nitrites and citrulline

nitrites has been researched along with citrulline in 152 studies

Research

Studies (152)

TimeframeStudies, this research(%)All Research%
pre-199010 (6.58)18.7374
1990's62 (40.79)18.2507
2000's53 (34.87)29.6817
2010's25 (16.45)24.3611
2020's2 (1.32)2.80

Authors

AuthorsStudies
Bult, H; Herman, AG; Jorens, PG; van Overveld, FJ; Vermeire, PA1
Hishikawa, K; Kato, R; Nakaki, T; Saruta, T; Suzuki, H1
Bult, H; Devreese, AM; Herman, AG; Jorens, PG; Marescau, B; Rosseneu, M1
Bassetti, S; Keist, R; Keller, R; Klauser, S; Mülsch, A1
Flaman, JM; Henry, Y; Lepoivre, M1
Baeblich, SE; Böhme, E; Klein, MM; Schmidt, HH; Zernikow, BC1
Adams, LB; Hibbs, JB; Krahenbuhl, JL; Taintor, RR1
Albina, JE; Caldwell, MD; Henry, WL; Mills, CD1
Hibbs, JB; Taintor, RR; Vavrin, Z1
Boudbid, H; Lepoivre, M; Petit, JF1
Marletta, MA; Tayeh, MA1
Billiar, TR; Curran, RD; Hofmann, K; Simmons, RL; West, MA1
Billiar, TR; Curran, RD; Ferrari, FK; Simmons, RL; Stuehr, DJ1
Iyengar, R; Marletta, MA; Stuehr, DJ1
Bentz, BG; Billiar, TR; Curran, RD; Simmons, RL; Stuehr, DJ; West, MA1
Amber, IJ; Hibbs, JB; Taintor, RR; Vavrin, Z1
Mirvish, SS1
Ali, AM1
Acimovic, S; Andel, H; Függer, R; Längle, F; Mühlbacher, F; Roth, R; Steininger, R; Winkler, S1
Massoud, R; Mollace, V; Nistico, G; Rodino, P; Rotiroti, D1
Byam-Smith, M; Garfield, RE; Izumi, H; Yallampalli, C1
Adcock, IM; Buttery, LD; Kwon, OJ; Moncada, S; Polak, J; Riveros-Moreno, V; Robbins, RA; Springall, DR; Warren, JB; Wilson, AJ1
Beasley, D; Eldridge, M1
Hevel, JM; Marletta, MA1
Absood, A; Berisha, HI; Pakbaz, H; Said, SI1
Marletta, MA; Pufahl, RA; Wishnok, JS1
Chen, LY; Kone, BC; Mehta, JL; Mehta, P; Turner, P1
Mühl, H; Pfeilschifter, J1
Bucher, B; Busse, R; Hecker, M; Schott, C; Stoclet, JC1
Conte, A; Ottaviani, E1
Bosia, A; Bussolino, F; Costamagna, C; Deharo, E; Gabrielli, G; Gautret, P; Ghigo, D; Ginsburg, H; Giribaldi, G; Pescarmona, G; Todde, R; Ulliers, D1
Hey, C; Racké, K; Wessler, I1
Ganguly, NK; Jindal, SK; Kumar, V1
Kolb, H; Kolb-Bachofen, V; Kröncke, KD; Rodriguez, ML1
Adam, A; Sarih, M; Souvannavong, V1
Corbett, JA; Currie, MG; Kasten, TP; McDaniel, ML; Misko, TP; Moore, WM; Nickols, GA; Tilton, RG; Williamson, JR1
Lemaire, G; Petit, JF; Raddassi, K1
Damoulis, PD; Hauschka, PV1
Aihara, T; Ikeda, Y; Koyama, Y; Kusano, T; Muto, Y; Shiraishi, M1
Conte, A; Franchini, A; Ottaviani, E1
Dubois, G1
Thiemermann, C; Wu, CC1
Asahi, M; Fujii, J; Fujiwara, N; Kaneto, H; Seo, HG; Taniguchi, N1
Bult, H; Herman, AG; Jorens, PG; Marescau, B; Matthys, KE; Rosseneu, M; Van Hove, CE1
Ajami, AM; Beaumier, L; Castillo, L; Young, VR1
Agnihotri, N; Deodhar, SD; Ganguly, NK; Wanchu, A1
Araujo, HM; Assreuy, J; Fernandes, PD; Riveros-Moreno, V1
Briscini, L; Carruba, MO; Nisoli, E; Tonello, C1
Chaudhuri, G; Ignarro, LJ; Pervin, S; Rogers, NE; Singh, R1
Ganguli, NK; Gupta, I; Pradhan, M1
Higa, T; Hiroyasu, S; Kusano, T; Miyaguni, T; Muto, Y; Nagahama, M; Okuhama, Y; Shiraishi, M; Tomori, H1
Abramson, SB; Amin, AR; Attur, MG; Lowenstein, CJ; Patel, RN; Thakker, GD1
Dubey, RK; Fink, D; Imthurn, B; Keller, PJ; Lauper, U; Macas, E; Rosselli, M; Rosselli, MA1
Locher, R; Suter, PM; Vetter, W; Weisser, B1
Barbul, A; Schäffer, MR; Tantry, U; van Wesep, RA1
Chou, TC; Ding, YA; Ho, ST; Li, CY; Wong, CS; Wu, CC; Yen, MH1
Facchinetti, F; Marietta, M; Neri, I; Piccinini, F; Torelli, G; Volpe, A1
Bansal, MP; Kang, BP; Mehta, U1
Boucher, JL; Mansuy, D; Moali, C; Sari, MA; Stuehr, DJ1
Bina, S; Hart, JL; Muldoon, SM; Sei, Y1
Barthlen, W; Beger, HG; Brückner, UB; Marzinzig, E; Marzinzig, M; Morris, SM; Nussler, AK; Nussler, NC; Stadler, J1
Chouaib, S; Dugas, B; Dugas, N; Kolb, JP; Salvucci, O1
Bambery, P; Deodhar, SD; Khullar, M; Sud, A; Wanchu, A1
Feinstein, DL; Regunathan, S; Reis, DJ1
Houdijk, AP; Prins, HA; Teerlink, T; Thijs, LG; van Lambalgen, AA; van Leeuwen, PA; Wiezer, MJ1
Dees, WL; Hiney, JK; Rettori, V; Srivastava, VK1
Baylis, C; Schmidt, RJ; Sorkin, MI; Tracy, TS; Yokota, S1
Ganguly, NK; Gupta, I; Gupta, SK1
Weiske, J; Wiesner, A1
Holm, P; Kankaanranta, H; Knowles, RG; Moilanen, E; Oja, SS1
Folkerts, G; Hammermann, R; Hey, C; Hirschmann, J; Mössner, J; Nijkamp, FP; Racké, K; Wessler, I1
Bambery, P; Khullar, M; Sud, A; Wanchu, A2
Boggs, S; Huang, L; Stuehr, DJ1
Boulmerka, A; D'Alessio, P; D'Anna, R; Dugas, B; Geromin, D; Kolb, JP; Marconi, A; Marsac, C; Zadeh, MS1
Chen, PF; Wu, KK2
Aberle, S; Harvey, SE; Polokoff, MA; Rubanyi, GM; Zöllner, S1
Colasanti, M; Musci, G; Persichini, T; Polticelli, F; Venturini, G1
Bambery, P; Bhatnagar, A; Khullar, M; Singh, S; Sud, A; Wanchu, A2
Han, JW; Kim, SH; Lee, BG; Lee, HW; Lee, HY; Lee, KR; Zee, OP1
Meulemans, A2
Lepore, DA1
Gourdon, I; Guérin, MC; Roch, P; Torreilles, J1
Fraser, T; Li, M; Turner, SW; Wang, J; Wen, C; Whitworth, JA1
Hrabák, A; Kahán, IL; Vercruysse, V; Vray, B1
Devaux, Y; Grosjean, S; Kelly, RA; Meistelman, C; Mertes, PM; Seguin, C; Ungureanu-Longrois, D; Zannad, F1
Dikshit, M; Raghavan, SA1
Bayne, E; Duckworth, LJ; Freeman, B; Kissoon, N; Lima, JJ; Sandler, E; Sullivan, KJ; Sylvester, JE1
González-Santiago, L; López-Ongil, S; Rodríguez-Puyol, D; Rodríguez-Puyol, M1
Bergamini, S; Daneri, F; Iannone, A; Rota, C; Tomasi, A; Virgili, F1
Barthwal, MK; Dikshit, M; Sharma, P1
Cedergren, J; Forslund, T; Skogh, T; Sundqvist, T1
Leza, JC; Lizasoaín, I; Manzanares, J; Molina, JA; Moro, MA; Oliva, JM; Ortiz, S; Pérez, S; Urigüen, L1
Deutz, NE; Luiking, YC1
Aldieri, E; Bosia, A; Favini, R; Ghigo, D; Massobrio, M; Revelli, A1
Cuzzocrea, S; Ischiropoulos, H; Salvemini, D1
Antonaci, F; Costa, A; Nappi, G; Pucci, E; Ravaglia, S; Sances, G1
Endo, T; Hara, S; Kuriiwa, F; Kurosaki, K; Mukai, T1
Dikshit, M; Raghavan, SA; Sharma, P1
Franke, J; Gasslander, T; Sandstrom, P; Sundqvist, T; Svanvik, J1
Abu-Soud, HM; Diamond, MP; Galijasevic, S; Saed, GM1
Bhattacharyya, S; Ganguly, NK; Ghosh, S; Majumdar, S; Shant, J1
Acosta, F; Díaz, R; Ellis, AE; Gómez, V; Padilla, D; Real, F; Ruiz de Galarreta, CM1
Selley, ML1
Arranz, C; Balaszczuk, AM; Costa, MA; Elesgaray, R; Loria, A2
Alving, K; Bergström, J; Marteus, H; Mavropoulos, A; Palm, JP; Ulfgren, AK1
Boudko, D; Dahlgren, RL; Lovell, P; Moroz, LL; Sweedler, JV1
Bachmann, C; Boulat, O; Carrozzo, R; Dionisi-Vici, C; Emma, F; Mannucci, L; Markert, M; Rizzoni, G1
Govindasamy, C; Nadiger, HA; Sirajudeen, KN; Swamy, M; Zakaria, AZ1
Fukatsu, A; Funami, J; Hayashi, T; Ignarro, LJ; Iguchi, A; Juliet, PA; Matsui-Hirai, H; Miyazaki, A1
Deutz, NE; Diederen, RM; Hendrikse, F; Kessels, AG; La Heij, EC; van Eijk, HM1
Aguiló, A; Córdova, A; Fuentespina, E; Pons, A; Sureda, A; Tauler, P; Tur, JA1
Boeckx, WD; Booi, D; Buurman, WA; Debats, IB; Deutz, NE; van der Hulst, RR1
Espey, MG; Harvey-White, J; Jung, CS; Oldfield, EH; Pluta, RM; Seifert, V; Zimmermann, M1
Gross, SS; Weissman, BA1
Hovorková, P; Klaschka, J; Kozmiková, I; Kristofiková, Z; Majer, E; Rícný, J; Rípová, D; Zach, P1
Bannink, M; Eggermont, AM; Fekkes, D; Hengeveld, MW; Kruit, WH; Sleijfer, S; Stoter, G; van der Holt, B; Van Gool, AR1
Cordova, A; Ferrer, MD; Perez, G; Pons, A; Sureda, A; Tauler, P; Tur, JA1
Chandran, G; Sirajudeen, KN; Swamy, M1
Besson-Bard, A; Courtois, C; Dahan, J; Dobrowolska, G; Gauthier, A; Jeandroz, S; Pugin, A; Wendehenne, D1
Annie-Jeyachristy, S; Geetha, A; Kumar, SJ; Lavanya, K; Prakash, SA; Sundaram, A; Surendran, R1
Felipo, V; Llansola, M1
Córdova, A; Ferrer, MD; Pérez, G; Pons, A; Sureda, A; Tur, JA1
Brown, M; Duckworth, L; Froyen, M; Gauger, C; Kissoon, N; Murphy, S; Sandler, E; Sullivan, KJ1
de Hoon, JN; Depré, M; Van der Schueren, BJ; Van Hecken, A; Verbesselt, R; Verbrugge, FH1
Mittal, N; Sanyal, SN1
Fung, HL; Mohan, S; Shin, S; Wu, CC1
Bourdon, A; Darmaun, D; Des Robert, C; Legrand, A; Piloquet, H; Rougé, C; Rozé, JC; Vodovar, M; Voyer, M1
Amabile, N; Cortese-Krott, MM; Heiss, C; Horn, P; Hundsdörfer, C; Kelm, M; Kröncke, KD1
Spasić, S; Tomić, A; Zunić, G1
Boehm, M; Cortese-Krott, MM; Gladwin, MT; Kato, GJ; Kelm, M; Kovacic, JC; Liu, VB; Noguchi, A; Raghavachari, N; Wang, X; Wood, KC1
Busanello, EN; Grings, M; Leipnitz, G; Moura, AP; Tonin, AM; Viegas, CM; Wajner, M; Zanatta, A1
García-García, N; Hernández-Muñoz, R; Méndez-Rodríguez, ML; Olguín-Martínez, M; Quintana-Quintana, M; Ramírez-Zamora, S; Sánchez-Sevilla, L1
Hernández-Espinosa, DR; Hernández-Muñoz, R; Olguín-Martínez, M1
Borniquel, S; Carlström, M; Hezel, M; Huang, L; Kishikawa, H; Liu, M; Lundberg, JO; Peleli, M; Persson, AE; Weitzberg, E; Yang, T; Zollbrecht, C1
Briedé, JJ; Buurman, WA; de Winther, MP; Ghosh, M; Hoeksema, MA; Köhler, SE; Lamers, WH; Meesters, DM; Molin, DG; Poeze, M; van den Akker, NM; van Zandvoort, MA; Wijnands, KA1
Awad, AS; Cooper, TK; Gao, T; Morris, SM; You, H1
Eriksson, K; Larsson, AC; Lindholm, P; Nihlén, C; Schiffer, T; Uusijärvi, J; Weitzberg, E1
Andre, T; McKinley-Barnard, S; Morita, M; Willoughby, DS1
Bhargava, K; Bhaumik, G; Gangwar, A; Himashree, G; Padhy, G; Sethy, NK; Sharma, M; Singh, K1
Aranda Fraustro, A; Guarner Lans, V; Iturriaga Hernández, AV; Pérez-Torres, I; Soto, ME; Velázquez Espejel, R; Zuñiga-Muñoz, A1
Akopova, O; Gavenauskas, B; Kolchinskaya, L; Korkach, Y; Kotsiuruba, A; Mankovska, I; Nosar, V; Sagach, V; Serebrovska, Z1
Bailey, SJ; Blackwell, JR; Jones, AM; Vanhatalo, A; Williams, E; Winyard, PG; Wylie, LJ1
Kolpakov, IY; Kondrashova, VH; Kryzhanivska, VV; Leonovich, OS; Stepanova, YI; Vdovenko, VY; Zygalo, VM1
Abraham, A; Artaza, JN; Ferrini, MG; Flores, M; Graciano, L; Luna, R; Nguyen, S; Rajfer, J1
Keith, DS; Persky, AM; Ryan, ED; Schwartz, TA; Smith-Ryan, AE; Stoner, L; Trexler, ET1
Azizi, S; Ebrahimi-Mameghani, M; Karamzad, N; Mahdavi, R; Mobasseri, M1
Beckmann, B; Blau, LS; Dimina, L; Finkel, A; Jantz, M; Lützow, M; Maassen, N; Mariotti, F; Röhrig, MA; Shushakov, V; Thorns, A; Tsikas, D1

