nitrates has been researched along with cyclic gmp in 367 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (5.45) | 18.7374 |
| 1990's | 132 (35.97) | 18.2507 |
| 2000's | 163 (44.41) | 29.6817 |
| 2010's | 47 (12.81) | 24.3611 |
| 2020's | 5 (1.36) | 2.80 |
| Authors | Studies |
|---|---|
| Craven, P; DeRubertis, FR | 1 |
| Charles, JM; Menzel, DB | 1 |
| Schröder, H | 1 |
| Fung, HL; Tzeng, TB | 1 |
| Eguchi, S; Emori, T; Hirata, Y; Imai, T; Kanno, K; Marumo, F; Ohta, K | 2 |
| Bennett, BM; Long, PG; McDonald, BJ; Nigam, R; Simon, WC | 1 |
| Billiar, TR; Di Silvio, M; Geller, DA; Hoffman, RA; Madariaga, J; Nussler, AK; Selby, R; Simmons, RL | 1 |
| Agulló, L; García, A | 1 |
| Cantor, E; Greenberg, SS; Ho, E; Walega, M | 1 |
| Förster, S; Schröder, H; Schrör, K; Woditsch, I | 1 |
| Marletta, MA; Raij, L; Shultz, PJ; Tayeh, MA | 1 |
| Ballermann, BJ; Marsden, PA | 1 |
| Fasehun, OA; Griffith, OW; Gross, SS; Jaffe, EA; Levi, R; Rubin, LE | 1 |
| Taira, N | 1 |
| Drummer, C; Gerzer, R; Heim, JM; Karrenbrock, B | 1 |
| Ahlner, J; Axelsson, KL; Torfgård, K | 1 |
| Chong, S; Chung, SJ; Fung, HL; Hough, K; Kakami, M; Kowaluk, E | 1 |
| Hashimoto, H; Ito, T; Nakagawa, H; Ogawa, K; Okumura, K; Satake, T | 1 |
| Holzmann, S; Kukovetz, WR | 4 |
| Holzmann, S; Kukovetz, WR; Romanin, C | 1 |
| Bennett, BM; Hayward, LD; Murad, F; Schröder, H; Waldman, SA | 1 |
| Bertel, O | 1 |
| Bassenge, E; Busse, R; Mülsch, A | 1 |
| Hofmann, F; Kreye, VA; Villhauer, I | 1 |
| Ahlner, J; Axelsson, KL | 2 |
| Osnes, JB | 1 |
| Kobayashi, A; Ogawa, K; Yamazaki, N | 1 |
| Chen, PY; Sanders, PW | 1 |
| Adachi, H; Esumi, H; Kato, R; Marumo, T; Miyata, M; Nagata, K; Nakaki, T; Saruta, T; Suzuki, H | 1 |
| Bockaert, J; Culcasi, M; Gaven, F; Lafon-Cazal, M; Pietri, S | 1 |
| Inoue, M; Kida, T; Kobayashi, K; Kuroki, T | 1 |
| Absood, A; Berisha, HI; Pakbaz, H; Said, SI | 1 |
| Raij, L; Shultz, PJ; Tolins, JP; Westberg, G | 1 |
| Dawson, TM; Dawson, V; Dinerman, JL; Snyder, SH; Steiner, JP | 1 |
| Bartoli, F; Billiar, TR; Di Silvio, M; Dorko, K; Freeswick, P; Geller, DA; Liu, ZZ; Nussler, AK | 1 |
| Deliconstantinos, G; Stavrides, JC; Villiotou, V | 2 |
| Archer, SL; Freude, KA; Shultz, PJ | 1 |
| Bosia, A; Bussolino, F; Costamagna, C; Deharo, E; Gabrielli, G; Gautret, P; Ghigo, D; Ginsburg, H; Giribaldi, G; Pescarmona, G; Todde, R; Ulliers, D | 1 |
| Bode-Böger, SM; Böger, RH; Frölich, JC; Schröder, EP | 1 |
| Klatt, P; Koesling, D; Mayer, B; Schmidt, K; Schrammel, A | 1 |
| Conrad, KP; McLaughlin, MK | 1 |
| Chavez, JE; Conrad, KP; Joffe, GM; Kruszyna, H; Kruszyna, R; Mosher, MD; Rochelle, LG; Smith, RP | 1 |
| Currie, MG; Masferrer, JL; Misko, TP; Needleman, P; Salvemini, D; Seibert, K | 1 |
| Kojda, G; Noack, E | 1 |
| Lu, X; Wei, HM; Weiss, HR; Yospin, J | 1 |
| Czarnecka, D; Dembinska-Kiec, A; Goldsztajn, P; Kawecka-Jaszcz, K; Malczewska-Malec, M; Siedlecki, A; Siemienska, T | 1 |
| Beckman, JS; Brock, TA; Gore, JZ; Ischiropoulos, H; Tarpey, MM | 1 |
| Horio, T; Kano, H; Kohno, M; Mandel, AK; Mankus, R; Minami, M; Saklayen, MG; Takeda, T; Yasunari, K; Yokokawa, K | 1 |
| Takahashi, H; Wakabayashi, Y; Yamada, E; Yoshida, T | 1 |
| Bode-Böger, SM; Böger, RH; Frölich, JC; Gutzki, FM; Selve, N; Stichtenoth, DO; Tsikas, D | 1 |
| Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Gutzki, FM; Tsikas, D | 1 |
| Arias-Díaz, J; Baki, W; Balibrea, JL; García, C; Ramírez-Armengol, JA; Torres-Melero, J; Vara, E | 1 |
| Blum, M; Cabili, S; Grosskopf, I; Iaina, A; Levo, Y; Maree, A; Peer, G; Schwartz, D; Serban, I; Wollman, Y | 1 |
| Frangos, JA; Kuchan, MJ | 1 |
| Bode-Böger, SM; Böger, RH; Frölich, JC; Gerecke, U | 1 |
| Bécherel, PA; Chosidow, O; Dugas, B; Frances, C; Guillosson, JJ; Kilchherr, E; Le Goff, L; Mossalayi, MD; Ouaaz, F; Paul-Eugène, N | 1 |
| Schrör, K; Strobach, H; Weber, AA | 1 |
| Miyata, N; Otomo, S; Takahashi, K; Tanaka, M; Tsuchida, K; Yamaura, H | 1 |
| Grider, JR; Jin, JG; Makhlouf, GM; Murthy, KS | 1 |
| Curtis, MJ; Garlick, PB; Ridley, PD | 1 |
| Kinoshita, M; Matsumoto, T; Okamura, T; Toda, N | 1 |
| Brands, F; Feelisch, M; Kelm, M | 1 |
| Ikeda, M; Matsunaga, T; Murota, S; Sato, I; Takahashi, M; Yuasa, T | 1 |
| Antonello, A; Bordin, MC; Borsatti, A; Caló, L; Cantaro, S; D'Angelo, A; Favaro, S | 1 |
| Aihara, T; Ikeda, Y; Koyama, Y; Kusano, T; Muto, Y; Shiraishi, M | 1 |
| Brixius, K; Kojda, G; Kottenberg, K; Nix, P; Noack, E; Piper, HM; Schlüter, KD | 1 |
| Han, SW; Kim, H | 1 |
| Ikeda, M; Miyatake, T; Murota, S; Sato, I; Yuasa, T | 1 |
| Lai, PS; Rodriguez, A; Spur, BW; Wong, PY; Yin, K | 1 |
| Boegehold, MA; Dubey, RK; Gillespie, DG; Rosselli, M | 1 |
| Chou, SM; Komai, K; Wang, HS | 1 |
| Clark, DA; Eloby-Childress, S; Liu, X; Miller, MJ; Sadowska-Krowicka, H; Thompson, JH; Zhang, XJ | 1 |
| Corell, T; Holm, P; Kankaanranta, H; Karup, G; Metsä-Ketelä, T; Moilanen, E; Pedersen, SB; Petersson, AS; Rydell, E; Vuorinen, P; Wennmalm, A | 1 |
| Cremonesi, P; Donà, G; Giuliani, P; Mizrahi, J; Passaro, A; Stella, P; Tursi, F | 1 |
| Arima, T; Kitamura, Y; Mizuno, T; Nomura, Y; Ohshima, Y; Segawa, T | 1 |
| Capasso, F; Izzo, AA; Maiolino, P; Mascolo, N | 1 |
| Kikawada, R; Wakabayashi, Y | 1 |
| Agapito, MT; Guerrero, JM; Ortiz, GG; Pablos, MI; Reiter, RJ | 1 |
| Bode-Böger, SM; Böger, RH; Brabant, G; Frolich, JC; Skamira, C; von zur Muhlen, A | 1 |
| Nanbu, A; Nishimura, M; Ohtsuka, K; Takahashi, H; Yoshimura, M | 1 |
| Hemmens, B; Leopold, E; Mayer, B; Pfeiffer, S; Schmidt, K; Werner, ER | 1 |
| Buunk, G; Frölich, M; Meinders, AE; van der Hoeven, JG | 1 |
| Arakawa, T; Fujiwara, Y; Fukuda, T; Higuchi, K; Inoue, M; Kobayashi, K; Uno, H; Yu, H | 1 |
| Alexander, K; Bode-Böger, SM; Böger, RH; Frölich, JC; Junker, W; Thiele, W | 1 |
| Holm, P; Kankaanranta, H; Knowles, RG; Kosonen, O; Moilanen, E; Vuorinen, P | 1 |
| Garver, RI; Haddad, IY; Hong, J; Matalon, S; Sorscher, EJ; Tzeng, E | 1 |
| Bosson, C; Bruniaux, J; Demontoux, S; Détruit, H; Duchateau, J; Lecronier, G; Mokhfi, E; Planché, C; Seghaye, MC; Serraf, A | 1 |
| Morcos, S; Ni, Z; Vaziri, ND | 1 |
| Blantz, RC; Mendonca, M; Satriano, J; Schwartz, D; Schwartz, I; Wilson, CB; Xia, Y | 1 |
| Higa, T; Hiroyasu, S; Kusano, T; Miyaguni, T; Muto, Y; Nagahama, M; Okuhama, Y; Shiraishi, M; Tomori, H | 1 |
| Bode-Böger, SM; Böger, RH; Böhme, M; Brandes, RP; Frölich, JC; Mügge, A; Nafe, R; Phivthong-ngam, L | 1 |
| Kang, KW; Kim, ND; Kim, SG; Schini-Kerth, VB | 1 |
| Foster, HE; Saito, N; Smith, SD; Weiss, RM; Wheeler, MA | 1 |
| Aversa, K; Copel, JA; Hsu, CD; Lee, IS; Meaddough, E | 1 |
| Abraham, WT; Chapman, AB; Coffin, C; Dahms, T; Johnson, A; Merouani, A; Moore, LG; Osorio, F; Schrier, RW; Woodmansee, W; Zamudio, S | 1 |
| Chen, HI; Jen, CJ; Wang, JS | 1 |
| Bondy, SC; Ding, Y; Gonick, HC; Ni, Z; Vaziri, ND | 1 |
| Asanuma, H; Funaya, H; Hori, M; Kitakaze, M; Koretsune, Y; Minamino, T; Sato, H | 1 |
| Hattori, K; Komatsu, T; Nabeshima, T; Nagata, M; Nishiwaki, K; Senzaki, K; Shimada, Y; Yamada, K | 1 |
| Kinoshita, M; Liu, Q; Matsumoto, T; Mitsunami, K; Nakae, I; Takahashi, M; Takaoka, A | 1 |
| De Koster, BM; Elferink, JG; Van Der Zee, J; Vansteveninck, J; Vanuffelen, BE | 1 |
| Burstyn, JN; Dierks, EA | 1 |
| Brandi, ML; MacIntyre, I; Mancini, L; Moradi-Bidhendi, N | 1 |
| de Waart, DR; Douma, CE; Hiralall, JK; Krediet, RT; Struijk, DG | 1 |
| Kaminski, PM; Wolin, MS; Xie, YW | 1 |
| Hara, K; Maruyama, K; Nanbu, A; Nishimura, M; Ohtsuka, K; Takahashi, H; Yoshimura, M | 1 |
| Kakihana, M; Ohtsuka, S; Sugishita, Y; Watanabe, H | 2 |
| Hinz, B; Schröder, H | 1 |
| Fukuyama, N; Nakazawa, H; Sakai, M; Sato, M | 1 |
| Lu, M; Wang, WH | 1 |
| Bassenge, E; Dikalov, S; Fink, B; Skatchkov, M; Stalleicken, D | 1 |
| Leza, JC; Radomski, MW; Russell, JC; Salas, E; Sawicki, G | 1 |
| Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Thiele, W | 1 |
| Carlström, K; Grunewald, C; Kumlien, G; Lundberg, J; Ringqvist, A | 1 |
| Keiser, HR; Oriji, GK | 1 |
| Bode-Böger, SM; Böger, RH; Frölich, JC; Galland, A; Tsikas, D | 1 |
| Butler, R; Leone, A; Morris, AD; Struthers, AD | 1 |
| Hirata, Y; Kakoki, M; Matsumoto, A; Momomura, Si; Nagata, D; Omata, M; Sugimoto, T; Tagawa, H | 1 |
| Inada, H; Onaya, T; Shindo, H; Tawata, M | 1 |
| Baker, JE; Holman, P; Kalyanaraman, B; Pritchard, KA | 1 |
| Brown, AS; Cramer, EM; Darley-Usmar, V; Masse, JM; Moro, MA; Radomski, M | 1 |
| Eriksson, A; Fyhrquist, F; Holthöfer, H; Miettinen, A; Tikkanen, I; Tikkanen, T; Törnroth, T; Uhlenius, N | 1 |
| Cahill, PA; Hannan, RL; Kim, YD; Kouretas, PC; Myers, AK; Sitzmann, JV; To, LN; Wang, YN | 1 |
| Atarashi, K; Goto, A; Hirata, Y; Ishiyama, A; Minami, M; Omata, M | 1 |
| Fuller, BJ; Moorhead, JF; Rahman, MM; Varghese, Z | 1 |
| Brand, R; Egberts, J; van den Bosch, N | 1 |
| Albrecht, R; Folts, JD; Loscalzo, J; Maalej, N | 1 |
| Blasig, IE; Haseloff, RF; Mertsch, K; Paul, M; Ruth, P; Schönfelder, G; Smolenski, A; Sporbert, A; Walter, U | 1 |
| Baylis, C; Schmidt, RJ; Sorkin, MI; Tracy, TS; Yokota, S | 1 |
| Banks, SM; Danner, RL; Eidsath, A; Godin, PJ; Leighton, SB; Preas, HL; Suffredini, AF; Vandivier, RW | 1 |
| Ikawa, S; Kono, S; Kotani, K; Murakami, F; Shimomura, T | 1 |
