Page last updated: 2024-09-03

nitrobenzylthioinosine 5'-monophosphate and thioinosine

nitrobenzylthioinosine 5'-monophosphate has been researched along with thioinosine in 31 studies

Compound Research Comparison

Studies
(nitrobenzylthioinosine 5'-monophosphate)
Trials
(nitrobenzylthioinosine 5'-monophosphate)
Recent Studies (post-2010)
(nitrobenzylthioinosine 5'-monophosphate)
Studies
(thioinosine)
Trials
(thioinosine)
Recent Studies (post-2010) (thioinosine)
3201816877

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199014 (45.16)18.7374
1990's9 (29.03)18.2507
2000's6 (19.35)29.6817
2010's1 (3.23)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Adjei, AA; Dagnino, L; Paterson, AR; Wong, MM1
Gero, AM; Wood, AM1
el Kouni, MH1
Fincham, DA; Wolowyk, MW; Young, JD1
Gati, WP; Iwashina, T; Knaus, EE; McQueen, L; Wiebe, LI1
Carlisle, R; Diop, D; el Kouni, MH; O'Shea, P; Sommadossi, JP1
Knaus, EE; Wiebe, LI1
Cha, S; el Kouni, MH1
Cha, S; el Kouni, MH; Messier, NJ1
Mahony, WB; Zimmerman, TP1
Clanachan, AS; Henderson, JF; Jarvis, SM; Paterson, AR; Young, JD1
Cha, SM; el Kouni, MH; Knopf, PM1
Gati, WP; Ogbunude, PO; Paterson, AR1
Ikediobi, CO; Ogbunude, PO1
Chou, TC; Kolassa, N; Paterson, AR1
Erlichman, C; Vidgen, D1
Cha, S; Diop, D; el Kouni, MH1
Buzzell, GR; Jakobs, ES; Kolassa, N; Paterson, AR1
Lynch, TP; Paran, JH; Paterson, AR1
Anderson, CM; Parkinson, FE; Sitar, DS1
Allay, JA; Belt, JA; Blakley, RL; Sorrentino, BP; Spencer, HT; Wilkinson, SL1
Allay, JA; Ashmun, RA; Blakley, RL; Galipeau, J; Persons, DA; Riberdy, JM; Sorrentino, BP1
Geiger, JD; Greenway, SC; Parkinson, FE; Peeling, J; Shepel, PN; Zhang, YW1
Allay, JA; Blakley, RL; Galipeau, J; Sorrentino, BP1
Diers, MD; McIvor, RS; Wagner, JE; Warlick, CA1
Bakken, AH; Lai, Y; Lum, PY; Schneider, G; SenGupta, DJ; Shubochkina, E; Unadkat, JD1
Frandsen, JL; McIvor, RS; Sweeney, CL; Verfaillie, CM1
Agricola, B; Allay, JA; Bonifacino, A; Donahue, RE; Dunbar, CE; Lu, T; Metzger, ME; Persons, DA; Sorrentino, BP1
Aoki, JI; Cotrim, PC; Ramos, DC; Yamashiro-Kanashiro, EH1
Choi, DS; Choi, S; Kim, T; Lee, MR; Wu, J1
Cherrington, NJ; Galligan, JJ; Hau, RK; Jennings, EQ; Jilek, JL; McGrath, ME; Miller, SR; Wright, SH1

Other Studies

31 other study(ies) available for nitrobenzylthioinosine 5'-monophosphate and thioinosine

ArticleYear
Protection against fludarabine neurotoxicity in leukemic mice by the nucleoside transport inhibitor nitrobenzylthioinosine.
    Cancer chemotherapy and pharmacology, 1992, Volume: 31, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Female; Hindlimb; Leukemia L1210; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Nervous System Diseases; Paralysis; Prodrugs; Thioinosine; Thionucleotides; Vidarabine

1992
New nucleoside transport pathways induced in the host erythrocyte membrane of malaria and Babesia infected cells.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Adenosine; Animals; Babesia bovis; Babesiosis; Biological Transport; Cattle; Cattle Diseases; Dilazep; Drug Therapy, Combination; Erythrocyte Membrane; Erythrocytes; Malaria; Malaria, Falciparum; Mice; Plasmodium falciparum; Pyrimidine Nucleosides; Thioinosine; Thionucleotides; Tubercidin

