nitrendipine has been researched along with verapamil in 236 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 124 (52.54) | 18.7374 |
| 1990's | 76 (32.20) | 18.2507 |
| 2000's | 20 (8.47) | 29.6817 |
| 2010's | 16 (6.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dietel, M; Höllt, V; Kouba, M; Vogt, G | 1 |
| Adams, TC; Carter, JP; Dupont, AC; Farmer, SG; Guzewska, ME; Kachur, JF; Kaiser, C; Noronha-Blob, L; Rzeszotarski, WJ | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Janis, RA; Triggle, DJ | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Cuddon, P; Fleming, A; Floto, RA; Goldsmith, P; Jahreiss, L; O'Kane, CJ; Pask, D; Rubinsztein, DC; Saiki, S; Sarkar, S; Siddiqi, FH; Ttofi, EK; Williams, A | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Sen, S; Sinha, N | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Bills, GF; de Pedro, N; El Aouad, N; Genilloud, O; Goetz, MA; González-Menéndez, V; Martín, J; Ortiz-López, FJ; Pérez-Victoria, I; Platas, G; Reyes, F; Tormo, JR; Vicente, F | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Frattola, A; Mancia, G; Omboni, S; Ravogli, A; Villani, A | 1 |
| Li, QP; Liu, TP | 1 |
| Dhalla, NS; Kolar, F; Lee, SL; Ostadalova, I | 1 |
| Böck, G; Drach, J; Grunicke, H; Hofmann, J; Ludescher, C; Spitaler, M; Wolf, A | 1 |
| Staneva-Stoytcheva, D; Venkova, K | 1 |
| Hallaq, H; Leaf, A; Smith, TW | 1 |
| Campbell, SV; Collauto, F; Pannarale, G; Puddu, PE; Reale, A; Stazi, F | 1 |
| Heym, J; McLean, S; Schmidt, AW | 1 |
| Mason, RP; Moisey, DM; Shajenko, L | 1 |
| Gürdal, H; Sara, Y; Tulunay, FC | 1 |
| Lipsey, LR; Reiss, M; Zhou, ZL | 1 |
| Brunette, MG; Lafond, J; Leclerc, M | 1 |
| Rosenberg, RL; Wang, Y | 1 |
| Birkenhäger, JC; Buurman, CJ; Pols, HA; Schilte, JP; van Leeuwen, JP | 2 |
| Baydoun, AR; Markham, A; Morgan, RM; Sweetman, AJ | 1 |
| Ballesta, JJ; Garcia, AG; Gutierrez, LM; Hidalgo, MJ; Palmero, M; Reig, JA; Viniegra, S | 1 |
| Campbell, P; Cox, T; Peterson, RN | 1 |
| Gambini, F; Gaviraghi, G; Micheli, D; Quartaroli, M; Tarter, G; Trist, DG | 1 |
| Boonen, GJ; de Koster, BM; Elferink, JG | 1 |
| Abbate, R; Boddi, M; Coppo, M; Gensini, GF; Neri Serneri, GG; Prisco, D; Rostagno, C | 1 |
| Hansford, RG; Moreno-Sánchez, R | 1 |
| Glavin, GB; Ogle, CW | 1 |
| Block, LH; Emmons, LR; Erne, P; Matthys, H; Perruchoud, A; Roth, M | 1 |
| Rubin, E; Stewart, G; Thomas, AP | 1 |
| Bia, MJ; Tyler, K | 1 |
| Angus, JA; Coe, SA; Kawabata, H; Knight, KR; O'Brien, BM | 1 |
| de Faria, MG; Leite, CM; Mill, JG; Pires, JG | 1 |
| Colucci, WS; Sperti, G | 1 |
| Murphy, BJ; Tuana, BS | 1 |
| Pinchuk, GV; Pinchuk, LN; Rudenko, AE; Tkachenko, YV | 1 |
| Böhm, M; Erdmann, E; Schwinger, RH | 1 |
| Clementi, F; Pandiella, A; Sher, E | 1 |
| Guarnieri, T; Hano, O; Lakatta, EG; Merillat, JC | 1 |
| Gordon, T; Howlett, SE | 1 |
| Hunter, JB; Pegram, BL; Peters, T; Scheufler, E; Vogelgesang, R; Wermelskirchen, D; Wilffert, B | 1 |
| Peters, T; Scheufler, E | 1 |
| Cattaneo, EA; Cingolani, HE; Rinaldi, GJ | 1 |
| Angeid-Backman, E; Favus, MJ | 1 |
| Hosey, MM; McMahon, KK; Ptasienski, J | 1 |
| Carpenter, CL; Greenberg, DA; Messing, RO | 1 |
| Colucci, WS; Powers, RE | 1 |
| Battaini, F; Govoni, S; Rius, RA; Trabucchi, M | 1 |
| Bryant, SH; Schwartz, A; Walsh, KB | 1 |
| Benavides, J; Bertrand, P; Burgevin, MC; Doble, A; Ferris, O; Gueremy, C; Le Fur, G; Menager, J; Uzan, A; Vaucher, N | 1 |
| Cooper, MS; Schliwa, M | 1 |
| Garcia, ML; Kaczorowski, GJ; King, VF; Reuben, JP; Siegl, PK | 1 |
| Ando, J; Ishii, K; Kano, T | 1 |
| Dalaker, K; Prydz, H | 1 |
| Andresen, MC; Kunze, DL; Torres, LA | 1 |
| Cornwell, MM; Gottesman, MM; Pastan, I | 1 |
| Janis, RA; Sarmiento, JG; Shrikhande, AV; Triggle, DJ | 1 |
| Mir, AK; Spedding, M | 1 |
| Finkel, MS; Tallman, JF | 1 |
| Challoner-Hue, L; Steele, TH | 3 |
| Kjellstedt, A; Ljung, B; Orebäck, B | 1 |
| Carboni, E; Wojcik, WJ | 1 |
| Draznin, B; Kao, M; Sherman, N; Sussman, KE | 1 |
| Cubela, R; Debrevi, L; Jackson, B; Johnston, CI; Whitty, M | 1 |
| Dunn, SM | 2 |
| Marwood, JF | 1 |
| Gandhi, VC; Jones, DJ | 1 |
| Sitges, M | 1 |
| Donowitz, M; Homaidan, FR; Sharp, GW; Weiland, GA | 1 |
| Claessens, MT; Ervasti, JM; Louis, CF; Mickelson, JR | 1 |
| Langer, SZ; Schoemaker, H | 1 |
| Chartrand, C; Dumont, L; Kangha, M; Lord, C | 1 |
| Cox, T; Peterson, RN | 1 |
| Batra, SC; Popper, LD | 1 |
| Belin, C; Carriot, T; Doble, A; Dubroeucq, MC; Guérémy, C; Le Fur, G; Mestre, M; Renault, C; Uzan, A | 1 |
| Ferry, DR; Glossmann, H; Goll, A; Linn, T | 1 |
| Bolli, P; Brouwer, RM; Bühler, FR; Conen, D; Erné, P; Kiowski, W | 1 |
| Dretchen, KL; Henderson, TR; Raines, A | 1 |
| Bühler, FR | 2 |
| Artalejo, CR; Castillo, CF; García, AG; López, MG; Moro, MA | 1 |
| Carvalho, AP; Carvalho, CM; Leysen, JE; Lima, MP; Oliveira, CR | 1 |
| Delahaut, O; Gourdin, A; Swillens, S | 1 |
| Alkadhi, KA; Hogan, YH; Jandhyala, BS; Sabouni, MH | 1 |
| Brush, KL; Hamilton, SL; Hawkes, MJ; Perez, M; Pratt, DR | 1 |
| Müller, A; Noack, E | 1 |
| Haase, H; Vetter, R; Wallukat, G; Will, H | 1 |
| Carmi, R; Rehavi, M; Weizman, A | 1 |
| Doyle, AE | 2 |
| Kannan, MS; Seip, AE | 1 |
| Bauer, JH; Reams, G; Sunderrajan, S | 1 |
| Bolli, P; Bühler, FR; Erne, P; Fadayomi, MO; Hulthén, UL; Kiowski, W; Müller, FB | 1 |
| Lee, HC; Lum, BK | 1 |
| Cruz, LJ; Olivera, BM | 1 |
| Brown, NL; Sirugue, O; Worcel, M | 1 |
| Fishbaugh, J; Freeman, L; Powers, V; Van Sant, R; Yen, A | 1 |
| Horiuchi, K; Horiuchi, KY; Jurman, ME; Ohnishi, ST; Sadanaga, KK | 1 |
| Kessel, D | 1 |
| Dolin, SJ; Little, HJ | 1 |
| Farmer, BB; Green, FJ; Jose, MJ; Watanabe, AM; Wiseman, GL | 1 |
| Dhalla, NS; Elimban, V; Takeo, S | 1 |
| Dudeck, P; Reynolds, IJ; Snyder, SH; Wagner, JA; Weisfeldt, ML; Weisman, HF | 1 |
| Schwartzkroin, PA; Taube, JS | 1 |
| Dillon, JS; Nayler, WG | 1 |
| Fukui, H; Hosomi, N; Takemura, M; Wada, H; Yamamoto, Y | 1 |
| Barbieri, L; Camerini, F; Mestroni, L | 1 |
| Geller, M; Kirch, W; Mönig, H; Ohnhaus, EE; Santos, SR; Stenzel, J | 1 |
| Andrejauskas, E; Hertel, R; Marmé, D | 1 |
| Edmonds, D; Förster, E; Siegenthaler, W; Vetter, W; Wehling, M | 1 |
| Lim, SL; May, PB; Sutter, MC | 1 |
| Karasawa, A; Kubo, K; Nakamizo, N; Oka, T | 1 |
| Geoffroy, M; Mogilnicka, E; Nielsen, M; Rafaelsen, OJ | 1 |
| Altura, BM; Altura, BT; Carella, A; Gebrewold, A; Murakawa, T; Nishio, A | 1 |
| Jumblatt, JE | 1 |
| Glossmann, H; Zernig, G | 1 |
| Endou, K; Sato, T; Yamamoto, H | 1 |
| Mooy, JM; Rahn, KH; van Bortel, LM | 1 |
| Nicita-Mauro, V | 1 |
| Giles, TD; Given, MB; Sander, GE | 1 |
| Bush, LR; D'Alonzo, AJ; Evans, RM; Gaul, SL | 1 |
| Camilión de Hurtado, MC; Gende, OA | 1 |
| Bengtsson, B; Khan, AR; Weiber, R | 1 |
| Joubert, WS; Kociszewska, VJ; Meyer, AC; Meyer, BJ; Nieuwenhuis, JJ | 1 |
| Haraldsson, B; Rippe, B; Zackrisson, U | 1 |
| Giacomini, JC; Giacomini, KM; Nelson, WL; Zobrist, RH | 1 |
| Dolin, SJ; Halsey, MJ; Little, HJ | 1 |
| Chabner, BA; Curt, GA; Fine, RL; Koizumi, S | 1 |
| Fischli, W; Hengartner, U; Holck, M | 1 |
| Bellemann, P | 1 |
| Block, LH; Bolli, P; Bühler, FR; Erne, P; Kiowski, W; Müller, FB | 1 |
| Groth, H; Locher, R; Neyses, L; Stimpel, M; Vetter, W | 1 |
| Kass, RS; Sanguinetti, MC | 1 |
| Fosset, M; Galizzi, JP; Lazdunski, M | 1 |
| Garcia, ML; Kaczorowski, GJ; Reuben, JP; Trumble, MJ | 1 |
