Page last updated: 2024-08-25

nobiletin and 3',4'-didemethylnobiletin

nobiletin has been researched along with 3',4'-didemethylnobiletin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Dushenkov, S; Ho, CT; Lai, CS; Li, S; Lo, CY; Pan, MH1
Ho, CT; Lai, CS; Li, S; Lo, CY; Pan, MH; Sang, S; Yang, CS1
Kosano, H; Miyata, Y; Natsugari, H; Okuyama, Y; Oshitari, T; Takahashi, H2
Kosano, H; Miyata, Y; Natsugari, H; Okuyama, Y; Oshitari, T; Shimada, A; Takahashi, H1
Chai, CY; Dushenkov, S; Ho, CT; Lai, CS; Li, S; Lo, CY; Pan, MH; Wang, YJ1
Ho, CT; Kou, MC; Li, S; Lo, YH; Pan, MH; Wu, MJ; Yen, JH1
Ho, CT; Li, S; Lin, MH; Su, JD; Weng, CY; Wu, MJ; Yen, JH1
Gao, Z; Song, M; Wang, M; Wu, X; Xiao, H; Xu, F; Zhang, G; Zheng, J1
DiMarco-Crook, C; Du, Z; Li, Z; Rakariyatham, K; Wu, X; Xiao, H; Zheng, J1

Other Studies

10 other study(ies) available for nobiletin and 3',4'-didemethylnobiletin

ArticleYear
Isolation and syntheses of polymethoxyflavones and hydroxylated polymethoxyflavones as inhibitors of HL-60 cell lines.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Chromatography, High Pressure Liquid; Citrus; Flavones; Fruit; HL-60 Cells; Humans; Hydroxylation; Indicators and Reagents; Magnetic Resonance Spectroscopy; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet

2007
Anti-inflammatory property of the urinary metabolites of nobiletin in mouse.
    Bioorganic & medicinal chemistry letters, 2007, Sep-15, Volume: 17, Issue:18

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Chromatography, High Pressure Liquid; Flavones; Mice; Tandem Mass Spectrometry

2007
Nobiletin metabolites: synthesis and inhibitory activity against matrix metalloproteinase-9 production.
    Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

    Topics: Acetophenones; Epithelial Cells; Flavones; Humans; Hydroxybenzoates; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors

2011
B-Ring-modified and/or 5-demethylated nobiletin congeners: inhibitory activity against pro-MMP-9 production.
    Bioorganic & medicinal chemistry, 2011, Dec-01, Volume: 19, Issue:23

    Topics: Cell Line; Enzyme Precursors; Epithelial Cells; Flavones; Humans; Lens, Crystalline; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Protease Inhibitors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2011
Polymethoxyflavones as agents that prevent formation of cataract: nobiletin congeners show potent growth inhibitory effects in human lens epithelial cells.
    Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1

    Topics: Cataract; Cell Line; Cell Movement; Cell Proliferation; Citrus; Epithelial Cells; Flavones; Humans; Lens, Crystalline; Matrix Metalloproteinase 9; Structure-Activity Relationship

2013
Anti-inflammatory and antitumor promotional effects of a novel urinary metabolite, 3',4'-didemethylnobiletin, derived from nobiletin.
    Carcinogenesis, 2008, Volume: 29, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Benz(a)Anthracenes; Blotting, Western; Carcinogenicity Tests; Cyclooxygenase 2; Electrophoretic Mobility Shift Assay; Female; Flavones; Gene Expression; Immunohistochemistry; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Proliferating Cell Nuclear Antigen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Skin Neoplasms; Transcription Factor AP-1

2008
Nobiletin metabolite, 3',4'-dihydroxy-5,6,7,8-tetramethoxyflavone, inhibits LDL oxidation and down-regulates scavenger receptor expression and activity in THP-1 cells.
    Biochimica et biophysica acta, 2010, Volume: 1801, Issue:2

    Topics: Animals; CD11b Antigen; CD36 Antigens; Cell Differentiation; Cells, Cultured; Down-Regulation; Flavones; Flow Cytometry; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Mice; Monocytes; Oxidation-Reduction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Scavenger Receptors, Class A; Scavenger Receptors, Class E; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances

2010
3',4'-didemethylnobiletin induces phase II detoxification gene expression and modulates PI3K/Akt signaling in PC12 cells.
    Free radical biology & medicine, 2012, Jan-01, Volume: 52, Issue:1

    Topics: Animals; Antioxidants; Cell Survival; Flavones; Gene Expression; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Hydrogen Peroxide; Metabolic Detoxication, Phase II; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction

2012
Chemopreventive effects of nobiletin and its colonic metabolites on colon carcinogenesis.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:12

    Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Colitis; Colonic Neoplasms; Cytokines; Flavones; Humans; Male; Mice, Inbred Strains; Neoplasms, Experimental

2015
Synergistic anticancer effects of curcumin and 3',4'-didemethylnobiletin in combination on colon cancer cells.
    Journal of food science, 2020, Volume: 85, Issue:4

    Topics: Anticarcinogenic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Curcumin; Drug Synergism; Flavones; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans

2020