; Species Specificity; Tubulin; Vinblastine | 1985 |
Adenosine 3',5'-monophosphate-dependent protein kinase associated with the cytoskeleton of adrenal tumor cells.
Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Benzimidazoles; Calcium; Carrier Proteins; Cell Line; Colchicine; Cytochalasin B; Cytoskeletal Proteins; Cytoskeleton; Intracellular Signaling Peptides and Proteins; Magnesium; Molecular Weight; Nocodazole; Octoxynol; Phosphorylation; Polyethylene Glycols; Protein Kinases; Sodium Dodecyl Sulfate; Solubility; Sonication | 1985 |
Selective retrograde axonal transport of free glycine in identified neurons of Aplysia.
Topics: 2,4-Dinitrophenol; Amino Acids; Animals; Aplysia; Axonal Transport; Benzimidazoles; Colchicine; Dinitrophenols; Ganglia; Glycine; Kinetics; Mercuric Chloride; Nocodazole; Vinblastine | 1984 |
Visualization of assembled and disassembled microtubule protein by double label fluorescence microscopy.
Topics: Animals; Antibodies; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzimidazoles; Carbamates; Colchicine; Female; Granulosa Cells; Microtubules; Nocodazole; Paclitaxel; Rats; Terpenes; Tubulin | 1981 |
Effects of inhibitors of tubulin polymerization on GTP hydrolysis.
Topics: Animals; Benzimidazoles; Brain; Carbamates; Cattle; Colchicine; GTP Phosphohydrolases; Kinetics; Macromolecular Substances; Maytansine; Nocodazole; Oxazines; Phosphoric Monoester Hydrolases; Podophyllotoxin; Solvents; Structure-Activity Relationship; Tubulin; Vinblastine | 1981 |
Unpolymerized tubulin modulates the level of tubulin mRNAs.
Topics: Alkaloids; Animals; Benzimidazoles; Carbamates; Cell Line; Colchicine; Cricetinae; Drosophila; Kinetics; Mice; Nocodazole; Paclitaxel; Polymers; RNA, Messenger; Tubulin; Vinblastine | 1981 |
Interactions of a new antimitotic agent, NSC-181928, with purified tubulin.
Topics: Alkaloids; Animals; Benzimidazoles; Carbamates; Cattle; Colchicine; Guanosine Triphosphate; Hydrolysis; Nocodazole; Paclitaxel; Polymers; Pyrazines; Temperature; Tubulin | 1982 |
Vinblastine inhibits the maturation of the precursor of mitochondrial aspartate aminotransferase. Vincristine and six other cytoskeleton inhibitors do not show this effect.
Topics: Alkaloids; Animals; Aspartate Aminotransferases; Benzimidazoles; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Chick Embryo; Colchicine; Cytochalasin D; Cytochalasins; Enzyme Precursors; Fibroblasts; Kinetics; Mitochondria; Nocodazole; Oxygen Consumption; Paclitaxel; Phalloidine; Podophyllotoxin; Vinblastine | 1983 |
The effects of taxol on the organization of the cytoskeleton in cultured ovarian granulosa cells.
Topics: Alkaloids; Animals; Benzimidazoles; Cells, Cultured; Colchicine; Cytoskeleton; Female; Granulosa Cells; Intermediate Filament Proteins; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel; Rats; Tubulin | 1983 |
The cytoskeletal system of nucleated erythrocytes. III. Marginal band function in mature cells.
Topics: Alkaloids; Animals; Benzimidazoles; Colchicine; Dogfish; Erythrocytes; Microscopy, Electron, Scanning; Microtubules; Nocodazole; Osmolar Concentration; Paclitaxel; Stress, Mechanical; Sucrose | 1984 |
Microtubule-depolymerizing agents inhibit Moloney murine leukaemia virus production.
Topics: Animals; Benzimidazoles; Carbamates; Cell Line; Cell Survival; Colchicine; Mice; Moloney murine leukemia virus; Nocodazole; Protein Biosynthesis; RNA; RNA-Directed DNA Polymerase; Vinblastine; Viral Proteins | 1982 |
Autoregulatory control of expression of alpha and beta tubulin.
Topics: Alkaloids; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzimidazoles; Cell Line; Colchicine; Cricetinae; Cricetulus; Female; Gene Expression Regulation; Homeostasis; Nocodazole; Ovary; Paclitaxel; RNA; Tubulin; Vinblastine | 1983 |
Interplay of cyclic AMP and microtubules in modulating the initiation of DNA synthesis in 3T3 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzimidazoles; Cholera Toxin; Colchicine; Cyclic AMP; DNA Replication; Fibroblasts; Insulin; Mice; Microtubules; Nocodazole | 1983 |
Microtubule-disrupting agents can independently affect the prereplicative period and the entry into S phase stimulated by prostaglandin F2 alpha and fibroblastic growth factor.
Topics: Animals; Benzimidazoles; Colchicine; Demecolcine; Dinoprost; DNA Replication; Fibroblast Growth Factors; Interphase; Mice; Microtubules; Nocodazole; Peptides; Prostaglandins F; Time Factors | 1983 |
Stimulation of the secretion of plasminogen activator from activated murine macrophages by microtubule disrupting agents and deuterium oxide.
Topics: Animals; Benzimidazoles; Carbamates; Colchicine; Deuterium; Deuterium Oxide; Drug Interactions; Fibrin; Macrophages; Male; Mice; Microtubules; Nocodazole; Plasminogen Activators; Stimulation, Chemical | 1980 |
Effects of colchicine, vinblastine and nocodazole on polarity, motility, chemotaxis and cAMP levels of human polymorphonuclear leukocytes.
Topics: Antineoplastic Agents; Benzimidazoles; Cell Aggregation; Cell Movement; Chemotaxis, Leukocyte; Colchicine; Cyclic AMP; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nocodazole; Vinblastine | 1984 |
The relationship between the disassembly of microtubules during G1 and the enhancement of DNA synthesis by colchicine in mouse fibroblasts stimulated with peptide growth hormones.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Brain; Cells, Cultured; Colchicine; DNA Replication; Dogs; Epidermal Growth Factor; Fibroblasts; Fluorescent Antibody Technique; Insulin; Interphase; Kinetics; Mice; Microtubules; Nocodazole; Rats; Swine; Tubulin | 1983 |
Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs.
Topics: Animals; Benzimidazoles; Cell Cycle; Colchicine; Cycloheximide; Egtazic Acid; Female; Fertilization; Growth Substances; Male; Maturation-Promoting Factor; Meiosis; Mitosis; Nocodazole; Oocytes; Ovum; Vinblastine; Xenopus | 1984 |
Brief extraction with detergent induces the appearance of many plasma membrane-associated microtubules in hepatocytic cells.
Topics: Animals; Benzimidazoles; Calcium; Cell Membrane; Colchicine; Detergents; Fluorescent Antibody Technique; Glutaral; Immunoglobulin G; Liver Neoplasms, Experimental; Magnesium; Microscopy, Electron; Microtubules; Nocodazole; Saponins; Surface-Active Agents; Temperature; Tubulin | 1984 |
Nuclear elongation of dissociated newt spermatids in vitro and their nuclear shortening by antimicrotubule agents.
Topics: Animals; Benzimidazoles; Cell Nucleus; Colchicine; Cold Temperature; Demecolcine; Griseofulvin; Kinetics; Male; Microtubules; Nocodazole; Salamandridae; Spermatids; Spermatozoa; Vinblastine | 1984 |
Different effects of tubulin ligands on the intrachain cross-linking of beta 1-tubulin.
Topics: Animals; Benzimidazoles; Brain Chemistry; Cattle; Colchicine; Cross-Linking Reagents; Ethylenediamines; Female; Guanosine Triphosphate; Ligands; Magnesium; Magnesium Chloride; Maytansine; Nocodazole; Podophyllotoxin; Tubulin; Vinblastine | 1984 |
Nocodazole inhibits polyI:C induction of interferon by mouse macrophages.
Topics: Animals; Benzimidazoles; Colchicine; Female; Gene Expression Regulation; Interferon Inducers; Interferon Type I; Macrophages; Mice; Nocodazole; Poly I-C | 1983 |
Neurulation in the Mexican salamander (Ambystoma mexicanum): a drug study and cell shape analysis of the epidermis and the neural plate.
Topics: Ambystoma mexicanum; Animals; Benzimidazoles; Cell Count; Central Nervous System; Colchicine; Cytoskeleton; Epidermis; Microscopy, Electron; Nocodazole | 1983 |
Chromosome motion and the spindle matrix.
Topics: Adenosine Triphosphate; Animals; Benzimidazoles; Cell Movement; Chromosomes; Colchicine; Eukaryota; Microtubules; Models, Biological; Nocodazole; Spindle Apparatus | 1984 |
Dynamics and topographical distribution of surface glycoproteins during myoblast fusion: a resonance energy transfer study.
Topics: Animals; Benzimidazoles; Cell Membrane; Chick Embryo; Colchicine; Concanavalin A; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Membrane Fluidity; Muscles; Nocodazole; Pyrenes; Receptors, Concanavalin A; Spectrometry, Fluorescence; Thiocyanates | 1982 |
Podophyllotoxin-resistant mutants of Chinese hamster ovary cells: cross-resistance studies with various microtubule inhibitors and podophyllotoxin analogues.
