nitroxyl has been researched along with cyclic gmp in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 11 (52.38) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Chaudhuri, G; Chiang, K; Fukuto, JM; Hszieh, R; Wong, P | 1 |
| De Koster, BM; Elferink, JG; Van Der Zee, J; Vansteveninck, J; Vanuffelen, BE | 1 |
| Bhan, I; Cheung, WS; Lipton, SA | 1 |
| Espey, MG; Feelisch, M; Fukuto, JM; Hare, JM; Isoda, T; Kass, DA; Martignani, C; Miranda, KM; Paolocci, N; Saavedra, WF; Wink, DA | 1 |
| Champion, HC; Fukuto, JM; Kass, DA; Katori, T; Miranda, KM; Paolocci, N; St John, ME; Wink, DA | 1 |
| Alberto, F; Bari, SE; Bermejo, E; Lazzari, MA; Rosenstein, RE; Sáenz, DA | 1 |
| Champion, HC; Cologna, SM; Dutton, AS; Fukuto, JM; Houk, KN; Kass, DA; Katori, T; Keefer, LK; Mancardi, D; McLendon, WJ; Miranda, KM; Paolocci, N; Ridnour, LA; Saavedra, JE; Thomas, L; Tocchetti, CG; Torres de Holding, CL; Wink, DA | 1 |
| Favaloro, JL; Kemp-Harper, BK | 1 |
| Paolocci, N; Wink, DA | 1 |
| Bian, JS; Hu, LF; Huang, D; Wang, S; Yong, QC | 1 |
| Irvine, JC; Kemp-Harper, BK; Widdop, RE | 1 |
| Alexander, AE; Cao, AH; Irvine, JC; Kaye, DM; Kemp-Harper, BK; Lin, EQ; Love, JE; McMullen, JR; Patel, R; Ritchie, RH | 1 |
| Batenburg, WW; Botden, IP; Danser, AH; de Vries, R; Langendonk, JG; Sijbrands, EJ | 1 |
| Alexander, AE; Cao, N; Gossain, S; Horowitz, JD; Irvine, JC; Kemp-Harper, BK; Love, JE; Qin, C; Ritchie, RH | 1 |
| Chirkov, YY; Dautov, RF; Horowitz, JD; Kemp-Harper, BK; Licari, G; Liu, S; Ngo, DT; Ritchie, RH; Sverdlov, AL | 1 |
| Alves-Filho, JC; Casagrande, R; Cunha, FQ; Cunha, TM; Ferreira, SH; Longhi-Balbinot, DT; Marchesi, M; Miranda, KM; Staurengo-Ferrari, L; Verri, WA; Zarpelon, AC | 1 |
| Berkowitz, DE; Friebe, A; Groneberg, D; Hori, D; Kass, DA; Nakamura, T; Paolocci, N; Ranek, MJ; Sikka, G; Takimoto, E; Zhu, G | 1 |
| Andrews, KL; Chin-Dusting, JP; Farry, J; Jefferis, AM; Kemp-Harper, BK; Lumsden, NG | 1 |
| Alves-Filho, JC; Bertozzi, MM; Casagrande, R; Cunha, FQ; Cunha, TM; Longhi-Balbinot, DT; Miranda, KM; Peron, JP; Pinho-Ribeiro, FA; Rossaneis, AC; Verri, WA | 1 |
| Butt, E; Cuello, F; de Wit, C; Dees, C; Diering, S; Donzelli, S; Eaton, P; Feil, R; Goetz, M; Kamynina, A; King, SB; Leichert, LI; Nikolaev, VO; Polat, V; Prysyazhna, O; Schmidt, K; Schobesberger, S; Scotcher, J; Stathopoulou, K; Subramanian, H; Wolters, M | 1 |
| Cuello, F; Eaton, P; Guttzeit, S; Kamynina, A | 1 |
21 other study(ies) available for nitroxyl and cyclic gmp
| Article | Year |
|---|---|
The pharmacological activity of nitroxyl: a potent vasodilator with activity similar to nitric oxide and/or endothelium-derived relaxing factor.
Topics: Animals; Aorta; Cattle; Cyanamide; Cyclic GMP; Endothelium, Vascular; Lung; Methylene Blue; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Rabbits; Vasodilator Agents | 1992 |
Intracellular but not extracellular conversion of nitroxyl anion into nitric oxide leads to stimulation of human neutrophil migration.
Topics: Chemotaxis, Leukocyte; Cyclic GMP; Free Radicals; Humans; In Vitro Techniques; Methionine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidants | 1998 |
Nitric oxide (NO.) stabilizes whereas nitrosonium (NO+) enhances filopodial outgrowth by rat retinal ganglion cells in vitro.
Topics: Animals; Antioxidants; Cells, Cultured; Cyclic GMP; Cysteine; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroso Compounds; Pseudopodia; Rats; Rats, Long-Evans; Retinal Ganglion Cells; S-Nitrosothiols | 2000 |
Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.
Topics: Animals; Anions; Baroreflex; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cyclic GMP; Dogs; Male; Myocardial Contraction; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Peptide Fragments; Signal Transduction | 2001 |
Positive inotropic and lusitropic effects of HNO/NO- in failing hearts: independence from beta-adrenergic signaling.
Topics: Animals; Calcitonin Gene-Related Peptide; Cyclic GMP; Dogs; Heart Failure; Myocardial Contraction; Nitrogen Oxides; Receptors, Adrenergic, beta; Signal Transduction | 2003 |
Effect of nitroxyl on human platelets function.
