nitrites has been researched along with citrulline in 152 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (6.58) | 18.7374 |
| 1990's | 62 (40.79) | 18.2507 |
| 2000's | 53 (34.87) | 29.6817 |
| 2010's | 25 (16.45) | 24.3611 |
| 2020's | 2 (1.32) | 2.80 |
| Authors | Studies |
|---|---|
| Bult, H; Herman, AG; Jorens, PG; van Overveld, FJ; Vermeire, PA | 1 |
| Hishikawa, K; Kato, R; Nakaki, T; Saruta, T; Suzuki, H | 1 |
| Bult, H; Devreese, AM; Herman, AG; Jorens, PG; Marescau, B; Rosseneu, M | 1 |
| Bassetti, S; Keist, R; Keller, R; Klauser, S; Mülsch, A | 1 |
| Flaman, JM; Henry, Y; Lepoivre, M | 1 |
| Baeblich, SE; Böhme, E; Klein, MM; Schmidt, HH; Zernikow, BC | 1 |
| Adams, LB; Hibbs, JB; Krahenbuhl, JL; Taintor, RR | 1 |
| Albina, JE; Caldwell, MD; Henry, WL; Mills, CD | 1 |
| Hibbs, JB; Taintor, RR; Vavrin, Z | 1 |
| Boudbid, H; Lepoivre, M; Petit, JF | 1 |
| Marletta, MA; Tayeh, MA | 1 |
| Billiar, TR; Curran, RD; Hofmann, K; Simmons, RL; West, MA | 1 |
| Billiar, TR; Curran, RD; Ferrari, FK; Simmons, RL; Stuehr, DJ | 1 |
| Iyengar, R; Marletta, MA; Stuehr, DJ | 1 |
| Bentz, BG; Billiar, TR; Curran, RD; Simmons, RL; Stuehr, DJ; West, MA | 1 |
| Amber, IJ; Hibbs, JB; Taintor, RR; Vavrin, Z | 1 |
| Mirvish, SS | 1 |
| Ali, AM | 1 |
| Acimovic, S; Andel, H; Függer, R; Längle, F; Mühlbacher, F; Roth, R; Steininger, R; Winkler, S | 1 |
| Massoud, R; Mollace, V; Nistico, G; Rodino, P; Rotiroti, D | 1 |
| Byam-Smith, M; Garfield, RE; Izumi, H; Yallampalli, C | 1 |
| Adcock, IM; Buttery, LD; Kwon, OJ; Moncada, S; Polak, J; Riveros-Moreno, V; Robbins, RA; Springall, DR; Warren, JB; Wilson, AJ | 1 |
| Beasley, D; Eldridge, M | 1 |
| Hevel, JM; Marletta, MA | 1 |
| Absood, A; Berisha, HI; Pakbaz, H; Said, SI | 1 |
| Marletta, MA; Pufahl, RA; Wishnok, JS | 1 |
| Chen, LY; Kone, BC; Mehta, JL; Mehta, P; Turner, P | 1 |
| Mühl, H; Pfeilschifter, J | 1 |
| Bucher, B; Busse, R; Hecker, M; Schott, C; Stoclet, JC | 1 |
| Conte, A; Ottaviani, E | 1 |
| Bosia, A; Bussolino, F; Costamagna, C; Deharo, E; Gabrielli, G; Gautret, P; Ghigo, D; Ginsburg, H; Giribaldi, G; Pescarmona, G; Todde, R; Ulliers, D | 1 |
| Hey, C; Racké, K; Wessler, I | 1 |
| Ganguly, NK; Jindal, SK; Kumar, V | 1 |
| Kolb, H; Kolb-Bachofen, V; Kröncke, KD; Rodriguez, ML | 1 |
| Adam, A; Sarih, M; Souvannavong, V | 1 |
| Corbett, JA; Currie, MG; Kasten, TP; McDaniel, ML; Misko, TP; Moore, WM; Nickols, GA; Tilton, RG; Williamson, JR | 1 |
| Lemaire, G; Petit, JF; Raddassi, K | 1 |
| Damoulis, PD; Hauschka, PV | 1 |
| Aihara, T; Ikeda, Y; Koyama, Y; Kusano, T; Muto, Y; Shiraishi, M | 1 |
| Conte, A; Franchini, A; Ottaviani, E | 1 |
| Dubois, G | 1 |
| Thiemermann, C; Wu, CC | 1 |
| Asahi, M; Fujii, J; Fujiwara, N; Kaneto, H; Seo, HG; Taniguchi, N | 1 |
| Bult, H; Herman, AG; Jorens, PG; Marescau, B; Matthys, KE; Rosseneu, M; Van Hove, CE | 1 |
| Ajami, AM; Beaumier, L; Castillo, L; Young, VR | 1 |
| Agnihotri, N; Deodhar, SD; Ganguly, NK; Wanchu, A | 1 |
| Araujo, HM; Assreuy, J; Fernandes, PD; Riveros-Moreno, V | 1 |
| Briscini, L; Carruba, MO; Nisoli, E; Tonello, C | 1 |
| Chaudhuri, G; Ignarro, LJ; Pervin, S; Rogers, NE; Singh, R | 1 |
| Ganguli, NK; Gupta, I; Pradhan, M | 1 |
| Higa, T; Hiroyasu, S; Kusano, T; Miyaguni, T; Muto, Y; Nagahama, M; Okuhama, Y; Shiraishi, M; Tomori, H | 1 |
| Abramson, SB; Amin, AR; Attur, MG; Lowenstein, CJ; Patel, RN; Thakker, GD | 1 |
| Dubey, RK; Fink, D; Imthurn, B; Keller, PJ; Lauper, U; Macas, E; Rosselli, M; Rosselli, MA | 1 |
| Locher, R; Suter, PM; Vetter, W; Weisser, B | 1 |
| Barbul, A; Schäffer, MR; Tantry, U; van Wesep, RA | 1 |
| Chou, TC; Ding, YA; Ho, ST; Li, CY; Wong, CS; Wu, CC; Yen, MH | 1 |
| Facchinetti, F; Marietta, M; Neri, I; Piccinini, F; Torelli, G; Volpe, A | 1 |
| Bansal, MP; Kang, BP; Mehta, U | 1 |
| Boucher, JL; Mansuy, D; Moali, C; Sari, MA; Stuehr, DJ | 1 |
| Bina, S; Hart, JL; Muldoon, SM; Sei, Y | 1 |
| Barthlen, W; Beger, HG; Brückner, UB; Marzinzig, E; Marzinzig, M; Morris, SM; Nussler, AK; Nussler, NC; Stadler, J | 1 |
| Chouaib, S; Dugas, B; Dugas, N; Kolb, JP; Salvucci, O | 1 |
| Bambery, P; Deodhar, SD; Khullar, M; Sud, A; Wanchu, A | 1 |
| Feinstein, DL; Regunathan, S; Reis, DJ | 1 |
| Houdijk, AP; Prins, HA; Teerlink, T; Thijs, LG; van Lambalgen, AA; van Leeuwen, PA; Wiezer, MJ | 1 |
| Dees, WL; Hiney, JK; Rettori, V; Srivastava, VK | 1 |
| Baylis, C; Schmidt, RJ; Sorkin, MI; Tracy, TS; Yokota, S | 1 |
| Ganguly, NK; Gupta, I; Gupta, SK | 1 |
| Weiske, J; Wiesner, A | 1 |
| Holm, P; Kankaanranta, H; Knowles, RG; Moilanen, E; Oja, SS | 1 |
| Folkerts, G; Hammermann, R; Hey, C; Hirschmann, J; Mössner, J; Nijkamp, FP; Racké, K; Wessler, I | 1 |
| Bambery, P; Khullar, M; Sud, A; Wanchu, A | 2 |
| Boggs, S; Huang, L; Stuehr, DJ | 1 |
| Boulmerka, A; D'Alessio, P; D'Anna, R; Dugas, B; Geromin, D; Kolb, JP; Marconi, A; Marsac, C; Zadeh, MS | 1 |
| Chen, PF; Wu, KK | 2 |
| Aberle, S; Harvey, SE; Polokoff, MA; Rubanyi, GM; Zöllner, S | 1 |
| Colasanti, M; Musci, G; Persichini, T; Polticelli, F; Venturini, G | 1 |
| Bambery, P; Bhatnagar, A; Khullar, M; Singh, S; Sud, A; Wanchu, A | 2 |
| Han, JW; Kim, SH; Lee, BG; Lee, HW; Lee, HY; Lee, KR; Zee, OP | 1 |
| Meulemans, A | 2 |
| Lepore, DA | 1 |
| Gourdon, I; Guérin, MC; Roch, P; Torreilles, J | 1 |
| Fraser, T; Li, M; Turner, SW; Wang, J; Wen, C; Whitworth, JA | 1 |
| Hrabák, A; Kahán, IL; Vercruysse, V; Vray, B | 1 |
| Devaux, Y; Grosjean, S; Kelly, RA; Meistelman, C; Mertes, PM; Seguin, C; Ungureanu-Longrois, D; Zannad, F | 1 |