Topics: Animals; Benzimidazoles; Cell Line; Cell Survival; Colchicine; Cricetinae; Cricetulus; Drug Resistance; Female; Microtubules; Mutation; Nocodazole; Ovary; Podophyllotoxin; Structure-Activity Relationship; Vinblastine | 1983 |
Biological effects and structure-activity relationships of 1,2-dihydropyrido[3,4-b]pyrazines.
Topics: Animals; Benzimidazoles; Binding, Competitive; Cell Division; Cell Survival; Colchicine; Drug Synergism; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Nocodazole; Pyrazines; Structure-Activity Relationship; Tubulin; Vincristine | 1983 |
A correlation between in vivo and in vitro effects of the microtubule inhibitors colchicine, parbendazole and nocodazole on myxamoebae of Physarum polycephalum.
Topics: Benzimidazoles; Carbamates; Colchicine; In Vitro Techniques; Microscopy, Electron; Microtubules; Nocodazole; Physarum; Tubulin | 1981 |
Effect of tubulin-binding agents on the infiltration of tumour cells into primary hepatocyte cultures.
Topics: Animals; Benzimidazoles; Carbamates; Cell Adhesion; Cell Communication; Cells, Cultured; Colchicine; Liver; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Mice; Microscopy, Electron, Scanning; Nocodazole; Sarcoma, Experimental; Tubulin Modulators; Vinblastine | 1982 |
Cytochalasin separates microtubule disassembly from loss of asymmetric morphology.
Topics: Actins; Animals; Antineoplastic Agents; Benzimidazoles; Carbamates; Cell Line; Colchicine; Cytochalasin B; Cytochalasin D; Cytochalasins; Fluorescent Antibody Technique; Mice; Microscopy, Electron; Microtubules; Neoplasms, Experimental; Neuroblastoma; Nocodazole; Tubulin | 1981 |
Purification of yeast tubulin by self-assembly in vitro.
Topics: Animals; Antifungal Agents; Benzimidazoles; Brain; Carbamates; Cattle; Colchicine; Electrophoresis, Polyacrylamide Gel; Kinetics; Macromolecular Substances; Nocodazole; Saccharomyces; Saccharomyces cerevisiae; Species Specificity; Swine; Tubulin | 1981 |
Structural and functional diversity in the neuronal microtubules of Caenorhabditis elegans.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Caenorhabditis; Carbamates; Cilia; Colchicine; Microscopy, Electron; Microtubules; Neurons; Nocodazole; Podophyllotoxin; Temperature; Vinblastine | 1982 |
Mechanisms of autophagy in resident and thioglycollate-elicited mouse peritoneal macrophages in vivo and in vitro.
Topics: Animals; Ascitic Fluid; Autophagy; Benzimidazoles; Cells, Cultured; Colchicine; Endoplasmic Reticulum; Lysosomes; Macrophage Activation; Macrophages; Mice; Nocodazole; Phagocytosis; Vacuoles | 1982 |
Glucocorticoid hormone renders a rat glioma cell line sensitive to a G1 phase block by microtubule disrupting agents.
Topics: Animals; Benzimidazoles; Cell Cycle; Cell Line; Colchicine; DNA, Neoplasm; Fibroblasts; Glioma; Growth Inhibitors; Hydrocortisone; Interphase; Mice; Microtubules; Mitosis; Neoplasms, Experimental; Nocodazole; Rats | 1982 |
Stimulation of plasminogen activator expression and induction of DNA synthesis by microtubule-disruptive drugs.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Carbamates; Cells, Cultured; Colchicine; Cytochalasin B; DNA Replication; Kinetics; Mice; Microtubules; Nocodazole; Plasminogen Activators; Vinblastine | 1981 |
Effect of microtubule inhibitors on the tubulin system of Dictyostelium discoideum.
Topics: Benzimidazoles; Carbamates; Colchicine; Dictyostelium; Griseofulvin; Herbicides; Microtubules; Nocodazole; Phenylcarbamates; Thiabendazole; Vinblastine | 1982 |
Toxicity of microtubular drugs to leukemic lymphocytes.
Topics: Benzimidazoles; Carbamates; Colchicine; Humans; Leukemia, Lymphoid; Lymphocytes; Maytansine; Microtubules; Nocodazole; Podophyllotoxin; Tropolone; Vinblastine; Vincristine | 1981 |
Nocodazole inhibition of the vasopressin-induced water permeability increase in toad urinary bladder.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Bufonidae; Carbamates; Cell Membrane Permeability; Colchicine; Nocodazole; Urinary Bladder; Vasopressins; Water | 1981 |
Effect of antitubulins on spontaneous and chemotactic migration of neutrophils under agarose.
Topics: Animals; Benzimidazoles; Carbamates; Cell Movement; Chemotaxis, Leukocyte; Colchicine; Female; Hydrogen-Ion Concentration; Mice; Microtubules; Neutrophils; Nocodazole; Osmolar Concentration; Tubulin Modulators; Vinblastine | 1980 |
Effects of nocodazole, a new synthetic microtubule inhibitor, on movement and spreading of mouse peritoneal macrophages.
Topics: Animals; Ascitic Fluid; Benzimidazoles; Carbamates; Cell Movement; Colchicine; Macrophages; Mice; Microtubules; Nocodazole | 1980 |
Regulated and unregulated pathways for MUC2 mucin secretion in human colonic LS180 adenocarcinoma cells are distinct.
Topics: Adenocarcinoma; Biomarkers, Tumor; Calcimycin; Carbachol; Cell Size; Colchicine; Colonic Neoplasms; Cytochalasin D; Cytoplasmic Granules; Golgi Apparatus; Humans; Microscopy, Electron; Monensin; Mucin-2; Mucins; Neoplasm Proteins; Nocodazole; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Expression of the human gene encoding urokinase plasminogen activator receptor is activated by disruption of the cytoskeleton.
Topics: Amanitins; Base Sequence; Cell Size; Cells, Cultured; Colchicine; Cycloheximide; Cytochalasin B; Cytoskeleton; Fibroblasts; Fibrosarcoma; Gene Expression Regulation; Humans; Molecular Sequence Data; Nocodazole; Polymerase Chain Reaction; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Transcriptional Activation; Tumor Cells, Cultured | 1995 |
Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes.
Topics: Actins; Biological Transport; Biomarkers; Colchicine; Cytochalasin D; Dextrans; Endosomes; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Laryngeal Neoplasms; Lysosomes; Microscopy, Video; Microtubules; Nocodazole; Protein Synthesis Inhibitors; Proteins; Ricin; Tumor Cells, Cultured | 1995 |
Microtubule disruption stimulates system A transport in cultured vascular smooth muscle cells.
Topics: Animals; Aorta; beta-Alanine; Biological Transport; Cell Cycle; Cell Division; Cells, Cultured; Colchicine; Culture Media, Serum-Free; Kinetics; Microtubules; Muscle, Smooth, Vascular; Nocodazole; Rats; Vinblastine | 1995 |
Microtubules mediate cellular 25-hydroxyvitamin D3 trafficking and the genomic response to 1,25-dihydroxyvitamin D3 in normal human monocytes.
Topics: Biological Transport; Calcifediol; Calcitriol; Colchicine; Enzyme Induction; Gene Expression; Humans; In Vitro Techniques; Microtubules; Mitochondria; Monocytes; Nocodazole; Receptors, Calcitriol; RNA, Messenger; Steroid Hydroxylases | 1995 |
Prevention of nitric oxide synthase induction in vascular smooth muscle cells by microtubule depolymerizing agents.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Colchicine; Cyclic GMP; Cytoskeleton; Enzyme Induction; In Vitro Techniques; Interleukin-1; Lipopolysaccharides; Microtubules; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroprusside; Nocodazole; omega-N-Methylarginine; Rats; Rats, Wistar | 1993 |
Crystal-induced neutrophil activation. IV. Specific inhibition of tyrosine phosphorylation by colchicine.
Topics: Blood Proteins; Calcium Pyrophosphate; Colchicine; Crystallization; Demecolcine; Humans; In Vitro Techniques; Indomethacin; Kinetics; Neutrophils; Nocodazole; Phenylbutazone; Phosphorylation; Phosphotyrosine; Tyrosine; Uric Acid; Vinblastine | 1993 |
Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Brain; Cell Line; Chlorocebus aethiops; Colchicine; Collagen; Cytochalasin B; Cytochalasin D; Cytoskeleton; Extracellular Matrix; Fibronectins; Gene Expression; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Kidney; Laminin; Microglia; Nocodazole; Peptide Fragments; Polylysine; Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Transfection | 1995 |
Modulation of phenotypic expression of fibroblasts by alteration of the cytoskeleton.
Topics: Animals; Biological Transport; Centrosome; Chick Embryo; Colchicine; Concanavalin A; Cytochalasin B; Cytoskeleton; Endocytosis; Fibroblasts; Glycosaminoglycans; Glycoside Hydrolases; Hyaluronic Acid; Microscopy, Fluorescence; Microtubules; Nocodazole; Phenotype; Protein Biosynthesis; Proteins; Signal Transduction; Tubulin | 1995 |
Volume regulation in leukocytes: requirement for an intact cytoskeleton.
Topics: Actins; Antibodies; Cell Line; Colchicine; Cytochalasins; Cytoskeleton; Flow Cytometry; Integrins; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Nocodazole; Scattering, Radiation | 1995 |
Organization of microtubules in myelinating Schwann cells.
