nitrendipine has been researched along with dihydropyridines in 175 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (36.00) | 18.7374 |
| 1990's | 93 (53.14) | 18.2507 |
| 2000's | 14 (8.00) | 29.6817 |
| 2010's | 5 (2.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haruno, A; Kanda, A; Miyake, H; Nagasaka, M | 1 |
| Reider, N; Zernig, G | 1 |
| Blanck, TJ; Fiskum, G; Hoehner, PJ; Rosenthal, RE; Roy, R | 1 |
| Böck, G; Drach, J; Grunicke, H; Hofmann, J; Ludescher, C; Spitaler, M; Wolf, A | 1 |
| Hallaq, H; Leaf, A; Smith, TW | 1 |
| Baumgarten, LB; Toscas, K; Villereal, ML | 1 |
| Babcock, DF; Corron, ME; Florman, HM; Kim, TD | 1 |
| Dohmoto, H; Hashiguchi, Y; Hayashi, Y; Hosono, M; Iida, H; Ikeda, K; Watanabe, N; Yamamoto, H; Yoshimoto, R | 1 |
| Fricke, U; Klaus, W; Kojda, G; Werner, G | 1 |
| Mason, RP; Moisey, DM; Shajenko, L | 1 |
| Gual, A; López, A; Palacios-Araus, L; Palés, J | 1 |
| Bladen, C; Dunn, SM | 1 |
| Andersen, N; Gougoutas, J; Hedberg, A; Kimball, SD; Malley, M; Moreland, S; Porubcan, M; Pudzianowski, A; Rovnyak, G | 1 |
| Chou, MY; Shibuya, T; Watanabe, Y | 1 |
| Kasuya, Y; Masuda, Y; Sakai, T; Tanaka, S; Yamashita, T | 1 |
| Battaini, F; Bergamaschi, S; Govoni, S; Meucci, O; Parenti, M; Schettini, G; Trabucchi, M | 1 |
| Carpi, C; Collodel, A; Gaviraghi, G; Micheli, D; Semeraro, C | 1 |
| Bolger, GT; O'Neill, SK; Triggle, CR | 1 |
| Fox, AP; Hirning, LD; Miller, RJ | 1 |
| Regan, LJ | 1 |
| de Pascual, R; Gandía, L; García, AG; López, MG; Michelena, P | 1 |
| Gambini, F; Gaviraghi, G; Micheli, D; Quartaroli, M; Tarter, G; Trist, DG | 1 |
| Aihara, H; Kaneko, K; Tsuchida, K | 1 |
| Fujimoto, M; Mihara, S | 1 |
| Butterworth, AR; Dolin, SJ; Little, HJ; Patch, TL; Siarey, RJ; Whittington, MA | 1 |
| Hofmann, F; Meyer, HE; Nastainczyk, W; Regulla, S; Schneider, T | 1 |
| Bean, BP; Regan, LJ; Sah, DW | 1 |
| Asano, M; Fujikura, T; Inagaki, O; Matsumoto, Y; Shibasaki, K; Takenaka, T; Terai, M; Uchida, W | 1 |
| Bettelini, L; Ceserani, R; Corsi, M; Crema, A; D'Angelo, L; De Ponti, F; Toson, G | 1 |
| Rampe, D; Schilling, WP; Zaher, MC | 1 |
| Murphy, BJ; Tuana, BS; Washkurak, AW | 1 |
| Brennan, CH; Crabbe, J; Littleton, JM | 1 |
| Antkiewicz-Michaluk, L; Michaluk, J; Romańska, I; Vetulani, J | 1 |
| Kurosawa, H; Nagasaki, M; Naito, K; Tamaki, H | 1 |
| de Casa-Juana, MF; Gómez, MM; González-Morales, MA; Ortega, MP; Priego, JG; Santos, L; Sunkel, CE; Villarroya, M | 1 |
| Gordon, T; Howlett, SE | 1 |
| Archibald, JL; Bradley, G; Ennis, C; Opalko, A; Shepperson, NB; Ward, TJ; White, JC | 1 |
| Atwal, KS; Floyd, DM; Gougoutas, JZ; Hedberg, A; Malley, MF; Moreland, S; Rovnyak, GC; Schwartz, J | 1 |
| Breimer, DD; Roosemalen, MC; Soons, PA | 1 |
| Hosey, MM; McMahon, KK; Ptasienski, J | 1 |
| Carpenter, CL; Cooper, EC; Greenberg, DA | 2 |
| Lee, HR; Roeske, WR; Watson, M; Yamamura, HI | 1 |
| Brown, AM; Dumont, L; Grupp, G; Grupp, IL; Hamilton, S; Schwartz, A; Vaghy, PL; Williams, JS; Yatani, A | 1 |
| Litzinger, MJ; Nelson, PG; Pun, RY | 1 |
| Kongsamut, S; Miller, RJ | 1 |
| Bean, BP; Hermsmeyer, K; Puga, A; Sturek, M | 1 |
| Chernow, B; Ives, N; King, JW; Roth, BL | 1 |
| Baldwin, JJ; Claremon, DA; Faison, EP; Kaczorowski, GJ; Lumma, PK; McClure, DE; Rosenthal, SA; Smith, GM; Trumble, MJ; Winquist, RJ | 1 |
| Brown, AM; Brush, K; Hamilton, SL; Schwartz, A; Yatani, A | 1 |
| Brennan, CH; Charles, S; Hudspith, MJ; Littleton, JM | 1 |
| Berg, C; DiFrancesco, GF; Gittos, M; Mir, AK; Petty, MA; Spedding, M | 1 |
| Challoner-Hue, L; Steele, TH | 1 |
| Bacher, J; Bolger, GT; Isaac, L; Weissman, BA | 1 |
| Harper, JC; Littleton, JM; Pagonis, C | 1 |
| Oswald, RE; Simasko, SM; Weiland, GA | 1 |
| Askanas, V; Desnuelle, C; Engel, WK | 1 |
| Clementi, F; Pandiella, A; Sher, E | 1 |
| Massieu, L; Tapia, R | 1 |
| Dunn, SM | 2 |
| Bihoreau, C; Clauser, H; Drouva, SV; Kordon, C; Laplante, E; Rasolonjanahary, R; Rerat, E | 1 |
| Cortese, C; Ferrara, LA; Gnasso, A; Mancini, M; Marotta, T; Pasanisi, F | 1 |
| Hawthorn, M; Triggle, DJ; Zheng, W | 1 |
| Ennis, C; Granger, SE; Middlefell, VC; Philpot, ME; Shepperson, NB | 1 |
| Fujisue, T; Ichida, S; Masada, A; Matsuda, N; Yoshioka, T | 1 |
| Holland, DR; Kauffman, RF; Smallwood, JK; Steinberg, MI; Turk, JA; Utterback, BG; Wikel, JH; Zimmerman, KM | 1 |
| Dodd, PR; Gundlach, AL; Harper, CG; Johnston, GA; Kril, JJ | 1 |
| Ehrhardt, JD; Quennedey, MC; Rouot, B; Schwartz, J; Welsch, M | 1 |
| Chartrand, C; Dumont, L; Kangha, M; Lord, C | 1 |
| Decker, N; Delgado, A; Leclerc, G; Marciniak, G; Schwartz, J; Velly, J | 1 |
| Goldin, SM; Turner, TJ | 1 |
| Freedman, SB; Kongsamut, S; Miller, RJ | 1 |
| Ishii, A | 1 |
| Amoroso, S; Annunziato, L; Canzoniero, LM; Di Renzo, GF; Fatatis, A; Taglialatela, M | 1 |
| Aihara, H; Muramatsu, M; Tanaka, M | 1 |
| Hanbauer, I; Sanna, E | 2 |
| Kostiuk, PG; Rozhmanova, OM; Soldatov, NM; Stel'makh, LN; Voronina, SG | 1 |
| Glossmann, H; Graziadei, I; Moshammer, T; Zernig, G | 1 |
| Knaus, EE; Li-Kwong-Ken, MC; Soboleski, DA; Triggle, CR; Wolowyk, MW; Wynn, H | 1 |
| Bolger, GT; Rafferty, MF; Skolnick, P | 1 |
| Burnett, JC; Ritter, SG; Strong, CG; Zachariah, PK | 1 |
| Schilling, WP | 1 |
| Barrett, JE; Bolger, GT; Lueddens, H; Paul, SM; Skolnick, P; Weissman, BA; Witkin, J | 1 |
| Campbell, KP; Kahl, SD; Sharp, A; Strom, M | 1 |
| Fairhurst, AS; Minaskanian, G; Pham, DH; Schultz, CM; Thayer, SA | 1 |
| Miller, RJ; Murphy, SN; Shangold, GA | 1 |
| Bowling, N; Conery, BG; Hayes, JS; Kauffman, RF | 1 |
| Brandt, NR; Caswell, AH; Kawamoto, RM | 1 |
| Cillero, FJ; Fau de Casa-Juana, M; Ortega, MP; Priego, JG; Sunkel, CE | 1 |
| Pugsley, TA; Quade, MM; Shih, YH; Taylor, DG; Weishaar, RE | 1 |
| Katz, AM; Leach, NM | 1 |
| Glossmann, H; Zernig, G | 1 |
| Gengo, P; Su, CM; Triggle, DJ; Yousif, FB | 1 |