| Dikshit, M; Raghavan, SA | 1 |
| Bayne, E; Duckworth, LJ; Freeman, B; Kissoon, N; Lima, JJ; Sandler, E; Sullivan, KJ; Sylvester, JE | 1 |
| González-Santiago, L; López-Ongil, S; Rodríguez-Puyol, D; Rodríguez-Puyol, M | 1 |
| Bergamini, S; Daneri, F; Iannone, A; Rota, C; Tomasi, A; Virgili, F | 1 |
| Barthwal, MK; Dikshit, M; Sharma, P | 1 |
| Cedergren, J; Forslund, T; Skogh, T; Sundqvist, T | 1 |
| Leza, JC; Lizasoaín, I; Manzanares, J; Molina, JA; Moro, MA; Oliva, JM; Ortiz, S; Pérez, S; Urigüen, L | 1 |
| Deutz, NE; Luiking, YC | 1 |
| Aldieri, E; Bosia, A; Favini, R; Ghigo, D; Massobrio, M; Revelli, A | 1 |
| Cuzzocrea, S; Ischiropoulos, H; Salvemini, D | 1 |
| Antonaci, F; Costa, A; Nappi, G; Pucci, E; Ravaglia, S; Sances, G | 1 |
| Endo, T; Hara, S; Kuriiwa, F; Kurosaki, K; Mukai, T | 1 |
| Dikshit, M; Raghavan, SA; Sharma, P | 1 |
| Franke, J; Gasslander, T; Sandstrom, P; Sundqvist, T; Svanvik, J | 1 |
| Abu-Soud, HM; Diamond, MP; Galijasevic, S; Saed, GM | 1 |
| Bhattacharyya, S; Ganguly, NK; Ghosh, S; Majumdar, S; Shant, J | 1 |
| Acosta, F; Díaz, R; Ellis, AE; Gómez, V; Padilla, D; Real, F; Ruiz de Galarreta, CM | 1 |
| Selley, ML | 1 |
| Arranz, C; Balaszczuk, AM; Costa, MA; Elesgaray, R; Loria, A | 2 |
| Alving, K; Bergström, J; Marteus, H; Mavropoulos, A; Palm, JP; Ulfgren, AK | 1 |
| Boudko, D; Dahlgren, RL; Lovell, P; Moroz, LL; Sweedler, JV | 1 |
| Bachmann, C; Boulat, O; Carrozzo, R; Dionisi-Vici, C; Emma, F; Mannucci, L; Markert, M; Rizzoni, G | 1 |
| Govindasamy, C; Nadiger, HA; Sirajudeen, KN; Swamy, M; Zakaria, AZ | 1 |
| Fukatsu, A; Funami, J; Hayashi, T; Ignarro, LJ; Iguchi, A; Juliet, PA; Matsui-Hirai, H; Miyazaki, A | 1 |
| Deutz, NE; Diederen, RM; Hendrikse, F; Kessels, AG; La Heij, EC; van Eijk, HM | 1 |
| Aguiló, A; Córdova, A; Fuentespina, E; Pons, A; Sureda, A; Tauler, P; Tur, JA | 1 |
| Boeckx, WD; Booi, D; Buurman, WA; Debats, IB; Deutz, NE; van der Hulst, RR | 1 |
| Espey, MG; Harvey-White, J; Jung, CS; Oldfield, EH; Pluta, RM; Seifert, V; Zimmermann, M | 1 |
| Gross, SS; Weissman, BA | 1 |
| Hovorková, P; Klaschka, J; Kozmiková, I; Kristofiková, Z; Majer, E; Rícný, J; Rípová, D; Zach, P | 1 |
| Bannink, M; Eggermont, AM; Fekkes, D; Hengeveld, MW; Kruit, WH; Sleijfer, S; Stoter, G; van der Holt, B; Van Gool, AR | 1 |
| Cordova, A; Ferrer, MD; Perez, G; Pons, A; Sureda, A; Tauler, P; Tur, JA | 1 |
| Chandran, G; Sirajudeen, KN; Swamy, M | 1 |
| Besson-Bard, A; Courtois, C; Dahan, J; Dobrowolska, G; Gauthier, A; Jeandroz, S; Pugin, A; Wendehenne, D | 1 |
| Annie-Jeyachristy, S; Geetha, A; Kumar, SJ; Lavanya, K; Prakash, SA; Sundaram, A; Surendran, R | 1 |
| Felipo, V; Llansola, M | 1 |
| Córdova, A; Ferrer, MD; Pérez, G; Pons, A; Sureda, A; Tur, JA | 1 |
| Brown, M; Duckworth, L; Froyen, M; Gauger, C; Kissoon, N; Murphy, S; Sandler, E; Sullivan, KJ | 1 |
| de Hoon, JN; Depré, M; Van der Schueren, BJ; Van Hecken, A; Verbesselt, R; Verbrugge, FH | 1 |
| Mittal, N; Sanyal, SN | 1 |
| Fung, HL; Mohan, S; Shin, S; Wu, CC | 1 |
| Bourdon, A; Darmaun, D; Des Robert, C; Legrand, A; Piloquet, H; Rougé, C; Rozé, JC; Vodovar, M; Voyer, M | 1 |
| Amabile, N; Cortese-Krott, MM; Heiss, C; Horn, P; Hundsdörfer, C; Kelm, M; Kröncke, KD | 1 |
| Spasić, S; Tomić, A; Zunić, G | 1 |
| Boehm, M; Cortese-Krott, MM; Gladwin, MT; Kato, GJ; Kelm, M; Kovacic, JC; Liu, VB; Noguchi, A; Raghavachari, N; Wang, X; Wood, KC | 1 |
| Busanello, EN; Grings, M; Leipnitz, G; Moura, AP; Tonin, AM; Viegas, CM; Wajner, M; Zanatta, A | 1 |
| García-García, N; Hernández-Muñoz, R; Méndez-Rodríguez, ML; Olguín-Martínez, M; Quintana-Quintana, M; Ramírez-Zamora, S; Sánchez-Sevilla, L | 1 |
| Hernández-Espinosa, DR; Hernández-Muñoz, R; Olguín-Martínez, M | 1 |
| Borniquel, S; Carlström, M; Hezel, M; Huang, L; Kishikawa, H; Liu, M; Lundberg, JO; Peleli, M; Persson, AE; Weitzberg, E; Yang, T; Zollbrecht, C | 1 |
| Briedé, JJ; Buurman, WA; de Winther, MP; Ghosh, M; Hoeksema, MA; Köhler, SE; Lamers, WH; Meesters, DM; Molin, DG; Poeze, M; van den Akker, NM; van Zandvoort, MA; Wijnands, KA | 1 |
| Awad, AS; Cooper, TK; Gao, T; Morris, SM; You, H | 1 |
| Eriksson, K; Larsson, AC; Lindholm, P; Nihlén, C; Schiffer, T; Uusijärvi, J; Weitzberg, E | 1 |
| Andre, T; McKinley-Barnard, S; Morita, M; Willoughby, DS | 1 |
| Bhargava, K; Bhaumik, G; Gangwar, A; Himashree, G; Padhy, G; Sethy, NK; Sharma, M; Singh, K | 1 |
| Aranda Fraustro, A; Guarner Lans, V; Iturriaga Hernández, AV; Pérez-Torres, I; Soto, ME; Velázquez Espejel, R; Zuñiga-Muñoz, A | 1 |
| Akopova, O; Gavenauskas, B; Kolchinskaya, L; Korkach, Y; Kotsiuruba, A; Mankovska, I; Nosar, V; Sagach, V; Serebrovska, Z | 1 |
| Bailey, SJ; Blackwell, JR; Jones, AM; Vanhatalo, A; Williams, E; Winyard, PG; Wylie, LJ | 1 |
| Kolpakov, IY; Kondrashova, VH; Kryzhanivska, VV; Leonovich, OS; Stepanova, YI; Vdovenko, VY; Zygalo, VM | 1 |
| Abraham, A; Artaza, JN; Ferrini, MG; Flores, M; Graciano, L; Luna, R; Nguyen, S; Rajfer, J | 1 |
| Keith, DS; Persky, AM; Ryan, ED; Schwartz, TA; Smith-Ryan, AE; Stoner, L; Trexler, ET | 1 |
| Azizi, S; Ebrahimi-Mameghani, M; Karamzad, N; Mahdavi, R; Mobasseri, M | 1 |
| Beckmann, B; Blau, LS; Dimina, L; Finkel, A; Jantz, M; Lützow, M; Maassen, N; Mariotti, F; Röhrig, MA; Shushakov, V; Thorns, A; Tsikas, D | 1 |
5 review(s) available for nitrites and citrulline
| Article | Year |
|---|---|
Nitric oxide: an ancestral immunocyte effector molecule.