| Panesar, NS | 1 |
| Holm, P; Kankaanranta, H; Knowles, RG; Moilanen, E; Oja, SS | 1 |
| Baker, JE; Griffith, OW; Holman, P; Kalyanaraman, B; Pritchard, KA | 1 |
| Baylis, C; Domico, J; Engels, K; Samsell, LS; Schmidt, RJ; Sorkin, MI; Tracy, TS; Yokota, S | 1 |
| Andreucci, M; Andreucci, VE; Bellizzi, V; Capuano, A; Cianciaruso, B; Corso, G; De Nicola, L; Garibotto, G; Minutolo, R | 1 |
| Bär, PR; Joosten, EA; Kaal, EC; Kil, AC; Sodaar, P | 1 |
| Muramatsu, I; Takakura, K | 1 |
| Hatsuoka, S; Mayer, JE; Nagashima, M; Nollert, G; Shum-Tim, D; Sperling, J; Stock, U | 1 |
| Ambalavanan, N; Bulger, A; Mariani, G; Philips III, JB | 1 |
| Davies, GJ; Tousoulis, D; Toutouzas, PC | 1 |
| Chou, TC; Ding, YA; Li, CY; Yen, MH | 1 |
| Chesnais, JM; Fischmeister, R; Mery, PF | 1 |
| Toda, N | 1 |
| Costa, S; Monti, LD; Phan, CV; Piatti, PM; Pontiroli, AE; Pozza, G; Sandoli, EP; Valsecchi, G | 1 |
| de Sena Bernardes, C; Demarchi Munhoz, C; Glezer, I; Pekelmann Markus, R; Scavone, C | 1 |
| Hong, KW; Shin, HK; Shin, YW | 1 |
| Akita, H; Hirata, K; Inoue, N; Ishida, T; Kawashima, S; Ohashi, Y; Ozaki, M; Ueyama, T; Yamashita, T; Yokoyama, M | 1 |
| Chao, J; Chao, L; Song, Q; Wang, D; Yoshida, H | 1 |
| Asai, Y; Esaki, T; Hayashi, T; Iguchi, A; Jayachandran, M; Kano, H; Muto, E; Sumi, D; Thakur, NK | 2 |
| Bit-Avragim, N; Bode-Böger, SM; Böger, RH; Dietz, R; Ellmer, AE; Hänlein, D; Osterziel, KJ; Ranke, MB; Strohm, O | 1 |
| Bode-Böger, SM; Böger, RH; Frölich, JC; Kielstein, JT; Löffler, M; Schäffer, J | 1 |
| Eidelman, D; Govindaraju, K; Nagi, M; Thibault, G; Toporsian, M; Ward, ME | 1 |
| Bode-Böger, SM; Böger, RH; Cooke, JP; Imaizumi, T; Matsuoka, H; Miyazaki, H; Okuda, S; Ueda, S; Usui, M | 1 |
| Lee, SS; Liu, H; Ma, Z | 1 |
| Andersen, GN; Caidahl, K; Kazzam, E; Mincheva-Nilsson, L; Petersson, AS; Rantapää-Dahlqvist, S; Waldenström, A | 1 |
| Chen, Q; Gole, M; Gow, AJ; Ischiropoulos, H; Lee, VM; Themistocleous, M | 1 |
| Hon, WM; Lee, JC; Lee, KH | 1 |
| Asoh, K; Kobayashi, S; Koitabashi, Y; Kumai, T; Murano, K | 1 |
| Agata, J; Chao, J; Chao, L; Wolf, WC; Yoshida, H | 1 |
| Lorber, MI; Smith, SD; Weiss, RM; Wheeler, MA | 1 |
| Chang, W; Hsiao, G; Lee, C; Lee, LW; Lin, CH; Sheu, JR; Su, CH | 1 |
| Bing, RJ; Grubbs, RH; Kim, H; Yamamoto, T | 1 |
| Kendrick, KM; Trabace, L | 1 |
| Ekelund, UE; Georgakopoulos, D; Hare, JM; Harrison, RW; Isoda, T; Kass, DA; Ozaki, M; Paolocci, N; Vandegaer, K | 1 |
| Duszyk, M; Kamosinska, B; Man, SF; Radomski, A; Radomski, MW | 1 |
| Croatt, AJ; Haggard, JJ; Hebbel, RP; Katusic, ZS; Nath, KA; Shah, V; Smith, LA | 1 |
| Bekker, JM; Black, SM; Fineman, JR; Heidersbach, RS; Johengen, MJ; Kon, A; McMullan, DM; Parry, AJ | 1 |
| Duan, J; Ikeda, H; Imaizumi, T; Katoh, A; Kawata, H; Murohara, T; Sasaki, K; Shintani, S; Yamamoto, N | 1 |
| Caidahl, K; Petersson, AS; Ringqvist, A; Wennmalm, A | 1 |
| Antonetti, DA; Gardner, TW; Lakshminarayanan, S; Tarbell, JM | 1 |
| Akita, T; Duan, J; Ikeda, H; Imaizumi, T; Murohara, T; Sasaki, K; Shimada, T; Shintani, S | 1 |
| Moorhead, JF; Rahman, MM; Varghese, Z | 1 |
| Blantz, RC; Schwartz, D; Schwartz, IF | 1 |
| Fraser, T; Li, M; Turner, SW; Wang, J; Wen, C; Whitworth, JA | 1 |
| Antonio, MT; Bragulat, E; Coca, A; de la Sierra, A | 1 |
| Giardina, JB; Granger, JP; Green, GM; Khalil, RA; Rinewalt, AN | 1 |
| Aydin, A; Işimer, A; Orhan, H; Ozata, M; Sahin, G; Sayal, A | 1 |
| Gabbai, FB; Henry, RR; Kailasam, MT; Martinez, JA; Miller, LM; O'Connor, DT; Parmer, RJ; Tyrell, EA | 1 |
| Kinoshita, M; Matsumoto, T; Nakae, I; Omura, T; Takahashi, M | 1 |
| Garrard, CS; MacKenzie, IM; Young, JD | 1 |
| Abe, Y; Chen, QH; Kosaka, H; Tian, RX; Yamamoto, A; Yoneyama, H; Zhang, L; Zhou, MS | 1 |
| Osinski, MT; Rauch, BH; Schrör, K | 1 |
| Bird, IM; Li, Y; Magness, RR; Shaw, CE; Sheppard, C | 1 |
| Huang, Q; Huang, X; Jin, C; Liu, J; Yang, GY; Zhao, KS | 1 |
| Baylis, C; Beierwaltes, WH; Schmidt, RJ | 1 |
| Bindels, AJ; Frölich, M; Groeneveld, PH; Meinders, AE; van der Hoeven, JG | 1 |
| Bonfante, L; Calò, L; Cantaro, S; D'Angelo, A; Marcon, R; Masiero, M; Milan Manani, S | 1 |
| Heck, DE | 1 |
| Antonio, MT; Bragulat, E; Coca, A; de la Sierra, A; Jiménez, W | 1 |
| Egashira, K; Hayashi, T; Iguchi, A; Kano, H; Matsui-Hirai, H; Sumi, D; Thakur, NK; Tsunekawa, T | 1 |
| Edelstein, C; Gengaro, P; Lelamali, K; Schrier, RW; Wang, W | 1 |
| Espey, MG; Feelisch, M; Fukuto, JM; Hare, JM; Isoda, T; Kass, DA; Martignani, C; Miranda, KM; Paolocci, N; Saavedra, WF; Wink, DA | 1 |
| Eto, S; Hashimoto, O; Ikeda, M; Inada, Y; Ito, A; Kaizu, K; Qie, YL; Suzuka, K; Takagi, I; Tanaka, Y; Uriu, K | 1 |
| Bettendorf, M; Fiehn, W; Gorenflo, M; Pöge, A; Ulmer, HE; Werle, E; Zheng, C | 1 |
| Galiñanes, M; Matata, BM | 1 |
| Goto, T; Hosogai, N; Seki, J | 1 |
| Cohen, RA; Shi, C; Zou, MH | 1 |
| Abe, Y; Fukui, T; Kimura, S; Kosaka, H; Nishiyama, A; Rahman, M; Yoneyama, H | 2 |
| Antunes-Rodrigues, J; Branco, LG; McCann, SM; Steiner, AA | 1 |
| Fung, HL; Lee, WI; Wang, EQ | 1 |
| Bruckdorfer, KR; Low, SY; Naseem, KM; Sabetkar, M | 1 |
| Abe, Y; Fujisawa, Y; Kimura, S; Kondou, N; Kosaka, H; Nishiyama, A; Rahman, M; Tian, RX; Yoneyama, H; Zhou, MS | 1 |
| Himeno, M; Ishibashi, T; Maejima, K; Nakano, S; Nishio, M; Uchida, K | 1 |
| Aine, E; Kotikoski, H; Moilanen, E; Vapaatalo, H | 1 |
| Hillsley, MV; Tarbell, JM | 1 |
| Akimoto, T; Amemiya, M; Asano, Y; Iimura, O; Inoue, M; Ito, C; Kusano, E; Muto, S; Nemoto, J | 1 |
| Devine, AB; Dixon, LJ; Hamilton, P; Hanratty, CG; Leahey, WJ; McGrath, LT; McVeigh, GE; Morgan, DG; Wilson, M | 1 |
| Andersen, GN; Caidahl, K; Kazzam, E; Klintland, N; Mincheva-Nilsson, L; Nyberg, G; Petersson, AS; Rantapää-Dahlqvist, S; Waldenström, A | 1 |
| Morbidelli, L; Ziche, M | 1 |
| Benjamin, N; Frost, MT; Hicks, SL; McKnight, GM; Moore, K; O'Byrne, S; Richardson, G | 1 |
| Beltowski, J; Borkowska, E; Wójcicka, G | 1 |
| Hur, TY; Kang, DG; Kwon, TO; Lee, GM; Lee, HS; Oh, H; Sohn, EJ | 1 |
| Bennett, BM; Boegman, RJ; Dumitrascu, A; Jhamandas, K; Ratz, JD; Reynolds, JN; Scutaru, D; Thatcher, GR; Zavorin, SI | 1 |
| Billiar, TR; Ha, KS; Hatakeyama, K; Kim, CK; Kim, PK; Kim, YM; Kwon, YG; Lee, KS; Lee, SJ; Na, HJ; Park, JH; Yoneyama, T | 1 |
| Egberts, J; Hempenius, I; Krediet, TG; Valk, L; van Bel, F | 1 |
| Kankuri, E; Kotikoski, H; Vapaatalo, H | 1 |
| Hasuike, Y; Hiraoka, K; Inoue, T; Itahana, R; Izumi, M; Miyagawa, K; Nakanishi, T; Nishihara, F; Takamitsu, Y | 1 |
| Chiang, CE; Ding, PY; Luk, HN; Sheu, JR; Wang, TM | 1 |
| Myers, J; Nolan, BP; Senechal, P; Standley, CA; Standley, PR; Waqar, S | 1 |
| Albert, J; Lundberg, JO; Palm, J; Sollevi, A; Soop, A; Weitzberg, E | 1 |
| Abadir, PM; Carey, RM; Siragy, HM | 1 |
| Berti, F; Del Soldato, P; Manfredi, B; Polvani, G; Rossoni, G | 1 |
| Dong, Y; Gerzanich, V; Ivanov, A; Ivanova, S; Simard, JM; Yang, JB; Zhou, H | 1 |
| Amado, JA; Bustamante, M; de Berrazueta, JR; Garcia-Unzueta, MT; Llorca, J; Sampedro, I | 1 |
| Batinic-Haberle, I; Christopher, TA; Gao, E; Liu, HR; Lopez, BL; Ma, XL; Ohlstein, EH; Tao, L; Teng, ZP; Willette, RN; Yue, TL | 1 |
| Feil, R; Hofmann, F | 1 |
| Hao, JX; Impagnatiello, F; Ongini, E; Presotto, C; Wiesenfeld-Hallin, Z; Wu, WP; Xu, XJ | 1 |
| Lau, YT; Yen, CH | 1 |
| Anim-Nyame, N; Gamble, J; Johnson, MR; Sooranna, SR; Steer, PJ | 1 |
| Cittadino, M; Moreno, H; Sabha, M; Sousa, MG; Tácito, LH; Tanus-Santos, JE; Yugar-Toledo, JC | 1 |
| Chang, Y; Chou, DS; Hsiao, G; Lee, LW; Lin, CH; Shen, MY; Sheu, JR | 1 |
| Bojunga, J; Dresar-Mayert, B; Kusterer, K; Usadel, KH; Zeuzem, S | 1 |
| Cianchi, F; Cortesini, C; Di Felice, A; Fabbroni, V; Fantappiè, O; Lasagna, N; Masini, E; Mazzanti, R; Messerini, L; Perigli, G; Perna, F; Sardi, I | 1 |
| Cachofeiro, V; Fernández-Alfonso, MS; González, C; Lahera, V; Somoza, B | 1 |
| Azakie, A; Black, SM; Fineman, JR; Fitzgerald, R; Fratz, S; Hess, J; Johengen, MJ; Meyrick, B; Oishi, P; Ovadia, B; Reinhartz, O; Ross, G | 1 |
| Bełtowski, J; Jochem, J; Wójcicka, G; Zwirska-Korczala, K | 1 |
| Falcinelli, F; Floridi, A; Gresele, P; Imperiali, P; Migliacci, R; Nenci, GG | 1 |
| Chang, Y; Chen, TL; Fong, TH; Hsiao, G; Liu, CM; Lu, MS; Shen, MY; Sheu, JR | 1 |
| Calò, LA; Ceolotto, G; Davis, PA; Pagnin, E; Pessina, AC; Sartori, M; Semplicini, A | 1 |
| Egami, K; Ikeda, H; Imaizumi, T; Katsuda, Y; Murohara, T; Nabeshima, Y; Sasaki, K; Shimada, T; Shintani, S; Takeshita, Y | 1 |
| Bennett, BM; Nicolescu, AC; Thatcher, GR; Toader, V | 1 |
| Benigni, A; Corna, D; Longaretti, L; Maggioni, P; Noris, M; Remuzzi, G; Rottoli, D; Todeschini, M; Zatelli, C; Zoja, C | 1 |
| Chen, TF; Chou, DS; Fong, TH; Hsiao, G; Lin, CH; Shen, MY; Sheu, JR | 1 |
| Croatt, AJ; Katusic, ZS; Lam, CF; Nath, KA; Richardson, DM | 1 |
| Connelly, L; Hobbs, AJ; Madhani, M | 1 |
| Chen, KH; Chen, SJ; Wu, CC | 1 |
| de Groot, H; Dejam, A; Gharini, P; Horstjann, M; Kelm, M; Kirsch, M; Kolb-Bachofen, V; Mürtz, M; Paunel, AN; Suschek, CV; Thelen, S | 1 |
| Bosia, A; Costamagna, C; Ghigo, D; Miraglia, E; Pescarmona, G; Riganti, C; Viarisio, D | 1 |
| Huang, CF; Lau, YT; Wang, YR; Yen, CH | 1 |
| Bonartsev, AP; D'iakonov, KB; Medvedeva, NA; Postnikov, AB; Slavutskaia, AV | 1 |