Reviews

5 review(s) available for nitrites and citrulline

ArticleYear
Nitric oxide: an ancestral immunocyte effector molecule.
    Advances in neuroimmunology, 1995, Volume: 5, Issue:4

    Topics: Animals; Cardiovascular Diseases; Cell Adhesion; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Humans; Infections; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Vasodilation

1995
Nitric oxide synthase-independent generation of nitric oxide in muscle ischemia--reperfusion injury.
    Nitric oxide : biology and chemistry, 2000, Volume: 4, Issue:6

    Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Mice; Muscle, Skeletal; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury

2000
Isotopic investigation of nitric oxide metabolism in disease.
    Current opinion in clinical nutrition and metabolic care, 2003, Volume: 6, Issue:1

    Topics: Arginine; Biomarkers; Citrulline; Humans; Isotope Labeling; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes

2003
Roles of nitric oxide and superoxide in inflammation.
    Methods in molecular biology (Clifton, N.J.), 2003, Volume: 225

    Topics: 2-Naphthylamine; Animals; Arginine; Blotting, Western; Capillary Permeability; Chemotaxis, Leukocyte; Citrulline; Fluorescent Dyes; Fluorometry; Inflammation; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Rats; Superoxides; Tyrosine

2003
Nitric oxide in plants: production and cross-talk with Ca2+ signaling.
    Molecular plant, 2008, Volume: 1, Issue:2

    Topics: Animals; Arabidopsis; Arginine; Calcium; Calcium-Transporting ATPases; Citrulline; Genome, Plant; Mammals; Nitrate Reductase; Nitric Oxide; Nitric Oxide Synthase; Nitriles; Nitrites; Plant Physiological Phenomena; Protein Kinases; Signal Transduction

2008

Trials

12 trial(s) available for nitrites and citrulline

ArticleYear
L-arginine infusion decreases platelet aggregation through an intraplatelet nitric oxide release.
    Thrombosis research, 1997, Oct-15, Volume: 88, Issue:2

    Topics: Adenosine Diphosphate; Adult; Arginine; Blood Pressure; Citrulline; Collagen; Diastole; Female; Humans; Infusions, Intravenous; Nitric Oxide; Nitrites; Placebos; Platelet Aggregation; Systole; Time Factors

1997
Pentoxiphylline reduces nitric oxide production among patients with HIV infection.
    Immunology letters, 2000, Oct-03, Volume: 74, Issue:2

    Topics: Adult; Citrulline; Female; HIV Infections; Humans; Male; Middle Aged; Nitric Oxide; Nitrites; Pentoxifylline; Tumor Necrosis Factor-alpha

