nitrendipine has been researched along with nimodipine in 87 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 29 (33.33) | 18.7374 |
1990's | 30 (34.48) | 18.2507 |
2000's | 14 (16.09) | 29.6817 |
2010's | 12 (13.79) | 24.3611 |
2020's | 2 (2.30) | 2.80 |
Authors | Studies |
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Dietel, M; Höllt, V; Kouba, M; Vogt, G | 1 |
Böcker, RH; Guengerich, FP | 1 |
Janis, RA; Triggle, DJ | 1 |
Jacobson, KA; Jiang, JL; Melman, N; Olah, ME; Stiles, GL; van Rhee, AM | 1 |
Topliss, JG; Yoshida, F | 1 |
Lipscombe, D; Xu, W | 1 |
Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Cuddon, P; Fleming, A; Floto, RA; Goldsmith, P; Jahreiss, L; O'Kane, CJ; Pask, D; Rubinsztein, DC; Saiki, S; Sarkar, S; Siddiqi, FH; Ttofi, EK; Williams, A | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D | 1 |
Cao, S; Chang, CC; Dunne, SF; Kai, L; Kang, S; Luan, CH; Pandey, P; Silverman, RB; Surmeier, DJ; Tian, X | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Reimão, JQ; Scotti, MT; Tempone, AG | 1 |
Sun, H | 1 |
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
Chen, J; Han, C; Huang, MX; Li, Z; Liu, RD; Luo, HB; Tian, YJ; Wu, Y; Xie, X; Yang, YY; Yuan, Y | 1 |
Mason, RP; Moisey, DM; Shajenko, L | 1 |
Gual, A; López, A; Palacios-Araus, L; Palés, J | 1 |
Lipsey, LR; Reiss, M; Zhou, ZL | 1 |
Little, HJ; Littleton, JM; Whittington, MA | 1 |
Regan, LJ | 1 |
Ahr, G; Baunack, AR; Konrad-Dalhoff, I; Kraft, H; Kuhlmann, J; Rämsch, KD; Schmitz, H; Weihrauch, TR | 1 |
Butterworth, AR; Dolin, SJ; Little, HJ; Patch, TL; Siarey, RJ; Whittington, MA | 1 |
Mehta, AK; Ticku, MK | 1 |
Augustine, GJ; Buchanan, J; Nuño, CM; Sanchez, ME | 1 |
Batra, S | 1 |
Carpenter, CL; Greenberg, DA; Messing, RO | 1 |
Andresen, MC; Kunze, DL; Torres, LA | 1 |
Brown, AM; Brush, K; Hamilton, SL; Schwartz, A; Yatani, A | 1 |
Bellemann, P; Garthoff, B | 1 |
Dolin, SJ; Halsey, MJ; Hunter, AB; Little, HJ | 1 |
Dolin, SJ; Little, HJ | 1 |
Ferry, DR; Glossmann, H; Goll, A; Linn, T | 1 |
Brush, KL; Hamilton, SL; Hawkes, MJ; Perez, M; Pratt, DR | 1 |
Kamei, C; Kurokawa, K; Tasaka, K | 1 |
Bolger, GT; Ruzycky, A; Triggle, DJ; Yousif, FB | 1 |
Baky, S; Nademanee, K; Singh, BN | 1 |
Dolin, SJ; Halsey, MJ; Little, HJ | 1 |
Graefe, KH; Rämsch, KD; Scherling, D; Sommer, J; Ziegler, R | 1 |
Bellemann, P | 1 |
Kirley, TL; Schwartz, A | 1 |
Kojima, I; Kojima, K; Rasmussen, H | 1 |
Grupp, G; Grupp, IL; Schwartz, A; Vaghy, PL; Williams, JS | 1 |
Ferry, DR; Glossmann, H; Goll, A | 1 |
Gould, RJ; Murphy, KM; Snyder, SH | 1 |
Itoh, T; Kanmura, Y; Kuriyama, H; Makita, Y; Suzuki, H | 1 |
Freedman, SB; Miller, RJ | 1 |
Janis, RA; Pan, M | 1 |
Barr, EM; Daniell, LC; Leslie, SW | 1 |
Bolger, GT; Gengo, P; Janis, RA; Klockowski, R; Luchowski, E; Siegel, H; Triggle, AM; Triggle, DJ | 1 |
Bolger, GT; Janis, RA; Maurer, SC; Sarmiento, JG; Triggle, DJ | 1 |
Bellemann, P; Ferry, D; Glossmann, H; Lübbecke, F | 1 |
Morales Mulia, M; Morán, J; Pasantes-Morales, H; Sánchez-Olea, R | 1 |
Filloux, FM; Fitts, RC; Skeen, GA; White, HS | 1 |
Kaur, AH; Mathur, SK; Singh, J; Srivastava, RK | 1 |
