nitrogen-dioxide has been researched along with 6-methyl-2-ethyl-3-hydroxypyridine* in 1 studies
1 other study(ies) available for nitrogen-dioxide and 6-methyl-2-ethyl-3-hydroxypyridine
| Article | Year |
|---|---|
[Modifying effect of nitrites on pulmonary blastogenesis and viral leukogenesis in mice: role of nitric oxide and dioxide].
The long-term effects of sodium nitrite (NaNO2) on carcinogenesis induced by urethane (total dose 1.0 mg/g body weight) in low-grade cancer F1 (C57BLxCBA) and high-grade A/Snell mice and on viral (Rausher leukemia virus) leukomogenesis in Balb/c mice. The murine intake of NaNO2 with water (50 mg/l) causes a statistically significant increase in the number of adenomas in the lung. Examining the mechanism of conversion of NO2- to NO led to the assumption that the free radical compounds NO and NO2 are involved in the potentiating action of NO2 on blastomogenesis. The use of the oxidant emoxypine (3-hydroxypyridine) confirmed the above. The role of NO and NO2 in the intracellular processes under the modifying effects of nitrites and nitrates on blastomogenesis is analyzed. Topics: Adenoma; Animals; Antioxidants; Carcinogenicity Tests; Female; Leukemia Virus, Murine; Leukocytes; Lung; Lung Neoplasms; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasms, Experimental; Nitric Oxide; Nitrites; Nitrogen Dioxide; Oxidants, Photochemical; Picolines | 2000 |