nitrates has been researched along with sinitrodil in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 20 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bache, RJ; Duncker, DJ; Mizrahi, J | 1 |
| Benedini, F; Bertolini, G; Cereda, R; Donà, G; Gromo, G; Levi, S; Mizrahi, J; Sala, A | 1 |
| Benedini, F; Bertolini, G; Gromo, G; Mizrahi, J; Sala, A | 1 |
| Berdeaux, A; Dubois-Randé, JL; Ghaleh, B; Giudicelli, JF; Hittinger, L | 1 |
| Bergamaschi, M; Gromo, G; Mizrahi, J; Nonaka, K; Ueno, A | 1 |
| Bassenge, E; Cereda, R; Fink, B | 2 |
| Barsotti, G; Cereda, R; Chiaverini, F; Gromo, G; L'Abbate, A; Magnozzi, D; Mizrahi, J; Pelosi, G; Taddei, L; Trivella, MG | 1 |
| Agozzino, S; Bergamaschi, M; Bravi, F; Cereda, R; Gromo, G; Mascheroni, G; Mizrahi, J | 1 |
| Agozzino, S; Bernareggi, M; Berti, F; Cereda, R; Giuliani, P; Mizrahi, J; Rossoni, G; Villa, L | 1 |
| Boulanger, CM; Desta, B; Nakashima, M; Vanhoutte, PM | 1 |
| Cremonesi, P; Donà, G; Giuliani, P; Mizrahi, J; Passaro, A; Stella, P; Tursi, F | 1 |
| Coltro, G; Jiritano, L; Monzani, MV; Sala, A | 2 |
| Bianchini, C; Love, R; Mizrahi, J; Monzani, V; Sardina, M | 1 |
| Bianchini, C; Boyce, M; Johnston, A; Sardina, M; Warrington, SJ | 1 |
| Boyce, M; Khattar, RS; Lahiri, A; Sardina, M; Senior, R | 1 |
| Coltro, G; Monzani, MV; Sala, A; Sardina, M | 1 |
| Casiraghi, A; Minghetti, P; Montanari, L; Monzani, MV | 1 |
| Balkestein, EJ; Sardina, M; Spek, JJ; Struijker Boudier, HA; Van Bortel, LM | 1 |
1 review(s) available for nitrates and sinitrodil
| Article | Year |
|---|---|
The discovery of a new organic nitrate: an overview.
Topics: Animals; Benzoxazines; Humans; Nitrates; Oxazines; Vasodilator Agents | 1995 |
5 trial(s) available for nitrates and sinitrodil
| Article | Year |
|---|---|
Safety and pharmacologic activity of a new nitrate ester, ITF 296, after intravenous administration in healthy volunteers.
Topics: Adolescent; Adult; Benzoxazines; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Nitrates; Oxazines; Vasodilator Agents | 1995 |
Hemodynamic and humoral effects at rest and after head-up tilt tests during 24-hour infusion of a new nitrate ester, ITF 296, compared with ISDN and placebo in healthy volunteers: a double-blind, randomized, within-subject study.
Topics: Adult; Benzoxazines; Blood Pressure; Cross-Over Studies; Double-Blind Method; Electrocardiography; Epinephrine; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Neurotransmitter Agents; Nitrates; Norepinephrine; Oxazines; Posture; Renin; Vasodilator Agents | 1995 |
Safety, tolerability, and antiischaemic efficacy of ITF-296, a nitric oxide donor, in patients with chronic stable angina.
Topics: Aged; Angina Pectoris; Benzoxazines; Double-Blind Method; Exercise Test; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Ischemia; Nitrates; Oxazines | 1998 |
Pharmacokinetics of ITF 296 (Sinitrodil) a novel organic nitrate, in healthy volunteers.
Topics: Adolescent; Adult; Benzoxazines; Cross-Over Studies; Double-Blind Method; Humans; Infusions, Intravenous; Male; Nitrates; Oxazines | 1999 |
Is it possible to develop drugs that act more selectively on large arteries?
Topics: Adult; Arteries; Benzoxazines; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Design; Humans; Isosorbide Dinitrate; Male; Nitrates; Nitric Oxide Donors; Oxazines; Pulse; Vascular Resistance; Vasodilation; Vasodilator Agents | 1999 |
14 other study(ies) available for nitrates and sinitrodil
| Article | Year |
|---|---|
Nitrovasodilators ITF 296 and isosorbide dinitrate exert antiischemic activity by dilating coronary penetrating arteries.