| Johnson, CE; Scriabine, A; Steinsland, OS | 1 |
| Pedrinelli, R; Tarazi, RC | 1 |
| Hughes, RJ; Insel, PA; Motulsky, HJ; Snavely, MD | 1 |
| Beatty, DA; Colker, JE; Fairhurst, AS; Thayer, SA | 1 |
| Lee, KS; Tsien, RW | 1 |
| Boles, RG; Roeske, WR; Schoemaker, H; Yamamura, HI | 2 |
| Barry, WH; Lachance, D; Loh, E; Marsh, JD; Smith, TW | 1 |
| Gould, RJ; Murphy, KM; Snyder, SH | 1 |
| Bewtra, A; Cheng, JB; Townley, RG | 1 |
| Gould, RJ; Murphy, KM; Reynolds, IJ; Snyder, SH | 1 |
| Campbell, KP; Denney, GH; Lipshutz, GM | 1 |
| Gengo, PJ; Janis, RA; Luchowski, E; Rampe, DE; Rutledge, A; Triggle, AM; Triggle, DJ | 1 |
| Nayler, WG | 1 |
| Burka, JF; Saad, MH | 1 |
| Pelto, DJ; Rapoport, SI; Suarez-Isla, BA; Thompson, JM | 1 |
| Aguilera, G; Catt, KJ; Finkel, MS; Keiser, HR | 1 |
| Kessel, D; Wilberding, C | 1 |
| Pang, DC; Sperelakis, N | 2 |
| Miller, WC; Moore, JB | 1 |
| Bolger, GT; Gengo, P; Janis, RA; Klockowski, R; Luchowski, E; Siegel, H; Triggle, AM; Triggle, DJ | 1 |
| Quirion, R | 1 |
| Ehlert, FJ; Itoga, E; Roeske, WR; Yamamura, HI | 2 |
| Pert, CB; Quirion, R | 1 |
| Marangos, PJ; Martino, AM; Miller, C; Patel, J | 1 |
| Botta, M; Bruni, G; Budriesi, R; Campiani, G; Chiarini, A; Fiorini, I; Garofalo, A; Nacci, V; Romeo, MR; Tafi, A | 1 |
| Stoeckel, H; Takeda, K | 1 |
| Chapunoff, D; Herman, CA; Romero, MA; Schulmeister, K; Skarda, S; Torres, OA | 1 |
| Mimran, A; Ribstein, J; Sissmann, J | 1 |
| Filloux, FM; Fitts, RC; Skeen, GA; White, HS | 1 |
| García, AG; Guantes, JM; Michelena, P; Montiel, C; Uceda, G | 1 |
| Akimoto, T; Ichida, S; Kishino, H; Matsuda, N; Nakazaki, S; Wada, T | 1 |
| Czirfuzs, A; Fleckenstein-Grün, G; Frey, M; Matyas, S; Thimm, F | 1 |
| Culliford, SJ; Ellory, JC; Mojiminiyi, FB; Stone, PC; Stuart, J | 1 |
| Cingolani, H; Rinaldi, G | 1 |
| Amaro Cendón, A; Calvo Gómez, C; Fernández-López, JA; García-Acuña, JM; Gil de la Peña, M; González-Juanatey, JR | 1 |
| Carvalho, CM; Lopes, MC; Santos, DL | 1 |
| Lasova, LS; Mutafova-Yambolieva, VN; Venkova, KM | 1 |
| Dhalla, NS; Dixon, IM; Hata, T; Kolar, F; Seppet, EK | 1 |
| Lasova, L; Mutafova-Yambolieva, V; Radomirov, R; Staneva-Stoytcheva, D | 1 |
| Greene, LA; Teng, KK | 1 |
| Kiliçcioğlu, B; Nalbantgil, I; Onder, R; Türkoğlu, C | 1 |
| Pencheva, N; Staneva-Stoytcheva, D; Vassilev, PP; Venkova, K | 1 |
| Chen, Y; Fukuo, K; Jiang, B; Kimura, T; Kitano, S; Koh, E; Morimoto, S; Ogihara, T; Sakakibara, S; Yasuda, O | 1 |
| Kojima, I; Mine, T; Sekine, N; Shibata, H; Totsuka, Y; Yasuda, H | 1 |
| Floersheim, GL | 1 |
| Lo, TM; Thayer, SA | 1 |
| Krier, J; Venkova, K | 1 |
| Boland, R; Massheimer, V; Picotto, G | 2 |
| Kikuchi, K; Sugawara, H; Tobise, K | 1 |
| Katoch, SS; Pfitzer, G; Rüegg, JC | 1 |
| García-Segoviano, JA; Naranjo-Rodríguez, EB; Prieto-Gómez, B; Reyes-Vázquez, C; Trujillo-Santana, JT | 1 |
| Berg, HC; Kobel, AM; Pitta, TP; Sherwood, EE | 1 |
| Vassilev, PP | 1 |
| Aşçi, R; Aybek, Z; Büyükalpelli, R; Sarikaya, S; Yildiz, S; Yilmaz, AF | 1 |
| Bril, A; Cheval, B; Faivre, JF; Forest, MC | 1 |
| Garrigos, M; Orlowski, S; Pascaud, C | 1 |
| Antkiewicz-Michaluk, L; Karolewicz, B; Michaluk, J; Vetulani, J | 1 |
| Guan, Z; Saqr, HE; Stokes, BT; Yates, AJ | 1 |
| Lazarova, M; Petkova, B; Staneva-Stoycheva, D | 1 |
| Brochu, M; Picard, S; Simaan, M; St-Louis, J | 1 |
| Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA | 1 |
| Cathala, L; Chesnoy-Marchais, D | 1 |
| Praetorius, HA; Spring, KR | 1 |
| Awe, SO; Harris, LC; Kulkarni, K; LeDay, AM; Ohia, SE; Opere, CA; Sharif, NA | 1 |
| Basile, J | 1 |
| Mitchell, AM; Mortimer, RH; Tom, M | 1 |
| Doyle, KM; Kirby, BP; Murphy, D; Shaw, GG | 1 |
| Dagenais, NJ; Dryden, WF; Hanafy, S; Jamali, F | 1 |
| Cao, Y; He, L; Wang, Q; Zhang, J; Zhang, Y; Zheng, L | 1 |
| Chengliang, Z; Dong, L; Tao, W; Xiping, L; Xiuhua, R; Yanjiao, X | 1 |
| Inaba, K; Kutsuzawa, M; Shiba, K; Takahashi, T; Takayama-Watanabe, E; Watanabe, A | 1 |
| Brightling, CE; Challiss, RA; Gomez, E; Hollins, F; Saunders, R; Sweeney, D | 1 |
8 review(s) available for nitrendipine and verapamil
| Article | Year |
|---|---|
New developments in Ca2+ channel antagonists.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Humans; Ion Channels; Muscle Relaxation; Muscle, Smooth; Potassium; Sodium; Structure-Activity Relationship; Substrate Specificity | 1983 |
Ambulatory blood pressure monitoring.
Topics: Blood Pressure Monitors; Double-Blind Method; Enalapril; Humans; Hypertension; Nitrendipine; Verapamil | 1992 |
Comparison of calcium antagonists with other antihypertensive agents.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Nitrendipine; Verapamil | 1985 |
Effects of calcium entry blockers on renin-angiotensin-aldosterone system, renal function and hemodynamics, salt and water excretion and body fluid composition.
Topics: Animals; Blood Pressure; Body Fluids; Calcium Channel Blockers; Diltiazem; Diuresis; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Nifedipine; Nitrendipine; Renal Circulation; Renin-Angiotensin System; Verapamil; Water-Electrolyte Balance | 1985 |
[Calcium antagonists in congestive heart failure].
Topics: Calcium Channel Blockers; Cardiomyopathy, Dilated; Diltiazem; Felodipine; Heart Failure; Hemodynamics; Humans; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Verapamil | 1988 |
Mg2+-Ca2+ interaction in contractility of vascular smooth muscle: Mg2+ versus organic calcium channel blockers on myogenic tone and agonist-induced responsiveness of blood vessels.
Topics: Animals; Arterioles; Calcium; Calcium Channel Blockers; Magnesium; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Venules; Verapamil | 1987 |
The heterogeneity of the slow channel blockers (calcium antagonists).
Topics: Binding Sites; Calcium Channel Blockers; Cell Membrane; Chemical Phenomena; Chemistry; Humans; Nifedipine; Nitrendipine; Papaverine; Verapamil | 1983 |
The role of existing and newer calcium channel blockers in the treatment of hypertension.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Nitrendipine; Treatment Outcome; Verapamil | 2004 |
10 trial(s) available for nitrendipine and verapamil
| Article | Year |
|---|---|
Effects of slow-release verapamil and nitrendipine on office and 24-hour ambulatory blood pressure in hypertensive patients.
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypertension; Middle Aged; Nitrendipine; Verapamil | 1992 |
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Proline; Renin; Renin-Angiotensin System; Spironolactone; Verapamil | 1985 |
Age, race, blood pressure and renin: predictors for antihypertensive treatment with calcium antagonists.
Topics: Adolescent; Adult; Age Factors; Aged; Black People; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Regression Analysis; Renin; Verapamil | 1985 |
Influence of nitrendipine and verapamil on plasma levels, urinary excretion, and beta-blocking effect of metoprolol.
Topics: Adult; Female; Heart Rate; Humans; Male; Metoprolol; Nitrendipine; Verapamil | 1988 |
[Verapamil and nitrendipine in beta blocker-resistant hypertensive patients].
Topics: Atenolol; Calcium Channel Blockers; Drug Resistance; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Verapamil | 1985 |
Calcium antagonists in the treatment of arterial hypertension in the elderly.
