Compounds > nitroaspirin
Page last updated: 2024-09-03

nitroaspirin and flurbiprofen

nitroaspirin has been researched along with flurbiprofen in 6 studies

Compound Research Comparison

Studies
(nitroaspirin)		Trials
(nitroaspirin)		Recent Studies (post-2010)
(nitroaspirin)		Studies
(flurbiprofen)		Trials
(flurbiprofen)		Recent Studies (post-2010) (flurbiprofen)
127982,072466575

Protein Interaction Comparison

ProteinTaxonomynitroaspirin (IC50)flurbiprofen (IC50)
Prostaglandin G/H synthase 1Ovis aries (sheep)0.1683
Prostaglandin G/H synthase 1Homo sapiens (human)0.6754
Prostaglandin G/H synthase 2Homo sapiens (human)0.574
Aldo-keto reductase family 1 member C3Homo sapiens (human)1.56
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.5
Solute carrier family 22 member 6Homo sapiens (human)1.5
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.17

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Antonelli, E; Cirino, G; Coata, G; Distrutti, E; Federici, B; Fiorucci, S; Morelli, A; Morelli, O; Renzo, GD; Santucci, L; Soldato, PD1
Al-Swayeh, OA; Keeble, J; Moore, PK1
Butcher, C; Evans, CE1
Breese, E; Del Soldato, P; Mitchell, J; Warner, T; Wood, E; Zacharowski, P1
Ji, H; Peng, SX; Zhang, YH1
Güç, MO; Iskit, AB; Sökmensüer, C; Ulu, N1

Reviews

1 review(s) available for nitroaspirin and flurbiprofen

ArticleYear
[A novel class of anti-inflammatory and analgesic drugs--NO-donating NSAIDs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2007, Volume: 42, Issue:4

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiotonic Agents; Cyclooxygenase Inhibitors; Flurbiprofen; Gastrointestinal Diseases; Humans; Ibuprofen; Naproxen; Nitrates; Nitric Oxide Donors

2007

Other Studies

5 other study(ies) available for nitroaspirin and flurbiprofen

ArticleYear
Nitric oxide-releasing NSAIDs inhibit interleukin-1beta converting enzyme-like cysteine proteases and protect endothelial cells from apoptosis induced by TNFalpha.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase Inhibitors; Cell Line; Cysteine Proteinase Inhibitors; DNA Fragmentation; Endothelium, Vascular; Flurbiprofen; Gastric Mucosa; Humans; In Situ Nick-End Labeling; Male; Mice; Naproxen; Nitric Oxide; Peroxidase; Rats; Rats, Wistar

1999
Vasorelaxant effect of nitric oxide releasing steroidal and nonsteroidal anti-inflammatory drugs.
    British journal of pharmacology, 2001, Volume: 133, Issue:7

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Blood Pressure; Dose-Response Relationship, Drug; Flurbiprofen; In Vitro Techniques; Kidney; Male; Mesentery; Nitric Oxide; Nitroprusside; Prednisolone; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents

2001
The influence on human osteoblasts in vitro of non-steroidal anti-inflammatory drugs which act on different cyclooxygenase enzymes.
    The Journal of bone and joint surgery. British volume, 2004, Volume: 86, Issue:3

    Topics: Acetaminophen; Alkaline Phosphatase; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Count; Cells, Cultured; Collagen; Cyclooxygenase Inhibitors; DNA; Flurbiprofen; Furans; Humans; Indomethacin; Nitrates; Nitric Oxide; Nitric Oxide Donors; Osteoblasts; Prostaglandin-Endoperoxide Synthases

2004
NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives.
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Membrane Proteins; Naproxen; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Purinones; Synovial Membrane; Time Factors

2005
The effects of aspirin, flurbiprofen, and NO-donating acetylsalicylic acid (NCX 4016) on mice models of endotoxic and septic shock.
    Turkish journal of medical sciences, 2015, Volume: 45, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Flurbiprofen; Liver; Male; Mice; Shock, Septic; Spleen; Treatment Outcome

2015