nitrates has been researched along with nitroglycerin in 547 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 281 (51.37) | 18.7374 |
| 1990's | 121 (22.12) | 18.2507 |
| 2000's | 98 (17.92) | 29.6817 |
| 2010's | 34 (6.22) | 24.3611 |
| 2020's | 13 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Niederberger, M | 1 |
| Klaus, W | 1 |
| Asmterdam, EA; Mason, DT | 1 |
| Murao, S; Uchida, Y; Yoshimoto, N | 2 |
| Brix, W; Hochrein, H; Lehmann, HU | 1 |
| Angell, WW; Bilisoly, J; Hultgren, HN; Lipton, MJ; Pfeifer, JF | 1 |
| Chumburidze, VB; Kaverina, NV | 1 |
| Schrey, A | 1 |
| Francis, GS; Warren, SE | 1 |
| Baitsch, G; Bertel, O; Burkart, F; Elsässer, S; Ritz, R | 1 |
| Conti, G; Del Guercio, R; Esposito, C; Leone, C | 1 |
| Mathey, D | 1 |
| Aronow, WS | 4 |
| Brundage, BH; Chatterjee, K; Ports, TA | 1 |
| Mah, PK | 1 |
| Halawa, B | 1 |
| Araki, H; Horio, Y; Sakanashi, M; Takenaka, F | 1 |
| Imai, S; Katano, Y; Kitagawa, T; Nakagawa, Y; Otorii, T; Takeda, K; Tsukada, T | 1 |
| Morton, WE | 1 |
| Kotler, MN; Likoff, W; Segal, BL | 1 |
| Ogawa, T; Rose, HB; Takano, TT; Vyden, JK | 1 |
| Goldstein, RE | 1 |
| Alimurung, B; Fletcher, GF; Watt, E | 1 |
| Cohn, JN; Franciosa, JA | 1 |
| Preston, TA; Richtsmeier, TE | 1 |
| Amsterdam, EA; Awan, N; Mason, DT; Miller, RR | 1 |
| Abrams, J | 13 |
| Jasiński, K; Poprawski, K | 1 |
| Davidson, IW; Di Carlo, FJ; Parker, JC | 1 |
| Bender, HW; Faulkner, SL; Fisher, RD; Friesinger, GC | 1 |
| Gough, AW | 1 |
| Krantz, JC; Leake, CD | 1 |
| Behrenbeck, DW; Hilger, HH; Niehues, B; Tauchert, M | 1 |
| di Carlo, FJ | 1 |
| Needleman, P | 2 |
| Chrostowski, JE; Holmes, RN; Rehn, BW | 1 |
| Reichek, N | 3 |
| Dacian, S; Dirschinger, J; Fleck, E; Loracher, C; Rudolph, W | 1 |
| Long, JP; Ma, S | 1 |
| Kutishenko, NP; Martsevich, SIu; Metelitsa, VI | 1 |
| Groszmann, RJ; Rodríguez-Pérez, F | 1 |
| Schmid, M; Yeates, RA | 1 |
| Feelisch, M; Noack, E; Schönafinger, K | 1 |
| Bennett, BM; Long, PG; McDonald, BJ; Nigam, R; Simon, WC | 1 |
| Evdokimova, AG; Iunusov, MA; Kirichenko, LL; Masenko, VP | 1 |
| Benet, LZ; Gumbleton, M; Han, C; Lau, DT | 1 |
| Bussmann, WD | 1 |
| Hammerschlag, BC; Perucho-Powell, MH; Rand, JH; Reich, DL; Thys, DM | 1 |
| Pepine, CJ | 1 |
| Horowitz, JD | 2 |
| Werkö, L | 1 |
| Kuhn, M | 1 |
| Cantor, E; Greenberg, SS; Ho, E; Walega, M | 1 |
| Fung, HL; Kowaluk, EA | 1 |
| Feelisch, M; Noack, E | 1 |
| Henry, PJ; Horowitz, JD; Louis, WJ | 2 |
| Förster, S; Schröder, H; Schrör, K; Woditsch, I | 1 |
| Almange, C; Clement, C; Foulgoc, JL; Laurent, M; Le Helloco, A; Leborgne, O; Leborgne, P | 1 |
| van der Giessen, WJ; van Woerkens, LJ; Verdouw, PD | 1 |
| Boulanger, CM; Lüscher, TF | 1 |
| Leitold, M; Yeates, RA; Zimmermann, T | 1 |
| Ioseliani, DG; Rishko, NV | 1 |
| Lahti, T; Wahl, M; Wiklund, I; Wilson, A | 1 |
| Kober, G; Schulz, W | 1 |
| Shub, C | 1 |
| Holzmann, S; Kukovetz, WR | 4 |
| Baldenkov, GN; Mazaev, AV; Mukharliamov, NM; Negrescu, EV; Sazonova, LN; Tkachuk, VA | 1 |
| Jonsson, UE | 1 |
| Parker, JO | 3 |
| Silber, S | 2 |
| Dirschinger, J; Hall, D; Rudolph, W | 1 |
| Scheidt, S | 1 |
| Bochkareva, EV; Kokurina, EV; Metelitsa, VI; Vodop'ianova, RS | 1 |
| Katz, RJ | 1 |
| Berezov, VM; Boch, VK; Roshchin, SI; Roshchina, GN; Varlamov, AM; Verzilov, SN | 1 |
| Bennett, BM; McDonald, BJ | 1 |
| Bogaert, M | 1 |
| Noack, E | 1 |
| Bayeric, A; Dirschinger, J; Hall, D; Reiniger, G; Rudolph, W | 1 |
| Pollavini, G; Scardi, S | 1 |
| Ignarro, LJ | 2 |
| Kots, IaI; Solonovich, TG | 1 |
| Kokurina, EV; Martsevich, SIu; Metelitsa, VI; Slastnikova, ID; Urumbaev, RK | 1 |
| Cherevatov, BG; Kucherenko, OD; Matlakhov, AN; Shapkin, EI; Shelest, AN | 1 |
| Lichtlen, PR | 2 |
| Engelmann, L; Frömmel, H; Kucher, A; Wetzler, G | 1 |
| Krol, AA; Lazebnik, LB; Shutemova, EA | 1 |
| Penkov, N; Sirakova, V | 1 |
| Lekkerkerker, JF | 1 |
| Weber, S | 1 |
| Ahlner, J; Axelsson, KL; Torfgård, K | 1 |
| Metelitsa, VI | 1 |
| Hashimoto, H; Ito, T; Nakagawa, H; Ogawa, K; Okumura, K; Satake, T | 1 |
| Müller, R; Noack, E; Schröder, H | 1 |
| Ioseliani, DG; Movelidze, TA; Mshvidobadze, TA; Vasilidze, TV | 1 |
| Broustet, JP; Douard, H; Mora, B | 1 |
| Holzmann, S; Kukovetz, WR; Romanin, C | 1 |
| Yusuf, S | 1 |
| Bennett, A; Melhuish, PB; Stamford, IF | 1 |
| Collins, R; MacMahon, S; Peto, R; Yusuf, S | 1 |
| Bennett, BM; Hayward, LD; Murad, F; Schröder, H; Waldman, SA | 1 |
| Kukovetz, WR; Romanin, C | 1 |
| Bassenge, E; Busse, R; Mülsch, A | 1 |
| Kadyraliev, KK; Mirrakhimov, MM; Moldotashev, IK | 1 |
| Metcalf, WK; Tarburton, JP | 1 |
| Lemmer, B | 1 |
| Taylor, SH | 1 |
| Flaherty, JT | 1 |
| Cowan, JC | 1 |
| Deans, KW; Hartshorn, JC | 1 |
| Ahlner, J; Axelsson, KL; Ljusegren, ME | 1 |
| Carlens, P | 1 |
| Bassenge, E; Stewart, DJ | 1 |
| Jähnchen, E | 1 |
| Fung, HL; Poliszczuk, R | 1 |
| Bonzel, T; Chen, C; Hasenfuss, G; Holubarsch, C; Just, H; Krehl, F; von Herrath, M | 1 |
| Kaltenbach, M; Schneider, W | 1 |
| Kopalova, SM; Lesniak, EA; Pomerantsev, VP | 1 |
| Larin, NV; Pakulin, IA; Semin, SN; Sil'vestrov, VP; Surovov, IuA | 1 |
| Barkve, TF; Gjesdal, K | 1 |
| Berlin, R | 1 |
| Kampmann, JP | 1 |
| Nyberg, G | 1 |
| Jaeger, H; Lutz, D; Michaelis, K; Salama, ZB | 1 |
| Chinoy, DA | 1 |
| Zeller, FP | 1 |
| Klamerus, KJ; Zeller, FP | 1 |
| Chong, S; Fung, HL; Hough, K; Kakemi, M; Kowaluk, E | 1 |
| Ahland, B; König, E; Schrör, K; Weiss, P | 1 |
| Szycher, M | 1 |
| Sharpe, N | 1 |
| De Caterina, R; Dorso, CR; Tack-Goldman, K; Weksler, BB | 1 |
| Corwin, S; Reiffel, JA | 1 |
| Beck, OA | 1 |
| Luomanmäki, K | 1 |
| Bridgman, KM; Carr, M; Tattersall, AB | 1 |
| Imhof, PR | 1 |
| Shell, WE | 1 |
| Frishman, WH | 1 |
| Offerhaus, L | 1 |
| Kokurina, EV; Martsevich, SIu; Metelitsa, VI; Piotrovskiĭ, VK | 1 |
| Fung, HL | 3 |
| Gorlin, R; Lesch, M | 1 |
| Bartel, AG; Behar, VS; Kong, Y; McNeer, JF; Peter, RH; Rosati, RA; Starmer, CF | 1 |
| Fortuin, NJ | 1 |
| Bogaert, MG; Rosseel, MT | 2 |
| Fink, GB; Stipe, AA | 1 |
| Keyriläinen, O; Nyberg, G; Uusitalo, AJ | 1 |
| Clark, DG; Litchfield, MH | 2 |
| Hastings, SG | 1 |
| Epstein, SE; Goldstein, RE | 1 |
| Tempero, KF | 1 |
| Messini, M | 1 |
| Cermáková, B; Kuzelová, M | 1 |
| Midkiff, CR; Washington, WD | 1 |
| Kempe, CR; Tannert, WK | 1 |
| Komura, S | 1 |
| Gautieri, RF; Ward, CO | 1 |
| Barnes, RW | 1 |
| Jacob, JC; Maroun, FB | 1 |
| Blum, SW; Hefner, MA; Howe, BB; Quinn, JB; Winbury, MM | 1 |
| Hunter, FE; Needleman, P | 1 |
| Gautieri, RF; Mancini, RT | 1 |
| Siepe, O | 1 |
| DiCarlo, FJ; Melgar, MD | 1 |
| Belpaire, FM; Lee, NH | 2 |
| Phipps, FC; Stokinger, HE | 1 |
| Krantz, JC | 1 |
| Wendt, RL | 1 |
| Cohn, KE; Selzer, A; Strauss, G; Sweatman, T | 1 |
| Johnson, EM; Lang, S; Needleman, P | 1 |
| Blehm, DJ; Harkey, AB; Johnson, EM; Needleman, P | 1 |
| Bogaert, MG | 2 |
| Kaye, H; Mills, B; Winsor, T | 1 |
| Jones, RC; Trainor, DC | 1 |
| Lorenzetti, OJ; Nelson, JW; Tye, A | 2 |
| Murray, WJ; Williams, AF | 1 |
| Bieliński, E; Bubień, Z; Debowy, J; Garbuliński, T | 1 |
| Morikawa, Y | 1 |
| Rogers, WJ; Turner, RA | 1 |
| Wendkos, MH | 2 |
| Horton, GE; Johnson, PC | 1 |
| Gudbjarnason, S; Ogawa, K | 1 |
| Cavagna, G; Foa, V; Locati, G; Vigliani, EC | 1 |
| Crew, MC; DiCarlo, FJ; Gala, RL; Haynes, LJ; Melgar, MD | 1 |
| Blehm, DJ; Needleman, P; Rotskoff, KS | 1 |
| Aronow, WS; Kaplan, MA | 1 |
| Spesshardt, K | 1 |
| Aviado, DM; Bellet, S; Folle, LE | 1 |
| Kalin, M; Kylin, B; Malmfors, T | 1 |
| Hefner, MA; Howe, BB; Winbury, MM | 1 |
| Moravec, DF | 1 |
| Bogaert, MG; De Schaepdryver, AF; Rosseel, MT | 2 |
| Frick, MH; Heikkilä, J | 1 |
| Levy, JV | 1 |
| Aronow, WS; Chesluk, HM | 2 |
| Bermudez, GA; Butterfield, TK; Goldbarg, AN; Moran, JF; Nemickas, R | 1 |
| Bermudez, GA; Butterfield, TK; Goldbarg, AN; Morgan, JF; Nemickas, R | 1 |
| Semler, HJ | 1 |
| Evans, JM; Gorman, PA | 1 |
| Beiser, GD; Epstein, SE; Goldstein, RE; Redwood, DR; Rosing, DR | 1 |
| Davies, A | 1 |
| Nager, F | 1 |
| Ipsen, J | 1 |
| Belpaire, FM; Bogaert, MG; Rosseel, MT | 1 |
| Bogaert, MG; Herman, AG | 1 |
| Leslie, RE | 1 |
| Da Costa, BC; Gensini, GG; Huntington, PP; Kelly, AE | 1 |
| Litchfield, MH | 1 |
| Boime, I; Hunter, FE | 1 |
| Kalin, M; Kylin, B | 1 |
| Osnes, JB | 1 |
| Tancredi, RG | 1 |
| Opie, LH | 1 |
| Bache, RJ | 1 |
| Bragina, GI | 1 |
| Reeves, TJ | 1 |
| Weser, C | 1 |
| Goldschlager, N; Goosby, E | 1 |
| Bassenge, E; Busse, R | 1 |
| Itoh, T; Karashima, T; Kuriyama, H | 1 |
| Bar-Meir, S; Bardan, E; Halpern, Z | 1 |
| Demma, FJ; Wilson, RR | 1 |
| Feely, J; Maclean, D | 1 |
| Boring, S; Chen, J; Johnson, F; Klett, R; Raisfeld-Danse, IH | 1 |
| Fung, HL; Kamiya, A; Sutton, SC | 1 |
| Arsura, E; Greengart, A; Guadagnino, V; Hollander, G; Lichstein, E; Nicchi, V; Sanders, M | 1 |
| Belenkie, I; Kingma, I; Manyari, D; Smiseth, OA; Smith, ER; Tyberg, JV | 1 |
| Thadani, U | 2 |
| Berne, RM; Rubio, R; Tsukada, T | 1 |
| Silberbauer, K; Sinzinger, H; Wirthumer-Hoche, C | 1 |
| Abshagen, U; Dietmann, K; Sponer, G; Strein, K | 1 |
| Richardson, PJ; Timmis, AD | 1 |
| Haase, W; Marten, W; Weiss, M | 1 |
| Inouh, T; Kikuchi, Y; Mizukami, M; Nakamura, M; Tomoike, H; Watanabe, K | 1 |
| Inou, T | 1 |
| Aono, J; Haruta, K; Sakai, K | 1 |
| Hochrein, H; Lehmann, HU | 1 |
| Mukharliamov, NM | 1 |
| Kaltenbach, M | 1 |
| Chatterjee, K; Parmley, WW | 1 |
| Chatterjee, K | 1 |
| Lhoste, F | 1 |
| Baligadoo, S; Chiche, P | 1 |
| Bragina, GI; Komarov, FI; Ol'binskaia, LI | 1 |
| Belinskaia, TF; Martynov, AI | 1 |
| Khomenko, VL; Pomerantsev, VP; Vasiuk, IuA | 1 |
| Franciosa, JA; Pierpont, G | 1 |
| Freeman, WR; Mandel, WJ; Peter, T | 1 |
| Gould, L; Reddy, CV; Singh, BK; Zen, B | 1 |
| Hayes, TS | 1 |
| Dipalma, JR | 1 |
| Deglin, SM; Mandell, HN | 1 |
| Iskandrian, AS; Kotler, MN; Segal, BL | 1 |
| Halawa, B; Kuc, K; Mazurek, W | 1 |
| Armstrong, PW; Marks, GS; Moffat, JA | 1 |
| Bashir, A; Henderson, AH; Lewis, MJ | 1 |
| Bomber, JW; De Tullio, PL | 1 |
| Beck, JK; Kojda, G; Meyer, W; Noack, E | 1 |
| Bron, J; Sterk, GJ; Timmerman, H; van der Werf, JF | 1 |
| Boignon, M; Keefer, LK; Maragos, CM; Morley, D; Wink, DA; Zhang, XY | 1 |
| Kojda, G; Noack, E | 1 |
| Held, P; Olsson, G | 1 |
| Benedini, F; Bertolini, G; Cereda, R; Donà, G; Gromo, G; Levi, S; Mizrahi, J; Sala, A | 1 |
| Fukushima, K; Hirose, T; Ogawa, N; Satoh, T; Suwa, T | 1 |
| Lipicky, RJ; Thadani, U | 1 |
| Cobbe, SM; Conkie, JA; Hutton, I; Oldroyd, KG; Pye, M | 1 |
| Ahlner, J; Torfgård, KE | 1 |
| Opie, LH; Thadani, U | 1 |
| Lipton, SA; Singel, DJ; Stamler, JS | 1 |
| Bauer, JA; Fung, HL | 1 |
| Fehske, W; Honikel, HJ | 1 |
| Anderson, TJ; Ganz, P; Meredith, IT; Selwyn, AP; Yeung, AC | 1 |
| Aldershvile, J; Boesgaard, S; Kjøller-Hansen, L; Laursen, JB; Poulsen, HE | 1 |
| Kojda, G; Meyer, W; Noack, E | 1 |
| Brennan, G; Hayes, R; Johnston, D; McVeigh, G | 1 |
| Iimura, O; Itoya, M; Iwamoto, T; Miura, T; Shimamoto, K; Urabe, K | 1 |
| Snape, JR; White, GF | 1 |
| Harrison, DG | 1 |
| Aldershvile, J; Anderson, ME; Boesgaard, S; Loft, S; Meister, A; Poulsen, HE | 1 |
| Hayes, PC; Jones, AL | 1 |
| Kleist, P | 1 |
| Davies, GJ; Nadazdin, A | 1 |
| Stepin, J | 1 |
| Chen, HS; Choi, YB; Lei, SZ; Lipton, SA; Loscalzo, J; Pan, ZH; Singel, DJ; Stamler, JS; Sucher, NJ | 1 |
| Kinoshita, M; Matsumoto, T; Okamura, T; Toda, N | 1 |
| Channer, KS | 1 |
| Boyer, TD; Harrison, DG; Kurz, MA; Peterson, TE; Whalen, R | 1 |
| Brands, F; Feelisch, M; Kelm, M | 1 |
| Bailey, Y; Dunkley, H; Hamilton, T; Simon, OR; Thomas, E | 1 |
| Bara, A; Busse, R; Mordvintcev, P; Mülsch, A; Vanin, A | 1 |
| Parker, JA | 1 |
| Aldershvile, J; Boesgaard, S; Laursen, JB; Poulsen, HE | 1 |
| Auch-Schwelk, W | 1 |
| Aniya, Y; Ishii, C; Matsuzaki, T; Sakanashi, M; Suenaga, T; Uehara, N; Wada, N | 1 |
| Berdeaux, A; Dubois-Randé, JL; Ghaleh, B; Giudicelli, JF; Hittinger, L | 1 |
| Bergamaschi, M; Gromo, G; Mizrahi, J; Nonaka, K; Ueno, A | 1 |
| Bassenge, E; Cereda, R; Fink, B | 1 |
| Boulanger, CM; Desta, B; Nakashima, M; Vanhoutte, PM | 1 |
| Cremonesi, P; Donà, G; Giuliani, P; Mizrahi, J; Passaro, A; Stella, P; Tursi, F | 1 |
| Aldershvile, J; Boesgaard, S; Busse, R; Gruhn, N; Laursen, JB; Mordvintcev, P; Mülsch, A; Nielsen-Kudsk, JE; Trautner, S | 1 |
| Arai, M; Aso, N; Hama, J; Ishikawa, K; Kamata, N; Kanamasa, K; Katori, Y; Kimura, A; Naito, T; Nakai, S; Ogawa, I; Oyaizu, M; Takenaka, T; Yabushita, H; Yamamoto, K; Yamamoto, T | 1 |
| Lazar, A; Puscas, I; Vlaicu, R | 1 |
| Mazzotta, G | 1 |
| Anggård, EE; Carrier, MJ; Laight, DW | 1 |
| Brodman, BW; Sharma, A; Sundaram, ST; Zhang, YZ | 1 |
| Davletshin, RA; Eliseev, AS; Musina, FS; Nurmukhametova, RA | 1 |
| Gramling-Babb, P; Miller, MJ; Reeves, ST; Roy, RC; Zile, MR | 1 |
| Chirkov, YY; Chirkova, LP; Horowitz, JD | 1 |
| Inobe, Y; Kugiyama, K; Miyagi, H; Ohgushi, M; Takahashi, M; Tomiguchi, S; Yasue, H | 1 |
| Barnes, S; Darley-Usmar, VM; Kirk, M; Moellering, D; Patel, RP; White, CR | 1 |
| Blaise, G; Charbonneau, M; Francoeur, M; Leclerc, G; Salazkin, I; Troncy, E; Vinay, P; Yang, F | 1 |
| Parker, JD; Parker, JO | 1 |
| Kinoshita, M; Liu, Q; Matsumoto, T; Mitsunami, K; Nakae, I; Takahashi, M; Takaoka, A | 1 |
| Kakihana, M; Ohtsuka, S; Sugishita, Y; Watanabe, H | 3 |
| Benjamin, N; Blake, DR; Eisenthal, R; Harrison, R; Millar, TM; Stevens, CR | 1 |
| Hinz, B; Schröder, H | 1 |
| Bassenge, E; Dikalov, S; Grigor'ev, IA; Voinov, M | 1 |
| Bassenge, E; Dikalov, S; Fink, B; Skatchkov, M; Stalleicken, D | 1 |
| Chen, HS; Choi, YB; Lipton, SA; Sucher, NJ | 1 |
| Accashian, JV; Kim, BJ; Smets, BF; Vinopal, RT | 1 |
| Ferdinandy, P; Nemeth, J; Oroszi, G; Szilvassy, Z; Szolcsanyi, J; Tosaki, A | 1 |
| Fukuto, JM; Wong, PS | 1 |
| Byrns, R; Ignarro, LJ; Li, XY; Ma, SX | 1 |
| Borthayre, AB; Harrison, DG; Hink, U; Kurz, S; Münzel, T; Nickenig, G | 1 |
| Chirkov, YY; Chirkova, LP; Holmes, AS; Horowitz, JD | 1 |
| Bassenge, E; Dikalov, S; Fink, B; Skatchkov, M | 1 |
| Bauer, JA; Coyle, CM; Jing, L; Mihm, MJ | 1 |
| Gazewood, JD | 1 |
| Baldassarre, S; Berkenboom, G; Fontaine, D; Fontaine, J; Preumont, N; Unger, P | 1 |
| Werdan, K | 1 |
| Brockman, D; Eis, A; Kossenjans, W; Myatt, L; Sahay, R | 1 |
| Anderson, DJ; Bennett, BM; McGuire, JJ; Ratz, JD | 1 |
| Patel, JC | 1 |
| MacAllister, RJ | 1 |
| Schwinger, RH | 1 |
| Cirino, G; Lovren, F; McKnight, W; Muscará, MN; Triggle, CR; Wallace, JL | 1 |
| Chang, W; Hsiao, G; Lee, C; Lee, LW; Lin, CH; Sheu, JR; Su, CH | 1 |
| Buikema, H; Crijns, HJ; de Zeeuw, D; Monnink, SH; Tio, RA; van Gilst, WH | 1 |
| Daniel, TA; Nawarskas, JJ | 1 |
| Caidahl, K; Petersson, AS; Ringqvist, A; Wennmalm, A | 1 |
| Annuk, M; Fellström, B; Hall, J; Larsson, A; Lind, L; Lithell, H | 1 |
| Bennett, BM; Dringenberg, HC; Reynolds, JN; Smith, S; Thatcher, GR | 1 |
| Freeman, BA; Fukai, T; Harrison, DG; Kurz, S; Laursen, JB; McCann, L; Somers, M; Tarpey, M; Warnholtz, A | 1 |
| Kinoshita, M; Matsumoto, T; Nakae, I; Omura, T; Takahashi, M | 1 |
| Donoghue, JF; Kwek, K; Read, MA; Walters, WA; Zhang, XQ | 1 |
| Leong, SK; Ruan, RS; Yeoh, KH | 1 |
| Dikmen, A; Döndaş, N; Ergün, Y; Oğülener, N | 1 |
| Brown, BJ; Chakraborty, S; Massey, V; Meah, Y | 1 |
| Gupte, SA; Okada, T | 1 |
| Artz, JD; Bennett, BM; Thatcher, GR; Toader, V; Zavorin, SI | 1 |
| Higashi, Y; Kodama, I; Nakagawa, K; Ohama, K; Sakashita, T; Sanada, M; Sasaki, S; Tsuda, M | 1 |
| Funae, Y; Imaoka, S; Inoue, M; Minamiyama, Y; Okada, S; Takemura, S | 1 |
| Fung, HL; Lee, WI; Wang, EQ | 1 |
| Adding, LC; Agvald, P; Artlich, A; Gustafsson, LE; Persson, MG | 1 |
| Fadel, B; Hagan, V; Hastie, T; Heidenreich, PA; Hlatky, MA; Lee, BK; McDonald, KM | 1 |
| Artz, JD; Marletta, MA; McCracken, JL; Schmidt, B | 1 |
| Berk, BC; Fox, RJ; Frame, MD; Kim, D; Mohan, A; Yan, C | 1 |
| Hanspal, IS; Magid, KS; Megson, IL; Webb, DJ | 1 |
| Adachi, H | 1 |
| Kleschyov, A; Mülsch, A; Münzel, T | 1 |
| Devine, AB; Dixon, LJ; Hamilton, P; Hanratty, CG; Leahey, WJ; McGrath, LT; McVeigh, GE; Morgan, DG; Wilson, M | 1 |
| Nicolescu, AC; Reynolds, JN; Thatcher, GR; Turro, NJ; Zavorin, SI | 1 |
| Cadelina, GW; Dudenhoefer, AA; Groszmann, RJ; Gupta, T; Loureiro-Silva, MR | 1 |
| Akrill, P; Cocker, J; Guiver, R | 1 |
| Bennett-Richards, KJ; Bruckdorfer, KR; Deanfield, JE; Donald, AE; Kattenhorn, M; Oakley, GR; Rees, L; Varghese, Z | 1 |
| Bennett, BM; Boegman, RJ; Dumitrascu, A; Jhamandas, K; Ratz, JD; Reynolds, JN; Scutaru, D; Thatcher, GR; Zavorin, SI | 1 |
| Chayama, K; Higashi, Y; Kimura, M; Kodama, I; Nakagawa, K; Ohama, K; Sanada, M; Tsuda, M | 1 |
| Cieśliński, A; Grajek, S; Grygier, M; Mularek-Kubzdela, T; Seniuk, W | 1 |
| Hiraoka, K; Inoue, T; Ishigami, Y; Izumi, M; Nakanishi, T; Otaki, Y; Takamitsu, Y | 1 |
| Akrill, P; Cocker, J | 1 |
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| Hirai, N; Kajiwara, I; Kawano, H; Miyamoto, S; Nakamura, H; Ogawa, H; Sakamoto, T; Shimomura, H; Soejima, H; Yasue, H; Yodoi, J; Yoshimura, M | 1 |
| GERSTNER, K | 1 |
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| Amado, JA; Bustamante, M; de Berrazueta, JR; Garcia-Unzueta, MT; Llorca, J; Sampedro, I | 1 |
| Bennett, BM; DiFabio, J; Ji, Y; Thatcher, GR; Vasiliou, V | 1 |
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| BURGISON, RM; CARR, CJ; FASSELL, MS; KRANTZ, JC | 1 |
| HUMPHREYS-JONES, JF; STEPHENSON, D | 1 |
| CRITCHLOW, JK; HOLM, LW; JOHNSON, LF | 1 |
| Cittadino, M; Moreno, H; Sabha, M; Sousa, MG; Tácito, LH; Tanus-Santos, JE; Yugar-Toledo, JC | 1 |
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| Bajza, A; Literati-Nagy, P; Nemeth, J; Peitl, B; Porszasz, R; Rabloczky, G; Szilvassy, J; Szilvassy, Z | 1 |