1991
Efficacy of combination therapy with tubercidin and nitrobenzylthioinosine 5'-monophosphate against chronic and advanced stages of schistosomiasis.
    Biochemical pharmacology, 1991, Mar-01, Volume: 41, Issue:5

    Topics: Animals; Drug Therapy, Combination; Follow-Up Studies; Intestines; Life Expectancy; Liver; Mice; Schistosomiasis mansoni; Thioinosine; Thionucleotides; Tubercidin

1991
Nucleoside uptake by red blood cells from a primitive vertebrate, the Pacific hagfish (Eptatretus stouti), is mediated by a nitrobenzylthioinosine-insensitive transport system.
    Biochimica et biophysica acta, 1991, Oct-14, Volume: 1069, Issue:1

    Topics: Animals; Biological Transport; Erythrocytes; Hagfishes; Nucleosides; Thioinosine; Thionucleotides

1991
Drug-induced perturbations in the in vivo distribution of oncological radiotracers--II. 5-[125I]iodo-2'-deoxyuridine influenced by nitrobenzylthioinosine-5'-phosphate (NBMPR-P) and acyclothymidine (ACT).
    International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1990, Volume: 41, Issue:2

    Topics: Animals; Idoxuridine; Inosine; Iodine Radioisotopes; Lung Neoplasms; Male; Mice; Neoplasm Transplantation; Radionuclide Imaging; Stimulation, Chemical; Thioinosine; Thionucleotides; Tissue Distribution; Uracil

1990
Prevention of tubercidin host toxicity by nitrobenzylthioinosine 5'-monophosphate for the treatment of schistosomiasis.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Colony-Forming Units Assay; Female; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Inosine; Mice; Schistosomiasis; Thioinosine; Thionucleotides; Tubercidin

1989
Drug-induced perturbations in the in vivo distribution of oncological radiotracers--I. 5-Fluoro-6-3H-2'-deoxyuridine influenced by nitrobenzylthioinosine 5'-phosphate (NBMPR-P).
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1986, Volume: 13, Issue:3

    Topics: Animals; Floxuridine; Inosine; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Radionuclide Imaging; Thioinosine; Thionucleotides; Tissue Distribution; Tritium

1986
Metabolism of adenosine analogues by Schistosoma mansoni and the effect of nucleoside transport inhibitors.
    Biochemical pharmacology, 1987, Apr-01, Volume: 36, Issue:7

    Topics: Adenosine; Animals; Biological Transport; Dilazep; Dipyridamole; Kinetics; Nucleosides; Schistosoma mansoni; Structure-Activity Relationship; Thioinosine; Thionucleotides; Uracil

1987
Treatment of schistosomiasis by purine nucleoside analogues in combination with nucleoside transport inhibitors.
    Biochemical pharmacology, 1987, Nov-15, Volume: 36, Issue:22

    Topics: Adenosine; Animals; Biological Transport; Dilazep; Dipyridamole; Drug Therapy, Combination; Female; Mice; Purine Nucleosides; Ribonucleosides; Schistosoma mansoni; Schistosomiasis; Thioinosine; Thionucleotides; Toyocamycin; Tubercidin; Uracil

1987
An assay for inhibitors of nucleoside transport based upon the use of 5-[125I]iodo-2'-deoxyuridine as permeant.
    Analytical biochemistry, 1986, Volume: 154, Issue:1

    Topics: Adenosine; Biological Transport, Active; Erythrocytes; Humans; Idoxuridine; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Nucleosides; Thioinosine; Thionucleotides

1986
Nitrobenzylthioinosine: an in vivo inhibitor of pig erythrocyte energy metabolism.
    The American journal of physiology, 1986, Volume: 251, Issue:1 Pt 1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Blood Glucose; Energy Metabolism; Erythrocytes; Inosine; Swine; Thioinosine; Thionucleotides

1986
Combination therapy of Schistosoma japonicum by tubercidin and nitrobenzylthioinosine 5'-monophosphate.
    Biochemical pharmacology, 1985, Nov-01, Volume: 34, Issue:21

    Topics: Animals; Drug Therapy, Combination; Female; Inosine; Kidney; Mice; Mice, Inbred Strains; Ribonucleosides; Schistosomiasis japonica; Thioinosine; Thionucleotides; Tubercidin