| Adams, SL; Ischiropoulos, H; Leboy, PS; Shapiro, IM; Teixeira, CC | 1 |
| Bledsoe, G; Chao, J; Chao, L; Xia, CF | 1 |
| Ajisaka, R; Iemitsu, M; Kuno, S; Maeda, S; Matsuda, M; Miyauchi, T; Otsuki, T; Sugawara, J; Tanabe, T | 1 |
| Aulaskari, P; Haukka, M; Kotikoski, H; Moilanen, E; Oksala, O; Oresmaa, L; Pohjala, E; Salminen, J; Vainiotalo, P; Vapaatalo, H | 1 |
| Del Olmo, JA; Felipo, V; Kosenko, E; Montoliu, C; Rodrigo, JM; Serra, MA | 1 |
| Chen, J; El Chaar, M; Felsen, D; Gallagher, R; Ito, K; Khodadadian, JJ; Poppas, DP; Seshan, SV; Vaughan, ED | 1 |
| Chang, HR; Chen, HI; Hsu, YH; Hu, CT; Liu, CJ | 1 |
| Fukatsu, A; Funami, J; Hayashi, T; Ignarro, LJ; Iguchi, A; Juliet, PA; Matsui-Hirai, H; Miyazaki, A | 1 |
| Bode-Böger, SM; Kojda, G | 1 |
| Chou, DS; Fong, TH; Hsiao, G; Lin, KH; Shen, MY; Sheu, JR; Tzu, NH; Wang, Y | 1 |
| Dias-Junior, CA; Evora, PR; Moreno, H; Souza-Silva, AR; Tanus-Santos, JE; Uzuelli, JA | 1 |
| Broch, M; Castro, A; Fernández-Real, JM; López-Bermejo, A; Peñarroja, G; Ricart, W; Vázquez, G; Vendrell, J | 1 |
| Eliraz, A; Kerem, Z; Madar, Z; Offer, S; Stark, AH; Weller, JI; Zaslaver, M | 1 |
| Hakam, AC; Hussain, T | 2 |
| Antunes, E; Cardoso, MH; De Nucci, G; Lilla, S; Marcondes, S; Morganti, RP; Murad, F; Thomazzi, SM | 1 |
| Hiroi, T; Ishii, M; Kiuchi, Y; Shimizu, S; Wajima, T | 1 |
| Dias-Junior, CA; Tanus-Santos, JE | 1 |
| Hai, S; Minamiyama, Y; Okada, S; Suehiro, S; Takemura, S | 1 |
| Bidlingmaier, M; Friese, K; Jeschke, U; Kainer, F; Mylonas, I; Schiessl, B; Strasburger, C | 1 |
| Barbosa, F; Gerlach, RF; Sertorio, JT; Tanus-Santos, JE | 1 |
| Aulaskari, P; Haukka, M; Kotikoski, H; Moilanen, E; Oksala, O; Oresmaa, L; Pohjala, E; Vainiotalo, P; Vapaatalo, H | 1 |
| Aubin, MC; Carrier, M; Perrault, LP; Shi, YF; Tardif, JC | 1 |
| Devynck, MA; Iliou, MC; Levenson, J; Pernollet, MG; Simon, A | 1 |
| Metzger, IF; Sertorio, JT; Tanus-Santos, JE | 1 |
| Katayama, S; Kuramochi, T; Ushiyama, M | 1 |
| Alda, JO; Garay, RP; Pereboom, D; Valero, M | 1 |
| Mejía-García, TA; Paes-de-Carvalho, R | 1 |
| Bai, Y; Campese, V; Mortazavi, R; Vaziri, ND; Ye, S | 1 |
| Erceg, S; Felipo, V; Piedrafita, B; Rodrigo, R; Rodriguez-Diaz, J; Saez-Valero, J; Suarez, I | 1 |
| Demirakca, S; Gebhard, MM; Gorenflo, M; Hagl, S; Herpel, E; Klimpel, H; Röhlig, K; Schnabel, PA; Ullmann, MV | 1 |
| Kawachi, H; Kawada, T; Korai, T; Matsui, T; Moriya, NH; Tanaka, SY; Watanabe, M; Yano, H | 1 |
| Fukai, T; Guldberg, RE; Kim, HW; Lin, A; Ushio-Fukai, M | 1 |
| Baker, RS; Clark, K; Eghtesady, P; Ferguson, R; Lam, C; Lombardi, J; McNamara, J | 1 |
| Bauersachs, J; Fleissner, F; Jakob, M; Klink, I; Stichtenoth, DO; Thum, T; Tsikas, D | 1 |
| Dias-Junior, CA; Sertorio, JT; Tanus-Santos, JE | 1 |
| Chou, DS; Fong, TH; Hsiao, G; Lin, KH; Liu, CL; Shen, MY; Sheu, JR | 1 |
| Cui, Y; Geng, B; Tang, C; Zeng, X; Zhang, L | 1 |
| Feelisch, M | 1 |
| Cuvelier, C; Demetter, P; Lefebvre, RA; Timmermans, JP; Van Crombruggen, K; Van Nassauw, L | 1 |
| Blouet, C; Huneau, JF; Mariotti, F; Mathe, V; Tome, D | 1 |
| Benndorf, R; Böger, RH; Förstermann, U; Kahl, L; Li, H; Lüneburg, N; Maas, R; Schwedhelm, E | 1 |
| Biecker, E; Clemens, C; Eckhardt, A; Fischer, N; Heller, J; Hennenberg, M; Lammert, F; Leifeld, L; Pröbsting, AS; Sauerbruch, T; Trebicka, J | 1 |
| Andreadou, I; Fotopoulou, T; Gizas, V; Iliodromitis, EK; Koufaki, M; Kremastinos, DT; Papapetropoulos, A; Pyriochou, A; Tsotinis, A; Zoga, A | 1 |
| Caldas-Bussiere, MC; Costa, FR; Dias, BL; Escocard, RM; Faes, MR; Viana, KS | 1 |
| Bopp, C; Busch, C; Hofer, S; Klein, A; Martin, E; Spöhr, F; Weigand, MA | 1 |
| Argiolas, A; Boi, A; Cocco, C; Ferri, GL; Melis, MR; Melis, T; Sanna, F; Succu, S | 1 |
| Chen, HI; Hsieh, NK; Liu, DD; Yang, YL | 1 |
| Banach, M; Goch, A; Goch, JH; Mikhailidis, DP; Rysz, J | 1 |
| Leoncini, G; Segantin, A; Signorello, MG | 1 |
| Li, W; Lou, TF; Mackie, A; Pace, BS; Singh, M | 1 |
| Kato, T; Kurahashi, H; Nishizawa, H; Pryor-Koishi, K; Sekiya, T; Suzuki, M; Tada, S; Udagawa, Y | 1 |
| Kim, JM; Kim, SY; Koo, JY; Koo, YK; Oh, D; Park, S; Yun-Choi, HS | 1 |
| Hyndman, KA; Pardieck, JL; Pollock, JS; Sullivan, JC | 1 |
| Cauli, O; Felipo, V; Garcia-Verdugo, JM; Gómez-Pinedo, U; Herraiz, S; Pellicer, A; Pellicer, B; Rodrigo, R | 1 |
| Ahabrach, H; Boix, J; ElMlili, N; Errami, M; Felipo, V; Rodrigo, R | 1 |
| Felipo, V; Llansola, M | 1 |
| Kuz'menko, GN; Peretiatko, LP; Popova, IG; Sharygin, SA; Sitnikova, OG | 1 |
| Ahluwalia, A; Duchene, J; Hattori, N; Milsom, AB; Panayiotou, C; Urabe, T; Yamashiro, K | 1 |
| Bortolatto, CF; Jesse, CR; Nogueira, CW; Rocha, JB; Wilhelm, EA | 1 |
| Ahluwalia, A; Akram, F; Arghandawi, S; Benjamin, N; Hobbs, AJ; Kapil, V; Loukogeorgakis, S; Macallister, R; Maleki-Toyserkani, S; Milsom, AB; Okorie, M; Pearl, V; Rehman, F; Webb, AJ | 1 |
| de Hoon, JN; Depré, M; Van der Schueren, BJ; Van Hecken, A; Verbesselt, R; Verbrugge, FH | 1 |
| Jordan, J; Stichtenoth, DO; Tsikas, D | 1 |
| Jou, NT; Li, XY; Ma, SX; Smith, BT | 1 |
| Hori, M; Horiguchi, K; Iizuka, M; Kajita, M; Murata, T; Ozaki, H | 1 |
| Borniquel, S; Ekblom, B; Larsen, FJ; Lundberg, JO; Sahlin, K; Schiffer, TA; Weitzberg, E | 1 |
| Akaike, T; Ihara, H; Sawa, T | 1 |
| Aubin, MC; Carrier, M; Forcillo, J; Maltais, S; Perrault, LP; Shi, YF; Tardif, JC | 1 |
| Cai, Y; Liu, H; Ma, J; Purdy, RE; Ren, XL; Wang, ZC; Yu, JW; Zhang, R; Zhang, YY | 1 |
| Batalhao, ME; Branco, LG; Carnio, EC; Coimbra, TM; Francescato, HD; Kwiatkoski, M; Soriano, RN | 1 |
| Ahl, D; Grapensparr, L; Holm, L; Jädert, C; Lundberg, JO; Massena, S; Petersson, J; Phillipson, M | 1 |
| Amaral, JH; Costa-Filho, AJ; Marçal, DM; Montenegro, MF; Palei, AC; Pinheiro, LC; Tanus-Santos, JE | 1 |
| Ahluwalia, A; Baliga, RS; Ghosh, SM; Hobbs, AJ; Macallister, RJ; Milsom, AB; Trinder, SL | 1 |
| Manral, A; Saini, V; Sharma, DK; Singh, A; Srinivasan, BP; Tiwari, M | 1 |
| Heiss, C; Hendgen-Cotta, UB; Kelm, M; Kropp, M; Luedike, P; Lundberg, JO; Niessen, M; Rammos, C; Rassaf, T; Schicho, A; Stock, P; Totzeck, M; Weitzberg, E | 1 |
| Larsen, FJ; Lindholm, P; Lundberg, JO; Schiffer, TA; Weitzberg, E | 1 |
| Kolankaya, D; Korkmaz, A | 1 |
| Abassi, Z; Abu-Saleh, N; Awad, H; Azzam, ZS; Bishara, B; Karram, T; Khamaysi, I; Naffaa, M | 1 |
| Akaike, T; Iwai, S; Joudoi, T; Kamizono, N; Sawa, T; Shichiri, Y; Yamada, N; Yoshitake, J | 1 |
| Abad, E; Garcia-Dorado, D; Hernando, V; Inserte, J; Poncelas-Nozal, M; Vilardosa, Ú | 1 |
| Aboud, Z; Ahluwalia, A; Davies, S; Ghosh, SM; Kapil, V; Khambata, RS; McKnight, A; Poole, A; Velmurugan, S; Webb, AJ | 1 |
| Grushin, K; Huang, CC; Ko, GY; Ko, ML; Park, SY; Shi, L | 1 |
| Anderson, RA; Bundhoo, S; James, PE; Sagan, E | 1 |
| Alvares, TS; Conte-Junior, CA; Paschoalin, VM; Silva, JT | 1 |
| Ambrosio, SR; Batalhão, ME; Carnio, EC; Pernomian, L; Simão, MR; Simplicio, JA; Tirapelli, CR | 1 |
| Baxter, GF; Bice, JS; Burley, DS | 1 |
| Apostoli, GL; Emerson, M; Smallwood, MJ; Solomon, A; Winyard, PG | 1 |
| Carresi, C; Dagostino, C; Giancotti, LA; Gliozzi, M; Gratteri, S; Malara, N; Mollace, V; Muscoli, C; Muscoli, S; Musolino, V; Palma, E; Romeo, F; Sacco, I; Salvemini, D; Visalli, V; Vitale, C | 1 |
| Ashmore, T; Feelisch, M; Fernandez, BO; Griffin, JL; Kotwica, AO; Murfitt, SA; Murray, AJ; Roberts, LD | 1 |
| Eriksson, K; Larsson, AC; Lindholm, P; Nihlén, C; Schiffer, T; Uusijärvi, J; Weitzberg, E | 1 |
| Hay, ID; Rehm, BH; Rehman, ZU; Wang, Y | 1 |
| Andre, T; McKinley-Barnard, S; Morita, M; Willoughby, DS | 1 |
| Cao, B; Mukherjee, M; Shukal, S; Wu, Y | 1 |
| Leung, SW; Vanhoutte, PM; Zhao, Y | 1 |
| Ashmore, T; Branco, C; Clarke, K; Cowburn, AS; Feelisch, M; Fernandez, BO; Finnerty, J; Griffin, JL; Johnson, RS; Kotwica, AO; Morash, AJ; Murfitt, SA; Murray, AJ; Roberts, LD; West, JA | 1 |
| Bárány, P; Békássy, Z; Cananau, C; Carlström, M; Checa, A; Hansson, S; Krmar, RT; Lundberg, JO; Sartz, L; Svensson, A; Weitzberg, E; Westphal, S; Wheelock, CE; Wide, K | 1 |
| Lau, YS; Ling, WC; Murugan, DD; Mustafa, MR; Vanhoutte, PM | 1 |
| Beall, CM; Cheong, HI; Erzurum, SC; Garchar, AC; Gebremedhin, A; Janocha, AJ; Monocello, LT | 1 |
| Borisov, AV; Mokrousov, IS; Perfilova, VN; Prokofiev, II; Tyurenkov, IN | 1 |
| Coggan, AR; Peterson, LR | 1 |
| Fotopoulou, T; Fransén, K; Grenegård, M; Kardeby, C; Koufaki, M; Paramel, GV; Pournara, D; Sirsjö, A | 1 |
| Gilmer, JF; Medina, C; O'Sullivan, S; Radomski, MW; Wang, J | 1 |
| Amaral, L; Baik, C; Cornelius, DC; Giachelli, C; Greer, M; Herrock, OT; Ibrahim, T; Jackson, C; Tardo, GA; Travis, OK; Williams, JM | 1 |
| González, JM; Krell, T; Martín-Mora, D; Martín-Rodríguez, AJ; Reyes-Darias, JA; Römling, U | 1 |
| Bessho, S; Buttaro, BA; Grando, K; Miller, AL; Nicastro, LK; Queisser, G; Tükel, Ç; White, AP; Zhang, Y | 1 |
| Akaike, T; Carlström, M; Catrina, SB; Collado, A; Cortese-Krott, MM; Jiao, T; Lundberg, JO; Mahdi, A; Mergia, E; Pernow, J; Sundqvist, ML; Tengbom, J; Tratsiakovich, Y; Weitzberg, E; Yang, J; Zheng, X; Zhou, Z | 1 |
15 review(s) available for nitrates and cyclic gmp
| Article | Year |
|---|---|
[Organic nitrates. New knowledge about the mechanism of action of an old class of substances].
