nitrendipine has been researched along with felodipine in 199 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 160 (80.40) | 18.7374 |
| 1990's | 15 (7.54) | 18.2507 |
| 2000's | 12 (6.03) | 29.6817 |
| 2010's | 12 (6.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dietel, M; Höllt, V; Kouba, M; Vogt, G | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Beaumont, K; Smith, DA; van De Waterbeemd, H; Walker, DK | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Sun, H | 1 |
| Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Ahlstrøm, F; Bøgeskov-Jensen, I; Frimodt-Møller, J; Lassen, E; Nielsen, MR; Wickers-Nielsen, N; Winkel, O | 1 |
| Danielson, M; Danielsson, BR; Dencker, L; Regård, CG; Reiland, S; Rundqvist, E | 1 |
| Breimer, DD; Roosemalen, MC; Soons, PA | 1 |
| Adkins, E; Emmert, S; Ludden, CT; Ribeiro, LG; Seymour, AA; Sweet, CS | 1 |
| Dalaker, K; Prydz, H | 1 |
| DiBona, GF | 1 |
| Nordlander, M; Thalén, P | 1 |
| Björkman, JA; Drake-Holland, AJ; Hynd, J; Noble, MI; Pettersson, K | 1 |
| Drake-Holland, AJ; Mills, C; Noble, MI; Pugh, S | 3 |
| Julius, S | 1 |
| Elmfeldt, D; Hedner, T; Westerling, S | 1 |
| Bailey, DG; Carruthers, SG | 1 |
| Elmfeldt, D; Hedner, T; Sjögren, E | 1 |
| Kjellstedt, A; Ljung, B; Orebäck, B | 1 |
| Hermsmeyer, K; Rusch, NJ | 1 |
| Cauvin, C; Gelband, C; van Breemen, C | 1 |
| Andrews, CT; Johnson, JD; Khabbaza, EJ; Mills, JS | 1 |
| Berntsson, P; Johansson, E; Westerlund, C | 1 |
| Bohr, DF; Bruner, CA; Furspan, PB; Jokelainen, PT; Luong, VV; Webb, RC | 1 |
| Boström, S; Nilsson, A; Simonsson, R; Westerlund, C | 1 |
| Kjellstedt, A; Ljung, B | 1 |
| Johansson, B; Ljung, B; Nordlander, M | 1 |
| Hökfelt, B; Hulthén, UL; Katzman, PL | 6 |
| Barnes, PC; Bowles, RM; Comerford, MB; Ginks, SE; Ginks, WR; Goves, JR; Grabau, WJ; Hamilton, DV; Malcolm, JP; Rajaratnam, DV | 1 |
| Horton, R; Nordlander, M; Thalén, P | 2 |
| Amery, A; Fagard, R; Hespel, P; Lijnen, P; M'Buyamba-Kabangu, JR; Moerman, E; Staessen, J | 1 |
| Huysmans, FT; Koene, RA; Sluiter, HE; Wetzels, JF | 1 |
| Cubela, R; Debrevi, L; Jackson, B; Johnston, CI; Whitty, M | 1 |
| Bune, A; Chalmers, J; Heath, W; Jackson, B; Johnston, C; Mashford, ML; McGrath, B; West, M; Westwood, B; Wing, L | 1 |
| Marwood, JF | 1 |
| Dahlöf, B; Gudbrandsson, T; Hansson, L; Hellsing, T; Kullman, S; Kuylenstierna, J; Leppert, J; Möller, B; Skogström, K; Svensson, A | 1 |
| Bengtsson-Hasselgren, B; Edgar, B; Rönn, O | 1 |
| Liedholm, H; Melander, A | 1 |
| Dunselman, PH; Edgar, B; Kuntze, CE; Lie, KI; Scaf, AH; van Bruggen, A; Wesseling, H | 1 |
| Andrejak, M; Lesbre, JP; Morand, P; Raveau-Landon, C; Witchitz, S | 1 |
| Chan-Wah-Hak, NS; Jennings, K; Metcalfe, MJ | 1 |
| Dunselman, PH; Hamer, JP; Kuntze, CE; Lie, KI; Scaf, AH; van Bruggen, A; Wessling, H | 1 |
| Aberg, J; Kirch, W; Laskowski, M; Ohnhaus, EE | 1 |
| Abelardo, NS; Mendoza, VL; Mitchell, MJ; Ramos, EF; Sulit, YQ | 1 |
| Bruce, A; Jennings, GL; Sudhir, K | 1 |
| Dunselman, PH; Edgar, B; Kuntze, CE; Scaf, AH; Wesseling, H | 1 |
| Benemio, G; Boldrini, F; Gatteschi, C; Guerrieri, M; Pollavini, G; Porcellati, C; Verdecchia, P | 1 |
| Sutherland, C; Walsh, MP | 1 |
| Attman, PO; Aurell, M; Edgar, B; Herlitz, H; Johnsson, G; Regårdh, CG | 1 |
| Bruner, CA; Webb, RC | 1 |
| Keene, F; Lechner, W; Marth, C; Zech, J | 1 |
| Collste, P; Edgar, B; Kendall, M; Olsson, R; Regårdh, CG; Shansky, C | 1 |
| Billing, B; Bratel, T; Dahlqvist, R | 1 |
| Dunselman, PH; Scaf, AH; Wesseling, H | 1 |
| Bäärnhielm, C; Regårdh, CG; Sutfin, TA; Wang, SX | 1 |
| Alkadhi, KA; Hogan, YH; Jandhyala, BS; Sabouni, MH | 1 |
| Scott-Woo, GC; Sutherland, C; Walsh, MP | 1 |
| Forlani, A; Milani, S; Monopoli, A; Ongini, E | 1 |
| Bratel, T; Hedenstierna, G; Lundquist, H; Nyquist, O; Ripe, E | 1 |
| Jackson, B; Johnston, CI | 1 |
| Amtorp, O; Kassis, E | 1 |
| Anderson, A; Gibson, J; Jackson, B; Morgan, TO | 1 |
| Borgmästars, H; Forsén, B; Hellebø, R; Ibsen, H; Nielsen, E; Nielsen, HM; Steiness, E; Tuomilehto, J; Walle, PO; Winkel, O | 1 |
| Andersson, OK; Granérus, G; Hedner, T | 1 |
| Hedner, T | 1 |
| Bengtsson, B; Edgar, B; Elmfeldt, D; Moberg, L; Rönn, O | 1 |
| Jackson, B; Johnston, CI; McGrath, BP | 1 |
| Sluiter, HE | 1 |
| Capewell, S; Critchley, JA; Freestone, S; Pottage, A; Prescott, LF | 1 |
| Ardissino, D; Barberis, P; Cavallotti, G; De Servi, S; Montemartini, C; Savonitto, S; Specchia, G; Zanini, P | 1 |
| Nordborg, C | 3 |
| O'Donnell, SR; Wanstall, JC | 1 |
| Lamers, JM; Mas-Oliva, J; Verdouw, PD | 1 |
| Carone, MB; Cerasola, G; Cottone, S; D'Ignoto, G; Mangano, MT; Pinto, A | 1 |
| Ellrodt, AG; Langley, MS; Monk, JP; Saltiel, E | 1 |
| Dunselman, PH; Kuntze, CE; Lie, KI; Scaf, AH; Wesseling, H | 1 |
| Barbieri, L; Camerini, F; Mestroni, L | 1 |
| Routledge, PA; Sheridan, DJ; Sheridan, JV; Thomas, P | 1 |