Topics: Aging; Animals; Centrosome; Colchicine; Golgi Apparatus; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Microscopy, Confocal; Microscopy, Electron; Microtubules; Nerve Fibers, Myelinated; Nocodazole; Rats; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve | 1994 |
Antimicrotubule agents induce polyploidization of human leukaemic cell lines with megakaryocytic features.
Topics: Cell Division; Colchicine; Demecolcine; DNA; Flow Cytometry; Humans; Leukemia; Lumicolchicines; Megakaryocytes; Microtubules; Nocodazole; Paclitaxel; Polyploidy; Tumor Cells, Cultured | 1993 |
Gamma-aminobutyric acidA receptor function is inhibited by microtubule depolymerization.
Topics: Animals; Biological Transport; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Chlorides; Colchicine; Convulsants; Dose-Response Relationship, Drug; Flunitrazepam; Histones; Humans; Lumicolchicines; Membranes; Mice; Microtubules; Muscimol; Nocodazole; Paclitaxel; Phosphorylation; Receptors, GABA-A; Vinblastine; Xenopus | 1994 |
Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments.
Topics: Adenine; Biomarkers; Cathepsin D; Colchicine; Fluorescent Antibody Technique; GTP-Binding Proteins; HeLa Cells; Helicobacter pylori; Humans; Immunoblotting; Isoquinolines; Kinetics; Nocodazole; Receptors, Transferrin; Vacuoles | 1994 |
The initiation of neurite outgrowth by sympathetic neurons grown in vitro does not depend on assembly of microtubules.
Topics: Animals; Cells, Cultured; Chick Embryo; Colchicine; Ganglia, Sympathetic; Microscopy, Confocal; Microscopy, Video; Microtubules; Neurites; Neurons; Nocodazole; Paclitaxel; Tubulin | 1994 |
Are microtubules essential for the secretory process in rat parotid gland?
Topics: Animals; Carbachol; Colchicine; Demecolcine; Fluorescent Antibody Technique; Isoproterenol; Kinetics; Male; Microtubules; Nocodazole; Parotid Gland; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley | 1994 |
Forskolin- but not ionomycin-evoked Cl- secretion in colonic epithelia depends on intact microtubules.
Topics: Animals; Chlorides; Colchicine; Colforsin; Colon; Dithiothreitol; Electrophysiology; Fluorescent Antibody Technique; Intestinal Mucosa; Ionomycin; Microtubules; Nocodazole; Rats; Tumor Cells, Cultured | 1994 |
Characterization of 3'-azido-3'-deoxythymidine inhibition of ricin and Pseudomonas exotoxin A toxicity in CHO and Vero cells.
Topics: ADP Ribose Transferases; Animals; Bacterial Toxins; Biological Transport; Brefeldin A; Cell Survival; Cerulenin; CHO Cells; Colchicine; Cricetinae; Cyclopentanes; Dose-Response Relationship, Drug; Exotoxins; Kinetics; Leucine; NAD; Nocodazole; Protein Biosynthesis; Protein Synthesis Inhibitors; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Rabbits; Reticulocytes; Ricin; Vero Cells; Virulence Factors; Zidovudine | 1994 |
Normal cellular processing of the beta-amyloid precursor protein results in the secretion of the amyloid beta peptide and related molecules.
Topics: Amino Acid Sequence; Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Brefeldin A; Cell Line; Colchicine; Cyclopentanes; Golgi Apparatus; Humans; Kidney; Leupeptins; Lysosomes; Molecular Sequence Data; Monensin; Nocodazole; Protein Processing, Post-Translational; Transfection | 1993 |
Microtubule polarity in the peripheral processes of trigeminal ganglion cells: relevance for the retrograde transport of herpes simplex virus.
Topics: Animals; Autoradiography; Cell Polarity; Colchicine; Cornea; Fluorescent Antibody Technique; Microtubules; Neurons; Nocodazole; Rabbits; Simplexvirus; Trigeminal Ganglion; Vinblastine | 1994 |
Possible involvement of microtubule disruption in bipolar budding of a Sendai virus mutant, F1-R, in epithelial MDCK cells.
Topics: Animals; Cell Line; Chick Embryo; Colchicine; Dogs; Glycoproteins; HN Protein; Kidney; Kinetics; Methionine; Microtubules; Mutation; Nocodazole; Parainfluenza Virus 1, Human; Sulfur Radioisotopes; Tubulin; Viral Proteins | 1993 |
Axons regulate the distribution of Schwann cell microtubules.
Topics: Animals; Axons; Cell Differentiation; Cells, Cultured; Centrosome; Colchicine; Ganglia, Spinal; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Fluorescence; Microtubules; Myelin Proteins; Nocodazole; Rats; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve; Wallerian Degeneration | 1996 |
Indications for a threshold of chemically-induced aneuploidy in vitro in human lymphocytes.
Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Cell Division; Cell Survival; Cells, Cultured; Centromere; Colchicine; Flow Cytometry; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Mebendazole; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagens; Nocodazole | 1995 |
Gonococcal opacity protein promotes bacterial entry-associated rearrangements of the epithelial cell actin cytoskeleton.
Topics: Actins; Antigens, Bacterial; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Cell Line; Clathrin; Colchicine; Cytochalasin D; Cytoskeleton; Endocytosis; Epithelium; Escherichia coli; Fluorescent Antibody Technique, Indirect; Humans; Microtubules; Neisseria gonorrhoeae; Nocodazole; Paclitaxel | 1996 |
Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A.
Topics: Alzheimer Disease; Amino Acid Sequence; Antibodies; Autoradiography; Blotting, Western; Cells, Cultured; Colchicine; Electrophoresis, Polyacrylamide Gel; Epitopes; Humans; Methionine; Microtubules; Neurons; Nocodazole; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Protein Phosphatase 2; Serine; Sulfur Radioisotopes; tau Proteins; Teratocarcinoma; Threonine; Tumor Cells, Cultured | 1996 |
Ability of Escherichia coli isolates that cause meningitis in newborns to invade epithelial and endothelial cells.
Topics: Actin Cytoskeleton; Animals; Cell Line; Colchicine; Cytochalasin D; Dogs; Endothelium; Epithelium; Escherichia coli; Escherichia coli Infections; Humans; Infant, Newborn; Meningitis, Bacterial; Microscopy, Electron; Microtubules; Nocodazole; Penicillins; Streptomycin; Virulence | 1996 |
Apoptosis induced by microtubule disrupting drugs in normal murine thymocytes in vitro.
Topics: Animals; Apoptosis; Calcium; Colchicine; Cycloheximide; DNA; Egtazic Acid; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron; Microtubules; Nocodazole; Protein Biosynthesis; T-Lymphocytes; Zinc | 1995 |
Activation of smooth muscle alpha-actin promoter in ras-transformed cells by treatments with antimitotic agents: correlation with stimulation of SRF:SRE mediated gene transcription.
Topics: Actin Cytoskeleton; Actins; Animals; Antineoplastic Agents; Base Sequence; Cell Line; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Colchicine; Consensus Sequence; DNA Primers; DNA-Binding Proteins; Gene Expression Regulation; Genes, ras; Humans; Molecular Sequence Data; Muscle, Smooth; Nocodazole; Oligodeoxyribonucleotides; Paclitaxel; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Thymidine Kinase; Transcription, Genetic; Transfection; Vinblastine; Vincristine; Xenopus laevis | 1995 |
Microtubule-active agents mimic lipopolysaccharides in priming macrophages for enhanced arachidonic acid metabolism.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Colchicine; Female; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Microtubules; Nocodazole; Paclitaxel; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Cytoskeleton-dependent activation of the inducible nitric oxide synthase in cultured aortic smooth muscle cells.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Aorta, Thoracic; Blotting, Western; Cells, Cultured; Colchicine; Cyclic GMP; Cytochalasins; Cytoskeleton; Enzyme Induction; Gout Suppressants; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nocodazole; Paclitaxel; Rats; Rats, Wistar; RNA | 1996 |
Involvement of microtubules in prothoracicotropic hormone-stimulated ecdysteroidogenesis by insect (Manduca sexta) prothoracic glands.
Topics: Actin Cytoskeleton; Animals; Colchicine; Cytochalasin B; Cytochalasin D; Ecdysteroids; Endocrine Glands; In Vitro Techniques; Insect Hormones; Manduca; Microtubules; Nocodazole; Podophyllotoxin; Steroids | 1996 |
Cellular events concurrent with Porphyromonas gingivalis invasion of oral epithelium in vitro.
Topics: Cadaverine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Coated Pits, Cell-Membrane; Colchicine; Cytoskeleton; Endocytosis; Enzyme Inhibitors; Epithelial Cells; Epithelium; Genistein; Humans; Isoflavones; KB Cells; Microtubules; Nasopharynx; Nocodazole; Ouabain; Phosphorylation; Porphyromonas gingivalis; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Receptors, Cell Surface; Signal Transduction; Staurosporine; Tyrosine | 1996 |
Inhibition of LPS-induced tumor necrosis factor-alpha production by colchicine and other microtubule disrupting drugs.