Topics: Angina Pectoris; Coronary Circulation; Coronary Disease; Cyclic GMP; Cytochrome P-450 Enzyme System; Humans; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide | 1992 |
Similarity and dissimilarity in the mode and mechanism of action between nicorandil and classical nitrates: an overview.
Topics: Animals; Arteries; Coronary Vessels; Cyclic GMP; Heart; Hemodynamics; Ion Channels; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Potassium; Vasodilator Agents; Veins | 1987 |
[Nitrate tolerance].
Topics: Coronary Disease; Cyclic GMP; Drug Tolerance; Enzyme Activation; Guanylate Cyclase; Hemodynamics; Humans; Nitrates; Water-Electrolyte Balance | 1988 |
Mode of action of nitrates at the cellular level.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cyclic GMP; Humans; Muscle Proteins; Muscle, Smooth, Vascular; Nitrates; Protein Kinases; Sarcolemma; Vasodilation | 1986 |
Nitrates. Mode of action at a cellular level.
Topics: Calcium; Cyclic GMP; Humans; Nitrates | 1987 |
Nitrate tolerance from a biochemical point of view.
Topics: Cyclic GMP; Drug Tolerance; Humans; Kinetics; Nitrates; Receptors, Drug | 1987 |
Some pharmacological properties of organic nitrates.
Topics: Angina Pectoris; Animals; Arterioles; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Drug Tolerance; Humans; Inactivation, Metabolic; Isosorbide Dinitrate; Liver; Muscle, Smooth, Vascular; Myocardium; Nitrates; Nitroglycerin; Oxyhemoglobins; Vasodilation; Venous Pressure | 1984 |
Vasomotion of coronary arteries: from nitrates to nitric oxide.
Topics: Arteriosclerosis; Biological Factors; Cardiovascular Agents; Clinical Trials as Topic; Coronary Vessels; Cyclic GMP; Humans; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
*NO, RSNO, ONOO-, NO+, *NOO, NOx--dynamic regulation of oxidant scavenging, nitric oxide stores, and cyclic GMP-independent cell signaling.
Topics: Animals; Cyclic GMP; Free Radical Scavengers; Humans; Nitrates; Nitric Oxide; Signal Transduction | 2001 |
Nitrates and NO release: contemporary aspects in biological and medicinal chemistry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Cations; Cyclic GMP; Drug Design; Drug Tolerance; Endothelium, Vascular; Free Radicals; Guanylate Cyclase; Humans; Molecular Structure; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroglycerin; Oxidation-Reduction; Sulfhydryl Compounds; Vasodilator Agents | 2004 |
Organic nitrates in cardiovascular disease.
Topics: Angina, Unstable; Animals; Cardiovascular Diseases; Cyclic GMP; Enalapril; Endothelium, Vascular; Hemodynamics; Humans; Myocardial Infarction; Nitrates; Nitric Oxide; Nitroglycerin; Platelet Aggregation | 2005 |
Antioxidant effect of a nitrated cyclic nucleotide functioning as an endogenous electrophile.
Topics: Adipocytes; Animals; Antioxidants; Chromatography, High Pressure Liquid; Cyclic GMP; Cysteine; Electrons; Endothelial Cells; Heme Oxygenase-1; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Mice; Nitrates; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Signal Transduction; Tandem Mass Spectrometry; Up-Regulation | 2011 |
Novel approaches and opportunities for cardioprotective signaling through 3',5'-cyclic guanosine monophosphate manipulation.
Topics: Cyclic GMP; Guanylate Cyclase; Heme Oxygenase (Decyclizing); Humans; Natriuretic Peptides; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Phosphodiesterase Inhibitors; Receptors, Adrenergic, beta-3; Receptors, Cytoplasmic and Nuclear; Reperfusion Injury; Signal Transduction; Soluble Guanylyl Cyclase | 2014 |
Vascular nitric oxide: Beyond eNOS.
Topics: Animals; Arginine; Cardiovascular Diseases; Cell Physiological Phenomena; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Humans; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; S-Nitrosothiols; Signal Transduction | 2015 |
Dietary Nitrate Enhances the Contractile Properties of Human Skeletal Muscle.
Topics: Animals; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Diet; Humans; Muscle Contraction; Muscle, Skeletal; Nitrates; Nitric Oxide; Ryanodine Receptor Calcium Release Channel; Signal Transduction | 2018 |
30 trial(s) available for nitrates and cyclic gmp
| Article | Year |
|---|---|
Exercise increases systemic nitric oxide production in men.
Topics: Adult; Analysis of Variance; Atrial Natriuretic Factor; Creatinine; Cyclic GMP; Exercise; Exercise Test; Humans; Male; Nitrates; Nitric Oxide; Physical Endurance; Regression Analysis | 1994 |
Increased nitric oxide production in patients with hypotension during hemodialysis.
Topics: Aged; Cyclic GMP; Endothelins; Female; Heparin; Humans; Hypotension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Regression Analysis; Renal Dialysis | 1995 |
L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects.
Topics: Adult; Arginine; Cyclic GMP; Double-Blind Method; Gas Chromatography-Mass Spectrometry; Heart Rate; Humans; Male; Nitrates; Nitrites; Platelet Aggregation; Platelet Aggregation Inhibitors; Vascular Resistance | 1994 |
Nitric oxide may mediate the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency. A double-blind, placebo-controlled study.
Topics: Adult; Blood Pressure; Cardiac Output; Cyclic GMP; Female; Growth Hormone; Heart Rate; Humans; Insulin-Like Growth Factor I; Lipids; Male; Nitrates; Nitric Oxide; Recombinant Proteins; Vascular Resistance | 1996 |
Effects of chronic exercise and deconditioning on platelet function in women.
Topics: Adult; Blood Platelets; Blood Pressure; Calcium; Cyclic GMP; Exercise; Female; Heart Rate; Humans; Nitrates; Nitric Oxide; Nitrites; Physical Fitness; Platelet Function Tests; Progesterone | 1997 |
Preventive effects of angiotensin-converting enzyme inhibitors on nitrate tolerance during continuous transdermal application of nitroglycerin in patients with chronic heart failure.
Topics: Administration, Cutaneous; Aged; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Platelets; Blood Pressure; Body Weight; Chronic Disease; Cyclic GMP; Drug Tolerance; Female; Forearm; Heart Failure; Heart Rate; Hematocrit; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Norepinephrine; Regional Blood Flow; Renin; Systole; Vasodilator Agents | 1998 |
Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease.
Topics: Aged; Aged, 80 and over; Alprostadil; Arginine; Arterial Occlusive Diseases; Blood Flow Velocity; Chronic Disease; Cyclic GMP; Double-Blind Method; Exercise Test; Female; Femoral Artery; Follow-Up Studies; Humans; Infusions, Intravenous; Intermittent Claudication; Leg; Male; Middle Aged; Nitrates; Nitric Oxide; Peripheral Vascular Diseases; Treatment Outcome; Ultrasonography, Doppler, Duplex; Vasodilation; Vasodilator Agents | 1998 |
L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship.
Topics: Administration, Oral; Adult; Arginine; Blood Pressure; Cardiac Output; Cyclic GMP; Double-Blind Method; Heart Rate; Humans; Injections, Intravenous; Male; Nitrates; Nitric Oxide; Vasodilation | 1998 |
Down-regulation of nitric oxide production by ibuprofen in human volunteers.
Topics: Adult; Blood Pressure; Carbon Dioxide; Cross-Over Studies; Cyclic GMP; Endotoxins; Female; Heart Rate; Humans; Ibuprofen; Infusions, Intravenous; Male; Nitrates; Nitric Oxide; Nitroprusside; Pulmonary Alveoli; Reproducibility of Results; Single-Blind Method | 1999 |
Indices of activity of the nitric oxide system in hemodialysis patients.
Topics: Arginine; Blood Pressure; Citrulline; Cyclic GMP; Diet; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Renal Dialysis; Second Messenger Systems | 1999 |
Randomized, double-blind, placebo-controlled study of arginine supplementation in chronic renal failure.
Topics: Adolescent; Adult; Amino Acids; Arginine; Cyclic GMP; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Placebos; Proteinuria; Renal Circulation | 1999 |
Role of nitric oxide in the vasodilator effect of recombinant human growth hormone in patients with dilated cardiomyopathy.
Topics: Cardiomyopathy, Dilated; Chi-Square Distribution; Cyclic GMP; Double-Blind Method; Female; Growth Hormone; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Nitrates; Nitric Oxide; Regression Analysis | 2000 |
Diurnal variation of flow-mediated vasodilation in healthy premenopausal women.
Topics: Adult; Blood Pressure; Brachial Artery; Catecholamines; Circadian Rhythm; Cyclic GMP; Endothelium, Vascular; Female; Heart Rate; Humans; Hydrocortisone; Lipids; Nitrates; Nitric Oxide; Nitroglycerin; Premenopause; Reference Values; Vasodilation; Vasodilator Agents | 2000 |
Early alteration in glomerular reserve in humans at genetic risk of essential hypertension: mechanisms and consequences.
Topics: Adult; Amino Acids; Arginine; Cyclic GMP; Female; Genetic Markers; Glomerular Filtration Rate; Humans; Hypertension; Infusions, Intravenous; Insulin; Insulin Resistance; Kidney Glomerulus; Kidney Tubules, Proximal; Lithium Carbonate; Male; Middle Aged; Nitrates; Nitrites; Phenotype; Risk Factors; Second Messenger Systems | 2001 |
Atrial natriuretic peptide infusion and nitric oxide inhalation in patients with acute respiratory distress syndrome.
Topics: Administration, Inhalation; Adult; Aged; Atrial Natriuretic Factor; Cross-Over Studies; Cyclic GMP; Endothelin-1; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Nitrates; Nitric Oxide; Pulmonary Gas Exchange; Respiration, Artificial; Respiratory Distress Syndrome; Vasodilator Agents | 2001 |
Effect of salt intake on endothelium-derived factors in a group of patients with essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure Monitoring, Ambulatory; Cyclic GMP; Diet, Sodium-Restricted; Endothelins; Female; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitrites; Normal Distribution; Renin; Single-Blind Method; Sodium Chloride, Dietary; Statistics, Nonparametric | 2001 |
Cerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days.