2000
Increased nitric oxide production in patients with systemic sclerosis.
    Nitric oxide : biology and chemistry, 2000, Volume: 4, Issue:6

    Topics: Biomarkers; Citrulline; Female; Humans; Male; Multivariate Analysis; Nitric Oxide; Nitrites; Predictive Value of Tests; Scleroderma, Systemic; Severity of Illness Index; Vital Capacity

2000
Effects of L-citrulline oral supplementation on polymorphonuclear neutrophils oxidative burst and nitric oxide production after exercise.
    Free radical research, 2009, Volume: 43, Issue:9

    Topics: Administration, Oral; Arginine; Bicycling; Citrulline; Creatine Kinase; Dietary Supplements; DNA Damage; Double-Blind Method; Exercise; Humans; L-Lactate Dehydrogenase; Malates; Male; Malondialdehyde; Neutrophil Activation; Neutrophils; Nitric Oxide; Nitrites; Respiratory Burst; Time Factors; Young Adult

2009
L-citrulline-malate influence over branched chain amino acid utilization during exercise.
    European journal of applied physiology, 2010, Volume: 110, Issue:2

    Topics: Administration, Oral; Amino Acids, Branched-Chain; Arginine; Bicycling; Biomarkers; Citrulline; Creatinine; Dietary Proteins; Dietary Supplements; Double-Blind Method; Exercise; Human Growth Hormone; Humans; Insulin; Malates; Male; Muscle, Skeletal; Nitrites; Ornithine; Time Factors; Urea; Young Adult

2010
Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:7

    Topics: Acute Chest Syndrome; Acute Disease; Administration, Oral; Adolescent; Anemia, Sickle Cell; Arginine; Aspartic Acid; Breath Tests; Child; Citrulline; Female; Glutamic Acid; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Young Adult

2010
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:11

    Topics: Area Under Curve; Arginine; Biomarkers; Citrulline; Cyclic GMP; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites

2010
Urinary citrulline in very low birth weight preterm infants receiving intravenous nutrition.
    The British journal of nutrition, 2012, Volume: 108, Issue:7

    Topics: Biomarkers; Child Development; Citrulline; Energy Intake; France; Gastrointestinal Tract; Humans; Infant Nutritional Physiological Phenomena; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Male; Multivariate Analysis; Nitrates; Nitrites; Parenteral Nutrition; Parenteral Nutrition, Total; Pilot Projects

2012
Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis.
    Journal of the International Society of Sports Nutrition, 2015, Volume: 12

    Topics: Adolescent; Adult; Animals; Arginine; Biomarkers; Body Mass Index; Citrulline; Cyclic GMP; Dietary Supplements; Double-Blind Method; Glutathione; Healthy Volunteers; Human Umbilical Vein Endothelial Cells; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Resistance Training; Young Adult

2015
Effects of Citrulline Malate and Beetroot Juice Supplementation on Blood Flow, Energy Metabolism, and Performance During Maximum Effort Leg Extension Exercise.
    Journal of strength and conditioning research, 2019, Volume: 33, Issue:9

    Topics: Adolescent; Adult; Beta vulgaris; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Energy Metabolism; Exercise; Femoral Artery; Fruit and Vegetable Juices; Humans; Malates; Male; Nitrates; Nitrites; Performance-Enhancing Substances; Plant Roots; Quadriceps Muscle; Regional Blood Flow; Ultrasonography; Young Adult

2019
Oxidative stress and nitrate/nitrite (NOx) status following citrulline supplementation in type 2 diabetes: a randomised, double-blind, placebo-controlled trial.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2021, Volume: 34, Issue:1

    Topics: Adult; Antioxidants; Blood Glucose; Citrulline; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Glutathione Peroxidase; Humans; Iran; Male; Malondialdehyde; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Superoxide Dismutase

2021
Short-Term Supplementation of Sodium Nitrate vs. Sodium Chloride Increases Homoarginine Synthesis in Young Men Independent of Exercise.
    International journal of molecular sciences, 2022, Sep-13, Volume: 23, Issue:18

    Topics: Arginine; Citrulline; Creatine; Creatinine; Dietary Supplements; Glutamates; Glutamine; Glycine; Homoarginine; Humans; Lysine; Male; Malondialdehyde; Methyltransferases; Nitrates; Nitrites; Ornithine; Phenylalanine; Sarcosine; Sodium Chloride; Tryptophan; Tyrosine

2022

Other Studies

135 other study(ies) available for nitrites and citrulline

ArticleYear
Pterins inhibit nitric oxide synthase activity in rat alveolar macrophages.
    British journal of pharmacology, 1992, Volume: 107, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cells, Cultured; Citrulline; Hypoxanthines; Interferon-gamma; Macrophages, Alveolar; Male; Nitric Oxide Synthase; Nitrites; Pteridines; Pterins; Rats; Rats, Wistar; Recombinant Proteins

1992
L-arginine as an antihypertensive agent.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12

    Topics: Antihypertensive Agents; Arginine; Blood Pressure; Cardiac Output; Citrulline; Cushing Syndrome; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Injections, Intravenous; Nitrates; Nitrites

1992
Diminished capacity to release metabolites of nitric oxide synthase in macrophages loaded with oxidized low-density lipoproteins.
    European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Cell Line; Cholesterol; Citrulline; Foam Cells; Interferon-gamma; Lipopolysaccharides; Lipoproteins, LDL; Macrophages; Mice; Nitric Oxide Synthase; Nitrites; Recombinant Proteins

1992
Induction of nitric oxide synthase is a necessary precondition for expression of tumor necrosis factor-independent tumoricidal activity by activated macrophages.
    Biochemical and biophysical research communications, 1992, May-15, Volume: 184, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bone Marrow; Cell Line; Cell Survival; Cells, Cultured; Citrulline; Drug Resistance; Enterococcus faecalis; Escherichia coli; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mast-Cell Sarcoma; Moraxella catarrhalis; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Onium Compounds; Peptidoglycan; Phagocytes; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha

1992
Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide.
    The Journal of biological chemistry, 1992, Nov-15, Volume: 267, Issue:32

    Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Western; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Induction; Free Radicals; Kinetics; Mammary Neoplasms, Experimental; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Ribonucleotide Reductases; Tumor Cells, Cultured; Tyrosine

1992
L-arginine and arginine analogues: effects on isolated blood vessels and cultured endothelial cells.
    British journal of pharmacology, 1990, Volume: 101, Issue:1

    Topics: Animals; Arginine; Cattle; Citrulline; Endothelium, Vascular; Guanethidine; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Inbred Strains; Stereoisomerism; Swine

1990
Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Apr-01, Volume: 144, Issue:7

    Topics: Animals; Arginine; Citrulline; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitrates; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Toxoplasma

1990
Temporal expression of different pathways of 1-arginine metabolism in healing wounds.
    Journal of immunology (Baltimore, Md. : 1950), 1990, May-15, Volume: 144, Issue:10

    Topics: Animals; Arginase; Arginine; Cells, Cultured; Citrulline; Hydrolases; In Vitro Techniques; Macrophages; Male; Neutrophils; Nitrites; Ornithine; Rats; Urea; Wound Healing

1990
Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite.
    Science (New York, N.Y.), 1987, Jan-23, Volume: 235, Issue:4787

    Topics: Ammonia; Animals; Cells, Cultured; Citrulline; Cytotoxicity, Immunologic; Homoarginine; Hydrolases; Macrophage Activation; Macrophages; Mice; Nitrates; Nitrites

1987
Antiproliferative activity of gamma-interferon combined with lipopolysaccharide on murine adenocarcinoma: dependence on an L-arginine metabolism with production of nitrite and citrulline.
    Cancer research, 1989, Apr-15, Volume: 49, Issue:8

    Topics: Adenocarcinoma; Animals; Arginine; Cell Division; Citrulline; Interferon-gamma; Kinetics; Lipopolysaccharides; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nitrites; Recombinant Proteins; Tumor Cells, Cultured

1989
Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor.
    The Journal of biological chemistry, 1989, Nov-25, Volume: 264, Issue:33

    Topics: Animals; Arginine; Biopterins; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Kinetics; Macrophages; NADP; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction

1989
Kupffer cell cytotoxicity to hepatocytes in coculture requires L-arginine.
    Archives of surgery (Chicago, Ill. : 1960), 1989, Volume: 124, Issue:12

    Topics: Animals; Arginine; Aspartate Aminotransferases; Cell Survival; Cells, Cultured; Citrulline; Infections; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; omega-N-Methylarginine; Protein Biosynthesis; Rats; Rats, Inbred Strains

1989
Evidence that activation of Kupffer cells results in production of L-arginine metabolites that release cell-associated iron and inhibit hepatocyte protein synthesis.
    Surgery, 1989, Volume: 106, Issue:2

    Topics: Animals; Arginine; Citrulline; Culture Media; Iron; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; Protein Biosynthesis; Proteins; Rats

1989
Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:18

    Topics: Arginine; Citrulline; Humans; Hydrogen Peroxide; Macrophage Activation; Macrophages; Morpholines; Nitrates; Nitrites; Nitrosamines; Superoxides

1987
An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro.
    The Journal of experimental medicine, 1989, Apr-01, Volume: 169, Issue:4

