nitroxyl and cyclic gmp

nitroxyl has been researched along with cyclic gmp in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's7 (33.33)29.6817
2010's11 (52.38)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Chaudhuri, G; Chiang, K; Fukuto, JM; Hszieh, R; Wong, P1
De Koster, BM; Elferink, JG; Van Der Zee, J; Vansteveninck, J; Vanuffelen, BE1
Bhan, I; Cheung, WS; Lipton, SA1
Espey, MG; Feelisch, M; Fukuto, JM; Hare, JM; Isoda, T; Kass, DA; Martignani, C; Miranda, KM; Paolocci, N; Saavedra, WF; Wink, DA1
Champion, HC; Fukuto, JM; Kass, DA; Katori, T; Miranda, KM; Paolocci, N; St John, ME; Wink, DA1
Alberto, F; Bari, SE; Bermejo, E; Lazzari, MA; Rosenstein, RE; Sáenz, DA1
Champion, HC; Cologna, SM; Dutton, AS; Fukuto, JM; Houk, KN; Kass, DA; Katori, T; Keefer, LK; Mancardi, D; McLendon, WJ; Miranda, KM; Paolocci, N; Ridnour, LA; Saavedra, JE; Thomas, L; Tocchetti, CG; Torres de Holding, CL; Wink, DA1
Favaloro, JL; Kemp-Harper, BK1
Paolocci, N; Wink, DA1
Bian, JS; Hu, LF; Huang, D; Wang, S; Yong, QC1
Irvine, JC; Kemp-Harper, BK; Widdop, RE1
Alexander, AE; Cao, AH; Irvine, JC; Kaye, DM; Kemp-Harper, BK; Lin, EQ; Love, JE; McMullen, JR; Patel, R; Ritchie, RH1
Batenburg, WW; Botden, IP; Danser, AH; de Vries, R; Langendonk, JG; Sijbrands, EJ1
Alexander, AE; Cao, N; Gossain, S; Horowitz, JD; Irvine, JC; Kemp-Harper, BK; Love, JE; Qin, C; Ritchie, RH1
Chirkov, YY; Dautov, RF; Horowitz, JD; Kemp-Harper, BK; Licari, G; Liu, S; Ngo, DT; Ritchie, RH; Sverdlov, AL1
Alves-Filho, JC; Casagrande, R; Cunha, FQ; Cunha, TM; Ferreira, SH; Longhi-Balbinot, DT; Marchesi, M; Miranda, KM; Staurengo-Ferrari, L; Verri, WA; Zarpelon, AC1
Berkowitz, DE; Friebe, A; Groneberg, D; Hori, D; Kass, DA; Nakamura, T; Paolocci, N; Ranek, MJ; Sikka, G; Takimoto, E; Zhu, G1
Andrews, KL; Chin-Dusting, JP; Farry, J; Jefferis, AM; Kemp-Harper, BK; Lumsden, NG1
Alves-Filho, JC; Bertozzi, MM; Casagrande, R; Cunha, FQ; Cunha, TM; Longhi-Balbinot, DT; Miranda, KM; Peron, JP; Pinho-Ribeiro, FA; Rossaneis, AC; Verri, WA1
Butt, E; Cuello, F; de Wit, C; Dees, C; Diering, S; Donzelli, S; Eaton, P; Feil, R; Goetz, M; Kamynina, A; King, SB; Leichert, LI; Nikolaev, VO; Polat, V; Prysyazhna, O; Schmidt, K; Schobesberger, S; Scotcher, J; Stathopoulou, K; Subramanian, H; Wolters, M1
Cuello, F; Eaton, P; Guttzeit, S; Kamynina, A1

Other Studies

21 other study(ies) available for nitroxyl and cyclic gmp

ArticleYear
The pharmacological activity of nitroxyl: a potent vasodilator with activity similar to nitric oxide and/or endothelium-derived relaxing factor.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2

    Topics: Animals; Aorta; Cattle; Cyanamide; Cyclic GMP; Endothelium, Vascular; Lung; Methylene Blue; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Rabbits; Vasodilator Agents