Topics: Age Factors; Aged; Aged, 80 and over; Calcium Channel Blockers; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Verapamil | 1986 |
Calcium antagonists, firstline partners for betablockers in hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension; Nifedipine; Nitrendipine; Renin; Verapamil | 1984 |
Effects of calcium antagonists on adrenaline-induced hypokalaemia.
Topics: Adult; Aged; Blood Glucose; Calcium Channel Blockers; Diltiazem; Epinephrine; Hemodynamics; Humans; Hypokalemia; Middle Aged; Nitrendipine; Potassium; Renin; Verapamil | 1993 |
[Effect of verapamil and nitrendipine on the left ventricular mass and function (systolic and diastolic) in arterial hypertension].
Topics: Double-Blind Method; Echocardiography, Doppler; Follow-Up Studies; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Nitrendipine; Ventricular Function, Left; Verapamil | 1994 |
Combination therapy with verapamil and nitrendipine in patients with hypertension.
Topics: Blood Pressure; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Nitrendipine; Verapamil | 1993 |
218 other study(ies) available for nitrendipine and verapamil
| Article | Year |
|---|---|
Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Biological Transport; Calcium Channel Blockers; Cell Line; Dihydropyridines; Drug Resistance; Haplorhini; Immunoblotting; Membrane Glycoproteins; Mice; RNA, Messenger; Stereoisomerism; Verapamil; Vinblastine | 1992 |
Aminoalkynyldithianes. A new class of calcium channel blockers.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Chemical Phenomena; Chemistry; Guinea Pigs; Heterocyclic Compounds; Muscle, Smooth; Structure-Activity Relationship | 1991 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Topics: Animals; Autophagy; Calcium Channels, L-Type; Clonidine; Cyclic AMP; Humans; Huntington Disease; Imidazoline Receptors; Minoxidil; Protein Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Type C Phospholipases; Verapamil | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Isolation and structural elucidation of cyclic tetrapeptides from Onychocola sclerotica.
Topics: Amino Acids; Ascomycota; Calcium Channels, L-Type; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fermentation; Humans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Vasodilator Agents | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Frequency-dependent depression of Vmax in K(+)-depolarized guinea pig papillary muscle by tetrandrine.
Topics: Action Potentials; Alkaloids; Animals; Benzylisoquinolines; Calcium Channel Blockers; Diltiazem; Electrophysiology; Female; Guinea Pigs; Male; Nitrendipine; Papillary Muscles; Verapamil | 1992 |
Alterations in Ca(2+)-channels during the development of diabetic cardiomyopathy.
Topics: Animals; Blood Glucose; Brain; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cardiomyopathies; Diabetes Mellitus, Experimental; Insulin; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Verapamil | 1992 |
Reversal of multidrug resistance by B859-35, a metabolite of B859-35, niguldipine, verapamil and nitrendipine.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Division; Dihydropyridines; Drug Resistance; Humans; Membrane Glycoproteins; Nitrendipine; Rats; Rhodamines; Verapamil | 1992 |
Effects of the calcium antagonists diltiazem, verapamil and nitrendipine on the contractile responses of guinea-pig isolated ileum to electrical stimulation or carbachol.
Topics: Animals; Carbachol; Diltiazem; Electric Stimulation; Enkephalin, Methionine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nitrendipine; Potassium Chloride; Verapamil | 1992 |
Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cells, Cultured; Dihydropyridines; Fatty Acids, Unsaturated; Fish Oils; Heart; In Vitro Techniques; Ion Channel Gating; Myocardial Contraction; Nitrendipine; Ouabain; Rats; Verapamil | 1992 |
The substance P receptor antagonist CP-96,345 interacts with Ca2+ channels.
Topics: Animals; Binding, Competitive; Biphenyl Compounds; Brain; Calcium Channels; Diltiazem; Drug Interactions; Guinea Pigs; Heart; Nitrendipine; Radioligand Assay; Rats; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Tritium; Verapamil | 1992 |
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil | 1992 |
Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Diltiazem; Formaldehyde; Hindlimb; Inflammation; Male; Nicardipine; Nitrendipine; Pain; Pain Measurement; Rats; Verapamil | 1992 |
Extracellular calcium-dependent regulation of transmembrane calcium fluxes in murine keratinocytes.
Topics: Animals; Calcium; Calcium Channels; Cell Line; Cobalt; Keratinocytes; Lanthanum; Mice; Nickel; Nimodipine; Nitrendipine; Verapamil | 1991 |
Characterization of calcium transport by basal plasma membranes from human placental syncytiotrophoblast.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Biological Transport; Calcium; Carrier Proteins; Cell Membrane; Epithelial Cells; Epithelium; Female; Humans; Magnesium; Maternal-Fetal Exchange; Membrane Proteins; Nitrendipine; Placenta; Pregnancy; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Trophoblasts; Verapamil | 1991 |
Ethaverine, a derivative of papaverine, inhibits cardiac L-type calcium channels.
Topics: Animals; Calcium Channels; Heart; In Vitro Techniques; Lipid Bilayers; Nitrendipine; Papaverine; Parasympatholytics; Phosphodiesterase Inhibitors; Probability; Sarcolemma; Swine; Verapamil | 1991 |
Role of calcium and cAMP in heterologous up-regulation of the 1,25-dihydroxyvitamin D3 receptor in an osteoblast cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenine; Adenylyl Cyclase Inhibitors; Calcitriol; Calcium; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Nitrendipine; Osteoblasts; Parathyroid Hormone; Receptors, Calcitriol; Receptors, Steroid; Up-Regulation; Verapamil | 1990 |
Bay K 8644, modifier of calcium transport and energy metabolism in rat heart mitochondria: a new intracellular site of action.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Diphosphate; Animals; Biological Transport, Active; Calcium; Diltiazem; Energy Metabolism; Female; Glutamates; In Vitro Techniques; Malates; Mitochondria, Heart; NAD; Nitrendipine; Oxidation-Reduction; Oxygen Consumption; Rats; Ruthenium Red; Verapamil | 1990 |
Separate [3H]-nitrendipine binding sites in mitochondria and plasma membranes of bovine adrenal medulla.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium Channels; Cattle; Cell Membrane; Chromaffin System; Diltiazem; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Mitochondria; Nitrendipine; Receptors, Nicotinic; Stereoisomerism; Subcellular Fractions; Verapamil | 1990 |
Ion channels in boar sperm plasma membranes: characterization of a cation selective channel.
Topics: Animals; Cations, Divalent; Cations, Monovalent; Cell Membrane; Epididymis; Ion Channels; Lipid Bilayers; Male; Membrane Fluidity; Nitrendipine; Ruthenium Red; Spermatozoa; Swine; Verapamil | 1991 |
The hemodynamic effects of lacidipine in anesthetized dogs: comparison with nitrendipine, amlodipine, verapamil, and diltiazem.
Topics: Amlodipine; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Stroke Volume; Vascular Resistance; Verapamil | 1991 |
The role of calcium in neutrophil migration: the effect of calcium and calcium-antagonists in electroporated neutrophils.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Caseins; Chemotaxis, Leukocyte; Egtazic Acid; Electric Stimulation; Fluorescent Dyes; In Vitro Techniques; Kinetics; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nifedipine; Nitrendipine; Prenylamine; Rabbits; Verapamil | 1992 |
In vitro effects of two novel calcium antagonists (nitrendipine and nisoldipine) on intraplatelet calcium redistribution, platelet aggregation and thromboxane A2 formation. Comparison with diltiazem, nifedipine and verapamil.
Topics: Adult; Blood Platelets; Calcium; Calcium Channel Blockers; Diltiazem; Female; Humans; In Vitro Techniques; Male; Nifedipine; Nisoldipine; Nitrendipine; Platelet Aggregation; Thromboxane A2; Thromboxane B2; Verapamil | 1991 |
Inhibition of the veratridine-induced increase in cytosolic Ca2+ and respiration by Ca2+ antagonists in isolated cardiac myocytes.
Topics: Amiloride; Animals; Cadmium; Calcium; Calcium Channel Blockers; Cytosol; Female; Hydrogen-Ion Concentration; Isoproterenol; Kinetics; Myocardium; Nitrendipine; Oxygen Consumption; Rats; Rats, Inbred Strains; Sodium; Verapamil; Veratridine | 1991 |
Adrenalectomy, but not vagotomy, reverses the worsening effect of Ca2+ blockers on ethanol-induced gastric lesions in rats.
Topics: Adrenalectomy; Animals; Dexamethasone; Drug Interactions; Ethanol; Gastric Mucosa; Injections, Intraperitoneal; Male; Nitrendipine; Rats; Rats, Inbred Strains; Stomach Ulcer; Vagotomy; Verapamil | 1991 |
Ca(2+)-channel blockers modulate expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and low density lipoprotein receptor genes stimulated by platelet-derived growth factor.
Topics: Amlodipine; Calcium Channel Blockers; Cell Division; Cell Line; Cell Membrane; DNA Replication; Fibroblasts; Gene Expression; Genes; Humans; Hydroxymethylglutaryl CoA Reductases; Kinetics; Nifedipine; Nitrendipine; Platelet-Derived Growth Factor; Receptors, LDL; RNA, Messenger; Skin; Transcription, Genetic; Verapamil | 1991 |
Inhibition by cocaine of excitation-contraction coupling in isolated cardiomyocytes.
Topics: Animals; Calcium; Cell Separation; Cocaine; Dose-Response Relationship, Drug; Electric Conductivity; Heart; Lidocaine; Membrane Potentials; Myocardial Contraction; Myocardium; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum; Sodium Channels; Sympathetic Nervous System; Tetrodotoxin; Verapamil | 1991 |
Evidence that calcium channel blockade prevents cyclosporine-induced exacerbation of renal ischemic injury.
Topics: Animals; Blood Pressure; Calcium Channels; Cyclosporins; Diuresis; Glomerular Filtration Rate; Kidney; Nitrendipine; Rats; Rats, Inbred Strains; Reperfusion Injury; Verapamil | 1991 |
Experience with calcium antagonists nitrendipine, diltiazem, and verapamil and beta 2-agonist salbutamol in salvaging ischemic skin flaps in rabbits.
Topics: Albuterol; Animals; Calcium Channel Blockers; Diltiazem; Injections, Intravenous; Ischemia; Necrosis; Nitrendipine; Rabbits; Reperfusion; Skin; Surgical Flaps; Verapamil | 1991 |
[Comparison of negative chronotropic action of nitrendipine, nifedipine and verapamil on the isolated right atrium of normotensive and renovascular hypertensive rats].