Topics: Aged; Brachial Artery; Cyclic GMP; Diabetes Complications; Diabetes Mellitus; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Male; Nitrates; Nitrites; Pyridines; Time Factors; Treatment Outcome; Vasodilation | 2001 |
Effect of diabetes on nitric oxide metabolism during cardiac surgery.
Topics: Aged; Blood Glucose; Coronary Artery Bypass; Creatinine; Cyclic GMP; Diabetes Mellitus; Female; Humans; Insulin; Intraoperative Period; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Single-Blind Method | 2001 |
Paradoxical decrease in plasma NOx by L-arginine load in diabetic and non-diabetic subjects.
Topics: Arginine; Blood Glucose; Blood Pressure; Cyclic GMP; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites | 2002 |
Platelet nitric oxide and superoxide release during the development of nitrate tolerance: effect of supplemental ascorbate.
Topics: Adult; Antioxidants; Ascorbic Acid; Blood Platelets; Cross-Over Studies; Cyclic GMP; Double-Blind Method; Drug Tolerance; Free Radicals; Hemodynamics; Humans; Male; Middle Aged; NAD; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroglycerin; Superoxides; Time Factors; Vasodilator Agents | 2002 |
Effect of transdermal nitroglycerin on inflammatory mediators in patients with peripheral atherosclerotic vascular disease.
Topics: Administration, Cutaneous; Adult; Aged; Anti-Inflammatory Agents; Arteriosclerosis; Biomarkers; C-Reactive Protein; Cyclic GMP; Double-Blind Method; E-Selectin; Female; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Middle Aged; Nitrates; Nitrites; Nitroglycerin; Peripheral Vascular Diseases; Pilot Projects; Statistics, Nonparametric; Vascular Cell Adhesion Molecule-1; Vasculitis; Vasodilator Agents | 2003 |
Moderate regular exercise increases basal production of nitric oxide in elderly women.
Topics: Aged; Cyclic GMP; Exercise; Female; Humans; Life Style; Middle Aged; Nitrates; Nitric Oxide; Nitrites | 2004 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Blind Method; Female; Heart Rate; Humans; Hyperemia; Hypertension; Hypotension; Life Style; Male; Nitrates; Nitric Oxide; Nitrites; Posture; Potassium Chloride; Potassium Compounds; Prevalence; Random Allocation; Risk Factors; Sex Characteristics; Systole | 2010 |
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.
Topics: Area Under Curve; Arginine; Biomarkers; Citrulline; Cyclic GMP; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites | 2010 |
Dietary inorganic nitrate improves mitochondrial efficiency in humans.
Topics: Adult; Cyclic GMP; Dietary Supplements; Double-Blind Method; Exercise; Humans; Ion Channels; Male; Mitochondria; Mitochondrial Proteins; Nitrates; Nitrites; Oxidative Phosphorylation; Oxygen Consumption; Uncoupling Protein 3 | 2011 |
Effects of dietary inorganic nitrate on static and dynamic breath-holding in humans.
Topics: Adult; Apnea; Blood Pressure; Breath Holding; Cyclic GMP; Dietary Supplements; Double-Blind Method; Ergometry; Expiratory Reserve Volume; Humans; Male; Middle Aged; Nitrates; Oxygen Consumption; Pulmonary Gas Exchange; Respiration; Time Factors; Vital Capacity; Young Adult | 2013 |
Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex.
Topics: Adolescent; Adult; Beta vulgaris; Blood Platelets; Cardiovascular Diseases; Collagen; Cross-Over Studies; Cyclic GMP; Diet; Dietary Supplements; Epinephrine; Erythrocytes; Female; Guanylate Cyclase; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium Compounds; Sex Factors; Vegetables; Young Adult | 2013 |
L-arginine does not improve biochemical and hormonal response in trained runners after 4 weeks of supplementation.
Topics: Adult; Ammonia; Arginine; Cyclic GMP; Dietary Supplements; Double-Blind Method; Exercise; Female; Hormones; Human Growth Hormone; Humans; Hydrocortisone; Insulin; Insulin-Like Growth Factor I; Lactic Acid; Male; Nitrates; Nitric Oxide; Nitrites; Placebos; Running | 2014 |
Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis.
Topics: Adolescent; Adult; Animals; Arginine; Biomarkers; Body Mass Index; Citrulline; Cyclic GMP; Dietary Supplements; Double-Blind Method; Glutathione; Healthy Volunteers; Human Umbilical Vein Endothelial Cells; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Resistance Training; Young Adult | 2015 |
Hypoxic erythrocytes mediate cardioprotection through activation of soluble guanylate cyclase and release of cyclic GMP.
Topics: Animals; Cardiotonic Agents; Cyclic GMP; Erythrocytes; Humans; Hypoxia; Mice; Myocytes, Cardiac; Nitrates; Nitric Oxide; Rats; Soluble Guanylyl Cyclase | 2023 |
322 other study(ies) available for nitrates and cyclic gmp
| Article | Year |
|---|---|
Increased guanylate cyclase activity and guanosine 3',5'-monophosphate content in ethionine-induced hepatomas.
Topics: Adenylyl Cyclases; Animals; Azides; Carcinoma, Hepatocellular; Cell Division; Cyclic AMP; Cyclic GMP; Ethionine; Guanylate Cyclase; Hydroxylamines; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrates; Rats | 1977 |
Ammonium and sulfate ion release of histamine from lung fragments.
Topics: Acetates; Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Ammonium Chloride; Ammonium Sulfate; Animals; Cyclic AMP; Cyclic GMP; Guinea Pigs; Haplorhini; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Lung; Nitrates; Quaternary Ammonium Compounds; Spectrometry, Fluorescence; SRS-A; Sulfates | 1975 |
Pharmacodynamic modeling of the in vitro vasodilating effects of organic mononitrates.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Isomerism; Male; Mathematics; Models, Biological; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Rats; Rats, Inbred Strains; Vasodilator Agents | 1992 |
L-arginine infusion induces hypotension and diuresis/natriuresis with concomitant increased urinary excretion of nitrite/nitrate and cyclic GMP in humans.
Topics: Adult; Arginine; Blood Pressure; Cyclic GMP; Diuresis; Heart Rate; Humans; Male; Natriuresis; Nitrates; Nitrites; Nitrogen Oxides; Vasodilation | 1992 |
Inhibition of nitrovasodilator- and acetylcholine-induced relaxation and cyclic GMP accumulation by the cytochrome P-450 substrate, 7-ethoxyresorufin.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Aorta; Biotransformation; Cyclic GMP; Cytochrome P-450 Enzyme System; Drug Interactions; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxazines; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1992 |
Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin.
Topics: Amino Acid Oxidoreductases; Arginine; Cyclic GMP; Cytokines; Endotoxins; Humans; Lipopolysaccharides; Liver; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Recombinant Proteins | 1992 |
Norepinephrine increases cyclic GMP in astrocytes by a mechanism dependent on nitric oxide synthesis.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Cyclic GMP; Intracellular Fluid; Kinetics; Nitrates; Nitric Acid; Nitric Oxide; Norepinephrine; Rats; Rats, Inbred Strains | 1991 |
Comparison of nicorandil-induced relaxation, elevations of cyclic guanosine monophosphate and stimulation of guanylate cyclase with organic nitrate esters.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Activation; Esters; Female; Guanylate Cyclase; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Nitric Oxide; Nitroglycerin; Stimulation, Chemical; Vasodilator Agents | 1991 |
Reduced nitric oxide release causes nitrate tolerance in the intact coronary circulation.
Topics: Animals; Bradykinin; Cell Line; Coronary Vessels; Cyclic GMP; Drug Tolerance; Fibroblasts; Heart; Iloprost; Lung; Molsidomine; Myocardium; Nitrates; Nitric Oxide; Nitroglycerin; Rabbits; Rats; Vasodilator Agents | 1991 |
Synthesis and action of nitric oxide in rat glomerular mesangial cells.
Topics: Animals; Cells, Cultured; Cyclic GMP; Escherichia coli; Interferons; Kidney Glomerulus; Lipopolysaccharides; Nitrates; Nitric Oxide; Nitrites; Rats | 1991 |
Tumor necrosis factor alpha activates soluble guanylate cyclase in bovine glomerular mesangial cells via an L-arginine-dependent mechanism.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Enzyme Activation; Glomerular Mesangium; Guanylate Cyclase; Humans; Interferon-gamma; Interleukin-1; Kinetics; Nitrates; Nitrites; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1990 |
L-arginine, but not N alpha-benzoyl-L-arginine ethyl ester, is a precursor of endothelium-derived relaxing factor.
Topics: Acetylcholine; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Acid; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Pulmonary Artery | 1990 |
Inhibition of platelet activating factor-induced platelet aggregation by molsidomine, SIN-1, and nitrates in vitro and ex vivo.
Topics: Cyclic GMP; Enzyme Activation; In Vitro Techniques; Molsidomine; Nitrates; Nitric Oxide; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Vasodilator Agents | 1989 |
Effect of pertussis toxin and the cGMP lowering agent LY83583 on the relaxation induced by nitrates in isolated bovine mesenteric artery. A comparison between glyceryl trinitrate, isosorbide dinitrate and isosorbide 5-mononitrate.
Topics: Aminoquinolines; Animals; Cattle; Cyclic GMP; Isosorbide Dinitrate; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Pertussis Toxin; Vascular Resistance; Virulence Factors, Bordetella | 1989 |
Cellular mechanisms of nitrate action.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; Glutathione; Guanylate Cyclase; Nitrates; Nitric Oxide; Rats; Sulfhydryl Compounds; Vascular Resistance | 1989 |
Effects of atrial natriuretic polypeptide and organic nitrates on levels of relaxation and cyclic nucleotide of canine coronary artery with and without endothelial injury.
Topics: Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dogs; Endothelium, Vascular; Isosorbide Dinitrate; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Vasodilation | 1988 |
Mode of action of nitrates with regard to vasodilatation and tolerance.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Nitrates; Nitroglycerin; Vasodilation | 1986 |
Mechanism of vasodilation by nitrates: role of cyclic GMP.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Molsidomine; Nitrates; Nitroglycerin; Vasodilator Agents | 1987 |
Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation, and guanylate cyclase activation by glyceryl trinitrate and the enantiomers of isoidide dinitrate.
Topics: Animals; Aorta; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Guanylate Cyclase; Male; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Rats; Rats, Inbred Strains; Stereoisomerism; Sugar Alcohols; Vasodilation | 1988 |
Desensitization of guanylate cyclase in nitrate tolerance does not impair endothelium-dependent responses.
Topics: Animals; Aorta, Thoracic; Biological Factors; Cattle; Cells, Cultured; Cyclic GMP; Drug Tolerance; Endothelium, Vascular; Enzyme Activation; Female; Guanylate Cyclase; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Rabbits; Sulfhydryl Compounds; Vasodilation | 1988 |
Mechanisms of nitrate-induced vasodilatation and tolerance on a biochemical base.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Pressure; Cattle; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Isosorbide Dinitrate; Methylene Blue; Nitrates; Nitroglycerin; Nitroprusside; Vasodilation | 1985 |
[Mechanism of the vasodilating effect and blood platelet- antiaggregating activity of molsidomine and SIN-1].
Topics: Animals; Cyclic GMP; Molsidomine; Muscle, Smooth, Vascular; Nitrates; Platelet Aggregation; Vasodilation | 1987 |
Mechanism of nitrate-induced vasodilation and tolerance.
Topics: Animals; Cattle; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Nitrates; Nitroglycerin; Vasodilation | 1983 |
The effects of dilazep and SG 75 on cyclic nucleotides in the coronary artery.
Topics: Adenosine; Animals; Arteries; Azepines; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dilazep; Dogs; Muscle Contraction; Myocardium; Niacinamide; Nicorandil; Nitrates; Vasodilator Agents | 1980 |
Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Dexamethasone; Disease Models, Animal; Homoarginine; Hypertension; Insulin; Male; Nitrates; Nitric Oxide; Ornithine; Rats; Rats, Inbred Strains | 1993 |
Dexamethasone inhibits nitric oxide synthase mRNA induction by interleukin-1 alpha and tumor necrosis factor-alpha in vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Blotting, Northern; Cells, Cultured; Cyclic GMP; Dexamethasone; Drug Synergism; Enzyme Induction; Interleukin-1; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Recombinant Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha | 1993 |
Nitric oxide, superoxide and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Mice; Molsidomine; N-Methylaspartate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1993 |
Role of vascular nitric oxide synthase in endotoxin shock of Propionibacterium acnes-sensitized rats.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; Dexamethasone; Enzyme Induction; Heart Rate; Hepatectomy; Hypersensitivity; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Propionibacterium acnes; Rats; Rats, Wistar; Shock, Septic; Splenectomy; Survival Analysis; Tissue Distribution | 1994 |
Nitric oxide as a mediator of oxidant lung injury due to paraquat.
Topics: Amino Acid Oxidoreductases; Animals; Calcium; Citrulline; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidants; Paraquat; Perfusion; Respiration | 1994 |
Renal hemodynamic effects of dietary protein in the rat: role of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Dietary Proteins; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasodilation | 1995 |
Cyclic nucleotide dependent phosphorylation of neuronal nitric oxide synthase inhibits catalytic activity.