| Giacomini, JC; Giacomini, KM; Nelson, WL; Zobrist, RH | 1 |
| Kass, RS; Sanguinetti, MC | 1 |
| Jones, H; Khandwala, A; Van Inwegen, RG; Weinryb, I | 1 |
| Bolger, G; Fraser, CM; Jung, CY; Schaber, JS; Triggle, DJ; Venter, JC | 1 |
| Freedman, SB; Miller, RJ | 1 |
| Altura, BM; Altura, BT | 1 |
| Luu, MD; Martin, JV; Mendelson, WB; Paul, SM; Skolnic, P; Wagner, R | 1 |
| Morales Mulia, M; Morán, J; Pasantes-Morales, H; Sánchez-Olea, R | 1 |
| Artalejo, CR; Cillero, FJ; de Casa-Juana, MF; de Pascual, R; García, AG; González-Morales, MA; López, MG; Priego, J; Sunkel, C; Villarroya, M | 1 |
| Gomis, A; Gutierrez, LM; Reig, JA; Sala, F; Viniegra, S | 1 |
| Bogdanov, K; Hallaq, H; Lakatta, E; Leaf, A; Pepe, S; Spurgeon, H | 1 |
| Drímal, J | 1 |
| Cox, TC; Tiwari-Woodruff, SK | 1 |
| Beinhauer, A; Geirhos, B; Hempelmann, RG; Herzig, S; Jischa, J; Tacke, K | 1 |
| Ishii, A; Toyama, J | 1 |
| Courseau, C; Garay, R; Giraud, F; Hannaert, P; Pallotta, M; Rota, R | 1 |
| Alabaster, VA; Cheeseman, HE; Cooper, K; deSouza, RN; Keir, RF; Parry, MJ | 1 |
| Oide, H; Thurman, RG | 1 |
| Gil-Loyzaga, P; Merchàn-Pérez, A; Pérez-Cao, A; Tamargo, J | 1 |
| Fetkovska, N; Jakubovska, Z; Oravcova, J; Tison, P; Ulicna, L | 2 |
| Christensen, JD; Fjalland, B; Jørgensen, A; Treiman, M | 1 |
| Culliford, SJ; Ellory, JC; Knaus, EE; Smith, PA; Wolowyk, MW | 1 |
| Azzani, T; Bianchi, G; Casirati, P; Cusi, D; Muirhead, R; Reina, MC; Soldati, L; Vezzoli, G | 1 |
| Chaylakhyan, LM; Grishchenko, VM; Zherelova, OM | 1 |
| Ganunis, TF; Helfaer, MA; Hoehner, PJ; Kirsch, JR; Murphy, MT; Traystman, RJ | 1 |
| Hori, R; Komano, T; Saeki, T; Tanigawara, Y; Ueda, K | 1 |
| Gao, F; Imada, T; Ma, H; Nagata, T; Suzuki, K | 1 |
| Arnold, JM; Bailey, DG; Spence, JD | 1 |
| Brown, J; Butterworth, AR; Little, HJ; Rabbani, M | 1 |
| Kocmur, L; Zorec, R | 1 |
| Higashide, Y; Kase, N; Lee, B; Ohnishi, H; Takasaki, K; Tamura, N; Yamaura, T | 1 |
| Blumenfeld, H; Eliot, LS; Kandel, ER; Siegelbaum, SA | 1 |
| Chen, Y; Fukuo, K; Jiang, B; Kimura, T; Kitano, S; Koh, E; Morimoto, S; Ogihara, T; Sakakibara, S; Yasuda, O | 1 |
| Bachetti, T; Carboni, L; Ferri, S; Ratti, E; Spampinato, S; Van Amsterdam, FT | 1 |
| Chaignon, MM; Guédon, J; Mourad, JJ | 1 |
| Chiu, LM; Sitges, M | 1 |
| Dhein, S; Klaus, W; Salameh, A; Simsek, S; Zhao, Y | 1 |
| Gilar, M; Tesarová, E; Uhrová, M | 1 |
| Biancardi, E; Carbone, E; Clementi, F; Davalli, AM; Pollo, A; Pontiroli, AE; Pozza, G; Sher, E; Socci, C | 1 |
| Greto, L; Leonardi, A; Montagna, E; Sironi, G; Testa, R | 1 |
| Drímal, J; Kettmann, V; Svétlík, J | 1 |
| Accomazzo, MR; Bonfatti, M; Corsini, A; Fumagalli, R; Nicosia, S; Paoletti, R; Quarato, P; Raiteri, M; Sartani, A; Testa, R | 1 |
| Kikuchi, K; Sugawara, H; Tobise, K | 1 |
| Katoch, SS; Pfitzer, G; Rüegg, JC | 1 |
| Brauns, T; Glossmann, H; Haugland, RP; Kimball, SD; Prinz, H; Striessnig, J | 1 |
| Ebisu, H; Egi, Y; Fujino, Y; Hayashi, K; Inoue, S; Kido, H; Kubo, Y; Nakamura, N; Nishikawa, M; Ohtaki, Y; Uchida, T; Yamanaga, K | 1 |
| Andreas, K; Bräter, M; Li, SN | 1 |
| Costa, B; Giusti, L; Lucacchini, A; Martini, C | 1 |
| Gohda, M; Kido, H; Matzno, S; Nakamura, N; Nishikawa, M; Shinyama, H; Yamanaga, K | 1 |
| Garrigos, M; Orlowski, S; Pascaud, C | 1 |
| Combs, JD; England, BP; Gordeev, MF; Gordon, EM; Jonnalagadda, S; Patel, DV | 1 |
| Katz, E; Konnerth, A; Plant, TD; Schirra, C; Uchitel, OD | 1 |
| Adachi-Akahane, S; Kanda, S; Nagao, T | 1 |
| Accomazzo, MR; Bernini, F; Canavesi, M; Catapano, AL; Corsini, A; Fumagalli, R; Paoletti, R; Sartani, A; Testa, R | 1 |
| Amoroso, S; Annunziato, L; Cataldi, M; de Caprariis, P; di Renzo, G; Palagiano, F; Secondo, A; Taglialatela, M | 1 |
| Guppy, LJ; Littleton, JM | 2 |
| Berkels, R; Dhein, S; Klaus, W; Salameh, A | 1 |
| Allen, BG; Fareh, S; Gaspo, R; Hebert, TE; Levi, M; Nattel, S; Sun, H; Yue, L | 1 |
| Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S | 1 |
| Hohenegger, M; Kress, HG; Weigl, LG | 1 |
| Arh, M; Budihna, MV | 1 |
| Hayashi, K; Matsumura, Y | 1 |
| Cathala, L; Chesnoy-Marchais, D | 1 |
| Li, ZC; Mei, QB; Song, JC; Zhang, FQ; Zhao, DH | 1 |
| Celis, H; Fagard, RH; Gasowski, J; Staessen, JA; Thijs, L; Wang, JG | 1 |
| Ochi, R; Sonoda, S | 1 |
| Hino, N; Masumiya, H; Ochi, R; Tsujikawa, H | 1 |
| Bell-Horner, CL; Chen, ZL; Covey, DF; Das, P; Dillon, GH; Gonzales, EB; Huang, RQ; Raut, A | 1 |
| Birkenhäger, WH; Bulpitt, CJ; Celis, H; de Leeuw, PW; Fagard, R; Fletcher, AE; Forette, F; Leonetti, G; McCormack, P; Nachev, C; O'Brien, E; Rodicio, JL; Rosenfeld, J; Sarti, C; Staessen, JA; Thijisq, L; Tuomilehto, J; Webster, J; Yodfat, Y; Zanchetti, A | 1 |
| Gupta, A; Mao, Q; Unadkat, JD; Vethanayagam, RR; Wang, H; Zhang, Y; Zhou, L | 1 |
| Inoue, H; Kikuchi, S; Matsui, T; Nakamura, K; Yamagishi, S | 1 |
| Arai, Y; Fujiwara, M; Harada, M; Kinoshita, H; Kuwabara, Y; Kuwahara, K; Murakami, M; Nakagawa, Y; Nakanishi, M; Nakao, K; Takano, M; Ueshima, K; Yasuno, S | 1 |
| Cheng, XW; Hirashiki, A; Izawa, H; Jin, Z; Kuzuya, M; Murohara, T; Nagata, K; Nishizawa, T; Noda, A; Obata, K; Okumura, K; Sasaki, T; Shi, GP; Takeshita, K | 1 |
| Aktay, G; Emre, MH; Polat, A | 1 |
| Krzemiński, TF; Mitręga, KA; Porc, M; Varghese, B | 1 |
| Arai, Y; Cho, K; Kamakura, S; Kangawa, K; Kimura, T; Kinoshita, H; Kiyonaka, S; Kuwabara, Y; Kuwahara, K; Minami, T; Mori, Y; Nakagawa, Y; Nakao, K; Nishida, M; Nishikimi, T; Shibata, J; Ueshima, K; Yamada, C; Yamada, Y; Yasuno, S | 1 |
| Chudoba, D; Drużbicki, K; Jarek, M; Jenczyk, J; Kiwilsza, A; Mielcarek, J; Pajzderska, A; Wąsicki, J | 1 |
6 review(s) available for nitrendipine and dihydropyridines
| Article | Year |
|---|---|
Differential effects of 1,4-dihydropyridine calcium channel blockers: therapeutic implications.