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| Bennett, BM; Nicolescu, AC; Thatcher, GR; Toader, V | 1 |
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| Hai, S; Hirohashi, K; Minamiyama, Y; Okada, S; Takemura, S; Yamasaki, K | 1 |
| Ciaponi, M; Fini, M; Gambacciani, M; Genazzani, AR; Mercuro, G; Monteleone, P; Rosano, GM; Silvestri, A; Vitale, C | 1 |
| Aulaskari, P; Haukka, M; Kotikoski, H; Moilanen, E; Oksala, O; Oresmaa, L; Pohjala, E; Salminen, J; Vainiotalo, P; Vapaatalo, H | 1 |
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| Bode-Böger, SM; Kojda, G | 1 |
| Christopher, TA; Fan, Q; Gao, F; Lopez, BL; Ma, XL; Zhang, L | 1 |
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| Anderson, RA; Chirkov, YY; Ellis, GR; Evans, LM; Frenneaux, MP; Horowitz, JD; Jackson, SK; Lewis, MJ; Morris, K; Rees, A | 1 |
| Hai, S; Minamiyama, Y; Okada, S; Suehiro, S; Takemura, S | 1 |
| Acikgoz, N; Aksoy, Y; Akturk, E; Bariskaner, E; Sivri, N; Turhan, H; Yetkin, E | 1 |
| Rodgers, T; Thadani, U | 1 |
| Bügel, S; Ferrari, M; Hallund, J; Kjaer, A; Teerlink, T; Tetens, I; Tholstrup, T; Wiinberg, N | 1 |
| Brandt, M; Bruns, K; Daiber, A; Hink, U; Isse, T; Kawamoto, T; Kleschyov, AL; Lackner, KJ; Lange, K; Lehmann, J; Münzel, T; Oelze, M; Schulz, E; Seeling, A; Steinhoff, L; Weiner, H; Wenzel, P | 1 |
| Khodosovskii, MN; Zinchuk, VV | 1 |
| Bajerová, P; Eisner, A; Jezová, V; Skládal, J; Ventura, K | 1 |
| Fukudome, T; Hamasaki, S; Ichiki, H; Ichiki, T; Ishida, S; Kataoka, T; Kubozono, T; Mizoguchi, E; Ninomiya, Y; Ogawa, M; Oketani, N; Okui, H; Orihara, K; Saihara, K; Shinsato, T; Tei, C | 1 |
| Di Stolfo, G; Dragoni, S; Forconi, S; Gori, T; Leone, MC; Lisi, M; Parker, JD | 1 |
| Beretta, M; Mayer, B | 1 |
| Beuve, A; Durán, WN; Fioramonti, X; Iwahashi, T; Kim, DD; Sayed, N | 1 |
| D'Alonzo, L; Favale, S; Forleo, C; Guida, P; Iacoviello, M; Sorrentino, S | 1 |
| Daiber, A; Jansen, T; Münzel, T; Oelze, M; Schuhmacher, S; Wenzel, P | 1 |
| Münzel, T | 1 |
| Anusevicius, Z; Cenas, N; Nivinskas, H; Sarlauskas, J; Scrutton, NS; Toogood, HS | 1 |
| Daiber, A; Gori, T | 1 |
| Chegaev, K; Di Stilo, A; Fruttero, R; Gasco, A; Lazzarato, L; Marcarino, P; Roussel, C; Vanthuyne, N | 1 |
| Kosmicki, MA | 1 |
| Gori, T; Lisi, M; Parker, JD | 1 |
| Daiber, A; Kawamoto, T; König, A; Lange, K; Lehmann, J; Münzel, T; Oelze, M; Roegler, C; Schuhmacher, S; Schulz, E; Sydow, L; Wenzel, P | 1 |
| Miller, MR; Wadsworth, RM | 1 |
| Bauersachs, J | 1 |
| Chen, ZQ; Hong, WL; Hu, RZ; Xu, SY; Yi, JH; Zhang, LY; Zhao, FQ | 1 |
| Csont, T | 1 |
| Cooper, C; de Boer, A; de Vries, F; Lalmohamed, A; Leufkens, HG; Pouwels, S; Rejnmark, L; Souverein, P; van Staa, T; Vestergaard, P | 1 |
| HUMPHREYS, RJ; RAAB, W | 1 |
| Balducci, C; De Pascalis, F; Favale, S; Forleo, C; Guida, P; Iacoviello, M; Puzzovivo, A; Rodio, M; Sarlo, M; Sorrentino, S | 1 |
| Harada, E; Kuboyama, O; Mizuno, Y; Morikawa, Y; Yasue, H; Yoshimura, M | 1 |
| Daiber, A; Gori, T; Münzel, T | 1 |
| Glusa, E; König, A; Lehmann, J; Roegler, C | 1 |
| Fadel, PJ; Farias Iii, M; Gallagher, KM; Thomas, GD; Wang, Z | 1 |
| Ampleman, G; Bordeleau, G; Lévesque, R; Marois, A; Martel, R; Thiboutot, S | 1 |
| Akopova, OV; Kolchyns'ka, LI; Korkach, IuP; Kotsiuruba, AV; Sagach, VF | 1 |
| Furdui, CM; Gorren, AC; Gruber, K; Lang, BS; Mayer, B; Oberdorfer, G; Poole, LB; Wenzl, MV | 1 |
| Del Rosso, A; Marchionni, N; Morrione, A; Rafanelli, M; Ungar, A | 1 |
| Brooks, SC; Diercks, DB; Fermann, GJ; Kidney, R; McCabe, A; Pospisil, C; Salter, N; Seupaul, RA; Wakai, A | 1 |
| Bucur, RC; Cummings, SR; Hamilton, CJ; Jamal, SA; Reid, LS | 1 |
| Fung, HL; Fung, SM; Lin, S; Page, NA | 1 |
| Kobayashi, J; Kobayashi, M; Kubo, Y; Natsume, H; Ohtake, K; Sonoda, K; Uchida, H; Uchida, M | 1 |
| Du, Y; Lei, S; Liu, H; Qiao, X; Su, W; Xia, Z; Xia, ZY; Xu, J; Yang, QJ; Zhang, L | 1 |
| Braga, VA; França-Silva, MS; Guimarães, DD; Mendes-Júnior, LG; Nalivaiko, E; Queiroz, TM | 1 |
| Brett, S; Chowienczyk, P; Clapp, B; Fok, H; Guilcher, A; Li, Y; Shah, A | 1 |
| Amigo, JM; de la Ossa, MÁ; García-Ruiz, C | 1 |
| Carresi, C; Dagostino, C; Giancotti, LA; Gliozzi, M; Gratteri, S; Malara, N; Mollace, V; Muscoli, C; Muscoli, S; Musolino, V; Palma, E; Romeo, F; Sacco, I; Salvemini, D; Visalli, V; Vitale, C | 1 |
| Goto, T; Matsui, M; Miyata, S; Momomura, S; Nihei, T; Odaka, Y; Ogawa, H; Seki, A; Shimokawa, H; Sueda, S; Sumiyoshi, T; Takagi, Y; Takahashi, J; Tanabe, Y; Tsunoda, R; Yasuda, S | 1 |
| Imamura, T; Iwasaki, H; Okamura, T; Shimosato, T; Tawa, M | 1 |
| Herrero-Puente, P; Jacob, J; Llorens, P; Lucas-Imbernón, FJ; Martín-Sánchez, FJ; Martínez-Camblor, P; Martínez-Zapico, A; Miró, Ò; Vázquez-Álvarez, J | 1 |
| Daiber, A; Hausding, M; Jabs, A; Jansen, T; Kopp, M; Kröller-Schön, S; Mikhed, Y; Münzel, T; Oelze, M; Schulz, E; Stamm, P; Stasch, JP; Steven, S; Welschof, P | 1 |
| Giuseppe, C; Hans-Ulrich, I; Paul, J | 1 |
| Gjurcevic, E; Ivkic, G; Klaric, MŠ; Kovacić, S; Rumora, L | 1 |
| Axton, ER; Hardardt, EA; Stevens, JF | 1 |
| Akopova, O; Gavenauskas, B; Kolchinskaya, L; Korkach, Y; Kotsiuruba, A; Mankovska, I; Nosar, V; Sagach, V; Serebrovska, Z | 1 |
| Barron, L; de la Ossa, MÁF; García-Ruiz, C; Gilchrist, E; Zapata, F | 1 |
| Park, JS; Seo, KW; Shin, JH; Tahk, SJ | 1 |
| Eroglu, E; Fassett, JT; Gorren, ACF; Graier, WF; Kollau, A; Malli, R; Mayer, B; Opelt, M; Schrammel, A; Waldeck-Weiermair, M; Wölkart, G | 1 |
| Bai, YP; Jian, X; Li, P; Liu, C; Lu, JX; Miao, Z; Pan, GP; Pang, XY; Ping, S; Shan, MR; Wang, SX; Wang, XQ; Zhou, SN | 1 |
| Chokshi, AB; Desai, PR; Mehta, PJ | 1 |
| Cha, J; Ha, M; Hwang, SH; Kang, EY; Kim, C; Kim, W; Lee, KY; Lee, SH; Oh, YW; Park, SJ; Yong, HS | 1 |
| Surdacki, A; Tsikas, D | 1 |
| An, GP; Dong, B; Han, SF; Jin, Q; Li, XY; Lin, YM; Liu, MY; Meng, LB; Song, Y; Wang, SX; Zhang, HM | 1 |
| Brandes, RP; Daiber, A; Ding, X; Gajos-Draus, A; Lopez, M; Lundberg, JO; Malacarne, PF; Offermanns, S; Rezende, F | 1 |
| Bailey, J; Hawks, MK; Malu, OO | 1 |
| Liu, W; Meng, Z; Wang, G | 1 |
| Bhindi, R; Ekmejian, AA; Figtree, GA | 1 |
| Akhtar, MF; Khan, MI; Riaz, A; Saleem, A; Sharif, H; Sharif, Z | 1 |
| Du, F; Fan, H; Ren, L; Yang, X; Yuan, W; Zhang, L; Zhang, Y | 1 |
| Campos-Toimil, M; Gil-Longo, J; Matos, MJ; Picos, A; Seoane, N; Uriarte, E | 1 |
| Cheng, Z; Ding, Y; Gao, J; Geng, X; Jiang, S; Rajah, GB; Wehbe, A; Wills, M | 1 |
| Bosco, F; Cardamone, A; Carresi, C; Coppoletta, A; Gliozzi, M; Macrì, R; Maiuolo, J; Mollace, R; Mollace, V; Muscoli, C; Musolino, V; Oppedisano, F; Palma, E; Scarano, F | 1 |
| Cummings, SR; Ganz, P; Gibson, CJ; Grady, D; Huang, AJ; Raghunathan, H; Schembri, M; Vittinghoff, E | 1 |
109 review(s) available for nitrates and nitroglycerin
| Article | Year |
|---|---|
[Molsidomin compared to nitrates. Use in patients with manifest coronary disease].
Topics: Adrenergic beta-Antagonists; Aged; Calcium; Coronary Disease; Drug Evaluation; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Morpholines; Nitrates; Nitroglycerin; Oxadiazoles; Sydnones | 1979 |
Antianginal drugs.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anabolic Agents; Angina Pectoris; Animals; Antithyroid Agents; Arteriosclerosis; Calcium; Cardiac Glycosides; Coronary Circulation; Coronary Disease; Delayed-Action Preparations; Hemodynamics; Humans; Hypoxia; Neurotransmitter Agents; Nitrates; Nitroglycerin; Sympathomimetics; Vasodilator Agents | 1979 |
Nitroglycerin and nitrate esters.
Topics: Angina Pectoris; Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Esters; Heart Failure; Hemodynamics; Humans; Mouth Floor; Myocardial Contraction; Myocardial Infarction; Nitrates; Nitroglycerin; Time Factors | 1978 |
Clinical use of nitrates. I. Nitrates as antianginal drugs.
Topics: Angina Pectoris; Coronary Circulation; Hemodynamics; Humans; Nitrates; Nitroglycerin | 1979 |
[Use of vasodilator agents in circulatory insufficienty].
Topics: Blood Circulation; Dihydralazine; Heart Failure; Humans; Hydralazine; Nitrates; Nitroglycerin; Nitroprusside; Prazosin; Quinazolines; Vasodilator Agents | 1979 |
Occupational habituation to aliphatic nitrates and the withdrawal hazards of coronary disease and hypertension.
Topics: Animals; Coronary Disease; Environmental Exposure; Humans; Hypertension; Nitrates; Nitroglycerin; Occupational Diseases; Substance Withdrawal Syndrome | 1977 |
Vasodilator therapy of cardiac failure: (first of two parts).
Topics: Blood Vessels; Diuretics; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Hydralazine; Nitrates; Nitroglycerin; Nitroprusside; Phentolamine; Trimethaphan; Vasodilator Agents | 1977 |
Organic nitrate metabolism.
Topics: Animals; Biodegradation, Environmental; Dogs; Guinea Pigs; Humans; In Vitro Techniques; Isosorbide Dinitrate; Mice; Nitrates; Nitroglycerin; Oxidoreductases; Pentaerythritol Tetranitrate; Propylene Glycols; Rats; Time Factors | 1976 |
[The nitrate withdrawal syndrome. A review of the literature and the data from the authors' own research].
Topics: Angina Pectoris; Electrocardiography; Exercise Test; Humans; Nitrates; Nitroglycerin; Physical Exertion; Substance Withdrawal Syndrome; Time Factors | 1992 |
Pharmacologic treatment of portal hypertension.
Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Metoclopramide; Molsidomine; Nitrates; Nitroglycerin; Serotonin Antagonists; Somatostatin; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 1992 |
Daily life ischemia and nitrate therapy.
Topics: Activities of Daily Living; Administration, Cutaneous; Administration, Sublingual; Animals; Coronary Disease; Drug Administration Schedule; Drug Tolerance; Humans; Nitrates; Nitroglycerin; Oxygen Consumption | 1992 |
Role of nitrates in unstable angina pectoris.
Topics: Acetylcysteine; Angina, Unstable; Drug Therapy, Combination; Humans; Nitrates; Nitroglycerin | 1992 |
[Tolerance in treatment with nitrates].
Topics: Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Risk Factors | 1992 |
Response of coronary arteries to nitrates, the EDRF-donor SIN-1, and calcium antagonists.
Topics: Calcium Channel Blockers; Coronary Vasospasm; Coronary Vessels; Humans; Molsidomine; Nitrates; Nitroglycerin; Vasodilation | 1991 |
Stable angina pectoris: 3. Medical treatment.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Agents; Cardiovascular Diseases; Drug Interactions; Humans; Nitrates; Nitroglycerin | 1990 |
Relationship between the inhibition of receptor-induced increase in cytosolic free calcium concentration and the vasodilator effects of nitrates in patients with congestive heart failure.
Topics: Adult; Blood Platelets; Calcium; Heart Failure; Humans; Isosorbide Dinitrate; Middle Aged; Nifedipine; Nitrates; Nitroglycerin; Nitroprusside; Plethysmography | 1990 |
Development of long-acting nitrate delivery systems.
Topics: Administration, Cutaneous; Administration, Oral; Angina Pectoris; Delayed-Action Preparations; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1990 |
Nitrate tolerance. A problem during continuous nitrate administration.
Topics: Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Exercise; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1990 |
Nitrates: why and how should they be used today? Current status of the clinical usefulness of nitroglycerin, isosorbide dinitrate and isosorbide-5-mononitrate.
Topics: Angina Pectoris; Coronary Disease; Delayed-Action Preparations; Drug Administration Schedule; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1990 |
[Nitrates in the treatment of heart failure].
Topics: Dose-Response Relationship, Drug; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1990 |
Angina: evolution of the role of nitrates.
Topics: Angina Pectoris; Exercise Test; Humans; Nitrates; Nitroglycerin; Randomized Controlled Trials as Topic | 1990 |
Mechanisms of nitrate tolerance: a review.
Topics: Drug Tolerance; Humans; Nitrates; Nitroglycerin; Vasodilator Agents | 1990 |
Mechanisms of nitrate tolerance--influence of the metabolic activation pathways.
Topics: Animals; Biotransformation; Coronary Disease; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1990 |
Intermittent nitrate therapy in angina pectoris.
Topics: Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Methods; Nitrates; Nitroglycerin | 1989 |
[Is it possible to prevent the phenomenon of tolerance in patients with angina pectoris treated with nitrates?].
Topics: Angina Pectoris; Clinical Protocols; Double-Blind Method; Drug Tolerance; Humans; Male; Nitrates; Nitroglycerin | 1989 |
Endothelium-derived nitric oxide: pharmacology and relationship to the actions of organic nitrate esters.
Topics: Animals; Humans; Nitrates; Nitric Oxide; Nitroglycerin; Vasodilator Agents | 1989 |
[The mechanism of action of nitrates, 1988 status].
Topics: Angina Pectoris; Animals; Coronary Disease; Endothelium, Vascular; Hemodynamics; Humans; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Vascular Resistance | 1989 |
[Transdermal forms of nitrates].
Topics: Administration, Cutaneous; Angina Pectoris; Delayed-Action Preparations; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1989 |
Effect of intravenous nitrates on mortality in acute myocardial infarction: an overview of the randomised trials.
Topics: Clinical Trials as Topic; Evaluation Studies as Topic; Follow-Up Studies; Humans; Infusions, Intravenous; Myocardial Infarction; Nitrates; Nitroglycerin; Nitroprusside; Random Allocation; Statistics as Topic; Time Factors | 1988 |
Nitrate tolerance.
Topics: Angina Pectoris; Drug Tolerance; Hemodynamics; Humans; Male; Nitrates; Nitroglycerin; Time Factors | 1986 |
Tolerance to organic nitroesters in experimental animals. An assessment of in vitro and in vivo investigations.
Topics: Animals; Drug Tolerance; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin | 1986 |
The use of invasive techniques to study circulatory effects of nitrates.
Topics: Cardiac Catheterization; Hemodynamics; Humans; Nitrates; Nitroglycerin | 1986 |
Relationship between pharmacokinetics and pharmacodynamics of organic nitrates.
Topics: Angina Pectoris; Dose-Response Relationship, Drug; Drug Tolerance; Hemodynamics; Humans; Isosorbide Dinitrate; Kinetics; Nitrates; Nitroglycerin | 1986 |
Pharmacokinetics of various preparations of organic nitrates.
Topics: Delayed-Action Preparations; Humans; Isosorbide Dinitrate; Kinetics; Nitrates; Nitroglycerin | 1987 |
Treatment of acute anginal attacks with nitrates.
Topics: Administration, Oral; Angina Pectoris; Humans; Nitrates; Nitroglycerin | 1987 |
Tolerance to organic nitrates in ischemic heart disease.
Topics: Coronary Disease; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1987 |
Glyceryl trinitrate (nitroglycerin) and the organic nitrates. Choosing the method of administration.
Topics: Angina Pectoris; Heart Failure; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitroglycerin | 1987 |
Controversies in the use of transdermal nitroglycerin systems.
Topics: Administration, Topical; Coronary Disease; Dose-Response Relationship, Drug; Heart Failure; Hemodynamics; Humans; Nitrates; Nitroglycerin | 1987 |
Nitrates.
Topics: Animals; Cardiovascular Diseases; Coronary Disease; Heart Failure; Humans; Nitrates; Nitroglycerin | 1988 |
Nitrate therapy for angina pectoris. Current concepts about mechanism of action and evaluation of currently available preparations.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Angina, Unstable; Animals; Coronary Vasospasm; Delayed-Action Preparations; Drug Tolerance; Hemodynamics; Humans; Infusions, Parenteral; Nitrates; Nitroglycerin; Substance-Related Disorders; Time Factors | 1985 |
Efficacy of different forms of nitrates in angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Calcium; Drug Tolerance; Humans; Isosorbide Dinitrate; Kinetics; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Nucleotides, Cyclic; Ointments; Vasodilation | 1985 |
Pharmacology of nitroglycerin and long-acting nitrates.
Topics: Absorption; Administration, Oral; Administration, Topical; Angina Pectoris; Animals; Cheek; Delayed-Action Preparations; Drug Tolerance; Heart Failure; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Kinetics; Mouth Floor; Mouth Mucosa; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Vasodilator Agents | 1985 |
Nitrate formulations and drug delivery systems--an overview.
Topics: Animals; Biological Availability; Drug Tolerance; Isosorbide Dinitrate; Kinetics; Nitrates; Nitroglycerin; Rats | 1985 |
Pharmacological therapy of angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arteriosclerosis; Coronary Circulation; Coronary Disease; Humans; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Propranolol | 1973 |
Editorial: Nitrates in the prophylactic treatment of angina pectoris.
Topics: Angina Pectoris; Exercise Test; Heart; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1973 |
Angina pectoris: diagnosis, evaluation and therapy.
Topics: Angina Pectoris; Angiography; Digitalis Glycosides; Ethanol; Female; Heart Function Tests; Humans; Male; Myocardium; Nitrates; Nitroglycerin; Obesity; Oxygen Consumption; Phenobarbital; Propranolol; Smoking | 1973 |
Management of stable angina.
Topics: Administration, Oral; Angina Pectoris; Animals; Coronary Circulation; Delayed-Action Preparations; Digitalis Glycosides; Diuretics; Dogs; Heart; Humans; Mouth Floor; Myocardium; Nitrates; Nitrites; Nitroglycerin; Oxygen Consumption; Propranolol; Tranquilizing Agents; Vasodilator Agents | 1973 |
Organic nitrates in angina pectoris.