Topics: Amino Acid Oxidoreductases; Catalysis; Cells, Cultured; Cyclic AMP; Cyclic GMP; Electrophoresis; Humans; Neurons; Nitrates; Nitric Oxide Synthase; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Kinases | 1994 |
Further characterization and comparison of inducible nitric oxide synthase in mouse, rat, and human hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Dexamethasone; Enzyme Induction; Gene Expression; Humans; Interferon-gamma; Interleukin-1; Interleukins; Isoenzymes; Lipopolysaccharides; Liver; Mice; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Recombinant Proteins; RNA, Messenger; Species Specificity; Tumor Necrosis Factor-alpha | 1995 |
Modulation of particulate nitric oxide synthase activity and peroxynitrite synthesis in cholesterol enriched endothelial cell membranes.
Topics: Amino Acid Oxidoreductases; Animals; Cattle; Cell Membrane; Cholesterol; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Manganese; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Superoxides | 1995 |
Effect of graded hypoxia on the induction and function of inducible nitric oxide synthase in rat mesangial cells.
Topics: Amino Acid Oxidoreductases; Animals; Blotting, Northern; Calmodulin-Binding Proteins; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Enzyme Induction; Glomerular Mesangium; In Vitro Techniques; NADPH Dehydrogenase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; RNA, Messenger | 1995 |
Erythrocyte stages of Plasmodium falciparum exhibit a high nitric oxide synthase (NOS) activity and release an NOS-inducing soluble factor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Factors; Canavanine; Cell Adhesion; Cells, Cultured; Citrulline; Culture Media, Conditioned; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Erythrocytes; Host-Parasite Interactions; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Plasmodium; Plasmodium falciparum; Protozoan Proteins; Species Specificity; Umbilical Veins | 1995 |
Peroxynitrite-induced accumulation of cyclic GMP in endothelial cells and stimulation of purified soluble guanylyl cyclase. Dependence on glutathione and possible role of S-nitrosation.
Topics: Animals; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Glutathione; Guanylate Cyclase; Nitrates; Nitric Oxide; Nitroso Compounds; S-Nitrosoglutathione; Swine | 1995 |
Nitric oxide biosynthesis during pregnancy: implications for circulatory changes.
Topics: Animals; Cyclic AMP; Cyclic GMP; Female; Immunohistochemistry; In Situ Hybridization; Membrane Potentials; Methacholine Chloride; Nitrates; Nitric Oxide; Phenylephrine; Pregnancy; Pregnancy, Animal; Rats; Time Factors; Urination | 1995 |
Identification of increased nitric oxide biosynthesis during pregnancy in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cyclic GMP; Diet; Female; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Pregnancy, Animal; Rats | 1993 |
Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Northern; Calcium; Calmodulin; Cattle; Cyclic GMP; Endothelins; Endothelium, Vascular; Enzyme Activation; GTP-Binding Proteins; Inosine Triphosphate; Iodine Radioisotopes; Nitrates; Nitric Oxide Synthase; Nitrites; Peptide Fragments; Pertussis Toxin; Receptors, Endothelin; Virulence Factors, Bordetella | 1993 |
Nitric oxide activates cyclooxygenase enzymes.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cyclic GMP; Dinoprostone; Enzyme Activation; Guanidines; Humans; Indomethacin; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins | 1993 |
Nitric oxide liberating, soluble guanylate cyclase stimulating and vasorelaxing properties of the new nitrate-compound SPM 3672.
Topics: Animals; Aorta, Thoracic; Coronary Vessels; Cyclic GMP; Cysteine; Guanylate Cyclase; Humans; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Rats; Rats, Wistar; Solubility; Swine; Vasodilator Agents | 1993 |
Effect of nitroprusside on regional cerebral cyclic GMP, blood flow and O2 consumption in rat.
Topics: Animals; Blood Gas Analysis; Brain; Cerebral Cortex; Cerebrovascular Circulation; Cyclic GMP; Hemodynamics; Male; Nitrates; Nitroprusside; Oxygen Consumption; Rats | 1995 |
Effects of prolonged L-arginine administration on blood pressure in patients with essential hypertension (EH).
Topics: Adult; Arginine; Blood Pressure; Cyclic GMP; Fibrinolysis; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Nitrates; Nitrites; Radioimmunoassay | 1995 |
Peroxynitrite stimulates vascular smooth muscle cell cyclic GMP synthesis.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Glutathione; Guanylate Cyclase; Kinetics; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Oxyhemoglobins; Rats | 1995 |
Deficiency of endogenous arginine synthesis provokes hypertension by exhausting substrate arginine for nitric oxide synthesis.
Topics: Amino Acids; Animals; Arginine; Blood Pressure; Creatinine; Cyclic GMP; Eating; Hypertension; Intestine, Small; Muscles; Nitrates; Nitric Oxide; Orotic Acid; Pulse; Rats; Rats, Sprague-Dawley; Reference Values; Weight Loss | 1994 |
Increased urinary nitrate excretion in rats with adjuvant arthritis.
Topics: Animals; Arthritis, Experimental; Chromatography, Gas; Creatinine; Cyclic GMP; Male; Nitrates; Rats; Rats, Sprague-Dawley | 1994 |
Nitrite/nitrate and cytokine levels in bronchoalveolar lavage fluid of lung cancer patients.
Topics: Bronchoalveolar Lavage Fluid; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclic GMP; Cytokines; Humans; Interleukin-1; Interleukin-6; Lung Diseases; Lung Neoplasms; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Phosphatidylcholines; Smoking; Tumor Necrosis Factor-alpha | 1994 |
Role of nitric oxide (EDRF) in radiocontrast acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Arginine; Blood Pressure; Cyclic GMP; Diatrizoate; Female; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley; Sodium; Time Factors | 1994 |
Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells.
Topics: Calcium; Calmodulin; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Humans; Ions; Nitrates; Nitric Oxide; Nitrites; Stress, Mechanical | 1994 |
Long-term administration of L-arginine, L-NAME, and the exogenous NO donor molsidomine modulates urinary nitrate and cGMP excretion in rats.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Cholesterol; Chromatography, Gas; Cyclic GMP; Heart; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Time Factors | 1994 |
Involvement of cyclic AMP and nitric oxide in immunoglobulin E-dependent activation of Fc epsilon RII/CD23+ normal human keratinocytes.
Topics: Antibodies, Monoclonal; Arginine; Cell Division; Cell Separation; Cells, Cultured; Cyclic AMP; Cyclic GMP; Humans; Immunoglobulin E; Immunohistochemistry; In Situ Hybridization; Infant, Newborn; Interleukin-6; Keratinocytes; Male; Nitrates; Nitric Oxide; Receptors, IgE; RNA, Messenger; Signal Transduction; Skin; Tumor Necrosis Factor-alpha | 1994 |
Direct inhibition of platelet function by organic nitrates via nitric oxide formation.
Topics: Adenosine Triphosphate; Animals; Anisotropy; Blood Platelets; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Esters; Fibroblasts; Humans; Lung; Molsidomine; Nitrates; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Thromboxanes | 1993 |
CD-832, a new dihydropyridine derivative with both nitrate-like and Ca2+ channel antagonist vasodilator activities.
Topics: Animals; Aorta, Thoracic; Brain Chemistry; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nifedipine; Nitrates; Rabbits; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Activation of distinct cAMP- and cGMP-dependent pathways by relaxant agents in isolated gastric muscle cells.
Topics: Aminoquinolines; Animals; Arginine; Cell Separation; Colon; Cyclic AMP; Cyclic GMP; Digestive System; Digestive System Physiological Phenomena; Enzyme Activation; Gastric Fundus; Guinea Pigs; Isoproterenol; Muscle Relaxation; Muscles; Nitrates; Nitric Acid; Nitroarginine; Nitroprusside; Protein Kinase C; SRS-A; Vasoactive Intestinal Peptide | 1993 |
Anion manipulation, a novel antiarrhythmic approach: mechanism of action.
Topics: Animals; Anions; Blood Pressure; Bromides; Chlorides; Coronary Circulation; Cyclic AMP; Cyclic GMP; Electrocardiography; Epinephrine; Hydrogen-Ion Concentration; Iodides; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitrates; Rabbits; Rats; Rats, Wistar; Sulfuric Acid Esters; Ventricular Fibrillation; Verapamil | 1993 |
Interactions of nitrovasodilators and atrial natriuretic peptide in isolated dog coronary arteries.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic GMP; Dinoprost; Dogs; Epoprostenol; Female; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Nitroprusside; Oxyhemoglobins; Papaverine; Platelet Aggregation Inhibitors; Vasodilator Agents | 1993 |
Human endothelial cells bioactivate organic nitrates to nitric oxide: implications for the reinforcement of endothelial defence mechanisms.
Topics: Biotransformation; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Humans; Isosorbide Dinitrate; Nitrates; Nitric Oxide; Nitroglycerin; Platelet Aggregation; Time Factors | 1995 |
Cyclic guanosine monophosphate (cGMP), nitrite and nitrate in the cerebrospinal fluid in meningitis, multiple sclerosis and Guillain-Barré syndrome.
Topics: Adult; Biomarkers; Brain; Cyclic GMP; Humans; Meningitis; Middle Aged; Multiple Sclerosis; Nitrates; Nitric Oxide; Nitrites; Polyradiculoneuropathy | 1995 |
Increased urinary NO2-/NO3- and cyclic guanosine monophosphate levels in patients with Bartter's syndrome: relationship to vascular reactivity.
Topics: Adolescent; Adult; Bartter Syndrome; Creatinine; Cyclic GMP; Female; Humans; Hypokalemia; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Vasoconstriction; Vasodilation | 1996 |
Protection against hepatic ischemia/reperfusion injury by exogenous L-arginine.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Liver; Liver Circulation; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury | 1996 |
The new NO donor SPM3672 increases cGMP and improves contraction in rat cardiomyocytes and isolated heart.
Topics: Animals; Cyclic GMP; Cysteine; In Vitro Techniques; Male; Myocardial Contraction; Nitrates; Nitric Oxide; Rats; Rats, Wistar; Vasodilator Agents | 1995 |
Ginsenosides stimulate endogenous production of nitric oxide in rat kidney.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Evaluation Studies as Topic; Ginsenosides; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Panax; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Saponins; Stimulation, Chemical | 1996 |
Nitrite, nitrate and cGMP in the cerebrospinal fluid in degenerative neurologic diseases.
Topics: Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Cyclic GMP; Female; Humans; Male; Middle Aged; Nerve Degeneration; Nervous System Diseases; Nitrates; Nitric Oxide; Nitrites; Parkinson Disease; Spinocerebellar Degenerations | 1995 |
Antithrombotic effects of peroxynitrite: inhibition and reversal of aggregation in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Cyclic GMP; Humans; Nitrates; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Spectrophotometry; Thrombin; Thromboxane A2 | 1995 |
Increased nitric oxide activity in early renovascular hypertension.
Topics: Animals; Blood Pressure; Cyclic GMP; Hypertension, Renovascular; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Reference Values; Regression Analysis; Systole | 1996 |
Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study.
Topics: Amyotrophic Lateral Sclerosis; Citrulline; Cyclic GMP; Cytoplasm; Humans; Immunohistochemistry; Motor Neurons; Neurofilament Proteins; Nitrates; Nitric Oxide; Nitrogen; Oxidation-Reduction; Superoxide Dismutase; Tyrosine | 1996 |
Failure of L-NAME to cause inhibition of nitric oxide synthesis: role of inducible nitric oxide synthase.
Topics: Administration, Oral; Animals; Base Sequence; Blood Vessels; Cyclic GMP; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guinea Pigs; Intestines; Molecular Sequence Data; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Rats | 1996 |
Nitric oxide-donating properties of mesoionic 3-aryl substituted oxatriazole-5-imine derivatives.
Topics: Blood Platelets; Chromatography, High Pressure Liquid; Cyclic GMP; Electron Spin Resonance Spectroscopy; Humans; In Vitro Techniques; Luminescent Measurements; Methemoglobin; Nitrates; Nitric Oxide; Nitrites; Oxyhemoglobins; Platelet Aggregation; Triazoles | 1996 |
Mechanism of ITF 296-induced vasorelaxation compared to nitroglycerin and isosorbide dinitrate: relationship between relaxation of rabbit aorta and tissue cGMP.
Topics: Animals; Aorta, Thoracic; Benzoxazines; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Oxazines; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Cyclic GMP elevation by 5-hydroxytryptamine is due to nitric oxide derived from endogenous nitrosothiol in NG108-15 cells.
Topics: Animals; Cyclic GMP; Glioma; Hybrid Cells; Kinetics; Neuroblastoma; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; Oxyhemoglobins; Serotonin; Sulfhydryl Compounds | 1996 |
Nitric oxide-donating compounds and cyclic GMP depress the spontaneous contractile activity of the isolated rabbit jejunum.
Topics: Analysis of Variance; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Gastrointestinal Motility; Guanylate Cyclase; In Vitro Techniques; Jejunum; Methylene Blue; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxyhemoglobins; Rabbits | 1996 |
Effect of L-arginine on myoglobin-induced acute renal failure in the rabbit.
Topics: Acute Kidney Injury; Animals; Arginine; Creatinine; Cyclic GMP; Male; Myoglobin; Nitrates; Nitrites; Rabbits; Renal Circulation; Vascular Resistance | 1996 |
Nocturnal decreases in nitric oxide and cyclic GMP contents in the chick brain and their prevention by light.
Topics: Animals; Brain; Chickens; Circadian Rhythm; Cyclic GMP; Light; Melatonin; Nitrates; Nitric Oxide; Nitrites | 1996 |
Increase of particulate nitric oxide synthase activity and peroxynitrite synthesis in UVB-irradiated keratinocyte membranes.
Topics: Allosteric Regulation; Calcium; Calmodulin; Cell Membrane; Citrulline; Cyclic GMP; Fluorescence Polarization; Guanylate Cyclase; Humans; Keratinocytes; Kinetics; Microsomes; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species; Temperature; Ultraviolet Rays | 1996 |
Restriction of dietary sodium may enhance nitric oxide production in rats.
