nitrates has been researched along with simvastatin in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 12 (57.14) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuroiwa, A; Nakashima, Y; Tanaka, S; Tasaki, H; Toyokawa, Y; Yamashita, K; Yashiro, A | 1 |
| Angius, MF; Brizzi, P; Carboni, A; Cherchi, GM; Ciccarese, M; Formato, M; Maioli, M; Melis, MG; Tonolo, G | 1 |
| Hayashi, T; Iguchi, A; Kano, H; Sumi, D; Thakur, NK; Tsunekawa, T | 1 |
| Abdalla, DS; Bersch, D; Bertolami, MC; Faludi, AA; Pereira, EC; Salem, M | 1 |
| Antunes-Rodrigues, J; Carnio, EC; da Rocha, MJ; Elias, LL; Felix, JV; Giusti-Paiva, A; Martinez, MR | 1 |
| Ahn, JY; Ahn, TH; Choi, IS; Han, SH; Jeong, EM; Jin, DK; Kim, HS; Koh, KK; Shin, EK | 1 |
| Selley, ML | 1 |
| Hein, TW; Izumi, N; Kuo, L; Nagaoka, T; Sato, E; Takahashi, A; Yoshida, A | 1 |
| Chan, CY; Chang, FY; Chen, YC; Chu, CJ; Huang, HC; Lee, FY; Lee, SD; Lin, HC; Wang, SS | 1 |
| Acín, S; Arbonés-Mainar, JM; Carnicer, R; Guillén, N; Navarro, MA; Osada, J; Surra, JC | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Takenouchi, Y | 1 |
| Alvarez de Sotomayor, M; Herrera, MD; Marhuenda, E; Mingorance, C; Vega, S | 1 |
| Larsen, W; Mandleco, B | 1 |
| Andreadou, I; Farmakis, D; Fotopoulou, T; Iliodromitis, EK; Ioannidis, K; Kremastinos, DT; Paraskevaidis, IA; Prokovas, E; Zoga, A | 1 |
| Chang, CC; Chen, YC; Huang, HC; Lee, FY; Lee, JY; Lee, SD; Lin, HC; Wang, SS | 1 |
| Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA | 1 |
| Kaminsky, Y; Kosenko, E; Suslikov, A; Tikhonova, L | 1 |
| Helmy, MM | 1 |
| Brito, GA; Dalcico, R; de Menezes, AM; Deocleciano, OB; Oriá, RB; Ribeiro, RA; Vale, ML | 1 |
| Alberici, LC; Catalão, CHR; da Costa, LHA; Rocha, MJA; Santos-Júnior, NN; Souza, AO | 1 |
| Ekladious, ST; El Sayed, NS | 1 |
5 trial(s) available for nitrates and simvastatin
| Article | Year |
|---|---|
Additive effects of Simvastatin beyond its effects on LDL cholesterol in hypertensive type 2 diabetic patients.
Topics: Albuminuria; Anticholesteremic Agents; Apolipoproteins; Blood Pressure; Cholesterol, LDL; Cholestyramine Resin; Diabetes Mellitus, Type 2; Female; Glycosaminoglycans; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitrites; Simvastatin | 2000 |
Effects of simvastatin and L-arginine on vasodilation, nitric oxide metabolites and endogenous NOS inhibitors in hypercholesterolemic subjects.
Topics: Anticholesteremic Agents; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Free Radicals; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; S-Nitrosothiols; Simvastatin; Time Factors; Vasodilation | 2003 |
Comparative effects of statin and fibrate on nitric oxide bioactivity and matrix metalloproteinase in hyperlipidemia.
Topics: Brachial Artery; Coronary Artery Disease; Female; Fenofibrate; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Matrix Metalloproteinases; Middle Aged; Nitrates; Nitric Oxide; Simvastatin; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha; Vasodilation | 2004 |
Effect of systemic administration of simvastatin on retinal circulation.
Topics: Administration, Oral; Adult; Blood Flow Velocity; Blood Pressure; Cholesterol; Cross-Over Studies; Double-Blind Method; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Nitrates; Nitrites; Regional Blood Flow; Retinal Vessels; Simvastatin | 2006 |
Impacts of lisinopril and lisinopril plus simvastatin on erythrocyte and plasma arginase, nitrite, and nitrate in hypertensive patients.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arginase; Atherosclerosis; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Lisinopril; Male; Middle Aged; Nitrates; Nitrites; Simvastatin | 2012 |
16 other study(ies) available for nitrates and simvastatin
| Article | Year |
|---|---|
Simvastatin increases plasma NO2- and NO3- levels in patients with hypercholesterolemia.
Topics: Administration, Oral; Anticholesteremic Agents; Cholesterol, LDL; Cholesterol, VLDL; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Nitrates; Nitrites; Simvastatin; Ultracentrifugation | 1996 |
HMG-CoA reductase inhibitor stabilizes rabbit atheroma by increasing basal NO and decreasing superoxide.
Topics: Animals; Aorta; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Rabbits; RNA, Messenger; Simvastatin; Superoxides; Vasoconstriction | 2001 |
Simvastatin decreases nitric oxide overproduction and reverts the impaired vascular responsiveness induced by endotoxic shock in rats.
