nitrendipine has been researched along with prazosin in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (37.14) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 8 (22.86) | 29.6817 |
| 2010's | 9 (25.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Sen, S; Sinha, N | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Felbel, J; Hofmann, F; Peper, K; Welling, A | 1 |
| Dhalla, NS; Lee, SL | 1 |
| Blue, DR; Clarke, DE; Vimont, RL | 1 |
| Allen, J; Forman, A; Maigaard, S; Skajaa, K | 1 |
| Colucci, WS; Powers, RE | 1 |
| Bhalla, RC; Butters, CA; Sharma, RV | 1 |
| Bowling, N; Gengo, PJ; Hayes, JS; Wyss, VL | 1 |
| Bune, A; Chalmers, J; Heath, W; Jackson, B; Johnston, C; Mashford, ML; McGrath, B; West, M; Westwood, B; Wing, L | 1 |
| Decker, N; Delgado, A; Leclerc, G; Marciniak, G; Schwartz, J; Velly, J | 1 |
| Anderson, A; Gibson, J; Jackson, B; Morgan, TO | 1 |
| Jackson, B; Johnston, CI; McGrath, BP | 1 |
| Berger, J; Blumrich, W; Bouzo, H; Brandl, K; Braun, S; Laukaitis, A; Müller, G; Nechwatal, W; Ryba, W; Schreiegg, J | 1 |
| Lindner, UK; Stafunsky, M; von Manteuffel, GE | 1 |
| Nechwatal, W | 1 |
| Kanaide, H; Nakamura, M; Nishimura, J | 1 |
| Pedrinelli, R; Tarazi, RC | 1 |
| Lasova, LS; Mutafova-Yambolieva, VN; Venkova, KM | 1 |
| Anselmi, E; Bermejo, A; Cabedo, N; Catret, M; Cortes, D; D'Ocon, P; Elorriaga, M; Ivorra, MD; Magraner, J; Tur, R | 1 |
5 trial(s) available for nitrendipine and prazosin
| Article | Year |
|---|---|
Felodipine compared to prazosin as additional therapy to a beta-blocking drug.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Prazosin; Pulse; Random Allocation | 1987 |
Felodipine versus prazosin as an addition to a beta-blocker in the treatment of essential hypertension. The Australian Multicentre Study.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Posture; Prazosin; Random Allocation | 1987 |
Hormonal and blood pressure responses to tilting in beta-blocked essential hypertension treated with felodipine or prazosin.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Prazosin; Pulse; Renin; Vasopressins | 1987 |
A double-blind comparative study of doxazosin and nitrendipine in patients with mild-to-moderate essential hypertension.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hypertension; Lipids; Male; Middle Aged; Nitrendipine; Prazosin | 1988 |
[Doxazosin and nitrendipine. A double-blind comparative study in patients with mild to moderate hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Prazosin | 1987 |
30 other study(ies) available for nitrendipine and prazosin
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Hormonal regulation of calcium current in freshly isolated airway smooth muscle cells.
Topics: Albuterol; Animals; Calcium Channels; Cattle; Cesium; Chlorides; Cyclic AMP; Egtazic Acid; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hormones; In Vitro Techniques; Isoproterenol; Muscle, Smooth; Nitrendipine; Phentolamine; Potassium Chloride; Prazosin; Propranolol; Tetraethylammonium; Tetraethylammonium Compounds; Thionucleotides; Trachea | 1992 |
Ca(2+)-channels and adrenoceptors in diabetic skeletal muscle.
Topics: Animals; Calcium Channels; Diabetes Mellitus, Experimental; Dihydroalprenolol; Kinetics; Male; Muscles; Nitrendipine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reference Values | 1992 |
Evidence for a noradrenergic innervation to alpha 1A-adrenoceptors in rat kidney.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Calcium Channels; Clonidine; In Vitro Techniques; Kidney; Male; Nitrendipine; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction | 1992 |
Effects of vasodilators on isolated human uteroplacental arteries.
Topics: Angiotensin II; Arteries; Chorionic Villi; Dinoprost; Female; Humans; Hydralazine; Labetalol; Nitrendipine; Norepinephrine; Potassium; Prazosin; Pregnancy; Uterus; Vasoconstriction; Vasodilator Agents; Vasopressins | 1991 |
An increase in putative voltage dependent calcium channel number following reserpine treatment.
Topics: Animals; Catecholamines; Ion Channels; Male; Membrane Potentials; Muscle, Smooth; Nifedipine; Nitrendipine; Prazosin; Rats; Receptors, Adrenergic, alpha; Reserpine; Seminal Vesicles; Verapamil | 1985 |
Alterations in the plasma membrane properties of the myocardium of spontaneously hypertensive rats.
Topics: Adenosine Triphosphatases; Animals; Cardiomegaly; Cell Membrane; Ion Channels; Male; Myocardium; Nifedipine; Nitrendipine; Ouabain; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Sodium-Potassium-Exchanging ATPase | 1986 |
Effects of prolonged phenylephrine infusion on cardiac adrenoceptors and calcium channels.
Topics: Animals; Binding Sites; Calcium; Dihydroalprenolol; Heart; Ion Channels; Kinetics; Male; Myocardial Contraction; Myocardium; Nitrendipine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic | 1988 |
New 1,4-dihydropyridine derivatives combining calcium antagonism and alpha-adrenolytic properties.
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Chloride; Cerebral Cortex; Chemical Phenomena; Chemistry; Coronary Vessels; Dihydropyridines; Guinea Pigs; Male; Molecular Structure; Muscle Contraction; Nitrendipine; Prazosin; Rats; Receptors, Adrenergic, alpha; Swine; Vas Deferens; Yohimbine | 1989 |
The addition of doxazosin to the treatment regimen of hypertensive patients not responsive to nifedipine.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease; Doxazosin; Drug Resistance; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Prazosin | 1988 |
Characteristics of adrenoceptors and [3H]nitrendipine receptors of porcine vascular smooth muscle: differences between coronary artery and aorta.
Topics: Animals; Aorta; Binding Sites; Calcium Channels; Coronary Vessels; Dihydroalprenolol; Iodocyanopindolol; Muscle, Smooth, Vascular; Nitrendipine; Pindolol; Prazosin; Receptors, Adrenergic; Receptors, Nicotinic; Swine; Tritium; Yohimbine | 1987 |
Interference of calcium entry blockade in vivo with pressor responses to alpha-adrenergic stimulation: effects of two unrelated blockers on responses to both exogenous and endogenously released norepinephrine.
Topics: Adrenergic alpha-Agonists; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electric Stimulation; Female; Nifedipine; Nitrendipine; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Vasoconstriction; Verapamil; Yohimbine | 1984 |
Atrial natriuretic peptide inhibits the purinergic and not the adrenergic component of electrically induced contractile responses in guinea pig vas deferens.
Topics: Adenosine Triphosphate; Adrenergic Antagonists; Animals; Atrial Natriuretic Factor; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Naloxone; Neurotransmitter Agents; Nitrendipine; Phenylephrine; Prazosin; Receptors, Adrenergic; Receptors, Purinergic; Vas Deferens; Verapamil; Yohimbine | 1993 |
Mechanism of vascular relaxation by thaligrisine: functional and binding assays.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Aorta, Thoracic; Arteries; Binding Sites; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Diltiazem; Female; In Vitro Techniques; Membranes; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrendipine; Norepinephrine; Potassium Chloride; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Tail; Trees; Tritium; Vasoconstrictor Agents | 2000 |