| Bratell, S; Folmerz, P; Hansson, R; Jonsson, O; Lundstam, S; Pettersson, S; Rippe, B; Scherstén, T | 1 |
| Aurell, M; Björck, S; Granérus, G; Herlitz, H; Nyberg, G | 2 |
| Lim, SL; May, PB; Sutter, MC | 1 |
| Boström, SL; Rochester, S; Vogel, HJ; Westerlund, C | 1 |
| Patel, KR; Peers, E | 1 |
| Hutton, I; Martin, W; McGhie, AI; Tweddel, AC | 2 |
| Bailey, DG; Bartle, WR; Edgar, B; Hardy, BG; Myers, M | 1 |
| Ekeroth, M; Ostman, J; Seideman, P | 1 |
| Chow, J | 1 |
| Bohr, DF; Furspan, PB | 1 |
| Aalkjaer, C; Mulvany, MJ; Videbaek, LM | 1 |
| Groom, P; Peers, E; Richardson, PD; Simpson, RJ; Singh, B; Ward, DE | 1 |
| Craig, K; Cumming, AD; Jenkins, DA; Watson, ML | 1 |
| Carle, WK; Latta, D; Lees, CT; Lough, JR; Peers, EM; Pender, J; Richardson, PD; Ross, JR; Sefton, S | 1 |
| Littler, WA; Murray, RG; Tan, LB | 2 |
| Elmfeldt, D; Hedner, T; Sjögren, E; Smith, U; Von Schenck, H | 1 |
| Amtorp, O; Fritz-Hansen, P; Kassis, E; Waldorff, S | 1 |
| Amery, A; Fiocchi, R; Hespel, P; Lijnen, P; Lissens, W; Moerman, E | 1 |
| Burton, RH; Davis, RH; Freeling, P; Goves, JR; Orme-Smith, EA | 1 |
| Muir, AL; Wathen, CG | 1 |
| Elmfeldt, D; Westerling, S | 1 |
| Burton, RH; Davis, RH; Freeling, P; Goves, JR; Graham-Evans, JN; Orne-Smith, EA; Osborne, CJ; Ward, DE | 1 |
| Edgar, B; Lundborg, P; Regårdh, CG | 1 |
| Flygt, G; Krönig, B | 1 |
| Amery, A; De Schaepdryver, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J | 1 |
| Fitzgerald, P; Harrington, K; Hill, KW; O'Brien, E; O'Donnell, P; O'Malley, K | 1 |
| Bune, AJ; Chalmers, JP; Russell, AE; West, MJ; Wing, LM | 1 |
| Ljung, B; Nordlander, M | 1 |
| Sheridan, DJ; Sheridan, JV; Thomas, P | 1 |
| Dunselman, PH; Kuntze, CE; Lie, KI; van Bruggen, A | 1 |
| Katzman, PL | 1 |
| Deierkauf, M; Elferink, JG | 1 |
| O'Regan, MH; Phillis, JW; Walter, GA | 1 |
| Ceschia, G; Pandullo, C; Pivotti, F; Salvi, A; Scardi, S | 1 |
| Ceschia, G; Pandullo, C; Pivotti, F; Pollavini, G; Scardi, S | 1 |
| Hulthén, UL; Katzman, PL | 1 |
| Edgar, B; Gabrielsson, M; Landahl, S; Larsson, M; Lernfelt, B; Lundborg, P; Regårdh, CG | 1 |
| Arner, A; Boström, SL | 1 |
| Hodge, K; Jandhyala, BS; Sabouni, M | 1 |
| Gabrielsson, M; Regårdh, CG; Sutfin, TA | 1 |
| Littler, WA; Mace, PJ; Smith, SA | 2 |
| Dahlöf, C; Elmfeldt, D; Hedner, T; Sjögren, E | 1 |
| Huysman, FT; Koene, RA; Sluiter, HE; Thien, TA | 1 |
| Collste, P; Edgar, B; Haglund, K; Regårdh, CG | 2 |
| Aurell, M; Edgar, B; Johnsson, G; Regårdh, CG; Shansky, C | 1 |
| Billing, E; Lundman, T; Moberg, L; Olsson, G; Rehnqvist, N | 1 |
| Andersson, L; Hoffmann, KJ | 1 |
| Gradnik, R; Leonetti, G; Rupoli, L; Terzoli, L; Zanchetti, A | 1 |
| Amtorp, O; Kassis, E; Waldorff, S | 1 |
| Held, P; Swedberg, K | 1 |
| Friberg, P; Nordlander, M; Wåhlander, H | 1 |
| Hardebo, JE; Kåhrström, J; Nordborg, C | 1 |
| Schmitz, A | 1 |
| Amery, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J | 1 |
| Bush, LR; D'Alonzo, AJ; Evans, RM; Gaul, SL | 1 |
| Ahnoff, M; Ervik, M; Johansson, L | 1 |
| Amery, A; Fagard, R; Staessen, J | 1 |
| Bengtsson, B; Khan, AR; Weiber, R | 1 |
| Askholt, J; Nielsen-Kudsk, F | 1 |
| Bäärnhielm, C; Dahlbäck, H; Skånberg, I | 1 |
| Haraldsson, B; Rippe, B; Zackrisson, U | 1 |
| Maclean, D; Mitchell, ET; Readman, AS | 1 |
| MacLeod, D; Muir, AL; Tucker, L; Wathen, CG | 1 |
| Amery, A; Fiocchi, R; Hespel, P; Lijnen, P; Lissens, W | 1 |
| Jack, DB; Kendall, MJ; Laugher, S; Smith, SR; Wilkins, MR | 1 |
| Adelstein, RS; Movsesian, MA | 1 |
| Ambrose, JM; Dachiw, J; Michalak, RJ; Silver, PJ | 1 |
| Adelstein, RS; Movsesian, MA; Swain, AL | 1 |
| Cross, AJ; Green, AR; Little, HJ; Misra, A; Watson, WP | 1 |
| Arnold, JM; Bailey, DG; Spence, JD | 1 |
| Breimer, DD; Cohen, AF; Soons, PA | 1 |
| Breimer, DD; Cohen, AF; Mulders, TM; Schoemaker, HC; Soons, PA; Uchida, E | 1 |
| Iga, T; Kotaki, H; Nakajima, Y; Sawada, Y; Shimada, S; Yamamoto, K | 1 |
| Kikuchi, K; Sugawara, H; Tobise, K | 1 |
| Little, JJ; Watson, WP | 1 |
| Homewood, N; Little, HJ; Watson, WP | 1 |
| Jaroszkiewicz, E; Marciniec, B; Ogrodowczyk, M; Patterson, LH; Taiwo, FA | 1 |
| Ellsworth, A; Fink, KS | 1 |
| Camargo, C; Núñez-Vergara, LJ; Ortiz, ME; Squella, JA | 1 |
| Hemmateenejad, B; Javidnia, K; Miri, R; Saeidi-Boroujeni, M | 1 |
| Fowler, S; Gray, L; Heikkinen, AT; Li, J; Parrott, N; Peng, Y; Railkar, A; Yadava, P | 1 |
| Ishigai, M; Kato, M; Mitsui, T; Miyake, T; Nagao, S; Nemoto, T; Ogawa, K; Yamada, H | 1 |
8 review(s) available for nitrendipine and felodipine
| Article | Year |
|---|---|
Property-based design: optimization of drug absorption and pharmacokinetics.
Topics: Animals; Biological Transport; Blood Proteins; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane; Drug Design; Eye; Humans; Intestinal Absorption; Models, Biological; Models, Molecular; Nasal Mucosa; Pharmaceutical Preparations; Pharmacokinetics; Prodrugs; Skin Absorption | 2001 |
Felodipine in hypertension--a review.