Floersheim, GL; Racine, C | 1 |
Szabó, C; Thiemermann, C; Vane, JR | 1 |
Mintz, IM | 1 |
Floersheim, GL | 1 |
Eichelbaum, M; Fischer, C; Heuck, K; Mück, W; Schönberger, F | 1 |
Kaur, AH; Mathur, SK; Singh, J | 1 |
Gilar, M; Tesarová, E; Uhrová, M | 1 |
Okopién, B; Trzeciak, HI | 1 |
Bansal, S; Kaur, AH; Lal, H; Singh, J | 1 |
Andreas, K; Bräter, M; Li, SN | 1 |
Garrigos, M; Orlowski, S; Pascaud, C | 1 |
Antkiewicz-Michaluk, L; Karolewicz, B; Michaluk, J; Vetulani, J | 1 |
Jaroszkiewicz, E; Marciniec, B; Ogrodowczyk, M; Patterson, LH; Taiwo, FA | 1 |
Guan, Z; Saqr, HE; Stokes, BT; Yates, AJ | 1 |
Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S | 1 |
Balakrishnan, S; Bhargava, VK; Pandhi, P | 1 |
Gatch, MB; Lal, H; Wallis, CJ | 1 |
de Souza Pereira, R | 1 |
Camargo, C; Núñez-Vergara, LJ; Ortiz, ME; Squella, JA | 1 |
Dilger, EK; Guido, W; Lo, FS; Ziburkus, J | 1 |
Chepur, SV; Rybakova, GI; Sotnikov, OS; Vasiagina, NY | 1 |
Krzemiński, TF; Mitręga, KA; Porc, M; Varghese, B | 1 |
Chudoba, D; Drużbicki, K; Jarek, M; Jenczyk, J; Kiwilsza, A; Mielcarek, J; Pajzderska, A; Wąsicki, J | 1 |
5 review(s) available for nitrendipine and nimodipine
Article | Year |
---|---|
New developments in Ca2+ channel antagonists.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Humans; Ion Channels; Muscle Relaxation; Muscle, Smooth; Potassium; Sodium; Structure-Activity Relationship; Substrate Specificity | 1983 |
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels | 2010 |
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
Second-generation calcium antagonists: search for greater selectivity and versatility.
Topics: Animals; Bepridil; Calcium Channel Blockers; Cinnarizine; Electrophysiology; Flunarizine; Heart; Humans; Lidoflazine; Muscle, Smooth, Vascular; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyrrolidines; Structure-Activity Relationship | 1985 |
Are dihydropyridine binding sites voltage sensitive calcium channels?
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Ion Channels; Muscle, Smooth; Muscles; Myocardium; Neurons; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines | 1984 |
1 trial(s) available for nitrendipine and nimodipine
Article | Year |
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Effect of the calcium antagonists nifedipine, nitrendipine, nimodipine and nisoldipine on oesophageal motility in man.
Topics: Administration, Oral; Adult; Calcium Channel Blockers; Double-Blind Method; Esophagogastric Junction; Esophagus; Humans; Male; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Peristalsis; Pressure | 1991 |
81 other study(ies) available for nitrendipine and nimodipine
Article | Year |
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Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Biological Transport; Calcium Channel Blockers; Cell Line; Dihydropyridines; Drug Resistance; Haplorhini; Immunoblotting; Membrane Glycoproteins; Mice; RNA, Messenger; Stereoisomerism; Verapamil; Vinblastine | 1992 |
Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450.
