nitrofurantoin and methotrexate

nitrofurantoin has been researched along with methotrexate in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (24.24)	18.7374
1990's	1 (3.03)	18.2507
2000's	11 (33.33)	29.6817
2010's	13 (39.39)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Lippmann, M	1
Bermudez García, JM; Gil Extremera, B; Peña Yañez, A; Raya Muñóz, J; Suárez Pañeda, JR	1
Ward, MJ; White, JP	1
Sahn, SA	1
Rosenow, EC	1
Whitcomb, ME	1
Brettner, A; Heitzman, ER; Woodin, WG	1
Seeff, LB	1
Hanson, L	1
Huggins, JT; Sahn, SA	1
Bischoff, A	1
Gowarty, JL; Herrington, JD; Patel, IJ	1

Reviews

8 review(s) available for nitrofurantoin and methotrexate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Pulmonary reactions to drugs. The Medical clinics of North America, 1977, Volume: 61, Issue:6 Topics: Adrenal Cortex Hormones; Aged; Aminoglycosides; Bleomycin; Busulfan; Contraceptives, Oral; Female; Foreign Bodies; Humans; Hypertension, Pulmonary; Lung; Lung Diseases; Mercury; Methotrexate; Nitrofurantoin; Paraquat; Phenytoin; Pneumonia; Polymyxins; Radiation Injuries; Sulfonamides	1977
Drug-induced adverse pulmonary reactions. Adverse drug reactions and acute poisoning reviews, 1985,Winter, Volume: 4, Issue:4 Topics: Amiodarone; Asthma; Bleomycin; Carmustine; Drug-Related Side Effects and Adverse Reactions; Gold; Humans; Hydrochlorothiazide; Hypertension, Pulmonary; Lung Diseases; Lupus Erythematosus, Systemic; Lymphatic Diseases; Mediastinum; Methotrexate; Nitrofurantoin; Penicillamine; Pleural Effusion; Pulmonary Edema; Pulmonary Eosinophilia; Pulmonary Fibrosis; Ritodrine	1985
Immunologic diseases of the pleura. Clinics in chest medicine, 1985, Volume: 6, Issue:1 Topics: Adult; Aged; Bromocriptine; Cardiac Surgical Procedures; Collagen Diseases; Dantrolene; Female; Granulomatosis with Polyangiitis; Heart Injuries; Humans; Immune System Diseases; Immunoblastic Lymphadenopathy; Lupus Erythematosus, Systemic; Male; Methotrexate; Methysergide; Middle Aged; Myocardial Infarction; Nitrofurantoin; Pacemaker, Artificial; Pleural Diseases; Pleural Effusion; Practolol; Procarbazine; Rheumatic Diseases; Sarcoidosis; Syndrome; Thoracic Injuries	1985
The spectrum of drug-induced pulmonary disease. Annals of internal medicine, 1972, Volume: 77, Issue:6 Topics: Adrenal Cortex Hormones; Aerosols; Analgesics; Aspirin; Autonomic Agents; Bleomycin; Busulfan; Contraceptives, Oral; Cyclophosphamide; Dextropropoxyphene; Drug Hypersensitivity; Heroin; Humans; Lung Diseases; Lupus Erythematosus, Systemic; Methadone; Methotrexate; Mineral Oil; Nitrofurantoin; Oxygen Inhalation Therapy; Paraquat; Pituitary Gland, Posterior; Pleural Effusion; Sulfonamides; Tissue Extracts	1972
Drug-induced lung disease. Chest, 1973, Volume: 63, Issue:3 Topics: Anti-Bacterial Agents; Anticoagulants; Antihypertensive Agents; Bleomycin; Busulfan; Chlorpropamide; Cyclophosphamide; Hemorrhage; Heroin; Humans; Hydrochlorothiazide; Hypertension, Pulmonary; Inhalation; Leukemia, Lymphoid; Lipids; Lung; Lung Diseases; Methotrexate; Methysergide; Nitrofurantoin; Phenytoin; Pulmonary Edema	1973
Drug-induced chronic liver disease, with emphasis on chronic active hepatitis. Seminars in liver disease, 1981, Volume: 1, Issue:2 Topics: Biopsy; Chemical and Drug Induced Liver Injury; Chlorpromazine; Dantrolene; Diagnosis, Differential; Fat Necrosis; Female; Hepatitis, Viral, Human; Humans; Liver Cirrhosis, Biliary; Male; Methotrexate; Methyldopa; Middle Aged; Nitrofurantoin; Oxyphenisatin Acetate; Perhexiline	1981
Drug-induced pleural disease. Clinics in chest medicine, 2004, Volume: 25, Issue:1 Topics: Anti-Infective Agents, Urinary; Antimetabolites, Antineoplastic; Bleomycin; Cardiovascular Agents; Clozapine; Cyclophosphamide; Eosinophilia; Humans; Immunosuppressive Agents; Interleukin-2; Methotrexate; Methysergide; Nitrofurantoin; Penicillamine; Pleural Diseases; Pleural Effusion; Serotonin Antagonists	2004