Topics: Administration, Oral; Amyl Nitrite; Angina Pectoris; Blood Pressure; Coronary Circulation; Drug Tolerance; Heart Rate; Humans; Isosorbide Dinitrate; Mouth Floor; Muscle Contraction; Nitrates; Nitroglycerin; Oxygen Consumption; Physical Exertion; Vasodilator Agents | 1972 |
Aspects of nitrate ester metabolism.
Topics: Animals; Blood; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Colorimetry; Dogs; Esters; Glutathione Reductase; Glycogen; Glycols; Kidney; Kinetics; Liver; Mice; Monoamine Oxidase Inhibitors; Nitrates; Nitrites; Nitroglycerin; Oxidoreductases; Pentaerythritol Tetranitrate; Rats | 1971 |
Some pharmacological properties of organic nitrates.
Topics: Angina Pectoris; Animals; Arterioles; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Drug Tolerance; Humans; Inactivation, Metabolic; Isosorbide Dinitrate; Liver; Muscle, Smooth, Vascular; Myocardium; Nitrates; Nitroglycerin; Oxyhemoglobins; Vasodilation; Venous Pressure | 1984 |
Medical management of patients with chronic stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Chronic Disease; Clinical Laboratory Techniques; Digitalis Glycosides; Diuretics; Drug Therapy, Combination; Exercise Therapy; Female; Heart; Hemodynamics; Humans; Male; Medical History Taking; Middle Aged; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Physical Examination; Risk | 1980 |
Myocardial infarct size. Part 2. Comparison of anti-infarct effects of beta-blockade, glucose-insulin-potassium, nitrates, and hyaluronidase.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Glucose; Heart Rate; Heparin; Humans; Hyaluronoglucosaminidase; Hyperglycemia; Insulin; Myocardial Infarction; Nitrates; Nitroglycerin; Nitroprusside; Potassium; Propranolol; Time Factors | 1980 |
[Effect of nitrates, nitrate-like substances, calcium antagonists and beta-adrenergic receptor blockers on peripheral circulation].
Topics: Adrenergic beta-Antagonists; Amyl Nitrite; Angina Pectoris; Animals; Blood Circulation; Calcium Channel Blockers; Humans; Isosorbide Dinitrate; Molsidomine; Muscle Contraction; Muscles; Nitrates; Nitroglycerin; Nitroprusside; Rats; Sydnones | 1982 |
The transdermal administration of nitrates: an overview.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Blood Pressure; Coronary Disease; Exercise Test; Heart Failure; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Nitroprusside; Ointments; Patient Compliance | 1983 |
Pharmacokinetic determinants of nitrate action.
Topics: Angina Pectoris; Humans; In Vitro Techniques; Kinetics; Liver; Nitrates; Nitroglycerin; Vascular Resistance | 1984 |
Nitrate delivery systems in perspective. A decade of progress.
Topics: Administration, Intranasal; Administration, Oral; Administration, Topical; Angina Pectoris; Heart Failure; Humans; Infusions, Parenteral; Kinetics; Myocardial Infarction; Nitrates; Nitroglycerin; Ointments; Time Factors | 1984 |
Nitrate tolerance and dependence.
Topics: Ambulatory Care; Angina Pectoris; Animals; Cardiovascular Diseases; Dogs; Drug Tolerance; Heart Failure; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Occupational Medicine; Propranolol; Rabbits; Rats; Substance-Related Disorders; Time Factors | 1980 |
Nitroglycerin and long-acting nitrates.
Topics: Administration, Oral; Coronary Circulation; Coronary Disease; Delayed-Action Preparations; Drug Tolerance; Heart; Heart Failure; Humans; Liver; Myocardial Infarction; Nitrates; Nitroglycerin; Vasodilation | 1980 |
Vasodilator therapy for chronic heart failure.
Topics: Captopril; Chronic Disease; Heart Failure; Hemodynamics; Humans; Hydralazine; Nitrates; Nitroglycerin; Physical Exertion; Prazosin; Vasodilator Agents | 1980 |
[Peripheral vasodilator agents in cardiology].
Topics: Clinical Trials as Topic; Coronary Vessels; Heart Failure; Hemodynamics; Humans; Hydralazine; Myocardial Infarction; Nitrates; Nitroglycerin; Nitroprusside; Phentolamine; Piperazines; Prazosin; Quinazolines; Vasodilator Agents | 1980 |
Cardiovascular clinical pharmacology of impedance reducing agents.
Topics: Heart Failure; Humans; Hydralazine; Nitrates; Nitroglycerin; Nitroprusside; Phentolamine; Prazosin; Vasodilator Agents | 1981 |
Oral nitrate preparations: an update.
Topics: Administration, Oral; Dosage Forms; Drug Tolerance; Humans; Nitrates; Nitroglycerin | 1995 |
Short and long-acting oral nitrates for stable angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Delayed-Action Preparations; Drug Therapy, Combination; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; United States; United States Food and Drug Administration; Vasodilator Agents | 1994 |
Clinical pharmacokinetics of nitrates.
Topics: Angina Pectoris; Delayed-Action Preparations; Drug Administration Routes; Half-Life; Humans; Isosorbide Dinitrate; Liver; Nitrates; Nitroglycerin; Structure-Activity Relationship; Vasodilation; Vasodilator Agents | 1994 |
Mechanisms of action of nitrates.
Topics: Angina Pectoris; Blood Platelets; Cyclic GMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Esterases; Glutathione Transferase; Heart; Heart Failure; Humans; Isosorbide Dinitrate; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Infarction; Nitrates; Nitroglycerin; Oxygen Consumption; Structure-Activity Relationship; Vasodilator Agents | 1994 |
Nitrates for unstable angina.
Topics: Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Angina, Unstable; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Circulation; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Guidelines as Topic; Injections, Intravenous; Myocardial Infarction; Myocardial Ischemia; Nitrates; Nitroglycerin; Oxygen Consumption; Vasoconstriction; Vasodilation | 1994 |
Nitric oxide in the central nervous system.
Topics: Animals; Calcium; Cells, Cultured; Central Nervous System; Cysteine; Neurons; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxidation-Reduction; Oxidative Stress; Receptors, N-Methyl-D-Aspartate; S-Nitrosothiols; Superoxides | 1994 |
Nitrates and nitrate tolerance in congestive heart failure.
Topics: Animals; Drug Tolerance; Heart Failure; Hemodynamics; Humans; Myocardial Infarction; Neurotransmitter Agents; Nitrates; Nitric Oxide; Nitroglycerin; Ventricular Function, Left | 1993 |
Mechanisms of nitrate tolerance.
Topics: Angina Pectoris; Animals; Drug Administration Routes; Drug Therapy, Combination; Drug Tolerance; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Sulfhydryl Compounds; Vascular Resistance | 1994 |
Nitric oxide and nitrovasodilators: similarities, differences and potential interactions.
Topics: Animals; Blood Platelets; Endothelium, Vascular; Humans; Nitrates; Nitric Oxide; Nitroglycerin; Vasodilator Agents | 1994 |
[Nitroglycerin preparations. Effect and tolerance].
Topics: Drug Tolerance; Humans; Nitrates; Nitroglycerin | 1994 |
Nitrate therapy and the development of tolerance.
Topics: Angina Pectoris; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilator Agents | 1993 |
Microbial cleavage of nitrate esters: defusing the environment.
Topics: Biodegradation, Environmental; Collodion; Environmental Microbiology; Environmental Pollutants; Ethylene Glycols; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate | 1993 |
[Endogenous and therapeutic nitrates in healthy and arteriosclerotic blood vessels].
Topics: Animals; Coronary Artery Disease; Endothelium, Vascular; Free Radicals; Humans; Nitrates; Nitric Oxide; Nitroglycerin; Superoxides | 1993 |
Organic nitrates in portal hypertension.
Topics: Animals; Collateral Circulation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Isosorbide Dinitrate; Liver Circulation; Liver Cirrhosis; Nitrates; Nitroglycerin; Vasodilator Agents | 1994 |
Organic nitrates: new formulations and their clinical advantages.
Topics: Cardiovascular Diseases; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Randomized Controlled Trials as Topic | 1996 |
[Use of nitrates in coronary heart disease including acute myocardial infarct].
Topics: Coronary Disease; Hemodynamics; Humans; Multicenter Studies as Topic; Muscle, Smooth, Vascular; Myocardial Infarction; Nitrates; Nitroglycerin; Randomized Controlled Trials as Topic; Vasodilator Agents | 1996 |
[Effectiveness, tolerance, adverse effects of prolonged therapy with nitrate compounds].
Topics: Drug Tolerance; Heart Failure; Humans; Nitrates; Nitroglycerin; Treatment Outcome; Vasodilator Agents | 1996 |
Nitrate therapy for stable angina pectoris.
Topics: Angina Pectoris; Drug Therapy, Combination; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Vasodilator Agents | 1998 |
Neuroprotective versus neurodestructive effects of NO-related species.
Topics: Animals; Central Nervous System; Down-Regulation; Ion Channels; Neurons; Neuroprotective Agents; Neurotoxins; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Oxidation-Reduction; Receptors, N-Methyl-D-Aspartate; Superoxides | 1998 |
[Emergency treatment of acute heart failure].
Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Analgesics, Opioid; Angioplasty, Balloon, Coronary; Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiac Glycosides; Defibrillators, Implantable; Diuretics; Emergencies; Furosemide; Heart Failure; Humans; Morphine; Myocardial Infarction; Nitrates; Nitroglycerin; Pacemaker, Artificial; Prognosis; Pulmonary Edema; Respiration, Artificial; Risk Factors; Shock, Cardiogenic; Time Factors; Vasodilator Agents; Ventricular Dysfunction, Right | 1999 |
Use of nitrate in angina.
Topics: Angina Pectoris; Drug Administration Routes; Humans; Nitrates; Nitroglycerin; Treatment Outcome; Vasodilator Agents | 1999 |
Vitamin C in the prevention of nitrate tolerance.
Topics: Antioxidants; Ascorbic Acid; Drug Tolerance; Hemodynamics; Humans; Nitrates; Nitroglycerin; Vasodilator Agents | 2000 |
An evaluation of beta-blockers, calcium antagonists, nitrates, and alternative therapies for stable angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Complementary Therapies; Evidence-Based Medicine; Humans; Nifedipine; Nitrates; Nitroglycerin; Treatment Outcome; Vasodilator Agents | 1999 |
After 130 years, the molecular mechanism of action of nitroglycerin is revealed.
Topics: Animals; Biotransformation; Cell Line; Mitochondria; Nitrates; Nitric Oxide Donors; Nitrites; Nitroglycerin; Oxidoreductases; Vasodilator Agents | 2002 |
The puzzle of nitrate tolerance: pieces smaller than we thought?
Topics: Animals; Autonomic Nervous System; Blood Vessels; Cardiovascular Diseases; Drug Tolerance; Endothelium, Vascular; Free Radicals; Humans; Nitrates; Nitroglycerin; Vasodilator Agents | 2002 |
How to use nitrates.
Topics: Dose-Response Relationship, Drug; Humans; Nitrates; Nitroglycerin; United States; Vasodilator Agents | 2002 |
Nitrate stimulated tilt table testing: a review of the literature.
Topics: Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Reproducibility of Results; Syncope, Vasovagal; Tilt-Table Test; Vasodilator Agents | 2003 |
CORONARY VASOMOTOR RESPONSE TO PHARMACOLOGIC AGENTS.
Topics: Angina Pectoris; Catecholamines; Coronary Vessels; Heart; Humans; Nitrates; Nitroglycerin; Vasodilator Agents; Vasomotor System | 1964 |
Mechanisms of nitrate tolerance: potential roles of folate.
Topics: Drug Tolerance; Folic Acid; Humans; Nitrates; Nitroglycerin; Oxidative Stress; Vasodilator Agents | 2003 |
Nitrates and NO release: contemporary aspects in biological and medicinal chemistry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Cations; Cyclic GMP; Drug Design; Drug Tolerance; Endothelium, Vascular; Free Radicals; Guanylate Cyclase; Humans; Molecular Structure; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroglycerin; Oxidation-Reduction; Sulfhydryl Compounds; Vasodilator Agents | 2004 |
Cardioprotective effects of glyceryl trinitrate: beyond vascular nitrate tolerance.
Topics: Animals; Blood Vessels; Cardiotonic Agents; Heart; Humans; Myocardial Reperfusion Injury; Nitrates; Nitroglycerin; Vasodilator Agents | 2005 |
[Nitrates. The place in contemporary therapy of ischemic heart disease].
Topics: Angina Pectoris; Contraindications; Delayed-Action Preparations; Humans; Isosorbide Dinitrate; Myocardial Infarction; Myocardial Ischemia; Nitrates; Nitroglycerin; Time Factors; Vasodilator Agents | 2005 |
Organic nitrates in cardiovascular disease.
Topics: Angina, Unstable; Animals; Cardiovascular Diseases; Cyclic GMP; Enalapril; Endothelium, Vascular; Hemodynamics; Humans; Myocardial Infarction; Nitrates; Nitric Oxide; Nitroglycerin; Platelet Aggregation | 2005 |
Pharmacological advancements in the treatment of chronic anal fissure.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Albuterol; Botulinum Toxins; Calcium Channel Blockers; Carbachol; Central Nervous System Agents; Cholinergic Agonists; Chronic Disease; Complementary Therapies; Diltiazem; Drug Administration Schedule; Fissure in Ano; Humans; Indoramin; Nitrates; Nitroglycerin; Randomized Controlled Trials as Topic | 2005 |
Side effects of using nitrates to treat angina.
Topics: Angina Pectoris; Coronary Disease; Drug Interactions; Headache; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Phosphodiesterase Inhibitors; Randomized Controlled Trials as Topic; Syncope; Vasodilator Agents | 2006 |
The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and troubles.
Topics: Animals; Biotransformation; Drug Tolerance; Humans; Nitrates; Nitroglycerin; United States | 2008 |
Mitochondrial aldehyde dehydrogenase (ALDH-2)--maker of and marker for nitrate tolerance in response to nitroglycerin treatment.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Drug Tolerance; Humans; Mitochondria; Nitrates; Nitroglycerin; Oxidative Stress | 2009 |
[Recent findings on nitrates: their action, bioactivation and development of tolerance].
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Coronary Disease; Drug Tolerance; Endothelium, Vascular; Guanylate Cyclase; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Oxidative Stress; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Vasodilation; Vasodilator Agents | 2008 |
Non-hemodynamic effects of organic nitrates and the distinctive characteristics of pentaerithrityl tetranitrate.
Topics: Animals; Drug Administration Schedule; Drug Tolerance; Heart Diseases; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Oxidative Stress; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Vasodilator Agents | 2009 |
Long-term use of short- and long-acting nitrates in stable angina pectoris.
Topics: Angina Pectoris; Animals; Drug Tolerance; Humans; Nitrates; Nitric Oxide; Nitroglycerin; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Vasodilator Agents | 2009 |
[Organic nitrates: still interesting after all these years].
Topics: Angina Pectoris; Animals; Drug Tolerance; Free Radicals; Heart; Heart Diseases; Heart Failure; Hemodynamics; Homeostasis; Humans; Ischemic Preconditioning, Myocardial; Meta-Analysis as Topic; Myocardial Infarction; Nitrates; Nitroglycerin; Oxidative Stress; Randomized Controlled Trials as Topic; Reactive Oxygen Species; Treatment Outcome; Vasodilator Agents | 2009 |
Organic nitrates and nitrate tolerance--state of the art and future developments.
Topics: Animals; Coronary Artery Disease; Drug Tolerance; Humans; Nitrates; Nitroglycerin; Vasodilation; Vasodilator Agents | 2010 |
Nitrates for acute heart failure syndromes.
Topics: Acute Disease; Adult; Heart Failure; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Randomized Controlled Trials as Topic; Syndrome; Vasodilator Agents | 2013 |
Use of nitrates in ischemic heart disease.
Topics: Angina Pectoris; Coronary Artery Disease; Delayed-Action Preparations; Drug Tolerance; Humans; Myocardial Ischemia; Nitrates; Nitroglycerin | 2015 |
Cluster Headache: Rapid Evidence Review.
Topics: Adult; Alcohol Drinking; Cluster Headache; Female; Humans; Male; Nitrates; Nitroglycerin; Oxygen; Pain; Physical Examination; Risk Factors; Steroids; Temporal Lobe; Time Factors; Tryptamines; Vagus Nerve Stimulation; Young Adult | 2022 |
The Efficacy of Nitrates for Bone Health: A Systematic Review and Meta-Analysis of Observational and Randomized Controlled Studies.
Topics: Bone and Bones; Bone Density; Female; Fractures, Bone; Humans; Isosorbide Dinitrate; Male; Nitrates; Nitric Oxide Donors; Nitroglycerin; Risk Factors | 2022 |
Efficacy of Combined Management with Nonsteroidal Anti-inflammatory Drugs for Prevention of Pancreatitis After Endoscopic Retrograde Cholangiography: a Bayesian Network Meta-analysis.
Topics: Administration, Rectal; Anti-Inflammatory Agents, Non-Steroidal; Cholangiopancreatography, Endoscopic Retrograde; Diclofenac; Epinephrine; Humans; Indomethacin; Melatonin; Network Meta-Analysis; Nitrates; Nitroglycerin; Pancreatitis; Somatostatin; Systematic Reviews as Topic | 2022 |
The Generation of Nitric Oxide from Aldehyde Dehydrogenase-2: The Role of Dietary Nitrates and Their Implication in Cardiovascular Disease Management.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Cardiovascular Diseases; Humans; Nitrates; Nitric Oxide; Nitroglycerin; Vasodilator Agents | 2022 |
57 trial(s) available for nitrates and nitroglycerin
| Article | Year |
|---|---|
Is the use of long acting nitrates beneficial in the patient with angina pectoris? (The positive side).
Topics: Administration, Oral; Angina Pectoris; Biological Availability; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Drug Stability; Electrocardiography; Heart Failure; Heart Rate; Humans; Isosorbide Dinitrate; Kinetocardiography; Myocardial Contraction; Nitrates; Nitroglycerin; Ointments; Oxygen Consumption; Vascular Resistance | 1977 |
Is the use of long acting nitrates beneficial in the patient with angina pectoris? (The negative side).
Topics: Angina Pectoris; Animals; Clinical Trials as Topic; Coronary Circulation; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Inactivation, Metabolic; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1977 |
Acute drug testing with nitrates: angina relief during treadmill exercise.
Topics: Adult; Angina Pectoris; Drug Evaluation; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Physical Exertion | 1977 |
[Effects of prolonged-action nitrates on platelet aggregation and prostaglandin formation].
Topics: Angina Pectoris; Delayed-Action Preparations; Humans; Middle Aged; Nitrates; Nitroglycerin; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins | 1992 |
Modest doses of nitroglycerin do not interfere with beef lung heparin anticoagulation in patients taking nitrates.
Topics: Adult; Anticoagulants; Aspirin; Drug Administration Schedule; Drug Interactions; Heart Valve Diseases; Heparin; Humans; Intraoperative Care; Myocardial Revascularization; Nitrates; Nitroglycerin; Partial Thromboplastin Time; Prospective Studies; Whole Blood Coagulation Time | 1992 |
A summary index for the assessment of quality of life in angina pectoris.
Topics: Abstracting and Indexing; Administration, Cutaneous; Angina Pectoris; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Quality of Life; Reproducibility of Results; Surveys and Questionnaires; Vasodilator Agents | 1991 |
Angina: evolution of the role of nitrates.
Topics: Angina Pectoris; Exercise Test; Humans; Nitrates; Nitroglycerin; Randomized Controlled Trials as Topic | 1990 |
[An assessment of the efficacy of a course of using different forms of prolonged-action nitrates in patients with stable stenocardia with the help of repeated daily ECG monitoring].
Topics: Adult; Angina Pectoris; Circadian Rhythm; Coronary Angiography; Delayed-Action Preparations; Drug Evaluation; Electrocardiography, Ambulatory; Exercise Test; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Physical Exertion; Tablets | 1990 |
[Development and status of nitrate therapy in East Germany].
Topics: Angina Pectoris; Delayed-Action Preparations; Dose-Response Relationship, Drug; Germany, East; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Propylene Glycols; Vasodilator Agents | 1989 |
[Dose-response relationship of nitrate therapy of angina pectoris].
Topics: Administration, Cutaneous; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1986 |
[Monotherapy of patients with stenocardia with individually administered doses of delayed-action nitrates (Working Group for Cooperative Studies on Anti-anginal Drugs)].
Topics: Administration, Buccal; Administration, Cutaneous; Administration, Oral; Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Ointments; Tablets; Time Factors | 1988 |
Tolerance to the hemodynamic and antianginal effects of the organic nitrates.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin | 1985 |
Prophylactic therapy of angina pectoris with organic nitrates: relationship of drug efficacy and clinical experimental design.
Topics: Angina Pectoris; Clinical Trials as Topic; Erythrityl Tetranitrate; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Placebos; Research Design; Time Factors | 1973 |
Effects of alprenolol and isosorbide dinitrate in angina pectoris. A comparative study with methodological considerations.
Topics: Activities of Daily Living; Adult; Aged; Alprenolol; Angina Pectoris; Electrocardiography; Female; Furans; Heart Function Tests; Humans; Isosorbide Dinitrate; Male; Methods; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Physical Exertion; Placebos; Vasodilator Agents | 1973 |
Action and nomenclature of nitroglycerin and nitrate esters.
Topics: Administration, Oral; Angina Pectoris; Clinical Trials as Topic; Coronary Vessels; Humans; Nitrates; Nitroglycerin; Terminology as Topic; Vasodilator Agents | 1972 |
The long-acting hemodynamic effects of isosorbide dinitrate.
Topics: Angina Pectoris; Blood Pressure; Cardiac Output; Cardiac Volume; Exercise Test; Furans; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Placebos; Time Factors; Vascular Resistance; Vasodilator Agents | 1972 |
Hemodynamic response of oral long-acting nitrates: evidence of gastrointestinal absorption.
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Blood Flow Velocity; Clinical Trials as Topic; Coronary Disease; Delayed-Action Preparations; Female; Fingers; Furans; Humans; Intestinal Absorption; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Placebos; Plethysmography; Pulse; Tablets; Vasodilator Agents | 1972 |
Stress tests and the evaluation of anti-anginal drugs.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Erythrityl Tetranitrate; Evaluation Studies as Topic; Exercise Test; Heart; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate | 1967 |
Propranolol combined with isosorbide dinitrate versus placebo in angina pectoris.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Drug Synergism; Electrocardiography; Exercise Test; Furans; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Physical Exertion; Placebos; Propranolol | 1969 |
Rapidity of the hypotensive effect of short-acting nitrous compounds.
Topics: Adolescent; Adult; Aerosols; Amyl Nitrite; Angina Pectoris; Blood Pressure; Depression, Chemical; Female; Heart Rate; Humans; Male; Middle Aged; Nitrates; Nitrites; Nitroglycerin; Tablets; Time Factors | 1969 |
Sublingual isosorbide dinitrate therapy versus sublingual acebo in angina pectoris.
Topics: Administration, Oral; Adult; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Furans; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Physical Exertion; Placebos | 1970 |
Evaluation of nitroglycerin in angina in patients on isosorbide dinitrate.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Furans; Heart; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Placebos | 1970 |
Therapy of angina pectoris with propranolol and long-acting nitrates.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Exercise Test; Female; Furans; Heart Rate; Humans; Ischemia; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Placebos; Propranolol; Valsalva Maneuver; Vasodilator Agents | 1969 |
Therapy of angina pectoris with propranolol and long-acting nitrates.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Exercise Test; Female; Furans; Heart Function Tests; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Placebos; Propranolol | 1969 |
The effects of chewable isosorbide dinitrate in coronary insufficiency. A report on exercise electrocardiograms in 13 patients.
Topics: Administration, Oral; Aged; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Electrocardiography; Exercise Test; Female; Furans; Heart; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Placebos | 1971 |
Clinical and circulatory effects of isosorbide dinitrate. Comparison with nitroglycerin.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Drug Synergism; Electrocardiography; Furans; Heart; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Middle Aged; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Physical Exertion; Placebos; Time Factors | 1971 |
The 'overlap' method of comparing drugs.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Female; Humans; Male; Methods; Middle Aged; Nitrates; Nitroglycerin; Prenylamine | 1971 |
Metabolism of nitroglycerin in man: influence of phenobarbital.
Topics: Clinical Trials as Topic; Enzyme Induction; Headache; Humans; Male; Nausea; Nitrates; Nitroglycerin; Phenobarbital | 1971 |
Quantitative angiography: the measurement of coronary vasomobility in the intact animal and man.
Topics: Administration, Oral; Adult; Angina Pectoris; Angiocardiography; Animals; Cineangiography; Clinical Trials as Topic; Coronary Disease; Coronary Vessels; Dogs; Elasticity; Female; Furans; Humans; Isosorbide Dinitrate; Male; Methods; Middle Aged; Nitrates; Nitroglycerin; Placebos; Sorbitol; Vasodilator Agents | 1971 |
Role of nitroglycerin in effort angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Nitrates; Nitroglycerin; Time Factors | 1983 |
[Nitrate tolerance: pro and con].
