nitrendipine has been researched along with bay-k-8644 in 180 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 98 (54.44) | 18.7374 |
| 1990's | 69 (38.33) | 18.2507 |
| 2000's | 11 (6.11) | 29.6817 |
| 2010's | 2 (1.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lipscombe, D; Xu, W | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Cuddon, P; Fleming, A; Floto, RA; Goldsmith, P; Jahreiss, L; O'Kane, CJ; Pask, D; Rubinsztein, DC; Saiki, S; Sarkar, S; Siddiqi, FH; Ttofi, EK; Williams, A | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Baumgarten, L; Villereal, M | 1 |
| Gandhi, VC; Jones, DJ | 2 |
| Diederichs, W; Graff, J; Sroka, J | 1 |
| Hallaq, H; Leaf, A; Smith, TW | 1 |
| Hijioka, T; Lemasters, JJ; Rosenberg, RL; Thurman, RG | 1 |
| Baumgarten, LB; Toscas, K; Villereal, ML | 1 |
| Hom, GJ; Rubanyi, GM; Touhey, B | 1 |
| Babcock, DF; Corron, ME; Florman, HM; Kim, TD | 1 |
| Zatz, M | 2 |
| Kennedy, RH; Ruch, S; Seifen, E | 1 |
| Alonso, R; Boksa, P; Chaudieu, I; Mount, H; Quirion, R | 1 |
| Little, HJ; Littleton, JM; Whittington, MA | 1 |
| Battaini, F; Bergamaschi, S; Govoni, S; Meucci, O; Parenti, M; Schettini, G; Trabucchi, M | 1 |
| Birkenhäger, JC; Buurman, CJ; Pols, HA; Schilte, JP; van Leeuwen, JP | 1 |
| Carroll, BL; Crowley, WR; Dockter, ME; Kalra, SP; Kennedy, D; Shah, GV | 1 |
| Frank, GB | 1 |
| Kasper, G; Marquez, CR; Zatz, M | 1 |
| Bolger, GT; O'Neill, SK; Triggle, CR | 2 |
| Baydoun, AR; Markham, A; Morgan, RM; Sweetman, AJ | 1 |
| Ballesta, JJ; Garcia, AG; Gutierrez, LM; Hidalgo, MJ; Palmero, M; Reig, JA; Viniegra, S | 1 |
| Fox, AP; Hirning, LD; Miller, RJ | 1 |
| Biguad, M; Julou-Schaeffer, G; Parratt, JR; Stoclet, JC | 1 |
| Regan, LJ | 1 |
| Kolchinskaya, LI; Kononenko, NI; Pogorelaya, NC | 1 |
| Dolin, SJ; Little, HJ; Patch, TL; Rabbani, M; Taberner, PV | 1 |
| de Pascual, R; Gandía, L; García, AG; López, MG; Michelena, P | 1 |
| Barrett, PQ; Bollag, WB; Isales, CM; McCarthy, RT | 1 |
| Black, IB; DiCicco-Bloom, E; Pincus, DW | 1 |
| Camilión de Hurtado, MC; Cingolani, HE; Gende, OA | 1 |
| Akimoto, T; Ariyoshi, S; Fujisue, T; Ichida, S; Wada, T | 1 |
| Bondar', VS; Rozhmanova, OM; Voronina, SG; Vysotskiĭ, ES | 1 |
| Adeagbo, AS; Triggle, CR | 1 |
| Baik, YH; Dube, GP; Schwartz, A; Vaghy, PL | 1 |
| Langer, SZ; Schoemaker, H | 1 |
| Kojima, I; Kojima, K; Rasmussen, H | 3 |
| Bean, BP | 1 |
| Carpenter, CL; Cooper, EC; Greenberg, DA | 2 |
| Gopalakrishnan, V; Park, LE; Triggle, CR | 1 |
| Dillon, JS; Elz, JS; McKelvie, M; Nayler, WG | 1 |
| Forder, J; Rasmussen, H; Scriabine, A | 1 |
| Criscione, L; Meier, M; Rogg, H; Truog, A | 1 |
| Carboni, E; Costa, E; Wojcik, WJ | 1 |
| Borosky, SA; Cooper, CW; Farrell, PE; Steinsland, OS | 1 |
| Harris, KM; Kongsamut, S; Miller, RJ | 1 |
| Kongsamut, S; Miller, RJ | 1 |
| Hock, CE; Lefer, AM; Whitney, CC | 1 |
| Garcia, ML; Kaczorowski, GJ; King, VF; Reuben, JP; Siegl, PK | 1 |
| Catt, KJ; Chang, JP; Graeter, J; McCoy, EE; Tasaka, K | 1 |
| Bean, BP; Hermsmeyer, K; Puga, A; Sturek, M | 1 |
| Carpenter, CL; Greenberg, DA; Messing, RO | 1 |
| Luchowski, EM; Rutledge, A; Su, CM; Triggle, DJ; Wei, XY | 1 |
| Chernow, B; Ives, N; King, JW; Roth, BL | 1 |
| Aunis, D; Gandía, L; García, AG; Ladona, MG | 1 |
| Hosey, MM; Maan, AC; Ptasienski, J | 1 |
| Cornwell, MM; Gottesman, MM; Pastan, I | 1 |
| Bedard, RM; Busse, WW; Swenson, CA | 1 |
| Freed, WJ; Grebb, JA; Shelton, RC | 1 |
| Brown, AM; Kunze, DL; Yatani, A | 2 |
| Brown, AM; Brush, K; Hamilton, SL; Schwartz, A; Yatani, A | 1 |
| Rampe, D; Triggle, DJ | 1 |
| Janis, RA; Sarmiento, JG; Shrikhande, AV; Triggle, DJ | 1 |
| Skattebøl, A; Triggle, DJ | 1 |
| Bräutigam, M; Herken, H; Kittner, B | 1 |
| Brennan, CH; Charles, S; Hudspith, MJ; Littleton, JM | 1 |
| Finkel, MS; Tallman, JF | 1 |
| Challoner-Hue, L; Steele, TH | 2 |
| Miwa, K; Schwartz, A | 1 |
| Crankshaw, J; Daniel, EE; Kyozuka, M | 1 |
| Bechem, M; Metzger, G; Schramm, M; Thomas, G | 1 |
| DeRoth, L; Godfraind, T; Wibo, M | 1 |
| Harper, JC; Littleton, JM; Pagonis, C | 1 |
| Crankshaw, DJ; Ruzycky, AL; Triggle, DJ | 1 |
| Litten, RZ; Roth, BL; Suba, EA | 1 |
| Bolger, GT; Weissman, BA | 1 |
| Carboni, E; Wojcik, WJ | 1 |
| Oswald, RE; Simasko, SM; Weiland, GA | 1 |
| Matsunaga, H; Ogata, E; Shibuya, N; Takakura, K; Teramoto, A; Yamashita, N | 1 |
| Gallant, S; Gengo, P; Hawthorn, MH; Moran, JF; Rutledge, A; Triggle, DJ; Wei, XY | 1 |
| Jia, M; Litzinger, M; Nelson, PG; Yu, C | 1 |
| Massieu, L; Tapia, R | 1 |
| Dunn, SM | 2 |
| Mullen, DA; Zatz, M | 1 |
| Bihoreau, C; Clauser, H; Drouva, SV; Kordon, C; Laplante, E; Rasolonjanahary, R; Rerat, E | 1 |
| Dolin, SJ; Halsey, MJ; Hunter, AB; Little, HJ | 1 |
| Cooper, CW; Seitz, PK; Yi, SJ | 1 |
| Andriantsitohaina, R; Stoclet, JC | 1 |
| Borea, PA; Caparrotta, L; De Biasi, M; Fassina, G; Froldi, G; Pandolfo, L; Ragazzi, E | 1 |
| Boarder, MR; Owen, PJ; Plevin, R | 1 |
| January, CT; Riddle, JM | 1 |
| Fry, HK; McCarthy, RT | 1 |
| Basile, AS; Bolger, GT; Lueddens, HW; Newman, AH; Rice, KC; Skolnick, P | 1 |
| Cooper, CW; Seitz, PK | 1 |
| Kashiwabara, T; Nakayama, K; Tanaka, Y; Yamada, S | 1 |
| Prives, J; Rapuano, M; Ross, AF | 1 |
| Kazda, S; Stasch, JP | 1 |
| Donowitz, M; Homaidan, FR; Sharp, GW; Weiland, GA | 1 |
| Fujisue, T; Ichida, S; Masada, A; Matsuda, N; Yoshioka, T | 1 |
| Bose, D; Bouchard, RA; Chau, T; Hryshko, LV; Saha, JK | 1 |
| Felbel, J; Hofmann, F; Peper, K; Welling, A | 1 |
| Baro, I; Coraboeuf, E; Coulombe, A; Lefèvre, IA | 1 |
| Brennan, CH; Harper, JC; Littleton, JM | 1 |
| Brennan, CH; Lewis, A; Littleton, JM | 1 |
| Baró, I; Escande, D | 1 |
| Belin, C; Carriot, T; Doble, A; Dubroeucq, MC; Guérémy, C; Le Fur, G; Mestre, M; Renault, C; Uzan, A | 1 |
| Marban, E; Wier, WG | 1 |
| Chung, M; Cohen, CJ; Thomas, G | 1 |
| Freedman, SB; Kongsamut, S; Miller, RJ | 1 |
| Bolger, GT; Skolnick, P; Weissman, BA | 1 |
| Fischli, W; Hengartner, U; Holck, M | 1 |
| Bellemann, P | 1 |
| Groth, H; Locher, R; Neyses, L; Stimpel, M; Vetter, W | 1 |
| Albus, U; Ferry, DR; Glossmann, H; Habermann, E | 1 |
| Janis, RA; Rampe, D; Sarmiento, JG; Triggle, DJ | 1 |
| Freedman, SB; Miller, DM; Miller, RJ; Tindall, DR | 1 |
| Freedman, SB; Miller, RJ | 1 |
| Grupp, G; Grupp, IL; Schwartz, A; Vaghy, PL | 1 |
| Balwierczak, JL; Grupp, G; Grupp, IL; Schwartz, A; Vaghy, PL; Williams, JS | 1 |
| Adelstein, RS; Movsesian, MA | 1 |
| Janis, RA; Rampe, D; Triggle, DJ | 1 |
| Bolger, GT; Janis, RA; Maurer, SC; Sarmiento, JG; Triggle, DJ | 1 |
| Grupp, G; Grupp, IL; Schwartz, A; Vaghy, PL; Williams, JS | 1 |
| Brochu, M; Roy, B; Sicotte, B; St-Louis, J | 1 |
| Artalejo, CR; Cillero, FJ; de Casa-Juana, MF; de Pascual, R; García, AG; González-Morales, MA; López, MG; Priego, J; Sunkel, C; Villarroya, M | 1 |
| Bouhtiauy, I; Brunette, MG; Lajeunesse, D | 1 |
| Bogdanov, K; Hallaq, H; Lakatta, E; Leaf, A; Pepe, S; Spurgeon, H | 1 |
| Cross, AJ; Green, AR; Little, HJ; Misra, A; Watson, WP | 1 |
| Bauriedel, G; Heimerl, J; Höfling, B; Kruse, HJ; Weber, PC | 1 |
| Drímal, J | 1 |
| Little, HJ; Watson, WP | 1 |
| Frank, GB; Oz, M | 1 |
| Filloux, FM; Fitts, RC; Skeen, GA; White, HS | 1 |
| Kamp, TJ; Marbán, E; Pérez-García, MT | 1 |
| Cox, TC; Tiwari-Woodruff, SK | 1 |
| García, AG; Guantes, JM; Michelena, P; Montiel, C; Uceda, G | 1 |
| Ballerini, P; Caciagli, F; Ciccarelli, R; Di Iorio, P; Giuliani, P | 1 |
| Akimoto, T; Ichida, S; Kishino, H; Matsuda, N; Nakazaki, S; Wada, T | 1 |
| Goto, M; Hijioka, T; Lemasters, JJ; Thurman, RG | 1 |
| Gairard, A; Stoclet, JC; Van Overloop, B | 1 |
| Damaj, MI; Martin, BR; Welch, SP | 1 |
| Caviedes, P; Caviedes, R; Jaimovich, E; Olivares, E; Salas, K | 1 |
| Szabó, C; Thiemermann, C; Vane, JR | 1 |
| Borges, R | 1 |
| Biancardi, E; Carbone, E; Clementi, F; Davalli, AM; Pollo, A; Pontiroli, AE; Pozza, G; Sher, E; Socci, C | 1 |
| Gasser, PJ; Gern, WA | 1 |
| Damaj, MI | 1 |
| Marley, PD; O'Farrell, M; Ziogas, J | 1 |
| Ma, L; Patterson, E; Robinson, CP; Szabo, B; Thadani, U | 1 |
| Koizumi, S; Moriyama, Y; Ogura, A; Yamada, H; Yamaguchi, A | 1 |
| Mironov, SL; Richter, DW | 1 |
| Ban, Y; Makita, T | 1 |
| Hadziselimovic, R; Hukovic, N | 1 |
| Campbell, DB; Hess, EJ | 1 |
| Iuvone, PM; Uchida, K | 1 |
| Marley, PD; O'Farrell, M | 1 |
| Guppy, LJ; Littleton, JM | 1 |
| Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S | 1 |
| Bilbaut, A; Dupré-Aucouturier, S; Guyot, A; Ojeda, C; Rougier, O | 1 |
| Brochu, M; Picard, S; Simaan, M; St-Louis, J | 1 |
