Compounds > nitrofenac
Page last updated: 2024-09-04

nitrofenac and diclofenac

nitrofenac has been researched along with diclofenac in 7 studies

Compound Research Comparison

Studies
(nitrofenac)		Trials
(nitrofenac)		Recent Studies (post-2010)
(nitrofenac)		Studies
(diclofenac)		Trials
(diclofenac)		Recent Studies (post-2010) (diclofenac)
8008,8741,8743,616

Protein Interaction Comparison

ProteinTaxonomynitrofenac (IC50)diclofenac (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)1.9
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.003
Prostaglandin G/H synthase 1Ovis aries (sheep)1.3376
Interleukin-8Homo sapiens (human)0.008
Prostaglandin G/H synthase 1Homo sapiens (human)0.0415
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.5
C-X-C chemokine receptor type 1Homo sapiens (human)0.012
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Homo sapiens (human)0.4165
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Ovis aries (sheep)1.6867
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.0502
Solute carrier family 22 member 6Homo sapiens (human)4
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.02

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cirino, G; Pittman, QJ; Wallace, JL1
Cirino, G; Elliott, SN; McKnight, W; Wallace, JL1
Adami, A; Benoni, G; Cuzzolin, L; Del Soldato, P; Grigolini, L; Terzi, M1
Cirino, G; Reuter, BK; Wallace, JL1
Benoni, G; Brocco, G; Conforti, A; Cuzzolin, L; Del Soldato, P; Donini, M1
Cicala, C; Cirino, G; Grisham, M; McKnight, W; Reuter, B; Wallace, JL1
Davies, NM; Reuter, BK; Wallace, JL1

Other Studies

7 other study(ies) available for nitrofenac and diclofenac

ArticleYear
Nitric oxide-releasing NSAIDs: a novel class of GI-sparing anti-inflammatory drugs.
    Agents and actions. Supplements, 1995, Volume: 46

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Digestive System; Fibrinolytic Agents; Male; Nitric Oxide; Platelet Aggregation Inhibitors; Rats; Rats, Wistar

1995
A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats.
    Gastroenterology, 1995, Volume: 109, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cyclooxygenase Inhibitors; Diclofenac; Gastric Acid; Hematocrit; Male; Misoprostol; Rats; Rats, Wistar; Stomach Ulcer; Thromboxane B2

1995
Plasma concentrations and pharmacokinetic parameters of nitrofenac using a simple and sensitive HPLC method.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Hydrogen-Ion Concentration; Indicators and Reagents; Male; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet

1995
Markedly reduced intestinal toxicity of a diclofenac derivative.
    Life sciences, 1994, Volume: 55, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Diclofenac; Dose-Response Relationship, Drug; Drug Administration Schedule; Intestines; Male; Rats; Rats, Wistar

1994
Acute anti-inflammatory activity and gastrointestinal tolerability of diclofenac and nitrofenac.
    Agents and actions, 1993, Volume: 40, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Edema; Female; Gastrointestinal Diseases; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1993
A diclofenac derivative without ulcerogenic properties.
    European journal of pharmacology, 1994, May-23, Volume: 257, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Diclofenac; Gastric Mucosa; Inflammation; Male; Nitrates; Nitrites; Prostaglandins; Rabbits; Rats; Regional Blood Flow; Stomach; Stomach Ulcer

1994
Nonsteroidal anti-inflammatory drug enteropathy in rats: role of permeability, bacteria, and enterohepatic circulation.
    Gastroenterology, 1997, Volume: 112, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane Permeability; Colony Count, Microbial; Diclofenac; Enterohepatic Circulation; Intestinal Mucosa; Male; Rats; Rats, Wistar

1997