Topics: Analysis of Variance; Animals; Benzoxazines; Blood Pressure; Coronary Circulation; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dogs; Exercise Test; Heart Rate; Injections, Intravenous; Isosorbide Dinitrate; Laser-Doppler Flowmetry; Myocardial Ischemia; Myocardium; Nitrates; Oxazines; Vasodilation | 1995 |
New antianginal nitro esters with reduced hypotensive activity. Synthesis and pharmacological evaluation of 3-[(nitrooxy)alkyl]-2H-1,3-benzoxazin-4(3H)-ones.
Topics: Angina Pectoris; Animals; Benzoxazines; Blood Pressure; Hemodynamics; Hypotension; In Vitro Techniques; Ischemia; Male; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Oxazines; Rabbits; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Vasodilator Agents | 1995 |
ITF 296, a new endothelium-independent vasodilator: comparison with nitroglycerin and isosorbide dinitrate.
Topics: Animals; Benzoxazines; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemodynamics; Isosorbide Dinitrate; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Oxazines; Vasodilator Agents | 1995 |
Effect of the new nitrate ester ITF 296 on coronary and systemic hemodynamics in the conscious dog: comparison with nitroglycerin and nicorandil.
Topics: Animals; Benzoxazines; Coronary Circulation; Coronary Vessels; Dogs; Female; Hemodynamics; Injections, Intravenous; Male; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Oxazines; Vasodilator Agents | 1995 |
Effect of ITF 296 on total effective vascular compliance in the anesthetized dog under autonomic blockade.
Topics: Anesthesia; Animals; Autonomic Nerve Block; Benzoxazines; Blood Pressure; Dogs; Female; Hemodynamics; Male; Molsidomine; Muscle Tonus; Nitrates; Nitroglycerin; Oxazines; Vascular Resistance; Vasodilator Agents | 1995 |
Effects of ITF 296 on epicardial coronary artery diameter during acute and long-term treatment in the conscious dog.
Topics: Animals; Benzoxazines; Blood Pressure; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Infusions, Intravenous; Male; Nitrates; Oxazines; Time Factors; Vasodilator Agents | 1995 |
The new nitroderivative ITF 296 improves collateral blood flow in a canine model of coronary thrombosis.
Topics: Anesthesia; Animals; Benzoxazines; Collateral Circulation; Coronary Circulation; Coronary Thrombosis; Dogs; Female; Isosorbide Dinitrate; Male; Microspheres; Nitrates; Oxazines; Vasodilator Agents | 1995 |
Protective effect of the nitrate ester ITF 296 against methacholine-induced myocardial ischemia in the anesthetized rat.
Topics: Administration, Oral; Anesthesia; Animals; Benzoxazines; Hemodynamics; Infusions, Intravenous; Male; Methacholine Chloride; Myocardial Ischemia; Nitrates; Oxazines; Parasympathomimetics; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1995 |
Protective effects of ITF 296 in the isolated rabbit heart subjected to global ischemia.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzoxazines; Enzyme Inhibitors; Epoprostenol; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide Synthase; omega-N-Methylarginine; Oxazines; Rabbits; Vasodilator Agents | 1995 |
The nitrate ester ITF 296 relaxes isolated canine arteries and veins.
Topics: Animals; Arteries; Benzoxazines; Dogs; Electrophysiology; Endothelium, Vascular; Female; In Vitro Techniques; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Oxazines; Vasodilator Agents; Veins | 1995 |
Mechanism of ITF 296-induced vasorelaxation compared to nitroglycerin and isosorbide dinitrate: relationship between relaxation of rabbit aorta and tissue cGMP.
Topics: Animals; Aorta, Thoracic; Benzoxazines; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Oxazines; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Pharmacokinetic profile of ITF 296 in rats and dogs.
Topics: Administration, Oral; Animals; Benzoxazines; Biological Availability; Biotransformation; Dogs; Female; Injections, Intravenous; Male; Nitrates; Oxazines; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1995 |
Simultaneous determination of ITF 296 and two metabolites in plasma by a validated HPLC method.
Topics: Animals; Benzoxazines; Calibration; Chromatography, High Pressure Liquid; Dogs; Nitrates; Oxazines; Spectrophotometry, Ultraviolet; Tablets | 1997 |
In vitro skin permeation of Sinitrodil, a member of a new class of nitrovasodilator drugs.
Topics: Benzoxazines; Humans; In Vitro Techniques; Nitrates; Oxazines; Skin Absorption; Vasodilator Agents | 1999 |