Trials

1 trial(s) available for nitrofurantoin and methotrexate

Article	Year
[A case of idiopathic transverse acute myelopathy with a favorable response to intravenous methotrexate associated to corticoids]. Revista clinica espanola, 1978, Jan-15, Volume: 148, Issue:1 Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Hemiplegia; Humans; Injections, Intravenous; Male; Methotrexate; Methylprednisolone; Nitrofurantoin; Spinal Cord Diseases; Tablets	1978

Article

Year

[A case of idiopathic transverse acute myelopathy with a favorable response to intravenous methotrexate associated to corticoids].

Revista clinica espanola, 1978, Jan-15, Volume: 148, Issue:1

Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Hemiplegia; Humans; Injections, Intravenous; Male; Methotrexate; Methylprednisolone; Nitrofurantoin; Spinal Cord Diseases; Tablets

1978

Other Studies

24 other study(ies) available for nitrofurantoin and methotrexate

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids. Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20 Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Pulmonary complications of drug therapy. Radiology, 1970, Volume: 96, Issue:1 Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Busulfan; Child; Drug-Related Side Effects and Adverse Reactions; Female; Hexamethonium Compounds; Humans; Hydrochlorothiazide; Lung Diseases; Male; Mecamylamine; Methotrexate; Methysergide; Middle Aged; Nitrofurantoin; Penicillins; Phenytoin; Pleural Effusion; Pneumonia, Pneumocystis; Procainamide; Pulmonary Edema; Pulmonary Fibrosis; Radiography; Sulfadimethoxine	1970
Diffuse pulmonary infiltrates in a middle-aged woman. Journal of the Tennessee Medical Association, 1994, Volume: 87, Issue:2 Topics: Female; Humans; Lung; Methotrexate; Middle Aged; Nitrofurantoin; Pneumonia	1994
Drug-induced interstitial pneumonia. Prescrire international, 2008, Volume: 17, Issue:94 Topics: Amiodarone; Cytotoxins; Drug-Related Side Effects and Adverse Reactions; Humans; Imidazolidines; Lung; Lung Diseases, Interstitial; Methotrexate; Nitrofurantoin; Paraffin; Protein-Tyrosine Kinases; Pulmonary Fibrosis	2008
[Toxic effects on the lung: is "pneumonia" caused by drugs?]. MMW Fortschritte der Medizin, 2009, Jun-25, Volume: 151, Issue:26-29 Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-Infective Agents, Urinary; Antibiotics, Antineoplastic; Antirheumatic Agents; Bleomycin; Drug-Related Side Effects and Adverse Reactions; Humans; Lung; Lung Diseases; Methotrexate; Nitrofurantoin; Radiography, Thoracic; Risk Factors; Time Factors; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha	2009
Altered methotrexate clearance in the treatment of CNS lymphoma with concurrent use of nitrofurantoin for a urinary tract infection. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:7 Topics: Aged; Central Nervous System Neoplasms; Drug Interactions; Female; Humans; Lymphoma, Non-Hodgkin; Methotrexate; Nitrofurantoin; Urinary Tract Infections	2019