Topics: Animals; Cardiovascular Diseases; Cell Adhesion; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Humans; Infections; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Vasodilation | 1995 |
Nitric oxide synthase-independent generation of nitric oxide in muscle ischemia--reperfusion injury.
Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Isoenzymes; Mice; Muscle, Skeletal; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Reperfusion Injury | 2000 |
Isotopic investigation of nitric oxide metabolism in disease.
Topics: Arginine; Biomarkers; Citrulline; Humans; Isotope Labeling; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes | 2003 |
Roles of nitric oxide and superoxide in inflammation.
Topics: 2-Naphthylamine; Animals; Arginine; Blotting, Western; Capillary Permeability; Chemotaxis, Leukocyte; Citrulline; Fluorescent Dyes; Fluorometry; Inflammation; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Rats; Superoxides; Tyrosine | 2003 |
Nitric oxide in plants: production and cross-talk with Ca2+ signaling.
Topics: Animals; Arabidopsis; Arginine; Calcium; Calcium-Transporting ATPases; Citrulline; Genome, Plant; Mammals; Nitrate Reductase; Nitric Oxide; Nitric Oxide Synthase; Nitriles; Nitrites; Plant Physiological Phenomena; Protein Kinases; Signal Transduction | 2008 |
12 trial(s) available for nitrites and citrulline
| Article | Year |
|---|---|
L-arginine infusion decreases platelet aggregation through an intraplatelet nitric oxide release.
Topics: Adenosine Diphosphate; Adult; Arginine; Blood Pressure; Citrulline; Collagen; Diastole; Female; Humans; Infusions, Intravenous; Nitric Oxide; Nitrites; Placebos; Platelet Aggregation; Systole; Time Factors | 1997 |
Pentoxiphylline reduces nitric oxide production among patients with HIV infection.
Topics: Adult; Citrulline; Female; HIV Infections; Humans; Male; Middle Aged; Nitric Oxide; Nitrites; Pentoxifylline; Tumor Necrosis Factor-alpha | 2000 |
Increased nitric oxide production in patients with systemic sclerosis.
Topics: Biomarkers; Citrulline; Female; Humans; Male; Multivariate Analysis; Nitric Oxide; Nitrites; Predictive Value of Tests; Scleroderma, Systemic; Severity of Illness Index; Vital Capacity | 2000 |
Effects of L-citrulline oral supplementation on polymorphonuclear neutrophils oxidative burst and nitric oxide production after exercise.
Topics: Administration, Oral; Arginine; Bicycling; Citrulline; Creatine Kinase; Dietary Supplements; DNA Damage; Double-Blind Method; Exercise; Humans; L-Lactate Dehydrogenase; Malates; Male; Malondialdehyde; Neutrophil Activation; Neutrophils; Nitric Oxide; Nitrites; Respiratory Burst; Time Factors; Young Adult | 2009 |
L-citrulline-malate influence over branched chain amino acid utilization during exercise.
Topics: Administration, Oral; Amino Acids, Branched-Chain; Arginine; Bicycling; Biomarkers; Citrulline; Creatinine; Dietary Proteins; Dietary Supplements; Double-Blind Method; Exercise; Human Growth Hormone; Humans; Insulin; Malates; Male; Muscle, Skeletal; Nitrites; Ornithine; Time Factors; Urea; Young Adult | 2010 |
Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome.
Topics: Acute Chest Syndrome; Acute Disease; Administration, Oral; Adolescent; Anemia, Sickle Cell; Arginine; Aspartic Acid; Breath Tests; Child; Citrulline; Female; Glutamic Acid; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Young Adult | 2010 |
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.
Topics: Area Under Curve; Arginine; Biomarkers; Citrulline; Cyclic GMP; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites | 2010 |
Urinary citrulline in very low birth weight preterm infants receiving intravenous nutrition.
Topics: Biomarkers; Child Development; Citrulline; Energy Intake; France; Gastrointestinal Tract; Humans; Infant Nutritional Physiological Phenomena; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Male; Multivariate Analysis; Nitrates; Nitrites; Parenteral Nutrition; Parenteral Nutrition, Total; Pilot Projects | 2012 |
Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis.
Topics: Adolescent; Adult; Animals; Arginine; Biomarkers; Body Mass Index; Citrulline; Cyclic GMP; Dietary Supplements; Double-Blind Method; Glutathione; Healthy Volunteers; Human Umbilical Vein Endothelial Cells; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Resistance Training; Young Adult | 2015 |
Effects of Citrulline Malate and Beetroot Juice Supplementation on Blood Flow, Energy Metabolism, and Performance During Maximum Effort Leg Extension Exercise.
Topics: Adolescent; Adult; Beta vulgaris; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Energy Metabolism; Exercise; Femoral Artery; Fruit and Vegetable Juices; Humans; Malates; Male; Nitrates; Nitrites; Performance-Enhancing Substances; Plant Roots; Quadriceps Muscle; Regional Blood Flow; Ultrasonography; Young Adult | 2019 |
Oxidative stress and nitrate/nitrite (NOx) status following citrulline supplementation in type 2 diabetes: a randomised, double-blind, placebo-controlled trial.
Topics: Adult; Antioxidants; Blood Glucose; Citrulline; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Glutathione Peroxidase; Humans; Iran; Male; Malondialdehyde; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Superoxide Dismutase | 2021 |
Short-Term Supplementation of Sodium Nitrate vs. Sodium Chloride Increases Homoarginine Synthesis in Young Men Independent of Exercise.
Topics: Arginine; Citrulline; Creatine; Creatinine; Dietary Supplements; Glutamates; Glutamine; Glycine; Homoarginine; Humans; Lysine; Male; Malondialdehyde; Methyltransferases; Nitrates; Nitrites; Ornithine; Phenylalanine; Sarcosine; Sodium Chloride; Tryptophan; Tyrosine | 2022 |
135 other study(ies) available for nitrites and citrulline
| Article | Year |
|---|---|
Pterins inhibit nitric oxide synthase activity in rat alveolar macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Cells, Cultured; Citrulline; Hypoxanthines; Interferon-gamma; Macrophages, Alveolar; Male; Nitric Oxide Synthase; Nitrites; Pteridines; Pterins; Rats; Rats, Wistar; Recombinant Proteins | 1992 |
L-arginine as an antihypertensive agent.
Topics: Antihypertensive Agents; Arginine; Blood Pressure; Cardiac Output; Citrulline; Cushing Syndrome; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Injections, Intravenous; Nitrates; Nitrites | 1992 |
Diminished capacity to release metabolites of nitric oxide synthase in macrophages loaded with oxidized low-density lipoproteins.