Topics: Angina Pectoris; Cardiac Output; Clinical Trials as Topic; Drug Administration Schedule; Drug Tolerance; Headache; Heart Rate; Humans; Hypertension; Isosorbide Dinitrate; Long-Term Care; Nitrates; Nitroglycerin | 1984 |
[Peripheral vasodilator agents in cardiology].
Topics: Clinical Trials as Topic; Coronary Vessels; Heart Failure; Hemodynamics; Humans; Hydralazine; Myocardial Infarction; Nitrates; Nitroglycerin; Nitroprusside; Phentolamine; Piperazines; Prazosin; Quinazolines; Vasodilator Agents | 1980 |
Short and long-acting oral nitrates for stable angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Delayed-Action Preparations; Drug Therapy, Combination; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; United States; United States Food and Drug Administration; Vasodilator Agents | 1994 |
[Hemodynamics effects of continuous infusion of molsidomine and nitrates and subsequent oral medication in therapy of acute myocardial infarct].
Topics: Administration, Oral; Aged; Aged, 80 and over; Female; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Molsidomine; Myocardial Infarction; Nitrates; Nitroglycerin; Vasodilator Agents | 1994 |
Investigation of therapeutic mechanisms of atenolol and diltiazem in patients with variable-threshold angina.
Topics: Aged; Angina Pectoris, Variant; Atenolol; Blood Pressure; Coronary Angiography; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Nitrates; Nitroglycerin; Oxygen Consumption | 1994 |
Long-term nitrate treatment increases cardiac events in patients with healed myocardial infarction. Secondary Prevention Group.
Topics: Aged; Death, Sudden, Cardiac; Double-Blind Method; Drug Tolerance; Female; Heart Failure; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Odds Ratio; Recurrence; Time Factors; Vasodilator Agents | 1996 |
[Randomized, double-blind, placebo-controlled study of supplemental vitamin E on attenuation of the development of nitrate tolerance].
Topics: Aged; Antioxidants; Double-Blind Method; Drug Interactions; Drug Tolerance; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Nitrates; Nitroglycerin; Vasodilator Agents; Vitamin E | 1998 |
Preventive effects of angiotensin-converting enzyme inhibitors on nitrate tolerance during continuous transdermal application of nitroglycerin in patients with chronic heart failure.
Topics: Administration, Cutaneous; Aged; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Platelets; Blood Pressure; Body Weight; Chronic Disease; Cyclic GMP; Drug Tolerance; Female; Forearm; Heart Failure; Heart Rate; Hematocrit; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Norepinephrine; Regional Blood Flow; Renin; Systole; Vasodilator Agents | 1998 |
Diurnal variation of flow-mediated vasodilation in healthy premenopausal women.
Topics: Adult; Blood Pressure; Brachial Artery; Catecholamines; Circadian Rhythm; Cyclic GMP; Endothelium, Vascular; Female; Heart Rate; Humans; Hydrocortisone; Lipids; Nitrates; Nitric Oxide; Nitroglycerin; Premenopause; Reference Values; Vasodilation; Vasodilator Agents | 2000 |
Evaluation of endothelium-dependent vasodilation in the human peripheral circulation.
Topics: Adult; Aged; Brachial Artery; Endothelium, Vascular; Female; Forearm; Humans; Hyperemia; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Nitroprusside; Regional Blood Flow; Ultrasonography; Vasodilation; Vasodilator Agents | 2000 |
Estrogen replacement therapy in postmenopausal women augments reactive hyperemia in the forearm by reducing angiotensin converting enzyme activity.
Topics: Blood Flow Velocity; Endothelium, Vascular; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Forearm; Humans; Hyperemia; Lipids; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Peptidyl-Dipeptidase A; Plethysmography; Postmenopause; Vasodilation; Vasodilator Agents | 2001 |
Platelet nitric oxide and superoxide release during the development of nitrate tolerance: effect of supplemental ascorbate.
Topics: Adult; Antioxidants; Ascorbic Acid; Blood Platelets; Cross-Over Studies; Cyclic GMP; Double-Blind Method; Drug Tolerance; Free Radicals; Hemodynamics; Humans; Male; Middle Aged; NAD; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroglycerin; Superoxides; Time Factors; Vasodilator Agents | 2002 |
Oral L-arginine does not improve endothelial dysfunction in children with chronic renal failure.
Topics: Administration, Oral; Adolescent; Arginine; Arteriosclerosis; Child; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Female; Humans; Kidney Failure, Chronic; Male; Nitrates; Nitroglycerin; Oxidative Stress; Regional Blood Flow; Stress, Mechanical; Treatment Failure; Triglycerides; Vasodilation; Vasodilator Agents | 2002 |
Impairment of vascular responses to reactive hyperemia and nitric oxide in chronic renal failure.
Topics: Blood Pressure; Creatinine; Cysteine; Endothelium, Vascular; Female; Glutathione; Homocysteine; Humans; Hyperemia; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitroglycerin; Regional Blood Flow; Vasodilation; Vasodilator Agents | 2002 |
Effect of folic acid on nitrate tolerance in healthy volunteers: differences between arterial and venous circulation.
Topics: Adult; Analysis of Variance; Arteries; Blood Pressure; Double-Blind Method; Drug Tolerance; Folic Acid; Forearm; Heart Rate; Humans; Male; Nitrates; Nitroglycerin; Veins | 2003 |
Attenuation of nitrate tolerance and oxidative stress by an angiotensin II receptor blocker in patients with coronary spastic angina.
Topics: Administration, Cutaneous; Aged; Angina Pectoris; Angiotensin Receptor Antagonists; Benzimidazoles; Biomarkers; Biphenyl Compounds; Brachial Artery; Coronary Vasospasm; Dose-Response Relationship, Drug; Drug Tolerance; Female; Headache; Hemodynamics; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Oxidative Stress; Receptor, Angiotensin, Type 1; Tetrazoles; Thioredoxins; Treatment Outcome; Ultrasonography; Vascular Patency | 2003 |
Effect of transdermal nitroglycerin on inflammatory mediators in patients with peripheral atherosclerotic vascular disease.
Topics: Administration, Cutaneous; Adult; Aged; Anti-Inflammatory Agents; Arteriosclerosis; Biomarkers; C-Reactive Protein; Cyclic GMP; Double-Blind Method; E-Selectin; Female; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Middle Aged; Nitrates; Nitrites; Nitroglycerin; Peripheral Vascular Diseases; Pilot Projects; Statistics, Nonparametric; Vascular Cell Adhesion Molecule-1; Vasculitis; Vasodilator Agents | 2003 |
[Nitrates in therapy of effort angina in hypotensive patients].
Topics: Angina Pectoris; Cross-Over Studies; Exercise Test; Humans; Hypotension; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Nitrates; Nitric Oxide Donors; Nitroglycerin; Placebos; Time Factors; Vasodilator Agents | 2003 |
Different effect of hormone replacement therapy, DHEAS and tibolone on endothelial function in postmenopausal women with increased cardiovascular risk.
Topics: Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Dehydroepiandrosterone; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Forearm; Humans; Medroxyprogesterone; Middle Aged; Nitrates; Nitrites; Nitroglycerin; Norpregnenes; Postmenopause; Pulsatile Flow; Regional Blood Flow; Treatment Outcome; Vasodilation | 2005 |
Daily consumption for six weeks of a lignan complex isolated from flaxseed does not affect endothelial function in healthy postmenopausal women.
Topics: 4-Butyrolactone; Aged; Arginine; Blood Pressure; Body Weight; Cross-Over Studies; Diet; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Female; Flax; Humans; Lignans; Middle Aged; Nitrates; Nitrites; Nitroglycerin; Patient Compliance; Placebos; Postmenopause; Vasodilation | 2006 |
Comparison of effect between nitrates and calcium channel antagonist on vascular function in patients with normal or mildly diseased coronary arteries.
Topics: Acetylcholine; Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Female; Humans; Laser-Doppler Flowmetry; Male; Middle Aged; Nitrates; Nitroglycerin; Papaverine; Severity of Illness Index; Stress, Mechanical; Treatment Outcome; Vasoconstriction; Vasodilation; Vasodilator Agents | 2008 |
Impaired arterial baroreflex function before nitrate-induced vasovagal syncope during head-up tilt test.
Topics: Adult; Baroreflex; Blood Pressure; Female; Humans; Male; Nitrates; Nitroglycerin; Syncope, Vasovagal; Tilt-Table Test | 2008 |
Oxidative stress and enhanced sympathetic vasoconstriction in contracting muscles of nitrate-tolerant rats and humans.
Topics: Adult; Animals; Biomarkers; F2-Isoprostanes; Humans; Male; Models, Animal; Muscle Contraction; Muscle, Skeletal; Nitrates; Nitroglycerin; Oxidative Stress; Oxygen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Regional Blood Flow; Sympathetic Nervous System; Vasoconstriction; Vasodilator Agents | 2012 |
Nitrates and bone turnover (NABT) - trial to select the best nitrate preparation: study protocol for a randomized controlled trial.
Topics: Administration, Cutaneous; Administration, Sublingual; Age Factors; Biomarkers; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Chemistry, Pharmaceutical; Clinical Protocols; Female; Headache; Humans; Isosorbide Dinitrate; Middle Aged; Nitrates; Nitroglycerin; Ointments; Ontario; Postmenopause; Research Design; Tablets; Time Factors; Transdermal Patch; Treatment Outcome | 2013 |
Augmentation pressure is influenced by ventricular contractility/relaxation dynamics: novel mechanism of reduction of pulse pressure by nitrates.
Topics: Adult; Aged; Arterial Pressure; Blood Pressure; Cardiac Catheterization; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Male; Middle Aged; Muscle Relaxation; Myocardial Contraction; Nitrates; Nitroglycerin; Pulse Wave Analysis; Regional Blood Flow; Stroke Volume; Ventricular Function | 2014 |
Arterial Glyceryl Trinitrate in Acute Ischemic Stroke after Thrombectomy for Neuroprotection (AGAIN): Rationale, design and protocol for a prospective randomized controlled trial.
Topics: Brain Ischemia; Humans; Ischemic Stroke; Neuroprotection; Nitrates; Nitric Oxide; Nitroglycerin; Pilot Projects; Prospective Studies; Randomized Controlled Trials as Topic; Saline Solution; Stroke; Thrombectomy; Treatment Outcome | 2022 |
Efficacy of Continuous Transdermal Nitroglycerin for Treating Hot Flashes by Inducing Nitrate Cross-tolerance in Perimenopausal and Postmenopausal Women: A Randomized Clinical Trial.
Topics: Double-Blind Method; Female; Hot Flashes; Humans; Menopause; Nitrates; Nitroglycerin; Perimenopause; Postmenopause; Treatment Outcome | 2023 |
384 other study(ies) available for nitrates and nitroglycerin
| Article | Year |
|---|---|
[Therapy of coronary heart disease].
Topics: Adrenergic beta-Antagonists; Cholesterol; Coronary Disease; Humans; Nitrates; Nitroglycerin; Strophanthins; Triglycerides | 1976 |
[Problems of combined therapy with cardiac glycosides and anti-anginal drugs (author's transl)].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Cardiac Glycosides; Coronary Disease; Drug Therapy, Combination; Hemodynamics; Humans; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Vasodilator Agents | 1977 |
Hemodynamic factors and indirect assessment of myocardial oxygen consumption in the therapy of angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Coronary Artery Bypass; Coronary Circulation; Heart Rate; Hemodynamics; Humans; Male; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Physical Education and Training | 1977 |
Effects of anti-anginal agents on cyclical reductions of coronary blood flow.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Blood Pressure; Coronary Circulation; Diltiazem; Dipyridamole; Dogs; Electrocardiography; Injections, Intravenous; Niacinamide; Nicotinic Acids; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Periodicity; Phentolamine; Propranolol; Vasodilator Agents; Verapamil | 1978 |
Unstable angina: comparison of medical and surgical management.
Topics: Angina Pectoris; Clinical Enzyme Tests; Coronary Angiography; Coronary Artery Bypass; Electrocardiography; Exercise Test; Follow-Up Studies; Humans; Meperidine; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Oxygen Inhalation Therapy; Palliative Care; Patient Readmission; Postoperative Complications; Propranolol; Risk | 1977 |
[New nitrate indications].
Topics: Dihydralazine; Drug Combinations; Heart Diseases; Humans; Hydralazine; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitroglycerin; Nitroprusside; Phentolamine; Vasodilator Agents | 1978 |
[2. International Symposium on Nitrates; Berlin 1-3 June 1978. Nitrate-effect on the heart and circulation].
Topics: Angina Pectoris; Animals; Blood Circulation; Coronary Disease; Heart; Heart Failure; Humans; Isosorbide Dinitrate; Male; Myocardial Infarction; Nitrates; Nitroglycerin; Nitroprusside; Rats | 1978 |
[Peroral nitrate therapy in severe cardiac insufficiency following acute myocardial infarct].
Topics: Administration, Oral; Aged; Delayed-Action Preparations; Heart Failure; Humans; Isosorbide Dinitrate; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin | 1978 |
[Response of the arteriolar circulation evaluated by means of photoplethysmography after nitroderivatives].
Topics: Arterial Occlusive Diseases; Arteries; Arterioles; Blood Circulation; Erythrityl Tetranitrate; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Plethysmography | 1977 |
[Vasodilator therapy of heart failure].
Topics: Heart Failure; Humans; Hydralazine; Nitrates; Nitroglycerin; Nitroprusside; Prazosin; Stroke Volume; Vascular Resistance; Vasodilator Agents | 1979 |
Clinical use of nitrates. II. Nitrates in congestive heart failure.
Topics: Administration, Oral; Drug Evaluation; Heart Failure; Humans; Nitrates; Nitroglycerin; Ointments; Substance-Related Disorders | 1979 |
Nonparenteral vasodilator therapy for chronic congestive heart failure.
Topics: Heart Failure; Hemodynamics; Humans; Hydralazine; Nitrates; Nitroglycerin; Prazosin; Vasodilator Agents | 1979 |
Changing concepts in the management of congestive cardiac failure and acute myocardial infarction.
Topics: Heart Failure; Hospitalization; Humans; Length of Stay; Myocardial Infarction; Nitrates; Nitroglycerin | 1979 |
Effect of 2-nicotinamidethyl nitrate (SG 75) on coronary circulation.
Topics: Animals; Constriction, Pathologic; Coronary Circulation; Coronary Vessels; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Ligation; Niacinamide; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Vasodilator Agents; Verapamil | 1978 |
Effects of 2-nicotinamidoethyl nitrate (SG-75) on dog coronary artery and cat papillary muscle.
Topics: Animals; Calcium Chloride; Cats; Coronary Vessels; Dogs; Electric Stimulation; Female; Isoproterenol; Male; Muscle Contraction; Niacinamide; Nitrates; Nitroglycerin; Papillary Muscles | 1979 |
Effects of 2-nicotinamidoethyl nitrate on the cardiovascular system.
Topics: Animals; Blood Pressure; Cardiovascular System; Cerebrovascular Circulation; Coronary Circulation; Coronary Vessels; Dogs; Energy Metabolism; Female; Heart; Heart Rate; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardium; Niacinamide; Nitrates; Nitroglycerin; Vasodilator Agents; Veins | 1979 |
Medical management of angina pectoris.
Topics: Angina Pectoris; Diet; Dose-Response Relationship, Drug; Humans; Nitrates; Nitroglycerin; Propranolol; Triglycerides | 1977 |
Drug management of stable angina pectoris.
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Physical Exertion; Propranolol; Vasodilator Agents | 1977 |
Afterload reduction in congestive heart failure.
Topics: Dopamine; Heart Failure; Humans; Hydralazine; Nitrates; Nitroglycerin; Nitroprusside; Phentolamine; Prazosin; Vasodilator Agents | 1978 |
Usefulness of long-acting nitrates in cardiovascular disease.
Topics: Cardiovascular Diseases; Coronary Disease; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Time Factors; Vasodilator Agents | 1978 |
[Nitrates and other peripheral vasodilator agents in acute myocardial infarct and congestive heart failure].
Topics: Acute Disease; Heart Failure; Hemodynamics; Humans; Myocardial Infarction; Nitrates; Nitroglycerin; Vasodilator Agents | 1978 |
Comparative vasodilator effects of nitroglycerin, pentaerythritol trinitrate and biometabolites, and other organic nitrates.
Topics: Animals; Coronary Vessels; Dogs; Drug Interactions; Female; Hemodynamics; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin; Propylene Glycols; Regional Blood Flow; Tachyphylaxis; Vasodilator Agents | 1975 |
Unstable coronary artery disease: comparison of medical and surgical treatment.
Topics: Adult; Aged; Angina Pectoris; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Delayed-Action Preparations; Diuretics; Female; Follow-Up Studies; Heart Ventricles; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Propranolol; Prospective Studies | 1975 |
Dynamite poisoning in Hereford crossbreds in southeastern Ontario.
Topics: Animals; Cattle; Cattle Diseases; Female; Nitrates; Nitroglycerin; Ontario | 1975 |
The gastrointestinal absorption of organic nitrates.
Topics: Administration, Oral; Animals; Delayed-Action Preparations; Dogs; Humans; Intestinal Absorption; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Rabbits; Rats; Tablets | 1975 |
[Proceedings: The effect of nitrates on the systemic circulation and the myocardial oxygen consumption].
Topics: Blood Circulation; Coronary Disease; Coronary Vessels; Humans; Isosorbide Dinitrate; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Regional Blood Flow | 1975 |
Nitroglycerin revisited: chemistry, biochemistry, interactions.
Topics: Alcohols; Animals; Biotransformation; Carbon Dioxide; Chemical Phenomena; Chemistry; Drug Interactions; Drug Synergism; Drug Tolerance; Half-Life; Humans; In Vitro Techniques; Narcotics; Nitrates; Nitroglycerin; Oxidoreductases; Phenobarbital; Protein Binding | 1975 |
The collection and determination of ethylene glycol dinitrate, nitroglycerine, and trinitrotulene explosive vapors.
Topics: Chromatography, Thin Layer; Ethylene Glycols; Explosions; Forensic Medicine; Nitrates; Nitroglycerin; Trinitrotoluene; Volatilization | 1976 |
Long-acting nitrates in the treatment of angina pectoris.
Topics: Angina Pectoris; Delayed-Action Preparations; Erythrityl Tetranitrate; Hemodynamics; Humans; Isosorbide Dinitrate; Methods; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Physical Exertion; Substance-Related Disorders | 1976 |
[Influence of nitrates on regional myocardial blood flow and left ventricular wall motion].
Topics: Coronary Circulation; Coronary Disease; Diagnosis, Computer-Assisted; Heart Ventricles; Humans; Isosorbide Dinitrate; Myocardial Contraction; Nitrates; Nitroglycerin; Regional Blood Flow; Vascular Resistance; Xenon Radioisotopes | 1976 |
Central noradrenergic activity and the cardiovascular effects of nitroglycerin and amyl nitrate.
Topics: Animals; Blood Pressure; Cisterna Magna; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Methoxyhydroxyphenylglycol; Nitrates; Nitroglycerin; Nitroprusside; Pentanols; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Yohimbine | 1992 |
Total prevention of the development of in vitro tolerance to organic nitrates. Experiments with antioxidants.
Topics: Animals; Antioxidants; Aorta, Thoracic; Drug Tolerance; Female; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Muscle Relaxation; Nitrates; Nitroglycerin; Parasympatholytics; Rabbits; Vasodilator Agents | 1992 |
Thiol-mediated generation of nitric oxide accounts for the vasodilator action of furoxans.
Topics: Animals; Coronary Circulation; Female; Guanylate Cyclase; Guinea Pigs; Male; Mercaptoethanol; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Nitroso Compounds; Oxadiazoles; Prodrugs; S-Nitrosothiols; Sulfhydryl Compounds; Vasodilator Agents | 1992 |
Inhibition of nitrovasodilator- and acetylcholine-induced relaxation and cyclic GMP accumulation by the cytochrome P-450 substrate, 7-ethoxyresorufin.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Aorta; Biotransformation; Cyclic GMP; Cytochrome P-450 Enzyme System; Drug Interactions; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxazines; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1992 |
Improved gas chromatographic assay for the simultaneous determination of nitroglycerin and its mono- and dinitrate metabolites.
Topics: Chromatography, Gas; Humans; Male; Nitrates; Nitroglycerin | 1992 |
[Therapy with nitrates in the post-infarct phase].
Topics: Hemodynamics; Humans; Myocardial Infarction; Nitrates; Nitroglycerin; Survival Rate | 1992 |
Nitrates.
Topics: Cardiovascular Diseases; Coronary Disease; Drug Interactions; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Patient Education as Topic | 1992 |
Comparison of nicorandil-induced relaxation, elevations of cyclic guanosine monophosphate and stimulation of guanylate cyclase with organic nitrate esters.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Activation; Esters; Female; Guanylate Cyclase; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Nitric Oxide; Nitroglycerin; Stimulation, Chemical; Vasodilator Agents | 1991 |
Vascular nitric oxide-generating activities for organic nitrites and organic nitrates are distinct.
Topics: Amyl Nitrite; Animals; Cattle; Coronary Vessels; Cysteine; Cytosol; Hot Temperature; In Vitro Techniques; Kinetics; Microsomes; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Rats; Subcellular Fractions | 1991 |
Molecular mechanisms of nitrovasodilator bioactivation.
Topics: Amyl Nitrite; Enzyme Activation; Guanylate Cyclase; Isosorbide Dinitrate; Methemoglobin; Molsidomine; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxyhemoglobins | 1991 |
Nitrate tolerance induced by nicorandil or nitroglycerin is associated with minimal loss of nicorandil vasodilator activity.
Topics: Animals; Arteries; Cattle; Coronary Vessels; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Nitric Oxide; Nitroglycerin; Vasodilator Agents | 1990 |
Reduced nitric oxide release causes nitrate tolerance in the intact coronary circulation.
Topics: Animals; Bradykinin; Cell Line; Coronary Vessels; Cyclic GMP; Drug Tolerance; Fibroblasts; Heart; Iloprost; Lung; Molsidomine; Myocardium; Nitrates; Nitric Oxide; Nitroglycerin; Rabbits; Rats; Vasodilator Agents | 1991 |
Systolic intra-cavitary gradients following aortic valve replacement: an echo-Doppler study.
Topics: Adult; Aged; Aged, 80 and over; Aortic Valve; Aortic Valve Stenosis; Blood Flow Velocity; Echocardiography; Echocardiography, Doppler; Female; Heart Valve Prosthesis; Heart Ventricles; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Pentanols; Pressure; Stroke Volume; Systole; Ventricular Function, Left | 1991 |
Cardiovascular profile of 5 novel nitrate-esters: a comparative study with nitroglycerin in pigs with and without left ventricular dysfunction.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiac Output, Low; Coronary Circulation; Coronary Disease; Female; Heart Diseases; Hemodynamics; Male; Microspheres; Myocardial Contraction; Nitrates; Nitroglycerin; Regional Blood Flow; Swine; Ventricular Function, Left | 1991 |
Hirudin and nitrates inhibit the thrombin-induced release of endothelin from the intact porcine aorta.
Topics: Animals; Aorta; Calcimycin; Endothelins; Hirudins; In Vitro Techniques; Methylene Blue; Nitrates; Nitroglycerin; Swine; Thrombin | 1991 |
Comparison of isobutyl nitrate and isobutyl nitrite: tolerance and cross-tolerance to glyceryl trinitrate.
Topics: Animals; Aorta, Thoracic; Butanes; Dose-Response Relationship, Drug; Drug Tolerance; Female; In Vitro Techniques; Isometric Contraction; Muscle, Smooth, Vascular; Nitrates; Nitrites; Nitroglycerin; Phenylephrine; Rabbits | 1991 |
[New-onset angina pectoris: clinical aspects, diagnosis, prognosis and treatment tactics].
Topics: Angina Pectoris; Aspirin; Calcium Channel Blockers; Electrocardiography; Exercise Test; Humans; Middle Aged; Nitrates; Nitroglycerin; Prognosis | 1991 |
Mechanisms of nitrate-induced vasodilatation and tolerance.
Topics: Animals; Cattle; Coronary Vessels; Cysteine; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Vasodilation | 1990 |
Effects of various nitrates on pulmonary wedge pressure in acute myocardial infarction.
Topics: Administration, Cutaneous; Administration, Oral; Administration, Sublingual; Humans; Myocardial Infarction; Nitrates; Nitroglycerin; Pulmonary Wedge Pressure; Vasodilator Agents | 1990 |
Cytochrome P-450 mediated biotransformation of organic nitrates.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chromatography, Gas; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; In Vitro Techniques; Isosorbide Dinitrate; Kinetics; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitroglycerin; Oxygen; Phenobarbital; Rats; Rats, Inbred Strains; Stereoisomerism | 1990 |
Introductory remarks about clinically relevant pharmacokinetic properties of organic nitrates.