| Hohenegger, M; Kress, HG; Weigl, LG | 1 |
| Cathala, L; Chesnoy-Marchais, D | 1 |
| Galston, AW; Migliaccio, F | 1 |
| Bollag, WB; Calle, RA; Jung, E | 1 |
| Hino, N; Masumiya, H; Ochi, R; Tsujikawa, H | 1 |
| Blanck, TJ; Montoya-Gacharna, J; Neubert, TA; Recio-Pinto, E; Sutachan, JJ; Xu, CF; Xu, F; Zhang, J | 1 |
| Jacobson, KA; Jiang, JL; Melman, N; Olah, ME; Stiles, GL; van Rhee, AM | 1 |
1 review(s) available for nitrendipine and bay-k-8644
| Article | Year |
|---|---|
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels | 2010 |
179 other study(ies) available for nitrendipine and bay-k-8644
| Article | Year |
|---|---|
Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alternative Splicing; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Kidney; Membrane Potentials; Molecular Sequence Data; Nimodipine; Oocytes; Patch-Clamp Techniques; Protein Subunits; Rats; Signal Transduction; Transfection; Xenopus | 2001 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Topics: Animals; Autophagy; Calcium Channels, L-Type; Clonidine; Cyclic AMP; Humans; Huntington Disease; Imidazoline Receptors; Minoxidil; Protein Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Type C Phospholipases; Verapamil | 2008 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Bradykinin stimulates Ca2+ entry via nitrendipine-sensitive Ca2+ channels in cultured human fibroblasts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Barium; Bradykinin; Calcium; Calcium Channels; Calcium Radioisotopes; Cells, Cultured; Fibroblasts; Humans; Kinetics; Male; Nitrendipine; Skin | 1992 |
Protein kinase C modulates the release of [3H]5-hydroxytryptamine in the spinal cord of the rat: the role of L-type voltage-dependent calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Calcium Channel Blockers; Calcium Channels; Enzyme Activation; In Vitro Techniques; Male; Nerve Tissue Proteins; Nitrendipine; omega-Conotoxins; Peptides, Cyclic; Potassium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Staurosporine; Synaptosomes; Tetradecanoylphorbol Acetate | 1992 |
Comparison of Bay K 8644, nitrendipine and atropine on spontaneous and pelvic-nerve-induced bladder contractions on rat bladder in vivo.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Female; Muscle Contraction; Muscle, Smooth; Nitrendipine; Rats; Urinary Bladder | 1992 |
Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cells, Cultured; Dihydropyridines; Fatty Acids, Unsaturated; Fish Oils; Heart; In Vitro Techniques; Ion Channel Gating; Myocardial Contraction; Nitrendipine; Ouabain; Rats; Verapamil | 1992 |
Kupffer cells contain voltage-dependent calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Drug Interactions; Female; Fura-2; Kupffer Cells; Membrane Potentials; Nitrendipine; Potassium; Rats; Rats, Inbred Strains | 1992 |
Dihydropyridine-sensitive L-type Ca2+ channels in human foreskin fibroblast cells. Characterization of activation with the growth factor Lys-bradykinin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channels; Cells, Cultured; Dihydropyridines; Fibroblasts; Fura-2; Humans; Ion Channel Gating; Kallidin; Nitrendipine | 1992 |
Effects of intracoronary administration of endothelin in anesthetized dogs: comparison with Bay k 8644 and U 46619.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Coronary Circulation; Coronary Vessels; Dogs; Endothelins; Female; Hemodynamics; Injections, Intra-Arterial; Male; Nitrendipine; Prostaglandin Endoperoxides, Synthetic | 1992 |
Activation of voltage-dependent calcium channels of mammalian sperm is required for zona pellucida-induced acrosomal exocytosis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acrosome; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cattle; Dihydropyridines; Exocytosis; Isradipine; Male; Mice; Nitrendipine; Sheep; Spermatozoa; Zona Pellucida | 1992 |
Agents that affect calcium influx can change cyclic nucleotide levels in cultured chick pineal cells.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Kinetics; Nitrendipine; Pineal Gland | 1992 |
Aging: inotropic effects of Bay K-8644 and nifedipine on rat cardiac muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Analysis of Variance; Animals; Calcium; Calcium Channels; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Rats; Rats, Inbred F344 | 1992 |
Effects of L- and N-type Ca2+ channel antagonists on excitatory amino acid-evoked dopamine release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Cells, Cultured; Dopamine; Kainic Acid; Mesencephalon; N-Methylaspartate; Nitrendipine; omega-Conotoxin GVIA; Peptides, Cyclic; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Veratridine | 1992 |
Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal; doses required, stereospecificity and actions of Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Ethanol; Isradipine; Male; Mice; Nimodipine; Nitrendipine; Oxadiazoles; Stereoisomerism; Substance Withdrawal Syndrome; Time Factors | 1990 |
Modulation of dihydropyridine-sensitive calcium channels: a role for G proteins.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Dihydropyridines; GTP-Binding Proteins; Guanosine Triphosphate; Isradipine; Neurons; Nitrendipine; Oxadiazoles; Rats; Tumor Cells, Cultured | 1990 |
Role of calcium and cAMP in heterologous up-regulation of the 1,25-dihydroxyvitamin D3 receptor in an osteoblast cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenine; Adenylyl Cyclase Inhibitors; Calcitriol; Calcium; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Nitrendipine; Osteoblasts; Parathyroid Hormone; Receptors, Calcitriol; Receptors, Steroid; Up-Regulation; Verapamil | 1990 |
Neuropeptide-Y enhances luteinizing hormone (LH)-releasing hormone-induced LH release and elevations in cytosolic Ca2+ in rat anterior pituitary cells: evidence for involvement of extracellular Ca2+ influx through voltage-sensitive channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cytosol; Egtazic Acid; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Neuropeptide Y; Nitrendipine; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains | 1990 |
Dihydropyridine calcium channel antagonists block and agonists potentiate high potassium contractures but not twitches in frog skeletal muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; In Vitro Techniques; Muscle Contraction; Nifedipine; Nitrendipine; Potassium; Pyridines; Rana pipiens | 1990 |
Vasoactive intestinal peptide stimulates chick pineal melatonin production and interacts with other stimulatory and inhibitory agents but does not show alpha 1-adrenergic potentiation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chickens; Colforsin; Drug Interactions; Isoproterenol; Kinetics; Light; Melatonin; Nitrendipine; Norepinephrine; Phenylephrine; Pineal Gland; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1990 |
Comparative studies with enantiomers of dihydropyridine ligands suggests that there are multiple binding sites associated with the calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain Chemistry; Calcium Channels; Dihydropyridines; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Ligands; Male; Mice; Muscle, Smooth; Myocardium; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Stereoisomerism | 1990 |
Bay K 8644, modifier of calcium transport and energy metabolism in rat heart mitochondria: a new intracellular site of action.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Diphosphate; Animals; Biological Transport, Active; Calcium; Diltiazem; Energy Metabolism; Female; Glutamates; In Vitro Techniques; Malates; Mitochondria, Heart; NAD; Nitrendipine; Oxidation-Reduction; Oxygen Consumption; Rats; Ruthenium Red; Verapamil | 1990 |
Separate [3H]-nitrendipine binding sites in mitochondria and plasma membranes of bovine adrenal medulla.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium Channels; Cattle; Cell Membrane; Chromaffin System; Diltiazem; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Mitochondria; Nitrendipine; Receptors, Nicotinic; Stereoisomerism; Subcellular Fractions; Verapamil | 1990 |
Inhibition of calcium currents in cultured myenteric neurons by neuropeptide Y: evidence for direct receptor/channel coupling.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cells, Cultured; Dihydropyridines; Fura-2; Membrane Potentials; Myenteric Plexus; Neurons; Neuropeptide Y; Nitrendipine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Neuropeptide Y; Receptors, Neurotransmitter; Virulence Factors, Bordetella | 1990 |