Topics: Animals; Cell Line; Cells, Cultured; Colchicine; Dinoprostone; Extracellular Space; Fibroblasts; Intracellular Fluid; Lipopolysaccharides; Macrophages, Peritoneal; Male; Microtubules; Nocodazole; Rats; Rats, Inbred F344; RNA, Messenger; Tumor Necrosis Factor-alpha; Vinblastine; Vincristine | 1996 |
The effect of microtubule-disrupting drugs on morphology, progesterone and prorenin secretion of bovine cultured ovarian theca cells.
Topics: Animals; Blotting, Western; Cattle; Cells, Cultured; Colchicine; Enzyme Precursors; Female; Immunohistochemistry; Microtubules; Nocodazole; Progesterone; Renin; Theca Cells; Vinblastine | 1996 |
Microtubules and microfilaments participate in the inhibition of synaptosomal noradrenaline release by tetanus toxin.
Topics: Actin Cytoskeleton; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Barium; Cadaverine; Calcium; Cerebral Cortex; Colchicine; Cytochalasin D; Cytoskeleton; Endopeptidases; Energy Metabolism; Enzyme Inhibitors; Gout Suppressants; Membrane Proteins; Microtubules; Nerve Tissue Proteins; Nocodazole; Norepinephrine; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Potassium; R-SNARE Proteins; Rats; Synaptic Vesicles; Synaptosomes; Tetanus Toxin; Transglutaminases | 1997 |
Microtubule depolymerization selectively down-regulates the synthesis of proinflammatory secretory nonpancreatic phospholipase A2.
Topics: Animals; Cells, Cultured; Colchicine; Down-Regulation; Interleukin-1; Microtubules; Nocodazole; Osteoblasts; Paclitaxel; Phospholipases A; Phospholipases A2; Rats; Tumor Necrosis Factor-alpha; Vinblastine | 1997 |
Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes.
Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Chromosomes, Human; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 17; Colchicine; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Lymphocytes; Male; Mebendazole; Methyl Methanesulfonate; Micronucleus Tests; Mutagens; Mutation; Nocodazole; Spindle Apparatus | 1997 |
Invasion of cultured human epithelial cells by Klebsiella pneumoniae isolated from the urinary tract.
Topics: Bacterial Proteins; Cadaverine; Cells, Cultured; Chloramphenicol; Colchicine; Cytochalasin D; Demecolcine; Endocytosis; Epithelial Cells; Epithelium; Humans; Ionophores; Klebsiella pneumoniae; Microtubules; Monensin; Nocodazole; Nucleic Acid Synthesis Inhibitors; Ouabain; Paclitaxel; Protein Synthesis Inhibitors; Salmonella typhi; Urinary Tract; Urinary Tract Infections | 1997 |
Disruption of microtubules reveals two independent apical targeting mechanisms for G-protein-coupled receptors in polarized renal epithelial cells.
Topics: Animals; Cell Polarity; Colchicine; Cytochalasin D; Cytoskeleton; Dogs; Epithelial Cells; Epithelium; GTP-Binding Proteins; Ionophores; Kidney; Microtubules; Models, Biological; Monensin; Nocodazole; Nucleic Acid Synthesis Inhibitors; Receptors, Cell Surface | 1997 |
Microtubule dynamics regulates the level of endothelin-B receptor in rat cultured astrocytes.
Topics: Animals; Astrocytes; Blotting, Northern; Cell Differentiation; Cell Division; Cells, Cultured; Colchicine; DNA; Endothelin-1; Gene Expression; Inositol Phosphates; Microtubules; Nocodazole; Paclitaxel; Rats; Receptor, Endothelin B; Receptors, Endothelin; RNA, Messenger | 1997 |
Dynamics of chromosomes and microtubules visualized by multiple-wavelength fluorescence imaging in living mammalian cells: effects of mitotic inhibitors on cell cycle progression.
Topics: Cell Cycle; Chromosomes; Colchicine; Cytochalasin D; Cytoskeleton; Diketopiperazines; Fluorescent Dyes; HeLa Cells; Humans; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Microtubules; Mitosis; Nocodazole; Piperazines; Rhodamines; Topoisomerase II Inhibitors; Tubulin | 1997 |
The MRD1 (P-glycoprotein) and MRP (P-190) transporters do not play a major role in the intrinsic multiple drug resistance of Jurkat T lymphocytes.
Topics: Antineoplastic Agents; Aphidicolin; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; CD4-Positive T-Lymphocytes; Cell Cycle; Colchicine; Cyclosporine; Drug Resistance, Multiple; Humans; Jurkat Cells; Multidrug Resistance-Associated Proteins; Nocodazole; Polyenes; Sirolimus | 1997 |
Effects of some cytoskeleton inhibitors on ooplasmic segregation in the Nereis virens egg.
Topics: Actins; Animals; Cell Compartmentation; Colchicine; Cytochalasin B; Cytoskeleton; Microtubules; Nocodazole; Ovum; Paclitaxel; Polychaeta | 1997 |
Influence of the cytoskeleton on surfactant protein gene expression in cultured rat alveolar type II cells.
Topics: Animals; Cells, Cultured; Colchicine; Cytochalasin D; Cytoskeleton; Gene Expression Regulation; Kinetics; Male; Nocodazole; Proteolipids; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1998 |
Microtubule coils versus the surface membrane cytoskeleton in maintenance and restoration of platelet discoid shape.
Topics: Actins; Blood Platelets; Cell Membrane; Colchicine; Cold Temperature; Cytochalasin B; Cytoskeleton; Hot Temperature; Humans; Microtubules; Nocodazole; Paclitaxel; Reference Values; Temperature; Vincristine | 1998 |
Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways.
Topics: Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Colchicine; Dose-Response Relationship, Drug; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Microtubules; Mitogen-Activated Protein Kinases; Models, Biological; Nocodazole; Paclitaxel; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-jun; ras Proteins; Regulatory Sequences, Nucleic Acid; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Vinca Alkaloids | 1998 |
Microtubule disruption inhibits AVT-stimulated Cl- secretion but not Na+ reabsorption in A6 cells.
Topics: Animals; Biological Transport; Cell Line; Cell Membrane; Chloride Channels; Chlorides; Colchicine; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Fluorescent Antibody Technique, Indirect; Glyburide; Kidney; Microtubules; Nocodazole; Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium Channels; Vasotocin; Xenopus | 1998 |
The microtubule depolymerizing drugs nocodazole and colchicine inhibit the uptake of Listeria monocytogenes by P388D1 macrophages.
Topics: Actins; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Colchicine; Cytoskeleton; Dendritic Cells; Humans; Leukemia P388; Listeria monocytogenes; Macrophages; Mice; Microtubules; Nocodazole; Paclitaxel; Phagocytosis | 1998 |
Spindle poisons can induce polyploidy by mitotic slippage and micronucleate mononucleates in the cytokinesis-block assay.
Topics: Benzimidazoles; Carbamates; Colchicine; Female; Humans; Leukocyte Count; Leukocytes, Mononuclear; Male; Mebendazole; Methyl Methanesulfonate; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; Nocodazole; Polyploidy; Spindle Apparatus | 1998 |
Role of the cytoskeleton in stimulation of Na+ channels in A6 cells by changes in osmolality.
Topics: Actins; Adenine; Animals; Cell Line; Colchicine; Cytochalasin D; Cytoskeleton; Electric Conductivity; Kidney Tubules, Distal; Microtubules; Nocodazole; Osmolar Concentration; Sodium Channels; Tubulin; Tubulin Modulators; Xenopus laevis | 1998 |
Two distinct pools of synaptic vesicles in single presynaptic boutons in a temperature-sensitive Drosophila mutant, shibire.
Topics: Actins; Animals; Antineoplastic Agents; Colchicine; Cytochalasin D; Drosophila melanogaster; Fluorescent Dyes; Larva; Mutation; Nocodazole; Nucleic Acid Synthesis Inhibitors; Presynaptic Terminals; Pyridinium Compounds; Quaternary Ammonium Compounds; Synaptic Transmission; Synaptic Vesicles; Temperature; Time Factors | 1998 |
Colchicine inhibits GABA(A) receptors independently of microtubule depolymerization.
Topics: Animals; Colchicine; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Microtubules; Nocodazole; Patch-Clamp Techniques; Receptors, GABA-A; Temperature; Time Factors; Vinblastine; Xenopus laevis | 1998 |
Involvement of the cytoskeleton in the movement of cortical granules during oocyte maturation, and cortical granule anchoring in mouse eggs.
Topics: Actins; Animals; Biological Transport; Chromosomes; Colchicine; Cytochalasin D; Cytoskeleton; Mice; Microscopy, Confocal; Movement; Nocodazole; Oocytes; Oogenesis; Ovum | 1998 |
HeLa cells as a model to study the invasiveness and biology of Legionella pneumophila.
Topics: Bacterial Adhesion; Cell Fractionation; Colchicine; Colony Count, Microbial; Cytochalasin D; Cytoskeleton; Galactose; Glucose; HeLa Cells; Humans; Legionella pneumophila; Microscopy, Electron; Nocodazole; Organelles; Virulence | 1998 |
Disruption of endothelial microfilaments selectively reduces the transendothelial migration of monocytes.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cells, Cultured; Coculture Techniques; Colchicine; Culture Media, Conditioned; Cytochalasin B; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Microscopy, Fluorescence; Monocytes; Nocodazole; Paclitaxel; Protein Kinase C; Sulfonamides; Thiazoles; Thiazolidines; Trifluoperazine; Tumor Necrosis Factor-alpha | 1998 |
Stepwise reconstitution of interphase microtubule dynamics in permeabilized cells and comparison to dynamic mechanisms in intact cells.