    Topics: Animals; Arginine; Citrulline; In Vitro Techniques; Kupffer Cells; Lipopolysaccharides; Liver; Nitrates; Nitrites; Protein Biosynthesis; Rats; Rats, Inbred Strains

1989
Cytokines induce an L-arginine-dependent effector system in nonmacrophage cells.
    Journal of leukocyte biology, 1988, Volume: 44, Issue:1

    Topics: Animals; Arginine; Biological Products; Citrulline; Cytokines; Humans; Lipopolysaccharides; Mammary Neoplasms, Experimental; Nitrates; Nitrites; Tumor Cells, Cultured; Urea

1988
Kinetics of nitrosamide formation from alkylureas, N-alkylurethans, and alkylguanidines: possible implications for the etiology of human gastric cancer.
    Journal of the National Cancer Institute, 1971, Volume: 46, Issue:6

    Topics: Arginine; Carcinogens; Chemical Phenomena; Chemistry; Citrulline; Diet; Guanidines; Humans; Kinetics; Nitrites; Nitroso Compounds; Nitrosoguanidines; Nitrosourea Compounds; Sodium; Spectrophotometry; Stomach Neoplasms; Urea; Urethane

1971
Biochemical characterization of arginine muants in Schizosaccharomyces pombe and the possibility of repression.
    Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie, 1967, Volume: 9, Issue:3

    Topics: Arginine; Ascomycota; Citrulline; Culture Media; Enzyme Repression; Mutation; Neurospora; Nitrites; Ornithine; Proline; Radiation Genetics; Succinates

1967
L-arginine deficiency and hemodynamic changes as a result of arginase efflux following orthotopic liver transplantation.
    Transplantation proceedings, 1995, Volume: 27, Issue:5

    Topics: Adult; Arginase; Arginine; Blood Pressure; Citrulline; Diastole; Female; Humans; Liver Transplantation; Male; Monitoring, Intraoperative; Nitrates; Nitrites; Ornithine; Pulmonary Wedge Pressure; Reperfusion

1995
Age-dependent changes of NO synthase activity in the rat brain.
    Biochemical and biophysical research communications, 1995, Oct-24, Volume: 215, Issue:3

    Topics: Aging; Animals; Brain; Brain Stem; Calcium; Cerebellum; Citrulline; Frontal Lobe; Hippocampus; In Vitro Techniques; Male; Nitric Oxide Synthase; Nitrites; Organ Specificity; Parietal Lobe; Rats; Rats, Wistar

1995
An L-arginine-nitric oxide-cyclic guanosine monophosphate system exists in the uterus and inhibits contractility during pregnancy.
    American journal of obstetrics and gynecology, 1994, Volume: 170, Issue:1 Pt 1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Culture Techniques; Cyclic GMP; Dose-Response Relationship, Drug; Female; Labor, Obstetric; Methylene Blue; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley; Uterine Contraction; Uterus

1994
Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimulation.
    Biochemical and biophysical research communications, 1994, Feb-15, Volume: 198, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Epithelium; Guanidines; Interferon-gamma; Interleukin-1; Kinetics; Lung; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Recombinant Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha

1994
Interleukin-1 beta and tumor necrosis factor-alpha synergistically induce NO synthase in rat vascular smooth muscle cells.
    The American journal of physiology, 1994, Volume: 266, Issue:4 Pt 2

    Topics: Amino Acid Oxidoreductases; Animals; Cells, Cultured; Citrulline; Cyclic GMP; Drug Synergism; Enzyme Induction; Gene Expression; Interleukin-1; Lipopolysaccharides; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Rats; Recombinant Proteins; Tumor Necrosis Factor-alpha

1994
Nitric-oxide synthase assays.
    Methods in enzymology, 1994, Volume: 233

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chromatography, Ion Exchange; Citrulline; Dithiothreitol; Hemoglobins; Indicators and Reagents; Mammals; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Pterins; Sensitivity and Specificity; Spectrophotometry

1994
Nitric oxide as a mediator of oxidant lung injury due to paraquat.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-02, Volume: 91, Issue:16

    Topics: Amino Acid Oxidoreductases; Animals; Calcium; Citrulline; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidants; Paraquat; Perfusion; Respiration

1994
Hydrogen peroxide-supported oxidation of NG-hydroxy-L-arginine by nitric oxide synthase.
    Biochemistry, 1995, Feb-14, Volume: 34, Issue:6

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Benzene Derivatives; Cell Line; Citrulline; Hydrogen Peroxide; Kinetics; Macrophages; Mice; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Oxygen; Peroxides; tert-Butylhydroperoxide

1995
Identification of constitutive and inducible forms of nitric oxide synthase in human platelets.
    The Journal of laboratory and clinical medicine, 1995, Volume: 125, Issue:3

    Topics: Amino Acid Oxidoreductases; Arginine; Blood Platelets; Citrulline; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Humans; Nitric Oxide Synthase; Nitrites; Nitroarginine; Platelet Aggregation; Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic

1995
Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta-stimulated rat mesangial cells.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Northern; Cell Nucleus; Citrulline; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transcription, Genetic

1995
Increase in serum NG-hydroxy-L-arginine in rats treated with bacterial lipopolysaccharide.
    European journal of pharmacology, 1995, Feb-24, Volume: 275, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Escherichia coli; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Stereoisomerism

1995
Nitric oxide synthase activity in molluscan hemocytes.
    FEBS letters, 1995, May-29, Volume: 365, Issue:2-3

    Topics: Amino Acid Oxidoreductases; Animals; Antibodies; Arginine; Citrulline; Hemocytes; Kinetics; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rabbits; Snails

1995
Erythrocyte stages of Plasmodium falciparum exhibit a high nitric oxide synthase (NOS) activity and release an NOS-inducing soluble factor.
    The Journal of experimental medicine, 1995, Sep-01, Volume: 182, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Factors; Canavanine; Cell Adhesion; Cells, Cultured; Citrulline; Culture Media, Conditioned; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Erythrocytes; Host-Parasite Interactions; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Plasmodium; Plasmodium falciparum; Protozoan Proteins; Species Specificity; Umbilical Veins

1995
Nitric oxide synthase activity is inducible in rat, but not rabbit alveolar macrophages, with a concomitant reduction in arginase activity.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 351, Issue:6

    Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Female; In Vitro Techniques; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Sprague-Dawley

1995
Release of reactive oxygen and nitrogen intermediates from monocytes of patients with pulmonary tuberculosis.
    Scandinavian journal of clinical and laboratory investigation, 1995, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Citrulline; Electron Transport; Female; Follow-Up Studies; Humans; Macrophages; Male; Middle Aged; Monocytes; Nitrites; Nitrogen Compounds; Reactive Oxygen Species; Tuberculosis, Pulmonary

1995
Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside.
    Diabetologia, 1993, Volume: 36, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Female; Islets of Langerhans; Kinetics; Macrophage Activation; Macrophages; Male; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Thionucleotides

1993
Nitric oxide synthase induces macrophage death by apoptosis.
    Biochemical and biophysical research communications, 1993, Mar-15, Volume: 191, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Cells, Cultured; Citrulline; Female; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Nitric Oxide Synthase; Nitrites

1993
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine.
    European journal of pharmacology, 1993, Mar-16, Volume: 233, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Guanidines; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence

1993
LPS-induced activation of primed murine peritoneal macrophages is modulated by prostaglandins and cyclic nucleotides.
    Cellular immunology, 1993, Volume: 149, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Cell Division; Citrulline; Cord Factors; Cyclic AMP; Indomethacin; Lipopolysaccharides; Macrophage Activation; Mice; Nitric Oxide Synthase; Nitrites; Prostaglandins; Tumor Cells, Cultured

1993
Cytokines induce nitric oxide production in mouse osteoblasts.
    Biochemical and biophysical research communications, 1994, Jun-15, Volume: 201, Issue:2

    Topics: 3T3 Cells; Animals; Arginine; Cell Line; Cell Survival; Citrulline; Cycloheximide; Cytokines; Dactinomycin; Dexamethasone; Egtazic Acid; Escherichia coli; Humans; Indomethacin; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Osteoblasts; Recombinant Proteins; Tumor Necrosis Factor-alpha

1994
Protection against hepatic ischemia/reperfusion injury by exogenous L-arginine.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Animals; Arginine; Citrulline; Cyclic GMP; Liver; Liver Circulation; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury

1996
Decreased L-arginine-nitric oxide pathway in cultured myoblasts from spontaneously hypertensive versus normotensive Wistar-Kyoto rats.
    FEBS letters, 1996, Sep-02, Volume: 392, Issue:3

    Topics: Animals; Cell Division; Cells, Cultured; Citrulline; Culture Media; Mitosis; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred SHR; Rats, Wistar

1996
Biological control and inhibition of induction of nitric oxide synthase.
    Methods in enzymology, 1996, Volume: 268

    Topics: Animals; Blotting, Northern; Blotting, Western; Cell Line; Citrulline; Colorimetry; Enzyme Induction; Ethylenediamines; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Lung; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Radioisotope Dilution Technique; Rats; RNA, Messenger; Signal Transduction; Sulfanilamides; Transcription, Genetic; Tritium

1996
Effect of a nitric oxide synthase inhibitor, S-ethylisothiourea, on cultured cells and cardiovascular functions of normal and lipopolysaccharide-treated rabbits.
    Journal of biochemistry, 1996, Volume: 119, Issue:3