Topics: Administration, Cutaneous; Coronary Disease; Humans; Infusions, Intravenous; Nitrates; Nitroglycerin | 1990 |
Determinants of in vitro nitroglycerin tolerance induction and reversal: influence of dose regimen, nitrate-free period, and sulfhydryl supplementation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcysteine; Animals; Cattle; Drug Tolerance; In Vitro Techniques; Muscle Relaxation; Nitrates; Nitroglycerin; Prostaglandin Endoperoxides, Synthetic; Sulfhydryl Compounds | 1989 |
Effectiveness of interval nitrate therapy in angina pectoris.
Topics: Administration, Cutaneous; Angina Pectoris; Drug Administration Schedule; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1989 |
[Ambulatory treatment of chronic cardiac insufficiency with prolonged administration of nitrates].
Topics: Administration, Oral; Cardiac Glycosides; Coronary Disease; Diuretics; Drug Evaluation; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Time Factors | 1989 |
[Evaluation of the antianginal efficacy of sustonit compared with other nitrate drug forms].
Topics: Adult; Angina Pectoris; Coronary Disease; Delayed-Action Preparations; Drug Evaluation; Exercise Test; Humans; Middle Aged; Nitrates; Nitroglycerin; Physical Exertion; Tablets | 1989 |
[The efficacy of prolonged-action nitrates in stenocardia].
Topics: Adult; Angina Pectoris; Delayed-Action Preparations; Drug Evaluation; Female; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Physical Endurance; Tablets | 1989 |
[Nitroglycerin test in the nitrong treatment of patients with ischemic heart disease and chronic obstructive bronchitis].
Topics: Bronchitis; Chronic Disease; Coronary Disease; Hemodynamics; Humans; Monitoring, Physiologic; Nitrates; Nitroglycerin; Respiration | 1989 |
Nitrate tolerance and its consequences for the clinician.
Topics: Angina Pectoris; Animals; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1989 |
[Therapeutic tolerance with derivative nitrates].
Topics: Angina Pectoris; Animals; Drug Tolerance; Heart Failure; Humans; Nitrates; Nitroglycerin | 1989 |
Effect of pertussis toxin and the cGMP lowering agent LY83583 on the relaxation induced by nitrates in isolated bovine mesenteric artery. A comparison between glyceryl trinitrate, isosorbide dinitrate and isosorbide 5-mononitrate.
Topics: Aminoquinolines; Animals; Cattle; Cyclic GMP; Isosorbide Dinitrate; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Pertussis Toxin; Vascular Resistance; Virulence Factors, Bordetella | 1989 |
[Drugs in secondary prevention of ischemic heart disease: achievements, problems and prospects].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Nadolol; Nifedipine; Nitrates; Nitroglycerin; Propranolol; Verapamil | 1989 |
Effects of atrial natriuretic polypeptide and organic nitrates on levels of relaxation and cyclic nucleotide of canine coronary artery with and without endothelial injury.
Topics: Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilation | 1988 |
Evidence for a correlation between nitric oxide formation by cleavage of organic nitrates and activation of guanylate cyclase.
Topics: Animals; Enzyme Activation; Guanylate Cyclase; Nitrates; Nitric Oxide; Nitroglycerin; Rats; Sulfhydryl Compounds | 1985 |
[Results of the conservative treatment of patients with unstable stenocardia].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Drug Therapy, Combination; Follow-Up Studies; Hospitalization; Humans; Infusions, Parenteral; Male; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin | 1986 |
Use of drugs in cardiac rehabilitation.
Topics: Adrenergic beta-Antagonists; Amiodarone; Diltiazem; Drug Therapy, Combination; Electrocardiography; Exercise Test; Heart Diseases; Humans; Middle Aged; Nifedipine; Nitrates; Nitroglycerin; Physical Exertion; Verapamil | 1986 |
Mode of action of nitrates with regard to vasodilatation and tolerance.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Nitrates; Nitroglycerin; Vasodilation | 1986 |
Mechanism of vasodilation by nitrates: role of cyclic GMP.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Nitrates; Nitroglycerin; Vasodilator Agents | 1987 |
The use of beta-adrenergic blocking agents, i.v. nitrates and calcium channel blocking agents following acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Humans; Infusions, Intravenous; Metoprolol; Myocardial Infarction; Nifedipine; Nitrates; Nitroglycerin; Nitroprusside; Verapamil | 1988 |
Nitrates do not affect prostacyclin formation by rat arteries: this is unrelated to increased vascular prostacyclin formation with age.
Topics: 6-Ketoprostaglandin F1 alpha; Aging; Animals; Arteries; Epoprostenol; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Rats; Rats, Inbred Strains | 1987 |
Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation, and guanylate cyclase activation by glyceryl trinitrate and the enantiomers of isoidide dinitrate.
Topics: Animals; Aorta; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Guanylate Cyclase; Male; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Rats; Rats, Inbred Strains; Stereoisomerism; Sugar Alcohols; Vasodilation | 1988 |
Guanylate cyclase activation by organic nitrates is not mediated via nitrite.
Topics: Enzyme Activation; Guanylate Cyclase; Isosorbide Dinitrate; Kinetics; Niacinamide; Nicorandil; Nitrates; Nitrites; Nitroglycerin; Sulfhydryl Compounds; Vasodilator Agents | 1988 |
Desensitization of guanylate cyclase in nitrate tolerance does not impair endothelium-dependent responses.
Topics: Animals; Aorta, Thoracic; Biological Factors; Cattle; Cells, Cultured; Cyclic GMP; Drug Tolerance; Endothelium, Vascular; Enzyme Activation; Female; Guanylate Cyclase; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Rabbits; Sulfhydryl Compounds; Vasodilation | 1988 |
[Nitrates in the combined treatment of congestive heart failure patients in a mountainous location].
Topics: Adolescent; Adult; Altitude; Digoxin; Drug Evaluation; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Kyrgyzstan; Male; Middle Aged; Nitrates; Nitroglycerin | 1986 |
The kinetic differences between sodium nitrite, amyl nitrite and nitroglycerin oxidation of hemoglobin.
Topics: Erythrocytes; Hemoglobins; Humans; Kinetics; Methemoglobin; Nitrates; Nitroglycerin; Oxidation-Reduction; Oxyhemoglobins; Pentanols | 1986 |
Pharmacological principles in the development of tolerance.
Topics: Adenylyl Cyclases; Animals; Coronary Circulation; Coronary Disease; Cyclic AMP; Drug Tolerance; Humans; Kinetics; Nitrates; Nitroglycerin; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1985 |
Mechanisms of nitrate-induced vasodilatation and tolerance on a biochemical base.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Pressure; Cattle; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Isosorbide Dinitrate; Methylene Blue; Nitrates; Nitroglycerin; Nitroprusside; Vasodilation | 1985 |
The role of transdermal nitroglycerin in the treatment of coronary heart disease.
Topics: Administration, Topical; Coronary Disease; Heart; Heart Failure; Humans; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin | 1986 |
Clinical relevance of nitrate hemodynamic attenuation.
Topics: Administration, Topical; Angina Pectoris; Coronary Disease; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Receptors, Drug; Vasodilation | 1986 |
Nitrates in the treatment of coronary artery disease.
Topics: Coronary Disease; Dosage Forms; Drug Tolerance; Humans; Nitrates; Nitroglycerin | 1986 |
Effects of nitrates in various vascular sections and regions.
Topics: Animals; Arteries; Arterioles; Blood Vessels; Dogs; Drug Tolerance; Hemodynamics; Molsidomine; Nitrates; Nitroglycerin; Vasodilation; Veins | 1986 |
Nitrosothiol and nitrate tolerance.
Topics: Animals; Aorta; Drug Tolerance; Male; Mercaptoethanol; Nitrates; Nitroglycerin; Nitroso Compounds; Penicillamine; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Vasodilation | 1986 |
Acute effects of nitrates on left ventricular performance and energetics.
Topics: Energy Metabolism; Heart; Heart Ventricles; Humans; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption | 1986 |
[Dynamic auscultation of the heart].
Topics: Diagnosis, Differential; Heart Auscultation; Heart Diseases; Heart Function Tests; Humans; Nitrates; Nitroglycerin; Pentanols; Physical Exertion; Posture; Respiration; Ventricular Function | 1987 |
[Corrective effect of nitrates and calcium antagonists on hemodynamics and ventilation in chronic bronchitis patients with a syndrome of pulmonary hypertension].
Topics: Bronchitis; Calcium Channel Blockers; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension, Pulmonary; Isosorbide Dinitrate; Nifedipine; Nitrates; Nitroglycerin; Pulmonary Heart Disease; Respiration; Vasodilator Agents; Verapamil | 1987 |
[Development of tolerance to glyceryl trinitrate and other nitrates].
Topics: Drug Tolerance; Humans; Nitrates; Nitroglycerin | 1987 |
Historical aspects of nitrate therapy.
Topics: Cardiovascular Diseases; History, 19th Century; History, 20th Century; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentanols | 1987 |
Determination of nitrates in plasma.
Topics: Biotransformation; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1987 |
Comparison of transdermal nitroglycerin therapy with previous long-acting oral or ointment nitrate therapy.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angina, Unstable; Delayed-Action Preparations; Female; Hospitalization; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Ointments; Retrospective Studies | 1987 |
Nitrate therapy in stable angina pectoris.
Topics: Angina Pectoris; Bradycardia; Humans; Hypotension; Nitrates; Nitroglycerin; Substance Withdrawal Syndrome | 1988 |
Mechanisms for the pharmacologic interaction of organic nitrates with thiols. Existence of an extracellular pathway for the reversal of nitrate vascular tolerance by N-acetylcysteine.
Topics: Acetylcysteine; Animals; Aorta; Blood Pressure; Glutathione; Humans; In Vitro Techniques; Male; Metabolic Clearance Rate; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Rats; Rats, Inbred Strains; Serine; Vasodilation | 1988 |
Stimulation of coronary vascular PGI2 by organic nitrates.
Topics: Animals; Cattle; Coronary Vessels; Epoprostenol; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Platelet Aggregation; Stereoisomerism; Structure-Activity Relationship; Sugar Alcohols; Thromboxane A2; Vasodilator Agents | 1988 |
Nitrates: the problem of tolerance.
Topics: Angina Pectoris; Drug Tolerance; Heart Failure; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1988 |
Recent advances in transdermal delivery systems.
Topics: Administration, Cutaneous; Administration, Oral; Delayed-Action Preparations; Heart Diseases; Humans; Nitrates; Nitroglycerin; Polymers | 1986 |
Nitrate tolerance--a therapeutic dilemma.
Topics: Angina Pectoris; Captopril; Coronary Disease; Drug Therapy, Combination; Drug Tolerance; Humans; Nitrates; Nitroglycerin | 1988 |
Nitrates and endothelial prostacyclin production: studies in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Blood Vessels; Cells, Cultured; Endothelium; Epoprostenol; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Thromboxane B2; Vasodilator Agents | 1985 |
[Significance of nitrates in acute therapy of heart failure with and without lung edema].
Topics: Cardiac Output, Low; Cardiomyopathy, Dilated; Dobutamine; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pulmonary Edema; Regional Blood Flow; Shock, Cardiogenic | 1985 |
Retrospective post-marketing surveillance of Transiderm-Nitro 5 in general practice in the United Kingdom.
Topics: Administration, Topical; Adult; Aged; Angina Pectoris; Calcium; Drug Therapy, Combination; Family Practice; Female; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Retrospective Studies; Time Factors | 1985 |
[Problems in long-term preventive treatment of angina pectoris using nitrates].
Topics: Administration, Topical; Angina Pectoris; Biological Availability; Delayed-Action Preparations; Drug Tolerance; Humans; Nitrates; Nitroglycerin | 1985 |
Vasodilator therapy for chronic congestive heart failure.
Topics: Captopril; Cardiac Catheterization; Heart Failure; Hospitalization; Humans; Hydralazine; Myocardial Contraction; Nitrates; Nitroglycerin; Prazosin; Pressure; Vascular Resistance; Vasodilator Agents; Veins | 1985 |
Mechanisms and therapy of silent myocardial ischemia and the effect of transdermal nitroglycerin.
Topics: Administration, Topical; Angina Pectoris; Coronary Disease; Electrocardiography; Humans; Nitrates; Nitroglycerin; Prognosis; Time Factors; Vasodilator Agents | 1985 |
Nitrate tolerance.
Topics: Administration, Topical; Angina Pectoris; Blood Pressure; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Time Factors; Vasodilator Agents | 1985 |
Pharmacology of the nitrates in angina pectoris.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Cheek; Chemical Phenomena; Chemistry; Dosage Forms; Drug Tolerance; Hemodynamics; Humans; Infusions, Parenteral; Mouth Floor; Nitrates; Nitroglycerin; Prostaglandins; Substance-Related Disorders; Vasodilator Agents | 1985 |
[Nitrates and tolerance].
Topics: Animals; Cross Reactions; Drug Tolerance; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Tachyphylaxis | 1985 |
[Nitrates in ischemic heart disease: the dependence of the effect on the route of administration and dosage of the preparation].
Topics: Administration, Oral; Coronary Disease; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Evaluation; Electrocardiography; Humans; Injections, Intravenous; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Ointments; Tablets; Time Factors | 1985 |
Drugs for angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Delayed-Action Preparations; Humans; Nitrates; Nitroglycerin; Vasodilator Agents | 1974 |
The nature of treatment selection in coronary artery disease. Experience with medical and surgical treatment of a chronic disease.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Chronic Disease; Coronary Artery Bypass; Coronary Disease; Follow-Up Studies; Humans; Nitrates; Nitroglycerin; Prognosis | 1974 |
Medical management of angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Humans; Nitrates; Nitroglycerin | 1974 |
GLC determination of nitroglycerin and isosorbide dinitrate in human plasma.
Topics: Chromatography, Gas; Furans; Humans; Isosorbide Dinitrate; Methods; Nitrates; Nitroglycerin; Time Factors; Vasodilator Agents | 1973 |
Role of inorganic nitrite in methaemoglobin formation after nitrate ester administration to the rat.
Topics: Animals; Esters; Glycols; In Vitro Techniques; Methemoglobin; Nitrates; Nitrites; Nitroglycerin; Rabbits; Rats; Spectrophotometry; Time Factors | 1973 |
Bioavailability studies of nitrates in the dog.
Topics: Administration, Oral; Animals; Biopharmaceutics; Blood Pressure; Cardiovascular System; Delayed-Action Preparations; Dogs; Dose-Response Relationship, Radiation; Heart; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Oxygen Consumption; Pentaerythritol Tetranitrate; Pulse; Vasodilator Agents | 1973 |
Unstable angina.
Topics: Angina Pectoris; Anticoagulants; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Electrocardiography; Fatigue; Heart Block; Humans; Ligation; Male; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Prognosis; Propranolol; Surgical Procedures, Operative; Tachycardia; Thoracic Arteries | 1973 |
[Therapy of angina pectoris. II. Evaluation of antianginous drugs. Nitrites and nitrates].
Topics: Amyl Nitrite; Angina Pectoris; Drug Evaluation; Humans; Isosorbide Dinitrate; Mannitol; Nitrates; Nitrites; Nitroglycerin | 1974 |
[Cases of sudden death as a consequence of long-term work with nitric esters of glycerine].
Topics: Adult; Death, Sudden; Environmental Exposure; Esters; Humans; Middle Aged; Nitrates; Nitroglycerin; Occupational Diseases; Time Factors | 1974 |
Systemic approach to the detection of explosive residues. 3. Commercial dynamite.
Topics: Chromatography, Thin Layer; Ethylene Glycols; Explosions; Forensic Medicine; Infrared Rays; Nitrates; Nitroglycerin; Oils; Solvents | 1974 |
Detection of dynamite residues on the hands of bombing suspects.
Topics: Chromatography, Thin Layer; Erythrityl Tetranitrate; Ethylenes; Explosions; Forensic Medicine; Glycols; Hand; Humans; Methods; Nitrates; Nitroglycerin; Time Factors; Ultraviolet Rays; Violence | 1972 |
Effects of ethyleneglycol dinitrate and related compounds on ethanol preference and ethanol metabolism.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Animals; Depression, Chemical; Ethanol; Ethylene Glycols; Glycols; Liver; Male; Nitrates; Nitroglycerin; Propylene Glycols; Rats; Time Factors | 1974 |
Effect of certain drugs on perfused human placenta. 8. Angiotensin-II antagonists.
Topics: Acetates; Angiotensin II; Atropine; Blood Pressure Determination; Cobalt; Cocaine; Cyproheptadine; Dibenzylchlorethamine; Dipyridamole; Ethanol; Female; Furans; Glycols; Humans; Hydralazine; In Vitro Techniques; Isosorbide Dinitrate; Muscles; Nitrates; Nitrites; Nitroglycerin; Papaverine; Perfusion; Phentolamine; Placenta; Pregnancy; Sodium; Sympatholytics; Tartrates; Tolazoline | 1968 |
Identification of the nitrate esters of five alkyl alcohols by thin-layer chromatography.
Topics: Acetone; Alcohols; Chromatography, Thin Layer; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Silicon Dioxide | 1967 |
Peripheral neuropathy in a person sensitive to dynamite.
Topics: Arteritis; Biopsy; Humans; Leg; Male; Methylprednisolone; Middle Aged; Muscles; Nitrates; Nitroglycerin; Peripheral Nervous System Diseases; Poisoning; Time Factors; Trinitrotoluene | 1969 |
Pharmacologic and biochemical evaluation of organic nitrates: attempted correlation of activities.
Topics: Animals; Chemistry, Organic; Dogs; Electron Transport; Erythrityl Tetranitrate; Evaluation Studies as Topic; Heart; In Vitro Techniques; Isosorbide Dinitrate; Mannitol; Mitochondria, Muscle; Myocardium; NAD; Nitrates; Nitroglycerin; Organic Chemistry Phenomena; Oxidative Phosphorylation; Oxidoreductases; Pentaerythritol Tetranitrate; Rats; Vasodilator Agents | 1971 |
The transformation of glyceryl trinitrate and other nitrates by glutathione-organic nitrate reductase.
Topics: Animals; Chromatography, Thin Layer; Fluorometry; Glutathione; In Vitro Techniques; Liver; NADP; Nitrates; Nitrites; Nitroglycerin; Oxidoreductases; Rats; Spectrophotometry | 1965 |
Effect of certain drugs on perfused human placenta. V. Use of alpha and beta adrenergic blocking agents to determine the specific effector site of vasoactive substances.
Topics: Adult; Diuretics; Epinephrine; Female; Humans; In Vitro Techniques; Isoproterenol; Nitrates; Nitrites; Nitroglycerin; Oxytocin; Papaverine; Phentolamine; Placenta; Sympathomimetics; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System; Vasopressins | 1965 |
[Drug therapy of angina pectoris].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Anticoagulants; Humans; Nitrates; Nitroglycerin; Oxygen Consumption; Sympatholytics | 1971 |
Nitroglycerin biotransformation by rat blood serum.
Topics: Acetamides; Animals; Azides; Biotransformation; Blood; Carbon Isotopes; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Chromatography, Thin Layer; Dialysis; Drug Stability; Glutathione; Hydrogen-Ion Concentration; Hydrolysis; Iodoacetates; Kinetics; Liver; Metabolism; NADP; Nitrates; Nitrites; Nitroglycerin; Oxalates; Oxidation-Reduction; Oxidoreductases; Rats; Silver Nitrate; Sodium; Swine; Temperature | 1970 |
Study of the increased glyceryl trinitrate metabolism after pretreatment with phenobarbital in rat liver.
Topics: Animals; Body Weight; Dactinomycin; Ethionine; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Reductase; In Vitro Techniques; Liver; Male; NADP; Nitrates; Nitroglycerin; Organ Size; Phenobarbital; Proteins; Rats; Spectrophotometry, Ultraviolet | 1972 |
The influence of the thyroid on the acute toxicity of a dynamite-sensitizing mixture.
Topics: Angina Pectoris; Animals; Epinephrine; Glycols; Hyperthyroidism; Hypothyroidism; Lethal Dose 50; Male; Nitrates; Nitroglycerin; Rats; Thiouracil; Thyroid Hormones; Thyroxine; Triiodothyronine | 1972 |
Systemic and coronary vascular effects of the 2- and the 5-mononitrate esters of isosorbide.
Topics: Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Electrocardiography; Furans; Heart Rate; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Perfusion; Pulse; Vascular Resistance | 1972 |
Gas chromatography of the nitrate esters of glycerol, isosorbide and isomannide.
Topics: Chromatography, Gas; Esters; Furans; Microchemistry; Nitrates; Nitroglycerin; Stereoisomerism | 1972 |
Organic nitrates: relationship between biotransformation and rational angina pectoris therapy.
Topics: Angina Pectoris; Animals; Biotransformation; Carbon Isotopes; Furans; Humans; Isosorbide Dinitrate; Liver; Mannitol; Nitrates; Nitroglycerin; Oxidoreductases; Rats; Vasodilator Agents | 1972 |
Clearance and metabolism of organic nitrates.
Topics: Adenosine Triphosphate; Animals; Blood; Carbon Isotopes; Erythrityl Tetranitrate; Glutathione; In Vitro Techniques; Isosorbide Dinitrate; Kinetics; Liver; Mannitol; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Rats | 1972 |
Biotransformation of nitroglycerin by organic nitrate reductase.
Topics: Animals; Biotransformation; Enzyme Activation; Glucosephosphate Dehydrogenase; Glutathione; Kinetics; Liver; Male; Nitrates; Nitroglycerin; Oxidoreductases; Phenobarbital; Proadifen; Rats | 1972 |
Medical treatment of angina pectoris. 3. Pharmacology of sublingual nitrites as antianginal drugs.
Topics: Angina Pectoris; Blood Flow Velocity; Blood Vessels; Dipyridamole; Furans; Heart; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardium; Nitrates; Nitrites; Nitroglycerin; Oxygen Consumption; Vasodilator Agents | 1972 |
Headaches in explosive magazine workers.
Topics: Air Pollution; Australia; Blood Pressure; Glycols; Headache; Humans; Male; Nitrates; Nitroglycerin; Occupational Diseases; Statistics as Topic | 1966 |
Effect of glyceryl trinitrate on extracellular fluid space of aortic strips.
Topics: Animals; Aorta; Extracellular Space; In Vitro Techniques; Indicators and Reagents; Inulin; Male; Nitrates; Nitrites; Nitroglycerin; Rabbits; Spectrophotometry | 1966 |
Blood nitrite and nitrate concentration after oral and intravenous administration of glyceryl trinitrate in rabbits.
Topics: Animals; Injections, Intravenous; Male; Nitrates; Nitrites; Nitroglycerin; Rabbits | 1966 |
Determination of traces of ethyleneglycol dinitrate (and nitroglycerine) in blood and urine.
Topics: Chromatography, Gas; Glycols; Humans; In Vitro Techniques; Nitrates; Nitroglycerin; Occupational Diseases; Skin | 1966 |
[Effect of sodium nitrate and nitroglycerine on incorporation of P-32 into energetic phosphates in the heart--antagonism to noradrenaline].
Topics: Adenosine Triphosphate; Animals; Epinephrine; Myocardium; Nitrates; Nitrites; Nitroglycerin; Norepinephrine; Phosphocreatine; Phosphorus Isotopes; Rats; Sodium | 1967 |
Characteristic pulse wave caused by organic nitrates.
Topics: Adult; Asphyxia; Blood Pressure; Electrocardiography; Ethanol; Glycols; Humans; Male; Nitrates; Nitroglycerin; Plethysmography; Pulse | 1967 |
Nitrate blood levels with controlled-release nitroglycerine.
Topics: Delayed-Action Preparations; Humans; Nitrates; Nitroglycerin | 1966 |
A preliminary study of time activity of chloroglyceryl dinitrate.
Topics: Angina Pectoris; Cardiac Output; Chlorine; Coronary Vessels; Electrocardiography; Exercise Test; Glycerol; Humans; Iodine Radioisotopes; Iodopyracet; Myocardial Infarction; Nitrates; Nitroglycerin; Regional Blood Flow; Time Factors | 1964 |
A correlation between the inhibition of monoamine oxidase activity and the relief of angina pain by organic nitrates.
Topics: Angina Pectoris; Animals; Carbon Isotopes; Erythrityl Tetranitrate; Furans; Humans; Isosorbide Dinitrate; Mannitol; Mitochondria, Muscle; Monoamine Oxidase Inhibitors; Myocardium; Nitrates; Nitroglycerin; Vasodilator Agents | 1968 |
Biological effects of nitroglycol on the metabolism of catecholamines. Clinical and experimental observations.
Topics: Adult; Amphetamine; Animals; Catecholamines; Death, Sudden; Environmental Exposure; Epinephrine; Flavoring Agents; Glycols; Humans; Injections, Intramuscular; Male; Mandelic Acids; Middle Aged; Myocardium; Nitrates; Nitrites; Nitroglycerin; Norepinephrine; Physical Exertion; Rats; Tachycardia; Tyramine; Urination | 1968 |
The absorption and biotransformation of glyceryl trinitrate-1,3-14C by rats.