Topics: 3T3 Cells; Animals; Cell Extracts; Cell Membrane Permeability; Colchicine; Dimerization; Interphase; Mice; Microtubules; Nocodazole; Tubulin; Xenopus | 1998 |
Use of drugs to study role of microtubule assembly dynamics in living cells.
Topics: Alkaloids; Antineoplastic Agents; Biopolymers; Cell Line; Colchicine; Drug Synergism; Microtubules; Molecular Weight; Nocodazole; Paclitaxel; Podophyllotoxin; Tubulin; Vinblastine | 1998 |
Regulation of parathyroid hormone-related protein expression in a canine squamous carcinoma cell line by colchicine.
Topics: Animals; Blotting, Northern; Carcinoma, Squamous Cell; Colchicine; Dogs; Epidermal Growth Factor; Gene Expression Regulation; Luciferases; Lumicolchicines; Neoplasm Proteins; Nocodazole; Paclitaxel; Parathyroid Hormone-Related Protein; Proteins; Radioimmunoassay; RNA, Messenger; Transcription, Genetic; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured; Vinblastine | 1998 |
Podophyllotoxin and nocodazole counter the effect of IKP104 on tubulin decay.
Topics: Alkylation; Animals; Antineoplastic Agents; Binding Sites; Cattle; Colchicine; Iodoacetamide; Nocodazole; Podophyllotoxin; Pyridones; Spectrometry, Fluorescence; Structure-Activity Relationship; Tubulin | 1998 |
Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Colchicine; Egtazic Acid; Enzyme Activation; Humans; Microtubules; Nocodazole; Paclitaxel; Podophyllotoxin; Tumor Cells, Cultured; Vincristine | 1999 |
Involvement of the cytoskeleton in Junin virus multiplication.
Topics: Animals; Antigens, Viral; Calcium Channel Blockers; Chelating Agents; Chlorocebus aethiops; Colchicine; Cytoskeleton; Dimethyl Sulfoxide; Egtazic Acid; Junin virus; Nifedipine; Nocodazole; Vero Cells; Viral Proteins; Virus Replication | 1999 |
Down-regulation of nucleophosmin/B23 mRNA delays the entry of cells into mitosis.
Topics: Antisense Elements (Genetics); Cell Adhesion; Cell Count; Cell Survival; Colchicine; Down-Regulation; HeLa Cells; Humans; Interphase; Metaphase; Mitosis; Mitotic Index; Nocodazole; Nuclear Proteins; Nucleophosmin; RNA, Messenger; Thymidine; Time Factors; Transfection | 1999 |
Alteration of microtubule polymerization modulates arteriolar vasomotor tone.
Topics: Animals; Arterioles; Calcium; Colchicine; Demecolcine; Dose-Response Relationship, Drug; Male; Microtubules; Muscle Tonus; Muscle, Smooth, Vascular; Nocodazole; Polymers; Rats; Rats, Sprague-Dawley; Vasomotor System | 1999 |
Induced differentiation in HT29, a human colon adenocarcinoma cell line.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cadherins; Cell Differentiation; Cell Polarity; Colchicine; Colforsin; Cytochalasin D; Cytoplasm; Fluorescent Antibody Technique; Freeze Fracturing; HT29 Cells; Humans; Microscopy, Electron; Microscopy, Electron, Scanning; Microtubules; Microvilli; Nocodazole; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Tight Junctions | 1999 |
ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation.
Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Carrier Proteins; Caspase 3; Caspase Inhibitors; Caspases; Cerebellum; Colchicine; Cyclosporine; Cysteine Proteinase Inhibitors; Deoxyglucose; Dizocilpine Maleate; Energy Metabolism; Enzyme Activation; Enzyme Inhibitors; Glutathione; Mice; Mice, Inbred BALB C; Microfilament Proteins; Microtubules; Neurons; Neuroprotective Agents; Nitroso Compounds; Nocodazole; Oligopeptides; Paclitaxel; Potassium; Protein Biosynthesis; S-Nitrosoglutathione; Tacrolimus; Verapamil | 1999 |
Intracellular growth in Acanthamoeba castellanii affects monocyte entry mechanisms and enhances virulence of Legionella pneumophila.
Topics: Acanthamoeba; Animals; Cell Line; Colchicine; Complement System Proteins; Cytochalasin D; Humans; Intracellular Fluid; Legionella pneumophila; Mice; Mice, Inbred C57BL; Monocytes; Nocodazole; Phagocytosis; Virulence | 1999 |
Different adhesion properties of highly and poorly metastatic HT-29 colon carcinoma cells with extracellular matrix components: role of integrin expression and cytoskeletal components.
Topics: Acrylamide; Antibodies; Cell Adhesion; Colchicine; Colonic Neoplasms; Cycloheximide; Cytochalasin D; Cytoskeleton; Extracellular Matrix; Humans; Integrins; Neoplasm Metastasis; Nocodazole; Tumor Cells, Cultured | 1999 |
Characteristics of a membrane reservoir buffering membrane tension.
Topics: 3T3 Cells; Actins; Animals; Cell Membrane; Cell Size; Chick Embryo; Colchicine; Cytochalasins; Cytoskeleton; Fibroblasts; Hypotonic Solutions; Kinetics; Lasers; Mice; Microspheres; Nocodazole; Osmolar Concentration; Osmotic Pressure; Physical Stimulation | 1999 |
Microtubules regulate local Ca2+ spiking in secretory epithelial cells.
Topics: Animals; Calcium; Cells, Cultured; Colchicine; Dose-Response Relationship, Drug; Epithelial Cells; Mice; Microtubules; Nocodazole; Paclitaxel; Pancreas | 2000 |
Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways.
Topics: 2-Methoxyestradiol; Breast; Cell Line; Colchicine; Cyclooxygenase 2; Epithelial Cells; Estradiol; Female; Humans; Isoenzymes; Kinetics; Membrane Proteins; Microtubules; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nocodazole; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Prostaglandin-Endoperoxide Synthases; Transcription, Genetic; Vinblastine; Vincristine | 2000 |
Modulation of paclitaxel resistance by annexin IV in human cancer cell lines.
Topics: Annexin A4; Blotting, Western; Colchicine; Colonic Neoplasms; DNA, Complementary; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Lung Neoplasms; Neoplasm Proteins; Nocodazole; Paclitaxel; Recombinant Fusion Proteins; Transfection; Tubulin Modulators; Tumor Cells, Cultured | 2000 |
Influence of microtubules on vascular smooth muscle contraction.
Topics: Animals; Cells, Cultured; Colchicine; Dimerization; Dimethyl Sulfoxide; Male; Microtubules; Muscle Contraction; Muscle, Smooth, Vascular; Nocodazole; Rats; Rats, Sprague-Dawley | 2000 |
Role of microtubules in LPS-induced macrophage inflammatory protein-2 production from rat pneumocytes.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Brefeldin A; Bronchi; Cells, Cultured; Chemokine CXCL2; Chemokines; Colchicine; Endoplasmic Reticulum; Gene Expression; Golgi Apparatus; Lipopolysaccharides; Male; Microtubules; Nocodazole; Paclitaxel; Protein Synthesis Inhibitors; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; RNA, Messenger | 2000 |
The role of GTP Binding and microtubule-associated proteins in the inhibition of microtubule assembly by carbendazim.
Topics: Animals; Benzimidazoles; Brain; Carbamates; Cell Fractionation; Colchicine; Guanosine Triphosphate; Male; Microtubule-Associated Proteins; Microtubules; Nocodazole; Rats; Rats, Sprague-Dawley; Testis; Tubulin | 2001 |
Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells.
Topics: Animals; Bacterial Proteins; Cell Cycle; Cell Line; Colchicine; DNA Replication; DNA, Mitochondrial; Electron Transport Complex IV; G2 Phase; Genes, Reporter; Humans; Intracellular Membranes; Kinetics; Luminescent Proteins; Mammals; Membrane Potentials; Microtubules; Mitochondria; Mitochondria, Liver; Mitosis; Nocodazole; Osteosarcoma; Paclitaxel; Rats; Transfection | 2001 |
Endothelial microtubule disruption blocks flow-dependent dilation of arterioles.
Topics: Animals; Antineoplastic Agents; Arterioles; Colchicine; Endothelium, Vascular; In Vitro Techniques; Male; Microtubules; Muscle, Skeletal; Nocodazole; Rats; Rats, Wistar; Regional Blood Flow; Stress, Mechanical; Vasodilation | 2001 |
Determination of the net exchange rate of tubulin dimer in steady-state microtubules by fluorescence correlation spectroscopy.
Topics: Animals; Colchicine; Dimerization; Fluorescent Dyes; Microtubules; Nocodazole; Paclitaxel; Rhodamines; Spectrometry, Fluorescence; Tubulin; Vincristine | 2001 |
Hypertonic activation of the renal betaine/GABA transporter is microtubule dependent.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Cell Line; Cell Membrane; Colchicine; Cycloheximide; Dogs; Dose-Response Relationship, Drug; Epithelial Cells; GABA Plasma Membrane Transport Proteins; Hypertonic Solutions; Isotonic Solutions; Kidney Tubules, Collecting; Kidney Tubules, Distal; Membrane Proteins; Membrane Transport Proteins; Mice; Microscopy, Confocal; Microtubules; Nocodazole; Organic Anion Transporters; Protein Synthesis Inhibitors; Up-Regulation; Water-Electrolyte Balance | 2001 |
Regulation of PGE(2) and PGI(2) release from human umbilical vein endothelial cells by actin cytoskeleton.
