nitrendipine and indomethacin

nitrendipine has been researched along with indomethacin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.00)18.7374
1990's5 (20.00)18.2507
2000's7 (28.00)29.6817
2010's9 (36.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Sen, S; Sinha, N1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Cingi, MI; Erol, K; Ulak, G1
Hyman, AL; Lippton, HL; Ohlstein, EH; Summer, WR1
Allen, J; Andersson, KE; Forman, A; Hansen, V; Lauridsen, V1
Bailey, DG; Bartle, WR; Edgar, B; Hardy, BG; Myers, M1
Burka, JF; Saad, MH1
Lasova, LS; Mutafova-Yambolieva, VN; Venkova, KM1
Enzan, K; Mitchell, MD; Schultz, E; Staub, NC; Stavros, F; Wang, Y1
Beilby, J; Bune, AJ; Chalmers, JP; Goh, SH; Harvey, PJ; Ramsay, A; Russell, AE; Tonkin, AL; Wing, LM1
Bischoff, A; Czyborra, P; Fetscher, C; Jakobs, KH; Meyer Zu Heringdorf, D; Michel, MC1

Trials

2 trial(s) available for nitrendipine and indomethacin

ArticleYear
Effect of indomethacin on the pharmacokinetics and pharmacodynamics of felodipine.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:5

    Topics: Adult; Blood Pressure; Diuresis; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Felodipine; Heart Rate; Hemodynamics; Humans; Indomethacin; Male; Natriuresis; Nitrendipine; Random Allocation; Time Factors; Vasodilator Agents

1988
Effect of indomethacin on blood pressure control during treatment with nitrendipine.
    Blood pressure, 1995, Volume: 4, Issue:5

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Blood Pressure; Body Weight; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Indomethacin; Male; Middle Aged; Nitrendipine

1995

Other Studies

23 other study(ies) available for nitrendipine and indomethacin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Gastroprotective effect of nitrendipine on stress-induced gastric lesions in rats.
    Pharmacology, 1991, Volume: 43, Issue:4

    Topics: Animals; Cold Temperature; Dexamethasone; Female; Immobilization; Indomethacin; Male; Nitrendipine; Peptic Ulcer Hemorrhage; Rats; Stomach Ulcer; Stress, Physiological

1991
Analysis of responses to endothelins in the rabbit pulmonary and systemic vascular beds.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 70, Issue:1

    Topics: Animals; Blood Pressure; Endothelins; Hemodynamics; Indomethacin; Male; Nitrendipine; Pulmonary Circulation; Rabbits; Vascular Resistance; Vasoconstriction

1991
Effects of indomethacin on human placental stem villous arteries.
    Gynecologic and obstetric investigation, 1989, Volume: 27, Issue:3

    Topics: Arteries; Chorionic Villi; Chromatography, Gas; Female; Humans; Indomethacin; Isometric Contraction; Nitrendipine; Potassium; Pregnancy; Prostaglandins F; Serotonin; Vasoactive Intestinal Peptide

1989
Role of calcium in arachidonic acid-induced contractions of guinea pig airways.
    European journal of pharmacology, 1984, Apr-13, Volume: 100, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channel Blockers; Edetic Acid; Gallic Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Lanthanum; Lung; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; SRS-A; Trachea; Verapamil

1984
Atrial natriuretic peptide inhibits the purinergic and not the adrenergic component of electrically induced contractile responses in guinea pig vas deferens.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: Adenosine Triphosphate; Adrenergic Antagonists; Animals; Atrial Natriuretic Factor; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Naloxone; Neurotransmitter Agents; Nitrendipine; Phenylephrine; Prazosin; Receptors, Adrenergic; Receptors, Purinergic; Vas Deferens; Verapamil; Yohimbine

1993
Pulmonary hypertensive response to rabbit blood components in goats: role of thromboxane.
    The American review of respiratory disease, 1993, Volume: 147, Issue:4

    Topics: Animals; Blood Physiological Phenomena; Chlorpheniramine; Female; Goats; Hemodynamics; Hypertension, Pulmonary; Indomethacin; Isoproterenol; Male; Nitrendipine; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thromboxane B2

1993
Sphingosine-1-phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitro.
    British journal of pharmacology, 2000, Volume: 130, Issue:8

    Topics: Animals; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; In Vitro Techniques; Indomethacin; Lysophospholipids; Male; Mesenteric Arteries; Nitrendipine; Nitroarginine; Pertussis Toxin; Phosphorylcholine; Psychosine; Rats; Rats, Wistar; Renal Artery; Sphingosine; Vasoconstriction; Vasodilator Agents; Virulence Factors, Bordetella

2000