Topics: Blood Pressure; Drug Tolerance; Felodipine; Heart; Hemodynamics; Humans; Hypertension; Kidney; Nitrendipine; Renin-Angiotensin System | 1987 |
Felodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension.
Topics: Felodipine; Humans; Hypertension; Metabolic Clearance Rate; Nitrendipine | 1988 |
[Calcium antagonists in congestive heart failure].
Topics: Calcium Channel Blockers; Cardiomyopathy, Dilated; Diltiazem; Felodipine; Heart Failure; Hemodynamics; Humans; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Verapamil | 1988 |
Aspects on the benefit-risk balance of felodipine in hypertension.
Topics: Antihypertensive Agents; Felodipine; Humans; Hypertension; Nitrendipine; Risk Factors | 1987 |
Clinical pharmacokinetics of felodipine. A summary.
Topics: Adult; Aged; Antihypertensive Agents; Felodipine; Humans; Intestinal Absorption; Middle Aged; Nitrendipine | 1987 |
Pharmacodynamic properties of felodipine.
Topics: Antihypertensive Agents; Felodipine; Humans; Nitrendipine | 1987 |
Grapefruit juice and drugs. How significant is the interaction?
Topics: Beverages; Biological Availability; Citrus; Dihydropyridines; Drug Interactions; Felodipine; Flavanones; Flavonoids; Half-Life; Humans; Nifedipine; Nitrendipine | 1994 |
60 trial(s) available for nitrendipine and felodipine
| Article | Year |
|---|---|
A comparison of felodipine and nitrendipine in the treatment of hypertension.
Topics: Blood Pressure; Double-Blind Method; Felodipine; Heart Rate; Humans; Hypertension; Nitrendipine; Randomized Controlled Trials as Topic | 1990 |
Tolerance and cardiovascular effects of single dose felodipine/beta-blocker combinations in healthy subjects.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiovascular System; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Drug Tolerance; Felodipine; Heart Rate; Humans; Male; Nitrendipine | 1987 |
Antihypertensive effects and pharmacokinetics of felodipine combined with a beta-blocker and a diuretic.
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Nitrendipine | 1987 |
Catecholamines, renin-angiotensin-aldosterone, and cardiovascular response during exercise following acute and long-term calcium antagonism with felodipine in essential hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Epinephrine; Felodipine; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Norepinephrine; Physical Exertion; Renin-Angiotensin System | 1987 |
Monotherapy with felodipine, a new calcium antagonist, in mild and moderate hypertension.
Topics: Administration, Oral; Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Felodipine; Heart Rate; Humans; Hypertension; Middle Aged; Myocardial Infarction; Nitrendipine; Random Allocation | 1987 |
Effects of felodipine on blood pressure and humoral factors in sodium-replete humans at rest and during exercise.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Felodipine; Heart Rate; Humans; Male; Nitrendipine; Norepinephrine; Physical Exertion; Random Allocation; Renin; Renin-Angiotensin System | 1987 |
The natriuretic effect of the dihydropyridine calcium antagonist felodipine: a placebo-controlled study involving intravenous angiotensin II in normotensive volunteers.
Topics: Adult; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Felodipine; Forearm; Heart Rate; Humans; Infusions, Intravenous; Kidney; Male; Natriuresis; Nitrendipine; Placebos; Vascular Resistance | 1987 |
Felodipine compared to prazosin as additional therapy to a beta-blocking drug.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Prazosin; Pulse; Random Allocation | 1987 |
Antihypertensive effect of felodipine or hydralazine when added to beta-blocker therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nitrendipine; Random Allocation | 1988 |
Dose-dependent effects of felodipine on diuresis and natriuresis in healthy subjects.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diuresis; Dose-Response Relationship, Drug; Felodipine; Heart Rate; Humans; Male; Natriuresis; Nitrendipine; Potassium | 1988 |
A placebo-controlled dose-response study of felodipine extended release in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Body Weight; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Patient Compliance; Random Allocation | 1989 |
Plasma concentration-effect relationship of felodipine intravenously in patients with congestive heart failure.
Topics: Aged; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Double-Blind Method; Felodipine; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Nitrendipine; Random Allocation; Time Factors; Vascular Resistance | 1989 |
[Treatment of essential hypertension with felodipine or atenolol as first line therapy. Comparative double-blind randomized study].
Topics: Adult; Age Factors; Aged; Antihypertensive Agents; Atenolol; Double-Blind Method; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Random Allocation | 1989 |
The effects of treatment with felodipine as a single agent in coronary artery disease.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Exercise; Felodipine; Female; Hemodynamics; Humans; Male; Middle Aged; Nitrendipine; Vasodilator Agents | 1989 |
Efficacy of felodipine in congestive heart failure.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Felodipine; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nitrendipine; Random Allocation; Time Factors | 1989 |
Effects of felodipine on plasma digoxin levels and haemodynamics in patients with heart failure.
Topics: Aged; Calcium Channel Blockers; Clinical Trials as Topic; Digoxin; Felodipine; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nitrendipine; Random Allocation | 1989 |
A comparison of felodipine and nifedipine as monotherapies for the treatment of mild to moderate hypertension.
Topics: Adult; Blood Pressure; Body Weight; Clinical Trials as Topic; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine | 1989 |
Cardiovascular-risk reduction: initial diuretic therapy compared with calcium-antagonist (felodipine) therapy for primary hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Cholesterol; Clinical Trials as Topic; Diuretics; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Norepinephrine; Potassium; Renin; Risk Factors | 1989 |
Pharmacokinetics of felodipine after intravenous and chronic oral administration in patients with congestive heart failure.
Topics: Administration, Oral; Aged; Calcium Channel Blockers; Cardiac Output; Clinical Trials as Topic; Double-Blind Method; Felodipine; Female; Heart Failure; Humans; Injections, Intravenous; Male; Middle Aged; Nitrendipine; Random Allocation | 1989 |
Increased exercise tolerance and reduced electrocardiographic ischaemia 3 and 12 hours after oral felodipine in effort angina.
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Coronary Circulation; Electrocardiography; Exercise Test; Felodipine; Humans; Middle Aged; Nitrendipine; Vasodilator Agents | 1989 |
Cardiovascular and neurohumoral postural responses and baroreceptor abnormalities during a course of adjunctive vasodilator therapy with felodipine for congestive heart failure.
Topics: Aged; Cardiovascular System; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Felodipine; Heart Failure; Hemodynamics; Humans; Middle Aged; Neurotransmitter Agents; Nitrendipine; Norepinephrine; Posture; Pressoreceptors; Random Allocation; Reflex; Time Factors; Vasodilator Agents | 1987 |
Felodipine versus prazosin as an addition to a beta-blocker in the treatment of essential hypertension. The Australian Multicentre Study.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Posture; Prazosin; Random Allocation | 1987 |
Felodipine versus hydrochlorothiazide as an addition to a beta-blocker in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nitrendipine | 1987 |
Felodipine, a new calcium antagonist, as monotherapy in mild or moderate hypertension. Cooperative study group.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Random Allocation; Time Factors | 1987 |
Clinical evaluation of felodipine in hypertensive patients previously treated with a triple drug regimen.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Felodipine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Nitrendipine | 1987 |
A dose-response study of felodipine in patients remaining hypertensive on a beta blocker. Canadian Felodipine Study Group.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Resistance; Felodipine; Female; Humans; Hypertension; Male; Nitrendipine; Random Allocation | 1987 |
Hormonal and blood pressure responses to tilting in beta-blocked essential hypertension treated with felodipine or prazosin.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Prazosin; Pulse; Renin; Vasopressins | 1987 |
Felodipine in hypertensive patients. A dose finding study in patients refractory to beta-blocker monotherapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Random Allocation | 1987 |
Antihypertensive efficacy of the calcium-antagonist felodipine in patients with persisting hypertension on beta-adrenoceptor blocker therapy. The Canadian Felodipine Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Random Allocation | 1988 |
Digoxin-felodipine interaction in patients with congestive heart failure.