Endotoxin-induced impairment of vascular smooth muscle contractions elicited by different mechanisms.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Caffeine; Calcimycin; Calcium; Clonidine; Endothelium, Vascular; Endotoxins; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum | 1990 |
Voltage-dependent calcium currents in Purkinje cells from rat cerebellar vermis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Barium; Calcium Channels; Cell Separation; Dihydropyridines; Electric Conductivity; Electrophysiology; Nickel; Nimodipine; Nitrendipine; Purkinje Cells; Rats | 1991 |
Inhibition by oxytocin of voltage-activated calcium influx in cultured PC12 pheochromocytoma cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channels; Kinetics; Lithium; Membrane Potentials; Nitrendipine; Pheochromocytoma; Potassium; Rats; Second Messenger Systems; Tumor Cells, Cultured | 1991 |
Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthesia; Animals; Ataxia; Benzodiazepines; Brain; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Flurazepam; GABA-A Receptor Antagonists; Isoquinolines; Male; Mice; Midazolam; Nitrendipine; Seizures | 1991 |
Different sensitivities to dihydropyridines of catecholamine release from cat and ox adrenals.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Catecholamines; Cats; Cattle; Dihydropyridines; In Vitro Techniques; Isradipine; Male; Nitrendipine; Perfusion; Species Specificity | 1990 |
Ca2+ channels and aldosterone secretion: modulation by K+ and atrial natriuretic peptide.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aldosterone; Animals; Atrial Natriuretic Factor; Calcium; Calcium Channels; Cells, Cultured; Electrophysiology; Nitrendipine; Osmolar Concentration; Potassium; Zona Glomerulosa | 1991 |
Role of voltage-sensitive calcium channels in mitogenic stimulation of neuroblasts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Calcium Channel Blockers; Calcium Channels; Cell Division; Cells, Cultured; DNA Replication; Ganglia, Sympathetic; Insulin; Male; Models, Neurological; Neurons; Nitrendipine; Potassium Chloride; Rats; Rats, Inbred Strains; Tetrodotoxin; Thymidine; Vasoactive Intestinal Peptide; Veratridine | 1991 |
Bay K 8644 enhances the outflow of [3H]-noradrenaline and [3H]-DOPEG from isolated rat atria.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic Fibers; Animals; Calcium; Electric Stimulation; Female; Heart; Heart Atria; Heart Rate; Methoxyhydroxyphenylglycol; Myocardium; Nitrendipine; Norepinephrine; Rats; Rats, Inbred Strains | 1991 |
Effects of calcium channel agonists (BAY K 8644, CGP28392 and YC-170) on 45Ca uptake by rat uterine segments.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Female; Nifedipine; Nitrendipine; Potassium Chloride; Pyridines; Rats; Rats, Inbred Strains; Uterus | 1991 |
[The Ca2+-activated photoprotein obelin as a calcium transport inducer in proteoliposomes in the membrane of the T-system of skeletal muscles].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biological Transport; Calcium; Calcium Channels; Cell Membrane; Chromatography, Gel; Luminescent Proteins; Muscles; Nitrendipine; Rabbits | 1991 |
Effects of some inorganic divalent cations and protein kinase C inhibitors on endothelium-dependent relaxation in rat isolated aorta and mesenteric arteries.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Alkaloids; Animals; Aorta, Thoracic; Calcium; Cations, Divalent; Endothelium, Vascular; Histamine; In Vitro Techniques; Isoquinolines; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrendipine; Nitroprusside; Norepinephrine; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine | 1991 |
Nitrendipine potentiates Bay k 8644-induced contraction of isolated porcine coronary artery: evidence for functionally distinct dihydropyridine receptor subtypes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Coronary Vessels; Drug Synergism; In Vitro Techniques; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Receptors, Nicotinic; Swine | 1985 |
[3H]diltiazem binding to calcium channel antagonists recognition sites in rat cerebral cortex.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Calcium Channels; Cerebral Cortex; Diltiazem; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Tritium | 1985 |
Characteristics of angiotensin II-, K+- and ACTH-induced calcium influx in adrenal glomerulosa cells. Evidence that angiotensin II, K+, and ACTH may open a common calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Adrenocorticotropic Hormone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Cattle; In Vitro Techniques; Ion Channels; Kinetics; Nifedipine; Nitrendipine; Potassium | 1985 |
Role of calcium fluxes in the sustained phase of angiotensin II-mediated aldosterone secretion from adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Cattle; Dantrolene; In Vitro Techniques; Ion Channels; Kinetics; Models, Biological; Nifedipine; Nitrendipine; Potassium | 1985 |
Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Barium; Calcium; Cobalt; Dogs; Heart Atria; Ion Channels; Isoproterenol; Kinetics; Myocardium; Nifedipine; Nitrendipine; Tetrodotoxin | 1985 |
Stimulation of calcium uptake in PC12 cells by the dihydropyridine agonist BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Nifedipine; Nitrendipine; Pheochromocytoma; Pyridines; Rats | 1985 |
The effect of the calcium channel agonist, Bay K-8644 on human vascular smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Cell Membrane; Humans; In Vitro Techniques; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium; Serotonin; Umbilical Arteries | 1985 |
An effect of ischemia on myocardial dihydropyridine binding sites.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aerobiosis; Animals; Binding, Competitive; Calcium; Calcium Channels; Coronary Disease; In Vitro Techniques; Kinetics; Male; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Sarcolemma | 1985 |
Plasma membrane calcium flux, protein kinase C activation and smooth muscle contraction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cell Membrane; Colforsin; Drug Synergism; Enzyme Activation; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Ouabain; Perfusion; Phospholipids; Potassium; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Vasoconstriction | 1985 |
In vitro comparative studies of the calcium-entry activators YC-170, CGP 28392, and BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Biological Transport; Calcium; Guinea Pigs; Heart Rate; In Vitro Techniques; Ion Channels; Male; Mesentery; Myocardial Contraction; Nifedipine; Nitrendipine; Pyridines; Rats; Vasoconstriction | 1985 |
Dihydropyridines change the uptake of calcium induced by depolarization into primary cultures of cerebellar granule cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cells, Cultured; Cerebellum; Ion Channels; Nifedipine; Nitrendipine; Potassium Chloride; Rats; Veratridine | 1985 |
Effects of the calcium channel activator BAY-K-8644 on in vitro secretion of calcitonin and parathyroid hormone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcitonin; Calcium; Culture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Nifedipine; Nitrendipine; Parathyroid Glands; Parathyroid Hormone; Rats; Thyroid Gland | 1986 |
Protein kinase C mediated regulation of calcium channels in PC-12 pheochromocytoma cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Calcium; Cells, Cultured; Humans; Ion Channels; Nifedipine; Nitrendipine; Norepinephrine; Pheochromocytoma; Phorbol Esters; Protein Kinase C; Synaptic Transmission; Tetradecanoylphorbol Acetate | 1986 |
Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bucladesine; Calcium; Cell Differentiation; Dihydropyridines; Nerve Growth Factors; Nifedipine; Nitrendipine; Norepinephrine; Pheochromocytoma; Potassium; Pyridines; Rats; Secretory Rate | 1986 |
Mechanism of the pressor effect of the calcium agonist, BAY k 8644, in the intact rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetophenones; Animals; Arginine Vasopressin; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Catecholamines; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydrazines; Male; Nifedipine; Nisoldipine; Nitrendipine; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Saralasin; Tetrazoles | 1986 |