    Topics: Animals; Blood Pressure; Brain; Cells, Cultured; Citrulline; Colforsin; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Interleukin-1; Isothiuronium; L-Lactate Dehydrogenase; Lipopolysaccharides; Nitric Oxide Synthase; Nitrites; Nucleosomes; Rabbits; Rats; Shock, Septic

1996
Dual effects of oxidized low-density lipoprotein on immune-stimulated nitric oxide and prostaglandin release in macrophages.
    European journal of pharmacology, 1996, Feb-29, Volume: 298, Issue:1

    Topics: Animals; Cells, Cultured; Citrulline; Indomethacin; Interferon-gamma; Lipopolysaccharides; Lipoproteins, LDL; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Prostaglandins

1996
Whole body nitric oxide synthesis in healthy men determined from [15N] arginine-to-[15N]citrulline labeling.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Oct-15, Volume: 93, Issue:21

    Topics: Adult; Arginine; Citrulline; Eating; Fasting; Humans; Isotope Labeling; Male; Models, Biological; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes; Time Factors

1996
Plasma reactive nitrogen intermediate levels in patients with clinically active rheumatoid arthritis.
    The Indian journal of medical research, 1996, Volume: 104

    Topics: Adult; Arthritis, Rheumatoid; Citrulline; Female; Free Radicals; Humans; Male; Methotrexate; Nitrites; Nitrogen

1996
Depolymerization of macrophage microfilaments prevents induction and inhibits activity of nitric oxide synthase.
    European journal of cell biology, 1996, Volume: 71, Issue:4

    Topics: Actin Cytoskeleton; Amino Acid Sequence; Animals; Cells, Cultured; Citrulline; Colchicine; Cytochalasin B; Enzyme Induction; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nitric Oxide Synthase; Nitrites; Recombinant Proteins

1996
Inducible nitric oxide synthase in rat brown adipocytes: implications for blood flow to brown adipose tissue.
    Endocrinology, 1997, Volume: 138, Issue:2

    Topics: Adipocytes; Adipose Tissue, Brown; Animals; Arginine; Cells, Cultured; Citrulline; Dactinomycin; Enzyme Induction; Enzyme Inhibitors; Kinetics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Norepinephrine; Rats; Rats, Sprague-Dawley; Regional Blood Flow

1997
Evidence for the presence of an unusual nitric oxide- and citrulline-producing enzyme in rat kidney.
    Biochemical and biophysical research communications, 1997, Mar-27, Volume: 232, Issue:3

    Topics: Animals; Calcium; Calmodulin; Citrulline; Enzyme Inhibitors; Female; Guinea Pigs; Isoenzymes; Isothiuronium; Kidney; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pregnancy; Rats; Rats, Sprague-Dawley; Sepharose

1997
Nitrites and L-citrulline levels in copper intrauterine device users.
    Contraception, 1997, Volume: 55, Issue:5

    Topics: Citrulline; Female; Humans; Intrauterine Devices, Copper; Leukocytes, Mononuclear; Nitric Oxide; Nitrites; Superoxides; Uterus

1997
Role of exogenous L-arginine in hepatic ischemia-reperfusion injury.
    The Journal of surgical research, 1997, Volume: 69, Issue:2

    Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Citrulline; Cyclic GMP; Female; Hemodynamics; Liver; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Reperfusion Injury; Swine; Time Factors

1997
Post-transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines.
    FEBS letters, 1997, Jun-30, Volume: 410, Issue:2-3

    Topics: Animals; Arginine; Citrulline; Doxycycline; Hydrocortisone; Macrophages; Mice; Minocycline; Molecular Structure; Nitric Oxide Synthase; Nitrites; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetracyclines

1997
Identification of nitric oxide synthase in human and bovine oviduct.
    Molecular human reproduction, 1996, Volume: 2, Issue:8

    Topics: Animals; Arginine; Cattle; Cells, Cultured; Citrulline; Epithelial Cells; Epithelium; Fallopian Tubes; Female; Humans; In Vitro Techniques; NADPH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitrites

1996
Low-density lipoprotein-induced formation of nitric oxide by cultured vascular smooth muscle cells of the rat.
    European journal of clinical investigation, 1997, Volume: 27, Issue:7

    Topics: Animals; Cells, Cultured; Citrulline; Cyclic GMP; Female; Humans; Lipoproteins, LDL; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Thymidine

1997
Nitric oxide metabolism in wounds.
    The Journal of surgical research, 1997, Jul-15, Volume: 71, Issue:1

    Topics: Animals; Citrulline; Enzyme Induction; Macrophages; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Nitrites; Ornithine; Skin; Time Factors; Wound Healing

1997
Ketamine inhibits nitric oxide synthase in lipopolysaccharide-treated rat alveolar macrophages.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:9

    Topics: Analysis of Variance; Anesthetics, Dissociative; Animals; Arginine; Blotting, Western; Cell Respiration; Cell Survival; Cells, Cultured; Citrulline; Culture Media; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Enzymologic; Ketamine; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide Synthase; Nitrites; Radiopharmaceuticals; Rats; Rats, Inbred WKY; Tritium; Tumor Necrosis Factor-alpha

1997
Effect of diet induced hypercholesterolemia and selenium supplementation on nitric oxide synthase activity.
    Archives of physiology and biochemistry, 1997, Volume: 105, Issue:6

    Topics: Animals; Antioxidants; Cholesterol; Cholesterol, Dietary; Citrulline; Enzyme Induction; Hypercholesterolemia; Male; Nitric Oxide Synthase; Nitrites; Rabbits; Selenium; Triglycerides

1997
Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine.
    Biochemistry, 1998, Jul-21, Volume: 37, Issue:29

    Topics: Animals; Arginine; Catalysis; Cattle; Citrulline; Homoarginine; Kinetics; NADP; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Oxygen; Substrate Specificity

1998
Factors contributing to differences in the regulation of cGMP in isolated porcine pulmonary vessels.
    European journal of pharmacology, 1998, Jun-19, Volume: 351, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blotting, Western; Carbon Radioisotopes; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Pulmonary Veins; Purinones; Swine

1998
Improved methods to measure end products of nitric oxide in biological fluids: nitrite, nitrate, and S-nitrosothiols.
    Nitric oxide : biology and chemistry, 1997, Volume: 1, Issue:2

    Topics: Body Fluids; Chromatography, Ion Exchange; Citrulline; Humans; Mercaptoethanol; Nitrates; Nitric Oxide; Nitrites; Nitroso Compounds; S-Nitrosothiols; Tumor Cells, Cultured

1997
The induction of nitric oxide by interleukin-12 and tumor necrosis factor-alpha in human natural killer cells: relationship with the regulation of lytic activity.
    Blood, 1998, Sep-15, Volume: 92, Issue:6

    Topics: Adjuvants, Immunologic; Antibodies; Cells, Cultured; Citrulline; Cytotoxicity, Immunologic; Drug Synergism; Enzyme Induction; Granzymes; Guanidines; Humans; Interferon-gamma; Interleukin-12; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lymphocyte Activation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitroprusside; Serine Endopeptidases; Tumor Necrosis Factor-alpha

1998
Nitric oxide synthesis is increased in patients with systemic lupus erythematosus.
    Rheumatology international, 1998, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Analysis of Variance; Citrulline; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Nitric Oxide; Nitrites; Spectrophotometry

1998
Inhibition of astroglial nitric oxide synthase type 2 expression by idazoxan.
    Molecular pharmacology, 1999, Volume: 55, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Arginine; Astrocytes; Cell Line; Cell-Free System; Chloramphenicol O-Acetyltransferase; Citrulline; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Idazoxan; Lipopolysaccharides; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Norepinephrine; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; RNA, Messenger; Time Factors; Tumor Cells, Cultured

1999
Reduced arginine plasma levels are the drive for arginine production by the kidney in the rat.
    Shock (Augusta, Ga.), 1999, Volume: 11, Issue:3

    Topics: Animals; Arginase; Arginine; Blood Chemical Analysis; Cattle; Citrulline; Digestive System; Endotoxemia; Kidney; Liver; Male; Nitrates; Nitrites; Ornithine; Rats; Rats, Wistar; Regional Blood Flow

1999
Effects of ethanol on intraovarian nitric oxide production in the prepubertal rat.
    The Journal of endocrinology, 1999, Volume: 161, Issue:1

    Topics: Animals; Arginine; Blotting, Western; Citrulline; Estradiol; Ethanol; Female; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ovary; Rats; Rats, Sprague-Dawley; Sexual Maturation

1999
Nitric oxide production is low in end-stage renal disease patients on peritoneal dialysis.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Adult; Aged; Arginine; Citrulline; Creatinine; Cyclic GMP; Female; Humans; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Peritoneal Dialysis

1999
Reactive oxygen intermediates and reactive nitrogen intermediates in copper intrauterine device users.
    Contraception, 1999, Volume: 59, Issue:1

    Topics: Chromogenic Compounds; Citrulline; Ethylenediamines; Female; Free Radical Scavengers; Humans; Intrauterine Devices, Copper; Luminescent Measurements; Monocytes; Nitrites; Reactive Oxygen Species; Scintillation Counting; Sulfanilamides; Uterus