Topics: Acids; Animals; Biotransformation; Carbon Dioxide; Carbon Isotopes; Chromatography, Thin Layer; Digestive System; Feces; Glycerol; Kidney; Liver; Lung; Male; Myocardium; Nitrates; Nitroglycerin; Rats; Spleen; Time Factors | 1968 |
Relationship between glutathione-dependent dentration and the vasodilator effectiveness of organic nitrates.
Topics: Animals; Dogs; Esters; Glutathione; In Vitro Techniques; Lipids; Mannitol; Muscle, Smooth; Nitrates; Nitroglycerin; Oxidoreductases; Rabbits; Solubility; Vasodilator Agents | 1969 |
[Cardiac pain and its treatment with differently acting pharmacological agents in the form of a combined preparation].
Topics: Adult; Aged; Aminophylline; Angina Pectoris; Atropine; Female; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Papaverine; Phenobarbital; Suppositories; Tablets | 1968 |
Metabolism of ethylene glycol dinitrate (ethylene dinitrate) in the rat following repeated administration.
Topics: Animals; Blood Pressure; Dogs; Drug Tolerance; Esters; Female; Glycols; In Vitro Techniques; Nitrates; Nitrites; Nitroglycerin; Rats | 1969 |
Cardiopulmonary effects of glyceryl trinitrate and isosorbide dinitrate.
Topics: Animals; Blood; Coronary Vessels; Dogs; Furans; Heart; Heart Ventricles; Hemodynamics; Injections, Intravenous; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pulmonary Circulation; Regional Blood Flow; Vasodilator Agents | 1968 |
The effect of nitrate explosives on adrenergic nerves.
Topics: Animals; Fluorescence; Glycols; Histocytochemistry; Iris; Mitochondria, Liver; Mitochondria, Muscle; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Nialamide; Nitrates; Nitroglycerin; Norepinephrine; Rats; Reserpine; Sympathetic Nervous System; Tryptamines | 1969 |
Effect of nitrates and other coronary dilators on large and small coronary vessels: an hypothesis for the mechanism of action of nitrates.
Topics: Aminophylline; Animals; Aorta; Biophysical Phenomena; Biophysics; Blood Circulation; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Coumarins; Dipyridamole; Dogs; Electricity; Glycolates; Hemodynamics; Hyperemia; Isoproterenol; Nitrates; Nitroglycerin; Papaverine; Pentaerythritol Tetranitrate; Prenylamine; Propranolol; Vasodilator Agents; Verapamil | 1969 |
A review of pharmacy for nurses.
Topics: Education, Nursing, Continuing; Nitrates; Nitrites; Nitroglycerin; Quinidine | 1969 |
Biotransformation of glyceryltrinitrate in rabbits.
Topics: Animals; Biotransformation; Chromatography; Female; Infusions, Parenteral; Injections, Intravenous; Liver; Male; Nitrates; Nitroglycerin; Phenobarbital; Portal System; Rabbits | 1969 |
Tolerance to the vascular effects of glyceryl trinitrate.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Drug Tolerance; Female; Ileum; In Vitro Techniques; Muscle, Smooth; Nitrates; Nitroglycerin; Rats; Time Factors; Uterus | 1970 |
Effect of organic nitrates on myocardial oxygen consumption in vitro.
Topics: Animals; Erythrityl Tetranitrate; Female; Heart; In Vitro Techniques; Mannitol; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Propylene Glycols; Rabbits; Stimulation, Chemical | 1970 |
The metabolic fate of nitroglycerin (trinitrin) in relation to its vascular effects.
Topics: Adipose Tissue; Administration, Oral; Animals; Blood Pressure; Blood Vessels; Dogs; Erythrocytes; Injections, Intravenous; Kidney; Liver; Lung; Muscles; Myocardium; Nitrates; Nitroglycerin; Phenobarbital; Proadifen; Rabbits | 1970 |
The use of isosorbide dinitrate in status anginosus.
Topics: Adult; Age Factors; Aged; Angina Pectoris; Electrocardiography; Female; Furans; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin | 1970 |
[Conservative therapy of angina pectoris].
Topics: Acute Disease; Amyl Nitrite; Angina Pectoris; Anticoagulants; Coronary Disease; Digitalis Glycosides; Furans; Heart Failure; Humans; Hypotension, Orthostatic; Isosorbide Dinitrate; Morphine; Myocardial Infarction; Nitrates; Nitrites; Nitroglycerin; Pentaerythritol Tetranitrate; Propranolol; Rest; Sympatholytics; Syncope; Vascular Headaches | 1970 |
Mathematical relationship of in vitro release rates and biological availability of controlled-release nitroglycerin (nitrong).
Topics: Biopharmaceutics; Blood Pressure; Delayed-Action Preparations; Humans; Kinetics; Mathematics; Models, Biological; Nitrates; Nitroglycerin; Plethysmography; Skin Temperature; Tablets; Time Factors | 1971 |
Organic nitrates: tolerance at the level of the vascular smooth muscle.
Topics: Animals; Aorta; Blood Vessels; In Vitro Techniques; Muscle, Smooth; Nitrates; Nitroglycerin; Papaverine; Proadifen; Rats | 1971 |
A ten-year reevaluation. Nitroglycerin and isosorbide dinitrate in coronary insufficiency.
Topics: Aged; Angina Pectoris; Female; Furans; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin | 1971 |
Effects of glycerol trinitrate, mannitol hexanitrate and erythritol tetranitrate on electron transport and phosphorylation in liver mitochondria.
Topics: Animals; Cattle; Electron Transport; Erythritol; Kinetics; Liver; Mannitol; Mitochondria, Liver; Nitrates; Nitroglycerin; Oxidative Phosphorylation; Oxygen Consumption; Rats; Serum Albumin, Bovine; Sugar Alcohols | 1971 |
Organic nitrate explosives as monoamino-oxidase inhibitors. Studies in vitro.
Topics: Animals; Binding, Competitive; Ethylene Glycols; In Vitro Techniques; Liver; Monoamine Oxidase Inhibitors; Nitrates; Nitroglycerin; Propylene Glycols; Rabbits | 1969 |
Pharmacologic treatment of stable anginal syndromes.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina Pectoris, Variant; Humans; Nitrates; Nitroglycerin | 1981 |
[Effectiveness of the combined use of adrenergic beta receptor blockaders and long-acting nitrates in chronic ischemic heart disease].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Chronic Disease; Coronary Disease; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Pindolol; Propanolamines; Propranolol | 1981 |
Medical management of the patient with angina pectoris: an overview of the problem.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Cardiovascular Agents; Coronary Artery Bypass; Coronary Disease; Diagnostic Errors; Humans; Nitrates; Nitroglycerin; Patient Education as Topic; Prognosis; Risk | 1982 |
[Treatment of angina pectoris with special reference to beta-blockers].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Anticoagulants; Calcium Channel Blockers; Diagnosis, Differential; Digitalis; Drug Therapy, Combination; Humans; Nifedipine; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Plants, Medicinal; Plants, Toxic; Propanolamines; Propranolol; Verapamil | 1982 |
Medical management of angina: nitrates, beta blockers, calcium channel blockers.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blockers; Coronary Vessels; Dose-Response Relationship, Drug; Drug Synergism; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Contraction; Myocardial Infarction; Nitrates; Nitroglycerin; Tablets | 1982 |
Mechanism of nitrate-induced vasodilation and tolerance.
Topics: Animals; Cattle; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Nitrates; Nitroglycerin; Vasodilation | 1983 |
Effects of 2-nicotinamidoethyl nitrate on smooth muscle cells of the guinea-pig mesenteric and portal veins.
Topics: Acetylcholine; Animals; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Membranes; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Norepinephrine; Portal Vein; Vasodilator Agents | 1982 |
Nitrate therapy in a patient with papillary dysfunction.
Topics: Ampulla of Vater; Common Bile Duct Diseases; Female; Humans; Isosorbide Dinitrate; Middle Aged; Nitrates; Nitroglycerin; Sphincter of Oddi | 1983 |
Calcium antagonists, nitrates, and new antianginal drugs.
Topics: Angina Pectoris; Calcium Channel Blockers; Humans; Hypertension; Isosorbide Dinitrate; Lidoflazine; Nifedipine; Nitrates; Nitroglycerin; Perhexiline; Prenylamine; Tachycardia; Verapamil | 1983 |
Pharmacokinetics of nitroglycerin and long-acting nitrate esters.
Topics: Absorption; Dose-Response Relationship, Drug; Humans; Isosorbide Dinitrate; Kinetics; Nitrates; Nitroglycerin | 1983 |
Nitroglycerin and long-acting nitrates in clinical practice.
Topics: Angina Pectoris; Angina Pectoris, Variant; Coronary Vasospasm; Drug Tolerance; Heart Failure; Humans; Myocardial Infarction; Nitrates; Nitroglycerin | 1983 |
Drug interactions I: detection of inorganic nitrite in organic nitrate esters under acidic conditions simulating the human stomach.
Topics: Chemistry, Pharmaceutical; Drug Contamination; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Nitrates; Nitrites; Nitroglycerin; Solvents; Time Factors; Vasodilator Agents | 1983 |
Blood vessel uptake and metabolism of organic nitrates in the rat.
Topics: Animals; Aorta; Blood Vessels; Carbon Radioisotopes; Femoral Vein; Isosorbide Dinitrate; Kinetics; Male; Nitrates; Nitroglycerin; Rats; Rats, Inbred Strains; Time Factors; Vena Cava, Inferior | 1984 |
Nitrates IV. Cardiovascular effects.
Topics: Heart Diseases; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1983 |
Methemoglobin levels produced by organic nitrates in patients with coronary artery disease.
Topics: Aged; Angina Pectoris; Angina, Unstable; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Male; Methemoglobin; Middle Aged; Nitrates; Nitroglycerin | 1984 |
Second North American Conference on Nitroglycerin Therapy: perspectives and mechanisms. Casa de Campo, Dominican Republic, December 7-9,1983.
Topics: Humans; Nitrates; Nitroglycerin | 1984 |
Mechanism of action of nitrates. Role of changes in venous capacitance and in the left ventricular diastolic pressure-volume relation.
Topics: Animals; Cardiac Output; Coronary Circulation; Dogs; Heart Failure; Humans; Nitrates; Nitroglycerin; Stroke Volume; Vasodilation | 1984 |
Nitrates for angina pectoris. A critical review of therapeutic efficacy and tolerance.
Topics: Angina Pectoris; Drug Tolerance; Electrocardiography; Hemodynamics; Humans; Isosorbide Dinitrate; Long-Term Care; Nitrates; Nitroglycerin; Physical Exertion | 1984 |
Pharmacological differentiation between large and small coronary vessels.
Topics: Adenosine; Animals; Calcium; Chlorides; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Nitrates; Nitroglycerin; Potassium; Thiocyanates; Verapamil | 1984 |
Effect on nitroglycerin and other organic nitrates on the in-vitro biosynthesis of arachidonic acid-metabolites in washed human platelets.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Malondialdehyde; Nitrates; Nitroglycerin; Thromboxane B2; Vasodilator Agents | 1984 |
Investigations into the development of tolerance to organic nitrates in conscious dogs.
Topics: Animals; Blood Pressure; Dogs; Drug Tolerance; Female; Hemodynamics; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin; Time Factors | 1984 |
Nitrates in heart failure. Pathophysiological mechanisms and therapeutic applications.
Topics: Cardiac Output; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Hydralazine; Isosorbide Dinitrate; Muscle, Smooth, Vascular; Myocardium; Nitrates; Nitroglycerin; Oxygen Consumption; Pulmonary Wedge Pressure; Vasodilation | 1984 |
Treatment of coronary heart disease with isosorbide mononitrate ('Elantan' 20): a multi-centre study in hospital and general practice.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin | 1984 |
Effects of 2-nicotinamidethyl nitrate (SG-75) and/or nitroglycerin on systemic hemodynamics and coronary blood flow in conscious dogs.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Heart Rate; Hemodynamics; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Vascular Resistance; Vasodilator Agents | 1981 |
[Studies on the relation between collateral development and the effects of antianginal drugs--effects of nitroglycerin and 2-nicotinamidethyl nitrate on collateral circulation (author's transl)].
Topics: Angina Pectoris; Animals; Collateral Circulation; Coronary Circulation; Dogs; Niacinamide; Nicorandil; Nitrates; Nitroglycerin | 1981 |
Effects of a new coronary vasodilator, N-(2-hydroxyethyl)nicotinamide nitrate (SG-75) and nitroglycerin on cardiovascular hemodynamics in young and aged beagle dogs.
Topics: Age Factors; Animals; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Male; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Vasodilator Agents | 1981 |
[Drug therapy of coronary disease. Nitrates in acute and longtime therapy].
Topics: Coronary Disease; Headache; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Time Factors | 1980 |
[Effect on the peripheral circulation during treatment of cardiac insufficiency].
Topics: Blood Circulation; Cardiac Output; Heart; Heart Diseases; Hemodynamics; Humans; Nitrates; Nitroglycerin; Nitroprusside; Oxygen Consumption; Phentolamine; Piperazines; Prazosin; Quinazolines; Vascular Resistance; Vasodilator Agents | 1980 |
[Long-term treatment of coronary disease with nitrates. The prescribed dosage is mostly too low].
Topics: Coronary Disease; Dose-Response Relationship, Drug; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin | 1980 |
Hemodynamic effects of nitrates in chronic heart failure and myocardial infarction.
Topics: Chronic Disease; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Myocardial Infarction; Nitrates; Nitroglycerin; Oxygen Consumption; Vasodilator Agents | 1980 |
[Long-acting nitrate compounds (author's transl)].
Topics: Delayed-Action Preparations; Heart Failure; Humans; Kinetics; Nitrates; Nitroglycerin; Vasodilator Agents | 1980 |
[Are nitrate compounds effective when administered orally? Results of pharmacokinetic and hemodynamic studies].
Topics: Administration, Oral; Hemodynamics; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilator Agents | 1980 |
Nitrate tolerance and dependence. A critical assessment.
Topics: Angina Pectoris; Animals; Dogs; Drug Tolerance; Heart Failure; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Rabbits; Rats; Substance-Related Disorders; Tachyphylaxis; Vasodilator Agents | 1980 |
[Long-term use of nitrates in angina pectoris. Is there a development of tolerance?].
Topics: Administration, Oral; Angina Pectoris; Drug Tolerance; Humans; Nitrates; Nitroglycerin; Occupational Medicine | 1980 |
[Modern aspects of nitro preparation use].
Topics: Adult; Aged; Angina Pectoris; Cardiovascular Agents; Chronic Disease; Coronary Disease; Delayed-Action Preparations; Drug Evaluation; Female; Hemodynamics; Humans; Male; Middle Aged; Nitrates; Nitro Compounds; Nitroglycerin | 1980 |
[Use of nitrates in clinical practice].
Topics: Angina Pectoris; Cardiovascular System; Electrocardiography; Heart Failure; Humans; Myocardial Infarction; Nitrates; Nitroglycerin; Substance-Related Disorders | 1980 |
Verapamil therapy in variant angina pectoris refractory to nitrates.
Topics: Adult; Aged; Angina Pectoris; Angina Pectoris, Variant; Electrocardiography; Ergonovine; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Verapamil | 1981 |
Nitrates, package inserts, and the Food and Drug Administration. A clinical paradox.
Topics: Angina Pectoris; Biological Availability; Delayed-Action Preparations; Drug Labeling; Heart Failure; Humans; Isosorbide Dinitrate; Nitrates; Nitroglycerin; United States; United States Food and Drug Administration; Vasodilator Agents | 1981 |
Enhancement of phentolamine by nitrates in patients with congestive heart failure.
Topics: Blood Pressure; Cardiac Output; Drug Therapy, Combination; Female; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Phentolamine; Stroke Volume | 1981 |
National Institutes of Health Consensus Development Conference Statement. Coronary artery bypass surgery: scientific and clinical aspects.
Topics: Coronary Artery Bypass; Coronary Disease; Decision Making; Electrocardiography; Humans; Myocardial Infarction; National Institutes of Health (U.S.); Nitrates; Nitroglycerin; Patient Education as Topic; Physician-Patient Relations; Quality of Life; United States | 1981 |
A systematic procedure for the identification of post-explosion samples of commercial blasting explosives.
Topics: Chromatography, Gas; Ether; Explosions; Methods; Nitrates; Nitroglycerin; Trinitrotoluene | 1981 |
The nitrites and nitrates.
Topics: Angina Pectoris; Angina Pectoris, Variant; Drug Interactions; Ethanol; Heart Failure; Liver; Mouth Floor; Myocardium; Nitrates; Nitrites; Nitroglycerin | 1982 |
Preload and afterload without anguish: a simplified framework.
Topics: Cardiac Output; Coronary Circulation; Heart Failure; Heart Function Tests; Humans; Hydralazine; Nitrates; Nitroglycerin; Nitroprusside; Prazosin; Pulmonary Wedge Pressure; Stroke Volume; Vascular Resistance; Vasodilator Agents | 1982 |
Managing angina with nitrates.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Angina Pectoris, Variant; Capsules; Delayed-Action Preparations; Humans; Injections, Intravenous; Isosorbide Dinitrate; Mouth Floor; Nitrates; Nitroglycerin; Ointments; Tablets | 1982 |
[Serum nitrate levels in patients with stable angina pectoris treated with sustained-action nitroglycerin preparations].
Topics: Adult; Angina Pectoris; Delayed-Action Preparations; Humans; Male; Middle Aged; Nitrates; Nitroglycerin | 1982 |
Investigations into the role of sulfhydryl groups in the mechanism of action of the nitrates.
Topics: Animals; Chloromercuribenzoates; Dithionitrobenzoic Acid; Dithiothreitol; Dogs; In Vitro Techniques; Muscle, Smooth; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; p-Chloromercuribenzoic Acid; Phenylephrine; Saphenous Vein; Sulfhydryl Compounds | 1982 |
Pharmacokinetic studies of various preparations of glyceryl trinitrate.
Topics: Adult; Blood Pressure; Heart Rate; Humans; Kinetics; Male; Nitrates; Nitrites; Nitroglycerin; Time Factors | 1982 |
Nitrovasodilator-induced relaxation and tolerance development in porcine vena cordis magna: dependence on intact endothelium.
Topics: Animals; Arginine; Cysteine; Dinoprost; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrates; Nitroglycerin; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Substance P; Swine; Vasodilator Agents | 1994 |
Synthesis and pharmacology of a series of new organic nitrate esters.
Topics: Animals; Esters; Hemodynamics; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin; Rabbits; Rats; Rats, Wistar; Structure-Activity Relationship; Vasodilator Agents | 1995 |
Mechanism of vascular relaxation induced by the nitric oxide (NO)/nucleophile complexes, a new class of NO-based vasodilators.
Topics: Animals; Diethylamines; Endothelium, Vascular; Muscle, Smooth, Vascular; Nitrates; Nitric Acid; Nitroglycerin; Nitroprusside; Rabbits; Vasodilation; Vasodilator Agents | 1993 |
Nitric oxide liberating, soluble guanylate cyclase stimulating and vasorelaxing properties of the new nitrate-compound SPM 3672.
Topics: Animals; Aorta, Thoracic; Coronary Vessels; Cyclic GMP; Cysteine; Guanylate Cyclase; Humans; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Rats; Rats, Wistar; Solubility; Swine; Vasodilator Agents | 1993 |
The rationale for nitrates in angina pectoris.
Topics: Angina Pectoris; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Humans; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin; Patient Compliance; Vasodilator Agents | 1995 |
New antianginal nitro esters with reduced hypotensive activity. Synthesis and pharmacological evaluation of 3-[(nitrooxy)alkyl]-2H-1,3-benzoxazin-4(3H)-ones.
Topics: Angina Pectoris; Animals; Benzoxazines; Blood Pressure; Hemodynamics; Hypotension; In Vitro Techniques; Ischemia; Male; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Oxazines; Rabbits; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Vasodilator Agents | 1995 |
GSH-independent denitration of the nitrate ester of a dihydropyridine derivative in rabbit hepatic cytosol.
Topics: Animals; Chemical Fractionation; Cytosol; Dihydropyridines; Dithiothreitol; Glutathione; Glutathione Transferase; Liver; Nitrates; Nitroglycerin; Rabbits | 1995 |
A clinical and in vitro study on the possible interaction of intravenous nitrates with heparin anticoagulation.
Topics: Angina, Unstable; Drug Interactions; Drug Therapy, Combination; Female; Heparin; Humans; In Vitro Techniques; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Partial Thromboplastin Time; Prospective Studies | 1994 |
Influence of endothelium and nitrovasodilators on free thiols and disulfides in porcine coronary smooth muscle.
Topics: Analysis of Variance; Animals; Coronary Vessels; Cysteine; Disulfides; Drug Tolerance; Endothelium, Vascular; Histocytochemistry; In Vitro Techniques; Isosorbide Dinitrate; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Sulfhydryl Compounds; Swine; Vasodilator Agents | 1993 |
Primary nitrate tolerance in diabetes mellitus.
Topics: Acetylcholine; Arterioles; Diabetes Mellitus, Type 2; Drug Tolerance; Endothelium, Vascular; Forearm; Humans; Models, Cardiovascular; Muscle, Smooth, Vascular; Muscles; Nitrates; Nitroglycerin; Reference Values; Vasodilation | 1994 |
Effect of nicorandil on post-ischaemic contractile dysfunction in the heart: roles of its ATP-sensitive K+ channel opening property and nitrate property.
Topics: Adenosine Triphosphate; Animals; Glyburide; Hemodynamics; Infusions, Intravenous; Ion Channel Gating; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardial Stunning; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Potassium Channels; Premedication; Rabbits; Vasodilator Agents | 1993 |
Nitrate tolerance in vivo is not associated with depletion of arterial or venous thiol levels.
Topics: Acetylcysteine; Animals; Arteries; Drug Tolerance; Female; Nitrates; Nitroglycerin; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Reference Values; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Veins | 1994 |
[Tolerance and pseudo-tolerance following administration of nitrates].
Topics: Drug Tolerance; Humans; Nitrates; Nitroglycerin | 1993 |
[The efficacy of nitrate solutions in emergency states].
Topics: Angina Pectoris; Drug Evaluation; Emergencies; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Solutions | 1993 |
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds.
Topics: Animals; Brain; Cell Death; Cells, Cultured; Cysteine; Free Radicals; Molsidomine; Neurons; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxidation-Reduction; Rats; Receptors, N-Methyl-D-Aspartate; S-Nitrosothiols; Superoxides | 1993 |
Interactions of nitrovasodilators and atrial natriuretic peptide in isolated dog coronary arteries.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic GMP; Dinoprost; Dogs; Epoprostenol; Female; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Nitroprusside; Oxyhemoglobins; Papaverine; Platelet Aggregation Inhibitors; Vasodilator Agents | 1993 |
In support of nitrate ointment for patients with acute myocardial infarction.
Topics: Administration, Cutaneous; Humans; Myocardial Infarction; Nitrates; Nitroglycerin; Ointments | 1993 |
Nitroglycerin metabolism in vascular tissue: role of glutathione S-transferases and relationship between NO. and NO2- formation.
Topics: Animals; Carotid Arteries; Dogs; Free Radicals; Glutathione Transferase; In Vitro Techniques; Nitrates; Nitrites; Nitroglycerin | 1993 |
Human endothelial cells bioactivate organic nitrates to nitric oxide: implications for the reinforcement of endothelial defence mechanisms.
Topics: Biotransformation; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Humans; Isosorbide Dinitrate; Nitrates; Nitric Oxide; Nitroglycerin; Platelet Aggregation; Time Factors | 1995 |
Activation of guanylate cyclase in the guinea-pig trachea reduces contractile responses of the smooth muscle.
Topics: Acetylcholine; Animals; Ascorbic Acid; Carcinogens; Electric Stimulation; Guanylate Cyclase; Guinea Pigs; Histamine; Male; Muscle Contraction; Muscle, Smooth; Nitrates; Nitroglycerin; Trachea; Vasodilator Agents | 1995 |
Specificity of different organic nitrates to elicit NO formation in rabbit vascular tissues and organs in vivo.
Topics: Animals; Aorta; Blood Vessels; Cysteine; Cytochrome P-450 Enzyme System; Dipeptides; Electron Spin Resonance Spectroscopy; Guanylate Cyclase; In Vitro Techniques; Isometric Contraction; Isosorbide Dinitrate; Kidney; Liver; Muscle Relaxation; Nitrates; Nitric Oxide; Nitroglycerin; Rabbits; Sensitivity and Specificity; Solubility; Sulfhydryl Compounds; Vasodilator Agents; Venae Cavae | 1995 |
Nitrate tolerance impairs nitric oxide-mediated vasodilation in vivo.
Topics: Acetylcholine; Acetylcysteine; Animals; Arginine; Drug Tolerance; Female; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Nitroprusside; Rats; Rats, Wistar; Vasodilation | 1996 |
Evaluation of nitric oxide formation from nitrates in pig coronary arteries.
Topics: Animals; Coronary Vessels; Cysteine; Glutathione Transferase; In Vitro Techniques; Isosorbide Dinitrate; Liver; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Swine; Vasodilation | 1996 |
ITF 296, a new endothelium-independent vasodilator: comparison with nitroglycerin and isosorbide dinitrate.