Topics: Aged; Clinical Trials as Topic; Digoxin; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Felodipine; Female; Heart Failure; Humans; Male; Middle Aged; Nitrendipine; Prospective Studies | 1988 |
Effects of felodipine on haemodynamics and exercise capacity in patients with angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Exercise Test; Felodipine; Hemodynamics; Humans; Male; Middle Aged; Nitrendipine; Nitroglycerin; Physical Exertion; Random Allocation | 1987 |
Felodipine, a new calcium antagonist, modifies exercise-induced asthma.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Blood Pressure; Calcium Channel Blockers; Felodipine; Female; Forced Expiratory Volume; Heart Rate; Humans; Male; Middle Aged; Nitrendipine | 1988 |
Effect of indomethacin on the pharmacokinetics and pharmacodynamics of felodipine.
Topics: Adult; Blood Pressure; Diuresis; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Felodipine; Heart Rate; Hemodynamics; Humans; Indomethacin; Male; Natriuresis; Nitrendipine; Random Allocation; Time Factors; Vasodilator Agents | 1988 |
Effects of the calcium antagonist felodipine on the sympathetic and renin-angiotensin-aldosterone systems in essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Catecholamines; Clinical Trials as Topic; Double-Blind Method; Felodipine; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Renin-Angiotensin System; Sympathetic Nervous System; Time Factors | 1988 |
A double-blind comparison of felodipine and hydrochlorothiazide added to metoprolol to control hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dizziness; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Headache; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Nitrendipine; Random Allocation; Time Factors | 1988 |
A comparison of felodipine and propranolol as additions to hydrochlorothiazide in the treatment of hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nitrendipine; Propranolol; Random Allocation | 1988 |
Felodipine in patients with chronic heart failure: discrepant haemodynamic and clinical effects.
Topics: Aged; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Echocardiography; Exercise Test; Felodipine; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nitrendipine; Vasodilator Agents | 1987 |
Glucose tolerance in hypertensive patients during treatment with the calcium antagonist, felodipine.
Topics: Blood Glucose; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Felodipine; Glucagon; Glucose Tolerance Test; Humans; Hypertension; Insulin; Kinetics; Male; Middle Aged; Nitrendipine; Norepinephrine; Random Allocation | 1987 |
Efficacy of felodipine in chronic congestive heart failure: a placebo controlled haemodynamic study at rest and during exercise and orthostatic stress.
Topics: Adult; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Felodipine; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nitrendipine; Physical Exertion; Posture; Random Allocation; Stress, Physiological; Supination | 1987 |
Effects of calcium antagonism on the resting and exercise-stimulated renin-aldosterone axis.
Topics: Aldosterone; Blood Pressure; Calcium; Catecholamines; Felodipine; Heart Rate; Humans; Male; Nitrendipine; Physical Exertion; Reference Values; Renin; Renin-Angiotensin System | 1987 |
Control of hypertension in elderly patients with felodipine and metoprolol: a double-blind, placebo-controlled clinical trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Felodipine; Heart Rate; Humans; Hypertension; Metoprolol; Nitrendipine; Random Allocation | 1987 |
The use of felodipine in the treatment of severe hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Felodipine; Female; Humans; Hydralazine; Hypertension; Male; Minoxidil; Nitrendipine; Random Allocation | 1987 |
Hypertension in the elderly. Its diagnosis in general practice and treatment with felodipine and metoprolol.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Felodipine; Heart Rate; Humans; Hypertension; Metoprolol; Nitrendipine; Random Allocation | 1987 |
Felodipine versus Moduretic. A double-blind parallel-group multicentre study.
Topics: Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nitrendipine; Random Allocation | 1987 |
Short and long term treatment of essential hypertension with felodipine as monotherapy.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Time Factors | 1987 |
Felodipine monotherapy in systolic hypertension in the elderly.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Systole | 1987 |
Felodipine in ischaemic heart disease.
Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Felodipine; Female; Hemodynamics; Humans; Male; Middle Aged; Nitrendipine; Random Allocation | 1987 |
Felodipine in heart failure. A double-blind, randomised, placebo-controlled parallel-group study in 23 patients.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Double-Blind Method; Felodipine; Heart Failure; Humans; Nitrendipine; Random Allocation | 1987 |
Acute effects of felodipine in exertional angina pectoris.
Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Exercise Test; Felodipine; Female; Heart Rate; Humans; Male; Middle Aged; Nitrendipine; Physical Exertion; Random Allocation; Time Factors | 1988 |
Comparison of antihypertensive effect and pharmacokinetics of conventional and extended release felodipine tablets in patients with arterial hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Time Factors | 1987 |
Pharmacokinetics of felodipine and effect on digoxin plasma levels in patients with heart failure.
Topics: Aged; Antihypertensive Agents; Digoxin; Felodipine; Female; Heart Failure; Humans; Male; Middle Aged; Nitrendipine | 1987 |
Haemodynamic effects of felodipine during supine resting and exercising states and orthostatic tilt in patients with chronic congestive heart failure.
Topics: Antihypertensive Agents; Chronic Disease; Felodipine; Heart Failure; Hemodynamics; Humans; Nitrendipine; Physical Exertion; Posture | 1987 |
An analytical method to separate inotropic and vasodilatory drug effects in patients with heart failure.
Topics: Aged; Cardiac Output; Cardiotonic Agents; Dobutamine; Felodipine; Female; Heart Failure; Heart Function Tests; Hemodynamics; Humans; Male; Middle Aged; Nitrendipine; Vasodilator Agents | 1987 |
Felodipine, blood pressure, and cardiovascular reflexes in hypertensive humans.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Pressoreceptors; Reflex; Renin; Time Factors | 1986 |
Calcium channel blocker and isosorbide 5-mononitrate in the management of chronic cardiac failure.
Topics: Chronic Disease; Coronary Disease; Drug Therapy, Combination; Exercise Test; Felodipine; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Middle Aged; Nitrendipine | 1987 |
Felodipine as a replacement for minoxidil in the treatment of severe hypertension.
Topics: Aged; Calcium Channel Blockers; Felodipine; Heart Rate; Humans; Hypertension, Malignant; Male; Middle Aged; Minoxidil; Nitrendipine; Random Allocation | 1986 |
Effect of calcium antagonism on intracellular concentrations and transmembrane fluxes of cations in erythrocytes of men at rest and during exercise.
Topics: Adult; Blood Pressure; Calcium; Cations; Erythrocyte Membrane; Erythrocytes; Felodipine; Heart Rate; Humans; Magnesium; Male; Nitrendipine; Physical Exertion; Potassium; Sodium | 1986 |
Pharmacokinetic interactions between felodipine and metoprolol.
Topics: Adult; Double-Blind Method; Drug Interactions; Felodipine; Half-Life; Humans; Kinetics; Male; Metoprolol; Nitrendipine; Time Factors | 1987 |
Comparative effects of felodipine, nitrendipine and nifedipine in healthy subjects: concentration-effect relationships of racemic drugs and enantiomers.
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Felodipine; Heart Rate; Hemodynamics; Humans; Male; Nifedipine; Nitrendipine; Protein Binding; Stereoisomerism | 1993 |
Stereoselective pharmacokinetics of oral felodipine and nitrendipine in healthy subjects: correlation with nifedipine pharmacokinetics.