1999
Stimulation of NO synthase activity in the immune-competent lepidopteran Estigmene acraea hemocyte line.
    Nitric oxide : biology and chemistry, 1999, Volume: 3, Issue:2

    Topics: Animals; Arginine; Cell Line; Citrulline; Enzyme Activation; Enzyme Inhibitors; Hemocytes; Immunocompetence; Kinetics; Lepidoptera; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Superoxide Dismutase

1999
No detectable NO synthesis from L-arginine or N(G)-hydroxy-L-arginine in fMLP-stimulated human blood neutrophils despite production of nitrite, nitrate, and citrulline from N(G)-hydroxy-L-arginine.
    Journal of leukocyte biology, 1999, Volume: 66, Issue:1

    Topics: Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitroarginine

1999
Cationic proteins inhibit L-arginine uptake in rat alveolar macrophages and tracheal epithelial cells. Implications for nitric oxide synthesis.
    American journal of respiratory cell and molecular biology, 1999, Volume: 21, Issue:2

    Topics: Animals; Arginase; Arginine; Blood Proteins; Citrulline; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Epithelial Cells; Female; Fibrinolytic Agents; Gene Expression; Heparin; Lipopolysaccharides; Lung; Lysine; Macrophages, Alveolar; Male; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Ribonucleases; Time Factors; Trachea

1999
Nitric oxide production is increased in patients with inflammatory myositis.
    Nitric oxide : biology and chemistry, 1999, Volume: 3, Issue:6

    Topics: Adolescent; Adult; Biomarkers; Citrulline; Dermatomyositis; Female; Humans; Inflammation; Male; Methotrexate; Middle Aged; Nitric Oxide; Nitrites; Polymyositis; Prednisolone; Reference Values

1999
Formation and reactions of the heme-dioxygen intermediate in the first and second steps of nitric oxide synthesis as studied by stopped-flow spectroscopy under single-turnover conditions.
    Biochemistry, 2000, Mar-07, Volume: 39, Issue:9

    Topics: Animals; Arginine; Catalysis; Citrulline; Ferrous Compounds; Heme; Kinetics; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Oxygen; Rats; Spectrophotometry

2000
Regulation of ICAM-1/CD54 expression on human endothelial cells by hydrogen peroxide involves inducible NO synthase.
    Journal of leukocyte biology, 2000, Volume: 67, Issue:3

    Topics: Cells, Cultured; Citrulline; Drug Synergism; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-1; Isoenzymes; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2000
Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer.
    The Journal of biological chemistry, 2000, Apr-28, Volume: 275, Issue:17

    Topics: Amino Acid Sequence; Animals; Calcium; Calmodulin; Catalysis; Cell Line; Citrulline; Dose-Response Relationship, Drug; Electron Transport; Escherichia coli; Humans; Insecta; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis; NADH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Protein Binding; Sequence Homology, Amino Acid

2000
Changes of endothelial nitric oxide synthase level and activity during endothelial cell proliferation.
    Endothelium : journal of endothelial cell research, 2000, Volume: 7, Issue:3

    Topics: Animals; Arginine; Cattle; Cell Division; Cells, Cultured; Citrulline; Endothelium, Vascular; Kinetics; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Superoxide Dismutase; Superoxides

2000
Modulation of the nitric oxide pathway by copper in glial cells.
    Biochemical and biophysical research communications, 2000, Sep-07, Volume: 275, Issue:3

    Topics: Animals; Arginine; Citrulline; Copper; Cyclic GMP; Gene Expression Regulation, Enzymologic; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Neuroglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Rats; RNA, Messenger; Tumor Cells, Cultured

2000
Suppression of inducible nitric oxide synthase expression in RAW 264. 7 macrophages by two beta-carboline alkaloids extracted from Melia azedarach.
    European journal of pharmacology, 2000, Oct-20, Volume: 406, Issue:3

    Topics: Alkaloids; Animals; Carbolines; Cell Line; Citrulline; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin-Endoperoxide Synthases

2000
Electrochemical detection of nitroso-arginine as an intermediate between N-hydroxy-arginine and citrulline. An in vitro versus in vivo study using microcarbon electrodes in neuronal nitric oxide synthase and mice brain.
    Neuroscience letters, 2000, Nov-17, Volume: 294, Issue:2

    Topics: Animals; Arginine; Brain; Brain Chemistry; Citrulline; Electrochemistry; Mice; Microelectrodes; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Nitroso Compounds; Oxidation-Reduction; Surface Properties

2000
Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis.
    Nitric oxide : biology and chemistry, 2001, Volume: 5, Issue:1

    Topics: Animals; Arginine; Bivalvia; Citrulline; Enzyme Inhibitors; Hemocytes; Latex; Luminescent Measurements; Microspheres; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Phagocytosis; Superoxide Dismutase; Superoxides

2001
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
    Blood pressure, 2000, Volume: 9, Issue:5

    Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Arginine; Citrulline; Cyclic GMP; Drug Evaluation; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Stereoisomerism

2000
Indomethacin prevents the induction of inducible nitric oxide synthase in murine peritoneal macrophages and decreases their nitric oxide production.
    Life sciences, 2001, Mar-09, Volume: 68, Issue:16

    Topics: Animals; Arginase; Arginine; Blotting, Western; Citrulline; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Indomethacin; Macrophages, Peritoneal; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Uridine

2001
Retinoic acid attenuates inducible nitric oxide synthase (NOS2) activation in cultured rat cardiac myocytes and microvascular endothelial cells.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:5

    Topics: Animals; Arginine; Blotting, Northern; Blotting, Western; Cells, Cultured; Citrulline; Dactinomycin; Endothelium, Vascular; Enzyme Activation; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Macrophages, Alveolar; Male; Microcirculation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Tretinoin

2001
L-citrulline mediated relaxation in the control and lipopolysaccharide-treated rat aortic rings.
    European journal of pharmacology, 2001, Nov-09, Volume: 431, Issue:1

    Topics: Animals; Aorta; Arginine; Citrulline; Corticosterone; Cyclic GMP; Cycloheximide; Glutamine; Guanidines; In Vitro Techniques; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilation

2001
Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome.
    American journal of respiratory and critical care medicine, 2001, Dec-15, Volume: 164, Issue:12

    Topics: Acute Disease; Adolescent; Anemia, Sickle Cell; Arginine; Breath Tests; Child; Citrulline; Forced Expiratory Volume; Genotype; Humans; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Polymorphism, Genetic; Syndrome; Trinucleotide Repeats; Vital Capacity

2001
A brain nitric oxide synthase study in the rat: production of a nitroso-compound NA and absence of nitric oxide synthesis.
    Neuroscience letters, 2002, Mar-15, Volume: 321, Issue:1-2

    Topics: Animals; Arginine; Brain; Citrulline; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nitroso Compounds; Rats

2002
Decreased nitric oxide synthesis in human endothelial cells cultured on type I collagen.
    Circulation research, 2002, Mar-22, Volume: 90, Issue:5

    Topics: Cells, Cultured; Citrulline; Collagen Type I; Endothelium, Vascular; Humans; Integrins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Peptides; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; RNA, Messenger; Signal Transduction

2002
N-Acetylcysteine negatively modulates nitric oxide production in endotoxin-treated rats through inhibition of NF-kappaB activation.
    Antioxidants & redox signaling, 2002, Volume: 4, Issue:1

    Topics: Acetylcysteine; Animals; Citrulline; DNA; Endotoxins; Enzyme Activation; Free Radical Scavengers; Lipopolysaccharides; Male; NF-kappa B; Nitrates; Nitric Oxide; Nitrites; Protein Binding; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2002
Antitubercular therapy decreases nitric oxide production in HIV/TB coinfected patients.
    BMC infectious diseases, 2002, Jul-29, Volume: 2

    Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Biomarkers; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Citrulline; Drug Administration Schedule; Enzyme Inhibitors; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Mycobacterium; Nitric Oxide; Nitrites; Pyrazinamide; Rifampin; T-Lymphocyte Subsets; Tuberculosis

2002
NO synthesis and its regulation in the arachidonic-acid-stimulated rat polymorphonuclear leukocytes.
    Nitric oxide : biology and chemistry, 2002, Volume: 7, Issue:2

    Topics: Animals; Arachidonic Acid; Calcium; Calmodulin; Citrulline; Free Radical Scavengers; Free Radicals; Hyperoxia; Neutrophils; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2002
Inducible nitric oxide synthase is expressed in synovial fluid granulocytes.
    Clinical and experimental immunology, 2002, Volume: 130, Issue:1

    Topics: Adult; Aged; Arginine; Arthritis, Rheumatoid; Autoimmune Diseases; Blood Cells; Chromatography, High Pressure Liquid; Citrulline; Colorimetry; Enzyme Induction; Exudates and Transudates; Female; Granulocytes; Humans; Knee; Male; Membrane Proteins; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Organ Specificity; Synovial Fluid

2002
Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites are increased in dementia with Lewy bodies.
    Neuroscience letters, 2002, Nov-22, Volume: 333, Issue:2

    Topics: Aged; Arginine; Citrulline; Female; Humans; Lewy Body Disease; Male; Nitrates; Nitrites

2002
Nitric oxide synthesis in human nonpregnant myometrium and uterine myomas.
    Fertility and sterility, 2003, Volume: 79 Suppl 1