Topics: Amino Acid Oxidoreductases; Animals; Cell Line; Cholesterol; Citrulline; Foam Cells; Interferon-gamma; Lipopolysaccharides; Lipoproteins, LDL; Macrophages; Mice; Nitric Oxide Synthase; Nitrites; Recombinant Proteins | 1992 |
Induction of nitric oxide synthase is a necessary precondition for expression of tumor necrosis factor-independent tumoricidal activity by activated macrophages.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bone Marrow; Cell Line; Cell Survival; Cells, Cultured; Citrulline; Drug Resistance; Enterococcus faecalis; Escherichia coli; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mast-Cell Sarcoma; Moraxella catarrhalis; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Onium Compounds; Peptidoglycan; Phagocytes; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 1992 |
Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide.
Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Western; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Induction; Free Radicals; Kinetics; Mammary Neoplasms, Experimental; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Ribonucleotide Reductases; Tumor Cells, Cultured; Tyrosine | 1992 |
L-arginine and arginine analogues: effects on isolated blood vessels and cultured endothelial cells.
Topics: Animals; Arginine; Cattle; Citrulline; Endothelium, Vascular; Guanethidine; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Inbred Strains; Stereoisomerism; Swine | 1990 |
Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine.
Topics: Animals; Arginine; Citrulline; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitrates; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Toxoplasma | 1990 |
Temporal expression of different pathways of 1-arginine metabolism in healing wounds.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Citrulline; Hydrolases; In Vitro Techniques; Macrophages; Male; Neutrophils; Nitrites; Ornithine; Rats; Urea; Wound Healing | 1990 |
Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite.
Topics: Ammonia; Animals; Cells, Cultured; Citrulline; Cytotoxicity, Immunologic; Homoarginine; Hydrolases; Macrophage Activation; Macrophages; Mice; Nitrates; Nitrites | 1987 |
Antiproliferative activity of gamma-interferon combined with lipopolysaccharide on murine adenocarcinoma: dependence on an L-arginine metabolism with production of nitrite and citrulline.
Topics: Adenocarcinoma; Animals; Arginine; Cell Division; Citrulline; Interferon-gamma; Kinetics; Lipopolysaccharides; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nitrites; Recombinant Proteins; Tumor Cells, Cultured | 1989 |
Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor.
Topics: Animals; Arginine; Biopterins; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Kinetics; Macrophages; NADP; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction | 1989 |
Kupffer cell cytotoxicity to hepatocytes in coculture requires L-arginine.
Topics: Animals; Arginine; Aspartate Aminotransferases; Cell Survival; Cells, Cultured; Citrulline; Infections; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; omega-N-Methylarginine; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1989 |
Evidence that activation of Kupffer cells results in production of L-arginine metabolites that release cell-associated iron and inhibit hepatocyte protein synthesis.
Topics: Animals; Arginine; Citrulline; Culture Media; Iron; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; Protein Biosynthesis; Proteins; Rats | 1989 |
Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst.
Topics: Arginine; Citrulline; Humans; Hydrogen Peroxide; Macrophage Activation; Macrophages; Morpholines; Nitrates; Nitrites; Nitrosamines; Superoxides | 1987 |
An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro.
Topics: Animals; Arginine; Citrulline; In Vitro Techniques; Kupffer Cells; Lipopolysaccharides; Liver; Nitrates; Nitrites; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1989 |
Cytokines induce an L-arginine-dependent effector system in nonmacrophage cells.
Topics: Animals; Arginine; Biological Products; Citrulline; Cytokines; Humans; Lipopolysaccharides; Mammary Neoplasms, Experimental; Nitrates; Nitrites; Tumor Cells, Cultured; Urea | 1988 |
Kinetics of nitrosamide formation from alkylureas, N-alkylurethans, and alkylguanidines: possible implications for the etiology of human gastric cancer.
Topics: Arginine; Carcinogens; Chemical Phenomena; Chemistry; Citrulline; Diet; Guanidines; Humans; Kinetics; Nitrites; Nitroso Compounds; Nitrosoguanidines; Nitrosourea Compounds; Sodium; Spectrophotometry; Stomach Neoplasms; Urea; Urethane | 1971 |
Biochemical characterization of arginine muants in Schizosaccharomyces pombe and the possibility of repression.
Topics: Arginine; Ascomycota; Citrulline; Culture Media; Enzyme Repression; Mutation; Neurospora; Nitrites; Ornithine; Proline; Radiation Genetics; Succinates | 1967 |
L-arginine deficiency and hemodynamic changes as a result of arginase efflux following orthotopic liver transplantation.
Topics: Adult; Arginase; Arginine; Blood Pressure; Citrulline; Diastole; Female; Humans; Liver Transplantation; Male; Monitoring, Intraoperative; Nitrates; Nitrites; Ornithine; Pulmonary Wedge Pressure; Reperfusion | 1995 |
Age-dependent changes of NO synthase activity in the rat brain.
Topics: Aging; Animals; Brain; Brain Stem; Calcium; Cerebellum; Citrulline; Frontal Lobe; Hippocampus; In Vitro Techniques; Male; Nitric Oxide Synthase; Nitrites; Organ Specificity; Parietal Lobe; Rats; Rats, Wistar | 1995 |
An L-arginine-nitric oxide-cyclic guanosine monophosphate system exists in the uterus and inhibits contractility during pregnancy.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Culture Techniques; Cyclic GMP; Dose-Response Relationship, Drug; Female; Labor, Obstetric; Methylene Blue; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley; Uterine Contraction; Uterus | 1994 |
Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimulation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Epithelium; Guanidines; Interferon-gamma; Interleukin-1; Kinetics; Lung; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Recombinant Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha | 1994 |
Interleukin-1 beta and tumor necrosis factor-alpha synergistically induce NO synthase in rat vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Cells, Cultured; Citrulline; Cyclic GMP; Drug Synergism; Enzyme Induction; Gene Expression; Interleukin-1; Lipopolysaccharides; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitrites; Rats; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Nitric-oxide synthase assays.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chromatography, Ion Exchange; Citrulline; Dithiothreitol; Hemoglobins; Indicators and Reagents; Mammals; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Pterins; Sensitivity and Specificity; Spectrophotometry | 1994 |
Nitric oxide as a mediator of oxidant lung injury due to paraquat.
Topics: Amino Acid Oxidoreductases; Animals; Calcium; Citrulline; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidants; Paraquat; Perfusion; Respiration | 1994 |
Hydrogen peroxide-supported oxidation of NG-hydroxy-L-arginine by nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Benzene Derivatives; Cell Line; Citrulline; Hydrogen Peroxide; Kinetics; Macrophages; Mice; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Oxygen; Peroxides; tert-Butylhydroperoxide | 1995 |
Identification of constitutive and inducible forms of nitric oxide synthase in human platelets.
Topics: Amino Acid Oxidoreductases; Arginine; Blood Platelets; Citrulline; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Humans; Nitric Oxide Synthase; Nitrites; Nitroarginine; Platelet Aggregation; Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 1995 |
Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta-stimulated rat mesangial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Northern; Cell Nucleus; Citrulline; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transcription, Genetic | 1995 |
Increase in serum NG-hydroxy-L-arginine in rats treated with bacterial lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Escherichia coli; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Stereoisomerism | 1995 |
Nitric oxide synthase activity in molluscan hemocytes.
Topics: Amino Acid Oxidoreductases; Animals; Antibodies; Arginine; Citrulline; Hemocytes; Kinetics; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rabbits; Snails | 1995 |
Erythrocyte stages of Plasmodium falciparum exhibit a high nitric oxide synthase (NOS) activity and release an NOS-inducing soluble factor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Factors; Canavanine; Cell Adhesion; Cells, Cultured; Citrulline; Culture Media, Conditioned; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Erythrocytes; Host-Parasite Interactions; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Plasmodium; Plasmodium falciparum; Protozoan Proteins; Species Specificity; Umbilical Veins | 1995 |
Nitric oxide synthase activity is inducible in rat, but not rabbit alveolar macrophages, with a concomitant reduction in arginase activity.
Topics: Amino Acid Oxidoreductases; Animals; Arginase; Arginine; Citrulline; Cytokines; Dexamethasone; Enzyme Induction; Female; In Vitro Techniques; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Rabbits; Rats; Rats, Sprague-Dawley | 1995 |
Release of reactive oxygen and nitrogen intermediates from monocytes of patients with pulmonary tuberculosis.