Topics: Angina Pectoris; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Hemodynamics; Humans; Hypertension; Nifedipine; Nitrendipine | 1987 |
Are dihydropyridine binding sites voltage sensitive calcium channels?
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Ion Channels; Muscle, Smooth; Muscles; Myocardium; Neurons; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyridines | 1984 |
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cerebrovascular Circulation; Cerebrovascular Disorders; Coronary Disease; Diabetes Mellitus; Dihydropyridines; Female; Humans; Hypertension; Ketamine; Magnesium; Magnesium Deficiency; Microcirculation; Muscle, Smooth, Vascular; Muscles; Nifedipine; Nisoldipine; Nitrendipine; Nutritional Requirements; Pentobarbital; Pre-Eclampsia; Pregnancy; Pyridines; Rats; Vasoconstrictor Agents; Vasodilator Agents; Venules | 1984 |
Grapefruit juice and drugs. How significant is the interaction?
Topics: Beverages; Biological Availability; Citrus; Dihydropyridines; Drug Interactions; Felodipine; Flavanones; Flavonoids; Half-Life; Humans; Nifedipine; Nitrendipine | 1994 |
Dual mode of action of dihydropyridine calcium antagonists: a role for nitric oxide.
Topics: Angina Pectoris; Animals; Calcium; Clinical Trials as Topic; Dihydropyridines; Humans; Hypertension; Nitrendipine; Nitric Oxide; Time Factors | 1999 |
Vatanidipine hydrochloride: a new long-lasting antihypertensive agent.
Topics: Animals; Antihypertensive Agents; Arteriosclerosis; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Humans; Hypertension; Nitrendipine | 2001 |
6 trial(s) available for nitrendipine and dihydropyridines
| Article | Year |
|---|---|
Acute and chronic effects of dihydropyridines on triglycerides in humans.
Topics: Adult; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Random Allocation; Triglycerides | 1988 |
Effects of dihydropyridines and their combination with aspirin on blood pressure and circadian platelet activity in patients with essential hypertension.
Topics: Adult; Aspirin; Blood Platelets; Blood Pressure; Circadian Rhythm; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Isradipine; Male; Middle Aged; Nitrendipine | 1994 |
Treatment of hypertension with dihydropyridine calcium antagonists and aspirin.
Topics: Adult; Aspirin; Blood Platelets; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Isradipine; Male; Middle Aged; Nitrendipine | 1994 |
Comparative effects of antihypertensive drugs on systolic blood pressure.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Nitrendipine; Time Factors; Vasodilator Agents | 1993 |
Dihydropyridine calcium-channel blockers for antihypertensive treatment in older patients--evidence from the Systolic Hypertension in Europe Trial.
Topics: Aged; Alcohol Drinking; Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Double-Blind Method; Europe; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Prognosis; Smoking; Treatment Outcome | 2001 |
Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus; Dihydropyridines; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Europe; Female; Follow-Up Studies; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Incidence; Linear Models; Male; Myocardial Infarction; Nitrendipine; Stroke; Survival Rate; Time Factors; Treatment Outcome | 2004 |
163 other study(ies) available for nitrendipine and dihydropyridines
| Article | Year |
|---|---|
Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Dogs; Heart Rate; Hypertension; Hypertension, Renal; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Wistar | 1992 |
Ion dependence of the partially purified mitochondrial dihydropyridine Ca2+ antagonist receptor.
Topics: Animals; Anions; Binding Sites; Calcium Channels; Cations; Dihydropyridines; Guinea Pigs; Kinetics; Mitochondria, Liver; Nitrendipine; Receptors, Nicotinic; Tritium | 1992 |
Alteration of voltage-dependent calcium channels in canine brain during global ischemia and reperfusion.
Topics: Animals; Binding Sites; Brain Ischemia; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Dihydropyridines; Dogs; Female; Isradipine; Nitrendipine; Reperfusion; Synaptosomes | 1992 |
Reversal of multidrug resistance by B859-35, a metabolite of B859-35, niguldipine, verapamil and nitrendipine.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Division; Dihydropyridines; Drug Resistance; Humans; Membrane Glycoproteins; Nitrendipine; Rats; Rhodamines; Verapamil | 1992 |
Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cells, Cultured; Dihydropyridines; Fatty Acids, Unsaturated; Fish Oils; Heart; In Vitro Techniques; Ion Channel Gating; Myocardial Contraction; Nitrendipine; Ouabain; Rats; Verapamil | 1992 |
Dihydropyridine-sensitive L-type Ca2+ channels in human foreskin fibroblast cells. Characterization of activation with the growth factor Lys-bradykinin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channels; Cells, Cultured; Dihydropyridines; Fibroblasts; Fura-2; Humans; Ion Channel Gating; Kallidin; Nitrendipine | 1992 |
Activation of voltage-dependent calcium channels of mammalian sperm is required for zona pellucida-induced acrosomal exocytosis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acrosome; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cattle; Dihydropyridines; Exocytosis; Isradipine; Male; Mice; Nitrendipine; Sheep; Spermatozoa; Zona Pellucida | 1992 |
In vitro and ex vivo Ca-antagonistic effect of 2-methoxyethyl(E)-3-phenyl-2-propen-1-yl(+/-)-1,4-dihydro-2,6-dimethyl- 4-(3- nitrophenyl)pyridine-3,5-dicarboxylate (FRC-8653), a new dihydropyridine derivative.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Calcium; Calcium Channel Blockers; Dihydropyridines; Heart; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrendipine; PC12 Cells; Potassium Chloride; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1992 |
Intervascular and stimulus selectivity of nitrendipine and related derivatives in KCl and prostaglandin F2 alpha precontracted porcine arteries.
Topics: Animals; Basilar Artery; Coronary Vessels; Dihydropyridines; Dinoprost; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Potassium Chloride; Swine; Vasodilation; Vasodilator Agents | 1992 |
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil | 1992 |
Effects of dihydropyridines and inorganic calcium blockers on aggregation and on intracellular free calcium in platelets.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Female; Humans; Male; Nimodipine; Nisoldipine; Nitrendipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium; Thrombin | 1991 |
Kinetics of binding of dihydropyridine calcium channel ligands to skeletal muscle membranes: evidence for low-affinity sites and for the involvement of G proteins.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Isradipine; Kinetics; Ligands; Membrane Proteins; Microsomes; Muscles; Nitrendipine; Oxadiazoles; Rabbits; Receptors, Nicotinic; Stereoisomerism; Thionucleotides | 1991 |
Active conformation of 1,4-dihydropyridine calcium entry blockers. Effect of size of 2-aryl substituent on rotameric equilibria and receptor binding.
Topics: Animals; Aorta; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Chemical Phenomena; Chemistry; Dihydropyridines; Guinea Pigs; Halogens; Male; Molecular Conformation; Molecular Structure; Muscle Relaxation; Muscle, Smooth, Vascular; Muscles; Nitrendipine; Receptors, Nicotinic; Structure-Activity Relationship | 1991 |
Neuropsychopharmacological studies of a Ca2+ channel blocker on the modulation of brain Ca2+ mobilization of spontaneously hypertensive rats under mild stress.
Topics: Acoustic Stimulation; Animals; Binding Sites; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Diazepam; Dihydropyridines; Hippocampus; Isoindoles; Isradipine; Kinetics; Male; Motor Activity; Nitrendipine; Organ Specificity; Piperazines; Pyrimidines; Rats; Rats, Inbred SHR; Reference Values; Stress, Psychological; Synaptosomes | 1991 |
NZ-105, a new 1,4-dihydropyridine derivative: correlation between dihydropyridine receptor binding and inhibition of calcium uptake in rabbit aorta.
Topics: Animals; Antihypertensive Agents; Aorta; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Dihydropyridines; In Vitro Techniques; Kinetics; Male; Membranes; Microsomes; Muscle, Smooth, Vascular; Nitrendipine; Nitrophenols; Organophosphorus Compounds; Rabbits; Receptors, Nicotinic; Time Factors; Tritium | 1991 |
Modulation of dihydropyridine-sensitive calcium channels: a role for G proteins.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Dihydropyridines; GTP-Binding Proteins; Guanosine Triphosphate; Isradipine; Neurons; Nitrendipine; Oxadiazoles; Rats; Tumor Cells, Cultured | 1990 |
Lacidipine: a calcium antagonist with potent and long-lasting antihypertensive effects in animal studies.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dogs; Guinea Pigs; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Nitrendipine; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Species Specificity; Vasoconstriction | 1990 |
Comparative studies with enantiomers of dihydropyridine ligands suggests that there are multiple binding sites associated with the calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain Chemistry; Calcium Channels; Dihydropyridines; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Ligands; Male; Mice; Muscle, Smooth; Myocardium; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Stereoisomerism | 1990 |
Inhibition of calcium currents in cultured myenteric neurons by neuropeptide Y: evidence for direct receptor/channel coupling.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cells, Cultured; Dihydropyridines; Fura-2; Membrane Potentials; Myenteric Plexus; Neurons; Neuropeptide Y; Nitrendipine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Neuropeptide Y; Receptors, Neurotransmitter; Virulence Factors, Bordetella | 1990 |
Voltage-dependent calcium currents in Purkinje cells from rat cerebellar vermis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Barium; Calcium Channels; Cell Separation; Dihydropyridines; Electric Conductivity; Electrophysiology; Nickel; Nimodipine; Nitrendipine; Purkinje Cells; Rats | 1991 |
Different sensitivities to dihydropyridines of catecholamine release from cat and ox adrenals.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Catecholamines; Cats; Cattle; Dihydropyridines; In Vitro Techniques; Isradipine; Male; Nitrendipine; Perfusion; Species Specificity | 1990 |
The hemodynamic effects of lacidipine in anesthetized dogs: comparison with nitrendipine, amlodipine, verapamil, and diltiazem.
