nitrendipine and metoprolol

nitrendipine has been researched along with metoprolol in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199018 (51.43)18.7374
1990's4 (11.43)18.2507
2000's6 (17.14)29.6817
2010's7 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bohle, K; Deleu, D1
Adam, W; Anderson, A; Cripps, J; Morgan, TO1
Armstrong, VW; Buhr-Schinner, H; Kandt, M; Scheler, F; Schoel, G; Schrader, J; Warneke, G1
Horton, R; Nordlander, M; Thalén, P1
Buhr-Schinner, H; Haupt, A; Kandt, M; Scheler, F; Schoel, G; Schrader, J; Schuster, S; Warneke, G1
Buhr-Schinner, H; Haupt, A; Kandt, M; Scheler, F; Schoel, G; Schrader, J; Warneke, G1
Nordborg, C3
Geller, M; Kirch, W; Mönig, H; Ohnhaus, EE; Santos, SR; Stenzel, J1
Chow, J1
Groom, P; Peers, E; Richardson, PD; Simpson, RJ; Singh, B; Ward, DE1
Burton, RH; Davis, RH; Freeling, P; Goves, JR; Orme-Smith, EA1
Burton, RH; Davis, RH; Freeling, P; Goves, JR; Graham-Evans, JN; Orne-Smith, EA; Osborne, CJ; Ward, DE1
Amery, A; De Schaepdryver, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J1
Friberg, P; Nordlander, M; Wåhlander, H1
Hardebo, JE; Kåhrström, J; Nordborg, C1
Amery, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J1
Amery, A; Fagard, R; Staessen, J1
Jack, DB; Kendall, MJ; Laugher, S; Smith, SR; Wilkins, MR1
Wang, J; Xie, J; Yang, H1
Chen, Z; Hao, G; Li, Y; Ma, L; Wang, X; Wang, Z; Zhang, L; Zhao, X; Zhu, M1

Trials

11 trial(s) available for nitrendipine and metoprolol

ArticleYear
The use of carvedilol in elderly hypertensive patients.
    European journal of clinical pharmacology, 1990, Volume: 38 Suppl 2

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Blood Pressure; Carbazoles; Carvedilol; Female; Half-Life; Heart Rate; Humans; Hypertension; Lipids; Male; Metoprolol; Middle Aged; Multicenter Studies as Topic; Nitrendipine; Pindolol; Propanolamines; Random Allocation; Single-Blind Method

1990
Comparison of the antihypertensive efficiency of nitrendipine, metoprolol, mepindolol and enalapril using ambulatory 24-hour blood pressure monitoring.
    The American journal of cardiology, 1990, Oct-15, Volume: 66, Issue:12

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Enalapril; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Monitoring, Physiologic; Nitrendipine; Pindolol

1990
[24-hour blood pressure behavior in patients with untreated and treated hypertension in comparison with normotensive patients].
    Zeitschrift fur Kardiologie, 1989, Volume: 78, Issue:12

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitors; Circadian Rhythm; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Nitrendipine; Pindolol; Randomized Controlled Trials as Topic

1989
[Ambulatory continuous 24-hour blood pressure monitoring in the diagnosis and therapy of arterial hypertension and modification by the antihypertensive agents enalapril, metoprolol, mepindolol and nitrendipine].
    Klinische Wochenschrift, 1988, Sep-15, Volume: 66, Issue:18

    Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Circadian Rhythm; Clinical Trials as Topic; Enalapril; Humans; Hypertension; Metoprolol; Microcomputers; Monitoring, Physiologic; Nitrendipine; Pindolol

1988
Influence of nitrendipine and verapamil on plasma levels, urinary excretion, and beta-blocking effect of metoprolol.
    Cardiovascular drugs and therapy, 1988, Volume: 2, Issue:2

    Topics: Adult; Female; Heart Rate; Humans; Male; Metoprolol; Nitrendipine; Verapamil

1988
A double-blind comparison of felodipine and hydrochlorothiazide added to metoprolol to control hypertension.
    European journal of clinical pharmacology, 1988, Volume: 34, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dizziness; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Headache; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Nitrendipine; Random Allocation; Time Factors

1988
Control of hypertension in elderly patients with felodipine and metoprolol: a double-blind, placebo-controlled clinical trial.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:4

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Felodipine; Heart Rate; Humans; Hypertension; Metoprolol; Nitrendipine; Random Allocation

1987
Hypertension in the elderly. Its diagnosis in general practice and treatment with felodipine and metoprolol.
    Drugs, 1987, Volume: 34 Suppl 3