Topics: Actins; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Survival; Cells, Cultured; Colchicine; Cytochalasin D; Cytoskeleton; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Kinetics; Marine Toxins; Microtubules; Nocodazole; Thiazoles; Thiazolidines; Umbilical Veins | 2001 |
Microtubule disruption modulates the Rho-kinase pathway in vascular smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Antineoplastic Agents; Aorta; Azepines; Calcium; Colchicine; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Male; Microtubules; Muscle Contraction; Muscle, Smooth, Vascular; Nocodazole; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstrictor Agents | 2001 |
Effects of silver ion (Ag+) on a cellular shape change in the absence of microtubules in fertilized eggs of Ilyanassa obsoleta.
Topics: Animals; Cell Size; Cleavage Stage, Ovum; Colchicine; Cytoskeleton; Embryo, Nonmammalian; Ions; Microtubules; Nocodazole; Silver; Snails | 1998 |
The microtubule cytoskeleton participates in control of beta2 integrin avidity.
Topics: Animals; Antineoplastic Agents; CD18 Antigens; Cell Adhesion; Cell Aggregation; Cell Line; Cell Line, Transformed; Colchicine; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Gout Suppressants; Humans; Integrins; Macrophages; Mice; Microscopy, Video; Microtubules; Models, Statistical; Nocodazole; Paclitaxel; Paxillin; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine | 2001 |
Gap junctions assemble in the presence of cytoskeletal inhibitors, but enhanced assembly requires microtubules.
Topics: Actins; Animals; Cell Aggregation; Cell Line; Colchicine; Connexin 43; Cytochalasin B; Cytoskeleton; Dogs; Freeze Fracturing; Gap Junctions; Green Fluorescent Proteins; Liver Neoplasms, Experimental; Luminescent Proteins; Microtubules; Nocodazole; Rats; Tumor Cells, Cultured | 2002 |
G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells.
Topics: Breast Neoplasms; Colchicine; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Female; G1 Phase; G2 Phase; Humans; Microtubules; Nocodazole; Paclitaxel; Tumor Cells, Cultured; Vincristine | 2002 |
Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics.
Topics: Adenoviruses, Human; Apoptosis; Biological Transport; Cell Nucleus; Colchicine; Doxorubicin; Epothilones; HeLa Cells; Humans; Macrolides; Microtubules; Nocodazole; Nuclear Proteins; Paclitaxel; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Transcriptional Activation; Tubulin; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vincristine | 2002 |
Ultrafine particles cause cytoskeletal dysfunctions in macrophages.
Topics: Air Pollutants; Animals; Apoptosis; Carbon; Cell Division; Colchicine; Cytochalasin D; Cytoskeleton; Dogs; Flow Cytometry; Macrophages, Alveolar; Mice; Microspheres; Necrosis; Nocodazole; Particle Size; Phagocytosis; Surface Properties | 2002 |
Characterization of nuclear betaII-tubulin in tumor cells: a possible novel target for taxol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Nucleolus; Cell Nucleus; Colchicine; Dimerization; Dose-Response Relationship, Drug; Female; Fluorescent Dyes; Humans; Neoplasms; Nocodazole; Nucleolin; Paclitaxel; Phosphoproteins; Protein Isoforms; Rats; RNA-Binding Proteins; Tubulin; Tumor Cells, Cultured | 2002 |
Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Arsenates; Blotting, Western; Colchicine; Colonic Neoplasms; Cytosol; DNA Fragmentation; Enzyme Activation; Flow Cytometry; Genes, p53; Gout Suppressants; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; Mitogen-Activated Protein Kinases; Nocodazole; Oligonucleotides; Phosphorylation; Plasmids; Protein Structure, Tertiary; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vinblastine | 2002 |
Presenilin-binding protein forms aggresomes in monkey kidney COS-7 cells.
Topics: Animals; Carrier Proteins; Colchicine; COS Cells; Cysteine Endopeptidases; Gene Expression; Haplorhini; Inclusion Bodies; Intermediate Filaments; Kidney; Macromolecular Substances; Membrane Proteins; Microtubules; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Nocodazole; Presenilin-1; Proteasome Endopeptidase Complex; Rats; Transfection; Ubiquitin; Vimentin | 2002 |
Microtubule depolymerization facilitates contraction of rat aorta via activation of Rho-kinase.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Colchicine; Enzyme Activation; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Microtubules; Muscle Contraction; Muscle, Smooth; Nocodazole; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; rho-Associated Kinases | 2002 |
Inhibition of in vitro attachment of Giardia trophozoites by mucin.
Topics: Animals; Antiprotozoal Agents; Cattle; Cell Adhesion; Colchicine; Cytochalasin B; Enzyme-Linked Immunosorbent Assay; Gastric Mucins; Giardia lamblia; Giardiasis; Intestinal Mucosa; Microscopy, Electron, Scanning; Nocodazole; Swine | 2002 |
Microtubules are required for cytokeratin aggresome (Mallory body) formation in hepatocytes: an in vitro study.
Topics: Animals; Antibodies; Cells, Cultured; Colchicine; Dihydropyridines; Hepatocytes; Inclusion Bodies; Keratins; Liver; Lumicolchicines; Male; Mice; Mice, Inbred C3H; Microtubules; Nocodazole; Ubiquitin | 2003 |
Uptake of histamine by mouse peritoneal macrophages and a macrophage cell line, RAW264.7.
Topics: Animals; Antineoplastic Agents; Cell Line; Colchicine; Cytoskeleton; Diet; Dose-Response Relationship, Drug; Female; Histamine; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nocodazole; Spleen | 2003 |
Microtubule network facilitates nuclear targeting of human cytomegalovirus capsid.
Topics: Biological Transport; Caco-2 Cells; Capsid; Cell Line; Cell Nucleus; Colchicine; Cytochalasin B; Cytomegalovirus; Cytoplasm; Fluorescent Antibody Technique; Gene Expression Regulation, Viral; Humans; Immediate-Early Proteins; Microscopy, Electron; Microtubules; Nocodazole; Viral Proteins | 2003 |
Role of microfilaments and microtubules in the invasion of INT-407 cells by Campylobacter jejuni.
Topics: Actin Cytoskeleton; Actins; Biopolymers; Campylobacter jejuni; Cells, Cultured; Colchicine; Cytochalasin D; Cytoskeleton; Dose-Response Relationship, Drug; Endocytosis; Epithelial Cells; Humans; Intestines; Microscopy, Fluorescence; Microtubules; Nocodazole; Species Specificity; Tubulin; Virulence | 2003 |
Modulation of the expression of connective tissue growth factor by alterations of the cytoskeleton.
Topics: Actins; Amides; Bacterial Proteins; Bacterial Toxins; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Colchicine; Connective Tissue Growth Factor; Cytochalasin D; Cytoskeleton; Fibroblasts; Gene Expression Regulation; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Nocodazole; Paclitaxel; Pyridines; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Stress, Mechanical; Thiazoles; Thiazolidines | 2003 |
The effect of drugs on cell structure of Tritrichomonas foetus.
Topics: Animals; Cell Cycle; Colchicine; Flow Cytometry; Microscopy, Electron; Microtubules; Nocodazole; Paclitaxel; Protozoan Infections; Tritrichomonas foetus | 2004 |
Determination of four sequential stages during microautophagy in vitro.
Topics: Autophagy; Cell-Free System; Colchicine; Cytosol; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Intracellular Membranes; Kinetics; Luciferases; Lysosomes; Microscopy, Electron; Nocodazole; Saccharomyces cerevisiae; Temperature; Time Factors; Vacuoles | 2004 |
Glycogen synthase kinase-3 regulates cytoskeleton and translocation of Rac1 in long cellular extensions of human keratinocytes.
Topics: Aminophenols; Cells, Cultured; Colchicine; Cytochalasin D; Cytoskeleton; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Humans; Keratinocytes; Lithium Chloride; Maleimides; Nocodazole; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Pseudopodia; rac1 GTP-Binding Protein; Staurosporine | 2004 |
Regulation of Ras-MAPK pathway mitogenic activity by restricting nuclear entry of activated MAPK in endoderm differentiation of embryonic carcinoma and stem cells.
Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Carcinoma, Embryonal; Cell Differentiation; Cell Line; Cell Nucleus; Colchicine; Cytochalasin D; Cytoskeleton; Endoderm; Enzyme Activation; Fatty Acids, Unsaturated; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Nocodazole; Nucleic Acid Synthesis Inhibitors; Proto-Oncogene Proteins c-fos; ras Proteins; Stem Cells; Subcellular Fractions; Tretinoin | 2004 |
Localization of microtubules during macronuclear division in Tetrahymena and possible involvement of macronuclear microtubules in 'amitotic' chromatin distribution.
Topics: Animals; Benomyl; Cell Division; Cell Nucleus; Chromatin; Colchicine; Cytoplasm; DNA, Protozoan; Interphase; Micronucleus, Germline; Microtubules; Mitosis; Models, Biological; Nocodazole; Paclitaxel; Tetrahymena | 1999 |
Unloaded shortening velocity in single permeabilized vascular smooth muscle cells is independent of microtubule status.