Topics: Animals; Atrial Function, Right; Blood Pressure; Depression, Chemical; Female; Heart Rate; Hypertension, Renovascular; In Vitro Techniques; Isometric Contraction; Male; Nifedipine; Nitrendipine; Rats; Verapamil | 1991 |
Calcium influx modulates DNA synthesis and proliferation in A7r5 vascular smooth muscle cells.
Topics: Animals; Calcium; Calcium Radioisotopes; Cell Division; Cells, Cultured; DNA; Egtazic Acid; Lanthanum; Muscle, Smooth, Vascular; Nitrendipine; Serotonin; Tetradecanoylphorbol Acetate; Thymidine; Tritium; Vasopressins; Verapamil | 1991 |
Calcium ions inhibit the allosteric interaction between the dihydropyridine and phenylalkylamine binding site on the voltage-gated calcium channel in heart sarcolemma but not in skeletal muscle transverse tubules.
Topics: Allosteric Regulation; Aniline Compounds; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Heart; In Vitro Techniques; Isradipine; Kinetics; Muscles; Myocardium; Nitrendipine; Oxadiazoles; Rabbits; Receptors, Nicotinic; Sarcolemma; Verapamil | 1990 |
Calcium channel ligand binding to intact, concanavalin A and cyclic AMP-treated cells of the immune system.
Topics: Animals; Bucladesine; Calcium Channels; Concanavalin A; Isradipine; Leukocytes, Mononuclear; Lymphocyte Activation; Mice; Mice, Inbred CBA; Nitrendipine; Oxadiazoles; Spleen; Verapamil | 1990 |
Different negative inotropic activity of Ca2(+)-antagonists in human myocardial tissue.
Topics: Calcium Channel Blockers; Depression, Chemical; Diltiazem; Heart Atria; Heart Failure; Heart Transplantation; Humans; Isradipine; Myocardial Contraction; Nifedipine; Nitrendipine; Papillary Muscles; Pyridines; Verapamil | 1990 |
Voltage-operated calcium channels in small cell lung carcinoma cell lines: pharmacological, functional, and immunological properties.
Topics: Binding Sites; Binding, Competitive; Calcium Channels; Carcinoma, Small Cell; Conotoxins; Humans; Lung Neoplasms; Nitrendipine; Peptides, Cyclic; Tumor Cells, Cultured; Verapamil | 1990 |
Role of calcium and the calcium channel in the initiation and maintenance of ventricular fibrillation.
Topics: Animals; Biological Transport, Active; Calcium; Calcium Channels; Electric Countershock; In Vitro Techniques; Nitrendipine; Potassium; Rabbits; Sarcoplasmic Reticulum; Ventricular Fibrillation; Verapamil | 1990 |
Functional involvement of calcium in the homologous up-regulation of the 1,25-dihydroxyvitamin D3 receptor in osteoblast-like cells.
Topics: Calcitriol; Calcium; Cell Line; Nitrendipine; Osteoblasts; Receptors, Calcitriol; Receptors, Steroid; Up-Regulation; Verapamil | 1990 |
[3H]-nitrendipine binding in normal and cardiomyopathic hamster hearts: modulation by temperature, verapamil and diltiazem.
Topics: Allosteric Regulation; Animals; Binding Sites; Calcium Channels; Cardiomyopathies; Cricetinae; Dihydropyridines; Diltiazem; In Vitro Techniques; Kinetics; Male; Myocardium; Nitrendipine; Temperature; Verapamil | 1990 |
Uptake of catamphiphilic drugs into erythrocytes and muscular tissue correlates to membrane enrichment and to 45Ca displacement from phosphatidylserine monolayers.
Topics: Binding Sites; Calcium; Cell Membrane; Diltiazem; Erythrocytes; Flunarizine; Humans; In Vitro Techniques; Lidocaine; Muscles; Nitrendipine; Phosphatidylserines; Verapamil | 1990 |
Phosphatidylserine monolayers as models for drug uptake into membranes and tissue.
Topics: Animals; Aorta; Benzothiazoles; Cell Membrane; Diltiazem; Erythrocyte Membrane; Flunarizine; Heart Atria; Humans; Lidocaine; Membranes, Artificial; Models, Biological; Nitrendipine; Pharmaceutical Preparations; Pharmacokinetics; Phosphatidylserines; Piperidines; Rats; Thiazoles; Verapamil | 1990 |
Effect of calcium antagonists on aortae isolated from normotensive and hypertensive rats: relaxation and calcium influx blockade.
Topics: Animals; Aorta; Calcium; Diltiazem; Female; Hypertension; In Vitro Techniques; Male; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Verapamil | 1990 |
Effects of 1,25(OH)2D3 and calcium channel blockers on cecal calcium transport in the rat.
Topics: Animals; Biological Transport, Active; Calcitriol; Calcium; Calcium Channel Blockers; Cecum; Intestinal Absorption; Ion Channels; Male; Nifedipine; Nitrendipine; Rats; Verapamil; Vitamin D Deficiency | 1985 |
High and low affinity states of the dihydropyridine and phenylalkylamine receptors on the cardiac calcium channel and their interconversion by divalent cations.
Topics: Animals; Calcium; Cations, Divalent; Chickens; Dihydropyridines; Heart; Ion Channels; Isradipine; Magnesium; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1985 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil | 1985 |
An increase in putative voltage dependent calcium channel number following reserpine treatment.
Topics: Animals; Catecholamines; Ion Channels; Male; Membrane Potentials; Muscle, Smooth; Nifedipine; Nitrendipine; Prazosin; Rats; Receptors, Adrenergic, alpha; Reserpine; Seminal Vesicles; Verapamil | 1985 |
Age-dependent increase in [3H]verapamil binding to rat cortical membranes.
Topics: Age Factors; Aging; Animals; Binding, Competitive; Calcium; Cerebral Cortex; Ion Channels; Male; Membranes; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Verapamil | 1985 |
Effect of calcium antagonist drugs on calcium currents in mammalian skeletal muscle fibers.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; In Vitro Techniques; Ion Channels; Muscles; Nifedipine; Nitrendipine; Rabbits; Verapamil | 1986 |
Dihydropyridine and peripheral type benzodiazepine binding sites: subcellular distribution and molecular size determination.
Topics: Animals; Benzodiazepinones; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Fractionation; Dogs; Ion Channels; Isoquinolines; Isradipine; Male; Molecular Weight; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Nicotinic; Sarcolemma; Sarcoplasmic Reticulum; Verapamil | 1985 |
Motility of cultured fish epidermal cells in the presence and absence of direct current electric fields.
Topics: Animals; Calcium Channel Blockers; Cell Movement; Cells, Cultured; Cobalt; Electric Stimulation; Epidermal Cells; Epidermis; Fishes; Keratins; Lanthanum; Nifedipine; Nitrendipine; Skin; Skin Physiological Phenomena; Verapamil | 1986 |
Binding of Ca2+ entry blockers to cardiac sarcolemmal membrane vesicles. Characterization of diltiazem-binding sites and their interaction with dihydropyridine and aralkylamine receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Diltiazem; Dithiothreitol; Ethylmaleimide; Female; Guinea Pigs; Hydrogen-Ion Concentration; Iodocyanopindolol; Male; Myocardium; Nifedipine; Nitrendipine; Ouabain; Pindolol; Receptors, Nicotinic; Sodium; Sodium-Potassium-Exchanging ATPase; Stereoisomerism; Temperature; Verapamil | 1986 |
Calcium channel, Ca++ mobilization, and mechanical reactivity of estrogen- and progesterone-treated rat uterus.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Estradiol; Female; In Vitro Techniques; Ion Channels; Kinetics; Nifedipine; Nitrendipine; Potassium; Progesterone; Rats; Receptors, Nicotinic; Uterine Contraction; Uterus; Verapamil | 1986 |
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil | 1986 |
Do calcium antagonists act directly on calcium channels to alter baroreceptor function?
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Ion Channels; Nifedipine; Nimodipine; Nitrendipine; Pressoreceptors; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Carcinoma; Cell Line; Diltiazem; Drug Resistance; Glycoproteins; Humans; Nitrendipine; Quinidine; Verapamil; Vinblastine | 1987 |
[3H]BAY K 8644, a 1,4-dihydropyridine Ca++ channel activator: characteristics of binding to high and low affinity sites in cardiac membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Diltiazem; Edetic Acid; Female; Heart Ventricles; Hot Temperature; Kinetics; Lipolysis; Mathematics; Membranes; Myocardium; Nitrendipine; Propylamines; Rabbits; Tiapamil Hydrochloride; Verapamil | 1987 |
Calcium antagonist properties of diclofurime isomers. II. Molecular aspects: allosteric interactions with dihydropyridine recognition sites.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Chemical Phenomena; Chemistry, Physical; Diltiazem; In Vitro Techniques; Kinetics; Male; Nitrendipine; Oximes; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Stereoisomerism; Temperature; Verapamil | 1987 |
Solubilization of calcium channel antagonist binding sites from rat brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain Chemistry; Calcium Channels; Cholic Acids; Kinetics; Male; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Solubility; Verapamil | 1987 |
Dihydropyridine calcium antagonists and agonists in the isolated perfused Dahl rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Glomerular Filtration Rate; Hypertension, Renal; In Vitro Techniques; Ion Channels; Kidney; Male; Nitrendipine; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Renal Circulation; Sodium Chloride; Verapamil | 1987 |
Vascular versus myocardial selectivity of calcium antagonists studied by concentration-time-effect relations.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Felodipine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nitrendipine; Papillary Muscles; Rats; Rats, Inbred Strains; Time Factors; Verapamil | 1987 |
Dihydropyridine binding sites regulate calcium influx through specific voltage-sensitive calcium channels in cerebellar granule cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Calcium Radioisotopes; Cations, Divalent; Cell Membrane; Cells, Cultured; Cerebellum; Diltiazem; Electrophysiology; Ion Channels; Neurons; Nifedipine; Nitrendipine; Potassium; Rats; Receptors, Nicotinic; Verapamil | 1988 |
Increased vascular response to calcium channel agonist by Dahl S rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Male; Nitrendipine; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Reference Values; Renal Circulation; Sodium, Dietary; Species Specificity; Verapamil | 1988 |
Relationship between cytosolic free calcium concentration and 2-deoxyglucose uptake in adipocytes isolated from 2- and 12-month-old rats.