Topics: Adolescent; Adult; Citrulline; Electron Transport; Female; Follow-Up Studies; Humans; Macrophages; Male; Middle Aged; Monocytes; Nitrites; Nitrogen Compounds; Reactive Oxygen Species; Tuberculosis, Pulmonary | 1995 |
Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Female; Islets of Langerhans; Kinetics; Macrophage Activation; Macrophages; Male; Nitric Oxide; Nitrites; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar; Thionucleotides | 1993 |
Nitric oxide synthase induces macrophage death by apoptosis.
Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Cells, Cultured; Citrulline; Female; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Nitric Oxide Synthase; Nitrites | 1993 |
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Guanidines; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1993 |
LPS-induced activation of primed murine peritoneal macrophages is modulated by prostaglandins and cyclic nucleotides.
Topics: Amino Acid Oxidoreductases; Animals; Cell Division; Citrulline; Cord Factors; Cyclic AMP; Indomethacin; Lipopolysaccharides; Macrophage Activation; Mice; Nitric Oxide Synthase; Nitrites; Prostaglandins; Tumor Cells, Cultured | 1993 |
Cytokines induce nitric oxide production in mouse osteoblasts.
Topics: 3T3 Cells; Animals; Arginine; Cell Line; Cell Survival; Citrulline; Cycloheximide; Cytokines; Dactinomycin; Dexamethasone; Egtazic Acid; Escherichia coli; Humans; Indomethacin; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Osteoblasts; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Protection against hepatic ischemia/reperfusion injury by exogenous L-arginine.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Liver; Liver Circulation; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury | 1996 |
Decreased L-arginine-nitric oxide pathway in cultured myoblasts from spontaneously hypertensive versus normotensive Wistar-Kyoto rats.
Topics: Animals; Cell Division; Cells, Cultured; Citrulline; Culture Media; Mitosis; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred SHR; Rats, Wistar | 1996 |
Biological control and inhibition of induction of nitric oxide synthase.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Line; Citrulline; Colorimetry; Enzyme Induction; Ethylenediamines; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Lung; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Radioisotope Dilution Technique; Rats; RNA, Messenger; Signal Transduction; Sulfanilamides; Transcription, Genetic; Tritium | 1996 |
Effect of a nitric oxide synthase inhibitor, S-ethylisothiourea, on cultured cells and cardiovascular functions of normal and lipopolysaccharide-treated rabbits.
Topics: Animals; Blood Pressure; Brain; Cells, Cultured; Citrulline; Colforsin; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Interleukin-1; Isothiuronium; L-Lactate Dehydrogenase; Lipopolysaccharides; Nitric Oxide Synthase; Nitrites; Nucleosomes; Rabbits; Rats; Shock, Septic | 1996 |
Dual effects of oxidized low-density lipoprotein on immune-stimulated nitric oxide and prostaglandin release in macrophages.
Topics: Animals; Cells, Cultured; Citrulline; Indomethacin; Interferon-gamma; Lipopolysaccharides; Lipoproteins, LDL; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Prostaglandins | 1996 |
Whole body nitric oxide synthesis in healthy men determined from [15N] arginine-to-[15N]citrulline labeling.
Topics: Adult; Arginine; Citrulline; Eating; Fasting; Humans; Isotope Labeling; Male; Models, Biological; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes; Time Factors | 1996 |
Plasma reactive nitrogen intermediate levels in patients with clinically active rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Citrulline; Female; Free Radicals; Humans; Male; Methotrexate; Nitrites; Nitrogen | 1996 |
Depolymerization of macrophage microfilaments prevents induction and inhibits activity of nitric oxide synthase.
Topics: Actin Cytoskeleton; Amino Acid Sequence; Animals; Cells, Cultured; Citrulline; Colchicine; Cytochalasin B; Enzyme Induction; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nitric Oxide Synthase; Nitrites; Recombinant Proteins | 1996 |
Inducible nitric oxide synthase in rat brown adipocytes: implications for blood flow to brown adipose tissue.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Arginine; Cells, Cultured; Citrulline; Dactinomycin; Enzyme Induction; Enzyme Inhibitors; Kinetics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Norepinephrine; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1997 |
Evidence for the presence of an unusual nitric oxide- and citrulline-producing enzyme in rat kidney.
Topics: Animals; Calcium; Calmodulin; Citrulline; Enzyme Inhibitors; Female; Guinea Pigs; Isoenzymes; Isothiuronium; Kidney; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pregnancy; Rats; Rats, Sprague-Dawley; Sepharose | 1997 |
Nitrites and L-citrulline levels in copper intrauterine device users.
Topics: Citrulline; Female; Humans; Intrauterine Devices, Copper; Leukocytes, Mononuclear; Nitric Oxide; Nitrites; Superoxides; Uterus | 1997 |
Role of exogenous L-arginine in hepatic ischemia-reperfusion injury.
Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Citrulline; Cyclic GMP; Female; Hemodynamics; Liver; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Reperfusion Injury; Swine; Time Factors | 1997 |
Post-transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines.
Topics: Animals; Arginine; Citrulline; Doxycycline; Hydrocortisone; Macrophages; Mice; Minocycline; Molecular Structure; Nitric Oxide Synthase; Nitrites; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetracyclines | 1997 |
Identification of nitric oxide synthase in human and bovine oviduct.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Citrulline; Epithelial Cells; Epithelium; Fallopian Tubes; Female; Humans; In Vitro Techniques; NADPH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitrites | 1996 |
Low-density lipoprotein-induced formation of nitric oxide by cultured vascular smooth muscle cells of the rat.
Topics: Animals; Cells, Cultured; Citrulline; Cyclic GMP; Female; Humans; Lipoproteins, LDL; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Thymidine | 1997 |
Nitric oxide metabolism in wounds.
Topics: Animals; Citrulline; Enzyme Induction; Macrophages; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Nitrites; Ornithine; Skin; Time Factors; Wound Healing | 1997 |
Ketamine inhibits nitric oxide synthase in lipopolysaccharide-treated rat alveolar macrophages.
Topics: Analysis of Variance; Anesthetics, Dissociative; Animals; Arginine; Blotting, Western; Cell Respiration; Cell Survival; Cells, Cultured; Citrulline; Culture Media; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Enzymologic; Ketamine; Lipopolysaccharides; Macrophages, Alveolar; Male; Nitric Oxide Synthase; Nitrites; Radiopharmaceuticals; Rats; Rats, Inbred WKY; Tritium; Tumor Necrosis Factor-alpha | 1997 |
Effect of diet induced hypercholesterolemia and selenium supplementation on nitric oxide synthase activity.
Topics: Animals; Antioxidants; Cholesterol; Cholesterol, Dietary; Citrulline; Enzyme Induction; Hypercholesterolemia; Male; Nitric Oxide Synthase; Nitrites; Rabbits; Selenium; Triglycerides | 1997 |
Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine.
Topics: Animals; Arginine; Catalysis; Cattle; Citrulline; Homoarginine; Kinetics; NADP; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Oxygen; Substrate Specificity | 1998 |
Factors contributing to differences in the regulation of cGMP in isolated porcine pulmonary vessels.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blotting, Western; Carbon Radioisotopes; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate Cyclase; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Pulmonary Veins; Purinones; Swine | 1998 |
Improved methods to measure end products of nitric oxide in biological fluids: nitrite, nitrate, and S-nitrosothiols.
Topics: Body Fluids; Chromatography, Ion Exchange; Citrulline; Humans; Mercaptoethanol; Nitrates; Nitric Oxide; Nitrites; Nitroso Compounds; S-Nitrosothiols; Tumor Cells, Cultured | 1997 |
The induction of nitric oxide by interleukin-12 and tumor necrosis factor-alpha in human natural killer cells: relationship with the regulation of lytic activity.
Topics: Adjuvants, Immunologic; Antibodies; Cells, Cultured; Citrulline; Cytotoxicity, Immunologic; Drug Synergism; Enzyme Induction; Granzymes; Guanidines; Humans; Interferon-gamma; Interleukin-12; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lymphocyte Activation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitroprusside; Serine Endopeptidases; Tumor Necrosis Factor-alpha | 1998 |
Nitric oxide synthesis is increased in patients with systemic lupus erythematosus.
Topics: Adolescent; Adult; Analysis of Variance; Citrulline; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Nitric Oxide; Nitrites; Spectrophotometry | 1998 |
Inhibition of astroglial nitric oxide synthase type 2 expression by idazoxan.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Arginine; Astrocytes; Cell Line; Cell-Free System; Chloramphenicol O-Acetyltransferase; Citrulline; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Idazoxan; Lipopolysaccharides; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Norepinephrine; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 1999 |
Reduced arginine plasma levels are the drive for arginine production by the kidney in the rat.