Binding of Ca2+ entry blockers to cardiac sarcolemmal membrane vesicles. Characterization of diltiazem-binding sites and their interaction with dihydropyridine and aralkylamine receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Diltiazem; Dithiothreitol; Ethylmaleimide; Female; Guinea Pigs; Hydrogen-Ion Concentration; Iodocyanopindolol; Male; Myocardium; Nifedipine; Nitrendipine; Ouabain; Pindolol; Receptors, Nicotinic; Sodium; Sodium-Potassium-Exchanging ATPase; Stereoisomerism; Temperature; Verapamil | 1986 |
Participation of voltage-dependent calcium channels in the action of gonadotropin-releasing hormone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Calcimycin; Calcium; Cells, Cultured; Cytoplasm; Ethers; Female; Fluorescent Dyes; Gonadotropin-Releasing Hormone; Ion Channels; Ionomycin; Luteinizing Hormone; Nifedipine; Nitrendipine; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains | 1986 |
Calcium channels in muscle cells isolated from rat mesenteric arteries: modulation by dihydropyridine drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Pyridines; Rats | 1986 |
Depolarization-dependent binding of the calcium channel antagonist, (+)-[3H]PN200-110, to intact cultured PC12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Cells, Cultured; Isradipine; Kinetics; Membrane Potentials; Nifedipine; Nitrendipine; Onium Compounds; Organophosphorus Compounds; Oxadiazoles; Potassium; Pyridines; Tritium | 1986 |
Pharmacologic and radioligand binding analysis of the actions of 1,4-dihydropyridine activator-antagonist pairs in smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium; Drug Synergism; Guinea Pigs; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Nicotinic Acids; Nitrendipine; Oxadiazoles; Potassium Chloride; Rats; Stereoisomerism | 1986 |
BAY k 8644, a calcium channel agonist, reverses hypotension in endotoxin-shocked rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Male; Microsomes; Myocardium; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Shock, Septic | 1986 |
Dihydropyridine modulation of the chromaffin cell secretory response.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cats; Cell Membrane Permeability; Chromaffin Granules; Chromaffin System; Female; Male; Muscarine; Nicotine; Nitrendipine; Norepinephrine; Perfusion; Potassium; Pyridines | 1987 |
Influence of Mg++ on the effect of diltiazem to increase dihydropyridine binding to receptors on Ca++-channels in chick cardiac and skeletal muscle membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Chickens; Diltiazem; Dose-Response Relationship, Drug; Ion Channels; Isradipine; Magnesium; Membranes; Muscles; Myocardium; Nitrendipine; Oxadiazoles; Receptors, Nicotinic | 1986 |
Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Carcinoma; Cell Line; Diltiazem; Drug Resistance; Glycoproteins; Humans; Nitrendipine; Quinidine; Verapamil; Vinblastine | 1987 |
Effects of a dihydropyridine calcium antagonist and agonist on human basophil histamine release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allergens; Antigens, Plant; Basophils; Calcium; Histamine Release; Humans; In Vitro Techniques; Ion Channels; Leukocytes; Nitrendipine; Plant Proteins; Pollen | 1987 |
Induction of seizures in mice by intracerebroventricular administration of the calcium channel agonist BAY k 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Calcium Channel Blockers; Cerebral Ventricles; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Mice; Mice, Inbred Strains; Nitrendipine; Seizures | 1987 |
Dual effects of dihydropyridines on whole cell and unitary calcium currents in single ventricular cells of guinea-pig.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Ion Channels; Membrane Potentials; Nitrendipine | 1986 |
A comparison between the binding and electrophysiological effects of dihydropyridines on cardiac membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Heart; Ion Channels; Isradipine; Kinetics; Membrane Potentials; Membranes; Myocardium; Nicotinic Acids; Nimodipine; Nitrendipine; Oxadiazoles; Pyridines; Stereoisomerism; Structure-Activity Relationship | 1987 |
Benzodiazepine interactions at neuronal and smooth muscle Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium Radioisotopes; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Neurons; Nitrendipine; Receptors, GABA-A | 1987 |
[3H]BAY K 8644, a 1,4-dihydropyridine Ca++ channel activator: characteristics of binding to high and low affinity sites in cardiac membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Diltiazem; Edetic Acid; Female; Heart Ventricles; Hot Temperature; Kinetics; Lipolysis; Mathematics; Membranes; Myocardium; Nitrendipine; Propylamines; Rabbits; Tiapamil Hydrochloride; Verapamil | 1987 |
45Ca2+ uptake in rat brain neurons: absence of sensitivity to the Ca2+ channel ligands nitrendipine and Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Cadmium; Calcium; Calcium Radioisotopes; Cations, Divalent; Cobalt; Kinetics; Male; Neurons; Nitrendipine; Potassium; Rats | 1987 |
PC12 cells: a model system for studying drug effects on dopamine synthesis and release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brocresine; Cells, Cultured; Cresols; Dihydroxyphenylalanine; Dopamine; Models, Biological; Nitrendipine; Pheochromocytoma; Potassium Chloride; Rats; Reserpine; Sulfonamides | 1987 |
Dihydropyridine-sensitive Ca2+ channels and inositol phospholipid metabolism in ethanol physical dependence.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alcoholism; Animals; Cerebral Cortex; Dihydropyridines; Hydroxydopamines; In Vitro Techniques; Inositol Phosphates; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nitrendipine; Oxidopamine; Pyridines; Rats; Rats, Inbred Strains; Sugar Phosphates; Vas Deferens | 1987 |
Solubilization of calcium channel antagonist binding sites from rat brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain Chemistry; Calcium Channels; Cholic Acids; Kinetics; Male; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Solubility; Verapamil | 1987 |
Dihydropyridine calcium antagonists and agonists in the isolated perfused Dahl rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Glomerular Filtration Rate; Hypertension, Renal; In Vitro Techniques; Ion Channels; Kidney; Male; Nitrendipine; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Renal Circulation; Sodium Chloride; Verapamil | 1987 |
Paradoxical augmentation of (-)Bay K 8644-induced calcium influx by nitrendipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biological Transport; Calcium; Calcium Radioisotopes; Cattle; Coronary Vessels; Drug Synergism; In Vitro Techniques; Isometric Contraction; Kinetics; Muscle, Smooth, Vascular; Nitrendipine | 1987 |
Calcium channels in isolated cells and strips of longitudinal muscle of rat myometrium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Female; In Vitro Techniques; Ion Channels; Muscle, Smooth; Myometrium; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Uterine Contraction | 1987 |
Action of dihydropyridine Ca-channel-modulators on isolated heart preparations.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Coronary Vessels; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Vasodilation | 1987 |
Pharmacologic relevance of dihydropyridine binding sites in membranes from rat aorta: kinetic and equilibrium studies.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Binding, Competitive; Calcium; Calcium Channels; Ion Channels; Isradipine; Kinetics; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Stereoisomerism | 1988 |
Effects of dihydropyridine calcium channel modulators on cardiac sodium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Heart; Ion Channels; Isradipine; Myocardium; Nitrendipine; Oxadiazoles; Rats; Receptors, Nicotinic; Sodium; Stereoisomerism | 1988 |
Altered characteristics of catecholamine release from rat cortical slices and bovine adrenal chromaffin cells in culture after chronic exposure to ethanol and the effect of the dihydropyridine drugs on these systems.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Carbachol; Catecholamines; Cattle; Cerebral Cortex; Chromaffin System; Corpus Striatum; Dihydropyridines; Ethanol; Nitrendipine; Rats | 1987 |
Ca2+ channel ligand activities in uterine smooth muscle: influence of hormonal status.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Estrogens; Female; Ion Channels; Ligands; Muscle, Smooth; Nitrendipine; Potassium; Progesterone; Rats; Uterus | 1987 |