Topics: Adipose Tissue; Aging; Animals; Calcium; Cytosol; Deoxy Sugars; Deoxyglucose; Glyburide; Insulin; Ion Channels; Kinetics; Male; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Verapamil | 1988 |
Disparate effects of angiotensin converting enzyme inhibitor and calcium blocker treatment on the preservation of renal structure and function following subtotal nephrectomy or streptozotocin-induced diabetes in the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enalapril; Felodipine; Hypertension; Kidney Failure, Chronic; Nephrectomy; Nitrendipine; Proteinuria; Rats; Rats, Inbred Strains; Verapamil | 1987 |
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil | 1988 |
Studies on the site of the interaction between alpha 1-adrenoceptors and 5-HT2 receptors in rat tail arteries.
Topics: Animals; Arteries; Binding Sites; Diltiazem; Felodipine; In Vitro Techniques; Male; Manganese; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Tail; Verapamil | 1988 |
Identification and characterization of [3H]nitrendipine binding sites in rat spinal cord.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Kinetics; Male; Nifedipine; Nitrendipine; Quinacrine; Rats; Rats, Inbred Strains; Spinal Cord; Trifluoperazine; Verapamil | 1988 |
Voltage-dependent calcium channels in skeletal muscle transverse tubules. Measurements of calcium efflux in membrane vesicles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzothiazoles; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Carbocyanines; Cell Membrane; Dihydropyridines; Edetic Acid; Fluorescent Dyes; Isradipine; Lanthanum; Membrane Potentials; Muscles; Nitrendipine; Oxadiazoles; Potassium; Rabbits; Verapamil | 1989 |
Effect of organic and inorganic calcium channel blockers on gamma-amino-n-butyric acid release induced by monensin and veratrine in the absence of external calcium.
Topics: Animals; Calcimycin; Calcium Channel Blockers; gamma-Aminobutyric Acid; Mice; Monensin; Nitrendipine; Osmolar Concentration; Potassium; Ruthenium Red; Verapamil; Veratrine | 1989 |
Two calcium channels in basolateral membranes of rabbit ileal epithelial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chlorides; Diltiazem; Egtazic Acid; Electric Conductivity; Epithelium; Ileum; Male; Nifedipine; Nitrendipine; Rabbits; Sodium; Verapamil | 1989 |
Altered transverse tubule dihydropyridine receptor binding in malignant hyperthermia.
Topics: Adenosine Triphosphatases; Animals; Calcium Channels; Kinetics; Malignant Hyperthermia; Muscles; Nitrendipine; Organelles; Ouabain; Receptors, Nicotinic; Reference Values; Sodium-Potassium-Exchanging ATPase; Swine; Swine Diseases; Verapamil | 1989 |
Effects of Ca++ on [3H]diltiazem binding and its allosteric interaction with dihydropyridine calcium channel binding sites in the rat cortex.
Topics: Allosteric Regulation; Animals; Binding Sites; Calcium; Calcium Channels; Cerebral Cortex; Diltiazem; In Vitro Techniques; Male; Nitrendipine; Rats; Rats, Inbred Strains; Temperature; Verapamil | 1989 |
Evidence of altered dihydropyridine receptor binding capacity following cardiac transplantation.
Topics: Animals; Binding, Competitive; Calcium Channels; Dihydropyridines; Dogs; Graft Rejection; Heart Transplantation; Nifedipine; Nitrendipine; Receptors, Nicotinic; Sarcolemma; Verapamil | 1989 |
Identification of calcium conducting channels in isolated boar sperm plasma membranes.
Topics: Animals; Calcium Channels; Cell Membrane; Electric Conductivity; Liposomes; Male; Membrane Potentials; Nitrendipine; Spermatozoa; Swine; Verapamil | 1989 |
Characterization of membrane calcium channels in nonpregnant and pregnant human uterus.
Topics: Adult; Binding Sites; Calcium Channels; Cell Membrane; Female; Humans; Middle Aged; Myometrium; Nicardipine; Nifedipine; Nitrendipine; Pregnancy; Verapamil | 1989 |
Electrophysiological and pharmacological evidence that peripheral type benzodiazepine receptors are coupled to calcium channels in the heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Female; Guinea Pigs; Heart; Ion Channels; Isoquinolines; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Receptors, GABA-A; Tetraethylammonium Compounds; Verapamil | 1985 |
Molecular approach to the calcium channel.
Topics: Animals; Benzothiazoles; Binding Sites; Brain; Calcium; Cattle; Chemical Phenomena; Chemistry; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles; Thiazoles; Verapamil | 1985 |
Effects of calcium channel blocking agents on neostigmine-induced fasciculations.
Topics: Animals; Calcium Channel Blockers; Electric Stimulation; Facial Muscles; Fasciculation; Male; Neostigmine; Nerve Endings; Nifedipine; Nitrendipine; Phenytoin; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Calcium antagonists as first-choice therapy for low-renin essential hypertension.
Topics: Antihypertensive Agents; Biomarkers; Calcium Channel Blockers; Cardiovascular System; Humans; Hypertension; Kidney; Male; Middle Aged; Models, Biological; Nitrendipine; Renin; Verapamil | 1989 |
Variable, voltage-dependent, blocking effects of nitrendipine, verapamil, diltiazem, cinnarizine and cadmium on adrenomedullary secretion.
Topics: Adrenal Medulla; Animals; Cadmium; Calcium Channel Blockers; Catecholamines; Cats; Cinnarizine; Diltiazem; Electric Stimulation; In Vitro Techniques; Nitrendipine; Verapamil | 1989 |
Partition of Ca2+ antagonists in brain plasma membranes.
Topics: Animals; Brain; Calcium Channel Blockers; Flunarizine; Kinetics; Liposomes; Nitrendipine; Sheep; Synaptic Membranes; Verapamil | 1989 |
Characterization of the interaction constants for the binding of two unlabelled ligands to the sites of a receptor. An experimental strategy.
Topics: Ligands; Models, Biological; Nitrendipine; Receptors, Drug; Software; Verapamil | 1989 |
Effects of felodipine and verapamil on transmission in the isolated superior cervical ganglion of the rat.
Topics: Action Potentials; Animals; Autonomic Nervous System; Calcium Channel Blockers; Felodipine; Ganglia, Spinal; Hexamethonium Compounds; In Vitro Techniques; Nitrendipine; Rats; Synaptic Transmission; Verapamil | 1987 |
Low affinity binding sites for 1,4-dihydropyridines in mitochondria and in guinea pig ventricular membranes.
Topics: Animals; Calcium Channels; Cations, Divalent; Cell Membrane; Diltiazem; Guinea Pigs; Heart Ventricles; Hot Temperature; Mitochondria; Myocardium; Nimodipine; Nitrendipine; Osmolar Concentration; Protein Denaturation; Receptors, Nicotinic; Sodium Chloride; Verapamil | 1987 |
Additive competitive interaction of verapamil and quinidine at alpha-adrenergic receptors of isolated cardiac guinea pig myocytes and human platelets.
Topics: Animals; Binding, Competitive; Blood Platelets; Cell Membrane; Cells, Cultured; Drug Interactions; Guinea Pigs; Humans; Isomerism; Kinetics; Myocardium; Nitrendipine; Quinidine; Receptors, Adrenergic, alpha; Verapamil | 1988 |
Characterization of calcium antagonist receptors in highly purified porcine cardiac sarcolemma.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Heart Rate; In Vitro Techniques; Kinetics; Myocardium; Nitrendipine; Receptors, Nicotinic; Sarcolemma; Swine; Verapamil | 1987 |
Tricyclic antidepressants and calcium channel blockers: interactions at the (-)-desmethoxyverapamil binding site and the serotonin transporter.
Topics: Animals; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Calcium Channels; Imipramine; In Vitro Techniques; Kinetics; Male; Nitrendipine; Rats; Receptors, Nicotinic; Receptors, Serotonin; Serotonin; Verapamil | 1988 |
Comparison of calcium antagonists with other antihypertensive agents.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Nitrendipine; Verapamil | 1986 |
Mechanisms of alpha-adrenoceptor mediated contractions of rat mesenteric artery.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; In Vitro Techniques; Kinetics; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction; Verapamil | 1986 |
Protective action of calcium entry blockers in endotoxin shock.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Escherichia coli; Heart Rate; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Shock, Septic; Verapamil | 1986 |
Calcium channel antagonists. Omega-conotoxin defines a new high affinity site.
Topics: Animals; Binding, Competitive; Brain; Calcium Channel Blockers; Chick Embryo; Cinnarizine; Diltiazem; Flunarizine; Muscles; Nifedipine; Nitrendipine; Prenylamine; Rana pipiens; Synaptosomes; Time Factors; Verapamil | 1986 |
The effects of some slow channel blocking drugs on high affinity serotonin uptake by rat brain synaptosomes.
Topics: Animals; Bepridil; Brain; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Pyrrolidines; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes; Temperature; Time Factors; Verapamil | 1986 |
Cell cycle dependence of calmodulin levels during HL-60 proliferation and myeloid differentiation. No changes during pre-commitment.
Topics: Calmodulin; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Humans; Leukemia, Myeloid, Acute; Nifedipine; Nitrendipine; Trifluoperazine; Verapamil | 1986 |
Nitrendipine, nifedipine and verapamil inhibit the in vitro formation of irreversibly sickled cells.
Topics: Adult; Anemia, Sickle Cell; Calcium; Calcium Channel Blockers; Calmodulin; Dehydration; Erythrocytes, Abnormal; Humans; In Vitro Techniques; Lanthanum; Nifedipine; Nitrendipine; Phosphodiesterase Inhibitors; Potassium; Verapamil; Zinc | 1986 |
Interactions among membrane transport systems: anthracyclines, calcium antagonists and anti-estrogens.
Topics: Animals; Antibiotics, Antineoplastic; Biological Transport; Calcium Channel Blockers; Daunorubicin; Doxorubicin; Drug Resistance; Estrogen Antagonists; Kinetics; Leukemia P388; Mice; Naphthacenes; Nifedipine; Nitrendipine; Tamoxifen; Verapamil | 1986 |
Augmentation by calcium channel antagonists of general anaesthetic potency in mice.
Topics: Anesthesia, General; Animals; Argon; Calcium Channel Blockers; Cinnarizine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flunarizine; Male; Mice; Nifedipine; Nitrendipine; Pentobarbital; Time Factors; Verapamil | 1986 |
Effect of membrane depolarization on binding of [3H]nitrendipine to rat cardiac myocytes.
Topics: Aconitine; Animals; Binding Sites; Binding, Competitive; Calcium Channels; Cell Survival; Diltiazem; Heart; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Myocardium; Nifedipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Verapamil | 1985 |
Modification of cardiac sarcolemmal Na+-Ca2+ exchange by diltiazem and verapamil.