Topics: Chemical Phenomena; Chemistry; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Microsomes, Liver; NADP; Nifedipine; Oxidation-Reduction | 1986 |
Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Dihydropyridines; Enzyme Inhibitors; Guinea Pigs; Humans; Isradipine; Molecular Structure; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship | 1996 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alternative Splicing; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Kidney; Membrane Potentials; Molecular Sequence Data; Nimodipine; Oocytes; Patch-Clamp Techniques; Protein Subunits; Rats; Signal Transduction; Transfection; Xenopus | 2001 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Topics: Animals; Autophagy; Calcium Channels, L-Type; Clonidine; Cyclic AMP; Humans; Huntington Disease; Imidazoline Receptors; Minoxidil; Protein Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Type C Phospholipases; Verapamil | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Dicarboxylic Acids; Dihydropyridines; Humans; Inhibitory Concentration 50; Molecular Structure; Nifedipine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction | 2012 |
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Structural Modifications of Nimodipine Lead to Novel PDE1 Inhibitors with Anti-pulmonary Fibrosis Effects.
Topics: Animals; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Idiopathic Pulmonary Fibrosis; Nimodipine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats | 2022 |
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil | 1992 |
Effects of dihydropyridines and inorganic calcium blockers on aggregation and on intracellular free calcium in platelets.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Female; Humans; Male; Nimodipine; Nisoldipine; Nitrendipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium; Thrombin | 1991 |
Extracellular calcium-dependent regulation of transmembrane calcium fluxes in murine keratinocytes.
Topics: Animals; Calcium; Calcium Channels; Cell Line; Cobalt; Keratinocytes; Lanthanum; Mice; Nickel; Nimodipine; Nitrendipine; Verapamil | 1991 |
Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal; doses required, stereospecificity and actions of Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Ethanol; Isradipine; Male; Mice; Nimodipine; Nitrendipine; Oxadiazoles; Stereoisomerism; Substance Withdrawal Syndrome; Time Factors | 1990 |
Voltage-dependent calcium currents in Purkinje cells from rat cerebellar vermis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Barium; Calcium Channels; Cell Separation; Dihydropyridines; Electric Conductivity; Electrophysiology; Nickel; Nimodipine; Nitrendipine; Purkinje Cells; Rats | 1991 |
Chronic dihydropyridine treatment can reverse the behavioural consequences of and prevent adaptations to, chronic ethanol treatment.
Topics: Adaptation, Psychological; Administration, Inhalation; Animals; Behavior, Animal; Bicuculline; Brain; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Ethanol; Isradipine; Male; Mice; Mice, Inbred C57BL; Nimodipine; Nitrendipine; Seizures; Substance Withdrawal Syndrome | 1991 |
Role of N-methyl-D-aspartate (NMDA) receptors in experimental catalepsy in rats.
Topics: Animals; Aspartic Acid; Baclofen; Bromocriptine; Catalepsy; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Interactions; Haloperidol; Male; N-Methylaspartate; Nimodipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Scopolamine | 1990 |
Contractions of the squid stellate ganglion.
Topics: Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cytoskeleton; Decapodiformes; Ganglia, Sympathetic; Manganese; Microscopy, Electron; Movement; Nimodipine; Nitrendipine; Sodium; Synapses; Tetrodotoxin | 1990 |
Characterization of [3H]-nitrendipine binding to uterine smooth muscle plasma membrane and its relevance to inhibition of calcium entry.
Topics: Animals; Binding, Competitive; Calcium; Cell Fractionation; Cell Membrane; Diethylstilbestrol; Diltiazem; Edetic Acid; Egtazic Acid; Female; Ion Channels; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Uterus | 1985 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil | 1985 |
Do calcium antagonists act directly on calcium channels to alter baroreceptor function?
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Ion Channels; Nifedipine; Nimodipine; Nitrendipine; Pressoreceptors; Rats; Rats, Inbred Strains; Verapamil | 1986 |
A comparison between the binding and electrophysiological effects of dihydropyridines on cardiac membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Heart; Ion Channels; Isradipine; Kinetics; Membrane Potentials; Membranes; Myocardium; Nicotinic Acids; Nimodipine; Nitrendipine; Oxadiazoles; Pyridines; Stereoisomerism; Structure-Activity Relationship | 1987 |
Effects of salt loading and nitrendipine on dihydropyridine receptors in hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Calcium Channel Blockers; Calcium Channels; Hypertension; Membranes; Myocardium; Nimodipine; Nitrendipine; Rats; Rats, Inbred WKY; Receptors, Nicotinic; Sodium, Dietary | 1987 |
Anticonvulsant profile of the dihydropyridine calcium channel antagonists, nitrendipine and nimodipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Aspartic Acid; Atmospheric Pressure; Calcium Channel Blockers; Electrophysiology; Male; N-Methylaspartate; Nimodipine; Nitrendipine; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Strychnine | 1988 |
Are changes in neuronal calcium channels involved in ethanol tolerance?
