nitrates and sildenafil citrate

nitrates has been researched along with sildenafil citrate in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	12 (28.57)	18.2507
2000's	22 (52.38)	29.6817
2010's	8 (19.05)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Conti, CR	1
Billner, KL	1
Maisch, B	1
Lycklama à Nijeholt, AA	1
Licht, MR	1
Leliefeld, HH	1
Ishikura, F	1
Manecke, RG; Mulhall, JP	1
O'Rourke, M; Xiong-Jing, J	1
Crowley, T; Gingell, C; Levy, A	1
Biron, CR	1
Khoury, V; Kritharides, L	1
Kloner, RA	1
Osinski, MT; Rauch, BH; Schrör, K	1
Feely, J; Williams, D	1
James, JS	1
Bassenge, E; Fink, B; Hartmann, B; Hess, U; Schwemmer, M; Stoeter, M	1
Howes, L	1
Chu, PL; Gibson, S; Henne, J; McFarland, W; Miller, P; Partridge, T; Schwarcz, S; Weide, D	1
Iglesias, ML; Jericó, C; Pedro-Botet, J; Skaf, E	1
Sussman, DO	1
Bendhack, LM; Castro, MM; Nagassaki, S; Rascado, RR; Rizzi, E; Tanus-Santos, JE	1
Cerquetani, E; Fini, M; Marazzi, G; Mercuro, G; Patrizi, R; Rosano, GM; Vitale, C; Volterrani, M	1
Simon, HB	1
Dias-Junior, CA; Evora, PR; Moreno, H; Souza-Silva, AR; Tanus-Santos, JE; Uzuelli, JA	1
Dias-Junior, CA; Tanus-Santos, JE	1
Scheindlin, S	1
Guhring, P; Mulhall, JP; Müller, A; Parker, M; Shelton, J	1
Patterson, TL; Semple, SJ; Strathdee, SA; Zians, J	1
Egawa, T; Ikeda, M; Kameyama, N; Kataoka, Y; Sejima, H; Shibuya, K; Shuto, H; Tominaga, K; Yamauchi, A	1
Cauli, O; Felipo, V; Garcia-Verdugo, JM; Gómez-Pinedo, U; Herraiz, S; Pellicer, A; Pellicer, B; Rodrigo, R	1
Allmen, Hv; Chang, LL; Harper, K; Henderson, SC; Hornbuckle, K; Ma, M	1
Dias-Junior, CA; Montenegro, MF; Neto-Neves, EM; Tanus-Santos, JE	1
Lehmann, J; Roegler, C	1
Cakmak, HA; Ikitimur, B; Karadag, B; Ongen, Z	1
Abdel-latif, RG; El-Moselhy, MA; Khalifa, MA; Morsy, MA	1
Afrazi, A; Billiar, TR; Binion, DG; Branca, MF; Egan, CE; Gladwin, MT; Good, M; Hackam, DJ; Jia, H; Lee, EK; Lin, J; Ma, C; Neal, MD; Ozolek, J; Prindle, T; Richardson, WM; Sodhi, CP; Yazji, I	1
Adamkov, M; Balentova, S; Calkovska, A; Kolomaznik, M; Kosutova, P; Mikolka, P; Mokra, D; Mokry, J	1