Topics: Amlodipine; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Stroke Volume; Vascular Resistance; Verapamil | 1991 |
Electrophysiological effects of CD-349, a dihydropyridine-type calcium antagonist, on goat cardiac Purkinje fibers.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Dihydropyridines; Electrophysiology; Goats; In Vitro Techniques; Microelectrodes; Nifedipine; Nitrendipine; Purkinje Fibers | 1991 |
Effect of S-312, a new calcium channel blocker, on the 1,4-dihydropyridine binding sites in porcine basilar blood vessels and rat aortic smooth muscle cells.
Topics: Animals; Aorta; Basilar Artery; Binding Sites; Calcium; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Isradipine; Muscle, Smooth, Vascular; Nicardipine; Nitrendipine; Oxadiazoles; Rats; Swine | 1991 |
Chronic dihydropyridine treatment can reverse the behavioural consequences of and prevent adaptations to, chronic ethanol treatment.
Topics: Adaptation, Psychological; Administration, Inhalation; Animals; Behavior, Animal; Bicuculline; Brain; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Ethanol; Isradipine; Male; Mice; Mice, Inbred C57BL; Nimodipine; Nitrendipine; Seizures; Substance Withdrawal Syndrome | 1991 |
Identification of the site of interaction of the dihydropyridine channel blockers nitrendipine and azidopine with the calcium-channel alpha 1 subunit.
Topics: Amino Acid Sequence; Animals; Azides; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Dihydropyridines; Kinetics; Models, Biological; Molecular Sequence Data; Muscles; Myocardium; Nitrendipine; Peptide Fragments; Rabbits | 1991 |
Ca2+ channels in rat central and peripheral neurons: high-threshold current resistant to dihydropyridine blockers and omega-conotoxin.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Central Nervous System; Differential Threshold; Dihydropyridines; Drug Resistance; Electrophysiology; Kinetics; Neurons; Nitrendipine; omega-Conotoxin GVIA; Osmolar Concentration; Peptides, Cyclic; Peripheral Nerves; Rats | 1991 |
Pharmacological profiles of YM-16151-1 and its optical isomers: a novel calcium entry blocking and selective beta-1 adrenoceptor blocking agent.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Nitrendipine; Nitrophenols; Rabbits; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship | 1990 |
Effects of a new 1,4-dihydropyridine, lacidipine, on gastrointestinal motility and other gastrointestinal functions.
Topics: Animals; Calcium Channel Blockers; Defecation; Digestive System; Dihydropyridines; Dogs; Electrophysiology; Female; Gastric Emptying; Gastric Mucosa; Gastrointestinal Motility; Histamine; In Vitro Techniques; Male; Muscle, Smooth; Nitrendipine; Rats | 1990 |
Effect of inorganic calcium channel blockers on dihydropyridine binding to cardiac sarcolemma.
Topics: Animals; Cadmium; Calcimycin; Calcium; Calcium Channel Blockers; Dihydropyridines; Dogs; In Vitro Techniques; Isradipine; Lanthanum; Myocardium; Nitrendipine; Ouabain; Oxadiazoles; Quinuclidinyl Benzilate; Sarcolemma | 1990 |
Dihydropyridine binding to the L-type Ca2+ channel in rabbit heart sarcolemma and skeletal muscle transverse-tubules: role of disulfide, sulfhydryl and phosphate groups.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport, Active; Calcium Channels; Calmodulin; Dihydropyridines; Disulfides; Dithiothreitol; Glutathione; Iodoacetamide; Muscles; Myocardium; Nitrendipine; Phosphorylation; Protein Kinases; Rabbits; Sarcolemma; Sulfhydryl Compounds | 1990 |
Genetic regulation of dihydropyridine-sensitive calcium channels in brain may determine susceptibility to physical dependence on alcohol.
Topics: Alcoholism; Animals; Brain Chemistry; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Ethanol; Female; Gene Expression Regulation; Kinetics; Mice; Nitrendipine; Seizures; Substance Withdrawal Syndrome; Up-Regulation | 1990 |
Cortical dihydropyridine binding sites and a behavioral syndrome in morphine-abstinent rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Dihydropyridines; Hippocampus; Male; Morphine Dependence; Naloxone; Nifedipine; Nitrendipine; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Substance Withdrawal Syndrome | 1990 |
Allosteric interaction of trimebutine maleate with dihydropyridine binding sites.
Topics: Animals; Binding Sites; Calcium; Calcium Channels; Cecum; Dihydropyridines; Guinea Pigs; Ileum; Kinetics; Membranes; Muscle Contraction; Muscle, Smooth; Nitrendipine; Potassium; Trimebutine; Tritium | 1990 |
4-Alkyl-1,4-dihydropyridines derivatives as specific PAF-acether antagonists.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Platelets; Blood Pressure; Chemical Phenomena; Chemistry; Dihydropyridines; Heart Rate; Ileum; Male; Microsomes; Molecular Structure; Muscle Contraction; Myocardial Contraction; Nitrendipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1990 |
[3H]-nitrendipine binding in normal and cardiomyopathic hamster hearts: modulation by temperature, verapamil and diltiazem.
Topics: Allosteric Regulation; Animals; Binding Sites; Calcium Channels; Cardiomyopathies; Cricetinae; Dihydropyridines; Diltiazem; In Vitro Techniques; Kinetics; Male; Myocardium; Nitrendipine; Temperature; Verapamil | 1990 |
Design of an antithrombotic-antihypertensive agent (Wy 27569). Synthesis and evaluation of a series of 2-heteroaryl-substituted dihydropyridines.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antihypertensive Agents; Chemical Phenomena; Chemistry; Dihydropyridines; Drug Design; Fibrinolytic Agents; Humans; Hypertension; Imidazoles; Nitrendipine; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Thromboxane B2; Thromboxane-A Synthase | 1990 |
Dihydropyrimidine calcium channel blockers: 2-heterosubstituted 4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines.
Topics: Animals; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Guinea Pigs; Molecular Conformation; Muscle, Smooth, Vascular; Nitrendipine; Pyrimidines; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship | 1990 |
Enantioselective determination of felodipine and other chiral dihydropyridine calcium entry blockers in human plasma.
Topics: Calcium Channel Blockers; Chromatography, Gas; Chromatography, High Pressure Liquid; Dihydropyridines; Felodipine; Humans; Male; Nitrendipine; Stereoisomerism | 1990 |
High and low affinity states of the dihydropyridine and phenylalkylamine receptors on the cardiac calcium channel and their interconversion by divalent cations.
Topics: Animals; Calcium; Cations, Divalent; Chickens; Dihydropyridines; Heart; Ion Channels; Isradipine; Magnesium; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1985 |
Stimulation of calcium uptake in PC12 cells by the dihydropyridine agonist BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Nifedipine; Nitrendipine; Pheochromocytoma; Pyridines; Rats | 1985 |
Decreased [3H]nitrendipine binding in the brainstem of deoxycorticosterone-NaCl hypertensive rats.
Topics: Animals; Brain Stem; Calcium; Desoxycorticosterone; Dihydropyridines; Hypertension; Ion Channels; Kidney; Kinetics; Male; Myocardium; Nephrectomy; Nifedipine; Nitrendipine; Organ Size; Pyridines; Rats; Sodium Chloride | 1985 |
Profile of the oppositely acting enantiomers of the dihydropyridine 202-791 in cardiac preparations: receptor binding, electrophysiological, and pharmacological studies.
Topics: Animals; Binding, Competitive; Calcium; Dihydropyridines; Dogs; Electric Conductivity; Guinea Pigs; Heart; Ion Channels; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Papillary Muscles; Pyridines; Sarcolemma; Stereoisomerism; Ventricular Function | 1985 |
Effects of nitrendipine on the voltage-sensitive calcium channel in mammalian sensory neurons.