Effects of a phorbol ester on rat aortic contraction and calcium influx in the presence and absence of BAY k 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium; Calcium Channel Agonists; Drug Interactions; In Vitro Techniques; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats | 1987 |
The effects of chemically and electrically-induced convulsions on [3H]nitrendipine binding in mouse brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzodiazepinones; Brain; Calcium Channels; Convulsants; Electroshock; Kinetics; Male; Mice; Mice, Inbred ICR; Nifedipine; Nitrendipine; Pentylenetetrazole; Receptors, Nicotinic; Seizures; Strychnine | 1987 |
Dihydropyridine binding sites regulate calcium influx through specific voltage-sensitive calcium channels in cerebellar granule cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Calcium Radioisotopes; Cations, Divalent; Cell Membrane; Cells, Cultured; Cerebellum; Diltiazem; Electrophysiology; Ion Channels; Neurons; Nifedipine; Nitrendipine; Potassium; Rats; Receptors, Nicotinic; Verapamil | 1988 |
Pharmacological characterization of two calcium currents in GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Dihydropyridines; Electrophysiology; Ion Channels; Nitrendipine; Osmolar Concentration; Pituitary Gland; Rats | 1988 |
Increased vascular response to calcium channel agonist by Dahl S rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Male; Nitrendipine; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Reference Values; Renal Circulation; Sodium, Dietary; Species Specificity; Verapamil | 1988 |
Two types of calcium channels and hormone release in human pituitary tumor cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenoma; Barium; Calcium; Growth Hormone; Hemolytic Plaque Technique; Humans; Ion Channels; Membrane Potentials; Nitrendipine; Pituitary Neoplasms; Prolactin; Tumor Cells, Cultured | 1988 |
Effect of thyroid status on beta-adrenoceptors and calcium channels in rat cardiac and vascular tissue.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Hyperthyroidism; In Vitro Techniques; Iodocyanopindolol; Ion Channels; Isoproterenol; Male; Muscle, Smooth, Vascular; Myocardium; Nitrendipine; Organ Size; Papillary Muscles; Pindolol; Rats; Receptors, Adrenergic, beta; Tail; Thyroid Gland; Thyroxine | 1988 |
Calcium agonist (BayK 8644) augments voltage-sensitive calcium currents but not synaptic transmission in cultured mouse spinal cord neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Cells, Cultured; Electric Stimulation; Ganglia, Spinal; Membrane Potentials; Mice; Nitrendipine; Synaptic Transmission; Tetraethylammonium Compounds; Tetrodotoxin | 1988 |
Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; gamma-Aminobutyric Acid; Ion Channels; Isradipine; Lanthanum; Male; Mice; Neurotransmitter Agents; Nifedipine; Nitrendipine; Oxadiazoles; Potassium; Receptors, Nicotinic; Ruthenium Red; Synaptosomes | 1988 |
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil | 1988 |
Identification and characterization of [3H]nitrendipine binding sites in rat spinal cord.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Kinetics; Male; Nifedipine; Nitrendipine; Quinacrine; Rats; Rats, Inbred Strains; Spinal Cord; Trifluoperazine; Verapamil | 1988 |
Does calcium influx regulate melatonin production through the circadian pacemaker in chick pineal cells? Effects of nitrendipine, Bay K 8644, Co2+, Mn2+, and low external Ca2+.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cations, Divalent; Cells, Cultured; Chickens; Circadian Rhythm; Cobalt; Manganese; Melatonin; Nitrendipine; Pineal Gland; Time Factors | 1988 |
Dihydropyridine-sensitive calcium channel activity related to prolactin, growth hormone, and luteinizing hormone release from anterior pituitary cells in culture: interactions with somatostatin, dopamine, and estrogens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Calcium Radioisotopes; Cells, Cultured; Dihydropyridines; Dopamine; Estradiol; Female; Growth Hormone; Luteinizing Hormone; Male; Nitrendipine; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Potassium; Prolactin; Rats; Rats, Inbred Strains; Sex Characteristics; Somatostatin | 1988 |
Anticonvulsant profile of the dihydropyridine calcium channel antagonists, nitrendipine and nimodipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Aspartic Acid; Atmospheric Pressure; Calcium Channel Blockers; Electrophysiology; Male; N-Methylaspartate; Nimodipine; Nitrendipine; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Strychnine | 1988 |
Inhibition by phenytoin of in vitro secretion of calcitonin from rat thyroid glands and cultured rat C cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcitonin; Calcium; Cells, Cultured; In Vitro Techniques; Nitrendipine; Phenytoin; Rats; Reference Values; Thyroid Gland; Thyroid Neoplasms; Trifluoperazine | 1988 |
Potentiation by neuropeptide Y of vasoconstriction in rat resistance arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium; Calcium Channel Blockers; Dinoprost; Female; In Vitro Techniques; Muscle Contraction; Neuropeptide Y; Nitrendipine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Serotonin; Vasoconstriction | 1988 |
Effect of selective agonists and antagonists on atrial adenosine receptors and their interaction with Bay K 8644 and [3H]-nitrendipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Nitrendipine; Phenylisopropyladenosine; Receptors, Purinergic; Tritium | 1989 |
Relationship between light, calcium influx and cAMP in the acute regulation of melatonin production by cultured chick pineal cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cells, Cultured; Chickens; Circadian Rhythm; Cyclic AMP; Cyclic GMP; Light; Melatonin; Nitrendipine; Norepinephrine; Pineal Gland | 1989 |
Characterization of bradykinin-stimulated release of noradrenaline from cultured bovine adrenal chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bradykinin; Calcium; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol Phosphates; Nicotinic Acids; Nitrendipine; Norepinephrine; Oxadiazoles; Potassium | 1989 |
Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channels; Heart Conduction System; Nitrendipine; Purkinje Fibers; Sheep; Tetrodotoxin | 1989 |
Nitrendipine block of calcium channel currents in vascular smooth muscle and adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Cattle; Cells, Cultured; Electrophysiology; Muscle, Smooth; Nitrendipine; Rats; Zona Glomerulosa | 1988 |
Characterization of the effects of AHN 086, an irreversible ligand of "peripheral" benzodiazepine receptors, on contraction in guinea-pig atrial and ileal longitudinal smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzodiazepinones; Brain; Guinea Pigs; Heart Rate; Ileum; In Vitro Techniques; Male; Membranes; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Nitrendipine; Receptors, GABA-A | 1989 |
Cosecretion of calcitonin and calcitonin gene-related peptide from cultured rat medullary thyroid C cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Neuropeptides; Nitrendipine; Phenytoin; Phorbol Esters; Rats; Thyroid Neoplasms; Trifluoperazine; Tumor Cells, Cultured; Vasodilator Agents | 1989 |
Assessment in pig coronary artery of long-lasting and potent calcium antagonistic actions of the novel dihydropyridine derivative mepirodipine hydrochloride.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Coronary Vessels; Female; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium Chloride; Swine | 1989 |
Voltage-dependent calcium channels in skeletal muscle transverse tubules. Measurements of calcium efflux in membrane vesicles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzothiazoles; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Carbocyanines; Cell Membrane; Dihydropyridines; Edetic Acid; Fluorescent Dyes; Isradipine; Lanthanum; Membrane Potentials; Muscles; Nitrendipine; Oxadiazoles; Potassium; Rabbits; Verapamil | 1989 |
Opposing effects of calcium entry and phorbol esters on fusion of chick muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium Channel Blockers; Cell Fusion; Cells, Cultured; Chick Embryo; Egtazic Acid; Gallopamil; Kinetics; Muscles; Myosin Subfragments; Myosin-Light-Chain Kinase; Myosins; Nitrendipine; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Tetradecanoylphorbol Acetate | 1989 |
