nitrates has been researched along with ursodeoxycholic acid in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 10 (71.43) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Invernizzi, P; O'Connor, M; Salzman, AL; Setchell, KD; Szabó, C; Ueta, I | 1 |
| Del Soldato, P; Fiorucci, S; Ignarro, LJ; Mencarelli, A; Morelli, A; Palazzetti, B | 1 |
| Antonelli, E; Casini, A; del Soldato, P; Fiorucci, S; Mello, T; Mencarelli, A; Morelli, A; Morelli, O; Palazzetti, B; Tallet, D | 1 |
| Antonelli, E; Fiorucci, S; Morelli, A | 1 |
| Acuto, G; Antonelli, E; Baldoni, M; Brancaleone, V; Clerici, C; Del Soldato, P; Distrutti, E; Fiorucci, S; Morelli, A; Orlandi, S; Sanpaolo, L | 1 |
| Cadelina, GW; Groszmann, RJ; Iwakiri, Y; Loureiro-Silva, MR | 1 |
| Antonelli, E; Fiorucci, S; Morelli, A; Tocchetti, P | 1 |
| Wallace, JL | 1 |
| Antonelli, E; Del Soldato, P; Distrutti, E; Farneti, S; Fiorucci, S; Mencarelli, A; Morelli, A | 1 |
| Peng, SX; Tian, JD; Zhang, YH | 1 |
| Chabli, A; Colin, P; Elimadi, A; Haddad, PS; Ouazzani-Chahdi, A; Spénard, J | 1 |
| Bellot, P; Berzigotti, A; Bosch, J; De Gottardi, A; Gagnon, C; Garcia-Pagan, JC; Spénard, J | 1 |
| Chen, L; Shang, J; Tian, JD; Wang, ZF; Zhang, YH | 1 |
| Majee, C; Mishra, R; Sahu, R | 1 |
3 review(s) available for nitrates and ursodeoxycholic acid
| Article | Year |
|---|---|
Treatment of portal hypertension with NCX-1000, a liver-specific NO donor. A review of its current status.
Topics: Animals; Clinical Trials as Topic; Humans; Hypertension, Portal; Liver; Nitrates; Nitric Oxide; Nitric Oxide Donors; Ursodeoxycholic Acid | 2004 |
[Targeting of nitric oxide-donor and related drugs].
Topics: Animals; Apoptosis; Azo Compounds; Cell Line, Tumor; Drug Delivery Systems; Humans; Liver; Liver Neoplasms; Nitrates; Nitric Oxide Donors; Oleanolic Acid; Piperazines; Ursodeoxycholic Acid | 2006 |
An insight into primary biliary cholangitis and its recent advances in treatment: semi-synthetic analogs to combat ursodeoxycholic-acid resistance.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholic Acids; Humans; Liver Cirrhosis, Biliary; Nitrates; Ursodeoxycholic Acid | 2020 |
1 trial(s) available for nitrates and ursodeoxycholic acid
| Article | Year |
|---|---|
NCX-1000, a nitric oxide-releasing derivative of UDCA, does not decrease portal pressure in patients with cirrhosis: results of a randomized, double-blind, dose-escalating study.
Topics: Administration, Oral; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Male; Manometry; Maximum Tolerated Dose; Middle Aged; Nitrates; Nitric Oxide Donors; Portal Pressure; Reference Values; Risk Assessment; Severity of Illness Index; Treatment Failure; Ursodeoxycholic Acid | 2010 |
10 other study(ies) available for nitrates and ursodeoxycholic acid
| Article | Year |
|---|---|
Ursodeoxycholate inhibits induction of NOS in human intestinal epithelial cells and in vivo.
Topics: Adenocarcinoma; Animals; Cell Line, Transformed; Cell Survival; Enzyme Induction; Enzyme Repression; Humans; Intestinal Mucosa; Intestinal Neoplasms; Kinetics; Lipopolysaccharides; Mitochondria; Molsidomine; Nitrates; Nitric Oxide Synthase; Nitrites; Oxygen Consumption; Rats; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Ursodeoxycholic Acid | 1997 |
An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity.
Topics: Animals; Base Sequence; Caspase Inhibitors; Cysteine Proteinase Inhibitors; Cytokines; DNA Primers; Down-Regulation; Fas Ligand Protein; Hepatitis, Autoimmune; Humans; Liver; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Nitrates; RNA, Messenger; Salicylates; Tumor Cells, Cultured; Ursodeoxycholic Acid | 2001 |
NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension.
Topics: Animals; Carbon Tetrachloride; Collagen; Hypertension, Portal; Liver; Liver Cirrhosis; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; Salicylates; Ursodeoxycholic Acid | 2001 |
Nitric oxide and portal hypertension: a nitric oxide-releasing derivative of ursodeoxycholic acid that selectively releases nitric oxide in the liver.
Topics: Adipocytes; Animals; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Nitrates; Nitric Oxide; Ursodeoxycholic Acid | 2003 |
NCX-1000, a nitric oxide-releasing derivative of ursodeoxycholic acid, ameliorates portal hypertension and lowers norepinephrine-induced intrahepatic resistance in the isolated and perfused rat liver.
Topics: Animals; Bile; Blood Pressure; Drug Interactions; Hypertension, Portal; In Vitro Techniques; Liver Circulation; Liver Cirrhosis; Male; Nitrates; Nitric Oxide Donors; Norepinephrine; Perfusion; Rats; Rats, Wistar; Ursodeoxycholic Acid; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2003 |
A liver-specific nitric oxide donor improves the intra-hepatic vascular response to both portal blood flow increase and methoxamine in cirrhotic rats.
Topics: Animals; Drug Interactions; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Male; Mesenteric Artery, Superior; Methoxamine; Nitrates; Nitric Oxide Donors; Portal Vein; Rats; Rats, Sprague-Dawley; Ursodeoxycholic Acid; Vascular Resistance; Vasoconstrictor Agents | 2003 |
Acetaminophen hepatotoxicity: NO to the rescue.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Liver; Mice; Nitrates; Nitric Oxide; Nitric Oxide Donors; Ursodeoxycholic Acid | 2004 |
Liver delivery of NO by NCX-1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Caspases; Cell Separation; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Cytosol; Hepatocytes; Liver; Liver Failure; Membrane Potentials; Mice; Mitochondria, Liver; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Sulfhydryl Compounds; Ursodeoxycholic Acid | 2004 |
Combining ursodeoxycholic acid or its NO-releasing derivative NCX-1000 with lipophilic antioxidants better protects mouse hepatocytes against amiodarone toxicity.
Topics: Amiodarone; Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Cells, Cultured; Dose-Response Relationship, Drug; Fatty Liver; Hepatocytes; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Nitrates; Protective Agents; Superoxides; Ursodeoxycholic Acid | 2007 |
[Synthesis and biological evaluation of nitrate-oleanolic acid hybrids as inhibitors of HepG2 cell apoptosis].
Topics: Antioxidants; Apoptosis; Hep G2 Cells; Humans; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oleanolic Acid; Structure-Activity Relationship; Ursodeoxycholic Acid | 2010 |