Page last updated: 2024-09-03

nitroflurbiprofen and aspirin

nitroflurbiprofen has been researched along with aspirin in 9 studies

Compound Research Comparison

Studies
(nitroflurbiprofen)
Trials
(nitroflurbiprofen)
Recent Studies (post-2010)
(nitroflurbiprofen)
Studies
(aspirin)
Trials
(aspirin)
Recent Studies (post-2010) (aspirin)
581648,9476,81713,778

Protein Interaction Comparison

ProteinTaxonomynitroflurbiprofen (IC50)aspirin (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.35
Integrin beta-3Homo sapiens (human)5
Prostaglandin G/H synthase 1Ovis aries (sheep)0.8252
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)1.375
Integrin alpha-IIbHomo sapiens (human)5
Prostaglandin G/H synthase 1Homo sapiens (human)2.271
Substance-P receptorCavia porcellus (domestic guinea pig)2.4
Prostaglandin G/H synthase 2Homo sapiens (human)2.15
Urotensin-2 receptorRattus norvegicus (Norway rat)0.3
4-aminobutyrate aminotransferase, mitochondrialRattus norvegicus (Norway rat)2.4
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.35
Prostaglandin G/H synthase 2Ovis aries (sheep)2.4081

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's7 (77.78)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Antonelli, E; Cirino, G; Coata, G; Distrutti, E; Federici, B; Fiorucci, S; Morelli, A; Morelli, O; Renzo, GD; Santucci, L; Soldato, PD1
Al-Swayeh, OA; Keeble, J; Moore, PK1
Beckman, M1
Butcher, C; Evans, CE1
Breese, E; Del Soldato, P; Mitchell, J; Warner, T; Wood, E; Zacharowski, P1
Astle, CM; Floyd, RA; Flurkey, K; Harrison, DE; Hensley, KL; Javors, MA; Leeuwenburgh, C; Miller, RA; Nadon, NL; Nelson, JF; Ongini, E; Strong, R; Warner, HR2
Ji, H; Peng, SX; Zhang, YH1
Astle, CM; Flurkey, K; Harrison, DE1

Reviews

1 review(s) available for nitroflurbiprofen and aspirin

ArticleYear
[A novel class of anti-inflammatory and analgesic drugs--NO-donating NSAIDs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2007, Volume: 42, Issue:4

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiotonic Agents; Cyclooxygenase Inhibitors; Flurbiprofen; Gastrointestinal Diseases; Humans; Ibuprofen; Naproxen; Nitrates; Nitric Oxide Donors

2007

Other Studies

8 other study(ies) available for nitroflurbiprofen and aspirin

ArticleYear
Nitric oxide-releasing NSAIDs inhibit interleukin-1beta converting enzyme-like cysteine proteases and protect endothelial cells from apoptosis induced by TNFalpha.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase Inhibitors; Cell Line; Cysteine Proteinase Inhibitors; DNA Fragmentation; Endothelium, Vascular; Flurbiprofen; Gastric Mucosa; Humans; In Situ Nick-End Labeling; Male; Mice; Naproxen; Nitric Oxide; Peroxidase; Rats; Rats, Wistar

1999
Vasorelaxant effect of nitric oxide releasing steroidal and nonsteroidal anti-inflammatory drugs.
    British journal of pharmacology, 2001, Volume: 133, Issue:7

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Blood Pressure; Dose-Response Relationship, Drug; Flurbiprofen; In Vitro Techniques; Kidney; Male; Mesentery; Nitric Oxide; Nitroprusside; Prednisolone; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents

2001
Placing bets. National Institute on Aging committee chooses three compounds for definitive longevity testing.
    Science of aging knowledge environment : SAGE KE, 2004, Feb-04, Volume: 2004, Issue:5

    Topics: Aging; Animals; Aspirin; Flurbiprofen; Longevity; Mice; National Institutes of Health (U.S.); United States

2004
The influence on human osteoblasts in vitro of non-steroidal anti-inflammatory drugs which act on different cyclooxygenase enzymes.
    The Journal of bone and joint surgery. British volume, 2004, Volume: 86, Issue:3

    Topics: Acetaminophen; Alkaline Phosphatase; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Count; Cells, Cultured; Collagen; Cyclooxygenase Inhibitors; DNA; Flurbiprofen; Furans; Humans; Indomethacin; Nitrates; Nitric Oxide; Nitric Oxide Donors; Osteoblasts; Prostaglandin-Endoperoxide Synthases

2004
NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives.
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Membrane Proteins; Naproxen; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Purinones; Synovial Membrane; Time Factors

2005
An Aging Interventions Testing Program: study design and interim report.
    Aging cell, 2007, Volume: 6, Issue:4

    Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Cyclic N-Oxides; Drug Evaluation, Preclinical; Female; Flurbiprofen; Male; Masoprocol; Mice; Research Design; Survival Analysis

2007
Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice.
    Aging cell, 2008, Volume: 7, Issue:5

    Topics: Animals; Aspirin; Cyclic N-Oxides; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Free Radical Scavengers; Genetic Heterogeneity; Lipoxygenase Inhibitors; Longevity; Male; Masoprocol; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Random Allocation; Sex Characteristics; Survival Analysis

2008
Life extension by diet restriction and N-acetyl-L-cysteine in genetically heterogeneous mice.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2010, Volume: 65, Issue:12

    Topics: Acetylcysteine; Animals; Aspirin; Crosses, Genetic; Diet; Female; Flurbiprofen; Imines; Life Expectancy; Longevity; Male; Masoprocol; Mice; Mice, Inbred Strains; Phenols; Sex Factors

2010