Endothelin-1-induced vascular contractions: interactions with drugs affecting the calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Calcium Channel Agonists; Calcium Channel Blockers; Endothelins; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Peptides; Rabbits; Swine | 1989 |
Two calcium channels in basolateral membranes of rabbit ileal epithelial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chlorides; Diltiazem; Egtazic Acid; Electric Conductivity; Epithelium; Ileum; Male; Nifedipine; Nitrendipine; Rabbits; Sodium; Verapamil | 1989 |
Photoaffinity labeling with dihydropyridine derivatives of crude membranes from rat skeletal, cardiac, ileal, and uterine muscles and whole brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Autoradiography; Brain; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Female; Ileum; In Vitro Techniques; Male; Membranes; Muscle, Smooth; Muscles; Myocardium; Nitrendipine; Rats; Spectrometry, Fluorescence; Uterus | 1989 |
Analysis of the effects of (-) and (+) isomers of the 1,4-dihydropyridine calcium channel agonist BAY k 8644 on postrest potentiation in the canine ventricular muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Dogs; Female; Heart Ventricles; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Stereoisomerism | 1989 |
Direct hormonal regulation of smooth muscle calcium current.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Albuterol; Animals; Calcium Channels; Catecholamines; Cattle; Cyclic AMP; GTP-Binding Proteins; Hormones; Isoproterenol; Membrane Potentials; Muscle, Smooth; Nickel; Nitrendipine; Receptors, Adrenergic, beta; Virulence Factors, Bordetella | 1989 |
Barium- and calcium-permeable channels open at negative membrane potentials in rat ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium Channels; Heart Ventricles; In Vitro Techniques; Membrane Potentials; Myocardium; Nitrendipine; Potassium; Rats; Sodium | 1989 |
Genetic up-regulation of calcium channels in a cellular model of ethanol dependence.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Alcoholism; Animals; Calcium Channels; Catecholamines; Cattle; Cells, Cultured; Models, Biological; Nitrendipine; Protein Synthesis Inhibitors; Receptors, Nicotinic; RNA, Messenger; Up-Regulation | 1989 |
Membrane receptors, involved in up-regulation of calcium channels in bovine adrenal chromaffin cells, chronically exposed to ethanol.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Azides; Benzodiazepines; Bicuculline; Calcium Channels; Carbachol; Catecholamines; Cattle; Cells, Cultured; Ethanol; Nitrendipine; Receptors, GABA-A; Receptors, Nicotinic; Time Factors; Up-Regulation | 1989 |
A long lasting Ca2+-activated outward current in guinea-pig atrial myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Apamin; Atrial Function; Caffeine; Calcium; Calcium Channels; Cobalt; Electric Conductivity; Guinea Pigs; Heart; Kinetics; Nitrendipine; Potassium Channels; Quinine; Ryanodine | 1989 |
Electrophysiological and pharmacological evidence that peripheral type benzodiazepine receptors are coupled to calcium channels in the heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Female; Guinea Pigs; Heart; Ion Channels; Isoquinolines; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Receptors, GABA-A; Tetraethylammonium Compounds; Verapamil | 1985 |
Ryanodine as a tool to determine the contributions of calcium entry and calcium release to the calcium transient and contraction of cardiac Purkinje fibers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Aequorin; Alkaloids; Animals; Calcium; Calcium Channel Blockers; Dogs; Female; Heart Conduction System; Ion Channels; Male; Membrane Potentials; Myocardial Contraction; Nifedipine; Nitrendipine; Purkinje Fibers; Ryanodine; Sodium | 1985 |
A dihydropyridine (Bay k 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Electric Stimulation; Female; Guinea Pigs; Ion Channels; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Stimulation, Chemical; Strontium; Time Factors | 1985 |
Dihydropyridine sensitive calcium channels in a smooth muscle cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Cobalt; Dihydropyridines; Ion Channels; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium; Pyridines; Rats | 1985 |
The behavioral effects of the calcium agonist Bay K 8644 in the mouse: antagonism by the calcium antagonist nifedipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Behavior, Animal; Binding, Competitive; Brain; Calcium Channel Blockers; Mice; Motor Activity; Nifedipine; Nitrendipine | 1985 |
Effects of temperature and allosteric modulators on [3H] nitrendipine binding: methods for detecting potential Ca2+ channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Animals; Benzothiazoles; Binding Sites; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Microsomes; Myocardium; Nifedipine; Nitrendipine; Propylamines; Temperature; Thiazoles; Tiapamil Hydrochloride; Verapamil | 1984 |
Interaction of the calcium channel activating 3H-BAY K 8644 and inhibiting 3H-verapamil with specific receptor sites on cultured beating myocardial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Calcium Channel Blockers; Cells, Cultured; Kinetics; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Receptors, Drug; Verapamil | 1984 |
Human red blood cells--an ideal model system for the action of calcium agonists and antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Erythrocytes; Humans; Ion Channels; Nicardipine; Nifedipine; Nitrendipine; Pyridines; Stimulation, Chemical; Verapamil | 1984 |
Novel 1,4-dihydropyridine (Bay K 8644) facilitates calcium-dependent [3H]noradrenaline release from PC 12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Dose-Response Relationship, Drug; Kinetics; Nifedipine; Nitrendipine; Norepinephrine; Pheochromocytoma; Potassium; Rats | 1984 |
Specific binding of a calcium channel activator, [3H]BAY k 8644, to membranes from cardiac muscle and brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Binding, Competitive; Brain; Calcium; Cell Membrane; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Myocardium; Nifedipine; Nitrendipine; Rabbits | 1984 |
Calcium channel 'agonist' BAY K 8644 inhibits calcium antagonist binding to brain and PC12 cell membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Brain; Calcium; Cell Line; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Pheochromocytoma; Rats; Rats, Inbred Strains | 1984 |
Interactions of maitotoxin with voltage-sensitive calcium channels in cultured neuronal cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Diltiazem; Dose-Response Relationship, Drug; Gallopamil; Ion Channels; Marine Toxins; Neurons; Nifedipine; Nitrendipine; Oxocins; Potassium | 1984 |
Calcium channel activation: a different type of drug action.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Calcium Channel Blockers; Cell Line; Diltiazem; Gallopamil; Glioma; Hybrid Cells; Ion Channels; Kinetics; Mice; Neuroblastoma; Nifedipine; Nitrendipine; Pyridines; Rats | 1984 |
Effects of Bay k 8644, a dihydropyridine analog, on [3H]nitrendipine binding to canine cardiac sarcolemma and the relationship to a positive inotropic effect.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Dogs; Myocardial Contraction; Myocardium; Nifedipine; Nitrendipine; Sarcolemma; Stimulation, Chemical | 1984 |
Correlation of nitrendipine and Bay k 8644 binding to isolated canine heart sarcolemma with their pharmacological effects on the canine heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Dogs; Heart; In Vitro Techniques; Kinetics; Myocardium; Nifedipine; Nitrendipine; Sarcolemma | 1984 |
Inhibition of turkey gizzard myosin light chain kinase activity by BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calmodulin; Enzyme Activation; Felodipine; Gizzard, Avian; In Vitro Techniques; Myosin-Light-Chain Kinase; Nifedipine; Nitrendipine; Protein Kinase Inhibitors; Turkeys | 1984 |
BAY K 8644, a 1,4-dihydropyridine Ca2+ channel activator: dissociation of binding and functional effects in brain synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Brain; Calcium; Calcium Channel Blockers; Cerebral Cortex; Guinea Pigs; Ion Channels; Male; Nifedipine; Nitrendipine; Potassium; Rats; Synaptosomes | 1984 |