Reviews

7 review(s) available for nitrates and sildenafil citrate

Article	Year
Erectile dysfunction and sildenafil. The Nurse practitioner, 1998, Volume: 23, Issue:11 Topics: Drug Interactions; Enzyme Inhibitors; Erectile Dysfunction; Female; Humans; Nitrates; Piperazines; Purines; Sildenafil Citrate; Sulfones	1998
Use of oral sildenafil (Viagra) in the treatment of erectile dysfunction. Comprehensive therapy, 1999, Volume: 25, Issue:2 Topics: Clinical Trials as Topic; Contraindications; Drug Synergism; Erectile Dysfunction; Humans; Hypotension; Male; Nitrates; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	1999
Medical treatment of erectile dysfunction. Annals of medicine, 1999, Volume: 31, Issue:6 Topics: Adrenergic alpha-Antagonists; Aged; Alprostadil; Clinical Trials as Topic; Dopamine Agonists; Drug Interactions; Erectile Dysfunction; Hemodynamics; Humans; Male; Nitrates; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents	1999
Non-surgical management of erectile dysfunction. Clinical endocrinology, 2000, Volume: 52, Issue:3 Topics: Administration, Topical; Alprostadil; Erectile Dysfunction; Humans; Male; Middle Aged; Nitrates; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Psychotherapy; Purines; Sildenafil Citrate; Sulfones; Testosterone; Vacuum; Vasodilator Agents	2000
Sex and the patient with cardiovascular risk factors: focus on sildenafil. The American journal of medicine, 2000, Dec-18, Volume: 109 Suppl 9A Topics: Antihypertensive Agents; Contraindications; Drug Synergism; Erectile Dysfunction; Humans; Male; Myocardial Ischemia; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Risk Factors; Sex Factors; Sildenafil Citrate; Sulfones; Vasodilation; Vasodilator Agents	2000
Pharmacokinetics, pharmacodynamics, and efficacy of phosphodiesterase type 5 inhibitors. The Journal of the American Osteopathic Association, 2004, Volume: 104, Issue:3 Suppl 4 Topics: Antihypertensive Agents; Cardiovascular Diseases; Diabetes Complications; Drug Interactions; Erectile Dysfunction; Humans; Imidazoles; Male; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Treatment Outcome; Triazines; Vardenafil Dihydrochloride	2004
[Medicinal chemistry of nitrates and PDE5 inhibitors]. Pharmazie in unserer Zeit, 2010, Volume: 39, Issue:5 Topics: Endothelium-Dependent Relaxing Factors; Erectile Dysfunction; Humans; Male; Models, Molecular; Nitrates; Nitric Oxide; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Sildenafil Citrate; Structure-Activity Relationship; Sulfones; Vasodilator Agents	2010

Trials

1 trial(s) available for nitrates and sildenafil citrate

Article	Year
Comparison of trimetazidine plus sildenafil to chronic nitrates in the control of myocardial ischemia during sexual activity in patients with coronary artery disease. The American journal of cardiology, 2005, Feb-01, Volume: 95, Issue:3 Topics: Adult; Aged; Analysis of Variance; Coitus; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Electrocardiography, Ambulatory; Erectile Dysfunction; Humans; Male; Middle Aged; Myocardial Ischemia; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Treatment Outcome; Trimetazidine; Vasodilator Agents	2005

Article

Year

Comparison of trimetazidine plus sildenafil to chronic nitrates in the control of myocardial ischemia during sexual activity in patients with coronary artery disease.

The American journal of cardiology, 2005, Feb-01, Volume: 95, Issue:3

Topics: Adult; Aged; Analysis of Variance; Coitus; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Electrocardiography, Ambulatory; Erectile Dysfunction; Humans; Male; Middle Aged; Myocardial Ischemia; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Treatment Outcome; Trimetazidine; Vasodilator Agents