Topics: Actins; Animals; Calcium; Cell Adhesion; Cell Membrane Permeability; Cell Shape; Colchicine; Immunohistochemistry; Kinetics; Microscopy, Fluorescence; Microtubules; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nocodazole; Paclitaxel; Rabbits | 2004 |
Disruption of microtubular network attenuates histamine-induced dilation in rat mesenteric vessels.
Topics: Animals; Antineoplastic Agents; Colchicine; Dose-Response Relationship, Drug; Endothelium, Vascular; Gout Suppressants; Histamine; Male; Mesenteric Arteries; Microtubules; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nocodazole; Organ Culture Techniques; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2005 |
Role of microtubules in ischemic preconditioning against myocardial infarction.
Topics: Animals; Biological Transport; Colchicine; Enzyme Activation; Enzyme Inhibitors; Ischemic Preconditioning, Myocardial; Male; Microtubules; Myocardial Infarction; Myocardium; Nocodazole; p38 Mitogen-Activated Protein Kinases; Perfusion; Protein Kinase C; Rabbits | 2004 |
Disruption of microtubules leads to glucocorticoid receptor degradation in HeLa cell line.
Topics: Animals; Anthracenes; Chlorocebus aethiops; Colchicine; COS Cells; Cysteine Proteinase Inhibitors; Cytosol; Dexamethasone; Enzyme Inhibitors; HeLa Cells; Humans; Intranuclear Space; JNK Mitogen-Activated Protein Kinases; Leupeptins; Microtubules; Mutation; NF-kappa B; Nocodazole; Proteasome Endopeptidase Complex; Protein Transport; Receptors, Glucocorticoid; Transfection; Ubiquitin; Vincristine | 2005 |
Akt activation is necessary for growth factor-induced trafficking of functional K(Ca) channels in developing parasympathetic neurons.
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cells, Cultured; Chick Embryo; Colchicine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Ganglia, Parasympathetic; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Growth Substances; Membrane Potentials; Neuregulin-1; Neurons; Nocodazole; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Time Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Changes in physicochemical properties of microtubules lead to the formation of a single spherical structure of mitochondrial assembly enveloping nuclear chromatins.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Nucleus; Chromatin; Colchicine; Flow Cytometry; Humans; Immunohistochemistry; Microscopy, Confocal; Microscopy, Electron, Transmission; Microtubules; Mitochondria; Nocodazole; Paclitaxel | 2004 |
N-formyl-Met-Leu-Phe-induced oxidative burst in DMSO-differentiated HL-60 cells requires active Hsp90, but not intact microtubules.
Topics: Cell Differentiation; Colchicine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; Microtubules; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nocodazole; Paclitaxel; Respiratory Burst | 2004 |
Giardia lamblia: evaluation of the in vitro effects of nocodazole and colchicine on trophozoites.
Topics: Animals; Antiprotozoal Agents; Cell Adhesion; Cell Cycle; Colchicine; Cytoskeleton; Giardia lamblia; Immunohistochemistry; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Microtubules; Movement; Nocodazole | 2005 |
Microtubule disruption suppresses allergic response through the inhibition of calcium influx in the mast cell degranulation pathway.
Topics: Animals; Calcium Signaling; Cell Degranulation; Cell Line; Colchicine; Endoplasmic Reticulum; In Vitro Techniques; Male; Mast Cells; Mice; Mice, Inbred C57BL; Microtubules; Nocodazole; Passive Cutaneous Anaphylaxis; Rats; Rats, Sprague-Dawley | 2005 |
Growth factors mobilize multiple pools of KCa channels in developing parasympathetic neurons: role of ADP-ribosylation factors and related proteins.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; Biological Transport; Boron Compounds; Brefeldin A; Cells, Cultured; Chick Embryo; Colchicine; Drug Interactions; Endoplasmic Reticulum; Ganglia, Parasympathetic; Golgi Apparatus; Green Fluorescent Proteins; Membrane Potentials; Mutagenesis; Neuregulin-1; Neurons; Nocodazole; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Protein Synthesis Inhibitors; Time Factors; Transfection | 2005 |
Selective vulnerability of dopaminergic neurons to microtubule depolymerization.
Topics: Cell Death; Colchicine; Cytosol; Dopamine; Humans; Microtubules; Nerve Degeneration; Nocodazole; Oxidative Stress; Paclitaxel; Parkinson Disease; Polymers; Receptors, Dopamine; Rotenone; Substantia Nigra; Uncoupling Agents | 2005 |
A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach.
Topics: 2-Methoxyestradiol; 4-Butyrolactone; Aminophenols; Binding Sites; Chalcone; Colchicine; Cyclopropanes; Estradiol; Indans; Lignans; Models, Molecular; Molecular Structure; Nocodazole; Podophyllotoxin; Protein Binding; Stilbenes; Structure-Activity Relationship; Sulfonamides; Thiazoles; Tubulin; Tubulin Modulators | 2005 |
Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter.
Topics: alpha-Synuclein; Animals; Cell Line; Cells, Cultured; Colchicine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Kinetics; Male; Mice; Microtubules; Nocodazole; Rats; Substantia Nigra; Transfection; Tubulin; Vinblastine | 2005 |
Cell adhesion regulates Ser/Thr phosphorylation and proteasomal degradation of HEF1.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Cell Adhesion; Cell Line; Colchicine; Cytochalasin D; Enzyme Inhibitors; Humans; Intermediate Filaments; Marine Toxins; Microtubules; Nocodazole; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Isoforms; Protein Phosphatase 2; Pyrans; Serine; Signal Transduction; Spiro Compounds; Threonine; Tubulin Modulators | 2006 |
Microtubular integrity differentially modifies the saturated and unsaturated fatty acid metabolism in cultured Hep G2 human hepatoma cells.
Topics: Cell Line, Tumor; Cell Survival; Colchicine; Cytochalasin B; Cytoskeleton; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Fatty Acid Desaturases; Fatty Acids; Fatty Acids, Unsaturated; Humans; Microtubules; Nocodazole; Tubulin; Vinblastine | 2005 |
Neuronal BC1 RNA: microtubule-dependent dendritic delivery.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cells, Cultured; Colchicine; Cytochalasin D; Dendrites; Hippocampus; Microtubules; Neurons; Nocodazole; Nucleic Acid Synthesis Inhibitors; Rats; RNA, Small Cytoplasmic; Sympathetic Nervous System | 2006 |
Involvement of cytoskeleton in AhR-dependent CYP1A1 expression.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Cell Survival; Cells, Cultured; Colchicine; Cytochrome P-450 CYP1A1; Cytoskeleton; Flow Cytometry; G2 Phase; Hepatocytes; Humans; Liver Neoplasms; Microtubules; Nocodazole; Polychlorinated Dibenzodioxins; Rats; Receptors, Aryl Hydrocarbon; RNA, Messenger; Teratogens | 2006 |
Axonal transport of human immunodeficiency virus type 1 envelope protein glycoprotein 120 is found in association with neuronal apoptosis.
Topics: Animals; Animals, Newborn; Anti-HIV Agents; Apoptosis; Axons; Benzylamines; Caspase 3; Caspases; Cells, Cultured; Colchicine; Corpus Striatum; Cyclams; Glial Fibrillary Acidic Protein; Heterocyclic Compounds; HIV Envelope Protein gp120; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Immunoelectron; Microtubule-Associated Proteins; Neurons; Nocodazole; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; Time Factors; Tyrosine 3-Monooxygenase | 2006 |
Microtubules regulate expression of ICAM-1 in epidermoid cells (KB cells).
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Northern; Colchicine; Humans; Immunoblotting; Integrins; Intercellular Adhesion Molecule-1; Interferon-gamma; KB Cells; Microtubules; Nocodazole; Receptors, Cell Surface; RNA, Messenger; Vinblastine | 2006 |
Formation of filopodia in earthworm (Lumbricus terrestris) coelomocytes in response to osmotic stress.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Colchicine; Cytochalasin D; Nocodazole; Oligochaeta; Osmolar Concentration; Pseudopodia; Sodium Chloride; Thiazolidines; Time Factors; Tubulin; Water | 2007 |
Microtubule-mediated and microtubule-independent transport of adenovirus type 5 in HEK293 cells.
Topics: Adenoviridae; Antineoplastic Agents; Biological Transport; Colchicine; Genome, Viral; Golgi Apparatus; HeLa Cells; Humans; Microtubule-Organizing Center; Microtubules; Nocodazole; Nuclear Pore; Time Factors; Tubulin Modulators; Virion; Virus Replication | 2007 |
Tight junction targeting and intracellular trafficking of occludin in polarized epithelial cells.
Topics: Animals; Caco-2 Cells; Calcium; Cell Polarity; Colchicine; Cytochalasin D; Cytoplasm; Cytoskeleton; Dogs; Endoplasmic Reticulum; Epithelial Cells; Green Fluorescent Proteins; Humans; Intestinal Mucosa; Intestines; Kidney; Magnesium; Membrane Proteins; Microscopy, Confocal; Nocodazole; Occludin; Peptide Fragments; Peptide Mapping; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; Temperature; Tight Junctions; Transfection; Transport Vesicles; Tubulin Modulators | 2007 |
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants.