Topics: Acebutolol; Animals; Benzazepines; Ca(2+) Mg(2+)-ATPase; Calcium; Diltiazem; In Vitro Techniques; Myocardium; Nifedipine; Nitrendipine; Propranolol; Rats; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1985 |
Calcium antagonist receptors in cardiomyopathic hamster: selective increases in heart, muscle, brain.
Topics: Animals; Brain; Brain Chemistry; Calcium; Calcium Channels; Cardiomyopathy, Hypertrophic; Cricetinae; Disease Models, Animal; Female; Heart; Male; Mesocricetus; Muscle, Smooth; Muscles; Myocardium; Nifedipine; Nitrendipine; Receptors, Nicotinic; Synaptosomes; Verapamil | 1986 |
Ineffectiveness of organic calcium channel blockers in antagonizing long-term potentiation.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Cinnarizine; Diazepam; Flunarizine; Guinea Pigs; Hippocampus; Neurons; Nifedipine; Nitrendipine; Reaction Time; Synaptic Transmission; Verapamil | 1986 |
[3H]-verapamil binding to rat cardiac sarcolemmal membrane fragments; an effect of ischaemia.
Topics: Animals; Calcium Channels; Coronary Circulation; In Vitro Techniques; Male; Myocardium; Nitrendipine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Sarcolemma; Verapamil | 1987 |
Solubilization and characterization of the nitrendipine receptor in rat brain.
Topics: Animals; Brain Chemistry; Calcium Channels; Centrifugation, Density Gradient; Chromatography, Gel; Detergents; Molecular Weight; Nitrendipine; Prenylamine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Solubility; Verapamil | 1987 |
Specific binding of the calcium antagonist [3H]verapamil to membrane fractions from plants.
Topics: Binding Sites; Diltiazem; Hydrogen-Ion Concentration; Kinetics; Membranes; Nifedipine; Nitrendipine; Plants; Verapamil | 1985 |
Manganese can inhibit or potentiate contractile responses in mesenteric portal vein.
Topics: Animals; Barium; Calcium; Felodipine; Gallopamil; In Vitro Techniques; Male; Manganese; Mesenteric Veins; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Spectrophotometry, Atomic; Strontium; Tissue Distribution; Verapamil | 1988 |
Antihypertensive effects of intravenous administration of benidipine hydrochloride and some other calcium antagonists in conscious, spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intravenous; Male; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Verapamil | 1988 |
Effect of nifedipine on the shuttlebox escape deficit induced by inescapable shock in the rat.
Topics: Animals; Binding Sites; Brain; Depression; Electroshock; Escape Reaction; Imipramine; Kinetics; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Verapamil | 1988 |
Effects of calcium channel antagonists on the depolarization-evoked release of norepinephrine in the rabbit iris-ciliary body.
Topics: Action Potentials; Adrenergic Fibers; Animals; Calcium Channel Blockers; Ciliary Body; Cobalt; In Vitro Techniques; Iris; Nitrendipine; Norepinephrine; Potassium; Rabbits; Verapamil | 1988 |
A novel 1,4-dihydropyridine-binding site on mitochondrial membranes from guinea-pig heart, liver and kidney.
Topics: Animals; Binding Sites; Centrifugation, Density Gradient; Dihydropyridines; Diltiazem; Guinea Pigs; Intracellular Membranes; Kidney; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Nitrendipine; Osmolar Concentration; Subcellular Fractions; Verapamil | 1988 |
Comparison of the effects of calcium channel blockers and antiarrhythmic drugs on digitalis-induced oscillatory afterpotentials on canine Purkinje fiber.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Digitalis; Diltiazem; Dogs; Electric Stimulation; Female; Heart Conduction System; Male; Mexiletine; Nicardipine; Nifedipine; Nitrendipine; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Purkinje Fibers; Verapamil | 1987 |
The use of calcium antagonists in patients with renal failure.
Topics: Calcium Channel Blockers; Diltiazem; Humans; Kidney Failure, Chronic; Nifedipine; Nitrendipine; Verapamil | 1987 |
Evidence for Des-Tyr1-D-Ala2-leucine5-enkephalinamide calcium agonist activity in vascular smooth muscle.
Topics: Animals; Calcium; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Potassium Chloride; Rats; Reserpine; Serotonin; Verapamil | 1987 |
Response of isolated Dahl rat kidney to calcium antagonists.
Topics: Animals; Calcium; Drug Resistance; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Male; Nitrendipine; Perfusion; Rats; Sodium; Sodium Chloride; Verapamil | 1987 |
Comparative effects of verapamil, diltiazem and felodipine during experimental digitalis-induced arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Dogs; Felodipine; Female; Male; Nitrendipine; Ouabain; Verapamil | 1987 |
[Increase of the depressive effect of verapamil in acidosis].
Topics: Acidosis; Animals; Depression, Chemical; Heart Atria; Hydrogen-Ion Concentration; Myocardial Contraction; Nifedipine; Nitrendipine; Rats; Sinoatrial Node; Verapamil | 1986 |
Low potency of Ca antagonists in smooth muscle from different levels of the respiratory tract.
Topics: Animals; Bronchi; Calcium Channel Blockers; Felodipine; Female; Gallopamil; Guinea Pigs; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Respiratory Muscles; Trachea; Verapamil | 1987 |
Dihydropyridine calcium antagonists depress the amplitude of the plasma melatonin cycle in baboons.
Topics: Animals; Calcium Channel Blockers; Male; Melatonin; Nifedipine; Nisoldipine; Nitrendipine; Papio; Verapamil | 1986 |
Calcium dependence of histamine-induced increases in capillary permeability in isolated perfused rat hindquarters.
Topics: Animals; Calcium; Capillary Permeability; Capillary Resistance; Felodipine; Hindlimb; Histamine; Magnesium; Male; Nitrendipine; Perfusion; Rats; Rats, Inbred Strains; Verapamil | 1986 |
The interaction of phenylalkylamine calcium channel blockers with the 1,4-dihydropyridine binding site.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Dihydropyridines; Heart; Kinetics; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Drug; Structure-Activity Relationship; Verapamil | 1986 |
Calcium channel antagonists decrease the ethanol withdrawal syndrome.
Topics: Animals; Calcium Channel Blockers; Diazepam; Ethanol; Flunarizine; Male; Motor Activity; Nimodipine; Nitrendipine; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Verapamil | 1986 |
Effect of calcium channel blockers on human CFU-GM with cytotoxic drugs.
Topics: Adolescent; Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Cells; Calcium Channel Blockers; Cells, Cultured; Colony-Forming Units Assay; Cricetinae; Doxorubicin; Drug Interactions; Drug Resistance; Granulocytes; Humans; Monocytes; Neoplasms; Nitrendipine; Verapamil; Vinblastine; Vincristine | 1987 |
Effects of temperature and allosteric modulators on [3H] nitrendipine binding: methods for detecting potential Ca2+ channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Animals; Benzothiazoles; Binding Sites; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Microsomes; Myocardium; Nifedipine; Nitrendipine; Propylamines; Temperature; Thiazoles; Tiapamil Hydrochloride; Verapamil | 1984 |
Interaction of the calcium channel activating 3H-BAY K 8644 and inhibiting 3H-verapamil with specific receptor sites on cultured beating myocardial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Calcium Channel Blockers; Cells, Cultured; Kinetics; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Receptors, Drug; Verapamil | 1984 |
Antihypertensive therapy with the long-acting calcium antagonist nitrendipine.
Topics: Adult; Aged; Blood Pressure; Body Weight; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Renin; Verapamil | 1984 |
Human red blood cells--an ideal model system for the action of calcium agonists and antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Erythrocytes; Humans; Ion Channels; Nicardipine; Nifedipine; Nitrendipine; Pyridines; Stimulation, Chemical; Verapamil | 1984 |
Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.
Topics: Animals; Binding Sites; Cattle; Dihydropyridines; Electrophysiology; Heart Conduction System; Ion Channels; Membrane Potentials; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Pyridines; Verapamil | 1984 |
Properties of receptors for the Ca2+-channel blocker verapamil in transverse-tubule membranes of skeletal muscle. Stereospecificity, effect of Ca2+ and other inorganic cations, evidence for two categories of sites and effect of nucleoside triphosphates.
Topics: Animals; Bepridil; Binding, Competitive; Calcium; Calcium Channels; Cations, Divalent; Cations, Monovalent; Diltiazem; Electrochemistry; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Muscles; Nifedipine; Nitrendipine; Nucleotides; Pyrrolidines; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil | 1984 |
Characterization of verapamil binding sites in cardiac membrane vesicles.
Topics: Animals; Calcium Channels; Diltiazem; Heart Ventricles; Kinetics; Myocardium; Nifedipine; Nitrendipine; Receptors, Nicotinic; Sarcolemma; Swine; Verapamil | 1984 |
Dopamine antagonist effect of verapamil on isolated perfused rabbit ear artery.
Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Nifedipine; Nitrendipine; Perfusion; Rabbits; Sulpiride; Vasoconstriction; Verapamil | 1983 |
Interference of calcium entry blockade in vivo with pressor responses to alpha-adrenergic stimulation: effects of two unrelated blockers on responses to both exogenous and endogenously released norepinephrine.
Topics: Adrenergic alpha-Agonists; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electric Stimulation; Female; Nifedipine; Nitrendipine; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Vasoconstriction; Verapamil; Yohimbine | 1984 |
Interaction of verapamil and other calcium channel blockers with alpha 1- and alpha 2-adrenergic receptors.
Topics: Animals; Binding, Competitive; Blood Platelets; Calcium Channel Blockers; Drug Interactions; Humans; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Verapamil | 1983 |
A calcium antagonist drug binding site in skeletal muscle sarcoplasmic reticulum: evidence for a calcium channel.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Cinnarizine; Egtazic Acid; Flunarizine; Gallic Acid; Ion Channels; Muscle Contraction; Neuromuscular Junction; Nifedipine; Nitrendipine; Pyridines; Rabbits; Sarcoplasmic Reticulum; Verapamil | 1983 |
Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells.
Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Cats; Diltiazem; Gallopamil; Heart; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Nifedipine; Nitrendipine; Verapamil | 1983 |
Allosteric modulation by diltiazem and verapamil of [3H]nitrendipine binding to calcium channel sites in rat brain.