Topics: Animals; Arginine Vasopressin; Cyclic GMP; Diet, Sodium-Restricted; Male; Nitrates; Nitric Oxide; Norepinephrine; Rats; Rats, Wistar; Renin; Sodium, Dietary | 1997 |
Interference of carboxy-PTIO with nitric oxide- and peroxynitrite-mediated reactions.
Topics: Animals; Benzoates; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Free Radical Scavengers; Imidazoles; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitrites; Serum Albumin, Bovine; Swine; Tyrosine | 1997 |
Cerebral vasoconstriction in comatose patients resuscitated from a cardiac arrest?
Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Cardiopulmonary Resuscitation; Cerebrovascular Circulation; Coma; Critical Care; Cyclic GMP; Endothelin-1; Female; Heart Arrest; Humans; Male; Middle Aged; Nitrates; Prospective Studies; Vascular Resistance | 1996 |
Nitric oxide stimulates prostaglandin synthesis in cultured rabbit gastric cells.
Topics: Animals; Cells, Cultured; Coloring Agents; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Epoprostenol; Gastric Mucosa; Hemoglobins; Methylene Blue; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nitroprusside; Prostaglandins; Rabbits; Sulfhydryl Reagents | 1997 |
Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Arterial Occlusive Diseases; Cyclic GMP; Disease Progression; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peripheral Vascular Diseases; Vasodilation | 1997 |
3-Morpholino-sydnonimine-induced suppression of human neutrophil degranulation is not mediated by cyclic GMP, nitric oxide or peroxynitrite: inhibition of the increase in intracellular free calcium concentration by N-morpholino-iminoacetonitrile, a metabo
Topics: Acetonitriles; Calcium; Cell Degranulation; Cyclic GMP; Humans; Molsidomine; Morpholines; Neutrophils; Nitrates; Nitric Oxide | 1997 |
Modulation of adenovirus-mediated gene transfer by nitric oxide.
Topics: 3T3 Cells; Adenoviruses, Human; Animals; Antioxidants; beta-Galactosidase; Biopterins; Cell Survival; Cyclic GMP; Enzyme Inhibitors; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; Humans; Luciferases; Lung; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Pteridines; Pterins; Transfection | 1997 |
Endogenous nitric oxide production and atrial natriuretic peptide biological activity in infants undergoing cardiac operations.
Topics: Atrial Natriuretic Factor; Blood Pressure; Cardiopulmonary Bypass; Cyclic GMP; Heart Failure; Heart Septal Defects; Humans; Hypertension, Pulmonary; Infant; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Pulmonary Circulation; Tetralogy of Fallot | 1997 |
Up-regulation of renal and vascular nitric oxide synthase in iron-deficiency anemia.
Topics: Anemia, Iron-Deficiency; Animals; Blotting, Western; Cyclic GMP; Kidney; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Up-Regulation | 1997 |
Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats.
Topics: Animals; Blood Pressure; Cyclic GMP; Enzyme Inhibitors; Glomerular Filtration Rate; GTP Cyclohydrolase; Kidney; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred Strains; Rats, Wistar; RNA, Messenger; Systemic Inflammatory Response Syndrome | 1997 |
Role of exogenous L-arginine in hepatic ischemia-reperfusion injury.
Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Citrulline; Cyclic GMP; Female; Hemodynamics; Liver; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Reperfusion Injury; Swine; Time Factors | 1997 |
Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin.
Topics: Animals; Anticholesteremic Agents; Arginine; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Cyclic GMP; Diet, Atherogenic; Endothelium, Vascular; Hypercholesterolemia; Lovastatin; Male; Nitrates; Nitric Oxide; Rabbits; Superoxides | 1997 |
Inhibition of inducible nitric oxide synthase expression and stimulation of the endothelial formation of nitric oxide most likely accounts for the protective effect of 2-(allylthio)pyrazine in a murine model of endotoxemia.
Topics: Animals; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Enzyme Inhibitors; Lipopolysaccharides; Male; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Organ Culture Techniques; Phenylephrine; Pyrazines; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1997 |
Effect of long-term oral L-arginine on the nitric oxide synthase pathway in the urine from patients with interstitial cystitis.
Topics: Administration, Oral; Arginine; Cyclic GMP; Cystitis, Interstitial; Female; Humans; Nitrates; Nitric Oxide Synthase; Nitrites; Time Factors | 1997 |
Elevated amniotic fluid nitric oxide metabolites and cyclic guanosine 3',5'-monophosphate in pregnant women with intraamniotic infection.
Topics: Adult; Amniotic Fluid; Bacterial Infections; Carboxylic Ester Hydrolases; Cyclic GMP; Female; Humans; Leukocyte Count; Nitrates; Nitric Oxide; Nitrites; Pregnancy; Pregnancy Complications, Infectious; Uterine Diseases | 1997 |
Systemic and renal hemodynamic changes in the luteal phase of the menstrual cycle mimic early pregnancy.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Bicarbonates; Blood Pressure; Blood Volume; Cardiac Output; Chlorides; Cyclic AMP; Cyclic GMP; Female; Follicular Phase; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Humans; Luteal Phase; Nitrates; Nitrites; Norepinephrine; Pregnancy; Reference Values; Regional Blood Flow; Renal Circulation; Renin; Renin-Angiotensin System; Sodium; Vascular Resistance; Vasodilation | 1997 |
Lead-induced hypertension: interplay of nitric oxide and reactive oxygen species.
Topics: Animals; Blood Pressure; Cerebellum; Cerebral Cortex; Cyclic GMP; Endothelin-1; Endothelin-3; Hypertension; Kidney Cortex; Lead; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 1997 |
Plasma levels of nitrite/nitrate and platelet cGMP levels are decreased in patients with atrial fibrillation.
Topics: Aged; Atrial Fibrillation; beta-Thromboglobulin; Blood Platelets; Blood Proteins; Cerebrovascular Disorders; Comorbidity; Cyclic GMP; Diabetes Mellitus; Echocardiography; Female; Fibrinogen; Hemodynamics; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Myocardial Ischemia; Nitrates; Nitric Oxide; Nitrites; Risk Factors; Smoking; Thrombophilia | 1997 |
No changes in cerebrospinal fluid levels of nitrite, nitrate and cyclic GMP with aging. Short communication.
Topics: Adult; Aged; Aging; Cyclic GMP; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites | 1997 |
No cross-tolerance between S-nitrosocaptopril and nitroglycerin in dog coronary arteries in vivo.
Topics: Aldosterone; Animals; Captopril; Coronary Circulation; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Female; Hemodynamics; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Nitrates; Nitric Oxide; Nitroglycerin; Norepinephrine; Peptidyl-Dipeptidase A; Renin; Vasodilator Agents | 1998 |
Intracellular but not extracellular conversion of nitroxyl anion into nitric oxide leads to stimulation of human neutrophil migration.
Topics: Chemotaxis, Leukocyte; Cyclic GMP; Free Radicals; Humans; In Vitro Techniques; Methionine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidants | 1998 |
The deactivation of soluble guanylyl cyclase by redox-active agents.
Topics: Animals; Cattle; Cyclic GMP; Enzyme Activation; Ferricyanides; Guanylate Cyclase; Heme; Kinetics; Methylene Blue; Nitrates; Nitric Oxide; Oxidation-Reduction; Solubility | 1998 |
Nitric oxide superoxide and peroxynitrite modulate osteoclast activity.
Topics: Animals; Animals, Newborn; Bone Resorption; Calcium; Catalase; Cells, Cultured; Cyclic GMP; Enzyme Activation; Hydrogen Peroxide; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Osteoclasts; Rats; Rats, Sprague-Dawley; Superoxides; Thionucleotides | 1998 |
Icodextrin with nitroprusside increases ultrafiltration and peritoneal transport during long CAPD dwells.
Topics: Adult; Aged; Ascitic Fluid; Biological Transport; Cyclic GMP; Dialysis Solutions; Glucans; Glucose; Humans; Icodextrin; Injections, Intraperitoneal; Kinetics; Middle Aged; Molecular Weight; Nitrates; Nitric Oxide; Nitroprusside; Peritoneal Dialysis, Continuous Ambulatory; Ultrafiltration; Vasodilator Agents | 1998 |
Inhibition of rat cardiac muscle contraction and mitochondrial respiration by endogenous peroxynitrite formation during posthypoxic reoxygenation.
Topics: Animals; Bradykinin; Cyclic GMP; Free Radical Scavengers; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Kinetics; Mannitol; Mitochondria, Heart; Myocardial Contraction; Nitrates; Nitric Oxide; Nitroarginine; Oxidants; Oxygen Consumption; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; Sodium Cyanide; Superoxide Dismutase | 1998 |
Enhanced production of nitric oxide may be involved in acute hypotension during maintenance hemodialysis.
Topics: Acute Disease; Anions; Blood Pressure; Cyclic GMP; Endothelin-1; Female; Heart Rate; Humans; Hypotension; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Renal Dialysis; Sympathetic Nervous System | 1998 |
Vitamin C attenuates nitrate tolerance independently of its antioxidant effect.
Topics: Animals; Antioxidants; Ascorbic Acid; Cyclic GMP; Drug Resistance; LLC-PK1 Cells; Nitrates; Nitrogen Oxides; Nitroglycerin; Spermine; Swine | 1998 |
Increased nitric oxide in nasal lavage fluid and nitrotyrosine formation in nasal mucosa--indices for severe perennial nasal allergy.
Topics: Adult; Cyclic GMP; Hemoglobins; Humans; Nasal Lavage Fluid; Nasal Mucosa; Nitrates; Nitric Oxide; Nitrites; Rhinitis, Allergic, Perennial; Tyrosine | 1998 |
Reaction of nitric oxide with superoxide inhibits basolateral K+ channels in the rat CCD.
Topics: Animals; Cell Membrane; Cyclic GMP; Ditiocarb; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Collecting; Membrane Potentials; Nitrates; Nitric Oxide; Nitroprusside; Patch-Clamp Techniques; Penicillamine; Potassium Channels; Potassium Channels, Calcium-Activated; Pyrogallol; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Small-Conductance Calcium-Activated Potassium Channels; Superoxides | 1998 |
Formation of reactive oxygen species by pentaerithrityltetranitrate and glyceryl trinitrate in vitro and development of nitrate tolerance.
Topics: Animals; Blood Platelets; Cells, Cultured; Cyclic GMP; Drug Tolerance; Endothelium, Vascular; Hydroxyl Radical; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Spin Trapping; Superoxides; Swine | 1998 |
The effects of stress on homeostasis in JCR-LA-cp rats: the role of nitric oxide.
Topics: Animals; Cyclic GMP; Glutamic Acid; Hippocampus; Homeostasis; Hydrocortisone; Male; Mice; Mice, Inbred ICR; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Obesity; Platelet Aggregation; Rats; Stress, Psychological | 1998 |
Efficacy and rebound phenomenon related to intermittent nitroglycerin therapy for the prevention of nitrate tolerance.
Topics: Administration, Cutaneous; Adult; Cyclic GMP; Drug Tolerance; Female; Forearm; Humans; Male; Middle Aged; Nitrates; Nitroglycerin; Vasodilation; Vasodilator Agents | 1998 |
Viagra: beyond the jokes.
Topics: Cyclic GMP; Drug Interactions; Erectile Dysfunction; Humans; Hypotension; Male; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Risk Factors; Sildenafil Citrate; Sulfones | 1998 |
Exhaled oral and nasal nitric oxide during L-arginine infusion in preeclampsia.
Topics: Adult; Arginine; Blood Pressure; Breath Tests; Cyclic GMP; Female; Heart Rate; Humans; Luminescent Measurements; Mouth; Nitrates; Nitric Oxide; Nose; Pre-Eclampsia; Pregnancy | 1998 |
Role of nitric oxide in cyclosporine A-induced hypertension.
Topics: Animals; Aorta; Arginine; Blood Pressure; Bosentan; Cyclic GMP; Cyclosporine; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hypertension; Immunosuppressive Agents; Male; Nitrates; Nitrites; Olive Oil; Penicillamine; Peptides, Cyclic; Plant Oils; Rats; Rats, Sprague-Dawley; Sulfonamides; Vasoconstriction | 1998 |
Can endothelial function be assessed in vivo by measuring acetylcholine induced changes in nitrate in the forearm in man?
Topics: Acetylcholine; Adult; Cyclic GMP; Endothelium, Vascular; Forearm; Humans; Nitrates; Nitric Oxide | 1998 |
Increased excretion of nitric oxide in exhaled air of patients with chronic renal failure.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Breath Tests; Chi-Square Distribution; Cyclic GMP; Female; Humans; Interferon-gamma; Interleukin-1; Kidney Failure, Chronic; Luminescent Measurements; Male; Middle Aged; Natriuretic Peptide, Brain; Nitrates; Nitric Oxide; Nitrites; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Time Factors | 1999 |
cAMP regulates nitric oxide production and ouabain sensitive Na+, K+-ATPase activity in SH-SY5Y human neuroblastoma cells.
Topics: Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; Epoprostenol; Humans; Isoquinolines; Kinetics; Neuroblastoma; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Ouabain; Sodium-Potassium-Exchanging ATPase; Sulfonamides; Tumor Cells, Cultured | 1998 |
Adaptation of hearts to chronic hypoxia increases tolerance to subsequent ischemia by increased nitric oxide production.
Topics: Aging; Animals; Cyclic GMP; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Heart; Hypoxia; In Vitro Techniques; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rabbits; Shock, Septic; Stress, Physiological; Transcription, Genetic; Ventricular Function, Left; Ventricular Function, Right | 1998 |
Nitric oxide-dependent and independent effects on human platelets treated with peroxynitrite.
