nobiletin has been researched along with 3,3',4',5,6,7,8-heptamethoxyflavone in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 8 (61.54) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beutler, JA; Boyd, MR; Cardellina, JH; Haemers, A; Hamel, E; Rajan, P; Roitman, JN; Vlietinck, AJ | 1 |
| Ash, K; Grohmann, K; Manthey, CL; Manthey, JA; Montanari, A | 1 |
| Matsuo, H; Morimoto, S; Ohnishi, A; Ohtani, H; Sawada, Y; Shoyama, Y; Takanaga, H; Yamada, S | 1 |
| Arcas, MC; Botía, JM; Del Río, JA; Fuster, MD; Ortuño, A | 1 |
| Dushenkov, S; Ho, CT; Lai, CS; Li, S; Lo, CY; Pan, MH | 1 |
| Akita, K; Fujii, M; Hirata, T; Hongo, D; Kuroyanagi, M; Ogawa, K; Yanaka, N | 1 |
| Bönisch, H; Haenisch, B; Mayer, R; Müller, CE; Müller, H; Pajeva, IK; Pick, A; Weigt, M; Wiese, M | 1 |
| Ikegawa, T; Koyabu, N; Morimoto, S; Naito, M; Ohtani, H; Sawada, Y; Shoyama, Y; Tsuruo, T; Ushigome, F | 1 |
| Furukawa, H; Ito, C; Iwase, Y; Ju-ichi, M; Kuchide, M; Mukainaka, T; Nishino, H; Takemura, Y; Tokuda, H; Yano, M | 1 |
| Chen, L; Qian, S | 1 |
| Ando, H; Sasaki, K; Tateoka, N; Yoshizaki, F | 1 |
| Ho, CT; Jin, H; Li, S; Patel, T; Xiao, H; Yang, CS | 1 |
| Hashizume, R; Masaki, H; Yoshizaki, N | 1 |
13 other study(ies) available for nobiletin and 3,3',4',5,6,7,8-heptamethoxyflavone
| Article | Year |
|---|---|
Structure-activity requirements for flavone cytotoxicity and binding to tubulin.
Topics: Antineoplastic Agents, Phytogenic; Biopolymers; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Flavonoids; Humans; Protein Binding; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured | 1998 |
Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human monocytes.
Topics: Citrus; Cyclic AMP; Flavonoids; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Phosphodiesterase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 1999 |
Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beverages; Caco-2 Cells; Cell Survival; Citrus; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Flavones; Flavonoids; Humans; Hydroxylation; Liver; LLC-PK1 Cells; Mixed Function Oxygenases; Solvents; Swine; Testosterone; Vinblastine | 2000 |
Increasing resistance against Phytophthora citrophthora in tangelo Nova fruits by modulating polymethoxyflavones levels.
Topics: Adenine; Benzyl Compounds; Citrus; Flavones; Flavonoids; Kinetin; Phytophthora; Plant Diseases; Purines | 2002 |
Isolation and syntheses of polymethoxyflavones and hydroxylated polymethoxyflavones as inhibitors of HL-60 cell lines.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Chromatography, High Pressure Liquid; Citrus; Flavones; Fruit; HL-60 Cells; Humans; Hydroxylation; Indicators and Reagents; Magnetic Resonance Spectroscopy; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2007 |
Identification and physiological evaluation of the components from citrus fruits as potential drugs for anti-corpulence and anticancer.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Antineoplastic Agents; Cell Line, Tumor; Citrus; Coumarins; Drug Evaluation, Preclinical; Flavones; Humans; Mice | 2009 |
Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Flavonoids; Humans; Hydrogen Bonding; Models, Molecular; Neoplasm Proteins; Quantitative Structure-Activity Relationship | 2011 |
Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells.
Topics: Acetates; ATP Binding Cassette Transporter, Subfamily B; Beverages; Blotting, Western; Citrus; Cyclosporine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavones; Flavonoids; Furocoumarins; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Plant Extracts; Tritium; Verapamil; Vincristine | 2000 |
Cancer chemopreventive activity of 3,5,6,7,8,3',4'-heptamethoxyflavone from the peel of citrus plants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Citrus; Female; Flavones; Flavonoids; Mice; Nitro Compounds; Papilloma; Plant Extracts; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
[Studies on the chemical constituents of Citrus reticulata].
Topics: Citrus; Flavones; Flavonoids; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet | 1998 |
Effect of flavones on rat brain and lung matrix metalloproteinase activity measured by film in-situ zymography.
Topics: Animals; Brain; Collagen; Electrophoresis, Polyacrylamide Gel; Flavones; Flavonoids; Gelatin; Lung; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Rats; Rats, Wistar | 2005 |
Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis.
Topics: Anticarcinogenic Agents; Antioxidants; Apoptosis; Cell Division; Cell Line, Tumor; Citrus sinensis; Flavones; Flavonoids; Fruit; Humans; Hydroxylation; Lung Neoplasms; Structure-Activity Relationship | 2009 |
A polymethoxyflavone mixture extracted from orange peels, mainly containing nobiletin, 3,3',4',5,6,7,8-heptamethoxyflavone and tangeretin, suppresses melanogenesis through the acidification of cell organelles, including melanosomes.
Topics: Cell Line, Tumor; Citrus sinensis; Flavones; Flavonoids; Humans; Hydrogen-Ion Concentration; Lysosomes; Melanins; Melanosomes; Monophenol Monooxygenase; Plant Extracts | 2017 |