Topics: Action Potentials; Animals; Cells, Cultured; Dihydropyridines; Electric Stimulation; Ethanol; Ganglia, Spinal; Ion Channels; Mice; Nerve Growth Factors; Neurons, Afferent; Nifedipine; Nitrendipine; Pharmaceutical Vehicles; Pyridines; Reaction Time; Temperature | 1985 |
Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bucladesine; Calcium; Cell Differentiation; Dihydropyridines; Nerve Growth Factors; Nifedipine; Nitrendipine; Norepinephrine; Pheochromocytoma; Potassium; Pyridines; Rats; Secretory Rate | 1986 |
Calcium channels in muscle cells isolated from rat mesenteric arteries: modulation by dihydropyridine drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Pyridines; Rats | 1986 |
BAY k 8644, a calcium channel agonist, reverses hypotension in endotoxin-shocked rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Male; Microsomes; Myocardium; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Shock, Septic | 1986 |
Diethyl 3,6-dihydro-2,4-dimethyl-2,6-methano-1,3-benzothiazocine-5,11- dicarboxylates as calcium entry antagonists: new conformationally restrained analogues of Hantzsch 1,4-dihydropyridines related to nitrendipine as probes for receptor-site conformation
Topics: Animals; Aorta; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Dose-Response Relationship, Drug; Heterocyclic Compounds; Ion Channels; Male; Nitrendipine; Protein Binding; Pyridines; Rats; Rats, Inbred Strains; Sarcolemma; Structure-Activity Relationship; Swine; Terpenes | 1987 |
A comparison between the binding and electrophysiological effects of dihydropyridines on cardiac membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Heart; Ion Channels; Isradipine; Kinetics; Membrane Potentials; Membranes; Myocardium; Nicotinic Acids; Nimodipine; Nitrendipine; Oxadiazoles; Pyridines; Stereoisomerism; Structure-Activity Relationship | 1987 |
Dihydropyridine-sensitive Ca2+ channels and inositol phospholipid metabolism in ethanol physical dependence.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alcoholism; Animals; Cerebral Cortex; Dihydropyridines; Hydroxydopamines; In Vitro Techniques; Inositol Phosphates; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nitrendipine; Oxidopamine; Pyridines; Rats; Rats, Inbred Strains; Sugar Phosphates; Vas Deferens | 1987 |
MDL 72567, a dihydropyridine calcium-antagonist, that causes vasodilation and direct sinus bradycardia.
Topics: Animals; Bradycardia; Calcium Channel Blockers; Calcium Channels; Decerebrate State; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Guinea Pigs; Hypertension, Renal; Male; Nicotinic Acids; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Vasodilation | 1987 |
Dihydropyridine calcium antagonists and agonists in the isolated perfused Dahl rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Glomerular Filtration Rate; Hypertension, Renal; In Vitro Techniques; Ion Channels; Kidney; Male; Nitrendipine; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Renal Circulation; Sodium Chloride; Verapamil | 1987 |
Calcium antagonist binding in cat brain tolerant to electroconvulsive shock.
Topics: Animals; Binding Sites; Brain; Cats; Cerebellum; Cerebral Cortex; Dihydropyridines; Electroshock; Female; Hippocampus; Ion Channels; Male; Nitrendipine; Pyridines; Tissue Distribution | 1987 |
Altered characteristics of catecholamine release from rat cortical slices and bovine adrenal chromaffin cells in culture after chronic exposure to ethanol and the effect of the dihydropyridine drugs on these systems.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Carbachol; Catecholamines; Cattle; Cerebral Cortex; Chromaffin System; Corpus Striatum; Dihydropyridines; Ethanol; Nitrendipine; Rats | 1987 |
Pharmacological characterization of two calcium currents in GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Dihydropyridines; Electrophysiology; Ion Channels; Nitrendipine; Osmolar Concentration; Pituitary Gland; Rats | 1988 |
Dihydropyridine-sensitive Ca2+ channel in aneurally cultured human muscles. Relationship between high-affinity binding site and inhibition of calcium uptake.
Topics: Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cells, Cultured; Dihydropyridines; Electrophysiology; Humans; Ion Channels; Isradipine; Muscles; Nitrendipine; Oxadiazoles; Potassium | 1988 |
Omega-conotoxin binding and effects on calcium channel function in human neuroblastoma and rat pheochromocytoma cell lines.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Dihydropyridines; Humans; Ion Channels; Mollusk Venoms; Neuroblastoma; Nitrendipine; omega-Conotoxins; Pheochromocytoma; Potassium; Rats; Tumor Cells, Cultured | 1988 |
Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; gamma-Aminobutyric Acid; Ion Channels; Isradipine; Lanthanum; Male; Mice; Neurotransmitter Agents; Nifedipine; Nitrendipine; Oxadiazoles; Potassium; Receptors, Nicotinic; Ruthenium Red; Synaptosomes | 1988 |
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil | 1988 |
Dihydropyridine-sensitive calcium channel activity related to prolactin, growth hormone, and luteinizing hormone release from anterior pituitary cells in culture: interactions with somatostatin, dopamine, and estrogens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Calcium Radioisotopes; Cells, Cultured; Dihydropyridines; Dopamine; Estradiol; Female; Growth Hormone; Luteinizing Hormone; Male; Nitrendipine; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Potassium; Prolactin; Rats; Rats, Inbred Strains; Sex Characteristics; Somatostatin | 1988 |
Potential-dependent interactions of nitrendipine and related 1,4-dihydropyridines in functional smooth muscle preparations.
Topics: Animals; Calcium; Dihydropyridines; Electrophysiology; Guinea Pigs; Ileum; In Vitro Techniques; Muscle, Smooth; Nitrendipine; Potassium | 1988 |
Pharmacologic effects of Wy 27569: a combined calcium channel blocker and thromboxane synthetase inhibitor.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; In Vitro Techniques; Male; Nitrendipine; Prostaglandins F; Rats; Rats, Inbred SHR; Thromboxane B2; Thromboxane-A Synthase | 1989 |
Voltage-dependent calcium channels in skeletal muscle transverse tubules. Measurements of calcium efflux in membrane vesicles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzothiazoles; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Carbocyanines; Cell Membrane; Dihydropyridines; Edetic Acid; Fluorescent Dyes; Isradipine; Lanthanum; Membrane Potentials; Muscles; Nitrendipine; Oxadiazoles; Potassium; Rabbits; Verapamil | 1989 |
Photoaffinity labeling with dihydropyridine derivatives of crude membranes from rat skeletal, cardiac, ileal, and uterine muscles and whole brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Autoradiography; Brain; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Female; Ileum; In Vitro Techniques; Male; Membranes; Muscle, Smooth; Muscles; Myocardium; Nitrendipine; Rats; Spectrometry, Fluorescence; Uterus | 1989 |
LY249933: a cardioselective 1,4-dihydropyridine with positive inotropic activity.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Dihydropyridines; Dogs; Electrocardiography; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardial Contraction; Nitrendipine; Potassium Chloride; Stereoisomerism; Stimulation, Chemical | 1989 |
Cortical dihydropyridine binding sites are unaltered in human alcoholic brain.
Topics: Alcoholism; Cerebral Cortex; Dihydropyridines; Humans; Isradipine; Male; Middle Aged; Nitrendipine; Oxadiazoles | 1989 |
Improved radioreceptor assay for the determination of plasma levels of dihydropyridine calcium channel blockers in humans.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Isradipine; Male; Mass Spectrometry; Nicardipine; Nitrendipine; Pyridines; Radioligand Assay; Rats; Rats, Inbred Strains | 1989 |
Evidence of altered dihydropyridine receptor binding capacity following cardiac transplantation.
Topics: Animals; Binding, Competitive; Calcium Channels; Dihydropyridines; Dogs; Graft Rejection; Heart Transplantation; Nifedipine; Nitrendipine; Receptors, Nicotinic; Sarcolemma; Verapamil | 1989 |
New 1,4-dihydropyridine derivatives combining calcium antagonism and alpha-adrenolytic properties.
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Chloride; Cerebral Cortex; Chemical Phenomena; Chemistry; Coronary Vessels; Dihydropyridines; Guinea Pigs; Male; Molecular Structure; Muscle Contraction; Nitrendipine; Prazosin; Rats; Receptors, Adrenergic, alpha; Swine; Vas Deferens; Yohimbine | 1989 |
Reversible dihydropyridine isothiocyanate binding to brain calcium channels.
Topics: Animals; Brain; Calcium; Dihydropyridines; Ion Channels; Isothiocyanates; Kinetics; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Thiocyanates | 1985 |
Calcium channels in rat brain synaptosomes: identification and pharmacological characterization. High affinity blockade by organic Ca2+ channel blockers.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Ion Channels; Male; Nifedipine; Nitrendipine; Norepinephrine; Potassium; Pyridines; Rats; Rats, Inbred Strains; Synaptosomes | 1985 |
Dihydropyridine sensitive calcium channels in a smooth muscle cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Cobalt; Dihydropyridines; Ion Channels; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium; Pyridines; Rats | 1985 |
Inhibition of 3H-nitrendipine binding in rat aortic and cerebral cortex membranes by the new dihydropyridine calcium antagonist benidipine hydrochloride.
Topics: Animals; Aorta; Binding, Competitive; Calcium Channel Blockers; Cerebral Cortex; Dihydropyridines; In Vitro Techniques; Male; Membranes; Microsomes; Myocardium; Nitrendipine; Rats; Rats, Inbred Strains; Stereoisomerism | 1989 |
Cobalt-sensitive and dihydropyridine-insensitive stimulation of dopamine release from tuberoinfundibular neurons by high extracellular concentrations of barium ions.
Topics: Animals; Barium; Cations, Divalent; Cobalt; Dihydropyridines; Dopamine; Female; Hypothalamus; Nitrendipine; Rats; Rats, Inbred Strains | 1989 |
Uptake of CD-349 and nitrendipine into bovine intrapulmonary artery and vein.
Topics: 2,4-Dinitrophenol; Animals; Cattle; Dihydropyridines; Dinitrophenols; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Nitrendipine; Pulmonary Artery; Pulmonary Veins; Temperature; Uncoupling Agents | 1989 |
Isolation from rat brain tissue of an inhibiting activity for dihydropyridine binding sites and voltage-dependent CA2+ uptake.