Topics: Administration, Oral; Adult; Blood Proteins; Double-Blind Method; Felodipine; Half-Life; Humans; Male; Nifedipine; Nitrendipine; Pyridines; Stereoisomerism | 1993 |
131 other study(ies) available for nitrendipine and felodipine
| Article | Year |
|---|---|
Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Biological Transport; Calcium Channel Blockers; Cell Line; Dihydropyridines; Drug Resistance; Haplorhini; Immunoblotting; Membrane Glycoproteins; Mice; RNA, Messenger; Stereoisomerism; Verapamil; Vinblastine | 1992 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction | 2012 |
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Histological and in vitro studies supporting decreased uteroplacental blood flow as explanation for digital defects after administration of vasodilators.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Extremities; Felodipine; Female; In Vitro Techniques; Limb Deformities, Congenital; Maternal-Fetal Exchange; Nifedipine; Nitrendipine; Placenta; Pregnancy; Rabbits; Vasodilator Agents | 1990 |
Enantioselective determination of felodipine and other chiral dihydropyridine calcium entry blockers in human plasma.
Topics: Calcium Channel Blockers; Chromatography, Gas; Chromatography, High Pressure Liquid; Dihydropyridines; Felodipine; Humans; Male; Nitrendipine; Stereoisomerism | 1990 |
Enalapril in experimental hypertension and acute heart failure: comparison with calcium channel blockers.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Dogs; Drug Therapy, Combination; Enalapril; Enalaprilat; Felodipine; Heart; Heart Failure; Hypertension; Lisinopril; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR | 1986 |
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil | 1986 |
Effects of vasodilator antihypertensive agents on renal function.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Felodipine; Hydralazine; Kidney; Kidney Function Tests; Minoxidil; Nitrendipine; Rats; Rats, Inbred SHR; Vasodilator Agents | 1987 |
Emerging concepts in calcium antagonism. With special reference to felodipine. Proceedings of an international workshop. Granada, Spain, February 23-25, 1986.
Topics: Animals; Calcium Channel Blockers; Felodipine; Humans; Nitrendipine | 1987 |
Effects of felodipine on local and neurogenic control of vascular resistance.
Topics: Animals; Cats; Electric Stimulation; Felodipine; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Norepinephrine; Vascular Resistance; Vasomotor System | 1987 |
The positive inotropic effect of felodipine in isovolumically beating dog heart.
Topics: Animals; Cardiotonic Agents; Coronary Vessels; Dogs; Felodipine; Female; Male; Myocardial Contraction; Myocardium; Nitrendipine; Oxygen Consumption; Vasodilation | 1987 |
Does felodipine have a positive inotropic effect in the human?
Topics: Cardiotonic Agents; Felodipine; Humans; Infusions, Intravenous; Myocardial Contraction; Nitrendipine | 1987 |
Discussion on the search for an ideal vasodilator: a hemodynamic perspective.
Topics: Antihypertensive Agents; Felodipine; Hemodynamics; Humans; Hypertension; Nitrendipine; Vascular Resistance; Vasodilation; Vasodilator Agents | 1987 |
Vascular versus myocardial selectivity of calcium antagonists studied by concentration-time-effect relations.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Felodipine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nitrendipine; Papillary Muscles; Rats; Rats, Inbred Strains; Time Factors; Verapamil | 1987 |
Felodipine actions on vascular muscle Ca2+ channels.
Topics: Animals; Calcium; Cells, Cultured; Drug Interactions; Felodipine; Ion Channels; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Rats; Trifluoperazine | 1987 |
45Ca fluxes in rat mesenteric resistance vessels.
Topics: Animals; Arterioles; Biological Transport, Active; Calcium; Felodipine; In Vitro Techniques; Mesenteric Arteries; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 1987 |
The interaction of felodipine with calcium-binding proteins.
Topics: Animals; Binding Sites; Calcium; Calcium-Binding Proteins; Calmodulin; Coronary Vessels; Felodipine; In Vitro Techniques; Ion Channels; Kinetics; Nitrendipine; Troponin; Troponin C; Vasodilation | 1987 |
Felodipine analogs: structure-activity relationships.
Topics: Administration, Oral; Animals; Blood Pressure; Felodipine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nitrendipine; Rats; Rats, Inbred SHR; Structure-Activity Relationship | 1987 |
Antihypertensive action of felodipine in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Felodipine; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitrendipine; Potassium; Rats; Rats, Inbred SHR | 1987 |
Photoaffinity labeling of felodipine-binding proteins in vascular smooth muscle.
Topics: Affinity Labels; Animals; Felodipine; In Vitro Techniques; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Nitrendipine; Photochemistry; Protein Binding; Rats | 1987 |
Functional antagonism of noradrenaline responses by felodipine and other calcium antagonists in vascular smooth muscles.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Felodipine; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Norepinephrine; Portal Vein; Rabbits; Rats; Rats, Inbred Strains | 1987 |
Felodipine sensitivity in vivo and in vitro of activation pathways in vascular smooth muscles.
Topics: Action Potentials; Animals; Cats; Drug Resistance; Felodipine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Norepinephrine; Potassium; Rabbits; Rats; Rats, Inbred Strains; Vascular Resistance | 1987 |
Baroreflex control of heart rate and renin release in SHR following administration of felodipine, an antihypertensive Ca2+ antagonist.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Heart Rate; Hypertension; Metoprolol; Nitrendipine; Pressoreceptors; Rats; Rats, Inbred SHR; Renin | 1987 |
Disparate effects of angiotensin converting enzyme inhibitor and calcium blocker treatment on the preservation of renal structure and function following subtotal nephrectomy or streptozotocin-induced diabetes in the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enalapril; Felodipine; Hypertension; Kidney Failure, Chronic; Nephrectomy; Nitrendipine; Proteinuria; Rats; Rats, Inbred Strains; Verapamil | 1987 |
Studies on the site of the interaction between alpha 1-adrenoceptors and 5-HT2 receptors in rat tail arteries.
Topics: Animals; Arteries; Binding Sites; Diltiazem; Felodipine; In Vitro Techniques; Male; Manganese; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Tail; Verapamil | 1988 |
Activation of protein kinase C by the dihydropyridine calcium channel blocker, felodipine.
Topics: Amino Acids; Blood Platelets; Blood Proteins; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Enzyme Activation; Felodipine; Humans; Nitrendipine; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Kinase C | 1989 |
Pharmacokinetics of felodipine in patients with impaired renal function.
Topics: Administration, Oral; Adult; Blood Pressure; Calcium Channel Blockers; Felodipine; Half-Life; Heart Rate; Humans; Hypertension, Renal; Injections, Intravenous; Male; Middle Aged; Nitrendipine | 1989 |
Effect of felodipine on blood pressure and vascular reactivity in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Felodipine; Hypertension; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Norepinephrine; Rats; Rats, Inbred SHR | 1989 |
[Felodipine and circulatory disturbances].
Topics: Blood Circulation; Felodipine; Humans; Nitrendipine | 1989 |
Calcium and calmodulin antagonism for inhibition of uterine contractions.
Topics: Calcium; Calmodulin; Culture Techniques; Diltiazem; Felodipine; Female; Humans; Nitrendipine; Pregnancy; Uterine Contraction | 1989 |
Pharmacokinetics of felodipine in patients with liver disease.
Topics: Adult; Aged; Aging; Blood Pressure; Calcium Channel Blockers; Felodipine; Female; Heart Rate; Humans; Intestinal Absorption; Liver Diseases; Male; Middle Aged; Models, Biological; Nitrendipine; Protein Binding | 1989 |
Felodipine reduces the absorption of theophylline in man.