1992
Intracellular but not extracellular conversion of nitroxyl anion into nitric oxide leads to stimulation of human neutrophil migration.
    The Biochemical journal, 1998, Mar-01, Volume: 330 ( Pt 2)

    Topics: Chemotaxis, Leukocyte; Cyclic GMP; Free Radicals; Humans; In Vitro Techniques; Methionine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidants

1998
Nitric oxide (NO.) stabilizes whereas nitrosonium (NO+) enhances filopodial outgrowth by rat retinal ganglion cells in vitro.
    Brain research, 2000, Jun-16, Volume: 868, Issue:1

    Topics: Animals; Antioxidants; Cells, Cultured; Cyclic GMP; Cysteine; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroso Compounds; Pseudopodia; Rats; Rats, Long-Evans; Retinal Ganglion Cells; S-Nitrosothiols

2000
Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Aug-28, Volume: 98, Issue:18

    Topics: Animals; Anions; Baroreflex; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cyclic GMP; Dogs; Male; Myocardial Contraction; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Peptide Fragments; Signal Transduction

2001
Positive inotropic and lusitropic effects of HNO/NO- in failing hearts: independence from beta-adrenergic signaling.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Apr-29, Volume: 100, Issue:9

    Topics: Animals; Calcitonin Gene-Related Peptide; Cyclic GMP; Dogs; Heart Failure; Myocardial Contraction; Nitrogen Oxides; Receptors, Adrenergic, beta; Signal Transduction

2003
Effect of nitroxyl on human platelets function.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:3

    Topics: Adenosine Triphosphate; Antigens, CD; Blood Platelets; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Humans; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroprusside; P-Selectin; Platelet Aggregation; Platelet Membrane Glycoproteins; Tetraspanin 30; Time Factors

2005
Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo.
    Journal of medicinal chemistry, 2005, Dec-29, Volume: 48, Issue:26

    Topics: Animals; Azo Compounds; Calcitonin Gene-Related Peptide; Cardiovascular System; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Cyclic GMP; Dogs; Glutathione; Hemodynamics; Hydrazines; Lethal Dose 50; Male; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Uric Acid

2005
Redox variants of NO (NO{middle dot} and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: 4-Aminopyridine; Animals; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxadiazoles; Oxidation-Reduction; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vascular Resistance; Vasodilation; Vasodilator Agents

2009
The shy Angeli and his elusive creature: the HNO route to vasodilation.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Animals; Biological Factors; Cyclic GMP; Guanylate Cyclase; Humans; Membrane Potentials; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Potassium Channels, Voltage-Gated; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vascular Resistance; Vasodilation; Vasodilator Agents

2009
Hydrogen sulfide interacts with nitric oxide in the heart: possible involvement of nitroxyl.
    Cardiovascular research, 2010, Dec-01, Volume: 88, Issue:3

    Topics: Animals; Caffeine; Calcium; Cyclic AMP; Cyclic GMP; Diethylamines; Hydrogen Sulfide; Models, Animal; Myocardium; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitroprusside; Rats; Rats, Sprague-Dawley

2010
Chronic administration of the HNO donor Angeli's salt does not lead to tolerance, cross-tolerance, or endothelial dysfunction: comparison with GTN and DEA/NO.
    Antioxidants & redox signaling, 2011, May-01, Volume: 14, Issue:9

    Topics: Acetylcholine; Animals; Aorta; Cyclic GMP; Diethylamines; In Vitro Techniques; Male; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroglycerin; Rats

2011
Nitroxyl (HNO) stimulates soluble guanylyl cyclase to suppress cardiomyocyte hypertrophy and superoxide generation.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Angiotensin II; Animals; Cardiomegaly; Cell Adhesion Molecules; Cyclic GMP; Endothelin-1; Guanylate Cyclase; Microfilament Proteins; Myocytes, Cardiac; NADPH Oxidases; Natriuretic Peptide, Brain; Nitrites; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Rats; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Superoxides

2012
Nitrite- and nitroxyl-induced relaxation in porcine coronary (micro-) arteries: underlying mechanisms and role as endothelium-derived hyperpolarizing factor(s).
    Pharmacological research, 2012, Volume: 66, Issue:5