Topics: Animals; Brain; Calcium; Calcium Channels; Dihydropyridines; Hippocampus; In Vitro Techniques; Nitrendipine; Rats; Receptors, Nicotinic | 1987 |
Voltage-dependent Ca2+ channels in primary cultures of cerebellar granule cells: modulatory action by an endogenous ligand.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebellum; Dihydropyridines; Nitrendipine; Rats; Receptors, Nicotinic; Veratridine | 1988 |
[Reconstruction of a purified and functionally active dihydropyridine-sensitive calcium channel into liposomes].
Topics: Animals; Biological Transport; Calcium Channels; Dihydropyridines; In Vitro Techniques; Liposomes; Nitrendipine; Rabbits; Receptors, Nicotinic | 1988 |
The mitochondrial high-capacity low-affinity (+/-)-[3H]nitrendipine binding site is regulated by nucleotides.
Topics: Adenosine Triphosphate; Animals; Calcium Channels; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Intracellular Membranes; Kinetics; Mitochondria; Nitrendipine; Purine Nucleotides; Pyrimidine Nucleotides; Receptors, Nicotinic | 1988 |
Synthesis and calcium channel antagonist activity of nifedipine analogues containing 1,2-dihydropyridyl in place of the 1,4-dihydropyridyl moiety.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Intestine, Small; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; Structure-Activity Relationship | 1988 |
Phencyclidine increases the affinity of dihydropyridine calcium channel antagonist binding in rat brain.
Topics: Animals; Binding Sites; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Kinetics; Magnesium; Male; Nifedipine; Nitrendipine; Phencyclidine; Pyridines; Rats; Rats, Inbred Strains | 1985 |
Atrial natriuretic peptide in human essential hypertension.
Topics: Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Middle Aged; Nitrendipine; Pyridines | 1987 |
Effect of divalent cation chelation on dihydropyridine binding in isolated cardiac sarcolemma vesicles.
Topics: Animals; Calcimycin; Calcium; Cations, Divalent; Dihydropyridines; Dogs; Edetic Acid; Hydrogen-Ion Concentration; Isradipine; Magnesium; Myocardium; Nitrendipine; Ouabain; Oxadiazoles; Phosphates; Sarcolemma | 1988 |
Dihydropyridine calcium channel antagonists binding in non-mammalian vertebrates: characterization and relationship to 'peripheral-type' binding sites for benzodiazepines.
Topics: Animals; Brain; Calcium Channels; Columbidae; Dihydropyridines; Female; Kinetics; Lizards; Male; Membranes; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rana catesbeiana; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Nicotinic; Species Specificity; Trout | 1986 |
High-affinity antibodies to the 1,4-dihydropyridine Ca2+-channel blockers.
Topics: Animals; Antibodies; Antibody Specificity; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Nifedipine; Nitrendipine; Pyridines; Rabbits; Receptors, Nicotinic; Structure-Activity Relationship; Tritium | 1986 |
An antibody to dihydropyridine calcium entry blockers. A comparison with the calcium channel receptor in skeletal muscle.
Topics: Antibodies; Antibody Affinity; Antibody Specificity; Antigens; Calcium Channel Blockers; Calcium Channels; Chemical Phenomena; Chemistry; Dihydropyridines; Haptens; Muscles; Nitrendipine; Pyridines; Receptors, Nicotinic | 1986 |
Gonadotropin-releasing hormone-induced Ca2+ transients in single identified gonadotropes require both intracellular Ca2+ mobilization and Ca2+ influx.
Topics: Animals; Calcium; Cells, Cultured; Dihydropyridines; Female; Gonadotropin-Releasing Hormone; Nitrendipine; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains | 1988 |
Phosphorylation of ventricular sarcolemmal membranes does not alter binding properties of nitrendipine.
Topics: Alamethicin; Animals; Cats; Dihydropyridines; Dose-Response Relationship, Drug; Female; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Phosphorylation; Protein Kinases; Pyridines; Sarcolemma; Time Factors | 1985 |
Effects of mercaptans upon dihydropyridine binding sites on transverse tubules isolated from triads of rabbit skeletal muscle.
Topics: Animals; Digoxin; Dihydropyridines; Dithiothreitol; Glutathione; Glutathione Disulfide; Muscles; Nifedipine; Nitrendipine; Ouabain; Pyridines; Rabbits; Sulfhydryl Compounds | 1985 |
Synthesis, platelet aggregation inhibitory activity, and in vivo antithrombotic activity of new 1,4-dihydropyridines.
Topics: Animals; Cats; Collagen; Dihydropyridines; Humans; Kinetics; Male; Mice; Nitrendipine; Platelet Aggregation; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thrombosis | 1988 |
Interaction between propranolol and calcium channel blockers in cardiac and vascular smooth muscle.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Guinea Pigs; Heart; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Nitrendipine; Propranolol | 1988 |
A novel 1,4-dihydropyridine-binding site on mitochondrial membranes from guinea-pig heart, liver and kidney.
Topics: Animals; Binding Sites; Centrifugation, Density Gradient; Dihydropyridines; Diltiazem; Guinea Pigs; Intracellular Membranes; Kidney; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Nitrendipine; Osmolar Concentration; Subcellular Fractions; Verapamil | 1988 |
In vitro and in vivo characterization of 2,6-dimethyl-3,5-dicarbomethoxy-4-(2-isothiocyano)phenyl-1,4- dihydropy ridine as a Ca2+ channel antagonist.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Colon; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Isothiocyanates; Male; Membrane Proteins; Muscle, Smooth, Vascular; Nitrendipine; Portal Vein; Potassium; Quinuclidinyl Benzilate; Rats; Rats, Inbred SHR; Receptors, Muscarinic; Thiocyanates; Urinary Bladder | 1987 |
The interaction of phenylalkylamine calcium channel blockers with the 1,4-dihydropyridine binding site.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Dihydropyridines; Heart; Kinetics; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Drug; Structure-Activity Relationship; Verapamil | 1986 |
Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.
Topics: Animals; Binding Sites; Cattle; Dihydropyridines; Electrophysiology; Heart Conduction System; Ion Channels; Membrane Potentials; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Pyridines; Verapamil | 1984 |
Comparative structure-activity relationships for dihydropyridines as inhibitors of [3H]-nitrendipine binding vs cyclic nucleotide phosphodiesterases.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Binding, Competitive; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Kinetics; Male; Myocardium; Nifedipine; Nitrendipine; Pyridines; Rats; Structure-Activity Relationship | 1984 |
Molecular properties of the slow inward calcium channel. Molecular weight determinations by radiation inactivation and covalent affinity labeling.
Topics: Affinity Labels; Animals; Calcium; Dihydropyridines; Guinea Pigs; Ion Channels; Methods; Molecular Weight; Muscles; Nifedipine; Nitrendipine; Pyridines | 1983 |
Diazepam-stimulated increases in the synaptosomal uptake of 45Ca2+: reversal by dihydropyridine calcium channel antagonists.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Calcium Radioisotopes; Cerebral Cortex; Diazepam; Dihydropyridines; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Synaptosomes | 1984 |
Inhibition by dihydropyridines of regulatory volume decrease and osmolyte fluxes in cultured astrocytes is unrelated to extracellular calcium.
Topics: Animals; Astrocytes; Calcium; Cells, Cultured; Cerebellum; Dihydropyridines; Dose-Response Relationship, Drug; Nimodipine; Nitrendipine; Rats; Rats, Inbred Strains; Taurine; Water-Electrolyte Balance | 1995 |
PCA 50941, a novel Ca2+ channel agonist.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium Channel Agonists; Cardiovascular System; Dihydropyridines; Heart Atria; In Vitro Techniques; Isradipine; Mesenteric Arteries; Muscles; Nitrendipine; Rabbits; Rats; Rats, Sprague-Dawley; Swine; Thiazoles; Vasoconstriction | 1993 |
Ruthenium red inhibits selectively chromaffin cell calcium channels.
Topics: Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Dihydropyridines; Enterochromaffin Cells; Iodine Radioisotopes; Nitrendipine; Norepinephrine; omega-Conotoxin GVIA; Peptides; Ruthenium Red; Tritium | 1994 |
Omega 3 polyunsaturated fatty acid modulates dihydropyridine effects on L-type Ca2+ channels, cytosolic Ca2+, and contraction in adult rat cardiac myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arachidonic Acid; Calcium; Calcium Channels; Dihydropyridines; Docosahexaenoic Acids; Fatty Acids, Omega-3; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardial Contraction; Nitrendipine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1994 |
Identification of dihydropyridine (DHP) binding sites on cultured monkey renal cells (GMRC) with a photoaffinity probe (-)-[3H]-azidopine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Azides; Binding Sites; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chlorocebus aethiops; Dihydropyridines; Kidney; Kinetics; Muscle Proteins; Nisoldipine; Nitrendipine; Propanolamines; Receptors, Adrenergic, beta | 1994 |
Boar sperm plasma membrane Ca(2+)-selective channels in planar lipid bilayers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cell Membrane; Dihydropyridines; Electrophysiology; Lipid Bilayers; Male; Nitrendipine; Spermatozoa; Stereoisomerism; Swine | 1995 |
Quinidine-induced potentiation of cardiovascular effects of nitrendipine: functional aspects and possible molecular mechanisms.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cardiovascular System; Dihydropyridines; Drug Synergism; Female; Guinea Pigs; Heart Atria; Hemodynamics; In Vitro Techniques; Male; Mesenteric Arteries; Nitrendipine; Quinine | 1995 |
Binding properties of (+/-)[3H]benidipine hydrochloride to rat heart membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Male; Membranes; Myocardium; Nitrendipine; Rats; Rats, Wistar | 1993 |
[Edema-inducing properties of lacidipine, nitrendipine and nifedipine in the spontaneously hypertensive rat].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Edema; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR; Serum Albumin | 1994 |
Pharmacological profile of UK-74,505, a novel and selective PAF antagonist with potent and prolonged oral activity.
