nitroglycerin has been researched along with zaprinast in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.33) | 18.7374 |
| 1990's | 18 (75.00) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aronson, WJ; Buga, GM; Bush, PA; Ignarro, LJ; Rajfer, J | 1 |
| Lappe, RW; Merkel, LA; Perrone, MH; Rivera, LM | 1 |
| Oe, H; Satake, N; Sawada, T; Shibata, S | 1 |
| Buchholz, RA; de Garavilla, L; Pagani, ED; Pratt, PF; Silver, PJ; Van Aller, GS; Volberg, ML | 1 |
| Oe, H; Satake, N; Shibata, S | 1 |
| Torphy, TJ; Zhou, HL | 1 |
| Satoh, K; Taira, N; Yamada, H; Yoneyama, F | 1 |
| Borg, C; Cavero, I; Mestre, M; Mondot, S | 1 |
| Hester, RK; Koibuchi, Y; Matsuo, M; Satake, N; Sato, N; Shibata, S | 1 |
| Furchgott, RF; Jothianandan, D; Martin, W; Villani, GM | 1 |
| Ignarro, LJ; Wood, KS | 1 |
| Hamaguchi, M; Imai, S; Ishibashi, T; Kato, K; Kawada, T | 1 |
| Bacon, E; Bode, DC; Buchholz, RA; de Garavilla, L; Dundore, RL; Hamel, LT; Lesher, GY; Silver, PJ; Singh, B; van Aller, G | 1 |
| O'Connor, B; Pagani, ED; Silver, PJ; VanAller, GS | 1 |
| Buchholz, RA; De Garavilla, L; Pratt, PF; Silver, PJ; Volberg, ML | 1 |
| Hamaguchi, M; Imai, S; Ishibashi, T; Kato, K; Kawada, T; Ohta, H; Sasage, H | 1 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Paoletti, G; Piretto, V; Trovati, M | 1 |
| Fujimoto, S; Satake, N; Shibata, S | 1 |
| Bode, DC; Buchholz, RA; De Garavilla, L; Dundore, R; Jackson, KN; Pagani, ED; Pratt, P; Silver, PJ; Volberg, ML | 1 |
| Bacon, ER; Bode, DC; de Garavilla, L; Dundore, RL; Pagani, ED; Silver, PJ | 1 |
| Fung, HL; Tabrizi-Fard, MA; Tseng, CM | 1 |
| Donahue, JK; Lawrence, JH; Marbán, E; Nagata, K | 1 |
| Fujimoto, S; Mori, M; Tsushima, H | 1 |
| Dou, D; Gao, Y; Guo, Y; Liu, J; Xu, X; Ying, L; Yu, X | 1 |
24 other study(ies) available for nitroglycerin and zaprinast
| Article | Year |
|---|---|
Nitric oxide is a potent relaxant of human and rabbit corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Electric Stimulation; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroglycerin; Nitroprusside; Penicillamine; Penis; Purinones; Rabbits; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1992 |
In vitro and in vivo interactions of nitrovasodilators and zaprinast, a cGMP-selective phosphodiesterase inhibitor.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Analysis of Variance; Animals; Coronary Vessels; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Nitroprusside; Purinones; Rats; Rats, Inbred SHR; Swine; Vasodilation; Vasodilator Agents | 1992 |
The mode of vasorelaxing action of melatonin in rabbit aorta.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Dinoprost; In Vitro Techniques; Male; Melatonin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Purinones; Rabbits; Serotonin | 1991 |
Reversal or nitroglycerin tolerance by the cGMP phosphodiesterase inhibitor zaprinast.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Pressure; Drug Tolerance; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Purinones; Rats; Rats, Inbred Strains | 1991 |
Vasorelaxing action of melatonin in rat isolated aorta; possible endothelium dependent relaxation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Endothelium, Vascular; In Vitro Techniques; Male; Melatonin; Methylene Blue; Methysergide; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Purinones; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Relationship between cyclic guanosine monophosphate accumulation and relaxation of canine trachealis induced by nitrovasodilators.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Dogs; Drug Synergism; Female; Guanylate Cyclase; Hemoglobins; Isoproterenol; Male; Methylene Blue; Muscle Relaxation; Nitroglycerin; Nitroprusside; Penicillamine; Purinones; S-Nitroso-N-Acetylpenicillamine; Time Factors; Trachea; Vasodilator Agents | 1991 |
Comparison of the effects of the novel vasodilator FK409 with those of nitroglycerin in isolated coronary artery of the dog.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Coronary Vessels; Dogs; Female; Guanylate Cyclase; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Nitro Compounds; Nitroglycerin; Prostaglandin Endoperoxides, Synthetic; Purinones; Vasodilator Agents | 1991 |
Nicorandil: differential contribution of K+ channel opening and guanylate cyclase stimulation to its vasorelaxant effects on various endothelin-1-contracted arterial preparations. Comparison to aprikalim (RP 52891) and nitroglycerin.
Topics: Animals; Coronary Vessels; Endothelins; Endothelium, Vascular; Glyburide; Guanylate Cyclase; Heart; Hemodynamics; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Picolines; Potassium Channels; Purinones; Pyrans; Rats; Rats, Inbred Strains; Stimulation, Chemical; Swine; Swine, Miniature; Vasodilator Agents | 1991 |
Characteristics of the vasorelaxing action of (3E)-4-ethyl-2-hydroximino-5-nitro-3-hexamide FK409, a new vasodilator isolated from microbial sources, in isolated rabbit arteries.