    Topics: Adult; Citrulline; Estradiol; Female; Humans; Middle Aged; Myoma; Myometrium; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Progesterone; Prospective Studies; Tumor Cells, Cultured; Uterine Neoplasms

2003
Nitric oxide pathway and response to nitroglycerin in cluster headache patients: plasma nitrite and citrulline levels.
    Cephalalgia : an international journal of headache, 2003, Volume: 23, Issue:6

    Topics: Adult; Analysis of Variance; Citrulline; Cluster Headache; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitrites; Nitroglycerin; Signal Transduction

2003
Characterization of suppression of nitric oxide production by carbon monoxide poisoning in the striatum of free-moving rats, as determined by in vivo brain microdialysis.
    Brain research, 2003, Jul-25, Volume: 979, Issue:1-2

    Topics: Animals; Arginine; Carbon Monoxide Poisoning; Citrulline; Corpus Striatum; Extracellular Space; Isomerism; Male; Microdialysis; Movement; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley

2003
Role of ascorbate in the regulation of nitric oxide generation by polymorphonuclear leukocytes.
    Biochemical and biophysical research communications, 2003, Sep-12, Volume: 309, Issue:1

    Topics: Animals; Ascorbic Acid; Biopterins; Blood Platelets; Citrulline; Dehydroascorbic Acid; Flow Cytometry; Haplorhini; Humans; Iodoacetamide; Male; Neutrophils; Nitric Oxide; Nitrites; Oxidation-Reduction; Oxygen; Rats; Rats, Sprague-Dawley

2003
Depletion of serum L-arginine in patients with acute pancreatitis.
    Pancreas, 2003, Volume: 27, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Alcoholism; Amylases; Arginine; C-Reactive Protein; Cholecystitis, Acute; Citrulline; Female; Gallstones; Humans; Male; Middle Aged; Nitrates; Nitrites; Pancreatitis; Pancreatitis, Alcoholic; Recurrence; Time Factors

2003
Structural elements contribute to the calcium/calmodulin dependence on enzyme activation in human endothelial nitric-oxide synthase.
    The Journal of biological chemistry, 2003, Dec-26, Volume: 278, Issue:52

    Topics: Amino Acid Sequence; Animals; Baculoviridae; Calcium; Calmodulin; Catalysis; Chelating Agents; Citrulline; Culture Media; Cytochromes c; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Ferricyanides; Gene Deletion; Humans; Insecta; Molecular Sequence Data; Mutation; NADP; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oxygen; Protein Structure, Tertiary; Sequence Homology, Amino Acid

2003
Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Dec-09, Volume: 100, Issue:25

    Topics: Animals; Arginine; Catalysis; Chromatography, High Pressure Liquid; Citrulline; Electrochemistry; Escherichia coli; Feedback, Physiological; Hydrogen Peroxide; Inflammation; Kinetics; Mice; Milk; Models, Biological; Models, Chemical; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxygen; Peroxidase; Protein Binding; RNA, Messenger; Spectrophotometry; Time Factors; Ultraviolet Rays; Up-Regulation

2003
Role of the W07-toxin on Vibrio cholerae-induced diarrhoea.
    Biochimica et biophysica acta, 2004, Jan-05, Volume: 1670, Issue:1

    Topics: Animals; Bacterial Toxins; Calcium; Catalase; Cells, Cultured; Citrulline; Diarrhea; Disease Models, Animal; Dose-Response Relationship, Drug; Enterocytes; Inositol Phosphates; Intestine, Small; Luminescent Measurements; Mice; Mice, Inbred BALB C; Nitrites; Phospholipase C gamma; Protein Kinase C; Signal Transduction; Time Factors; Type C Phospholipases; Vibrio cholerae

2004
Activation of the nitric oxide response in gilthead seabream after experimental infection with Photobacterium damselae subsp. piscicida.
    Fish & shellfish immunology, 2004, Volume: 16, Issue:5

    Topics: Analysis of Variance; Animals; Bacterial Capsules; Body Constitution; Citrulline; Fish Diseases; Glucose; Gram-Negative Bacterial Infections; Lethal Dose 50; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Photobacterium; Sea Bream; Time Factors; Virulence

2004
Increased (E)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression.
    Journal of affective disorders, 2004, Volume: 80, Issue:2-3

    Topics: Aldehydes; Arginine; Citrulline; Coronary Disease; Depressive Disorder, Major; Female; Glutathione; Humans; Lipid Peroxidation; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites

2004
Role of nitric oxide pathway in hypotensive and renal effects of furosemide during extracellular volume expansion.
    Journal of hypertension, 2004, Volume: 22, Issue:8

    Topics: Animals; Blood Pressure; Blood Volume; Carbon Radioisotopes; Citrulline; Diuresis; Diuretics; Extracellular Fluid; Furosemide; Hypotension; Kidney; Male; NADPH Dehydrogenase; Natriuresis; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Renal Circulation

2004
Nitric oxide formation in the oropharyngeal tract: possible influence of cigarette smoking.
    Nitric oxide : biology and chemistry, 2004, Volume: 11, Issue:3

    Topics: Adult; Aged; Biopsy; Citrulline; Humans; Immunohistochemistry; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Oropharynx; Saliva; Smoking

2004
Direct single cell determination of nitric oxide synthase related metabolites in identified nitrergic neurons.
    Journal of inorganic biochemistry, 2005, Volume: 99, Issue:4

    Topics: Animals; Arginine; Argininosuccinic Acid; Cells, Cultured; Citrulline; Electric Conductivity; Electrophoresis, Capillary; Ganglia, Invertebrate; Intracellular Fluid; Lymnaea; Microscopy, Fluorescence; Nitrates; Nitrergic Neurons; Nitric Oxide Synthase; Nitrites; Ornithine

2005
Increased NO production in lysinuric protein intolerance.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:2

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acid Transport System y+L; Cells, Cultured; Child; Citrulline; Fibroblasts; Fusion Regulatory Protein 1, Light Chains; Humans; Lysine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites

2005
Effects of acute ammonia toxicity on nitric oxide (NO), citrulline-NO cycle enzymes, arginase and related metabolites in different regions of rat brain.
    Neuroscience research, 2005, Volume: 53, Issue:2

    Topics: Amino Acids; Ammonia; Animals; Arginase; Argininosuccinate Lyase; Argininosuccinate Synthase; Brain; Citrulline; gamma-Aminobutyric Acid; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley

2005
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Sep-20, Volume: 102, Issue:38

    Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Arteriosclerosis; Ascorbic Acid; Citrulline; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Diet, Atherogenic; DNA-Binding Proteins; Endothelium, Vascular; ets-Domain Protein Elk-1; Humans; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Proto-Oncogene Proteins; Rabbits; Superoxides; Transcription Factors; Vasodilation; Vitamin E

2005
Vascular and renal effects of dopamine during extracellular volume expansion: Role of nitric oxide pathway.
    Life sciences, 2006, Feb-28, Volume: 78, Issue:14

    Topics: Animals; Aorta; Arginine; Blood Pressure; Citrulline; Diuresis; Dopamine; Dopamine Antagonists; Extracellular Fluid; Haloperidol; Kidney; Male; NADPH Dehydrogenase; Natriuresis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Renal Artery; Renal Plasma Flow

2006
Increased nitric oxide (NO) pathway metabolites in the vitreous fluid of patients with rhegmatogenous retinal detachment or diabetic traction retinal detachment.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2006, Volume: 244, Issue:6

    Topics: Aged; Arginine; Chromatography, High Pressure Liquid; Citrulline; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Retinal Detachment; Signal Transduction; Vitreous Body

2006
Blood cell NO synthesis in response to exercise.
    Nitric oxide : biology and chemistry, 2006, Volume: 15, Issue:1

    Topics: Adult; Arginase; Arginine; Bicycling; Citrulline; Erythrocytes; Exercise; Humans; Lymphocytes; Male; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Ornithine; Superoxide Dismutase

2006
Infected chronic wounds show different local and systemic arginine conversion compared with acute wounds.
    The Journal of surgical research, 2006, Volume: 134, Issue:2

    Topics: Acute Disease; Adult; Amino Acids; Arginase; Arginine; Body Fluids; Chronic Disease; Citrulline; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Ornithine; Prospective Studies; Wound Healing; Wound Infection; Wounds and Injuries

2006
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2007, Volume: 107, Issue:5

    Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Nitric Oxide Synthase; Nitrites; Subarachnoid Hemorrhage; Vasospasm, Intracranial

2007
Measurement of NO and NO synthase.
    Current protocols in neuroscience, 2001, Volume: Chapter 7

    Topics: Animals; Arginine; Citrulline; Colorimetry; Ethylenediamines; Luminescent Measurements; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Sulfanilamides

2001
Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia.
    Neurochemistry international, 2008, Volume: 53, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Citrulline; Dementia, Multi-Infarct; Female; Functional Laterality; Glutamine; Hippocampus; Humans; Isoenzymes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Schizophrenia; Signal Transduction

2008
Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy.
    Amino acids, 2009, Volume: 37, Issue:4

    Topics: Adult; Aged; Arginine; Blood Platelets; Carcinoma, Renal Cell; Citrulline; Female; Humans; Interferon-alpha; Kidney Neoplasms; Male; Melanoma; Middle Aged; Monoamine Oxidase; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Skin Neoplasms