Topics: Animals; Arginase; Arginine; Blood Chemical Analysis; Cattle; Citrulline; Digestive System; Endotoxemia; Kidney; Liver; Male; Nitrates; Nitrites; Ornithine; Rats; Rats, Wistar; Regional Blood Flow | 1999 |
Effects of ethanol on intraovarian nitric oxide production in the prepubertal rat.
Topics: Animals; Arginine; Blotting, Western; Citrulline; Estradiol; Ethanol; Female; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ovary; Rats; Rats, Sprague-Dawley; Sexual Maturation | 1999 |
Nitric oxide production is low in end-stage renal disease patients on peritoneal dialysis.
Topics: Adult; Aged; Arginine; Citrulline; Creatinine; Cyclic GMP; Female; Humans; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Peritoneal Dialysis | 1999 |
Reactive oxygen intermediates and reactive nitrogen intermediates in copper intrauterine device users.
Topics: Chromogenic Compounds; Citrulline; Ethylenediamines; Female; Free Radical Scavengers; Humans; Intrauterine Devices, Copper; Luminescent Measurements; Monocytes; Nitrites; Reactive Oxygen Species; Scintillation Counting; Sulfanilamides; Uterus | 1999 |
Stimulation of NO synthase activity in the immune-competent lepidopteran Estigmene acraea hemocyte line.
Topics: Animals; Arginine; Cell Line; Citrulline; Enzyme Activation; Enzyme Inhibitors; Hemocytes; Immunocompetence; Kinetics; Lepidoptera; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Superoxide Dismutase | 1999 |
No detectable NO synthesis from L-arginine or N(G)-hydroxy-L-arginine in fMLP-stimulated human blood neutrophils despite production of nitrite, nitrate, and citrulline from N(G)-hydroxy-L-arginine.
Topics: Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitroarginine | 1999 |
Cationic proteins inhibit L-arginine uptake in rat alveolar macrophages and tracheal epithelial cells. Implications for nitric oxide synthesis.
Topics: Animals; Arginase; Arginine; Blood Proteins; Citrulline; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Epithelial Cells; Female; Fibrinolytic Agents; Gene Expression; Heparin; Lipopolysaccharides; Lung; Lysine; Macrophages, Alveolar; Male; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Ribonucleases; Time Factors; Trachea | 1999 |
Nitric oxide production is increased in patients with inflammatory myositis.
Topics: Adolescent; Adult; Biomarkers; Citrulline; Dermatomyositis; Female; Humans; Inflammation; Male; Methotrexate; Middle Aged; Nitric Oxide; Nitrites; Polymyositis; Prednisolone; Reference Values | 1999 |
Formation and reactions of the heme-dioxygen intermediate in the first and second steps of nitric oxide synthesis as studied by stopped-flow spectroscopy under single-turnover conditions.
Topics: Animals; Arginine; Catalysis; Citrulline; Ferrous Compounds; Heme; Kinetics; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Oxygen; Rats; Spectrophotometry | 2000 |
Regulation of ICAM-1/CD54 expression on human endothelial cells by hydrogen peroxide involves inducible NO synthase.
Topics: Cells, Cultured; Citrulline; Drug Synergism; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-1; Isoenzymes; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer.
Topics: Amino Acid Sequence; Animals; Calcium; Calmodulin; Catalysis; Cell Line; Citrulline; Dose-Response Relationship, Drug; Electron Transport; Escherichia coli; Humans; Insecta; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis; NADH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Protein Binding; Sequence Homology, Amino Acid | 2000 |
Changes of endothelial nitric oxide synthase level and activity during endothelial cell proliferation.
Topics: Animals; Arginine; Cattle; Cell Division; Cells, Cultured; Citrulline; Endothelium, Vascular; Kinetics; Luminescent Measurements; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Superoxide Dismutase; Superoxides | 2000 |
Modulation of the nitric oxide pathway by copper in glial cells.
Topics: Animals; Arginine; Citrulline; Copper; Cyclic GMP; Gene Expression Regulation, Enzymologic; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Neuroglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Rats; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Suppression of inducible nitric oxide synthase expression in RAW 264. 7 macrophages by two beta-carboline alkaloids extracted from Melia azedarach.
Topics: Alkaloids; Animals; Carbolines; Cell Line; Citrulline; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin-Endoperoxide Synthases | 2000 |
Electrochemical detection of nitroso-arginine as an intermediate between N-hydroxy-arginine and citrulline. An in vitro versus in vivo study using microcarbon electrodes in neuronal nitric oxide synthase and mice brain.
Topics: Animals; Arginine; Brain; Brain Chemistry; Citrulline; Electrochemistry; Mice; Microelectrodes; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Nitroso Compounds; Oxidation-Reduction; Surface Properties | 2000 |
Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis.
Topics: Animals; Arginine; Bivalvia; Citrulline; Enzyme Inhibitors; Hemocytes; Latex; Luminescent Measurements; Microspheres; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Phagocytosis; Superoxide Dismutase; Superoxides | 2001 |
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Arginine; Citrulline; Cyclic GMP; Drug Evaluation; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2000 |
Indomethacin prevents the induction of inducible nitric oxide synthase in murine peritoneal macrophages and decreases their nitric oxide production.
Topics: Animals; Arginase; Arginine; Blotting, Western; Citrulline; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Indomethacin; Macrophages, Peritoneal; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Uridine | 2001 |
Retinoic acid attenuates inducible nitric oxide synthase (NOS2) activation in cultured rat cardiac myocytes and microvascular endothelial cells.
Topics: Animals; Arginine; Blotting, Northern; Blotting, Western; Cells, Cultured; Citrulline; Dactinomycin; Endothelium, Vascular; Enzyme Activation; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Macrophages, Alveolar; Male; Microcirculation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Tretinoin | 2001 |
L-citrulline mediated relaxation in the control and lipopolysaccharide-treated rat aortic rings.
Topics: Animals; Aorta; Arginine; Citrulline; Corticosterone; Cyclic GMP; Cycloheximide; Glutamine; Guanidines; In Vitro Techniques; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilation | 2001 |
Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome.
Topics: Acute Disease; Adolescent; Anemia, Sickle Cell; Arginine; Breath Tests; Child; Citrulline; Forced Expiratory Volume; Genotype; Humans; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Polymorphism, Genetic; Syndrome; Trinucleotide Repeats; Vital Capacity | 2001 |
A brain nitric oxide synthase study in the rat: production of a nitroso-compound NA and absence of nitric oxide synthesis.
Topics: Animals; Arginine; Brain; Citrulline; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nitroso Compounds; Rats | 2002 |
Decreased nitric oxide synthesis in human endothelial cells cultured on type I collagen.
Topics: Cells, Cultured; Citrulline; Collagen Type I; Endothelium, Vascular; Humans; Integrins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Peptides; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; RNA, Messenger; Signal Transduction | 2002 |
N-Acetylcysteine negatively modulates nitric oxide production in endotoxin-treated rats through inhibition of NF-kappaB activation.
Topics: Acetylcysteine; Animals; Citrulline; DNA; Endotoxins; Enzyme Activation; Free Radical Scavengers; Lipopolysaccharides; Male; NF-kappa B; Nitrates; Nitric Oxide; Nitrites; Protein Binding; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2002 |
Antitubercular therapy decreases nitric oxide production in HIV/TB coinfected patients.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Biomarkers; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Citrulline; Drug Administration Schedule; Enzyme Inhibitors; Ethambutol; Female; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Mycobacterium; Nitric Oxide; Nitrites; Pyrazinamide; Rifampin; T-Lymphocyte Subsets; Tuberculosis | 2002 |
NO synthesis and its regulation in the arachidonic-acid-stimulated rat polymorphonuclear leukocytes.
Topics: Animals; Arachidonic Acid; Calcium; Calmodulin; Citrulline; Free Radical Scavengers; Free Radicals; Hyperoxia; Neutrophils; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2002 |
Inducible nitric oxide synthase is expressed in synovial fluid granulocytes.