Topics: Alcoholism; Animals; Behavior, Animal; Brain; Calcium Channels; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Hexamethonium; Hexamethonium Compounds; Male; Nimodipine; Nitrendipine; Radioligand Assay; Rats | 1989 |
Molecular approach to the calcium channel.
Topics: Animals; Benzothiazoles; Binding Sites; Brain; Calcium; Cattle; Chemical Phenomena; Chemistry; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles; Thiazoles; Verapamil | 1985 |
Low affinity binding sites for 1,4-dihydropyridines in mitochondria and in guinea pig ventricular membranes.
Topics: Animals; Calcium Channels; Cations, Divalent; Cell Membrane; Diltiazem; Guinea Pigs; Heart Ventricles; Hot Temperature; Mitochondria; Myocardium; Nimodipine; Nitrendipine; Osmolar Concentration; Protein Denaturation; Receptors, Nicotinic; Sodium Chloride; Verapamil | 1987 |
Hypotensive effects of dihydropyridine derivatives.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Hydralazine; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1985 |
Ca2+ channel antagonist actions in bladder smooth muscle: comparative pharmacologic and [3H]nitrendipine binding studies.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Gallopamil; Guinea Pigs; In Vitro Techniques; Male; Microsomes; Muscarine; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Urinary Bladder | 1985 |
Calcium channel antagonists decrease the ethanol withdrawal syndrome.
Topics: Animals; Calcium Channel Blockers; Diazepam; Ethanol; Flunarizine; Male; Motor Activity; Nimodipine; Nitrendipine; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Verapamil | 1986 |
Pharmacokinetics and metabolism of calcium-blocking agents nifedipine, nitrendipine, and nimodipine.
Topics: Biological Availability; Female; Half-Life; Humans; Individuality; Kinetics; Male; Nifedipine; Nimodipine; Nitrendipine | 1986 |
Interaction of the calcium channel activating 3H-BAY K 8644 and inhibiting 3H-verapamil with specific receptor sites on cultured beating myocardial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Calcium Channel Blockers; Cells, Cultured; Kinetics; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Receptors, Drug; Verapamil | 1984 |
Solubilization and affinity labeling of a dihydropyridine binding site from skeletal muscle: effects of temperature and diltiazem on [3H]dihydropyridine binding to transverse tubules.
Topics: Affinity Labels; Animals; Benzazepines; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Diltiazem; Intracellular Membranes; Kinetics; Microsomes; Microtubules; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rabbits; Receptors, Nicotinic; Temperature | 1984 |
Dihydropyridine calcium agonist and antagonist effects on aldosterone secretion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Dantrolene; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium; Stimulation, Chemical | 1984 |
Effects of dihydropyridine calcium channel modulators in the heart: pharmacological and radioligand binding correlations.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rats; Stimulation, Chemical | 1984 |
Differential labelling of putative skeletal muscle calcium channels by [3H]-nifedipine, [3H]-nitrendipine, [3H]-nimodipine and [3H]-PN 200 110.
Topics: Animals; Calcium Channel Blockers; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Kinetics; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles | 1983 |
A simple sensitive radioreceptor assay for calcium antagonist drugs.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cattle; Cell Membrane; Cerebral Cortex; Diltiazem; In Vitro Techniques; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Prenylamine; Radioligand Assay; Receptors, Nicotinic; Verapamil | 1983 |
Effects of nifedipine derivatives on smooth muscle cells and neuromuscular transmission in the rabbit mesenteric artery.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Female; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Rabbits; Synaptic Transmission | 1983 |
Stimulation of Na+,K+-ATPase of isolated smooth muscle membranes by the Ca2+ channel inhibitors, nimodipine and nitrendipine.
Topics: Animals; Brain; Guinea Pigs; Male; Membranes; Muscle, Smooth; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Ouabain; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1984 |
45Ca2+ uptake into rat whole brain synaptosomes unaltered by dihydropyridine calcium antagonists.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Male; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes | 1983 |
Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cinnarizine; Cobalt; Dose-Response Relationship, Drug; Drug Synergism; Flunarizine; Guinea Pigs; Ileum; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines; Structure-Activity Relationship; Verapamil | 1983 |
Binding of [3H]nimodipine to cardiac and smooth muscle membranes.