Characteristics of the binding of [3H]nitrendipine to rabbit ventricular membranes: modification by other Ca++ channel antagonists and by the Ca++ channel agonist Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Cadmium; Calcium Channel Blockers; Female; In Vitro Techniques; Kinetics; Lanthanum; Myocardium; Nifedipine; Nitrendipine; Rabbits; Stereoisomerism; Tritium | 1984 |
Dihydropyridine calcium agonist and antagonist effects on aldosterone secretion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Dantrolene; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium; Stimulation, Chemical | 1984 |
Effects of dihydropyridine calcium channel modulators in the heart: pharmacological and radioligand binding correlations.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rats; Stimulation, Chemical | 1984 |
Effects of nifedipine and Bay K 8644 on myotropic responses in aortic rings of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Kinetics; Muscle Contraction; Nifedipine; Nitrendipine; Phenylephrine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tritium | 1995 |
PCA 50941, a novel Ca2+ channel agonist.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium Channel Agonists; Cardiovascular System; Dihydropyridines; Heart Atria; In Vitro Techniques; Isradipine; Mesenteric Arteries; Muscles; Nitrendipine; Rabbits; Rats; Rats, Sprague-Dawley; Swine; Thiazoles; Vasoconstriction | 1993 |
Parathyroid hormone and hydrochlorothiazide increase calcium transport by the luminal membrane of rabbit distal nephron segments through different pathways.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biological Transport; Calcium; Hydrochlorothiazide; In Vitro Techniques; Kidney Tubules, Distal; Kidney Tubules, Proximal; Membranes; Nephrons; Nitrendipine; Parathyroid Hormone; Peptide Fragments; Rabbits; Teriparatide | 1994 |
Omega 3 polyunsaturated fatty acid modulates dihydropyridine effects on L-type Ca2+ channels, cytosolic Ca2+, and contraction in adult rat cardiac myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arachidonic Acid; Calcium; Calcium Channels; Dihydropyridines; Docosahexaenoic Acids; Fatty Acids, Omega-3; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardial Contraction; Nitrendipine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1994 |
The differential effects of felodipine and nitrendipine on cerebral dihydropyridine binding ex vivo and the ethanol withdrawal syndrome in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bicuculline; Binding Sites; Brain; Ethanol; Felodipine; Isradipine; Male; Mice; Nitrendipine; Substance Withdrawal Syndrome | 1994 |
Role of L-type calcium channels on stimulated calcium influx and on proliferative activity of human coronary smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Blood Physiological Phenomena; Calcium; Calcium Channels; Cell Division; Cells, Cultured; Coronary Vessels; Humans; Muscle, Smooth, Vascular; Nitrendipine | 1994 |
Identification of dihydropyridine (DHP) binding sites on cultured monkey renal cells (GMRC) with a photoaffinity probe (-)-[3H]-azidopine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Azides; Binding Sites; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chlorocebus aethiops; Dihydropyridines; Kidney; Kinetics; Muscle Proteins; Nisoldipine; Nitrendipine; Propanolamines; Receptors, Adrenergic, beta | 1994 |
Competitive binding experiments reveal differential interactions for dihydropyridine calcium channel activators and antagonists at dihydropyridine receptors on mouse brain membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Brain; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; In Vitro Techniques; Male; Membranes; Mice; Muscle Proteins; Nicotinic Acids; Nitrendipine; Oxadiazoles; Stereoisomerism; Thermodynamics | 1994 |
Effects of diltiazem in convulsive states differ from those previously reported for dihydropyridine calcium channel antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Convulsants; Diltiazem; Infusions, Intravenous; Male; Mice; Mice, Inbred Strains; Nitrendipine; Seizures | 1994 |
Effect of the calcium channel agonist Bay K8644 on mechanical and electrical responses of frog skeletal muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; Nitrendipine; Rana pipiens | 1994 |
The dihydropyridine nitrendipine inhibits [3H]MK 801 binding to mouse brain sections.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Autoradiography; Binding, Competitive; Brain; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Nifedipine; Nimodipine; Nitrendipine; Software; Verapamil | 1994 |
Functional properties of cardiac L-type calcium channels transiently expressed in HEK293 cells. Roles of alpha 1 and beta subunits.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Barium; Calcium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Electrophysiology; Humans; Isradipine; Kinetics; Muscle Proteins; Myocardium; Nitrendipine; Time Factors; Transfection | 1995 |
Boar sperm plasma membrane Ca(2+)-selective channels in planar lipid bilayers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cell Membrane; Dihydropyridines; Electrophysiology; Lipid Bilayers; Male; Nitrendipine; Spermatozoa; Stereoisomerism; Swine | 1995 |
Effects of Ca2+ channel antagonist subtypes on mitochondrial Ca2+ transport.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Cattle; Diltiazem; Flunarizine; In Vitro Techniques; Mitochondria; Nitrendipine; Verapamil | 1995 |
Influence of Ca2+ channel modulators on [3H]purine release from rat cultured glial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Corpus Striatum; Egtazic Acid; Electric Stimulation; Fetus; Fluorescent Dyes; Fura-2; Kinetics; Neuroglia; Nitrendipine; omega-Conotoxins; Peptides; Purines; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Time Factors; Tritium | 1995 |
Specific bindings of [3H](+)PN200-110 and [125I]omega-conotoxin to crude membranes from differentiated NG108-15 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Bucladesine; Cell Differentiation; Cell Membrane; Diltiazem; Glioma; Hybrid Cells; Isradipine; Mollusk Venoms; Neuroblastoma; Nitrendipine; omega-Conotoxin GVIA; Potassium Chloride; Rats; Tumor Cells, Cultured; Verapamil | 1993 |
Effect of short-term ethanol treatment on voltage-dependent calcium channels in Kupffer cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cells, Cultured; Electrophysiology; Ethanol; Extracellular Space; Female; Intracellular Membranes; Kupffer Cells; Nitrendipine; Osmolar Concentration; Potassium; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Age, endothelium and aortic reactivity to calcium in Wistar rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Animals; Aorta, Thoracic; Calcium; Endothelium, Vascular; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Rats; Rats, Wistar | 1993 |
Involvement of calcium and L-type channels in nicotine-induced antinociception.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesia; Animals; Behavior, Animal; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels; Injections, Spinal; Intracellular Fluid; Kinetics; Male; Mecamylamine; Mice; Mice, Inbred ICR; Nicotine; Nitrendipine; Nociceptors; Pain Measurement; Rats; Receptors, Nicotinic; Terpenes; Thapsigargin; Tritium | 1993 |
Calcium fluxes, ion currents and dihydropyridine receptors in a new immortal cell line from rat heart muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Cell Differentiation; Cell Division; Cell Line; Heart; Immunohistochemistry; Male; Membrane Potentials; Muscle Proteins; Myocardium; Nitrendipine; Pyridines; Rats; Rats, Inbred F344; Time Factors; Tritium | 1993 |
Dihydropyridine antagonists and agonists of calcium channels inhibit the induction of nitric oxide synthase by endotoxin in cultured macrophages.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Oxidoreductases; Animals; Calcium Channel Blockers; Cell Line; Endotoxins; Enzyme Induction; Escherichia coli; Kinetics; Lipopolysaccharides; Macrophages; Mice; Nimodipine; Nisoldipine; Nitrendipine; Nitric Oxide Synthase | 1993 |
Ionic mechanisms involved in the secretory effects of histamine in the rat adrenal medulla.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium; Catecholamines; Female; Histamine; In Vitro Techniques; Nitrendipine; Rats; Rats, Sprague-Dawley; Sodium | 1993 |
Dihydropyridine-sensitive and -insensitive voltage-operated calcium channels participate in the control of glucose-induced insulin release from human pancreatic beta cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Mollusk Venoms; Nitrendipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides | 1996 |
