Page last updated: 2024-09-03

nitroaspirin and ncx 4040

nitroaspirin has been researched along with ncx 4040 in 7 studies

Compound Research Comparison

Studies
(nitroaspirin)
Trials
(nitroaspirin)
Recent Studies (post-2010)
(nitroaspirin)
Studies
(ncx 4040)
Trials
(ncx 4040)
Recent Studies (post-2010) (ncx 4040)
1279824011

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bos, C; de Esch, IJ; Hulsman, N; Jongejan, A; Leurs, R; Medema, JP; Richel, D; Smit, MJ; Wijtmans, M1
Angelini, G; Jeremy, JY; Muzaffar, S; Shukla, N1
Amadori, D; Bolla, M; Brigliadori, G; Fabbri, F; Rosetti, M; Tesei, A; Ulivi, P; Vannini, I; Zoli, W1
Chandrasena, RE; Dunlap, T; Sinha, V; Thatcher, GR; Wang, Z1
Bobko, A; Bratasz, A; Ignarro, LJ; Khramtsov, VV; Kuppusamy, P; Selvendiran, K; Wasowicz, T1
Balint, B; Bufan, B; Colić, M; Mojsilović, S; Vasilijić, S; Vucević, D; Vucićević, D1
Delgadillo, D; Duarte, LF; Fernández-Ramires, R; Fernández-Soto, R; Jara, JA; Madariaga-Venegas, F; Molina-Berríos, A; Suarez, N; Urzúa, B1

Other Studies

7 other study(ies) available for nitroaspirin and ncx 4040

ArticleYear
Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin.
    Journal of medicinal chemistry, 2007, May-17, Volume: 50, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Indolequinones; Magnetic Resonance Spectroscopy; Nitric Oxide; Nitric Oxide Donors; Structure-Activity Relationship

2007
Nitroaspirins and morpholinosydnonimine but not aspirin inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells.
    Circulation, 2004, Aug-31, Volume: 110, Issue:9

    Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Evaluation, Preclinical; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Epoprostenol; Glycoproteins; Guanylate Cyclase; Interleukin-1; Lipopolysaccharides; Male; Molsidomine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Onium Compounds; Pulmonary Artery; Respiratory Distress Syndrome; Superoxides; Sus scrofa; Tumor Necrosis Factor-alpha

2004
Molecular characterization of cytotoxic and resistance mechanisms induced by NCX 4040, a novel NO-NSAID, in pancreatic cancer cell lines.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:8

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase 9; Cell Cycle; Cell Line, Tumor; Cytotoxins; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Nitric Oxide Donors; Nitro Compounds; Pancreatic Neoplasms; S-Nitroso-N-Acetylpenicillamine; Salicylates

2006
Quinone formation as a chemoprevention strategy for hybrid drugs: balancing cytotoxicity and cytoprotection.
    Chemical research in toxicology, 2007, Volume: 20, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Catalysis; Cell Line, Tumor; Cell Survival; Chemoprevention; Cytoprotection; Esterases; Glutathione; Liver; Luciferases; Metabolic Detoxication, Phase II; Mice; Models, Biological; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Nitro Compounds; Response Elements; Swine

2007
NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols.
    Journal of translational medicine, 2008, Feb-26, Volume: 6

    Topics: Animals; Antineoplastic Agents; Aspirin; Cell Line, Tumor; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Mice; Mice, Nude; Molecular Structure; Nitro Compounds; Ovarian Neoplasms; Sensitivity and Specificity; Statistics as Topic; Sulfhydryl Compounds; Xenograft Model Antitumor Assays

2008
Comparative effects of aspirin and NO-releasing aspirins on differentiation, maturation and function of human monocyte-derived dendritic cells in vitro.
    International immunopharmacology, 2009, Volume: 9, Issue:7-8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antigens, Differentiation; Apoptosis; Aspirin; Cell Differentiation; Cells, Cultured; Dendritic Cells; Down-Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-10; Interleukin-12 Subunit p40; Interleukin-4; Lipopolysaccharides; Lymphocyte Activation; Monocytes; Nitric Oxide; Nitro Compounds

2009
Characterization of a novel antibiofilm effect of nitric oxide-releasing aspirin (NCX-4040) on Candida albicans isolates from denture stomatitis patients.
    PloS one, 2017, Volume: 12, Issue:5

    Topics: Antifungal Agents; Aspirin; Bacterial Adhesion; Biofilms; Candida albicans; Dinoprostone; Drug Resistance, Fungal; Fluconazole; Free Radical Scavengers; Humans; Inhibitory Concentration 50; Microbial Viability; Nitro Compounds; Stomatitis, Denture

2017