Topics: Animals; Blood Pressure; Cholesterol; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Pressure; Protein Isoforms; Rats; Rats, Wistar; Shock, Septic; Simvastatin; Time Factors | 2004 |
Simvastatin prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion and protein tyrosine nitration in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Cholesterol; Dopamine; Dopamine Agents; Homovanillic Acid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Microglia; Neostriatum; Nitrates; Nitric Oxide; Oxidants; Simvastatin; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine | 2005 |
Simvastatin for rats with thioacetamide-induced liver failure and encephalopathy.
Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Disease Models, Animal; Enzyme Inhibitors; Hepatic Encephalopathy; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Failure, Acute; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Simvastatin; Thioacetamide; Time Factors | 2008 |
Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine beta-synthase and apolipoprotein A-I.
Topics: Animals; Antihypertensive Agents; Aorta; Apolipoprotein A-I; Blood Pressure; Blotting, Western; Chromatography, Liquid; Cystathionine beta-Synthase; Endothelium, Vascular; Heterozygote; Hypertension; Lipoproteins; Male; Mice; Nitrates; Nitric Oxide; Nitrites; Simvastatin | 2008 |
Possible involvement of Akt activity in endothelial dysfunction in type 2 diabetic mice.
Topics: Adrenomedullin; Animals; Aorta; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Clonidine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Male; Mice; Mice, Inbred ICR; Nitrates; Nitrites; Nitroprusside; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Simvastatin; Vasodilation; Vasodilator Agents | 2008 |
Effects of HMG-CoA reductase inhibition by simvastatin on vascular dysfunction induced by lipopolysaccharide in rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Sepsis; Simvastatin | 2008 |
Chest pain with angiographic clear coronary arteries: A provider's approach to cardiac syndrome X.
Topics: Adrenergic Uptake Inhibitors; Anticholesteremic Agents; Coronary Angiography; Coronary Circulation; Coronary Vessels; Diltiazem; Dyspnea; Female; Humans; Imipramine; Microcirculation; Microvascular Angina; Middle Aged; Nitrates; Risk Factors; Simvastatin; Vasodilator Agents | 2009 |
Simvastatin in contrast to postconditioning reduces infarct size in hyperlipidemic rabbits: possible role of oxidative/nitrosative stress attenuation.
Topics: Animals; Anticholesteremic Agents; Biomarkers; Cholesterol, LDL; Hemodynamics; Hypercholesterolemia; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitrites; Oxidative Stress; Rabbits; Simvastatin; Tyrosine | 2010 |
Simvastatin effects on portal-systemic collaterals of portal hypertensive rats.
Topics: Animals; Arginine Vasopressin; Collateral Circulation; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Male; Membrane Proteins; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Portal Pressure; Portal System; Rats; Rats, Sprague-Dawley; RNA, Messenger; Simvastatin; Thromboxane B2; Thromboxane-A Synthase; Time Factors; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
Topics: Aerosols; Animals; Arginase; Arginine; Asthma; Blotting, Western; Coloring Agents; Disease Models, Animal; Goblet Cells; Hydroxyproline; Hyperplasia; Immunohistochemistry; Inflammation; Lung; Mice; Nitrates; Nitrites; Ovalbumin; Simvastatin; Transforming Growth Factor beta1 | 2010 |
Potential hepato-protective effect of α-tocopherol or simvastatin in aged rats.
Topics: Age Factors; Aging; alpha-Tocopherol; Animals; Antioxidants; Catalase; Lipids; Liver; Liver Diseases; Male; Nitrates; Nitrites; Rats; Rats, Wistar; Simvastatin; Thiobarbituric Acid Reactive Substances | 2012 |
Protective mechanisms of simvastatin in experimental periodontal disease.
Topics: Alanine Transaminase; Alkaline Phosphatase; Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Bone Morphogenetic Protein 2; Female; Gingiva; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-10; Interleukin-1beta; Malondialdehyde; Matrix Metalloproteinase 1; Matrix Metalloproteinase 8; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Osteoprotegerin; Oxidative Stress; Periodontitis; Peroxidase; RANK Ligand; Rats; Rats, Wistar; Receptor Activator of Nuclear Factor-kappa B; Simvastatin; Tumor Necrosis Factor-alpha | 2013 |
Brain Oxidative Stress During Experimental Sepsis Is Attenuated by Simvastatin Administration.
Topics: Animals; Apoptosis; Brain; Caspase 3; Cecum; Citrate (si)-Synthase; Cytokines; Glial Fibrillary Acidic Protein; Hippocampus; Ligation; Male; Models, Biological; Nitrates; Oxidative Stress; Prefrontal Cortex; Punctures; Rats, Wistar; Sepsis; Simvastatin; Thiobarbituric Acid Reactive Substances | 2017 |
Effect of pioglitazone and simvastatin in lipopolysaccharide-induced amyloidogenesis and cognitive impairment in mice: possible role of glutamatergic pathway and oxidative stress.
Topics: Amyloid beta-Peptides; Animals; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glutamic Acid; Lipopolysaccharides; Male; Maze Learning; Mice; Neuroprotective Agents; Nitrates; Oxidative Stress; Peptide Fragments; Pioglitazone; Recognition, Psychology; Signal Transduction; Simvastatin | 2019 |