no 711 has been researched along with tiagabine in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Borden, LA; Branchek, TA; Gluchowski, C; Murali Dhar, TG; Smith, KE; Weinshank, RL | 1 |
| Höfner, G; Kragler, A; Wanner, KT | 1 |
| Lutz, TA; Petrera, M; Sindelar, M; Wanner, KT | 1 |
| Hauke, TJ; Höfner, G; Wanner, KT; Wein, T | 1 |
| Kern, F; Wanner, KT | 1 |
| Höfner, G; Huber, SK; Wanner, KT | 1 |
| Fijałkowski, Ł; Furgała, A; Gryzło, B; Höfner, GC; Kulig, K; Malawska, B; Malawska, K; Nowaczyk, A; Podkowa, A; Rapacz, A; Sałat, K; Wanner, KT; Zaręba, P; Żmudzki, P | 1 |
7 other study(ies) available for no 711 and tiagabine
| Article | Year |
|---|---|
Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.
Topics: Animals; Anticonvulsants; Carrier Proteins; Cell Line; Cloning, Molecular; GABA Antagonists; GABA Plasma Membrane Transport Proteins; Humans; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nicotinic Acids; Nipecotic Acids; Organic Anion Transporters; Oximes; Pyridines; Rats; Recombinant Proteins; Structure-Activity Relationship; Tiagabine; Transfection | 1994 |
Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1-mGAT4.
Topics: Animals; Benzylamines; Cell Line; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Humans; Methylation; Mice; Molecular Structure; Structure-Activity Relationship | 2008 |
Focused pseudostatic hydrazone libraries screened by mass spectrometry binding assay: optimizing affinities toward γ-aminobutyric acid transporter 1.
Topics: GABA Plasma Membrane Transport Proteins; Hydrazones; Mass Spectrometry | 2013 |
Novel Allosteric Ligands of γ-Aminobutyric Acid Transporter 1 (GAT1) by MS Based Screening of Pseudostatic Hydrazone Libraries.
Topics: Aldehydes; Allosteric Regulation; Drug Evaluation, Preclinical; GABA Plasma Membrane Transport Proteins; Humans; Hydrazones; Ligands; Mass Spectrometry; Models, Molecular; Protein Conformation | 2018 |
Screening oxime libraries by means of mass spectrometry (MS) binding assays: Identification of new highly potent inhibitors to optimized inhibitors γ-aminobutyric acid transporter 1.
Topics: Binding Sites; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; HEK293 Cells; Humans; Mass Spectrometry; Molecular Structure; N-Acetylglucosaminyltransferases; Oximes; Small Molecule Libraries; Structure-Activity Relationship | 2019 |
Application of the concept of oxime library screening by mass spectrometry (MS) binding assays to pyrrolidine-3-carboxylic acid derivatives as potential inhibitors of γ-aminobutyric acid transporter 1 (GAT1).
Topics: GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; Oximes; Pyrrolidines; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2019 |
Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; Hyperalgesia; Male; Mice; Molecular Docking Simulation; Molecular Structure; Neuralgia; Oxaliplatin; Pain Threshold; Protein Binding; Streptozocin; Structure-Activity Relationship | 2020 |