nitrites and hydroxyurea

nitrites has been researched along with hydroxyurea in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's2 (16.67)18.2507
2000's6 (50.00)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kwon, NS; Nathan, CF; Stuehr, DJ1
Madoc-Jones, H; Mauro, F1
Bell, RL; Brooks, CD; Huang, R; Hulkower, KI; Otis, ER; Pollock, JS; Walsh, RE1
Alcaraz, MJ; Guillén, MI; Vicente, AM1
Gladwin, MT; Jankowski, MA; Link, B; Nichols, JS; Ognibene, FP; Pannell, LK; Patel, DB; Pease-Fye, ME; Rodgers, GP; Schechter, AN; Shelhamer, JH1
Ballas, SK; Huang, J; Kim-Shapiro, DB; King, SB; Lockamy, VL; Shields, H1
Ballas, SK; Huang, J; Kim-Shapiro, DB; King, SB; Zou, Z1
King, SB1
Li, W; Lou, TF; Mackie, A; Pace, BS; Singh, M1
de Souza, JH; Elias, DB; Gonçalves, RP; Magalhães, HI1
Borges, VM; da Guarda, CC; Goncalves, MS; Pitanga, TN; Santana, SS; Santiago, RP; Zanette, DL1
Bloch, W; Cannas, G; Collins, B; Connes, P; Fort, R; Gauthier, A; Grau, M; Guillot, N; Hot, A; Joly, P; Martin, C; Nader, E; Poutrel, S; Renoux, C; Romana, M; Thevis, M; Walpurgis, K1

Reviews

1 review(s) available for nitrites and hydroxyurea

ArticleYear
Nitric oxide production from hydroxyurea.
    Free radical biology & medicine, 2004, Sep-15, Volume: 37, Issue:6

    Topics: Anemia, Sickle Cell; Free Radicals; Hemoglobins; Humans; Hydroxylamine; Hydroxyurea; Iron; Models, Chemical; Nitrates; Nitric Oxide; Nitrites; Oxygen; Peroxidase; Time Factors; Urease

2004

Trials

1 trial(s) available for nitrites and hydroxyurea

ArticleYear
Hydroxyurea therapy modulates sickle cell anemia red blood cell physiology: Impact on RBC deformability, oxidative stress, nitrite levels and nitric oxide synthase signalling pathway.
    Nitric oxide : biology and chemistry, 2018, 12-01, Volume: 81

    Topics: Adult; Anemia, Sickle Cell; Erythrocyte Deformability; Erythrocytes; Female; Humans; Hydroxyurea; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction

2018

Other Studies

10 other study(ies) available for nitrites and hydroxyurea

ArticleYear
Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.
    The Journal of experimental medicine, 1991, Oct-01, Volume: 174, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Copper; Copper Sulfate; Ferredoxins; Gas Chromatography-Mass Spectrometry; Hydroxyurea; Interferon-gamma; Kinetics; Leukemia L1210; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ribonucleotide Reductases

1991
Age responses of cultured mammalian cells to cytotoxic drugs.
    Cancer research, 1970, Volume: 30, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Benzocycloheptenes; Colchicine; Cricetinae; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Griseofulvin; HeLa Cells; Hydroxylamines; Hydroxyurea; Mechlorethamine; Mitosis; Naphthacenes; Nitrites; Novobiocin; Potassium; Puromycin; RNA; Sulfates; Sulfides; Uracil Mustard; Vinblastine; Vincristine

1970
Leukotrienes do not regulate nitric oxide production in RAW 264.7 macrophages.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 55, Issue:3

    Topics: Animals; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Hydroxyurea; Interferon-gamma; Leukotriene B4; Leukotrienes; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Second Messenger Systems; Toxicity Tests

1996
Modulation of haem oxygenase-1 expression by nitric oxide and leukotrienes in zymosan-activated macrophages.
    British journal of pharmacology, 2001, Volume: 133, Issue:6

    Topics: Amidines; Animals; Benzylamines; Cell Line; Chick Embryo; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroxyurea; Indomethacin; Isoenzymes; Leukotriene B4; Leukotriene C4; Leukotrienes; Macrophage Activation; Macrophages; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyrans; Quinolones; Sulfonamides; Time Factors; Transcription Factor AP-1; Zymosan

2001
Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease.
    British journal of haematology, 2002, Volume: 116, Issue:2

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Female; Glutathione; Hemoglobins; Humans; Hydroxyurea; Luminescent Measurements; Male; Nitrates; Nitric Oxide Donors; Nitrites; Vascular Cell Adhesion Molecule-1

2002
Urease enhances the formation of iron nitrosyl hemoglobin in the presence of hydroxyurea.
    Biochimica et biophysica acta, 2003, Jul-23, Volume: 1622, Issue:2

    Topics: Antisickling Agents; Blood; Electron Spin Resonance Spectroscopy; Hemoglobins; Humans; Hydroxyurea; Nitrates; Nitrites; Spectrophotometry; Urease

2003
Hydroxyurea analogues as kinetic and mechanistic probes of the nitric oxide producing reactions of hydroxyurea and oxyhemoglobin.
    Journal of medicinal chemistry, 2003, Aug-14, Volume: 46, Issue:17

    Topics: Electrochemistry; Electron Spin Resonance Spectroscopy; Glycated Hemoglobin; Hydroxyurea; Kinetics; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Oxyhemoglobins; Structure-Activity Relationship

2003
Hydroxyurea generates nitric oxide in human erythroid cells: mechanisms for gamma-globin gene activation.
    Experimental biology and medicine (Maywood, N.J.), 2009, Volume: 234, Issue:11

    Topics: Cyclic GMP; Erythroid Cells; Fetal Hemoglobin; gamma-Globins; Humans; Hydrogen Peroxide; Hydroxyurea; K562 Cells; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Signal Transduction; Stem Cells; Transcription, Genetic; Transcriptional Activation

2009
Study of correlation of nitrite levels with malonaldehyde and the prognosis of patients with sickle cell disease on hydroxyurea, Ceará-Brazil.
    Journal of clinical laboratory analysis, 2011, Volume: 25, Issue:5

    Topics: Adult; Anemia, Sickle Cell; Blood Transfusion; Brazil; Cohort Studies; Female; Humans; Hydroxyurea; Leg Ulcer; Malondialdehyde; Nitrites; Oxidative Stress; Prognosis

2011
Heme changes HIF-α, eNOS and nitrite production in HUVECs after simvastatin, HU, and ascorbic acid therapies.
    Microvascular research, 2016, Volume: 106

    Topics: Anemia, Sickle Cell; Ascorbic Acid; Cells, Cultured; Dose-Response Relationship, Drug; Heme; Human Umbilical Vein Endothelial Cells; Humans; Hydroxyurea; Hypoxia-Inducible Factor 1, alpha Subunit; Nitric Oxide Synthase Type III; Nitrites; Simvastatin

2016