2005

Other Studies

34 other study(ies) available for nitrates and sildenafil citrate

Article	Year
Viagra, the latest cardio-VASCULAR drug. Clinical cardiology, 1998, Volume: 21, Issue:9 Topics: Cardiovascular System; Contraindications; Drug Interactions; Enzyme Inhibitors; Erectile Dysfunction; Humans; Liver; Male; Nitrates; Piperazines; Purines; Sildenafil Citrate; Sulfones	1998
Viagra: beyond the jokes. Harvard heart letter : from Harvard Medical School, 1998, Volume: 9, Issue:2 Topics: Cyclic GMP; Drug Interactions; Erectile Dysfunction; Humans; Hypotension; Male; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Risk Factors; Sildenafil Citrate; Sulfones	1998
[Therapy recommendations for adverse effects of Viagra and nitrates (NO-donors)]. Herz, 1998, Volume: 23, Issue:7 Topics: Angina Pectoris; Blood Pressure; Contraindications; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; Molsidomine; Nicorandil; Nitrates; Nitric Oxide Donors; Piperazines; Purines; Sildenafil Citrate; Sulfones	1998
[The erection pill]. Nederlands tijdschrift voor geneeskunde, 1998, Oct-24, Volume: 142, Issue:43 Topics: Adult; Age Factors; Aged; Cardiovascular Diseases; Contraindications; Drug Interactions; Erectile Dysfunction; Humans; Male; Middle Aged; Nitrates; Piperazines; Purines; Sildenafil Citrate; Sulfones	1998
[Treatment of chronic anal fissures with nitrate ointment]. Nederlands tijdschrift voor geneeskunde, 1999, Feb-13, Volume: 143, Issue:7 Topics: Adult; Aged; Contraindications; Drug Interactions; Female; Fissure in Ano; Humans; Middle Aged; Nitrates; Ointments; Piperazines; Pregnancy; Purines; Sildenafil Citrate; Sulfones	1999
A statement on the use of sildenafil in the management of sexual dysfunction in patients with cardiovascular disease. Heart and Stroke Foundation of Canada. Canadian Cardiovascular Society. The Canadian journal of cardiology, 1999, Volume: 15, Issue:4 Topics: Cardiovascular Diseases; Contraindications; Decision Trees; Erectile Dysfunction; Humans; Male; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	1999
[Viagra landing: the dawn of sexual science in cardiology]. Journal of cardiology, 1999, Volume: 34, Issue:3 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Coronary Disease; Drug Synergism; Erectile Dysfunction; Humans; Male; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	1999
Managing sexual dysfunction. Using sildenafil for patients with cardiovascular disease. Heart and Stroke Foundation of Canada. Canadian Cardiovascular Society. Canadian family physician Medecin de famille canadien, 2000, Volume: 46 Topics: Cardiovascular Diseases; Contraindications; Erectile Dysfunction; Humans; Hypotension; Male; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Risk Factors; Sildenafil Citrate; Sulfones	2000
Sildenafil/nitrate interaction. Circulation, 2000, Feb-29, Volume: 101, Issue:8 Topics: Contraindications; Drug Interactions; Humans; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	2000
Viagra presents special concerns for the hygienist and the dental team. RDH, 1998, Volume: 18, Issue:10 Topics: Chest Pain; Contraindications; Dental Care; Drug Interactions; Erectile Dysfunction; Humans; Hypotension; Male; Medical History Taking; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	1998
Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension. Australian and New Zealand journal of medicine, 2000, Volume: 30, Issue:5 Topics: Aged; Angina Pectoris; Coronary Angiography; Diltiazem; Humans; Hypotension; Male; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	2000
Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A. Molecular pharmacology, 2001, Volume: 59, Issue:5 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antineoplastic Agents; Cattle; Cell Adhesion Molecules; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Dextrans; DNA; Drug Synergism; Enzyme Activation; Microfilament Proteins; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Donors; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Purines; Sildenafil Citrate; Sulfones	2001
Initial uptake in use of sildenafil in general practice. European journal of clinical pharmacology, 2001, Volume: 56, Issue:12 Topics: Adolescent; Adult; Aged; Drug Interactions; Erectile Dysfunction; Family Practice; Humans; Ireland; Male; Middle Aged; Nitrates; Pharmacoepidemiology; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	2001