Topics: Animals; Benzoxazines; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemodynamics; Isosorbide Dinitrate; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Oxazines; Vasodilator Agents | 1995 |
Effect of the new nitrate ester ITF 296 on coronary and systemic hemodynamics in the conscious dog: comparison with nitroglycerin and nicorandil.
Topics: Animals; Benzoxazines; Coronary Circulation; Coronary Vessels; Dogs; Female; Hemodynamics; Injections, Intravenous; Male; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Oxazines; Vasodilator Agents | 1995 |
Effect of ITF 296 on total effective vascular compliance in the anesthetized dog under autonomic blockade.
Topics: Anesthesia; Animals; Autonomic Nerve Block; Benzoxazines; Blood Pressure; Dogs; Female; Hemodynamics; Male; Molsidomine; Muscle Tonus; Nitrates; Nitroglycerin; Oxazines; Vascular Resistance; Vasodilator Agents | 1995 |
The nitrate ester ITF 296 relaxes isolated canine arteries and veins.
Topics: Animals; Arteries; Benzoxazines; Dogs; Electrophysiology; Endothelium, Vascular; Female; In Vitro Techniques; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Oxazines; Vasodilator Agents; Veins | 1995 |
Mechanism of ITF 296-induced vasorelaxation compared to nitroglycerin and isosorbide dinitrate: relationship between relaxation of rabbit aorta and tissue cGMP.
Topics: Animals; Aorta, Thoracic; Benzoxazines; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Oxazines; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
In vivo nitrate tolerance is not associated with reduced bioconversion of nitroglycerin to nitric oxide.
Topics: Animals; Blood Vessels; Dose-Response Relationship, Drug; Drug Tolerance; Female; Infusions, Intravenous; Nitrates; Nitric Oxide; Nitroglycerin; Rats; Rats, Wistar; Spin Trapping; Time Factors | 1996 |
Isosorbide nitrates, nitroglycerin, and sodium nitroprusside induce vasodilation concomitantly with inhibition of carbonic anhydrase I in erythrocytes.
Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Coronary Disease; Coronary Vessels; Erythrocytes; Humans; Nitrates; Nitroglycerin; Nitroprusside; Rabbits; Vasodilation; Vasodilator Agents | 1997 |
Investigation of role for oxidant stress in vascular tolerance development to glyceryl trinitrate in vitro.
Topics: Animals; Aorta; Free Radical Scavengers; In Vitro Techniques; Male; Nitrates; Nitroglycerin; Oxidative Stress; Rats; Rats, Wistar; Superoxides; Vasodilator Agents | 1997 |
Biodegradation of glyceryl trinitrate by Penicillium corylophilum Dierckx.
Topics: Biodegradation, Environmental; Biomass; Equipment Contamination; Glucose; Nitrates; Nitroglycerin; Penicillium; Water | 1997 |
[Clinical and biochemical manifestations of the effects of nitro esters on workers].
Topics: Adult; Air Pollutants, Occupational; Esters; Female; Humans; Male; Maximum Allowable Concentration; Middle Aged; Nitrates; Nitroglycerin; Occupational Diseases; Occupations; Prostaglandins | 1997 |
Treatment of medically and surgically refractory angina pectoris with high thoracic epidural analgesia: initial clinical experience.
Topics: Adrenergic beta-Antagonists; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Anesthetics, Local; Angina Pectoris; Angioplasty, Balloon, Coronary; Anticoagulants; Bupivacaine; Calcium Channel Blockers; Cardiac Output, Low; Coronary Artery Bypass; Coronary Disease; Critical Care; Female; Heparin; Humans; Intra-Aortic Balloon Pumping; Male; Middle Aged; Nitrates; Nitroglycerin; Patient Discharge; Radiography, Interventional; Recurrence; Retrospective Studies; Survival Rate; Thoracic Vertebrae; Tomography, X-Ray Computed; Vasodilator Agents | 1997 |
Nitroglycerin tolerance at the platelet level in patients with angina pectoris.
Topics: Administration, Sublingual; Angina Pectoris; Angina, Unstable; Blood Platelets; Drug Tolerance; Guanylate Cyclase; Humans; Infusions, Intravenous; Nitrates; Nitroglycerin; Nitroprusside; Platelet Aggregation | 1997 |
Long-lasting abnormalities in cardiac sympathetic nervous system in patients with coronary spastic angina: quantitative analysis with iodine 123 metaiodobenzylguanidine myocardial scintigraphy.
Topics: 3-Iodobenzylguanidine; Acetylcholine; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Vasospasm; Coronary Vessels; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Iodine Radioisotopes; Iodobenzenes; Male; Middle Aged; Nitrates; Nitroglycerin; Radiopharmaceuticals; Risk Factors; Sympathetic Nervous System; Sympatholytics; Tachycardia, Ventricular; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents | 1997 |
Formation of the NO donors glyceryl mononitrate and glyceryl mononitrite from the reaction of peroxynitrite with glycerol.
Topics: Animals; Aorta; Glycerol; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Oxidants; Rabbits; Vasodilator Agents | 1997 |
Extra-pulmonary effects of inhaled nitric oxide in swine with and without phenylephrine.
Topics: Administration, Inhalation; Animals; Diuresis; Female; Glomerular Filtration Rate; Hemodynamics; Hypertension; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Partial Pressure; Phenylephrine; Renal Circulation; Swine; Vasodilator Agents | 1997 |
No cross-tolerance between S-nitrosocaptopril and nitroglycerin in dog coronary arteries in vivo.
Topics: Aldosterone; Animals; Captopril; Coronary Circulation; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Female; Hemodynamics; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Nitrates; Nitric Oxide; Nitroglycerin; Norepinephrine; Peptidyl-Dipeptidase A; Renin; Vasodilator Agents | 1998 |
Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions.
Topics: Animals; Cattle; Enzyme Inhibitors; Kinetics; NAD; Nitrates; Nitric Oxide; Nitroglycerin; Oxygen; Oxypurinol; Sodium Nitrite; Triazines; Xanthine Oxidase | 1998 |
Vitamin C attenuates nitrate tolerance independently of its antioxidant effect.
Topics: Animals; Antioxidants; Ascorbic Acid; Cyclic GMP; Drug Resistance; LLC-PK1 Cells; Nitrates; Nitrogen Oxides; Nitroglycerin; Spermine; Swine | 1998 |
Detection of superoxide radicals and peroxynitrite by 1-hydroxy-4-phosphonooxy-2,2,6,6-tetramethylpiperidine: quantification of extracellular superoxide radicals formation.
Topics: Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Kinetics; Molecular Structure; Nitrates; Nitroglycerin; Organophosphates; Piperidines; Pyrrolidines; Spin Labels; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1998 |
Formation of reactive oxygen species by pentaerithrityltetranitrate and glyceryl trinitrate in vitro and development of nitrate tolerance.
Topics: Animals; Blood Platelets; Cells, Cultured; Cyclic GMP; Drug Tolerance; Endothelium, Vascular; Hydroxyl Radical; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Spin Trapping; Superoxides; Swine | 1998 |
Aerobic growth on nitroglycerin as the sole carbon, nitrogen, and energy source by a mixed bacterial culture.
Topics: Bacteria; Biodegradation, Environmental; Chromatography, High Pressure Liquid; Culture Media; Kinetics; Nitrates; Nitrites; Nitroglycerin; Sewage; Substrate Specificity | 1998 |
Efficacy and rebound phenomenon related to intermittent nitroglycerin therapy for the prevention of nitrate tolerance.
Topics: Administration, Cutaneous; Adult; Cyclic GMP; Drug Tolerance; Female; Forearm; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Vasodilation; Vasodilator Agents | 1998 |
Interaction between capsaicin and nitrate tolerance in isolated guinea-pig heart.
Topics: Animals; Arginine; Capsaicin; Coronary Circulation; Drug Interactions; Drug Tolerance; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitroglycerin; Perfusion; Vasodilator Agents | 1999 |
Reaction of organic nitrate esters and S-nitrosothiols with reduced flavins: a possible mechanism of bioactivation.
Topics: Biotransformation; Flavin Mononucleotide; Glutathione; Glutathione Disulfide; Muscle, Smooth, Vascular; NAD; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitro Compounds; Nitroglycerin; Nitroso Compounds; Nitrous Oxide; Oxidation-Reduction; Sulfhydryl Compounds; Vasodilation | 1999 |
Increased nitric oxide concentrations in posterior hypothalamus and central sympathetic function on nitrate tolerance following subcutaneous nitroglycerin.
Topics: Animals; Blood Vessels; Hypothalamus, Posterior; Injections, Subcutaneous; Male; Nitrates; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasodilator Agents | 1999 |
Evidence for a causal role of the renin-angiotensin system in nitrate tolerance.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Bosentan; Dose-Response Relationship, Drug; Drug Tolerance; Endothelium, Vascular; Female; Gene Expression; Losartan; Luminescent Measurements; Male; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitrates; Nitric Oxide; Nitroglycerin; Peptidyl-Dipeptidase A; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Sulfonamides; Superoxides; Vasoconstriction; Vasodilation; Vasodilator Agents | 1999 |
Nitrate resistance in platelets from patients with stable angina pectoris.
Topics: Adenosine Diphosphate; Adult; Aged; Angina Pectoris; Blood Platelets; Drug Resistance; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values | 1999 |
Comparison of glyceryl trinitrate-induced with pentaerythrityl tetranitrate-induced in vivo formation of superoxide radicals: effect of vitamin C.
Topics: Animals; Antioxidants; Ascorbic Acid; Female; Free Radical Scavengers; Hemodynamics; Male; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Rabbits; Superoxides; Vasodilator Agents | 1999 |
Vascular peroxynitrite formation during organic nitrate tolerance.
Topics: Animals; Aorta, Thoracic; Blood Proteins; Drug Tolerance; Immunohistochemistry; Male; Nitrates; Nitroglycerin; Rats; Rats, Sprague-Dawley; Tyrosine; Vasodilator Agents | 1999 |
Medical therapy for stable angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Humans; Meta-Analysis as Topic; Nitrates; Nitroglycerin; Randomized Controlled Trials as Topic; Recurrence; Reproducibility of Results; Treatment Outcome; Vasodilator Agents | 1999 |
Absence of nitrate tolerance after long-term treatment with ramipril: an endothelium-dependent mechanism.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; Losartan; Male; Nitrates; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Ramipril; Rats; Rats, Wistar; Superoxides; Time Factors; Vasodilator Agents | 1999 |
Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Angiotensin II; Antihypertensive Agents; Diabetes Mellitus, Type 1; Epoprostenol; Female; Fetus; Humans; In Vitro Techniques; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Reactive Oxygen Species; Tyrosine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Effects of the flavoprotein inhibitor, diphenyleneiodonium sulfate, on ex vivo organic nitrate tolerance in the rat.
Topics: Animals; Aorta, Thoracic; Biotransformation; Blotting, Northern; Drug Tolerance; Enzyme Inhibitors; Flavoproteins; Glutathione; Isosorbide Dinitrate; Male; Microsomes; Muscle, Smooth, Vascular; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; Nitroso Compounds; Onium Compounds; Prodrugs; Rats; Rats, Sprague-Dawley; S-Nitrosoglutathione; Stereoisomerism; Superoxides; Vasodilator Agents | 2000 |
Arginine and nitrate tolerance.
Topics: Animals; Arginine; Drug Tolerance; Humans; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin | 2000 |
[Role of nitrates in the treatment of ischemia].
Topics: Angina Pectoris; Coronary Disease; Emergencies; Humans; Hypotension, Orthostatic; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Time Factors; Vasodilator Agents | 2000 |
Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Endothelin-1; Hypertension, Renovascular; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth, Vascular; Naproxen; Nitrates; Nitric Oxide Donors; Nitrites; Nitroglycerin; Nitroprusside; Phenylephrine; Rats; Rats, Wistar; Renal Artery; Thromboxane B2 | 2000 |
Antiplatelet activity of Staphylococcus aureus lipoteichoic acid is mediated through a cyclic AMP pathway.
Topics: Alprostadil; Blood Platelets; Blood Proteins; Calcium Signaling; Collagen; Cyclic AMP; Cyclic GMP; Cytokines; Enzyme Induction; Gram-Positive Bacteria; Humans; Lipopolysaccharides; Molecular Weight; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroglycerin; Phorbol 12,13-Dibutyrate; Phosphorylation; Platelet Aggregation Inhibitors; Protein Kinase C; Protein Processing, Post-Translational; Second Messenger Systems; Shock, Septic; Staphylococcus aureus; Teichoic Acids | 2000 |
Comparison of zofenopril and lisinopril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE-inhibitors in experimental heart failure.
Topics: Acetylcholine; Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Calcimycin; Captopril; Endothelium, Vascular; Heart Diseases; In Vitro Techniques; Lisinopril; Male; Myocardial Infarction; Nitrates; Nitrites; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Wistar; Sodium Nitrite; Sulfhydryl Compounds; Vasodilation; Vasodilator Agents | 2000 |
A novel nitrate ester reverses the cognitive impairment caused by scopolamine in the Morris water maze.
Topics: Animals; Cognition Disorders; Guanylate Cyclase; Male; Maze Learning; Muscarinic Antagonists; Nitrates; Nitroglycerin; Propane; Rats; Rats, Long-Evans; Scopolamine; Vasodilator Agents | 2000 |
Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Apolipoproteins E; Biopterins; Calcimycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Ionophores; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroglycerin; Pteridines; Pterins; Superoxides; Vasodilation; Vasodilator Agents | 2001 |
Two possible mechanisms underlying nitrate tolerance in monkey coronary arteries.
Topics: Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic GMP; Drug Interactions; Drug Tolerance; Female; Macaca; Male; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Vasodilation; Vasodilator Agents | 2001 |
Effects of nitrovasodilators on the human fetal-placental circulation in vitro.
Topics: Adolescent; Adult; Antioxidants; Arteries; Chorion; Cysteine; Female; Fetus; Gestational Age; Glutathione; Humans; In Vitro Techniques; Nitrates; Nitroglycerin; Nitroprusside; Nitroso Compounds; Oxygen; Penicillamine; Placenta; Pregnancy; S-Nitrosoglutathione; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 2001 |
Effects of nitric oxide on normal and ischemic cochlea of the guinea pig.
Topics: Animals; Catalase; Cell Count; Cochlea; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hair Cells, Auditory, Inner; Hair Cells, Auditory, Outer; Ischemia; Microinjections; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroglycerin; Nitroso Compounds; Perilymph; S-Nitrosothiols; Sensory Receptor Cells; Superoxide Dismutase | 2001 |
The influence of nitric oxide donors on the responses to nitrergic nerve stimulation in the mouse duodenum.
Topics: Animals; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Enzyme Inhibitors; Ethylmaleimide; Female; Hemoglobins; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroglycerin; Nitroprusside; Oxadiazoles; Quinoxalines; Thiazines | 2001 |
Old yellow enzyme: reduction of nitrate esters, glycerin trinitrate, and propylene 1,2-dinitrate.
Topics: Catalysis; Esters; Flavins; Kinetics; NADPH Dehydrogenase; Nitrates; Nitroglycerin; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Propylene Glycols; Riboflavin | 2001 |
Prostaglandins and nitric oxide mediate superoxide-induced myocardial contractile dysfunction in isolated rat hearts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aspartate Aminotransferases; Colforsin; Enzyme Inhibitors; Heart; Myocardial Contraction; Myocardium; Nitrates; Nitric Acid; Nitroarginine; Nitroglycerin; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Prostaglandins; Quinoxalines; Rats; Superoxides; Thromboxane A2; Vasodilator Agents | 2001 |
In vitro activation of soluble guanylyl cyclase and nitric oxide release: a comparison of NO donors and NO mimetics.
Topics: Animals; Aorta; Cysteine; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Glutathione; Guanylate Cyclase; Hydrazines; Indazoles; Molecular Mimicry; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Nitroso Compounds; Penicillamine; Rats; S-Nitrosoglutathione; Solubility | 2001 |
Escape from tolerance of organic nitrate by induction of cytochrome P450.
Topics: Animals; Blood Pressure; Blotting, Western; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Drug Tolerance; Enzyme Induction; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydrazines; Immunohistochemistry; Interleukin-1; Isoenzymes; Isosorbide Dinitrate; Kinetics; Male; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroglycerin; Nitroprusside; Rats; Rats, Wistar | 2001 |
Lack of critical involvement of endothelial nitric oxide synthase in vascular nitrate tolerance in mice.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroglycerin; Vasodilation; Vasodilator Agents | 2002 |
Mechanisms of nitric oxide generation from nitroglycerin and endogenous sources during hypoxia in vivo.
Topics: Animals; Hypoxia; Lung; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroglycerin; Perfusion; Rabbits; Vasodilator Agents | 2002 |
Effects of nitroglycerin on soluble guanylate cyclase: implications for nitrate tolerance.
Topics: Enzyme Activation; Guanylate Cyclase; Nitrates; Nitroglycerin; Oxidation-Reduction; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Spectrum Analysis | 2002 |
Diminished arteriolar responses in nitrate tolerance involve ROS and angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Drug Tolerance; Free Radical Scavengers; Losartan; Male; Metalloporphyrins; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Vasodilation | 2002 |
The effect of oxidative stress on endothelium-dependent and nitric oxide donor-induced relaxation: implications for nitrate tolerance.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Glutathione; In Vitro Techniques; Male; Muscle Relaxation; Nitrates; Nitric Oxide Donors; Nitroglycerin; Oxidative Stress; Pyrogallol; Rats; Rats, Wistar | 2002 |
Penile erectile responses to cavernous nerve stimulation in rats are not affected by nitrate tolerance.
Topics: Animals; Blood Pressure; Drug Tolerance; Electric Stimulation; Isosorbide Dinitrate; Male; Nitrates; Nitroglycerin; Penile Erection; Rats | 2002 |
Mechanisms underlying nitroglycerin-induced superoxide production in platelets: some insight, more questions.
Topics: Antioxidants; Ascorbic Acid; Blood Platelets; Drug Tolerance; Heart Diseases; Humans; NADPH Oxidases; Nitrates; Nitric Oxide; Nitroglycerin; Platelet Aggregation Inhibitors; Superoxides; Vasodilator Agents | 2002 |
Inhibition of lipid peroxidation in synaptosomes and liposomes by nitrates and nitrites.
Topics: Amyl Nitrite; Animals; Antioxidants; Cerebral Cortex; Egg Yolk; Lipid Peroxidation; Liposomes; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroglycerin; Phospholipids; Rats; Rats, Sprague-Dawley; Synaptosomes; Thiobarbituric Acid Reactive Substances | 2002 |
Bioactivation of nitroglycerin and vasomotor response to nitric oxide are impaired in cirrhotic rat livers.
Topics: Animals; Liver; Liver Cirrhosis, Experimental; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroglycerin; Organ Size; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 2002 |
Biological monitoring of nitroglycerin exposure by urine analysis.
Topics: Drug Industry; Environmental Monitoring; Firearms; Gas Chromatography-Mass Spectrometry; Glycerol; Humans; Nitrates; Nitroglycerin; Occupational Exposure | 2002 |
Neuroprotection against ischemic brain injury conferred by a novel nitrate ester.
Topics: Animals; Blood Pressure; Brain; Brain Ischemia; Cyclic GMP; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Infarction, Middle Cerebral Artery; Muscle Relaxation; Muscle, Smooth, Vascular; Neuroprotective Agents; Nitrates; Nitroglycerin; Propane; Rats; Vasodilator Agents | 2002 |
Hormone replacement effects on endothelial function measured in the forearm resistance artery in normocholesterolemic and hypercholesterolemic postmenopausal women.
Topics: Arteries; Blood Flow Velocity; Cholesterol, HDL; Cholesterol, LDL; Endothelium, Vascular; Estradiol; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Forearm; Humans; Hypercholesterolemia; Hyperemia; Lipids; Medroxyprogesterone Acetate; Middle Aged; Nitrates; Nitrites; Nitroglycerin; Peptidyl-Dipeptidase A; Plethysmography; Postmenopause; Vascular Resistance | 2002 |
Cardiac arrest related to coronary spasm in patients with variant angina: a three-case study.
Topics: Amiodarone; Angina Pectoris, Variant; Anti-Arrhythmia Agents; Aspirin; Calcium Channel Blockers; Cardiovascular Agents; Coronary Angiography; Diltiazem; Electrocardiography; Female; Follow-Up Studies; Heart Arrest; Heart Block; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Pacemaker, Artificial; Platelet Aggregation Inhibitors; Spasm; Time Factors; Vasodilator Agents; Ventricular Fibrillation | 2002 |
Determination of nitroglycerin and its dinitrate metabolites in urine by gas chromatography-mass spectrometry as potential biomarkers for occupational exposure.
Topics: Biomarkers; Gas Chromatography-Mass Spectrometry; Humans; Nitrates; Nitroglycerin; Occupational Exposure; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2002 |
Effect of L-arginine or nitroglycerine during deep hypothermic circulatory arrest in neonatal lambs.
Topics: Animals; Animals, Newborn; Arginine; Heart Arrest, Induced; Hypothermia, Induced; Lung Compliance; Malondialdehyde; Nitrates; Nitrites; Nitroglycerin; Pulmonary Circulation; Sheep; Stroke Volume; Vascular Resistance | 2003 |
Organic nitrate tolerance is induced by degradation of some cytochrome P450 isoforms.
Topics: Animals; Blotting, Western; Cytochrome P-450 CYP1A2; Humans; Immunohistochemistry; Isosorbide Dinitrate; Male; Nitrates; Nitric Oxide; Nitroglycerin; Protein Isoforms; Rats; Rats, Wistar; Time Factors; Vasodilator Agents | 2002 |
Synthesis and collateral dilator activity of nitroxyalkylamides having direct or latent sulfhydryl moieties.
Topics: Animals; Area Under Curve; Carotid Arteries; Collateral Circulation; Cysteine; Dogs; Drug Tolerance; Injections, Intravenous; Male; Nitrates; Nitric Oxide Donors; Nitroglycerin; Sulfhydryl Compounds; Thiazoles; Vasodilator Agents | 2003 |
NO donors, part 8 [1]: synthesis and vasodilating activities of substituted benzylnitrates compared to cyclohexylmethylnitrate and GTN.
Topics: Animals; Benzyl Compounds; Coronary Vessels; Cyclohexanes; Endothelium, Vascular; Nitrates; Nitric Oxide Donors; Nitroglycerin; Swine; Vasodilator Agents | 2003 |
Melatonin inhibits nitrate tolerance in isolated coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Isometric Contraction; Isoproterenol; Melatonin; Muscle, Smooth, Vascular; Naphthalenes; Nitrates; Nitroglycerin; Receptors, Melatonin; Swine; Tachyphylaxis; Time Factors; Tryptamines; Vasoconstriction; Vasodilation; Vasodilator Agents | 2003 |
[Contribution to the therapy of angina pectoris syndrome with myocardon].
Topics: Aminophylline; Angina Pectoris; Atropine; Drug Combinations; Humans; Nitrates; Nitroglycerin; Papaverine; Phenobarbital | 1953 |
[Stenocardiac attacks in workers employed in production of dynamite with nitroglycols].
Topics: Angina Pectoris; Employment; Ethylene Glycols; Ethylenes; Humans; Nitrates; Nitroglycerin | 1954 |
Long-acting coronary vasodilator drugs: metamine, paveril, nitroglyn and peritrate.
Topics: Blood Vessels; Humans; Isoquinolines; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Quinolines; Vasodilator Agents | 1955 |
[Nitroglycerin test in electrocardiographic diagnosis of coronary disease].
Topics: Coronary Disease; Electrocardiography; Humans; Nitrates; Nitroglycerin | 1958 |
[The effort test & the nitroglycerin test in the aged].
Topics: Aged; Aging; Electrocardiography; Humans; Nitrates; Nitroglycerin | 1959 |
[Photoplethysmographic research on the effects of nitroglycerin in the aged].
Topics: Aged; Heart; Humans; Nitrates; Nitroglycerin | 1959 |
[Changes induced in the electrocardiogram of the aged by the administration of nitroglycerin].
Topics: Aged; Aging; Electrocardiography; Humans; Nitrates; Nitroglycerin; Pharmaceutical Preparations | 1959 |
[Review of pharmacologic data and therapeutic schemes on the subject of coronary pathology].
Topics: Chromones; Coronary Disease; Humans; Monoamine Oxidase Inhibitors; Nitrates; Nitroglycerin; Papaverine; Prenylamine; Vasodilator Agents; Xanthines | 1963 |
Determination of the oil/water distribution coefficients of glyceryl trinitrate and two similar nitrate esters.
Topics: Esters; Nitrates; Nitrites; Nitrogen Oxides; Nitroglycerin | 1963 |
Clinical evaluation of sublingual nitrates. Onset and duration of action of nitroglycerin and isosorbide dinitrate.
Topics: Angina Pectoris; Humans; Isosorbide Dinitrate; Nitrates; Nitrites; Nitroglycerin; Vasodilator Agents | 1963 |
COMPARATIVE EFFECTIVENESS OF ORGANIC NITRATES: AN OBJECTIVE STUDY IN MAN.