Topics: Animals; Arteries; Caffeine; Calcium; Cyclic GMP; Hemoglobins; Histamine; In Vitro Techniques; Inositol Phosphates; Male; Methylene Blue; Nitro Compounds; Nitroglycerin; Norepinephrine; Purinones; Rabbits; Serotonin; Vasoconstriction; Vasodilator Agents | 1991 |
Phosphodiesterase inhibitors induce endothelium-dependent relaxation of rat and rabbit aorta by potentiating the effects of spontaneously released endothelium-derived relaxing factor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta; Cyclic GMP; Drug Synergism; Endothelium; Hemoglobins; In Vitro Techniques; Isoproterenol; Male; Nitric Oxide; Nitroglycerin; Papaverine; Phosphodiesterase Inhibitors; Purinones; Rabbits; Rats; Rats, Inbred Strains; Vasodilation; Vasodilator Agents | 1986 |
Hepatic cyclic GMP formation is regulated by similar factors that modulate activation of purified hepatic soluble guanylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Acetaminophen; Acetylcysteine; Animals; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Heme; Liver; Methylnitronitrosoguanidine; Mice; Nitroglycerin; Penicillamine; Phenobarbital; Phenylhydrazines; Potassium Cyanide; Probenecid; Protoporphyrins; Purinones; S-Nitroso-N-Acetylpenicillamine | 1987 |
Contribution of activation of K+ channels to glyceryl trinitrate-induced relaxation of rabbit aorta.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Apamin; Charybdotoxin; Cyclic GMP; Endothelium, Vascular; Ethers, Cyclic; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Okadaic Acid; Peptides; Phosphoprotein Phosphatases; Potassium Channels; Protein Phosphatase 2; Purinones; Rabbits; Scorpion Venoms | 1995 |
Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Pressure; Drug Synergism; Guanylate Cyclase; In Vitro Techniques; Male; Nitroglycerin; Nitroprusside; Phosphodiesterase Inhibitors; Purinones; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Vasodilation | 1994 |
Reversal of nitroglycerin tolerance in vitro by the cGMP-phosphodiesterase inhibitor zaprinast.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Cyclic GMP; Drug Tolerance; Hydrolysis; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitroglycerin; Purinones; Rats; Rats, Sprague-Dawley | 1993 |
Lack of cross-tolerance between nitroglycerin and endothelium-derived relaxing factor-mediated vasoactive agents in spontaneously hypertensive rats.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Animals; Arginine; Blood Pressure; Bradykinin; Drug Tolerance; Hypertension; Male; Nitric Oxide; Nitroarginine; Nitroglycerin; Purinones; Rats; Rats, Inbred SHR; Vasodilator Agents | 1993 |
Relationship between myoglobin contents and increases in cyclic GMP produced by glyceryl trinitrate and nitric oxide in rabbit aorta, right atrium and papillary muscle.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Atrial Function, Right; Cyclic GMP; Kinetics; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Myoglobin; Nitric Oxide; Nitroglycerin; Papillary Muscles; Purinones; Rabbits | 1993 |
Insulin exerts opposite effects on platelet function at physiological and supraphysiological concentrations.
Topics: Adenosine Diphosphate; Adult; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Insulin; Male; Nitroglycerin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinones; Theophylline; Vasodilator Agents | 1996 |
The potentiation of nitroglycerin-induced relaxation by PKG inhibition in rat aortic rings.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Male; Muscle, Smooth, Vascular; Naphthalenes; Nitroglycerin; Potassium Channels; Protein Kinase C; Purinones; Rats; Rats, Wistar; Staurosporine; Sulfonamides; Vasodilator Agents | 1996 |
Zaprinast, but not dipyridamole, reverses hemodynamic tolerance to nitroglycerin in vivo.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Analysis of Variance; Animals; Aorta, Abdominal; Blood Pressure; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Tolerance; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Purinones; Rats; Rats, Inbred SHR; Vasodilator Agents | 1996 |
Cardiovascular activity of WIN 65579, a novel inhibitor of cyclic GMP phosphodiesterase 5.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Blood Pressure; Cyclic GMP; Heart Rate; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Phosphodiesterase Inhibitors; Purinones; Pyrimidines; Rats; Rats, Inbred SHR | 1998 |
Differential sensitivity among nitric oxide donors toward ODQ-mediated inhibition of vascular relaxation.
Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Interactions; Guanylate Cyclase; Male; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Oxadiazoles; Penicillamine; Phosphodiesterase Inhibitors; Purinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2000 |
Phosphodiesterase inhibitor-mediated potentiation of adenovirus delivery to myocardium.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenoviruses, Human; Animals; beta-Galactosidase; Cyclic GMP; Drug Synergism; Endothelial Growth Factors; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; Guanylate Cyclase; Heart; Humans; Isoquinolines; Lymphokines; Myocardium; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Piperazines; Purines; Purinones; Pyridines; Rabbits; Sildenafil Citrate; Sulfones; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Mechanisms underlying the hydrogen peroxide-induced, endothelium-independent relaxation of the norepinephrine-contraction in guinea-pig aorta.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Male; Methylene Blue; Myosin Light Chains; Nitroglycerin; Norepinephrine; Oxadiazoles; Phosphorylation; Purinones; Quinoxalines; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2003 |
Inhibition of phosphoinositide 3-kinase potentiates relaxation of porcine coronary arteries induced by nitroglycerin by decreasing phosphodiesterase type 5 activity.
Topics: Animals; Chromones; Coronary Vessels; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Enzyme Inhibitors; Milrinone; Models, Animal; Morpholines; Nifedipine; Nitroglycerin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Purinones; Signal Transduction; Swine; Vasodilation; Vasodilator Agents | 2012 |