Topics: Administration, Oral; Animals; Aorta; Azepines; Blood Platelets; Brain; Calcium Channels, L-Type; Capillary Permeability; Cattle; Dihydropyridines; Diltiazem; Gallopamil; Guinea Pigs; Hypotension; Imidazoles; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle Proteins; Nitrendipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium Chloride; Rabbits; Rats; Rats, Sprague-Dawley; Skin; Triazoles; Tritium | 1994 |
Hepatic Ito cells contain calcium channels: increases with transforming growth factor-beta 1.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Choline; Cytosol; Dihydropyridines; Extracellular Space; Female; Liver; Nitrendipine; Potassium; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Up-Regulation | 1994 |
Effects of oxodipine and nitrendipine on the size of experimental myocardial infarct in the rat.
Topics: Administration, Oral; Animals; Calcium Channel Blockers; Dihydropyridines; Female; Heart; Isoproterenol; Mitochondria, Heart; Myocardial Infarction; Myocardium; Nitrendipine; Random Allocation; Rats; Rats, Sprague-Dawley | 1994 |
Dihydropyridine ligands influence the evoked release of oxytocin and vasopressin dependent on stimulation conditions.
Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Electric Stimulation; Electrophysiology; Female; Ligands; Nicotinic Acids; Nitrendipine; Oxadiazoles; Oxytocin; Pituitary Gland, Posterior; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Vasopressins | 1994 |
Specific inhibition of Ca-activated K channels in red cells by selected dihydropyridine derivatives.
Topics: Calcium; Dihydropyridines; Erythrocytes; Humans; Nitrendipine; Potassium Channel Blockers; Potassium Channels | 1994 |
Erythrocyte membrane calcium transport in patients with primary hyperparathyroidism.
Topics: Biological Transport; Ca(2+) Mg(2+)-ATPase; Calcium; Dihydropyridines; Erythrocyte Membrane; Female; Humans; Hyperparathyroidism; Male; Middle Aged; Nitrendipine; Strontium | 1994 |
Blockers of Ca2+ channels in the plasmalemma of perfused Characeae cells.
Topics: Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chlorophyta; Dihydropyridines; Membrane Potentials; Nifedipine; Nitrendipine; Perfusion; Pyridines | 1994 |
Dihydropyridine ligand binding decreases earlier in adolescent than in infant swine after global cerebral ischemia.
Topics: Aging; Animals; Blood Pressure; Brain Ischemia; Calcium Channels; Caudate Nucleus; Cerebral Cortex; Dihydropyridines; Hippocampus; Isradipine; Ligands; Membrane Proteins; Nitrendipine; Protein Binding; Swine; Synaptosomes; Time Factors | 1994 |
P-glycoprotein-mediated transcellular transport of MDR-reversing agents.
Topics: Alkaloids; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Cell Line; Cell Line, Transformed; Dihydropyridines; Diltiazem; Drug Resistance; Epithelium; Humans; Kinetics; Membrane Glycoproteins; Nitrendipine; Protein Kinase C; Staurosporine; Sucrose; Transfection; Tritium | 1993 |
Radioautographic study of benidipine hydrochloride. Localization in the mesenteric artery of spontaneously hypertensive rat.
Topics: Animals; Autoradiography; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; In Vitro Techniques; Injections, Intravenous; Male; Mesenteric Arteries; Microscopy, Electron; Nitrendipine; Rats; Rats, Inbred SHR; Tissue Fixation | 1994 |
Dihydropyridine-sensitive calcium channels and barbiturate tolerance and withdrawal.
Topics: Anesthesia, General; Animals; Ataxia; Barbiturates; Bicuculline; Calcium Channels; Carbolines; Dihydropyridines; Drug Tolerance; Male; Mice; Mice, Inbred Strains; Nitrendipine; Pentobarbital; Seizures; Substance Withdrawal Syndrome | 1994 |
A new approach to separation of voltage-activated Ca currents in rat melanotrophs.
Topics: Animals; Calcium Channels; Dihydropyridines; Electric Conductivity; Electric Stimulation; Male; Melanocyte-Stimulating Hormones; Nicardipine; Nitrendipine; Pituitary Gland; Rats; Rats, Wistar | 1993 |
[Pharmacological profile of F-0401, a novel dihydropyridine derivative. (1) Mechanisms of action].
Topics: Animals; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Dihydropyridines; Guinea Pigs; Heart; In Vitro Techniques; Male; Muscle Contraction; Nitrendipine; Phosphodiesterase Inhibitors; Phospholipases A; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Thromboxane-A Synthase; Vasodilator Agents | 1993 |
Imaging terminals of Aplysia sensory neurons demonstrates role of enhanced Ca2+ influx in presynaptic facilitation.
Topics: Action Potentials; Animals; Aplysia; Calcium; Calcium Channels; Dihydropyridines; Motor Neurons; Neuronal Plasticity; Neurons, Afferent; Nitrendipine; Potassium Channels; Serotonin; Synapses | 1993 |
Calciseptine binding to a 1,4-dihydropyridine recognition site of the L-type calcium channel of rat synaptosomal membranes.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Cell Fractionation; Dihydropyridines; Diltiazem; Elapid Venoms; Intracellular Membranes; Kinetics; Ligands; Male; Nitrendipine; omega-Conotoxins; Peptides; Rats; Rats, Wistar; Synaptosomes; Verapamil | 1993 |
Ca2+ channel blocking activity of lacidipine and amlodipine in A7r5 vascular smooth muscle cells.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cytosol; Dihydropyridines; Female; Fura-2; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium Chloride; Pregnancy; Rats; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1993 |
Characterization of the type of calcium channel primarily regulating GABA exocytosis from brain nerve endings.
Topics: Animals; Brain; Cadmium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Exocytosis; gamma-Aminobutyric Acid; Male; Mice; Mollusk Venoms; Nerve Endings; Nickel; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxins; Peptides; Spider Venoms | 1995 |
Actions of 1,4-dihydropyridines in isolated mesenteric vascular beds.
Topics: Animals; Arginine; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Arteries; Nifedipine; Nitrendipine; Nitric Oxide; Nitroarginine; Vasodilation | 1995 |
Enantiomer separation of dihydropyridine calcium antagonists with cyclodextrins as chiral selectors: structural correlation.
Topics: Amlodipine; Buffers; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cyclodextrins; Dihydropyridines; Electrolytes; Electrophoresis, Capillary; Isradipine; Microspheres; Molecular Conformation; Nimodipine; Nisoldipine; Nitrendipine; Sodium Dodecyl Sulfate; Solvents; Stereoisomerism; Surface-Active Agents | 1996 |
Dihydropyridine-sensitive and -insensitive voltage-operated calcium channels participate in the control of glucose-induced insulin release from human pancreatic beta cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Mollusk Venoms; Nitrendipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides | 1996 |
Haemodynamic effects of lercanidipine in anaesthetized open-chest dogs.
Topics: Anesthesia; Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Injections, Intravenous; Male; Nitrendipine; Time Factors | 1996 |
Radioligand binding studies on some dihydropyridine analogues as probes of the dihydropyridine receptor.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cerebral Cortex; Dihydropyridines; Dogs; In Vitro Techniques; Male; Models, Biological; Nerve Tissue Proteins; Nitrendipine; Radioligand Assay; Structure-Activity Relationship | 1996 |
Effect of the new calcium antagonist lercanidipine and its enantiomers on the migration and proliferation of arterial myocytes.
Topics: Animals; Aorta; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Division; Cell Movement; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Male; Muscle, Smooth, Vascular; Nitrendipine; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1996 |
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Felodipine; Fumarates; Heart; Iron; Lipid Peroxidation; Male; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Verapamil | 1996 |
Differential effects of a K+ channel agonist and Ca2+ antagonists on myosin light chain phosphorylation in relaxation of endothelin-1-contracted tracheal smooth muscle.
Topics: Animals; Benzopyrans; Dihydropyridines; Endothelin-1; Muscle Relaxation; Muscle, Smooth; Myosin Light Chains; Nitrendipine; Sheep; Trachea; Verapamil | 1997 |
L-type calcium channels: binding domains for dihydropyridines and benzothiazepines are located in close proximity to each other.
Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Fluorescent Dyes; Isomerism; Isradipine; Kinetics; Nicotinic Acids; Nifedipine; Nitrendipine; Oxadiazoles; Rabbits | 1997 |
[Antihypertensive effects of a novel calcium antagonist, AE0047, in various hypertensive models].