    Topics: Animals; Biological Factors; Coronary Vessels; Cyclic GMP; Guanylate Cyclase; Nitrites; Nitrogen Oxides; Receptors, Cytoplasmic and Nuclear; Sodium-Potassium-Exchanging ATPase; Soluble Guanylyl Cyclase; Swine; Ultraviolet Rays; Vasodilation; Wine

2012
HNO/cGMP-dependent antihypertrophic actions of isopropylamine-NONOate in neonatal rat cardiomyocytes: potential therapeutic advantages of HNO over NO.
    American journal of physiology. Heart and circulatory physiology, 2013, Aug-01, Volume: 305, Issue:3

    Topics: Animals; Animals, Newborn; Antioxidants; Cardiomegaly; Cardiovascular Agents; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Guanylate Cyclase; Hydrazines; Myocytes, Cardiac; Nitric Oxide Donors; Nitrogen Oxides; Pyrogallol; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Second Messenger Systems; Soluble Guanylyl Cyclase; Time Factors

2013
The nitric oxide redox sibling nitroxyl partially circumvents impairment of platelet nitric oxide responsiveness.
    Nitric oxide : biology and chemistry, 2013, Nov-30, Volume: 35

    Topics: Aged; Aged, 80 and over; Blood Platelets; Case-Control Studies; Cyclic GMP; Female; Humans; Hydrazines; Male; Middle Aged; Myocardial Ischemia; Nitric Oxide; Nitrogen Oxides; Nitroprusside; Oxidation-Reduction; Platelet Aggregation

2013
Nitroxyl inhibits overt pain-like behavior in mice: role of cGMP/PKG/ATP-sensitive potassium channel signaling pathway.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:4

    Topics: Analgesics; Animals; Behavior, Animal; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; KATP Channels; Male; Mice; Nitrogen Oxides; Pain; Pain Measurement; Signal Transduction

2014
Soluble guanylate cyclase is required for systemic vasodilation but not positive inotropy induced by nitroxyl in the mouse.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:2

    Topics: Animals; Aorta; Cardiotonic Agents; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cysteine; Guanylate Cyclase; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxidation-Reduction; Receptors, Cytoplasmic and Nuclear; Second Messenger Systems; Soluble Guanylyl Cyclase; Sulfonamides; Vasodilation

2015
Nitroxyl: a vasodilator of human vessels that is not susceptible to tolerance.
    Clinical science (London, England : 1979), 2015, Volume: 129, Issue:2

    Topics: Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Guanylate Cyclase; Humans; In Vitro Techniques; Nitric Oxide Donors; Nitrites; Nitrogen Oxides; Nitroglycerin; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Radial Artery; Receptors, Cytoplasmic and Nuclear; Saphenous Vein; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents

2015
The nitroxyl donor, Angeli's salt, reduces chronic constriction injury-induced neuropathic pain.
    Chemico-biological interactions, 2016, Aug-25, Volume: 256

    Topics: Adenosine Triphosphate; Analgesics; Animals; Astrocytes; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Gene Expression Regulation; Hyperalgesia; Interleukin-1beta; Interleukin-33; Male; Mice; Microglia; Neuralgia; Neuroprotective Agents; Nitrogen Oxides; Sciatic Nerve; Signal Transduction; Spinal Cord; Tumor Necrosis Factor-alpha

2016
Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity.
    Scientific reports, 2017, 08-30, Volume: 7, Issue:1

    Topics: Animals; Catalytic Domain; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cysteine; Disulfides; Fluorescence Resonance Energy Transfer; HEK293 Cells; Humans; Male; Mass Spectrometry; Mice; Muscle, Smooth, Vascular; Mutagenesis, Site-Directed; Nitrogen Oxides; Oxidation-Reduction

2017
Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I.
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:5

    Topics: Animals; Blood Pressure; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Guanosine; Guanosine Monophosphate; Hypertension; Hypotension; Mice; Nitrogen Oxides; Protein Kinases

2022