Topics: Allosteric Site; Animals; Benzazepines; Brain; Calcium; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Ion Channels; Kinetics; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Synaptosomes; Verapamil | 1983 |
Relationship of binding of a calcium channel blocker to inhibition of contraction in intact cultured embryonic chick ventricular cells.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Chick Embryo; Diltiazem; Heart; In Vitro Techniques; Ion Channels; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Tritium; Verapamil | 1983 |
A simple sensitive radioreceptor assay for calcium antagonist drugs.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cattle; Cell Membrane; Cerebral Cortex; Diltiazem; In Vitro Techniques; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Prenylamine; Radioligand Assay; Receptors, Nicotinic; Verapamil | 1983 |
Identification of calcium antagonist receptor binding sites using (3H)nitrendipine in bovine tracheal smooth muscle membranes.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cattle; Cromolyn Sodium; Kinetics; Muscle, Smooth; Nifedipine; Nisoldipine; Nitrendipine; Receptors, Nicotinic; Trachea; Verapamil | 1984 |
Calcium channel blockade: possible explanation for thioridazine's peripheral side effects.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Ejaculation; Female; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; Propylamines; Rats; Rats, Inbred Strains; Sexual Dysfunction, Physiological; Thioridazine; Tiapamil Hydrochloride; Vas Deferens; Verapamil | 1984 |
Direct photoaffinity labeling of the high affinity nitrendipine-binding site in subcellular membrane fractions isolated from canine myocardium.
Topics: Affinity Labels; Animals; Calcium Channel Blockers; Calcium Channels; Dogs; Intracellular Membranes; Light; Myocardium; Nifedipine; Nitrendipine; Phenylmethylsulfonyl Fluoride; Receptors, Nicotinic; Sarcolemma; Sarcoplasmic Reticulum; Sulfones; Ultraviolet Rays; Verapamil | 1984 |
Chemical and pharmacological approaches to the definition and quantitation of calcium channels.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dogs; Guinea Pigs; Ion Channels; Microsomes; Muscle, Smooth; Muscles; Myocardium; Neurons; Nifedipine; Nitrendipine; Receptors, Nicotinic; Verapamil | 1983 |
Role of calcium in arachidonic acid-induced contractions of guinea pig airways.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channel Blockers; Edetic Acid; Gallic Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Lanthanum; Lung; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; SRS-A; Trachea; Verapamil | 1984 |
Blockers of calcium permeability inhibit neurite extension and formation of neuromuscular synapses in cell culture.
Topics: Age Factors; Animals; Cadmium; Calcium Channel Blockers; Chick Embryo; Cobalt; Gallopamil; Lanthanum; Manganese; Neuromuscular Junction; Nifedipine; Nitrendipine; Retina; Verapamil | 1984 |
[3H]nitrendipine binding to adrenal capsular membranes.
Topics: Adrenal Medulla; Aldosterone; Animals; Binding Sites; Binding, Competitive; Diltiazem; Kinetics; Membranes; Nifedipine; Nitrendipine; Rats; Verapamil | 1984 |
Mode of action of calcium antagonists which alter anthracycline resistance.
Topics: Animals; Antibiotics, Antineoplastic; Biological Transport; Calcium Channel Blockers; Cell Line; Daunorubicin; Doxorubicin; Drug Resistance; Leukemia P388; Mice; Naphthacenes; Nifedipine; Nitrendipine; Verapamil | 1984 |
Uptake of calcium antagonistic drugs into muscles as related to their lipid solubilities.
Topics: Animals; Bepridil; Calcium Channel Blockers; Lipid Metabolism; Muscles; Nifedipine; Nitrendipine; Pyrrolidines; Rana pipiens; Rats; Sarcoplasmic Reticulum; Solubility; Verapamil | 1984 |
Temperature-dependent modulation of [3H]nitrendipine binding by the calcium channel antagonists verapamil and diltiazem in rat brain synaptosomes.
Topics: Animals; Benzazepines; Binding Sites; Brain; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Synaptosomes; Temperature; Tritium; Verapamil | 1984 |
High affinity binding sites for [3H]-nitrendipine in rabbit uterine smooth muscle.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cell Membrane; Cinnarizine; Depression, Chemical; Dose-Response Relationship, Drug; Female; Flunarizine; Muscle, Smooth; Nifedipine; Nitrendipine; Rabbits; Uterus; Verapamil | 1984 |
Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cinnarizine; Cobalt; Dose-Response Relationship, Drug; Drug Synergism; Flunarizine; Guinea Pigs; Ileum; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines; Structure-Activity Relationship; Verapamil | 1983 |
Uptake of [3H]nitrendipine into cardiac and smooth muscles.
Topics: Animals; Cats; Chick Embryo; Ileum; Kinetics; Muscle, Smooth; Myocardium; Nifedipine; Nitrendipine; Pyridines; Verapamil | 1983 |
Autoradiographic localization of a calcium channel antagonist, [3H]nitrendipine, binding site in rat brain.
Topics: Animals; Autoradiography; Binding Sites; Brain; Calcium Channel Blockers; Hippocampus; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Verapamil | 1983 |
The interaction of [3H]nitrendipine with receptors for calcium antagonists in the cerebral cortex and heart of rats.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Chloride; Cerebral Cortex; Diltiazem; Gallopamil; Kinetics; Lanthanum; Male; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Drug; Verapamil | 1982 |
The binding of [3H]nitrendipine to receptors for calcium channel antagonists in the heart, cerebral cortex, and ileum of rats.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cerebral Cortex; Heart; Ileum; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Verapamil | 1982 |
Certain calcium antagonists are potent displacers of [3H]phencyclidine (PCP) binding in rat brain.
Topics: Animals; Binding, Competitive; Brain; Calcium Channel Blockers; Gallopamil; In Vitro Techniques; Nifedipine; Nitrendipine; Olfactory Bulb; Phencyclidine; Rats; Verapamil | 1982 |
Specific calcium antagonist binding sites in brain.
Topics: Animals; Binding Sites; Brain; Calcium; Cell Membrane; Hot Temperature; Male; Membrane Proteins; Nerve Tissue Proteins; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Trypsin; Verapamil | 1982 |
Pyrrolo[2,1-c][1,4]benzothiazines: synthesis, structure-activity relationships, molecular modeling studies, and cardiovascular activity.
Topics: Animals; Binding, Competitive; Brain; Calcium Channel Blockers; Computer Graphics; Diltiazem; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Models, Molecular; Myocardial Contraction; Nitrendipine; Pyrroles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazines; Verapamil | 1995 |
Calcium-sensitivity of the plasmalemmal delayed rectifier potassium current suggests that calcium influx in pulvinar protoplasts from Mimosa pudica L. can be revealed by hyperpolarization.
Topics: Bepridil; Calcium; Calcium Channel Blockers; Cells, Cultured; Electric Conductivity; Ionomycin; Ionophores; Nitrendipine; Plant Physiological Phenomena; Potassium Channels; Protoplasts; Pulvinus; Verapamil | 1995 |
Leukotriene C4-stimulated contractions in bullfrog lung are affected by cold acclimation and calcium antagonists.
Topics: Acclimatization; Animals; Caffeine; Calcium Channel Blockers; Calcium-Transporting ATPases; Cold Temperature; Contracture; Egtazic Acid; Eicosapentaenoic Acid; Female; Hot Temperature; Leukotriene C4; Lung; Male; Nicardipine; Nifedipine; Nitrendipine; Rana catesbeiana; SRS-A; Terpenes; Thapsigargin; Verapamil | 1995 |
The dihydropyridine nitrendipine inhibits [3H]MK 801 binding to mouse brain sections.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Autoradiography; Binding, Competitive; Brain; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Nifedipine; Nimodipine; Nitrendipine; Software; Verapamil | 1994 |
Effects of Ca2+ channel antagonist subtypes on mitochondrial Ca2+ transport.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Cattle; Diltiazem; Flunarizine; In Vitro Techniques; Mitochondria; Nitrendipine; Verapamil | 1995 |
Specific bindings of [3H](+)PN200-110 and [125I]omega-conotoxin to crude membranes from differentiated NG108-15 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Bucladesine; Cell Differentiation; Cell Membrane; Diltiazem; Glioma; Hybrid Cells; Isradipine; Mollusk Venoms; Neuroblastoma; Nitrendipine; omega-Conotoxin GVIA; Potassium Chloride; Rats; Tumor Cells, Cultured; Verapamil | 1993 |
Experimental vasoprotection by calcium antagonists against calcium-mediated arteriosclerotic alterations.
Topics: Adult; Aged; Aged, 80 and over; Animals; Arteriosclerosis; Calcium; Calcium Channel Blockers; Cells, Cultured; Cholecalciferol; Cholesterol; Coronary Vessels; Diltiazem; Disease Models, Animal; Humans; Hypertension; Middle Aged; Muscle, Smooth, Vascular; Nicotine; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Risk Factors; Verapamil | 1994 |
Additive in vitro effects of anti-sickling drugs.
Topics: Anemia, Sickle Cell; Antisickling Agents; Benzaldehydes; Calcium; Cells, Cultured; Clotrimazole; Drug Synergism; Erythrocyte Deformability; Erythrocyte Indices; Erythrocytes; Hemorheology; Humans; Nitrendipine; Oxidation-Reduction; Potassium; Potassium Channels; Verapamil | 1994 |
Relationship between baseline blood pressure and blood pressure decrease after calcium channel blockers in conscious rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Consciousness; Hypertension; Male; Nisoldipine; Nitrendipine; Nitroprusside; Rats; Rats, Wistar; Verapamil | 1994 |
Calcium channel blockers inhibit the (Ca2+ + Mg2+)-ATPase activity and the 125I-calmodulin binding in brain membranes.
Topics: Animals; Autoradiography; Binding Sites; Brain; Ca(2+) Mg(2+)-ATPase; Calcium Channel Blockers; Calmodulin; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Flunarizine; Iodine Radioisotopes; Nitrendipine; Sheep; Stereoisomerism; Synaptic Membranes; Trifluoperazine; Verapamil | 1994 |
Atrial natriuretic peptide inhibits the purinergic and not the adrenergic component of electrically induced contractile responses in guinea pig vas deferens.
Topics: Adenosine Triphosphate; Adrenergic Antagonists; Animals; Atrial Natriuretic Factor; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Naloxone; Neurotransmitter Agents; Nitrendipine; Phenylephrine; Prazosin; Receptors, Adrenergic; Receptors, Purinergic; Vas Deferens; Verapamil; Yohimbine | 1993 |
Regulation of cardiac sarcolemmal Ca2+ channels and Ca2+ transporters by thyroid hormone.