Regulation of melatonin synthesis in rainbow trout (Oncorhyncus mykiss) pineal organs: effects of calcium depletion and calcium channel drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cyclic AMP; Dose-Response Relationship, Drug; Melatonin; Nitrendipine; omega-Conotoxin GVIA; Oncorhynchus mykiss; Organ Culture Techniques; Peptides; Pineal Gland; Time Factors | 1997 |
Altered behavioral sensitivity of Ca(2+)-modulating drugs after chronic nicotine administration in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics; Animals; Behavior, Animal; Binding Sites; Brain; Calcium; Calcium Channels; Drug Tolerance; Ion Transport; Male; Mice; Mice, Inbred ICR; Motor Activity; Nicotine; Nitrendipine; Thapsigargin; Tritium | 1997 |
Effects of N- and L-type calcium channel antagonists and (+/-)-Bay K8644 on nerve-induced catecholamine secretion from bovine perfused adrenal glands.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Glands; Animals; Calcium Channel Blockers; Calcium Channels; Catecholamines; Cattle; Choline; Electric Stimulation; Neostigmine; Nitrendipine; omega-Conotoxin GVIA; Peptides; Perfusion; Splanchnic Nerves | 1997 |
Ovariectomy and estrogen-induced alterations in myocardial contractility in female rabbits: role of the L-type calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channels; Diethylstilbestrol; Estradiol; Female; Isoproterenol; Myocardial Contraction; Nitrendipine; Ovariectomy; Papillary Muscles; Rabbits; Time Factors | 1998 |
Acetylcholine triggers L-glutamate exocytosis via nicotinic receptors and inhibits melatonin synthesis in rat pinealocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Arylamine N-Acetyltransferase; Atropine; Bungarotoxins; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cells, Cultured; Diltiazem; Exocytosis; Glutamic Acid; Melatonin; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nifedipine; Nitrendipine; Oxotremorine; Parasympathetic Nervous System; Pineal Gland; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine; Synaptic Vesicles; Tubocurarine | 1998 |
L-type Ca2+ channels in inspiratory neurones of mice and their modulation by hypoxia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aerobiosis; Ammonium Chloride; Animals; Animals, Newborn; Barium; Calcium Channels; Calcium Channels, L-Type; Cell Hypoxia; In Vitro Techniques; Inhalation; Ion Channel Gating; Medulla Oblongata; Membrane Potentials; Mice; Neurons; Nifedipine; Nitrendipine; Patch-Clamp Techniques; Probability; Quaternary Ammonium Compounds | 1998 |
A calcium agonist, Bay k 8644, suppresses the embryotoxic effects induced by dihydropyridines calcium channel blockers in cultured rat embryos.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Culture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Male; Nicardipine; Nifedipine; Nitrendipine; Rats; Rats, Sprague-Dawley | 1998 |
Endothelin 1 action on isolated rat stomach and the role of calcium ions in ET 1 induced depolarization of smooth muscle cells BC3H1.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic Antagonists; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Line; Cholinergic Antagonists; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Membrane Potentials; Mice; Muscle Contraction; Muscle, Smooth; Nitrendipine; omega-Conotoxin GVIA; Peptides; Serotonin Antagonists; Stomach; Thapsigargin | 1998 |
L-type calcium channels contribute to the tottering mouse dystonic episodes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Calcium Channels, L-Type; Diltiazem; Dystonia; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mutation; Nitrendipine; RNA, Messenger; Seizures | 1999 |
Intracellular Ca2+ concentrations in cultured chicken photoreceptor cells: sustained elevation in depolarized cells and the role of dihydropyridine-sensitive Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chick Embryo; Membrane Potentials; Nifedipine; Nitrendipine; Photoreceptor Cells, Vertebrate; Time Factors | 1999 |
Different contributions of voltage-sensitive Ca2+ channels to histamine-induced catecholamine release and tyrosine hydroxylase activation in bovine adrenal chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Calcium Channel Blockers; Calcium Channels; Catecholamines; Cattle; Chromaffin Cells; Dose-Response Relationship, Drug; GTP-Binding Proteins; Histamine; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Spider Venoms; Tetrodotoxin; Tyrosine 3-Monooxygenase | 1999 |
Damaging effects of the calcium paradox are reduced in isolated hearts from ethanol-dependent rats: paradoxic effects of dihydropyridine drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alcoholism; Animals; Calcium; Calcium Channel Blockers; Central Nervous System Depressants; Dihydropyridines; Ethanol; Heart; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardium; Nitrendipine; Perfusion; Rats; Rats, Sprague-Dawley | 1999 |
Calcium channel activation and self-biting in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior | 1999 |
Two types of pharmacologically distinct Ca(2+) currents with voltage-dependent similarities in zona fasciculata cells isolated from bovine adrenal gland.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cattle; Cells, Cultured; Membrane Potentials; Nickel; Nitrendipine; Patch-Clamp Techniques; Zona Fasciculata | 2000 |
Functional alteration of dihydropyridine-sensitive Ca(2+) channels in the adrenal glomerulosa of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Radioisotopes; Cell Membrane; Female; Nifedipine; Nitrendipine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tritium; Verapamil; Zona Glomerulosa | 2000 |
Dihydropyridine-induced Ca2+ release from ryanodine-sensitive Ca2+ pools in human skeletal muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Humans; Muscle, Skeletal; Nifedipine; Nitrendipine; PC12 Cells; Protein Conformation; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel | 2000 |
Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Chloride Channels; Dihydropyridines; Drug Interactions; Glycine; Neural Inhibition; Neurons; Nicardipine; Nifedipine; Nitrendipine; Rats; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Synaptic Transmission; Verapamil | 2001 |
On the nature and origin of the calcium asymmetry arising during gravitropic response in etiolated pea epicotyls.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Biological Transport; Calcimycin; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cycloheximide; Glycosides; Gravitation; Gravitropism; Hydrogen-Ion Concentration; Indoleacetic Acids; Ionophores; Nisoldipine; Nitrendipine; Pisum sativum; Plant Growth Regulators; Plant Shoots; Protein Synthesis Inhibitors; Protoplasts | 1987 |
Mechanism of angiotensin II-induced phospholipase D activation in bovine adrenal glomerulosa cells.
Topics: 1-Butanol; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aldosterone; Angiotensin II; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Carbazoles; Cattle; Cells, Cultured; Diglycerides; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Indoles; Ionomycin; Nitrendipine; Phospholipase D; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Zona Glomerulosa | 2002 |
Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Colforsin; Cyclic AMP; Dihydropyridines; Electrophysiology; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Ion Channels; Isoproterenol; Manganese; Membrane Potentials; Myocardium; Myocytes, Cardiac; Nitrendipine; Patch-Clamp Techniques; Rabbits; Signal Transduction | 2003 |
Isoflurane inhibits cyclic adenosine monophosphate response element-binding protein phosphorylation and calmodulin translocation to the nucleus of SH-SY5Y cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Active Transport, Cell Nucleus; Anesthetics, Inhalation; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calmodulin; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Down-Regulation; Humans; Isoflurane; Membrane Potentials; Neuroblastoma; Neurons; Nitrendipine; omega-Conotoxin GVIA; Phosphorylation; Potassium Chloride; Time Factors | 2009 |
Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Dihydropyridines; Enzyme Inhibitors; Guinea Pigs; Humans; Isradipine; Molecular Structure; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship | 1996 |