Topics: Adult; Aged; Arginine; Arthritis, Rheumatoid; Autoimmune Diseases; Blood Cells; Chromatography, High Pressure Liquid; Citrulline; Colorimetry; Enzyme Induction; Exudates and Transudates; Female; Granulocytes; Humans; Knee; Male; Membrane Proteins; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Organ Specificity; Synovial Fluid | 2002 |
Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites are increased in dementia with Lewy bodies.
Topics: Aged; Arginine; Citrulline; Female; Humans; Lewy Body Disease; Male; Nitrates; Nitrites | 2002 |
Nitric oxide synthesis in human nonpregnant myometrium and uterine myomas.
Topics: Adult; Citrulline; Estradiol; Female; Humans; Middle Aged; Myoma; Myometrium; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Progesterone; Prospective Studies; Tumor Cells, Cultured; Uterine Neoplasms | 2003 |
Nitric oxide pathway and response to nitroglycerin in cluster headache patients: plasma nitrite and citrulline levels.
Topics: Adult; Analysis of Variance; Citrulline; Cluster Headache; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitrites; Nitroglycerin; Signal Transduction | 2003 |
Characterization of suppression of nitric oxide production by carbon monoxide poisoning in the striatum of free-moving rats, as determined by in vivo brain microdialysis.
Topics: Animals; Arginine; Carbon Monoxide Poisoning; Citrulline; Corpus Striatum; Extracellular Space; Isomerism; Male; Microdialysis; Movement; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley | 2003 |
Role of ascorbate in the regulation of nitric oxide generation by polymorphonuclear leukocytes.
Topics: Animals; Ascorbic Acid; Biopterins; Blood Platelets; Citrulline; Dehydroascorbic Acid; Flow Cytometry; Haplorhini; Humans; Iodoacetamide; Male; Neutrophils; Nitric Oxide; Nitrites; Oxidation-Reduction; Oxygen; Rats; Rats, Sprague-Dawley | 2003 |
Depletion of serum L-arginine in patients with acute pancreatitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Alcoholism; Amylases; Arginine; C-Reactive Protein; Cholecystitis, Acute; Citrulline; Female; Gallstones; Humans; Male; Middle Aged; Nitrates; Nitrites; Pancreatitis; Pancreatitis, Alcoholic; Recurrence; Time Factors | 2003 |
Structural elements contribute to the calcium/calmodulin dependence on enzyme activation in human endothelial nitric-oxide synthase.
Topics: Amino Acid Sequence; Animals; Baculoviridae; Calcium; Calmodulin; Catalysis; Chelating Agents; Citrulline; Culture Media; Cytochromes c; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Ferricyanides; Gene Deletion; Humans; Insecta; Molecular Sequence Data; Mutation; NADP; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oxygen; Protein Structure, Tertiary; Sequence Homology, Amino Acid | 2003 |
Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition.
Topics: Animals; Arginine; Catalysis; Chromatography, High Pressure Liquid; Citrulline; Electrochemistry; Escherichia coli; Feedback, Physiological; Hydrogen Peroxide; Inflammation; Kinetics; Mice; Milk; Models, Biological; Models, Chemical; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxygen; Peroxidase; Protein Binding; RNA, Messenger; Spectrophotometry; Time Factors; Ultraviolet Rays; Up-Regulation | 2003 |
Role of the W07-toxin on Vibrio cholerae-induced diarrhoea.
Topics: Animals; Bacterial Toxins; Calcium; Catalase; Cells, Cultured; Citrulline; Diarrhea; Disease Models, Animal; Dose-Response Relationship, Drug; Enterocytes; Inositol Phosphates; Intestine, Small; Luminescent Measurements; Mice; Mice, Inbred BALB C; Nitrites; Phospholipase C gamma; Protein Kinase C; Signal Transduction; Time Factors; Type C Phospholipases; Vibrio cholerae | 2004 |
Activation of the nitric oxide response in gilthead seabream after experimental infection with Photobacterium damselae subsp. piscicida.
Topics: Analysis of Variance; Animals; Bacterial Capsules; Body Constitution; Citrulline; Fish Diseases; Glucose; Gram-Negative Bacterial Infections; Lethal Dose 50; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Photobacterium; Sea Bream; Time Factors; Virulence | 2004 |
Increased (E)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression.
Topics: Aldehydes; Arginine; Citrulline; Coronary Disease; Depressive Disorder, Major; Female; Glutathione; Humans; Lipid Peroxidation; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites | 2004 |
Role of nitric oxide pathway in hypotensive and renal effects of furosemide during extracellular volume expansion.
Topics: Animals; Blood Pressure; Blood Volume; Carbon Radioisotopes; Citrulline; Diuresis; Diuretics; Extracellular Fluid; Furosemide; Hypotension; Kidney; Male; NADPH Dehydrogenase; Natriuresis; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Renal Circulation | 2004 |
Nitric oxide formation in the oropharyngeal tract: possible influence of cigarette smoking.
Topics: Adult; Aged; Biopsy; Citrulline; Humans; Immunohistochemistry; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Oropharynx; Saliva; Smoking | 2004 |
Direct single cell determination of nitric oxide synthase related metabolites in identified nitrergic neurons.
Topics: Animals; Arginine; Argininosuccinic Acid; Cells, Cultured; Citrulline; Electric Conductivity; Electrophoresis, Capillary; Ganglia, Invertebrate; Intracellular Fluid; Lymnaea; Microscopy, Fluorescence; Nitrates; Nitrergic Neurons; Nitric Oxide Synthase; Nitrites; Ornithine | 2005 |
Increased NO production in lysinuric protein intolerance.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acid Transport System y+L; Cells, Cultured; Child; Citrulline; Fibroblasts; Fusion Regulatory Protein 1, Light Chains; Humans; Lysine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites | 2005 |
Effects of acute ammonia toxicity on nitric oxide (NO), citrulline-NO cycle enzymes, arginase and related metabolites in different regions of rat brain.
Topics: Amino Acids; Ammonia; Animals; Arginase; Argininosuccinate Lyase; Argininosuccinate Synthase; Brain; Citrulline; gamma-Aminobutyric Acid; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley | 2005 |
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Arteriosclerosis; Ascorbic Acid; Citrulline; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Diet, Atherogenic; DNA-Binding Proteins; Endothelium, Vascular; ets-Domain Protein Elk-1; Humans; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Proto-Oncogene Proteins; Rabbits; Superoxides; Transcription Factors; Vasodilation; Vitamin E | 2005 |
Vascular and renal effects of dopamine during extracellular volume expansion: Role of nitric oxide pathway.
Topics: Animals; Aorta; Arginine; Blood Pressure; Citrulline; Diuresis; Dopamine; Dopamine Antagonists; Extracellular Fluid; Haloperidol; Kidney; Male; NADPH Dehydrogenase; Natriuresis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Renal Artery; Renal Plasma Flow | 2006 |
Increased nitric oxide (NO) pathway metabolites in the vitreous fluid of patients with rhegmatogenous retinal detachment or diabetic traction retinal detachment.
Topics: Aged; Arginine; Chromatography, High Pressure Liquid; Citrulline; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Retinal Detachment; Signal Transduction; Vitreous Body | 2006 |
Blood cell NO synthesis in response to exercise.
Topics: Adult; Arginase; Arginine; Bicycling; Citrulline; Erythrocytes; Exercise; Humans; Lymphocytes; Male; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Ornithine; Superoxide Dismutase | 2006 |
Infected chronic wounds show different local and systemic arginine conversion compared with acute wounds.
Topics: Acute Disease; Adult; Amino Acids; Arginase; Arginine; Body Fluids; Chronic Disease; Citrulline; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Ornithine; Prospective Studies; Wound Healing; Wound Infection; Wounds and Injuries | 2006 |
Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Arginine; Arnold-Chiari Malformation; Citrulline; Enzyme Inhibitors; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Nitric Oxide Synthase; Nitrites; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2007 |
Measurement of NO and NO synthase.
Topics: Animals; Arginine; Citrulline; Colorimetry; Ethylenediamines; Luminescent Measurements; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Sulfanilamides | 2001 |
Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Citrulline; Dementia, Multi-Infarct; Female; Functional Laterality; Glutamine; Hippocampus; Humans; Isoenzymes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Schizophrenia; Signal Transduction | 2008 |
Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy.