Topics: Animals; Calcium Channels; Calcium-Binding Proteins; Heart; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Male; Myocardial Contraction; Nitrendipine; Perfusion; Rats; Rats, Sprague-Dawley; Sarcolemma; Thyroid Hormones; Verapamil | 1993 |
Effects of subchronic exposure of rats to lead or zinc on alpha-adrenoceptor-mediated contractile responses in isolated vas deferens.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Lead; Male; Muscle Contraction; Muscle, Smooth; Nitrendipine; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Sulfates; Vas Deferens; Verapamil; Yohimbine; Zinc Compounds; Zinc Sulfate | 1993 |
Depolarization maintains neurites and priming of PC12 cells after nerve growth factor withdrawal.
Topics: Animals; Cytoskeletal Proteins; Kinetics; Microscopy, Electron; Nerve Growth Factors; Neurites; Nitrendipine; PC12 Cells; Phosphoproteins; Phosphorylation; Potassium; Time Factors; Verapamil | 1993 |
Changes in the contractile responses to carbachol and in the inhibitory effects of verapamil and nitrendipine on isolated smooth muscle preparations from rats subchronically exposed to Co2+ and Ni2+.
Topics: Animals; Carbachol; Cobalt; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nickel; Nitrendipine; Rats; Rats, Wistar; Trachea; Verapamil | 1993 |
Calciseptine binding to a 1,4-dihydropyridine recognition site of the L-type calcium channel of rat synaptosomal membranes.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Cell Fractionation; Dihydropyridines; Diltiazem; Elapid Venoms; Intracellular Membranes; Kinetics; Ligands; Male; Nitrendipine; omega-Conotoxins; Peptides; Rats; Rats, Wistar; Synaptosomes; Verapamil | 1993 |
Activin A increases intracellular free calcium concentrations in rat pancreatic islets.
Topics: Activins; Animals; Calcium; Carbachol; Cyclic AMP; Diazoxide; Inhibins; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nifedipine; Nitrendipine; Rats; Rats, Wistar; Verapamil | 1993 |
Radioprotective effects of calcium antagonists used alone or with other types of radioprotectors.
Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Diltiazem; Dimethyl Sulfoxide; Drug Combinations; Female; Flunarizine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Verapamil; Zinc | 1993 |
Refilling the inositol 1,4,5-trisphosphate-sensitive Ca2+ store in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Animals; Bradykinin; Calcium; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Flunarizine; Glioma; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Mice; Neuroblastoma; Nitrendipine; Terpenes; Thapsigargin; Tumor Cells, Cultured; Verapamil | 1993 |
Postjunctional alpha 1- and beta-adrenoceptor effects of noradrenaline on electrical slow waves and phasic contractions of cat colon circular muscle.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium Channel Blockers; Cats; Colon; Electrophysiology; Female; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Nitrendipine; Norepinephrine; Peristalsis; Phenylephrine; Ryanodine; Verapamil | 1995 |
Acute stimulation of intestinal cell calcium influx induced by 17 beta-estradiol via the cAMP messenger system.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Calcium; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Duodenum; Enzyme Inhibitors; Estradiol; Female; Nitrendipine; Rats; Rats, Wistar; Second Messenger Systems; Thionucleotides; Verapamil | 1996 |
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Felodipine; Fumarates; Heart; Iron; Lipid Peroxidation; Male; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Verapamil | 1996 |
Differential effects of a K+ channel agonist and Ca2+ antagonists on myosin light chain phosphorylation in relaxation of endothelin-1-contracted tracheal smooth muscle.
Topics: Animals; Benzopyrans; Dihydropyridines; Endothelin-1; Muscle Relaxation; Muscle, Smooth; Myosin Light Chains; Nitrendipine; Sheep; Trachea; Verapamil | 1997 |
Apamin blocks the direct relaxant effect of melatonin on rat ileal smooth muscle.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Apamin; Calcium; Calcium Channel Blockers; Carbachol; Cholinergic Antagonists; Glyburide; Hexamethonium; Humans; Ileum; Male; Melatonin; Muscarinic Antagonists; Muscle Contraction; Neuromuscular Depolarizing Agents; Nitrendipine; Phentolamine; Rats; Rats, Wistar; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Verapamil | 1997 |
Calcium is required for swimming by the nonflagellated cyanobacterium Synechococcus strain WH8113.
Topics: Calcium; Calcium Channel Blockers; Calcium Chloride; Cations, Divalent; Chelating Agents; Cyanobacteria; Edetic Acid; Egtazic Acid; Nitrendipine; Terbium; Verapamil | 1997 |
Parathyroid hormone stimulates calcium influx and the cAMP messenger system in rat enterocytes.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Calcium; Calcium Channel Blockers; Cells, Cultured; Cyclic AMP; Duodenum; Intestinal Mucosa; Kinetics; Nitrendipine; Rats; Rats, Wistar; Second Messenger Systems; Teriparatide; Thionucleotides; Verapamil | 1997 |
Effect of Ca2+-channel blockers on isoprenaline-induced desensitization in rat trachea.
Topics: Animals; Calcium Channel Blockers; Carbachol; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nitrendipine; Rats; Rats, Wistar; Trachea; Verapamil | 1997 |
Effects of intracavernous calcium channel blockers in dogs.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Heart Rate; Instillation, Drug; Male; Nifedipine; Nitrendipine; Penile Erection; Pressure; Vasodilator Agents; Verapamil | 1997 |
Combined potassium and calcium channel antagonistic activities as a basis for neutral frequency dependent increase in action potential duration: comparison between BRL-32872 and azimilide.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzamides; Calcium Channel Blockers; Electric Stimulation; Guinea Pigs; Hydantoins; Imidazoles; Imidazolidines; In Vitro Techniques; Male; Membrane Potentials; Nitrendipine; Papillary Muscles; Piperazines; Piperidines; Potassium Channel Blockers; Pyridines; Random Allocation; Ryanodine; Verapamil | 1998 |
Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Calcium Channel Blockers; CHO Cells; Cricetinae; Cytotoxins; Dihydropyridines; Drug Resistance, Multiple; Fibroblasts; Nicardipine; Nimodipine; Nitrendipine; Protein Binding; Verapamil; Vinblastine | 1998 |
Effects of various Ca2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat.
Topics: Analgesics, Opioid; Animals; Binding Sites; Blood Pressure; Calcium Channel Blockers; Cerebral Cortex; Drug Interactions; Drug Tolerance; Male; Morphine; Nifedipine; Nimodipine; Nitrendipine; Rats; Rats, Wistar; Substance-Related Disorders; Tritium; Verapamil | 1998 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Elapid Venoms; Endoplasmic Reticulum; Enzyme Inhibitors; Flufenamic Acid; Glioma; Humans; Imidazoles; Ion Transport; Masoprocol; Neoplasm Proteins; Nicardipine; Nimodipine; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Peptides; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Ryanodine; Thapsigargin; Tumor Cells, Cultured; Verapamil | 1999 |
Effects of the calcium antagonists verapamil and nitrendipine on carbamazepine withdrawal.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Convulsants; Male; Nitrendipine; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome; Verapamil | 1999 |
Functional alteration of dihydropyridine-sensitive Ca(2+) channels in the adrenal glomerulosa of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Radioisotopes; Cell Membrane; Female; Nifedipine; Nitrendipine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tritium; Verapamil; Zona Glomerulosa | 2000 |
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR.
Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil | 2000 |
Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Chloride Channels; Dihydropyridines; Drug Interactions; Glycine; Neural Inhibition; Neurons; Nicardipine; Nifedipine; Nitrendipine; Rats; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Synaptic Transmission; Verapamil | 2001 |
Bending the MDCK cell primary cilium increases intracellular calcium.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line; Cell Polarity; Cilia; Dogs; Enzyme Inhibitors; Epithelial Cells; Fluorescent Dyes; Heptanol; Kidney Tubules, Collecting; Membrane Potentials; Microscopy, Confocal; Nitrendipine; Stress, Mechanical; Verapamil | 2001 |
Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae.
Topics: Alanine; Animals; Biguanides; Calcium Channel Blockers; Cattle; D-Aspartic Acid; Diltiazem; Dizocilpine Maleate; Drug Synergism; Glucose; Glutamic Acid; Glycine; Humans; Kainic Acid; N-Methylaspartate; Nitrendipine; omega-Conotoxins; Perfusion; Piperidines; Polyamines; Receptors, Glutamate; Retina; Tritium; Verapamil | 2003 |
Thyroid hormone export from cells: contribution of P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cell Line; Cell Membrane; Dogs; Drug Resistance, Multiple; Iodine Radioisotopes; Kidney; Nitrendipine; Piperidines; Pyridines; Transfection; Triiodothyronine; Verapamil | 2005 |
Effect of L-type calcium channel antagonists on spermine-induced CNS excitation in vivo.
Topics: Amines; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System; Convulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Mice; Neurodegenerative Diseases; Neurons; Nisoldipine; Nitrendipine; Spermine; Synapses; Synaptic Transmission; Verapamil | 2005 |
Effects of angiotensin II blockade on inflammation-induced alterations of pharmacokinetics and pharmacodynamics of calcium channel blockers.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; C-Reactive Protein; Calcium Channel Blockers; Calcium Channels, L-Type; Drug Interactions; Inflammation; Male; Nitrendipine; Rats; Rats, Sprague-Dawley; Tetrazoles; Valine; Valsartan; Verapamil | 2008 |
A potential calcium antagonist and its antihypertensive effects.
Topics: Animals; Antihypertensive Agents; Aorta; Apiaceae; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Membrane; Chromatography; Furocoumarins; Nitrendipine; Plant Extracts; Rats; Rats, Inbred Strains; Rats, Wistar; Vasodilation; Verapamil | 2011 |
Evaluation of the inhibitory effects of antihypertensive drugs on human carboxylesterase in vitro.
Topics: Antihypertensive Agents; Benzimidazoles; Benzoates; Carboxylesterase; Diltiazem; Drug Interactions; Humans; Imidazolidines; Liver; Nitrendipine; Telmisartan; Verapamil | 2013 |
Distinct Ca2+ channels maintain a high motility state of the sperm that may be needed for penetration of egg jelly of the newt, Cynops pyrrhogaster.
Topics: Acrosome Reaction; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Extracts; Female; Hypotonic Solutions; Male; Mibefradil; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nitrendipine; Ovum; Salamandridae; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Time Factors; Verapamil | 2013 |
[Ca2+]i oscillations in ASM: relationship with persistent airflow obstruction in asthma.
Topics: Adult; Aged; Asthma; Biopsy; Caffeine; Calcium Signaling; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Muscle, Smooth; Nitrendipine; Pulmonary Disease, Chronic Obstructive; Respiratory Muscles; Severity of Illness Index; Verapamil; Vital Capacity | 2014 |