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Hypertension, Renal; Injections, Intravenous; Nicardipine; Nitrendipine; Rats; Rats, Inbred SHR | 1997 |
Nimodipine and nitrendipine inhibit N-type calcium channels in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid (NG 108-15) cells.
Topics: Animals; Bucladesine; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Dihydropyridines; Evoked Potentials; Glioma; Hybrid Cells; Kinetics; Mice; Neuroblastoma; Nimodipine; Nitrendipine; Potassium; Rats | 1997 |
Chemical modification of the dihydropyridines binding sites by lysine reagent, pyridoxal 5'-phosphate.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Dihydropyridines; Indicators and Reagents; Kinetics; Lysine; Nitrendipine; Pyridoxal Phosphate; Rabbits | 1998 |
Calcium channel blocking and vasodilating actions of the novel dihydropyridine derivative AE0047.
Topics: Animals; Antihypertensive Agents; Aorta; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Cattle; Dihydropyridines; Dose-Response Relationship, Drug; Guinea Pigs; Heart Ventricles; Nicardipine; Nitrendipine; Patch-Clamp Techniques; Rats; Structure-Activity Relationship; Vasodilator Agents | 1998 |
Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Calcium Channel Blockers; CHO Cells; Cricetinae; Cytotoxins; Dihydropyridines; Drug Resistance, Multiple; Fibroblasts; Nicardipine; Nimodipine; Nitrendipine; Protein Binding; Verapamil; Vinblastine | 1998 |
Combinatorial synthesis and screening of a chemical library of 1,4-dihydropyridine calcium channel blockers.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Dihydropyridines; Drug Evaluation, Preclinical; In Vitro Techniques; Nitrendipine; Radioligand Assay; Rats | 1998 |
Single-cell RT-PCR and functional characterization of Ca2+ channels in motoneurons of the rat facial nucleus.
Topics: Animals; Animals, Newborn; Brain Stem; Cadmium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Dihydropyridines; DNA, Complementary; Facial Nerve; Ion Channel Gating; Motor Neurons; Nickel; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Rats; Rats, Wistar; Receptors, Cholinergic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spider Venoms | 1998 |
Functional interaction between benzothiazepine- and dihydropyridine binding sites of cardiac L-type Ca2+ channels.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cell Line; Dihydropyridines; Diltiazem; Membrane Potentials; Myocardium; Nitrendipine; Patch-Clamp Techniques; Temperature; Thiazepines; Time Factors | 1998 |
The new calcium antagonist lercanidipine and its enantiomers affect major processes of atherogenesis in vitro: is calcium entry involved?
Topics: Animals; Antihypertensive Agents; Arteriosclerosis; Brain; Calcium Channel Blockers; Cell Division; Dihydropyridines; In Vitro Techniques; Male; Membranes; Muscle, Smooth, Vascular; Nitrendipine; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1998 |
Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Dihydropyridines; Fluorescent Dyes; Fluorometry; Fura-2; Intracellular Fluid; Nitrendipine; Nitrobenzenes; Patch-Clamp Techniques; Piperazines; Potassium; Rats; Stereoisomerism | 1999 |
Effects of prolonged exposure to ethanol in vivo on functional parameters and sensitivity to nitrendipine in the isolated rat heart.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Drug Interactions; Ethanol; Heart; Male; Myocardium; Nitrendipine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1999 |
Dihydropyridine and beta adrenergic receptor binding in dogs with tachycardia-induced atrial fibrillation.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Atrial Fibrillation; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Cardiac Pacing, Artificial; Dihydropyridines; Dogs; Female; Iodocyanopindolol; Linear Models; Male; Myocardium; Nitrendipine; Receptors, Adrenergic, beta; Sarcolemma; Statistics, Nonparametric | 1999 |
Damaging effects of the calcium paradox are reduced in isolated hearts from ethanol-dependent rats: paradoxic effects of dihydropyridine drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alcoholism; Animals; Calcium; Calcium Channel Blockers; Central Nervous System Depressants; Dihydropyridines; Ethanol; Heart; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardium; Nitrendipine; Perfusion; Rats; Rats, Sprague-Dawley | 1999 |
Calcium channel activation and self-biting in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior | 1999 |
Dihydropyridine-induced Ca2+ release from ryanodine-sensitive Ca2+ pools in human skeletal muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Humans; Muscle, Skeletal; Nifedipine; Nitrendipine; PC12 Cells; Protein Conformation; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel | 2000 |
Comparison of effects of nitrendipine, lacidipine and mibefradil on postischaemic myocardial damage in isolated rat hearts.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Female; Heart; Hemodynamics; In Vitro Techniques; Male; Mibefradil; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitrendipine; Pressure; Rats; Rats, Wistar; Reference Values; Ventricular Function, Left | 2000 |
Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Chloride Channels; Dihydropyridines; Drug Interactions; Glycine; Neural Inhibition; Neurons; Nicardipine; Nifedipine; Nitrendipine; Rats; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Synaptic Transmission; Verapamil | 2001 |
Therapeutic effects of DCDDP, a calcium channel blocker, on chronic pulmonary hypertension in rat.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Division; Cells, Cultured; Chronic Disease; Dicarboxylic Acids; Dihydropyridines; Endothelins; Hemodynamics; Hypertension, Pulmonary; Male; Malondialdehyde; Monocrotaline; Muscle, Smooth, Vascular; Nitrendipine; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Serotonin; Superoxide Dismutase; Vasoconstriction | 2002 |
Independent modulation of L-type Ca2+ channel in guinea pig ventricular cells by nitrendipine and isoproterenol.
Topics: Adrenergic beta-Agonists; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Colforsin; Dihydropyridines; Electrophysiology; Evoked Potentials; Guinea Pigs; Heart Ventricles; Isoproterenol; Nitrendipine; Patch-Clamp Techniques; Phosphorylation | 2001 |
Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Colforsin; Cyclic AMP; Dihydropyridines; Electrophysiology; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Ion Channels; Isoproterenol; Manganese; Membrane Potentials; Myocardium; Myocytes, Cardiac; Nitrendipine; Patch-Clamp Techniques; Rabbits; Signal Transduction | 2003 |
[Most hypertensive patients need drug combination treatment. "First line therapy is in second place"].
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Drug Therapy, Combination; Humans; Hypertension; Nitrendipine | 2003 |
Inhibition of type A GABA receptors by L-type calcium channel blockers.
Topics: 4-Butyrolactone; Animals; Benzodiazepines; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Humans; Hypothalamus; Kidney; Mutagenesis, Site-Directed; Nitrendipine; Picrotoxin; Protein Structure, Tertiary; Rats; Receptors, GABA-A; Recombinant Proteins; Solvents; Species Specificity; Zinc | 2004 |
BCRP transports dipyridamole and is inhibited by calcium channel blockers.
Topics: Algorithms; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport, Active; Calcium Channel Blockers; Cell Line; Cell Survival; Dihydropyridines; Dipyridamole; Dogs; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Humans; Immunoblotting; Microscopy, Confocal; Mitoxantrone; Neoplasm Proteins; Nitrendipine; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley | 2005 |
Azelnidipine, a dihydropyridine-based calcium antagonist, inhibits angiotensin II-induced oxidative stress generation and downregulation of pigment epithelium-derived factor mRNA levels in microvascular endothelial cells.
Topics: Angiotensin II; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Endothelial Cells; Eye Proteins; Gene Expression Regulation; Humans; Microcirculation; Nerve Growth Factors; Nitrendipine; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Serpins | 2005 |
T-type Ca2+ channel blockade prevents sudden death in mice with heart failure.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cardiomyopathy, Dilated; Death, Sudden, Cardiac; Dihydropyridines; Disease Models, Animal; Female; Mibefradil; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Infarction; Myocytes, Cardiac; Nitrendipine; Nitrophenols; Organophosphorus Compounds; Patch-Clamp Techniques | 2009 |
Ca(2+) channel blocker benidipine promotes coronary angiogenesis and reduces both left-ventricular diastolic stiffness and mortality in hypertensive rats.
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Coronary Circulation; Diastole; Dihydropyridines; Heart Failure; Heart Ventricles; Hypertension; Male; Neovascularization, Physiologic; Nitrendipine; Rats; Rats, Inbred Dahl | 2010 |
Influence of dihydropyridine calcium antagonist nitrendipine on benzo(a)pyrene-induced oxidative stress.
Topics: Animals; Antioxidants; Aspartate Aminotransferases; Benzo(a)pyrene; Brain; Calcium Channel Blockers; Dihydropyridines; Glutathione; Hazardous Substances; Liver; Liver Function Tests; Lung; Male; Nitrendipine; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2011 |
Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine.
Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Dihydropyridines; Heart; Hemodynamics; Male; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2012 |
Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonomic Nervous System; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cardiomyopathy, Dilated; Death, Sudden, Cardiac; Dihydropyridines; Disease Models, Animal; Heart; Heart Failure; Mice, Knockout; Mice, Transgenic; Nitrendipine; Repressor Proteins; Time Factors; Ventricular Function, Left | 2014 |
In search of the mutual relationship between the structure, solid-state spectroscopy and molecular dynamics in selected calcium channel blockers.
Topics: Calcium Channel Blockers; Crystallization; Dihydropyridines; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Nifedipine; Nimodipine; Nitrendipine; Quantum Theory; Spectrophotometry, Infrared; X-Ray Diffraction | 2016 |