Topics: Animals; Calcium Channel Blockers; Kinetics; Male; Membranes; Microsomes; Muscle, Smooth; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rats | 1982 |
[3H]-Nimodipine and [3H]-nitrendipine as tools to directly identify the sites of action of 1,4-dihydropyridine calcium antagonists in guinea-pig tissues. Tissue-specific effects of anions and ionic strength.
Topics: Animals; Anions; Binding Sites; Binding, Competitive; Brain; Calcium Channel Blockers; Female; Guinea Pigs; Kidney; Kinetics; Lung; Male; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Organ Specificity; Osmolar Concentration; Pyridines | 1982 |
Inhibition by dihydropyridines of regulatory volume decrease and osmolyte fluxes in cultured astrocytes is unrelated to extracellular calcium.
Topics: Animals; Astrocytes; Calcium; Cells, Cultured; Cerebellum; Dihydropyridines; Dose-Response Relationship, Drug; Nimodipine; Nitrendipine; Rats; Rats, Inbred Strains; Taurine; Water-Electrolyte Balance | 1995 |
The dihydropyridine nitrendipine inhibits [3H]MK 801 binding to mouse brain sections.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Autoradiography; Binding, Competitive; Brain; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Nifedipine; Nimodipine; Nitrendipine; Software; Verapamil | 1994 |
Effect of nitrendipine, nimodipine and nisoldipine on experimentally induced myocardial infarction in rats.
Topics: Animals; Aspartate Aminotransferases; Calcium Channel Blockers; Female; Heart; Isoproterenol; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardium; Nimodipine; Nisoldipine; Nitrendipine; Rats | 1995 |
Calcium antagonist radioprotectors do not reduce radiotherapeutic efficacy in three human tumor xenografts.
Topics: Adenocarcinoma; Animals; Calcium Channel Blockers; Colonic Neoplasms; Diltiazem; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Radiotherapy Dosage; Sarcoma, Ewing; Transplantation, Heterologous; Whole-Body Irradiation | 1995 |
Dihydropyridine antagonists and agonists of calcium channels inhibit the induction of nitric oxide synthase by endotoxin in cultured macrophages.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Oxidoreductases; Animals; Calcium Channel Blockers; Cell Line; Endotoxins; Enzyme Induction; Escherichia coli; Kinetics; Lipopolysaccharides; Macrophages; Mice; Nimodipine; Nisoldipine; Nitrendipine; Nitric Oxide Synthase | 1993 |
Block of Ca channels in rat central neurons by the spider toxin omega-Aga-IIIA.
Topics: Action Potentials; Agatoxins; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Hippocampus; Kinetics; Membrane Potentials; Neurons; Nimodipine; Nitrendipine; omega-Conotoxin GVIA; Peptides; Purkinje Cells; Rats; Spider Venoms; Time Factors | 1994 |
Radioprotective effects of calcium antagonists used alone or with other types of radioprotectors.
Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Diltiazem; Dimethyl Sulfoxide; Drug Combinations; Female; Flunarizine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Verapamil; Zinc | 1993 |
Simultaneous assessment of the intravenous and oral disposition of the enantiomers of racemic nimodipine by chiral stationary-phase high-performance liquid chromatography and gas chromatography/mass spectroscopy combined with a stable isotope technique.
Topics: Administration, Oral; Adult; Carbon Isotopes; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intravenous; Isotope Labeling; Male; Nimodipine; Nitrendipine; Sensitivity and Specificity; Stereoisomerism; Tissue Distribution | 1993 |
Protection of CCL4-induced liver damage in rats by some calcium channel blockers.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Calcium Channel Blockers; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; gamma-Glutamyltransferase; Liver; Male; Necrosis; Nimodipine; Nisoldipine; Nitrendipine; Rats; Rats, Wistar | 1995 |
Enantiomer separation of dihydropyridine calcium antagonists with cyclodextrins as chiral selectors: structural correlation.
Topics: Amlodipine; Buffers; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cyclodextrins; Dihydropyridines; Electrolytes; Electrophoresis, Capillary; Isradipine; Microspheres; Molecular Conformation; Nimodipine; Nisoldipine; Nitrendipine; Sodium Dodecyl Sulfate; Solvents; Stereoisomerism; Surface-Active Agents | 1996 |
Modification of adrenergic reactivity in rat tail artery by dietary lipids and calcium channel antagonists.