Viagra: new warning with protease inhibitors. AIDS treatment news, 1999, May-07, Issue:No 318 Topics: Drug Interactions; Erectile Dysfunction; HIV Infections; HIV Protease Inhibitors; Humans; Male; Nitrates; Piperazines; Purines; Sildenafil Citrate; Sulfones	1999
Potentiation of sildenafil-induced hypotension is minimal with nitrates generating a radical intermediate. Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:1 Topics: Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Female; Free Radicals; Heart Rate; Hypotension; Male; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	2001
Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension. Internal medicine journal, 2001, Volume: 31, Issue:6 Topics: Aged; Cardiac Catheterization; Cardiovascular Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Diltiazem; Drug Interactions; Erectile Dysfunction; Humans; Hypotension; Male; Mixed Function Oxygenases; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	2001
[Erectile dysfunction. Help also for cardiac patients]. MMW Fortschritte der Medizin, 2001, Oct-11, Volume: 143, Issue:41 Topics: Apomorphine; Contraindications; Coronary Disease; Drug Interactions; Erectile Dysfunction; Humans; Male; Molsidomine; Nitrates; Piperazines; Purines; Sildenafil Citrate; Sulfones	2001
Viagra use in a community-recruited sample of men who have sex with men, San Francisco. Journal of acquired immune deficiency syndromes (1999), 2003, Jun-01, Volume: 33, Issue:2 Topics: Adult; Condoms; HIV Infections; Homosexuality, Male; Humans; Logistic Models; Male; Middle Aged; Nitrates; Pentanols; Piperazines; Population Surveillance; Prevalence; Purines; Risk Factors; Safe Sex; San Francisco; Sexual Behavior; Sildenafil Citrate; Sulfones; Surveys and Questionnaires	2003
Sildenafil and coronary artery disease. BJU international, 2003, Volume: 92, Issue:7 Topics: Contraindications; Erectile Dysfunction; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Risk Factors; Self Administration; Sildenafil Citrate; Sulfones	2003
Atorvastatin enhances sildenafil-induced vasodilation through nitric oxide-mediated mechanisms. European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3 Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Aorta, Thoracic; Atorvastatin; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heptanoic Acids; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Acid; Nitric Oxide Synthase; Nitrites; Piperazines; Purines; Pyrroles; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Vasodilation; Vasodilator Agents	2004
On call. I am 66 years old and have had angina for nearly 5 years. I take aspirin and Zocor, but I haven't needed nitroglycerin for at least 3 years, even though I ride my bike quite hard at least 4 days a week. I've started having trouble with my erectio Harvard men's health watch, 2005, Volume: 10, Issue:1 Topics: Aged; Blood Pressure; Coitus; Contraindications; Humans; Imidazoles; Male; Nitrates; Piperazines; Purines; Sildenafil Citrate; Sulfones; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents	2005
Hemodynamic effects of combined sildenafil and L-arginine during acute pulmonary embolism-induced pulmonary hypertension. European journal of pharmacology, 2005, Nov-07, Volume: 524, Issue:1-3 Topics: Acute Disease; Analysis of Variance; Animals; Arginine; Blood Pressure; Cyclic GMP; Dogs; Female; Heart Rate; Hypertension, Pulmonary; Infusions, Intravenous; Male; Nitrates; Nitrites; Piperazines; Pulmonary Artery; Pulmonary Embolism; Purines; Respiration; Sildenafil Citrate; Sulfones; Time Factors; Vasodilator Agents	2005
Hemodynamic effects of sildenafil interaction with a nitric oxide donor compound in a dog model of acute pulmonary embolism. Life sciences, 2006, Jun-27, Volume: 79, Issue:5 Topics: Animals; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dogs; Drug Interactions; Female; Heart Rate; Hemodynamics; Male; Nitrates; Nitric Oxide Donors; Nitrites; Piperazines; Pulmonary Artery; Pulmonary Embolism; Purines; Respiration; Sildenafil Citrate; Sulfones; Time Factors; Vascular Resistance	2006
When she says yes, but he needs no: some reflections on nitric oxide. Molecular interventions, 2006, Volume: 6, Issue:1 Topics: Female; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Piperazines; Purines; Racial Groups; Sildenafil Citrate; Sulfones; Vasodilator Agents	2006