Topics: Adult; Blood Pressure; Caffeine; Calcium Channel Blockers; Drug Interactions; Felodipine; Humans; Intestinal Absorption; Male; Nitrendipine; Theophylline | 1989 |
Oral pharmacokinetics of felodipine in patients with congestive heart failure: variable prediction using intravenous data.
Topics: Administration, Oral; Aged; Calcium Channel Blockers; Double-Blind Method; Felodipine; Female; Heart Failure; Humans; Injections, Intravenous; Male; Middle Aged; Nitrendipine; Predictive Value of Tests; Random Allocation | 1989 |
Contribution of the intestine to the first-pass metabolism of felodipine in the rat.
Topics: Animals; Biological Availability; Calcium Channel Blockers; Felodipine; Intestinal Mucosa; Male; Metabolic Clearance Rate; Nitrendipine; Portal System; Rats; Rats, Inbred Strains | 1989 |
Effects of felodipine and verapamil on transmission in the isolated superior cervical ganglion of the rat.
Topics: Action Potentials; Animals; Autonomic Nervous System; Calcium Channel Blockers; Felodipine; Ganglia, Spinal; Hexamethonium Compounds; In Vitro Techniques; Nitrendipine; Rats; Synaptic Transmission; Verapamil | 1987 |
Effects of felodipine (a dihydropyridine calcium channel blocker) and analogues on calmodulin-dependent enzymes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Actins; Animals; Ca(2+) Mg(2+)-ATPase; Calcium Channel Blockers; Calmodulin; Calmodulin-Binding Proteins; Chickens; Cyclic Nucleotide Phosphodiesterases, Type 1; Electrophoresis, Polyacrylamide Gel; Felodipine; Muscle, Smooth; Myosin-Light-Chain Kinase; Myosins; Nitrendipine; Phosphorylation; Protein Kinase Inhibitors | 1988 |
Antihypertensive effect of spirapril and felodipine during repeated administration to spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enalapril; Felodipine; Heart Rate; Male; Nitrendipine; Random Allocation; Rats; Rats, Inbred SHR; Vasodilator Agents | 1988 |
Cardiac function and central haemodynamics in severe chronic obstructive lung disease. Acute and long-term effects of felodipine.
Topics: Aged; Cardiac Output; Felodipine; Female; Heart; Hemodynamics; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Nitrendipine; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Time Factors | 1988 |
The contribution of systemic hypertension to progression of chronic renal failure in the rat remnant kidney: effect of treatment with an angiotensin converting enzyme inhibitor or a calcium inhibitor.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Enalapril; Felodipine; Female; Hypertension, Renovascular; Kidney Failure, Chronic; Nitrendipine; Rats; Rats, Inbred Strains | 1988 |
Felodipine in combination with a beta-blocker and a diuretic in chronic treatment of patients with refractory primary hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combination; Felodipine; Heart Rate; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nitrendipine; Renal Circulation | 1987 |
Pharmacokinetics and haemodynamics of felodipine in hypertensive patients treated concomitantly with a beta-blocker.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Drug Therapy, Combination; Felodipine; Half-Life; Hemodynamics; Humans; Hypertension; Middle Aged; Nitrendipine | 1987 |
The effects of felodipine on left ventricular function in beta-blocked patients.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Interactions; Felodipine; Heart; Humans; Myocardial Contraction; Nitrendipine; Stimulation, Chemical; Vasodilation | 1987 |
Reduced felodipine bioavailability in patients taking anticonvulsants.
Topics: Administration, Oral; Adult; Anticonvulsants; Antipyrine; Biological Availability; Drug Administration Schedule; Drug Evaluation; Epilepsy; Felodipine; Female; gamma-Glutamyltransferase; Half-Life; Humans; Male; Microsomes, Liver; Nitrendipine | 1988 |
Effect of felodipine on hyperventilation-induced ischemic attacks in variant angina pectoris.
Topics: Aged; Angina Pectoris, Variant; Blood Pressure; Calcium Channel Blockers; Coronary Vasospasm; Double-Blind Method; Felodipine; Heart Rate; Humans; Hyperventilation; Male; Middle Aged; Nitrendipine; Random Allocation | 1989 |
The influence of antihypertensive treatment on the mesenteric arterial structure in spontaneously hypertensive rats. A morphometric study.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Heart Rate; Male; Mesenteric Arteries; Metoprolol; Muscle, Smooth, Vascular; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1989 |
Influence of age on calcium entry blocking drugs in rat aorta is spasmogen-dependent.
Topics: Aging; Animals; Aorta; Calcium; Calcium Channel Blockers; Diltiazem; Drug Interactions; Felodipine; Male; Nitrendipine; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Serotonin | 1989 |
The effects of felodipine and bepridil on calcium-stimulated calmodulin binding and calcium pumping ATPase of cardiac sarcolemma before and after removal of endogenous calmodulin.
Topics: Animals; Bepridil; Calcium; Calcium-Transporting ATPases; Calmodulin; Felodipine; Imidazoles; In Vitro Techniques; Myocardium; Nitrendipine; Pyrrolidines; Sarcolemma | 1987 |
Effects of felodipine on natriuresis, atrial natriuretic factor, the renin-angiotensin-aldosterone system, and blood pressure in essential hypertension.
Topics: Adult; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Natriuresis; Nitrendipine; Renal Circulation; Renin-Angiotensin System | 1988 |
Effects of oxygen free radical scavengers, xanthine oxidase inhibition and calcium entry-blockers on leakage of albumin after ischaemia. An experimental study in rabbit kidneys.
Topics: Allopurinol; Animals; Calcium Channel Blockers; Capillary Permeability; Catalase; Felodipine; Free Radicals; Ischemia; Kidney; Mannitol; Nifedipine; Nitrendipine; Oxygen; Rabbits; Serum Albumin, Radio-Iodinated; Superoxide Dismutase; Xanthine Oxidase | 1988 |
Effects of felodipine in patients with refractory hypertension and progressive renal disease.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Felodipine; Female; Glomerular Filtration Rate; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Middle Aged; Nitrendipine | 1988 |
Manganese can inhibit or potentiate contractile responses in mesenteric portal vein.
Topics: Animals; Barium; Calcium; Felodipine; Gallopamil; In Vitro Techniques; Male; Manganese; Mesenteric Veins; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Spectrophotometry, Atomic; Strontium; Tissue Distribution; Verapamil | 1988 |
Binding of a dihydropyridine felodipine-analogue to calmodulin and related calcium-binding proteins.
Topics: Binding, Competitive; Calcium Channel Blockers; Calcium-Binding Proteins; Calmodulin; Chromatography, Affinity; Felodipine; Nitrendipine; Peptide Fragments; Structure-Activity Relationship; Troponin; Troponin C | 1988 |
Sustained haemodynamic effects of felodipine in patients with chronic cardiac failure.
Topics: Adult; Blood Pressure; Exercise; Felodipine; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nitrendipine; Vascular Resistance; Vasodilator Agents | 1988 |
Effect of felodipine in refractory hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine | 1988 |
The effects of combining felodipine and metoprolol in moderate to severe hypertension--a one year study.
Topics: Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nitrendipine | 1988 |
Effects of felodipine on blood pressure and lymphocyte membrane characteristics in spontaneously hypertensive stroke-prone rats.
Topics: Animals; Blood Pressure; Calcium; Cell Membrane; Felodipine; Female; In Vitro Techniques; Lymphocytes; Male; Nitrendipine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1988 |
Vasodilatation with pinacidil. Mode of action in rat resistance vessels.