Topics: Animals; Arteries; Body Weight; Calcium Channel Blockers; Diet, Atherogenic; Dietary Fats; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nimodipine; Nitrendipine; Norepinephrine; Rats; Rats, Wistar; Regional Blood Flow; Sympathetic Nervous System; Sympathomimetics; Tail | 1996 |
Effect of nitrendipine, nimodipine and nisoldipine on water and electrolytes excretion in rats.
Topics: Animals; Calcium Channel Blockers; Creatinine; Diuresis; Electrolytes; Female; Glomerular Filtration Rate; Male; Nimodipine; Nisoldipine; Nitrendipine; Rats | 1996 |
Nimodipine and nitrendipine inhibit N-type calcium channels in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid (NG 108-15) cells.
Topics: Animals; Bucladesine; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Dihydropyridines; Evoked Potentials; Glioma; Hybrid Cells; Kinetics; Mice; Neuroblastoma; Nimodipine; Nitrendipine; Potassium; Rats | 1997 |
Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Calcium Channel Blockers; CHO Cells; Cricetinae; Cytotoxins; Dihydropyridines; Drug Resistance, Multiple; Fibroblasts; Nicardipine; Nimodipine; Nitrendipine; Protein Binding; Verapamil; Vinblastine | 1998 |
Effects of various Ca2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat.
Topics: Analgesics, Opioid; Animals; Binding Sites; Blood Pressure; Calcium Channel Blockers; Cerebral Cortex; Drug Interactions; Drug Tolerance; Male; Morphine; Nifedipine; Nimodipine; Nitrendipine; Rats; Rats, Wistar; Substance-Related Disorders; Tritium; Verapamil | 1998 |
Free radicals in irradiated drugs: an EPR study.
Topics: Calcium Channel Blockers; Dose-Response Relationship, Radiation; Electron Spin Resonance Spectroscopy; Felodipine; Free Radicals; Gamma Rays; Nifedipine; Nimodipine; Nitrendipine | 1999 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Elapid Venoms; Endoplasmic Reticulum; Enzyme Inhibitors; Flufenamic Acid; Glioma; Humans; Imidazoles; Ion Transport; Masoprocol; Neoplasm Proteins; Nicardipine; Nimodipine; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Peptides; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Ryanodine; Thapsigargin; Tumor Cells, Cultured; Verapamil | 1999 |
Calcium channel activation and self-biting in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior | 1999 |
Anticonvulsant profile of nimodipine and nitrendipine against pentylenetetrazole induced seizures in rats.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Male; Nimodipine; Nitrendipine; Pentylenetetrazole; Rats; Seizures; Valproic Acid | 1999 |
Effects of calcium channel blockers on pentylenetetrazol drug discrimination in rats.
Topics: Animals; Calcium Channel Blockers; Diet; Discrimination, Psychological; Ethanol; Kinetics; Male; Nimodipine; Nitrendipine; Pentylenetetrazole; Rats; Rats, Long-Evans; Self Administration; Substance Withdrawal Syndrome | 2001 |
The use of calcium blockers to study biochemical behaviour of Saccharomyces cerevisiae cells.
Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cytochrome c Group; Membrane Potentials; NADP; Nimodipine; Nitrendipine; Oxidation-Reduction; Oxygen; Saccharomyces cerevisiae | 2001 |
Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide.
Topics: Calcium Channel Blockers; Felodipine; Nifedipine; Nimodipine; Nitrendipine; Superoxides | 2004 |
LTD and LTP at the developing retinogeniculate synapse.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Bicuculline; Biophysics; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Geniculate Bodies; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Nimodipine; Nitrendipine; Rats; Rats, Long-Evans; Retina; Synapses; Time Factors; Visual Pathways | 2009 |
Inhibition of contractions of nerve processes in calcium-free medium.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Movement; Cobalt; Isotonic Solutions; Lymnaea; Neurites; Nimodipine; Nitrendipine; Ringer's Solution | 2010 |
Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine.
Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Dihydropyridines; Heart; Hemodynamics; Male; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2012 |
In search of the mutual relationship between the structure, solid-state spectroscopy and molecular dynamics in selected calcium channel blockers.
Topics: Calcium Channel Blockers; Crystallization; Dihydropyridines; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Nifedipine; Nimodipine; Nitrendipine; Quantum Theory; Spectrophotometry, Infrared; X-Ray Diffraction | 2016 |