Topics: Adaptor Proteins, Signal Transducing; CARD Signaling Adaptor Proteins; Caspase 1; Cell Line; Colchicine; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Familial Mediterranean Fever; Genetic Vectors; Genotype; Humans; Immunity, Innate; Interleukin-1beta; Monocytes; Multiprotein Complexes; Mutation; Nocodazole; Phenotype; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrin; Recombinant Fusion Proteins; Retroviridae; Transfection; Tubulin Modulators | 2007 |
Microtubule-targeted drugs inhibit VEGF receptor-2 expression by both transcriptional and post-transcriptional mechanisms.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Colchicine; Endothelium, Vascular; Humans; Microtubules; Nocodazole; RNA Processing, Post-Transcriptional; RNA, Messenger; Sp1 Transcription Factor; Thiazolidines; Transcription, Genetic; Tubulin Modulators; Vascular Endothelial Growth Factor Receptor-2; Vinblastine | 2008 |
Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation.
Topics: Adult; B-Lymphocytes; Cell Line; Colchicine; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Humans; Insecticides; Male; Mesencephalon; Middle Aged; Mutation; Neurons; Nocodazole; Parkinson Disease; Protein Structure, Tertiary; Rotenone; Tubulin Modulators; Ubiquitin-Protein Ligases | 2009 |
AcMNPV EXON0 (AC141) which is required for the efficient egress of budded virus nucleocapsids interacts with beta-tubulin.
Topics: Animals; Colchicine; Immunoprecipitation; Microtubules; Nocodazole; Nucleocapsid; Nucleopolyhedroviruses; Open Reading Frames; Spodoptera; Tubulin; Tubulin Modulators; Viral Proteins | 2009 |
Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption.
Topics: Animals; Colchicine; Connective Tissue Growth Factor; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; MAP Kinase Signaling System; Mice; Microtubules; Mitogen-Activated Protein Kinase Kinases; Nocodazole; Phosphorylation; Plasminogen Activator Inhibitor 1; Proto-Oncogene Proteins pp60(c-src); Reactive Oxygen Species; rho-Associated Kinases; rhoA GTP-Binding Protein; Smad Proteins; Transcriptional Activation; Tubulin Modulators | 2009 |
Cytoskeletal reorganisation, 1alpha,25-dihydroxy vitamin D3 and human MG63 osteoblast maturation.
Topics: Calcitriol; Cell Line; Colchicine; Dipeptides; Focal Adhesion Kinase 1; Humans; Lysophospholipids; Mitogen-Activated Protein Kinase Kinases; Morpholines; Nocodazole; Osteoblasts; Osteocalcin; raf Kinases; ras Proteins; Smad2 Protein; Smad3 Protein; Stress Fibers; Transcription Factor AP-1; Tubulin Modulators | 2009 |
The initial segment of the rat epididymis is able to uptake immature germ cells shed by testicular damage.
Topics: Animals; Colchicine; Epididymis; Germ Cells; Male; Microscopy, Electron, Transmission; Nocodazole; Rats; Rats, Wistar; Seminiferous Tubules | 2011 |
Disruption of microtubules sensitizes the DNA damage-induced apoptosis through inhibiting nuclear factor κB (NF-κB) DNA-binding activity.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Caspases; Cell Line; Colchicine; DNA; DNA Damage; Doxorubicin; Humans; Mice; Microtubules; Neoplasms; NF-kappa B; Nocodazole; Protein Binding; Signal Transduction; Tubulin Modulators; Vinblastine | 2010 |
Free tubulin modulates mitochondrial membrane potential in cancer cells.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Membrane; Colchicine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic CMP; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Liver Neoplasms; Male; Membrane Potential, Mitochondrial; Membrane Potentials; Microtubules; Mitochondria, Liver; Neoplasms; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Rhodamines; Rotenone; Tubulin | 2010 |
UA62784 Is a cytotoxic inhibitor of microtubules, not CENP-E.
Topics: Apoptosis; Binding Sites; Chromosomal Proteins, Non-Histone; Colchicine; Dimerization; HeLa Cells; Humans; Microtubules; Mitosis; Nocodazole; Oxazoles; Spindle Apparatus; Tubulin; Tubulin Modulators; Vinblastine; Xanthones | 2011 |
Interfacial behavior of immortalized hypothalamic mouse neurons detected by acoustic wave propagation.
Topics: Animals; Cell Adhesion; Cells, Cultured; Colchicine; Cytochalasin B; Cytochalasin D; Cytoskeleton; Hypothalamus; Mice; Neurons; Nocodazole; Phalloidine; Sound; Surface Properties | 2011 |
Molecular cytogenetic evaluation of the mechanism of genotoxic potential of amsacrine and nocodazole in mouse bone marrow cells.
Topics: Amsacrine; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow Cells; Centromere; Colchicine; Cytogenetics; DNA Probes; Dose-Response Relationship, Drug; Erythrocytes; In Situ Hybridization; In Vitro Techniques; Male; Mice; Micronucleus Tests; Mitomycin; Mutagens; Nocodazole | 2013 |
Resistin in gingival crevicular fluid and induction of resistin release by Porphyromonas gingivalis lipopolysaccharide in human neutrophils.
Topics: Actin Capping Proteins; Adult; Aged; Cell Culture Techniques; Chronic Periodontitis; Colchicine; Cytochalasin B; Cytochalasin D; Diabetes Complications; Female; Gingival Crevicular Fluid; Glycated Hemoglobin; Humans; Lipopolysaccharides; Male; Middle Aged; Neutrophils; Nocodazole; Nucleic Acid Synthesis Inhibitors; Periodontal Index; Periodontal Pocket; Periodontitis; Porphyromonas gingivalis; Resistin; Tubulin Modulators | 2012 |
Rab6-mediated retrograde transport regulates inner nuclear membrane targeting of caveolin-2 in response to insulin.
Topics: Animals; Caveolin 1; Caveolin 2; Colchicine; Endoplasmic Reticulum; ets-Domain Protein Elk-1; Golgi Apparatus; HEK293 Cells; Humans; Insulin; Nocodazole; Nuclear Envelope; Nuclear Pore Complex Proteins; Point Mutation; Protein Transport; rab GTP-Binding Proteins; Rats; RNA, Small Interfering; STAT3 Transcription Factor; Transcriptional Activation; Tubulin Modulators | 2012 |
Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.
Topics: Animals; Calcium Signaling; Cardiomegaly; Cardiomyopathies; Cells, Cultured; Colchicine; Disease Models, Animal; Excitation Contraction Coupling; Heart Failure; Humans; Kinesins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubules; Muscle Proteins; Myocytes, Cardiac; Nocodazole; Sarcolemma; Tubulin Modulators | 2014 |
NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents.
Topics: Animals; Axons; Colchicine; Comet Assay; Cytoskeleton; Ganglia, Spinal; Gene Expression Regulation; Humans; MCF-7 Cells; Microtubules; Mitochondria; NAD; Neurons; Nocodazole; Polymers; Rats; Reactive Oxygen Species; Sirtuin 3; Tubulin Modulators; Vinblastine | 2014 |
Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity.
Topics: Animals; Axonal Transport; Brain-Derived Neurotrophic Factor; Cells, Cultured; Colchicine; CREB-Binding Protein; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Interleukin-6; Male; Mice; Mice, Inbred ICR; Nociceptive Pain; Nocodazole; Protein Transport; Quinazolinones; Sciatic Nerve; Sensory Receptor Cells; Tubulin Modulators | 2014 |
Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing.
Topics: Albendazole; Animals; Benzimidazoles; Bystander Effect; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Colchicine; Cytokines; HT29 Cells; Humans; Interferon Type I; Mice; Microtubules; Nocodazole; Oncolytic Virotherapy; Oncolytic Viruses; Protein Biosynthesis; Rhabdoviridae; Rhabdoviridae Infections; RNA, Messenger; Tubulin Modulators; Vero Cells; Vinblastine; Vinorelbine | 2015 |
Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Colchicine; Cytochalasin D; Cytoskeleton; Elongation Factor 2 Kinase; Gene Expression Regulation; Growth Cones; Microtubules; Nerve Growth Factors; Nerve Tissue Proteins; Netrin-1; Nocodazole; Oocytes; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Elongation Factor 2; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Processing, Post-Translational; Signal Transduction; Thiazolidines; Tubulin Modulators; Tumor Suppressor Proteins; Xenopus laevis; Xenopus Proteins | 2015 |
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.
Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Carrier Proteins; Caspases; Cell Line, Tumor; Chromatin; Colchicine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Microfilament Proteins; Necrosis; Neurons; Nocodazole; Peptidomimetics; Quinolines; Rotenone; Signal Transduction; Staurosporine; Thapsigargin | 2015 |
Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Topics: Animals; Antineoplastic Agents; Binding Sites; Colchicine; Diketopiperazines; Drug Discovery; Ligands; Microtubules; Models, Molecular; Molecular Structure; Nocodazole; Protein Kinase Inhibitors; Protein Kinases; Pyrrolidinones; Quinolines; Structure-Activity Relationship; Swine; Tubulin; Tubulin Modulators | 2016 |
Genetically encoded live-cell sensor for tyrosinated microtubules.
Topics: Colchicine; Cytoskeleton; HEK293 Cells; Humans; Microtubule-Associated Proteins; Microtubules; Nocodazole; Protein Processing, Post-Translational; Tubulin; Tyrosine; Vincristine | 2020 |