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Felodipine; Heart Rate; Humans; Hypertension; Metoprolol; Nitrendipine; Random Allocation

1987
Pharmacokinetic interactions between felodipine and metoprolol.
    European journal of clinical pharmacology, 1987, Volume: 31, Issue:5

    Topics: Adult; Double-Blind Method; Drug Interactions; Felodipine; Half-Life; Humans; Kinetics; Male; Metoprolol; Nitrendipine; Time Factors

1987
Hypertension control improved through patient education. Chinese PEP Investigators.
    Chinese medical journal, 1998, Volume: 111, Issue:7

    Topics: Aged; Antihypertensive Agents; Female; Follow-Up Studies; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nitrendipine; Patient Education as Topic; Relaxation Therapy

1998
Cost-effectiveness of nitrendipine and hydrochlorothiazide or metoprolol to treat hypertension in rural community health centers in China.
    Journal of hypertension, 2017, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Beijing; Blood Pressure; Community Health Centers; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Health Care Costs; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Nitrendipine; Prospective Studies; Rural Health Services; Young Adult

2017

Other Studies

24 other study(ies) available for nitrendipine and metoprolol

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Metoprolol as antihypertensive drug.
    The American journal of cardiology, 1991, Sep-15, Volume: 68, Issue:8

    Topics: Humans; Hypertension; Lipid Metabolism; Metoprolol; Monitoring, Physiologic; Nitrendipine

1991
Baroreflex control of heart rate and renin release in SHR following administration of felodipine, an antihypertensive Ca2+ antagonist.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Heart Rate; Hypertension; Metoprolol; Nitrendipine; Pressoreceptors; Rats; Rats, Inbred SHR; Renin

1987
The influence of antihypertensive treatment on the mesenteric arterial structure in spontaneously hypertensive rats. A morphometric study.
    Acta physiologica Scandinavica, 1989, Volume: 135, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Heart Rate; Male; Mesenteric Arteries; Metoprolol; Muscle, Smooth, Vascular; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1989
The effects of combining felodipine and metoprolol in moderate to severe hypertension--a one year study.
    Journal of human hypertension, 1988, Volume: 2, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nitrendipine

1988
Effects of felodipine and metoprolol on blood pressure, plasma renin, angiotensin II, aldosterone and catecholamines in hypertensive patients.
    Drugs, 1987, Volume: 34 Suppl 3

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Electrocardiography; Felodipine; Humans; Hypertension; Male; Metoprolol; Nitrendipine; Renin; Time Factors

1987
Influence of antihypertensive treatment on basal cerebral arteries in spontaneously hypertensive rats. A morphometric study.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1988, Volume: 96, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cerebral Arteries; Drug Therapy, Combination; Felodipine; Heart Rate; Hypertension; Metoprolol; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1988
Structural and functional adaptations within the myocardium and coronary vessels after antihypertensive therapy in spontaneously hypertensive rats.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1986, Volume: 4, Issue:3

    Topics: Animals; Coronary Circulation; Coronary Vessels; Felodipine; Hypertension; Metoprolol; Myocardium; Nitrendipine; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Vascular Resistance

1986
Does sympathectomy or antihypertensive treatment affect the morphometry of basal cerebral arteries in spontaneously hypertensive rats?
    Acta physiologica Scandinavica. Supplementum, 1986, Volume: 552

    Topics: Age Factors; Animals; Blood Pressure; Cerebral Arteries; Felodipine; Ganglia, Sympathetic; Hypertension; Metoprolol; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathectomy

1986
Acute haemodynamic and humoral responses to felodipine and metoprolol in mild hypertension.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:1

    Topics: Adult; Aldosterone; Antihypertensive Agents; Calcium Channel Blockers; Catecholamines; Drug Therapy, Combination; Felodipine; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Nitrendipine; Pulmonary Circulation; Renin-Angiotensin System; Vasodilator Agents

1987
The use of Doppler echocardiography to assess the acute haemodynamic response to felodipine and metoprolol in hypertensive patients.
    Journal of hypertension, 1987, Volume: 5, Issue:2

    Topics: Adult; Antihypertensive Agents; Cardiac Output; Echocardiography; Felodipine; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Nitrendipine; Stroke Volume; Vascular Resistance

1987
The influence of antihypertensive treatment on the renal arterial structure in spontaneously hypertensive rats. A morphometric study.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:10

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Heart Rate; Hypertension; Male; Metoprolol; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery

1987