Topics: Coronary Disease; Electrocardiography; Erythrityl Tetranitrate; Humans; Male; Nitrates; Nitrites; Nitroglycerin; Pentaerythritol Tetranitrate; Schizophrenia; Vasodilator Agents | 1963 |
[ORGANIC NITRATES AND THEIR USE IN STENOCARDIA].
Topics: Angina Pectoris; Nitrates; Nitroglycerin | 1963 |
USE OF NITRATE AND NITRITE VASODILATORS BY GLAUCOMATOUS PATIENTS.
Topics: Angina Pectoris; Glaucoma; Humans; Nitrates; Nitrites; Nitroglycerin; Toxicology; Vasodilator Agents | 1964 |
SENSITIVITY OF COLOR TESTS FOR NITRITES, NITRATES, AND GLYCERYL TRINITRATE. I. SOLUTIONS IN DISTILLED WATER.
Topics: Chemistry, Pharmaceutical; Color; Excipients; Indicators and Reagents; Nitrates; Nitrites; Nitroglycerin; Pharmacy; Research; Solutions | 1964 |
STEREO-ISOMERIC NITRATES IN THE TREATMENT OF ANGINA PECTORIS.
Topics: Angina Pectoris; Biomedical Research; Chlorothiazide; Dipyridamole; Drug Therapy; Erythrityl Tetranitrate; Exercise Test; Furans; Humans; Nitrates; Nitrites; Nitroglycerin; Vasodilator Agents | 1965 |
PREVENTION OF CORONARY THROMBOSIS: CLINICAL OBSERVATIONS FOR 1 TO 10 YEARS.
Topics: Biomedical Research; Coronary Disease; Coronary Thrombosis; Drug Therapy; Humans; Niacin; Nicotinic Acids; Nitrates; Nitroglycerin; Papaverine; Pentaerythritol Tetranitrate; Preventive Medicine; Theobromine; Thiamine; Toxicology; Vasodilator Agents | 1965 |
The effect of nitroglycerine upon the cardiovascular system.
Topics: Cardiovascular System; Humans; Nitrates; Nitroglycerin | 1955 |
Role of mitochondrial aldehyde dehydrogenase in nitrate tolerance.
Topics: Aldehyde Dehydrogenase; Animals; Aorta; Biotransformation; Drug Interactions; Enzyme Inhibitors; Hydrazines; Liver; Mitochondria; Nitrates; Nitrogen Oxides; Nitroglycerin; Rabbits; Rats; Vasodilation | 2003 |
Nitrate tolerance in hypertension: new insight into a century-old problem.
Topics: Animals; Blood Vessels; Calcium Signaling; Drug Tolerance; Humans; Hypertension; Nitrates; Nitroglycerin; Potassium Channels, Calcium-Activated; Signal Transduction; Vasodilation | 2003 |
Continuous administration of organic nitrate decreases hepatic cytochrome P450.
Topics: Animals; Blotting, Western; Catalase; Cytochrome P-450 Enzyme System; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Isosorbide Dinitrate; Liver; Male; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroglycerin; Rats; Rats, Wistar | 2004 |
First aid for a hypertensive crisis.
Topics: Administration, Sublingual; Depression; Female; Humans; Hypertension; Middle Aged; Monoamine Oxidase Inhibitors; Nitrates; Nitroglycerin; Vasodilator Agents | 2003 |
Therapy with nitrates: increasing evidence of vascular toxicity.
Topics: Cardiovascular Diseases; Drug Tolerance; Endothelium, Vascular; Humans; Nitrates; Nitroglycerin; Reactive Oxygen Species; Vasodilator Agents | 2003 |
Nitrate tolerance, oxidative stress, and mitochondrial function: another worrisome chapter on the effects of organic nitrates.
Topics: Free Radicals; Humans; Mitochondria; Nitrates; Nitroglycerin; Oxidative Stress | 2004 |
Alkyl nitrites, XVI. Comparative depressor response of octyl nitrite and glyceryl trinitrate.
Topics: Humans; Nitrates; Nitrites; Nitroglycerin | 1951 |
Tablets of glyceryl trinitrate.
Topics: Nitrates; Nitroglycerin; Tablets | 1951 |
Experimental poisoning of cattle and sheep with dynamite.
Topics: Animals; Cattle; Methemoglobinemia; Nitrates; Nitroglycerin; Sheep; Sheep, Domestic | 1952 |
Uncontrolled hypertension, uncompensated type II diabetes, and smoking have different patterns of vascular dysfunction.
Topics: Adult; Blood Flow Velocity; Cyclic GMP; Diabetes Mellitus, Type 2; Endothelium, Vascular; Humans; Hyperemia; Hypertension; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Smoking; Thromboxane B2; Vasodilation; Vasodilator Agents | 2004 |
Direct demonstration of nitric oxide formation in organs of rabbits treated by transdermal glyceryl trinitrate using an in vivo spin trapping technique.
Topics: Administration, Cutaneous; Animals; Aorta, Thoracic; Blood Pressure; Dosage Forms; Ferrous Compounds; Heart Rate; Heart Ventricles; Hemoglobins; Injections, Intravenous; Kidney; Liver; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Organ Specificity; Rabbits; Sorbitol; Spin Labels; Spin Trapping; Spleen; Thiocarbamates; Time Factors; Vasodilator Agents; Vena Cava, Inferior | 2003 |
Prazosin potentiates the acute hypotensive effects of nitroglycerin but does not attenuate nitrate tolerance in normal conscious rats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Drug Synergism; Drug Tolerance; Hypotension; Injections, Intravenous; Male; Nitrates; Nitroglycerin; Prazosin; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2004 |
Development of insulin resistance by nitrate tolerance in conscious rabbits.
Topics: Animals; Blood Pressure; Drug Tolerance; Glucose; Glucose Clamp Technique; Heart Rate; Insulin Resistance; Male; Nitrates; Nitric Oxide Donors; Nitroglycerin; Rabbits; Vasodilator Agents | 2004 |
Secondary electrospray ionization-ion mobility spectrometry for explosive vapor detection.
Topics: Azetidines; Chlorine Compounds; Environmental Monitoring; Explosions; Gases; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Temperature; Time Factors | 2004 |
Tolerance induction during therapy with long-acting nitrates: how extensive is the "collateral damage"?
Topics: Angina Pectoris; Delayed-Action Preparations; Drug Tolerance; Humans; In Vitro Techniques; Isosorbide Dinitrate; Nitrates; Nitric Oxide Donors; Nitroglycerin | 2004 |
Continuous treatment with organic nitrate affects hepatic cytochrome P450.
Topics: Animals; Blotting, Western; Cytochrome P-450 Enzyme System; Drug Tolerance; Isosorbide Dinitrate; Liver; Male; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitrites; Nitroglycerin; Protein Isoforms; Rats; Rats, Wistar | 2004 |
Synthesis and ocular effects of imidazole nitrolic acids.
Topics: Animals; Aqueous Humor; Cyclic GMP; Drug Design; Imidazoles; Iris; Models, Molecular; Molecular Structure; Nitrates; Nitrites; Nitroglycerin; Swine | 2005 |
Effect of intravenous nitroglycerin therapy on erythrocyte antioxidant enzymes.
Topics: Antioxidants; Catalase; Erythrocytes; Female; Glutathione Peroxidase; Humans; Infusions, Intravenous; Male; Middle Aged; Nitrates; Nitroglycerin; Sulfhydryl Compounds | 2005 |
Nitrate tolerance aggravates postischemic myocardial apoptosis and impairs cardiac functional recovery after ischemia.
Topics: Adaptation, Physiological; Animals; Apoptosis; Blood Pressure; Caspase 3; Creatine Kinase; Dietary Supplements; Enzyme Activation; Glutathione; Heart Rate; Heart Ventricles; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Nitrates; Nitroglycerin; Rats; Recovery of Function; Tyrosine; Vasodilation | 2005 |
Nitrate-based vasodilators inhibit multiple vascular aldehyde dehydrogenases.
Topics: Aldehyde Dehydrogenase; Aldehydes; Animals; Blotting, Western; Humans; Immunohistochemistry; In Vitro Techniques; Inactivation, Metabolic; Isoenzymes; Male; Muscle, Smooth, Vascular; Myocardium; Nitrates; Nitroglycerin; Nitroprusside; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2005 |
Platelet nitrate responsiveness in fasting and postprandial type 2 diabetes.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Platelets; Brachial Artery; Diabetes Mellitus, Type 2; Fasting; Female; Free Radicals; Humans; Lipid Peroxidation; Male; Middle Aged; Nitrates; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Oxidative Stress; Platelet Aggregation; Postprandial Period; Time Factors; Vasodilation | 2005 |
Vitamin E deficiency accelerates nitrate tolerance via a decrease in cardiac P450 expression and increased oxidative stress.
Topics: alpha-Tocopherol; Animals; Aorta; Cell Adhesion Molecules; Cyclic GMP; Cytochrome P-450 CYP1A2; Down-Regulation; Drug Tolerance; Lipid Peroxidation; Male; Microfilament Proteins; Myocardium; Nitrates; Nitric Oxide; Nitroglycerin; Oxidative Stress; Phosphoproteins; Phosphorylation; Rats; Reactive Oxygen Species; Serine; Vasodilator Agents; Vitamin E; Vitamin E Deficiency | 2006 |
Decreased nitrate-mediated dilatation in patients with coronary artery ectasia: an ultrasonographic evaluation of brachial artery.
Topics: Aged; Arm; Brachial Artery; Case-Control Studies; Coronary Artery Disease; Dilatation, Pathologic; Female; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Ultrasonography | 2006 |
Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2-/- mice.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Blotting, Western; Cell Adhesion Molecules; Cyclic GMP-Dependent Protein Kinases; Isometric Contraction; Luminescence; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Mitochondria, Muscle; Nitrates; Nitroglycerin; Nitroprusside; Oxadiazoles; Pentaerythritol Tetranitrate; Phosphoproteins; Quinoxalines; Structure-Activity Relationship; Vasodilator Agents | 2007 |
Effect of nitroglycerin on some parameters of the prooxidant-antioxidant balance and functional state of the liver during ischemia/reperfusion.
Topics: Alanine Transaminase; alpha-Tocopherol; Animals; Antioxidants; Aspartate Aminotransferases; Ischemia; Lipid Peroxidation; Liver; Male; Nitrates; Nitrites; Nitroglycerin; Rabbits; Reperfusion Injury; Schiff Bases | 2006 |
Determination of nitrate esters in water samples Comparison of efficiency of solid-phase extraction and solid-phase microextraction.
Topics: Adsorption; Calibration; Chromatography, High Pressure Liquid; Esters; Nitrates; Nitroglycerin; Reproducibility of Results; Solid Phase Microextraction; Solvents; Temperature; Time Factors; Water | 2007 |
The mechanism of nitrate-induced preconditioning.
Topics: Endothelium, Vascular; Equipment Design; Free Radicals; Humans; Ischemic Preconditioning; Mitochondria; Models, Biological; Nitrates; Nitric Oxide Donors; Nitro Compounds; Nitroglycerin; Permeability; Reactive Oxygen Species; Reperfusion Injury | 2008 |
Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate tolerance.
Topics: Animals; Arterioles; Cricetinae; Cysteine; Drug Tolerance; Enzyme Activation; Guanylate Cyclase; Mouth Mucosa; Nitrates; Nitroglycerin; Receptors, Cytoplasmic and Nuclear; S-Nitrosothiols; Soluble Guanylyl Cyclase; Vasodilation | 2008 |
Reduction of aliphatic nitroesters and N-nitramines by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase: quantitative structure-activity relationships.
Topics: Aniline Compounds; Azocines; Bacterial Proteins; Enterobacter cloacae; Kinetics; NADP; Nitrates; Nitro Compounds; Nitrobenzenes; Nitroglycerin; Oxidation-Reduction; Oxidoreductases; Substrate Specificity | 2008 |
Synthesis of some novel organic nitrates and comparative in vitro study of their vasodilator profile.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Aorta; Dose-Response Relationship, Drug; In Vitro Techniques; Mitochondrial Proteins; Nitrates; Nitroglycerin; Phenylephrine; Rats; Structure-Activity Relationship; Vasodilation; Vasodilator Agents | 2009 |
A new class of organic nitrates: investigations on bioactivation, tolerance and cross-tolerance phenomena.
Topics: Acetylcholine; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Drug Tolerance; Ethanolamines; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Nitrates; Nitroglycerin; Oxidative Stress; Vasodilation | 2009 |
Understanding organic nitrates--a vein hope?
Topics: Aldehyde Dehydrogenase; Angina Pectoris; Animals; Ascorbic Acid; Drug Tolerance; Mitochondria; Nitrates; Nitric Oxide; Nitroglycerin; Vasodilator Agents | 2009 |
Aminoethyl nitrate--the novel super nitrate?
Topics: Acetylcholine; Drug Tolerance; Guanylate Cyclase; Humans; Mitochondria; Nitrates; Nitroglycerin; Oxidative Stress; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation | 2009 |
Effects of Bi-NTO complex on thermal behaviors, nonisothermal reaction kinetics and burning rates of NG/TEGDN/NC propellant.
Topics: Bismuth; Calorimetry, Differential Scanning; Incineration; Kinetics; Nitrates; Nitro Compounds; Nitroglycerin; Temperature; Thermodynamics; Thermogravimetry; Triazoles | 2010 |
Nitroglycerin-induced preconditioning: interaction with nitrate tolerance.
Topics: Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Endothelium, Vascular; Heme Oxygenase-1; Humans; Ischemic Preconditioning; Nitrates; Nitroglycerin; Reperfusion Injury; Vasodilator Agents | 2010 |
Use of organic nitrates and the risk of hip fracture: a population-based case-control study.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Epidemiologic Methods; Female; Hip Fractures; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitrates; Nitroglycerin; Odds Ratio; Population; Risk; Vasodilator Agents; Young Adult | 2010 |
Drug action upon myocardial epinephreine-sympathin concentration and heart rate (nitro-glycerine, papverine, priscol, dibenamine hydrochloride).
Topics: Adrenal Glands; Catecholamines; Dibenzylchlorethamine; Ethylamines; Glycerol; Heart; Heart Rate; Humans; Imidazoles; Myocardium; Nitrates; Nitrites; Nitroglycerin; Papaverine; Tissue Extracts; Tolazoline | 1947 |
Nitrate-potentiated head-up tilt testing in older patients: outcomes, hemodynamic responses and prodrome recognition.
Topics: Adolescent; Adult; Aged; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Prevalence; Syncope, Vasovagal; Tilt-Table Test; Young Adult | 2010 |
Nitrate tolerance as a possible cause of multidrug-resistant coronary artery spasm.
Topics: Adult; Calcium Channel Blockers; Coronary Vasospasm; Drug Resistance, Multiple; Drug Tolerance; Humans; Male; Nitrates; Nitroglycerin; Vasodilator Agents | 2010 |
A novel class of nitrovasodilators: potency and in vitro tolerance of organic aminoalkylnitrates.
Topics: Animals; Dinoprost; Dose-Response Relationship, Drug; In Vitro Techniques; Nitrates; Nitroglycerin; Pulmonary Artery; Quaternary Ammonium Compounds; Structure-Activity Relationship; Swine; Tachyphylaxis; Vasodilation; Vasodilator Agents | 2010 |
Overestimation of nitrate and nitrite concentrations in water samples due to the presence of nitroglycerin or hexahydro-1,3,5-trinitro-1,3,5-triazine.
Topics: Chromatography, Ion Exchange; Colorimetry; Linear Models; Nitrates; Nitrites; Nitroglycerin; Solid Phase Extraction; Triazines; Water Pollutants, Chemical | 2012 |
[Reactive nitrogen and oxygen species metabolism in rat heart mitochondria upon administration of NO donor in vivo].
Topics: Animals; Calcium; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; Injections, Intraperitoneal; Iron; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroglycerin; Oxidation-Reduction; Oxidoreductases; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species | 2012 |
Vascular bioactivation of nitroglycerin by aldehyde dehydrogenase-2: reaction intermediates revealed by crystallography and mass spectrometry.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Amino Acid Substitution; Biocatalysis; Blood Vessels; Catalytic Domain; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Humans; Isoflavones; Mass Spectrometry; Models, Molecular; Molecular Structure; Mutant Proteins; Mutation; Nitrates; Nitroglycerin; Protein Binding; Protein Structure, Tertiary; Sulfur Compounds | 2012 |
Chronic nitrate therapy reduces positivity rate of tilt testing potentiated with sublingual nitroglycerin in patients with unexplained syncope.
Topics: Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Multivariate Analysis; Nitrates; Nitroglycerin; Predictive Value of Tests; Syncope; Tilt-Table Test; Vasodilator Agents | 2013 |
In vitro organic nitrate bioactivation to nitric oxide by recombinant aldehyde dehydrogenase 3A1.
Topics: Aldehyde Dehydrogenase; Animals; Aorta; Kinetics; Male; Mice; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitroglycerin; Recombinant Proteins | 2013 |
Aldehyde dehydrogenase 2 partly mediates hypotensive effect of nitrite on L-NAME-induced hypertension in normoxic rat.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrazines; Hypertension; Male; Mitochondrial Proteins; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Time Factors | 2014 |
Nitroglycerine-induced nitrate tolerance compromises propofol protection of the endothelial cells against TNF-α: the role of PKC-β2 and NADPH oxidase.
Topics: Apoptosis; Cell Survival; Cytoprotection; Flow Cytometry; Human Umbilical Vein Endothelial Cells; Humans; L-Lactate Dehydrogenase; Malondialdehyde; NADPH Oxidases; Nitrates; Nitrites; Nitroglycerin; Phthalimides; Propofol; Protein Kinase C beta; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine | 2013 |
Cardiorespiratory effects induced by 2-nitrate-1,3-dibuthoxypropan are reduced by nitric oxide scavenger in rats.
Topics: Animals; Arterial Pressure; Bradycardia; Cardiovascular Agents; Consciousness; Dose-Response Relationship, Drug; Heart Rate; Hydroxocobalamin; Hypotension; Male; Nitrates; Nitric Oxide; Nitroglycerin; Propane; Rats; Rats, Wistar; Respiration; Tachypnea; Vasodilator Agents | 2014 |
Near infrared spectral imaging for the analysis of dynamite residues on human handprints.
Topics: Adult; Diagnostic Imaging; Discriminant Analysis; Explosive Agents; Female; Hand; Humans; Least-Squares Analysis; Male; Nitrates; Nitroglycerin; Spectroscopy, Near-Infrared; Young Adult | 2014 |
The effect of peroxynitrite decomposition catalyst MnTBAP on aldehyde dehydrogenase-2 nitration by organic nitrates: role in nitrate tolerance.
Topics: Aldehyde Dehydrogenase; Animals; Aorta; Blood Platelets; Cyclic GMP; Drug Tolerance; Endothelium, Vascular; Humans; Hypotension; Isosorbide Dinitrate; Male; Metalloporphyrins; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Platelet Aggregation; Rats; Thrombin; Tyrosine; Vasodilator Agents | 2014 |
Prognostic impact of chronic nitrate therapy in patients with vasospastic angina: multicentre registry study of the Japanese coronary spasm association.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Coronary Vasospasm; Female; Humans; Isosorbide; Male; Nicorandil; Nitrates; Nitroglycerin; Prognosis; Prospective Studies; Registries; Retrospective Studies | 2015 |
Vasorelaxing effects of the soluble guanylyl cyclase activator BAY 60-2770 in nitrate-tolerant monkey and canine coronary arteries.
Topics: Animals; Benzoates; Biphenyl Compounds; Coronary Vessels; Dogs; Female; Guanylate Cyclase; Hydrocarbons, Fluorinated; In Vitro Techniques; Macaca fascicularis; Male; Nitrates; Nitroglycerin; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilator Agents | 2015 |
Influence of Intravenous Nitrate Treatment on Early Mortality Among Patients With Acute Heart Failure. NITRO-EAHFE Study.
Topics: Aged; Aged, 80 and over; Cohort Studies; Emergency Service, Hospital; Female; Heart Failure; Humans; Infusions, Intravenous; Male; Nitrates; Nitroglycerin; Prognosis; Proportional Hazards Models; Prospective Studies; Vasodilator Agents | 2015 |
Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats.
Topics: Animals; Aorta; Benzoates; Biphenyl Compounds; Enzyme Activation; Guanylate Cyclase; Hydrocarbons, Fluorinated; Male; Morpholines; Nitrates; Nitroglycerin; Organ Culture Techniques; Oxidative Stress; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2015 |
Effects of nitric oxide on blood-brain barrier permeability in common carp (Cyprinus carpio L.).
Topics: Animals; Blood-Brain Barrier; Brain Edema; Carps; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Permeability; Vasodilator Agents | 2015 |
Stable isotope-assisted LC-MS/MS monitoring of glyceryl trinitrate bioactivation in a cell culture model of nitrate tolerance.
Topics: Cell Line; Chromatography, Liquid; Endothelial Cells; Humans; Isotope Labeling; Nitrates; Nitrites; Nitrogen Isotopes; Nitroglycerin; Tandem Mass Spectrometry | 2016 |
The Effect Of NO Donor on Calcium Uptake and Reactive Nitrogen Species Production in Mitochondria.
Topics: Animals; Biological Transport; Calcium; Citrulline; Dose-Response Relationship, Drug; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroglycerin; Rats, Wistar; Reactive Nitrogen Species; S-Nitrosothiols | 2016 |
Progressing the analysis of Improvised Explosive Devices: Comparative study for trace detection of explosive residues in handprints by Raman spectroscopy and liquid chromatography.
Topics: Chromatography, Liquid; Explosive Agents; Female; Hand; Humans; Male; Nitrates; Nitroglycerin; Powders; Spectrum Analysis, Raman | 2016 |
A Case of Acute Myocardial Infarction Induced by Selective Cyclooxygenase-2 Inhibitor.
Topics: Calcium Channel Blockers; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Male; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Orphenadrine | 2017 |
Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance.
Topics: Aldehyde Dehydrogenase, Mitochondrial; Animals; Aorta, Thoracic; Cell Line, Transformed; Cell Line, Tumor; Dithiothreitol; Drug Tolerance; Female; Humans; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Organ Culture Techniques; Rats; Rats, Sprague-Dawley | 2018 |
S-Nitrosylation of Prostacyclin Synthase Instigates Nitrate Cross-Tolerance In Vivo.
Topics: Aged; Aged, 80 and over; Amino Acid Sequence; Animals; Cattle; Cricetinae; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Tolerance; Female; Human Umbilical Vein Endothelial Cells; Humans; Intramolecular Oxidoreductases; Male; Mice; Mice, Knockout; Middle Aged; Nitrates; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2019 |
Liquid Chromatographic Method Development for Quantification of Inorganic Nitrite and Nitrate Impurities from Nitroglycerin Drug Substance by Using Ion-Pair Reagents with Liquid-Liquid Extraction Technique.
Topics: Chromatography, Liquid; Hydrogen-Ion Concentration; Liquid-Liquid Extraction; Nitrates; Nitrites; Nitroglycerin | 2019 |
Nitrates administered by spray versus tablet: comparison of coronary vasodilation on CT angiography.
Topics: Administration, Sublingual; Aged; Computed Tomography Angiography; Coronary Angiography; Coronary Vessels; Humans; Nitrates; Nitroglycerin; Retrospective Studies; Tablets; Vasodilation | 2021 |
Biotransformation of organic nitrates by glutathione S-transferases and other enzymes: An appraisal of the pioneering work by William B. Jakoby.
Topics: Biotransformation; Glutathione; Glutathione Disulfide; Nitrates; Nitrites; Nitroglycerin; Transferases | 2022 |
S-Nitrosylation of Akt by organic nitrate delays revascularization and the recovery of cardiac function in mice following myocardial infarction.
Topics: Adenoviridae; Amino Acid Sequence; Animals; Apolipoproteins E; Cell Movement; Cell Proliferation; Cysteine; HEK293 Cells; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mutation; Myocardial Infarction; Myocardial Revascularization; Neovascularization, Physiologic; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Nitrosation; Proto-Oncogene Proteins c-akt | 2021 |
Vascular biotransformation of organic nitrates is independent of cytochrome P450 monooxygenases.
Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; Mice; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate | 2021 |
Sublingual Nitrates for Patients as a Default in the Post-ACS Discharge Pack: Is It Time for a Rethink?
Topics: Administration, Sublingual; Humans; Nitrates; Nitroglycerin; Patient Discharge; Vasodilator Agents | 2022 |
Endocrine disruption: Reproductive toxicity of glyceryl trinitrate and isosorbide mononitrate in male Wistar rats.
Topics: Animals; Isosorbide Dinitrate; Luteinizing Hormone; Male; Nitrates; Nitric Oxide; Nitroglycerin; Oxidative Stress; Rats; Rats, Wistar; Semen; Sperm Count; Sperm Motility; Spermatozoa; Testis; Testosterone | 2022 |
Synthesis and Vasorelaxant Activity of Nitrate-Coumarin Derivatives.
Topics: Animals; Coumarins; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Rats; Vasodilator Agents | 2022 |