Topics: Adenosine Triphosphate; Antigens, CD; Blood Platelets; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Humans; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroprusside; P-Selectin; Platelet Aggregation; Platelet Membrane Glycoproteins; Tetraspanin 30; Time Factors | 2005 |
Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo.
Topics: Animals; Azo Compounds; Calcitonin Gene-Related Peptide; Cardiovascular System; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Cyclic GMP; Dogs; Glutathione; Hemodynamics; Hydrazines; Lethal Dose 50; Male; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Uric Acid | 2005 |
Redox variants of NO (NO{middle dot} and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms.
Topics: 4-Aminopyridine; Animals; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vascular Resistance; Vasodilation; Vasodilator Agents | 2009 |
The shy Angeli and his elusive creature: the HNO route to vasodilation.
Topics: Animals; Biological Factors; Cyclic GMP; Guanylate Cyclase; Humans; Membrane Potentials; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Potassium Channels, Voltage-Gated; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vascular Resistance; Vasodilation; Vasodilator Agents | 2009 |
Hydrogen sulfide interacts with nitric oxide in the heart: possible involvement of nitroxyl.
Topics: Animals; Caffeine; Calcium; Cyclic AMP; Cyclic GMP; Diethylamines; Hydrogen Sulfide; Models, Animal; Myocardium; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitroprusside; Rats; Rats, Sprague-Dawley | 2010 |
Chronic administration of the HNO donor Angeli's salt does not lead to tolerance, cross-tolerance, or endothelial dysfunction: comparison with GTN and DEA/NO.
Topics: Acetylcholine; Animals; Aorta; Cyclic GMP; Diethylamines; In Vitro Techniques; Male; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroglycerin; Rats | 2011 |
Nitroxyl (HNO) stimulates soluble guanylyl cyclase to suppress cardiomyocyte hypertrophy and superoxide generation.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Adhesion Molecules; Cyclic GMP; Endothelin-1; Guanylate Cyclase; Microfilament Proteins; Myocytes, Cardiac; NADPH Oxidases; Natriuretic Peptide, Brain; Nitrites; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Rats; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Superoxides | 2012 |
Nitrite- and nitroxyl-induced relaxation in porcine coronary (micro-) arteries: underlying mechanisms and role as endothelium-derived hyperpolarizing factor(s).
Topics: Animals; Biological Factors; Coronary Vessels; Cyclic GMP; Guanylate Cyclase; Nitrites; Nitrogen Oxides; Receptors, Cytoplasmic and Nuclear; Sodium-Potassium-Exchanging ATPase; Soluble Guanylyl Cyclase; Swine; Ultraviolet Rays; Vasodilation; Wine | 2012 |
HNO/cGMP-dependent antihypertrophic actions of isopropylamine-NONOate in neonatal rat cardiomyocytes: potential therapeutic advantages of HNO over NO.
Topics: Animals; Animals, Newborn; Antioxidants; Cardiomegaly; Cardiovascular Agents; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Guanylate Cyclase; Hydrazines; Myocytes, Cardiac; Nitric Oxide Donors; Nitrogen Oxides; Pyrogallol; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Second Messenger Systems; Soluble Guanylyl Cyclase; Time Factors | 2013 |
The nitric oxide redox sibling nitroxyl partially circumvents impairment of platelet nitric oxide responsiveness.
Topics: Aged; Aged, 80 and over; Blood Platelets; Case-Control Studies; Cyclic GMP; Female; Humans; Hydrazines; Male; Middle Aged; Myocardial Ischemia; Nitric Oxide; Nitrogen Oxides; Nitroprusside; Oxidation-Reduction; Platelet Aggregation | 2013 |
Nitroxyl inhibits overt pain-like behavior in mice: role of cGMP/PKG/ATP-sensitive potassium channel signaling pathway.
Topics: Analgesics; Animals; Behavior, Animal; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; KATP Channels; Male; Mice; Nitrogen Oxides; Pain; Pain Measurement; Signal Transduction | 2014 |
Soluble guanylate cyclase is required for systemic vasodilation but not positive inotropy induced by nitroxyl in the mouse.
Topics: Animals; Aorta; Cardiotonic Agents; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cysteine; Guanylate Cyclase; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxidation-Reduction; Receptors, Cytoplasmic and Nuclear; Second Messenger Systems; Soluble Guanylyl Cyclase; Sulfonamides; Vasodilation | 2015 |
Nitroxyl: a vasodilator of human vessels that is not susceptible to tolerance.
Topics: Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Guanylate Cyclase; Humans; In Vitro Techniques; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroglycerin; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Radial Artery; Receptors, Cytoplasmic and Nuclear; Saphenous Vein; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2015 |
The nitroxyl donor, Angeli's salt, reduces chronic constriction injury-induced neuropathic pain.
Topics: Adenosine Triphosphate; Analgesics; Animals; Astrocytes; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Gene Expression Regulation; Hyperalgesia; Interleukin-1beta; Interleukin-33; Male; Mice; Microglia; Neuralgia; Neuroprotective Agents; Nitrogen Oxides; Sciatic Nerve; Signal Transduction; Spinal Cord; Tumor Necrosis Factor-alpha | 2016 |
Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity.
Topics: Animals; Catalytic Domain; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cysteine; Disulfides; Fluorescence Resonance Energy Transfer; HEK293 Cells; Humans; Male; Mass Spectrometry; Mice; Muscle, Smooth, Vascular; Mutagenesis, Site-Directed; Nitrogen Oxides; Oxidation-Reduction | 2017 |
Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I.
Topics: Animals; Blood Pressure; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Guanosine; Guanosine Monophosphate; Hypertension; Hypotension; Mice; Nitrogen Oxides; Protein Kinases | 2022 |