Topics: Animals; Blood Vessels; Felodipine; Guanidines; In Vitro Techniques; Male; Membrane Potentials; Muscle Denervation; Muscle, Smooth, Vascular; Nitrendipine; Pinacidil; Potassium; Potassium Radioisotopes; Rats; Rats, Inbred WKY; Rubidium; Rubidium Radioisotopes; Splanchnic Circulation; Vascular Resistance; Vasodilator Agents | 1988 |
The acute renal haemodynamic and endocrine response to felodipine in normal man.
Topics: Adult; Diuresis; Felodipine; Humans; Kallikreins; Male; Natriuresis; Nitrendipine; Prostaglandins; Renal Circulation; Renin; Vasodilator Agents | 1988 |
Unchanged insulin secretion and glucose tolerance but increased insulin clearance during long-term calcium antagonism with felodipine in essential hypertension.
Topics: Adult; Blood Glucose; C-Peptide; Calcium Channel Blockers; Felodipine; Homeostasis; Humans; Hypertension; Insulin; Insulin Secretion; Lipids; Male; Middle Aged; Nitrendipine | 1987 |
Glucoregulatory hormone response to insulin-induced hypoglycaemia following long-term calcium antagonism with felodipine in patients with essential hypertension.
Topics: Adult; Blood Glucose; Calcium Channel Blockers; Epinephrine; Felodipine; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypertension; Insulin; Male; Middle Aged; Nitrendipine; Norepinephrine; Thyrotropin; Thyroxine; Triiodothyronine | 1987 |
Effects of felodipine and metoprolol on blood pressure, plasma renin, angiotensin II, aldosterone and catecholamines in hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Electrocardiography; Felodipine; Humans; Hypertension; Male; Metoprolol; Nitrendipine; Renin; Time Factors | 1987 |
Baroreflex control of renin release in spontaneously hypertensive rats after administration of felodipine.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Hypertension; Male; Nitrendipine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex; Renin | 1987 |
Glucose tolerance and secretion and clearance of insulin during long term felodipine treatment.
Topics: Adult; Antihypertensive Agents; C-Peptide; Felodipine; Glucagon; Glucose Tolerance Test; Humans; Hypertension; Insulin; Insulin Secretion; Male; Middle Aged; Nitrendipine | 1987 |
Calcium antagonism with felodipine in essential hypertension. Effects on cardiovascular and renal function, the sympathetic and the renin-angiotensin-aldosterone systems, glucose tolerance and glucoregulatory hormones.
Topics: Adult; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Exercise Test; Felodipine; Glucagon; Heart Rate; Humans; Hypertension; Insulin; Kidney; Middle Aged; Nitrendipine; Renin-Angiotensin System; Sympathetic Nervous System | 1987 |
Felodipine-induced inhibition of polymorphonuclear leukocyte functions.
Topics: Animals; Calcium; Calcium Channel Blockers; Chemotaxis, Leukocyte; Erythrocytes; Exocytosis; Felodipine; Humans; Kinetics; L-Lactate Dehydrogenase; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrendipine; Nitroblue Tetrazolium; Prenylamine; Rabbits | 1988 |
Effects of nifedipine and felodipine on adenosine and inosine release from the hypoxemic rat cerebral cortex.
Topics: Adenosine; Animals; Cerebral Cortex; Felodipine; Hypoxia, Brain; Inosine; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1988 |
Influence of antihypertensive treatment on basal cerebral arteries in spontaneously hypertensive rats. A morphometric study.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cerebral Arteries; Drug Therapy, Combination; Felodipine; Heart Rate; Hypertension; Metoprolol; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1988 |
Exercise-induced intermittent angina and ST-segment elevation in Prinzmetal's angina.
Topics: Angina Pectoris, Variant; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Diltiazem; Electrocardiography; Exercise Test; Felodipine; Heart Conduction System; Humans; Male; Middle Aged; Nitrendipine | 1988 |
Renal effects of acute and long-term treatment with felodipine in essential hypertension.
Topics: Adult; Felodipine; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Nitrendipine; Renal Circulation; Sodium; Time Factors; Vasodilation | 1988 |
Pharmacokinetics and blood pressure effects of felodipine in elderly hypertensive patients. A comparison with young healthy subjects.
Topics: Adult; Age Factors; Aged; Blood Pressure; Felodipine; Female; Humans; Hypertension; Kidney; Liver; Liver Circulation; Male; Nitrendipine | 1988 |
Effects of felodipine on energy turnover in the rat portal vein.
Topics: Adenine Nucleotides; Animals; Energy Metabolism; Felodipine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Oxygen Consumption; Phosphocreatine; Portal Vein; Rats; Rats, Inbred Strains | 1988 |
Restoration of renal and mesenteric hemodynamics by felodipine in a canine model of hemorrhagic shock.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Felodipine; Hemodynamics; Nitrendipine; Renal Circulation; Shock, Hemorrhagic; Splanchnic Circulation; Vascular Resistance | 1988 |
Effects of biliary excretion on the disposition of felodipine and metabolites in the rat.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Felodipine; Male; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains | 1987 |
Second International Meeting on Felodipine. Proceedings of a symposium. Frankfurt, 30-31 August 1986.
Topics: Animals; Antihypertensive Agents; Felodipine; Humans; Nitrendipine | 1987 |
Felodipine monotherapy in hypertension.
Topics: Antihypertensive Agents; Felodipine; Humans; Hypertension; Nitrendipine | 1987 |
Clinical evaluation of felodipine in patients with refractory hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Drug Resistance; Felodipine; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine | 1987 |
Antihypertensive and biochemical effects of the dihydropyridine felodipine in the long term treatment of moderate to severe hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine | 1987 |
Pharmacokinetics and haemodynamics of felodipine as monotherapy in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Felodipine; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nitrendipine | 1987 |
Effects of impaired renal function on the pharmacokinetics of felodipine.
Topics: Adult; Antihypertensive Agents; Felodipine; Humans; Kidney Diseases; Male; Middle Aged; Nitrendipine | 1987 |
Metabolism of [14C] felodipine, a new vasodilating drug, in healthy volunteers.
Topics: Biotransformation; Chromatography, Liquid; Felodipine; Half-Life; Humans; Nitrendipine; Vasodilator Agents | 1987 |
Renal effects of felodipine in hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Diuresis; Felodipine; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Natriuresis; Nitrendipine; Posture; Sodium; Water-Electrolyte Balance | 1987 |
Effect of long term felodipine treatment on renal vascular tone, glomerular filtration rate and renal tubular function in essential hypertension.
Topics: Antihypertensive Agents; Felodipine; Glomerular Filtration Rate; Humans; Hypertension; Kidney Tubules; Male; Muscle Tonus; Muscle, Smooth, Vascular; Nitrendipine | 1987 |
Haemodynamic effects of felodipine in congestive heart failure.
Topics: Adult; Aged; Antihypertensive Agents; Felodipine; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Nitrendipine; Physical Exertion | 1987 |
Problem of measuring the positive inotropic property of a vasodilating drug: an illustration using felodipine.
Topics: Adult; Aged; Cardiotonic Agents; Coronary Disease; Felodipine; Female; Heart Function Tests; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Nitrendipine; Vasodilator Agents | 1987 |
Structural and functional adaptations within the myocardium and coronary vessels after antihypertensive therapy in spontaneously hypertensive rats.
Topics: Animals; Coronary Circulation; Coronary Vessels; Felodipine; Hypertension; Metoprolol; Myocardium; Nitrendipine; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Vascular Resistance | 1986 |
Does sympathectomy or antihypertensive treatment affect the morphometry of basal cerebral arteries in spontaneously hypertensive rats?