1985
Dephosphorylation of nitrobenzylthioinosine 5'-monophosphate by ecto 5'-nucleotidase of HeLa cells.
    Biochemical pharmacology, 1984, Nov-15, Volume: 33, Issue:22

    Topics: 5'-Nucleotidase; Animals; Binding Sites; Cell Membrane; Erythrocytes; HeLa Cells; Humans; Inosine; Kinetics; Male; Mice; Nucleotidases; Protein Binding; Thioinosine; Thionucleotides; Uridine

1984
Effect of nitrobenzylthioinosinate on the toxicity of tubercidin and ethidium against Trypanosoma gambiense.
    Acta tropica, 1982, Volume: 39, Issue:3

    Topics: Animals; Drug Synergism; Drug Therapy, Combination; Ethidium; Inosine; Male; Mice; Ribonucleosides; Thioinosine; Thionucleotides; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tubercidin

1982
Modification by nitrobenzylthioinosine-5'-monophosphate of pseudoisocytidine pharmacokinetics in mice and rats through inhibition of membrane transport.
    Cancer treatment reports, 1983, Volume: 67, Issue:1

    Topics: Animals; Biological Transport; Cell Membrane; Cytidine; Inosine; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Nucleosides; Perfusion; Rats; RNA; Thioinosine; Thionucleotides

1983
Antitumor activity of N-phosphonacetyl-L-aspartic acid in combination with nitrobenzylthioinosine.
    Biochemical pharmacology, 1984, Oct-15, Volume: 33, Issue:20

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cell Line; Dose-Response Relationship, Drug; Female; Inosine; Melanoma; Mice; Mice, Inbred C57BL; Nucleosides; Organophosphorus Compounds; Phosphonoacetic Acid; Thioinosine; Thionucleotides

1984
Combination therapy of schistosomiasis by tubercidin and nitrobenzylthioinosine 5'-monophosphate.
    Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:21

    Topics: Animals; Biological Transport; Disease Models, Animal; Drug Therapy, Combination; Female; Inosine; Mice; Ribonucleosides; Schistosomiasis; Thioinosine; Thionucleotides; Tubercidin

1983
Manipulation of toxicity and tissue distribution of tubercidin in mice by nitrobenzylthioinosine 5'-monophosphate.
    Biochemical pharmacology, 1982, May-15, Volume: 31, Issue:10

    Topics: Animals; Female; Inosine; Kidney; Kinetics; Liver; Mice; Ribonucleosides; Thioinosine; Thionucleotides; Tissue Distribution; Tubercidin

1982
Therapy of mouse leukemia L1210 with combinations of nebularine and nitrobenzylthioinosine 5'-monophosphate.
    Cancer research, 1981, Volume: 41, Issue:2

    Topics: Animals; Biological Transport, Active; Drug Therapy, Combination; Inosine; Leukemia L1210; Mice; Purine Nucleosides; Ribonucleosides; Thioinosine; Thionucleotides

1981
Ability of nitrobenzylthioinosine to cross the blood-brain barrier in rats.
    Neuroscience letters, 1996, Nov-29, Volume: 219, Issue:3

    Topics: Animals; Binding, Competitive; Blood-Brain Barrier; Brain; Injections, Intraperitoneal; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Sucrose; Thioinosine; Thionucleotides

1996
Sensitization of hematopoietic stem and progenitor cells to trimetrexate using nucleoside transport inhibitors.
    Blood, 1997, Nov-01, Volume: 90, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Cell Death; Drug Resistance, Neoplasm; Female; Hematopoietic Stem Cells; Humans; Mice; Mice, Inbred C57BL; Thioinosine; Thionucleotides; Thymidine; Trimetrexate

1997
In vivo selection of retrovirally transduced hematopoietic stem cells.
    Nature medicine, 1998, Volume: 4, Issue:10

    Topics: Animals; Blood Cells; Drug Resistance; Female; Folic Acid Antagonists; Genes, Reporter; Genetic Therapy; Genetic Vectors; Hematopoietic Stem Cell Transplantation; Mice; Mice, Inbred C57BL; Retroviridae; Selection, Genetic; Tetrahydrofolate Dehydrogenase; Thioinosine; Thionucleotides; Transformation, Genetic; Trimetrexate