Nitrate cessation profiles in men wishing to use sildenafil citrate. Urology, 2007, Volume: 69, Issue:5 Topics: Adult; Age Factors; Aged; Cohort Studies; Confidence Intervals; Drug Interactions; Erectile Dysfunction; Follow-Up Studies; Humans; Male; Middle Aged; Nitrates; Piperazines; Probability; Purines; Risk Assessment; Sildenafil Citrate; Sulfones; Treatment Outcome; Vasodilator Agents; Withholding Treatment	2007
Sexual marathons and methamphetamine use among HIV-positive men who have sex with men. Archives of sexual behavior, 2009, Volume: 38, Issue:4 Topics: Adult; Alcohol-Related Disorders; Central Nervous System Stimulants; HIV Infections; Homosexuality, Male; Humans; Logistic Models; Male; Methamphetamine; Multivariate Analysis; Neuropsychological Tests; Nitrates; Pentanols; Piperazines; Purines; Risk-Taking; Sexual Behavior; Sildenafil Citrate; Substance-Related Disorders; Sulfones; Vasodilator Agents	2009
Gender differences in tail-skin flushing induced by nitrates and phosphodiesterase type 5 inhibitors in a climacteric mouse model. European journal of pharmacology, 2009, Dec-10, Volume: 624, Issue:1-3 Topics: Animals; Carbolines; Climacteric; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Flushing; Gene Expression Regulation; Imidazoles; Male; Mice; Mice, Inbred ICR; Models, Animal; Nitrates; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purines; RNA, Messenger; Sex Characteristics; Sildenafil Citrate; Skin; Sulfones; Tadalafil; Tail; Triazines; Vardenafil Dihydrochloride	2009
cGMP modulates stem cells differentiation to neurons in brain in vivo. Neuroscience, 2010, Feb-17, Volume: 165, Issue:4 Topics: Animals; Apoptosis; Brain; Cell Differentiation; Cerebral Cortex; Cyclic GMP; Enzyme Inhibitors; Hippocampus; Neurogenesis; Neurons; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Phosphodiesterase Inhibitors; Piperazines; Prefrontal Cortex; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Stem Cells; Sulfones	2010
Co-possession of phosphodiesterase type-5 inhibitors (PDE5-I) with nitrates. Current medical research and opinion, 2010, Volume: 26, Issue:6 Topics: Adolescent; Adult; Aged; Carbolines; Databases, Factual; Drug Therapy, Combination; Erectile Dysfunction; Humans; Imidazoles; Male; Middle Aged; Nitrates; Pharmaceutical Services; Phosphodiesterase Inhibitors; Piperazines; Practice Patterns, Physicians'; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Young Adult	2010
Hemodynamic effects of inducible nitric oxide synthase inhibition combined with sildenafil during acute pulmonary embolism. Nitric oxide : biology and chemistry, 2010, Dec-15, Volume: 23, Issue:4 Topics: Acute Disease; Animals; Dogs; Female; Hemodynamics; Isothiuronium; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Piperazines; Pulmonary Embolism; Purines; Sildenafil Citrate; Sulfones; Thiobarbituric Acid Reactive Substances	2010
An unusual adverse effect of sildenafil citrate: acute myocardial infarction in a nitrate-free patient. BMJ case reports, 2012, Oct-19, Volume: 2012 Topics: Adult; Blood Pressure; Coitus; Coronary Occlusion; Coronary Vessels; Humans; Male; Myocardial Infarction; Nitrates; Piperazines; Purines; Risk Factors; Sildenafil Citrate; Stents; Sulfones; Vasodilator Agents	2012
Sildenafil protects against nitric oxide deficiency-related nephrotoxicity in cyclosporine A treated rats. European journal of pharmacology, 2013, Apr-05, Volume: 705, Issue:1-3 Topics: Albuminuria; Animals; Catalase; Creatinine; Cyclosporine; Glutathione; Immunosuppressive Agents; Kidney Diseases; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Phosphodiesterase 5 Inhibitors; Piperazines; Protective Agents; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Urea	2013
Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling. Proceedings of the National Academy of Sciences of the United States of America, 2013, Jun-04, Volume: 110, Issue:23 Topics: Analysis of Variance; Animals; Animals, Newborn; Enterocolitis, Necrotizing; Infant Formula; Intestinal Mucosa; Mice; Mice, Knockout; Microcirculation; Microscopy, Confocal; Milk, Human; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones; Toll-Like Receptor 4	2013
Effects of phosphodiesterase 5 inhibitor sildenafil on the respiratory parameters, inflammation and apoptosis in a saline lavage-induced model of acute lung injury. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2018, Volume: 69, Issue:5 Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Bronchoalveolar Lavage; Cytokines; Disease Models, Animal; Epithelial Cells; Neutrophils; Nitrates; Nitrites; Phosphodiesterase 5 Inhibitors; Pulmonary Ventilation; Rabbits; Saline Solution; Sildenafil Citrate	2018