Topics: Age Factors; Animals; Blood Pressure; Cerebral Arteries; Felodipine; Ganglia, Sympathetic; Hypertension; Metoprolol; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathectomy | 1986 |
Acute renal effects of oral felodipine in normal man.
Topics: Adult; Blood Pressure; Felodipine; Glomerular Filtration Rate; Heart Rate; Humans; Kidney; Kidney Function Tests; Male; Nitrendipine; Renal Circulation; Vascular Resistance | 1987 |
Acute haemodynamic and humoral responses to felodipine and metoprolol in mild hypertension.
Topics: Adult; Aldosterone; Antihypertensive Agents; Calcium Channel Blockers; Catecholamines; Drug Therapy, Combination; Felodipine; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Nitrendipine; Pulmonary Circulation; Renin-Angiotensin System; Vasodilator Agents | 1987 |
Comparative effects of verapamil, diltiazem and felodipine during experimental digitalis-induced arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Dogs; Felodipine; Female; Male; Nitrendipine; Ouabain; Verapamil | 1987 |
Comparison of high-selectivity gas chromatographic methods, including column switching, for the determination of felodipine in plasma.
Topics: Chromatography, Gas; Electrochemistry; Felodipine; Gas Chromatography-Mass Spectrometry; Humans; Nitrendipine | 1987 |
The use of Doppler echocardiography to assess the acute haemodynamic response to felodipine and metoprolol in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Cardiac Output; Echocardiography; Felodipine; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Nitrendipine; Stroke Volume; Vascular Resistance | 1987 |
Low potency of Ca antagonists in smooth muscle from different levels of the respiratory tract.
Topics: Animals; Bronchi; Calcium Channel Blockers; Felodipine; Female; Gallopamil; Guinea Pigs; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Respiratory Muscles; Trachea; Verapamil | 1987 |
The influence of antihypertensive treatment on the renal arterial structure in spontaneously hypertensive rats. A morphometric study.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Heart Rate; Hypertension; Male; Metoprolol; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery | 1987 |
Pharmacokinetics and haemodynamic effects of felodipine as monotherapy in hypertensive patients.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Felodipine; Heart Rate; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Nitrendipine | 1987 |
Felodipine, pharmacodynamics and pharmacokinetics in the isolated rabbit heart.
Topics: Animals; Electrocardiography; Felodipine; Female; Heart; Heart Rate; In Vitro Techniques; Kinetics; Male; Myocardial Contraction; Nitrendipine; Oxygen Consumption; Rabbits; Vasodilation | 1986 |
In vivo pharmacokinetics of felodipine predicted from in vitro studies in rat, dog and man.
Topics: Animals; Cytochrome P-450 Enzyme System; Dogs; Felodipine; Female; Humans; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Nitrendipine; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
Calcium dependence of histamine-induced increases in capillary permeability in isolated perfused rat hindquarters.
Topics: Animals; Calcium; Capillary Permeability; Capillary Resistance; Felodipine; Hindlimb; Histamine; Magnesium; Male; Nitrendipine; Perfusion; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Felodipine compared to nifedipine as "third-line drug" in resistant hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Drug Evaluation; Drug Resistance; Felodipine; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Time Factors | 1986 |
Inhibition of turkey gizzard myosin light chain kinase activity by BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calmodulin; Enzyme Activation; Felodipine; Gizzard, Avian; In Vitro Techniques; Myosin-Light-Chain Kinase; Nifedipine; Nitrendipine; Protein Kinase Inhibitors; Turkeys | 1984 |
Effects of felodipine, nitrendipine and W-7 on arterial myosin phosphorylation, actin-myosin interactions and contraction.
Topics: Actins; Actomyosin; Animals; Calmodulin; Cattle; Contractile Proteins; Felodipine; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardium; Myosins; Nifedipine; Nitrendipine; Phosphorylation; Protein Binding; Rabbits; Sulfonamides; Vasoconstriction | 1984 |
Inhibition of turkey gizzard myosin light chain. Kinase activity by dihydropyridine calcium antagonists.
Topics: Animals; Calcium; Calcium Channel Blockers; Felodipine; Gizzard, Avian; Kinetics; Myosin-Light-Chain Kinase; Myosins; Nifedipine; Nitrendipine; Phosphorylation; Protein Kinase Inhibitors; Trypsin; Turkeys | 1984 |
The differential effects of felodipine and nitrendipine on cerebral dihydropyridine binding ex vivo and the ethanol withdrawal syndrome in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bicuculline; Binding Sites; Brain; Ethanol; Felodipine; Isradipine; Male; Mice; Nitrendipine; Substance Withdrawal Syndrome | 1994 |
In vitro-in vivo correlation of pharmacodynamics of felodipine in essential hypertensive patients based on an ion-channel binding model.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Felodipine; Humans; Hypertension; Male; Nitrendipine; Rats; Rats, Wistar | 1996 |
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Felodipine; Fumarates; Heart; Iron; Lipid Peroxidation; Male; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Verapamil | 1996 |
Effects of dihydropyridines on the components of the ethanol withdrawal syndrome: possible evidence for involvement of potassium, as well as calcium?
Topics: Alcohol Withdrawal Delirium; Aminophylline; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Electroencephalography; Felodipine; Handling, Psychological; Male; Mice; Mice, Inbred Strains; Neurologic Examination; Nitrendipine; Phosphodiesterase Inhibitors; Potassium; Potassium Channels | 1997 |
Differing acute interactions of ethanol with two structurally related dihydropyridines, nitrendipine and felodipine.
Topics: Anesthesia, General; Animals; Ataxia; Calcium Channel Blockers; Drug Interactions; Ethanol; Felodipine; Male; Mice; Motor Activity; Nitrendipine; Structure-Activity Relationship | 1998 |
Free radicals in irradiated drugs: an EPR study.
Topics: Calcium Channel Blockers; Dose-Response Relationship, Radiation; Electron Spin Resonance Spectroscopy; Felodipine; Free Radicals; Gamma Rays; Nifedipine; Nimodipine; Nitrendipine | 1999 |
Antihypertensive treatment and CHD in the elderly.
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Complications; Double-Blind Method; Felodipine; Fosinopril; Humans; Hypertension; Myocardial Infarction; Nisoldipine; Nitrendipine; Randomized Controlled Trials as Topic | 1999 |
Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide.
Topics: Calcium Channel Blockers; Felodipine; Nifedipine; Nimodipine; Nitrendipine; Superoxides | 2004 |
Application of a self-modeling curve resolution method for studying the photodegradation kinetics of nitrendipine and felodipine.
Topics: Calcium Channel Blockers; Drug Stability; Felodipine; Kinetics; Nitrendipine; Photolysis | 2008 |
In vitro to in vivo extrapolation and physiologically based modeling of cytochrome P450 mediated metabolism in beagle dog gut wall and liver.
Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dogs; Domperidone; Felodipine; Humans; In Vitro Techniques; Intestines; Kinetics; Liver; Nitrendipine; Permeability; Piperazines; Purines; Quinidine; Sildenafil Citrate; Sulfones; Tissue Distribution | 2013 |
A useful model capable of predicting the clearance of cytochrome 3A4 (CYP3A4) substrates in humans: validity of CYP3A4 transgenic mice lacking their own Cyp3a enzymes.
Topics: Alprazolam; Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Felodipine; Humans; Male; Mice; Mice, Transgenic; Microsomes, Liver; Midazolam; Nifedipine; Nitrendipine; Quinidine | 2014 |