1998
Effects of nitrobenzylthioinosine on neuronal injury, adenosine levels, and adenosine receptor activity in rat forebrain ischemia.
    Journal of neurochemistry, 2000, Volume: 75, Issue:2

    Topics: Adenosine; Affinity Labels; Animals; Cerebral Ventricles; Gene Expression Regulation; Injections, Intraventricular; Ischemic Attack, Transient; Male; Neurons; Prodrugs; Prosencephalon; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reperfusion; Thioinosine; Thionucleotides; Transcription, Genetic; Tumor Necrosis Factor-alpha

2000
Retroviral vectors containing a variant dihydrofolate reductase gene for drug protection and in vivo selection of hematopoietic cells.
    Stem cells (Dayton, Ohio), 1998, Volume: 16 Suppl 1

    Topics: Adult; Amino Acid Substitution; Animals; Antigens, CD; Bone Marrow Cells; CD24 Antigen; Encephalomyocarditis virus; Female; Gene Transfer Techniques; Genes, Reporter; Genetic Therapy; Genetic Variation; Genetic Vectors; Harvey murine sarcoma virus; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Membrane Glycoproteins; Mice; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Thioinosine; Thionucleotides; Transfection; Trimetrexate

1998
In vivo selection of antifolate-resistant transgenic hematopoietic stem cells in a murine bone marrow transplant model.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:1

    Topics: Animals; Blotting, Southern; Bone Marrow Transplantation; Female; Folic Acid Antagonists; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Leukocyte Count; Mice; Mice, Transgenic; Spleen; Tetrahydrofolate Dehydrogenase; Thioinosine; Thionucleotides; Trimetrexate

2002
A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine.
    Biochemistry, 2002, Feb-05, Volume: 41, Issue:5

    Topics: Alanine; Animals; Biological Transport; Cell Line; Conserved Sequence; Dogs; Equilibrative Nucleoside Transporter 1; Genetic Vectors; Glycine; Guanosine; Humans; Inosine; Membrane Transport Modulators; Membrane Transport Proteins; Mutagenesis, Site-Directed; Point Mutation; Saccharomyces cerevisiae; Thioinosine; Thionucleotides; Transfection; Uridine

2002
Trimetrexate inhibits progression of the murine 32Dp210 model of chronic myeloid leukemia in animals expressing drug-resistant dihydrofolate reductase.
    Cancer research, 2003, Mar-15, Volume: 63, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Drug Synergism; Female; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Mice, Inbred C3H; Mice, Transgenic; Tetrahydrofolate Dehydrogenase; Thioinosine; Thionucleotides; Trimetrexate

2003
Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques that received transplants with hematopoietic stem cells expressing dihydrofolate reductase vectors.
    Blood, 2004, Feb-01, Volume: 103, Issue:3

    Topics: Animals; Drug Combinations; Drug Resistance; Genetic Therapy; Genetic Vectors; Glucuronates; Green Fluorescent Proteins; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Luminescent Proteins; Macaca mulatta; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Thioinosine; Thionucleotides; Transduction, Genetic; Trimetrexate

2004
Efficacy of the tubercidin antileishmania action associated with an inhibitor of the nucleoside transport.
    Parasitology research, 2009, Volume: 104, Issue:2

    Topics: Animals; Antiparasitic Agents; Cells, Cultured; Drug Therapy, Combination; Enzyme Inhibitors; Leishmania; Leishmaniasis; Macrophages; Mice; Mice, Inbred BALB C; Schistosoma mansoni; Thioinosine; Thionucleotides; Trypanosoma brucei gambiense; Tubercidin

2009
ENT1 regulates ethanol-sensitive EAAT2 expression and function in astrocytes.
    Alcoholism, clinical and experimental research, 2010, Volume: 34, Issue:6

    Topics: Animals; Astrocytes; Cell Line; Central Nervous System Depressants; Dose-Response Relationship, Drug; Equilibrative Nucleoside Transporter 1; Ethanol; Excitatory Amino Acid Transporter 2; Glutamic Acid; Mice; RNA, Small Interfering; Thioinosine; Thionucleotides; Time Factors

2010
Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Cells, Cultured; Clofarabine; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Humans; Lamivudine; Male; Rats, Sprague-Dawley; Telomerase; Testis; Thioinosine; Thionucleotides

2021