2009
Nitric oxide (NO), citrulline-NO cycle enzymes, glutamine synthetase, and oxidative status in kainic acid-mediated excitotoxicity in rat brain.
    Drug and chemical toxicology, 2009, Volume: 32, Issue:4

    Topics: Animals; Aspartic Acid; Brain; Citrulline; Endothelium, Vascular; Glutamate-Ammonia Ligase; Kainic Acid; Muscle Relaxation; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; RNA, Messenger

2009
Level of nitrated proteins in the plasma, platelets and liver of patients with liver cirrhosis.
    Redox report : communications in free radical research, 2009, Volume: 14, Issue:6

    Topics: Adult; Blood Platelets; Citrulline; Female; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide; Nitrites; Plasma; Proteins

2009
Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.
    Neurochemistry international, 2010, Volume: 56, Issue:4

    Topics: Animals; Arginine; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic AMP; Cyclic GMP; Enzyme Activation; Excitatory Amino Acid Agonists; Guanylate Cyclase; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Oncogene Protein v-akt; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate

2010
Surfactant blocks lipopolysaccharide signaling by inhibiting both NFκB and PARP activation in experimental ARDS.
    Molecular and cellular biochemistry, 2011, Volume: 354, Issue:1-2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Alveolar Epithelial Cells; Animals; Bronchoalveolar Lavage Fluid; Citrulline; Drug Combinations; Enzyme Activation; Fatty Alcohols; Hydrogen-Ion Concentration; I-kappa B Kinase; Lipopolysaccharides; Lung; Male; NF-kappa B; Nitric Oxide Synthase Type II; Nitrites; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polyethylene Glycols; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Swine

2011
Continuous exposure to L-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells.
    Amino acids, 2012, Volume: 43, Issue:3

    Topics: Arginase; Arginine; Ascorbic Acid; Cells, Cultured; Citrulline; Culture Media; Down-Regulation; Drug Tolerance; Free Radical Scavengers; Gene Expression; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Polyethylene Glycols; Superoxide Dismutase; Superoxides

2012
Circulating microparticles carry a functional endothelial nitric oxide synthase that is decreased in patients with endothelial dysfunction.
    Journal of the American Heart Association, 2012, Dec-31, Volume: 2, Issue:1

    Topics: Adult; Arginine; Biomarkers; Blotting, Western; Case-Control Studies; Cell-Derived Microparticles; Cells, Cultured; Citrulline; Coronary Stenosis; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Immunoprecipitation; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Reactive Oxygen Species; Time Factors; Vasodilation; Young Adult

2012
Unilateral nephrectomy causes an early abrupt decrease in plasma arginine and simultaneous reduction in glomerular filtration rate in living kidney donors.
    Clinical biochemistry, 2013, Volume: 46, Issue:15

    Topics: Arginine; Citrulline; Creatinine; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Transplantation; Living Donors; Male; Middle Aged; Nephrectomy; Nitric Oxide; Nitrites; Ornithine; Phenylalanine; Thiobarbituric Acid Reactive Substances; Urea

2013
Circulating blood endothelial nitric oxide synthase contributes to the regulation of systemic blood pressure and nitrite homeostasis.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:8

    Topics: Animals; Arginine; Blood Pressure; Carbon Radioisotopes; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Erythrocytes; Homeostasis; Hypertension; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Signal Transduction

2013
Disturbance of redox homeostasis by ornithine and homocitrulline in rat cerebellum: a possible mechanism of cerebellar dysfunction in HHH syndrome.
    Life sciences, 2013, Aug-06, Volume: 93, Issue:4

    Topics: Aconitate Hydratase; Animals; Cerebellum; Citrulline; Creatine Kinase; Electron Transport; Glutathione; Homeostasis; Hydrogen Peroxide; Hyperammonemia; Ketoglutarate Dehydrogenase Complex; Nerve Tissue Proteins; Nitrates; Nitrites; Ornithine; Oxidation-Reduction; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances; Urea Cycle Disorders, Inborn

2013
Increased erythrocytes by-products of arginine catabolism are associated with hyperglycemia and could be involved in the pathogenesis of type 2 diabetes mellitus.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Adult; Aged; Arginine; Blood Glucose; Carbon Isotopes; Case-Control Studies; Citrulline; Diabetes Mellitus, Type 2; Endothelial Cells; Erythrocytes; Female; Glycosylation; Hemoglobins; Hemolysis; Humans; Hyperglycemia; Male; Malondialdehyde; Metabolic Networks and Pathways; Middle Aged; Models, Biological; Nitric Oxide; Nitrites; Ornithine; Oxidative Stress; Urea

2013
α-Tocopherol administration blocks adaptive changes in cell NADH/NAD+ redox state and mitochondrial function leading to inhibition of gastric mucosa cell proliferation in rats.
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Adaptation, Physiological; alpha-Tocopherol; Animals; Antioxidants; bcl-2-Associated X Protein; Cell Proliferation; Citrulline; Drug Evaluation, Preclinical; Gastric Mucosa; Gastritis; Glucose; Male; NAD; Nitrites; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Rats, Wistar

2013
Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis.
    Antioxidants & redox signaling, 2015, Aug-01, Volume: 23, Issue:4

    Topics: Animals; Aorta; Arginine; Blood Pressure; Cardiovascular System; Citrulline; Dietary Supplements; Homeostasis; Male; Metabolic Networks and Pathways; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Phosphorylation; Rats, Sprague-Dawley

2015
Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Animals; Arginase; Arginine; Cell Count; Citrulline; Cytokines; Endotoxemia; Integrases; Jejunum; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Organ Specificity; Ornithine; Perfusion; Peroxidase; Receptor, TIE-2; RNA, Messenger

2014
Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation.
    American journal of physiology. Renal physiology, 2014, Dec-01, Volume: 307, Issue:11

    Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Fibronectins; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred DBA; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Tumor Necrosis Factor-alpha

2014
Effects of hyperbaric oxygen on nitric oxide generation in humans.
    Nitric oxide : biology and chemistry, 2015, Jan-30, Volume: 44

    Topics: Adult; Arginine; Breath Tests; Citrulline; Cyclic GMP; Humans; Hyperbaric Oxygenation; Nitrates; Nitric Oxide; Nitrites; Oxygen; Saliva; Tongue; Young Adult

2015
Plasma kallikrein-bradykinin pathway promotes circulatory nitric oxide metabolite availability during hypoxia.
    Nitric oxide : biology and chemistry, 2016, 05-01, Volume: 55-56

    Topics: Acclimatization; Adult; Altitude; Angiotensinogen; Arginine; Bradykinin; Citrulline; Humans; Hypoxia; Isoprostanes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Oxidative Stress; Plasma Kallikrein; Protein Carbonylation; Proteome; Signal Transduction

2016
Participation of oleic acid in the formation of the aortic aneurysm in Marfan syndrome patients.
    Prostaglandins & other lipid mediators, 2016, Volume: 123

    Topics: Adult; Aorta; Aortic Aneurysm; Arachidonic Acid; Case-Control Studies; Cholesterol, HDL; Citrulline; Collagen; Female; Gene Expression Regulation; Humans; Male; Marfan Syndrome; Middle Aged; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oleic Acid; Prospective Studies; Signal Transduction; Stearoyl-CoA Desaturase; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2016
The Effect Of NO Donor on Calcium Uptake and Reactive Nitrogen Species Production in Mitochondria.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:1

    Topics: Animals; Biological Transport; Calcium; Citrulline; Dose-Response Relationship, Drug; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroglycerin; Rats, Wistar; Reactive Nitrogen Species; S-Nitrosothiols

2016
Two weeks of watermelon juice supplementation improves nitric oxide bioavailability but not endurance exercise performance in humans.
    Nitric oxide : biology and chemistry, 2016, 09-30, Volume: 59

    Topics: Arginine; Arterial Pressure; Blood Glucose; Citrulline; Citrullus; Dietary Supplements; Fruit and Vegetable Juices; Heart Rate; Humans; Lactic Acid; Male; Malus; Nitric Oxide; Nitrites; Oxygen Consumption; Physical Endurance; Pulmonary Gas Exchange; Young Adult

2016
Experience of correcting endothelial dysfunction in children-residents of radioactively contaminated areas by nitric oxide potential donator citrulline.
    Problemy radiatsiinoi medytsyny ta radiobiolohii, 2017, Volume: 22

    Topics: Arginine; Bronchial Spasm; Cardiovascular Diseases; Chernobyl Nuclear Accident; Child; Citrulline; Endothelium, Vascular; Female; Humans; Immunity, Cellular; Immunity, Humoral; Lipid Peroxidation; Malates; Male; Nitric Oxide; Nitric Oxide Donors; Nitrites; Radiation Dosage; Radiation Exposure; Radioactive Pollutants; Rural Population; Survivors; T-Lymphocytes; Ukraine; Urban Population

2017
Exogenous l-ARGININE does not stimulate production OF NO or cGMP within the rat corporal smooth muscle cells in culture.
    Nitric oxide : biology and chemistry, 2019, 08-01, Volume: 89

    Topics: Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Male; Muscle, Smooth; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Penis; Phosphodiesterase 5 Inhibitors; Rats, Sprague-Dawley

2019