Page last updated: 2024-09-03

nitroaspirin and thromboxane b2

nitroaspirin has been researched along with thromboxane b2 in 9 studies

Compound Research Comparison

Studies
(nitroaspirin)
Trials
(nitroaspirin)
Recent Studies (post-2010)
(nitroaspirin)
Studies
(thromboxane b2)
Trials
(thromboxane b2)
Recent Studies (post-2010) (thromboxane b2)
127987,483715485

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's7 (77.78)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bonapace, S; Degan, M; Fontana, L; Gaino, S; Lechi, A; Lechi, C; Minuz, P; Tommasoli, R; Zuliani, V1
Degan, M; Gaino, S; Lechi, A; Meneguzzi, A; Minuz, P; Santonastaso, CL; Soldato, PD; Zuliani, V1
Del Soldato, P; Miller, AM; Wainwright, CL; Work, LM1
del Soldato, P; Fiorucci, S; Lechi, A; Mencarelli, A; Meneguzzi, A; Minuz, P; Morelli, A1
Del Soldato, P; Faccino, RM; Fiorucci, S; Gresele, P; Morelli, A; Santucci, L1
Berti, F; Del Soldato, P; Manfredi, B; Polvani, G; Rossoni, G1
del Soldato, P; Fiorucci, S; Lechi, A; Mencarelli, A; Meneguzzi, A; Minuz, P; Morelli, A; Renga, B1
Corazzi, L; Corazzi, T; Gresele, P; Leone, M; Maucci, R1
Cardona, F; Derhaschnig, U; Jilma, B; Marsik, C; Minuz, P; Schweeger-Exeli, I1

Trials

3 trial(s) available for nitroaspirin and thromboxane b2

ArticleYear
Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study.
    Gastroenterology, 2003, Volume: 124, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiotonic Agents; Digestive System; Double-Blind Method; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Pilot Projects; Placebos; Platelet Aggregation; Thromboxane B2

2003
Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans.
    Journal of the American College of Cardiology, 2004, Aug-04, Volume: 44, Issue:3

    Topics: Administration, Oral; Adult; Aspirin; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Duodenum; Flow Cytometry; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Monocytes; Platelet Activation; Platelet Aggregation Inhibitors; Reference Values; Single-Blind Method; Stomach; Thromboxane A2; Thromboxane B2

2004
Effects of aspirin and NO-aspirin (NCX 4016) on platelet function and coagulation in human endotoxemia.
    Platelets, 2010, Volume: 21, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation; Blood Platelets; Double-Blind Method; Endotoxemia; Endotoxins; Humans; Male; Platelet Activation; Thromboxane B2; Young Adult

2010

Other Studies

6 other study(ies) available for nitroaspirin and thromboxane b2

ArticleYear
In vitro study of the anti-aggregating activity of two nitroderivatives of acetylsalicylic acid.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1996, Volume: 7, Issue:2

    Topics: Arachidonic Acid; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thromboxane A2; Thromboxane B2

1996
NCX4016 (NO-Aspirin) has multiple inhibitory effects in LPS-stimulated human monocytes.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Aspirin; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinolytic Agents; Guanylate Cyclase; Humans; Interleukin-6; Lipopolysaccharides; Monocytes; Nitric Oxide; Oxadiazoles; Quinoxalines; Thromboplastin; Thromboxane B2; Tumor Necrosis Factor-alpha

2001
NCX4016 (NO-aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia/reperfusion in pigs.
    British journal of pharmacology, 2002, Volume: 135, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Aspirin; Coronary Disease; Endothelium, Vascular; Hemodynamics; Leukocytes; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Platelet Aggregation; Swine; Thromboxane B2; Ventricular Fibrillation

2002
NCX-4016 (NO-aspirin) inhibits lipopolysaccharide-induced tissue factor expression in vivo: role of nitric oxide.
    Circulation, 2002, 12-10, Volume: 106, Issue:24

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cyclooxygenase 2; Cysteine Proteinase Inhibitors; Drug Administration Schedule; Flow Cytometry; Gastric Mucosa; Interleukin-1; Isoenzymes; Isosorbide Dinitrate; Male; Monocytes; Nitric Oxide; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thromboplastin; Thromboxane B2; Tumor Necrosis Factor-alpha

2002
Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats.
    European journal of pharmacology, 2003, Sep-05, Volume: 477, Issue:1

    Topics: Animals; Arteries; Aspirin; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Nitrates; Nitric Oxide Donors; Nitrites; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tail; Thromboxane B2; Time Factors; Vasoconstriction

2003
Direct and irreversible inhibition of cyclooxygenase-1 by nitroaspirin (NCX 4016).
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:3

    Topics: Animals; Aspirin; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dialysis; Dinoprostone; Dose-Response Relationship, Drug; Hemostatics; Humans; Kinetics; Molecular Structure; Monocytes; Platelet Aggregation Inhibitors; Sheep; Spectrophotometry; Thrombin; Thromboxane B2; Time Factors

2005