Topics: Adult; Aged; Arginine; Blood Platelets; Carcinoma, Renal Cell; Citrulline; Female; Humans; Interferon-alpha; Kidney Neoplasms; Male; Melanoma; Middle Aged; Monoamine Oxidase; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Skin Neoplasms | 2009 |
Nitric oxide (NO), citrulline-NO cycle enzymes, glutamine synthetase, and oxidative status in kainic acid-mediated excitotoxicity in rat brain.
Topics: Animals; Aspartic Acid; Brain; Citrulline; Endothelium, Vascular; Glutamate-Ammonia Ligase; Kainic Acid; Muscle Relaxation; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2009 |
Level of nitrated proteins in the plasma, platelets and liver of patients with liver cirrhosis.
Topics: Adult; Blood Platelets; Citrulline; Female; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide; Nitrites; Plasma; Proteins | 2009 |
Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.
Topics: Animals; Arginine; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic AMP; Cyclic GMP; Enzyme Activation; Excitatory Amino Acid Agonists; Guanylate Cyclase; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Oncogene Protein v-akt; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2010 |
Surfactant blocks lipopolysaccharide signaling by inhibiting both NFκB and PARP activation in experimental ARDS.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Alveolar Epithelial Cells; Animals; Bronchoalveolar Lavage Fluid; Citrulline; Drug Combinations; Enzyme Activation; Fatty Alcohols; Hydrogen-Ion Concentration; I-kappa B Kinase; Lipopolysaccharides; Lung; Male; NF-kappa B; Nitric Oxide Synthase Type II; Nitrites; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polyethylene Glycols; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Swine | 2011 |
Continuous exposure to L-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells.
Topics: Arginase; Arginine; Ascorbic Acid; Cells, Cultured; Citrulline; Culture Media; Down-Regulation; Drug Tolerance; Free Radical Scavengers; Gene Expression; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Polyethylene Glycols; Superoxide Dismutase; Superoxides | 2012 |
Circulating microparticles carry a functional endothelial nitric oxide synthase that is decreased in patients with endothelial dysfunction.
Topics: Adult; Arginine; Biomarkers; Blotting, Western; Case-Control Studies; Cell-Derived Microparticles; Cells, Cultured; Citrulline; Coronary Stenosis; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Immunoprecipitation; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Reactive Oxygen Species; Time Factors; Vasodilation; Young Adult | 2012 |
Unilateral nephrectomy causes an early abrupt decrease in plasma arginine and simultaneous reduction in glomerular filtration rate in living kidney donors.
Topics: Arginine; Citrulline; Creatinine; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Transplantation; Living Donors; Male; Middle Aged; Nephrectomy; Nitric Oxide; Nitrites; Ornithine; Phenylalanine; Thiobarbituric Acid Reactive Substances; Urea | 2013 |
Circulating blood endothelial nitric oxide synthase contributes to the regulation of systemic blood pressure and nitrite homeostasis.
Topics: Animals; Arginine; Blood Pressure; Carbon Radioisotopes; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Erythrocytes; Homeostasis; Hypertension; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Signal Transduction | 2013 |
Disturbance of redox homeostasis by ornithine and homocitrulline in rat cerebellum: a possible mechanism of cerebellar dysfunction in HHH syndrome.
Topics: Aconitate Hydratase; Animals; Cerebellum; Citrulline; Creatine Kinase; Electron Transport; Glutathione; Homeostasis; Hydrogen Peroxide; Hyperammonemia; Ketoglutarate Dehydrogenase Complex; Nerve Tissue Proteins; Nitrates; Nitrites; Ornithine; Oxidation-Reduction; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances; Urea Cycle Disorders, Inborn | 2013 |
Increased erythrocytes by-products of arginine catabolism are associated with hyperglycemia and could be involved in the pathogenesis of type 2 diabetes mellitus.
Topics: Adult; Aged; Arginine; Blood Glucose; Carbon Isotopes; Case-Control Studies; Citrulline; Diabetes Mellitus, Type 2; Endothelial Cells; Erythrocytes; Female; Glycosylation; Hemoglobins; Hemolysis; Humans; Hyperglycemia; Male; Malondialdehyde; Metabolic Networks and Pathways; Middle Aged; Models, Biological; Nitric Oxide; Nitrites; Ornithine; Oxidative Stress; Urea | 2013 |
α-Tocopherol administration blocks adaptive changes in cell NADH/NAD+ redox state and mitochondrial function leading to inhibition of gastric mucosa cell proliferation in rats.
Topics: Adaptation, Physiological; alpha-Tocopherol; Animals; Antioxidants; bcl-2-Associated X Protein; Cell Proliferation; Citrulline; Drug Evaluation, Preclinical; Gastric Mucosa; Gastritis; Glucose; Male; NAD; Nitrites; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Rats, Wistar | 2013 |
Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis.
Topics: Animals; Aorta; Arginine; Blood Pressure; Cardiovascular System; Citrulline; Dietary Supplements; Homeostasis; Male; Metabolic Networks and Pathways; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Phosphorylation; Rats, Sprague-Dawley | 2015 |
Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia.
Topics: Animals; Arginase; Arginine; Cell Count; Citrulline; Cytokines; Endotoxemia; Integrases; Jejunum; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Organ Specificity; Ornithine; Perfusion; Peroxidase; Receptor, TIE-2; RNA, Messenger | 2014 |
Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Fibronectins; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred DBA; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Tumor Necrosis Factor-alpha | 2014 |
Effects of hyperbaric oxygen on nitric oxide generation in humans.
Topics: Adult; Arginine; Breath Tests; Citrulline; Cyclic GMP; Humans; Hyperbaric Oxygenation; Nitrates; Nitric Oxide; Nitrites; Oxygen; Saliva; Tongue; Young Adult | 2015 |
Plasma kallikrein-bradykinin pathway promotes circulatory nitric oxide metabolite availability during hypoxia.
Topics: Acclimatization; Adult; Altitude; Angiotensinogen; Arginine; Bradykinin; Citrulline; Humans; Hypoxia; Isoprostanes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Oxidative Stress; Plasma Kallikrein; Protein Carbonylation; Proteome; Signal Transduction | 2016 |
Participation of oleic acid in the formation of the aortic aneurysm in Marfan syndrome patients.
Topics: Adult; Aorta; Aortic Aneurysm; Arachidonic Acid; Case-Control Studies; Cholesterol, HDL; Citrulline; Collagen; Female; Gene Expression Regulation; Humans; Male; Marfan Syndrome; Middle Aged; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oleic Acid; Prospective Studies; Signal Transduction; Stearoyl-CoA Desaturase; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2016 |
The Effect Of NO Donor on Calcium Uptake and Reactive Nitrogen Species Production in Mitochondria.
Topics: Animals; Biological Transport; Calcium; Citrulline; Dose-Response Relationship, Drug; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroglycerin; Rats, Wistar; Reactive Nitrogen Species; S-Nitrosothiols | 2016 |
Two weeks of watermelon juice supplementation improves nitric oxide bioavailability but not endurance exercise performance in humans.
Topics: Arginine; Arterial Pressure; Blood Glucose; Citrulline; Citrullus; Dietary Supplements; Fruit and Vegetable Juices; Heart Rate; Humans; Lactic Acid; Male; Malus; Nitric Oxide; Nitrites; Oxygen Consumption; Physical Endurance; Pulmonary Gas Exchange; Young Adult | 2016 |
Experience of correcting endothelial dysfunction in children-residents of radioactively contaminated areas by nitric oxide potential donator citrulline.
Topics: Arginine; Bronchial Spasm; Cardiovascular Diseases; Chernobyl Nuclear Accident; Child; Citrulline; Endothelium, Vascular; Female; Humans; Immunity, Cellular; Immunity, Humoral; Lipid Peroxidation; Malates; Male; Nitric Oxide; Nitric Oxide Donors; Nitrites; Radiation Dosage; Radiation Exposure; Radioactive Pollutants; Rural Population; Survivors; T-Lymphocytes; Ukraine; Urban Population | 2017 |
Exogenous l-ARGININE does not stimulate production OF NO or cGMP within the rat corporal smooth muscle cells in culture.
Topics: Animals; Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Male; Muscle, Smooth; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Penis; Phosphodiesterase 5 Inhibitors; Rats, Sprague-Dawley | 2019 |