nitrogen-dioxide has been researched along with nas* in 2 studies
2 other study(ies) available for nitrogen-dioxide and nas
| Article | Year |
|---|---|
Short-term air pollution and temperature exposure and changes in the extracellular microRNA profile of Normative Aging Study (NAS) participants.
While the health effects of air pollution and temperature are widely studied, the molecular effects are poorly understood. Extracellular microRNAs (ex-miRNAs) have the potential to serve as diagnostic or prognostic biomarkers and/or to act as intercellular signaling molecules that mediate the effects of environmental exposures on health outcomes.. We examined the relationship between short-term exposure to air pollution and ambient temperature and the ex-miRNA profiles of participants in the Normative Aging Study (NAS) from 1999 to 2015. Our exposures were defined as same-day, two-day, three-day, one-week, two-week, and three-week moving averages of PM. We found that all the examined exposures were associated with changes in ex-miRNA profiles in our study, particularly PM. Air pollution and temperature exposures were significantly associated with alterations in the ex-miRNA profiles of NAS subjects with possible biological consequences. Topics: Aging; Air Pollutants; Air Pollution; Environmental Exposure; Humans; MicroRNAs; Nitrogen Dioxide; Ozone; Particulate Matter; Temperature | 2023 |
Intermediate and long-term exposure to air pollution and temperature and the extracellular microRNA profile of participants in the normative aging study (NAS).
The molecular effects of intermediate and long-term exposure to air pollution and temperature, such as those on extracellular microRNA (ex-miRNA) are not well understood but may have clinical consequences.. To assess the association between exposure to ambient air pollution and temperature and ex-miRNA profiles.. Our study population consisted of 734 participants in the Normative Aging Study (NAS) between 1999 and 2015. We used high-resolution models to estimate four-week, eight-week, twelve-week, six-month, and one-year moving averages of PM. We found 151 significant associations between levels of PM. Our results show that intermediate and long-term exposure to all our exposures of interest were associated with changes in the ex-miRNA profile of study participants. Further studies on environmental risk factors and ex-miRNAs are warranted. Topics: Aging; Air Pollutants; Air Pollution; Environmental Exposure; Humans; MicroRNAs; Nitrogen Dioxide; Ozone; Particulate Matter; Temperature | 2023 |