nnc 711 has been researched along with nipecotic acid in 12 studies
| Studies (nnc 711) | Trials (nnc 711) | Recent Studies (post-2010) (nnc 711) | Studies (nipecotic acid) | Trials (nipecotic acid) | Recent Studies (post-2010) (nipecotic acid) |
|---|---|---|---|---|---|
| 112 | 0 | 21 | 308 | 0 | 43 |
| Protein | Taxonomy | nnc 711 (IC50) | nipecotic acid (IC50) |
|---|---|---|---|
| Sodium- and chloride-dependent GABA transporter 1 | Homo sapiens (human) | 5.3367 | |
| Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (house mouse) | 8.1516 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Chapman, AG; Meldrum, BS; Parvez, NS; Smith, SE | 1 |
| Chen, DZ; Katsura, M; Kuriyama, K; Narihara, H; Ohkuma, S | 1 |
| Nicklas, WJ; Zeevalk, GD | 1 |
| Bernard, LP; Nicklas, WJ; Stokes, AH; Zeevalk, GD | 1 |
| Mac, M; Nałecz, KA; Nałecz, MJ; Sacher, A; Wawrzeńczyk, A | 1 |
| Himmelreich, NH; Linetska, MV; Storchak, LG; Tarasenko, AS | 1 |
| Hablitz, JJ; Keros, S | 1 |
| Kreil, A; Richter, A | 1 |
| Marino, V; Nassery, K; Parker, DA | 1 |
| De Mello, FG; De Mello, MC; De Melo Reis, RA; De Sampaio Schitine, C; Kubrusly, RC; Yamasaki, EN | 1 |
| Allen, CN; Cravetchi, O; Moldavan, M | 1 |
12 other study(ies) available for nnc 711 and nipecotic acid
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
The gamma-aminobutyric acid uptake inhibitor, tiagabine, is anticonvulsant in two animal models of reflex epilepsy.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Epilepsy; Female; GABA Agents; Male; Motor Activity; Myoclonus; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Oximes; Papio; Photic Stimulation; Proline; Rats; Rats, Inbred Strains; Tiagabine | 1995 |
Nitric oxide-evoked [3H] gamma-aminobutyric acid release is mediated by two distinct release mechanisms.
Topics: Animals; Biological Transport; Calcium; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Mice; Neurons; Nipecotic Acids; Nitric Oxide; Nitroprusside; Oximes; Penicillamine; Proline; S-Nitroso-N-Acetylpenicillamine; Sodium; Tritium | 1996 |
Activity at the GABA transporter contributes to acute cellular swelling produced by metabolic impairment in retina.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Chick Embryo; Culture Techniques; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glycolysis; Iodoacetates; Ischemia; Isoxazoles; Membrane Proteins; Membrane Transport Proteins; Muscimol; Nipecotic Acids; Organic Anion Transporters; Oximes; Proline; Retina | 1997 |
Attenuation of malonate toxicity in primary mesencephalic cultures using the GABA transport blocker, NO-711.
Topics: Animals; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Malonates; Mesencephalon; Muscimol; Neurons; Nipecotic Acids; Oximes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2001 |
Transport of L-carnitine in isolated cerebral cortex neurons.
Topics: Animals; beta-Alanine; Betaine; Binding, Competitive; Biological Transport, Active; Carnitine; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Proteins; Membrane Transport Proteins; Neurons; Nipecotic Acids; Oocytes; Organic Anion Transporters; Organic Cation Transport Proteins; Oximes; Rats; Rats, Wistar; Solute Carrier Family 22 Member 5; Taurine; Xenopus laevis | 2001 |
Involvement of membrane GABA transporter in alpha-latrotoxin-stimulated [3H]GABA release.
Topics: Algorithms; Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carrier Proteins; Cell Membrane; Enzyme Inhibitors; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ionophores; Macrolides; Male; Membrane Proteins; Membrane Transport Proteins; Nipecotic Acids; Organic Anion Transporters; Oximes; Rats; Rats, Wistar; Spider Venoms; Stimulation, Chemical; Synaptic Transmission; Synaptosomes | 2004 |
Subtype-specific GABA transporter antagonists synergistically modulate phasic and tonic GABAA conductances in rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Anisoles; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Synergism; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Membrane Transport Modulators; Membrane Transport Proteins; Models, Neurological; Muscimol; Neocortex; Neural Inhibition; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors | 2005 |
Antidystonic efficacy of gamma-aminobutyric acid uptake inhibitors in the dtsz mutant.
Topics: Animals; Cricetinae; Disease Progression; Dose-Response Relationship, Drug; Dystonia; Female; GABA Antagonists; Injections, Intraperitoneal; Male; Mutation; Nipecotic Acids; Oximes; Random Allocation; Severity of Illness Index; Tiagabine; Time Factors; Treatment Outcome | 2005 |
Uptake and release of [(3)H]GABA in human dental pulp.
Topics: Adult; Autoreceptors; Baclofen; Dental Pulp; Electric Stimulation; Female; GABA Agents; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Male; Morpholines; Nipecotic Acids; Oximes; Radiopharmaceuticals; Receptors, GABA; Time Factors; Tritium | 2007 |
GABA uptake by purified avian Müller glia cells in culture.
Topics: Analysis of Variance; Animals; Biological Transport; Cells, Cultured; Chick Embryo; Chlorides; Coculture Techniques; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Neuroglia; Neurons; Nipecotic Acids; Oximes; Retina; Sodium; Temperature; Tritium | 2007 |
GABA transporters regulate tonic and synaptic GABA
Topics: Animals; Anisoles; GABA Antagonists; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; Male; Neurons; Nipecotic Acids; Oximes; Period Circadian Proteins; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Suprachiasmatic Nucleus; Synaptic Potentials | 2017 |