Topics: Blood Platelets; Calcium; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Free Radical Scavengers; Guanylate Cyclase; Humans; Immunohistochemistry; Nitrates; Nitric Oxide; Oxadiazoles; Oxidants; Oxyhemoglobins; P-Selectin; Platelet Activation; Quinoxalines | 1998 |
Renoprotective effects of captopril in hypertension induced by nitric oxide synthase inhibition in experimental nephritis.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blood Pressure; Captopril; Cyclic GMP; Enzyme Inhibitors; Female; Glomerulonephritis; Hypertension, Renal; Kidney Tubules; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Organ Size; Rats; Rats, Wistar; Renin | 1999 |
Nonanticoagulant heparin prevents coronary endothelial dysfunction after brief ischemia-reperfusion injury in the dog.
Topics: Animals; Anticoagulants; Blood Coagulation; Coronary Vessels; Cyclic GMP; Dogs; Endothelium, Vascular; Heparin; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide; Nitrites | 1999 |
Pressor hyperreactivity to mental and hand-grip stresses in patients with hypercholesterolemia.
Topics: Baroreflex; Blood Platelets; Blood Pressure; Calcium; Cyclic GMP; Heart Rate; Humans; Hypercholesterolemia; Intracellular Fluid; Lipoproteins, LDL; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Pressoreceptors; Stimulation, Chemical; Stress, Mechanical; Stress, Psychological | 1999 |
Renal vasoconstriction induced by oxidized LDL is inhibited by scavengers of reactive oxygen species and L-arginine.
Topics: Animals; Arginine; Catalase; Cyclic GMP; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Free Radical Scavengers; Glomerular Filtration Rate; Indomethacin; Lipoproteins, LDL; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renal Artery; Superoxide Dismutase; Vasoconstriction | 1999 |
Nitric oxide metabolites, cyclic guanosine 3,5 monophosphate and dimethylarginines during and after uncomplicated pregnancies: a longitudinal study.
Topics: Adult; Arginine; Chromatography, High Pressure Liquid; Creatinine; Cyclic GMP; Enzyme Inhibitors; Ethylenediamines; Female; Free Radical Scavengers; Humans; Immunoenzyme Techniques; Longitudinal Studies; Male; Nitrates; Nitric Oxide; Nitrites; Postpartum Period; Pregnancy; Reference Values; Sulfanilamides; Time Factors | 1999 |
The potent platelet inhibitory effects of S-nitrosated albumin coating of artificial surfaces.
Topics: Animals; Blood Platelets; Blood Vessel Prosthesis; Cattle; Coated Materials, Biocompatible; Collagen; Cyclic GMP; Dogs; Humans; Models, Biological; Nitrates; Nitrosation; Platelet Aggregation; Platelet Aggregation Inhibitors; Serum Albumin, Bovine; Stents; Swine; Video Recording | 1999 |
Phosphorylation of vasodilator-stimulated phosphoprotein: a consequence of nitric oxide- and cGMP-mediated signal transduction in brain capillary endothelial cells and astrocytes.
Topics: Animals; Astrocytes; Blood Proteins; Blood-Brain Barrier; Capillaries; Cell Adhesion Molecules; Cell Communication; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Microfilament Proteins; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 1999 |
Nitric oxide production is low in end-stage renal disease patients on peritoneal dialysis.
Topics: Adult; Aged; Arginine; Citrulline; Creatinine; Cyclic GMP; Female; Humans; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Peritoneal Dialysis | 1999 |
Platelet nitric oxide metabolites in migraine.
Topics: Adult; Blood Platelets; Case-Control Studies; Cyclic GMP; Female; Humans; Male; Migraine Disorders; Nitrates; Nitric Oxide; Nitrites | 1999 |
Role of chloride and inhibitory action of inorganic nitrate on gonadotropin-stimulated steroidogenesis in mouse Leydig tumor cells.
Topics: Aminoquinolines; Androgens; Animals; Calcium Channel Blockers; Chlorides; Chorionic Gonadotropin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; Gonadotropins; Guanylate Cyclase; Isoquinolines; Leydig Cell Tumor; Mice; Nitrates; ortho-Aminobenzoates; Sulfonamides; Testosterone | 1999 |
No detectable NO synthesis from L-arginine or N(G)-hydroxy-L-arginine in fMLP-stimulated human blood neutrophils despite production of nitrite, nitrate, and citrulline from N(G)-hydroxy-L-arginine.
Topics: Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitroarginine | 1999 |
Adaptation to chronic hypoxia confers tolerance to subsequent myocardial ischemia by increased nitric oxide production.
Topics: Adaptation, Physiological; Animals; Chronic Disease; Cyclic GMP; Hypoxia; Myocardial Ischemia; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Rabbits; RNA, Messenger | 1999 |
Cobalt prevents nitric oxide-induced apoptotic motoneuron death in vitro.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Calcium; Cells, Cultured; Cobalt; Cyclic GMP; Electrophysiology; Motor Neurons; Nerve Degeneration; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Rats | 1999 |
Pharmacological comparison between the nitrergic responses produced by intramural nerve stimulation and exogenous NO-donors in rat gastric fundus.
Topics: Animals; Aorta; Cyclic GMP; Electric Stimulation; Gastric Fundus; In Vitro Techniques; Male; Nitrates; Nitric Oxide Donors; Rats; Rats, Wistar | 1999 |
Effects of cyanosis and hypothermic circulatory arrest on lung function in neonatal lambs.
Topics: Animals; Animals, Newborn; Cardiac Output; Cardiopulmonary Bypass; Chronic Disease; Cyanosis; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Heart Arrest, Induced; Lung; Lung Compliance; Nitrates; Nitric Oxide; Nitrites; Pulmonary Diffusing Capacity; Sheep; Vascular Resistance | 1999 |
Role of nitric oxide in regulating neonatal porcine pulmonary artery smooth muscle cell proliferation.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Division; Cells, Cultured; Cyclic GMP; DNA Damage; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Developmental; Immunohistochemistry; Interleukin-1; Lipopolysaccharides; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroso Compounds; Oxygen; Penicillamine; Phosphodiesterase Inhibitors; Pulmonary Artery; Purinones; Swine | 1999 |
Antiplatelet effect of amlodipine: a possible mechanism through a nitric oxide-mediated process.
Topics: Amlodipine; Animals; Blood Platelets; Cyclic AMP; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; In Vitro Techniques; Methemoglobin; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thromboxane B2 | 1999 |
Peroxynitrite is a positive inotropic agent in atrial and ventricular fibres of the frog heart.
Topics: Aminoquinolines; Animals; Atrial Function; Catalase; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Heart Atria; Heart Ventricles; Hydroxyl Radical; Molsidomine; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide Donors; Oxadiazoles; Oxidants; Quinoxalines; Rana esculenta; Sodium; Sodium-Calcium Exchanger; Ventricular Function | 1999 |
[Merits and demerits of nitric oxide].
Topics: Apoptosis; Cell Division; Cyclic GMP; Free Radical Scavengers; Humans; Neoplasms; Nitrates; Nitric Oxide; Superoxides; Vasodilation | 1999 |
Effects of endothelin-1 and nitric oxide on glucokinase activity in isolated rat hepatocytes.
Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Glucokinase; Glucose; Glycogen; Kinetics; Liver; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley | 2000 |
Influence of age on nitric oxide modulatory action on Na(+), K(+)-ATPase activity through cyclic GMP pathway in proximal rat trachea.
Topics: Aging; Animals; Ca(2+) Mg(2+)-ATPase; Cyclic GMP; Enzyme Inhibitors; Indicators and Reagents; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroprusside; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Trachea | 2000 |
Role of adenosine A(2B) receptors in vasodilation of rat pial artery and cerebral blood flow autoregulation.
Topics: Animals; Arteries; Cerebrovascular Circulation; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Flavins; Homeostasis; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Pia Mater; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Thionucleotides; Triazines; Triazoles; Vasodilation | 2000 |
Resistance to endotoxin shock in transgenic mice overexpressing endothelial nitric oxide synthase.
Topics: Animals; Aorta; Blood Pressure; Cyclic GMP; Edema; Female; Granulocytes; Hypotension; Immunity, Innate; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multiple Organ Failure; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Organ Size; Peroxidase; Shock, Septic; Vasodilation | 2000 |
Enhanced renal function in bradykinin B(2) receptor transgenic mice.
Topics: Animals; Cyclic AMP; Cyclic GMP; Humans; Kidney; Kinins; Male; Mice; Mice, Transgenic; Nitrates; Nitrites; Receptor, Bradykinin B2; Receptors, Bradykinin; Renin-Angiotensin System | 2000 |
Dehydroepiandrosterone retards atherosclerosis formation through its conversion to estrogen: the possible role of nitric oxide.
Topics: Acetylcholine; Adjuvants, Immunologic; Animals; Aorta, Thoracic; Aromatase; Arteriosclerosis; Calcimycin; Cholesterol, Dietary; Cyclic GMP; Dehydroepiandrosterone; Diet, Atherogenic; Electrodes; Endothelium, Vascular; Estrogens; Female; Ionophores; Nitrates; Nitric Oxide; Nitrites; Rabbits; Triglycerides; Vasodilation; Vasodilator Agents | 2000 |
Role of endogenous nitric oxide in circadian blood pressure regulation in healthy humans and in patients with hypertension or atherosclerosis.
Topics: Adult; Arterial Occlusive Diseases; Arteriosclerosis; Blood Pressure; Case-Control Studies; Circadian Rhythm; Cyclic GMP; Female; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide | 2000 |
Downregulation of endothelial nitric oxide synthase in rat aorta after prolonged hypoxia in vivo.
Topics: Animals; Aorta; Cyclic GMP; Down-Regulation; Endothelium, Vascular; Hypoxia; Male; Molecular Sequence Data; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Vasodilation | 2000 |
Is asymmetric dimethylarginine a novel marker of atherosclerosis?
Topics: Arginine; Arteriosclerosis; Biomarkers; Carotid Arteries; Chromatography, High Pressure Liquid; Cyclic GMP; Enzyme Inhibitors; Humans; Nitrates; Nitric Oxide Synthase; Regression Analysis; Stereoisomerism; Tunica Intima | 2000 |
Contribution of nitric oxide to the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats.
Topics: Animals; Bile Ducts; Blotting, Western; Cardiomyopathies; Constriction, Pathologic; Cyclic GMP; Cytokines; Enzyme Inhibitors; Heart Ventricles; Immunohistochemistry; Ligation; Liver Cirrhosis, Experimental; Male; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2000 |
Correlation between increased nitric oxide production and markers of endothelial activation in systemic sclerosis: findings with the soluble adhesion molecules E-selectin, intercellular adhesion molecule 1, and vascular cell adhesion molecule 1.
Topics: Aged; Biopsy; Cell Adhesion Molecules; Cyclic GMP; Cytokines; E-Selectin; Endothelium, Vascular; Female; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Receptors, Cytokine; Scleroderma, Systemic; Skin; Solubility; Vascular Cell Adhesion Molecule-1 | 2000 |
Two distinct mechanisms of nitric oxide-mediated neuronal cell death show thiol dependency.
Topics: Acetylcysteine; Animals; Cell Death; Cell Differentiation; Cell Line; Cell Survival; Cyclic GMP; Hydrazines; Molsidomine; Necrosis; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Sulfhydryl Compounds | 2000 |
Physiological concentration of 17beta-estradiol retards the progression of severe atherosclerosis induced by a high-cholesterol diet plus balloon catheter injury: role of NO.
Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Catheterization; Cholesterol; Cholesterol, Dietary; Cyclic GMP; Endothelium, Vascular; Estradiol; Female; Immunohistochemistry; Lipids; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Ovariectomy; Rabbits | 2000 |
Effect of hemodialysis on plasma nitric oxide levels.
Topics: Colorimetry; Cyclic GMP; Female; Follow-Up Studies; Humans; Inflammation Mediators; Kidney Failure, Chronic; Liver Cirrhosis; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Renal Dialysis; Sepsis; Uremia | 2000 |
Effect of antenatal dexamethasone treatment on Ca2+-dependent nitric oxide synthase activity in rat lung.
Topics: Animals; Animals, Newborn; Calcium; Cyclic GMP; Dexamethasone; Female; Fetus; Gestational Age; Lung; Nitrates; Nitric Oxide Synthase; Nitrites; Pregnancy; Rats; Rats, Wistar | 2000 |
Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure.
Topics: Adenoviridae; Animals; Blood Pressure; Blood Urea Nitrogen; Cardiomegaly; Cyclic GMP; Fibrosis; Gene Expression; Genetic Therapy; Humans; Hypertension, Renal; Injections, Intravenous; Kidney Failure, Chronic; Kinins; Male; Nephrectomy; Nitrates; Nitrites; Rats; Rats, Wistar; Renal Circulation; Tissue Kallikreins; Vascular Resistance; Vasodilation; Ventricular Remodeling | 2000 |
Temporal changes of cytokines and nitric oxide products in urine from renal transplant patients.
Topics: Acute Disease; Adult; Creatinine; Cyclic GMP; Cytokines; Female; Follow-Up Studies; Graft Rejection; Humans; Interleukin-10; Interleukin-2; Interleukin-6; Interleukin-8; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Predictive Value of Tests; Time Factors; Tumor Necrosis Factor-alpha; Urinary Tract Infections | 2000 |
Antiplatelet activity of Staphylococcus aureus lipoteichoic acid is mediated through a cyclic AMP pathway.
Topics: Alprostadil; Blood Platelets; Blood Proteins; Calcium Signaling; Collagen; Cyclic AMP; Cyclic GMP; Cytokines; Enzyme Induction; Gram-Positive Bacteria; Humans; Lipopolysaccharides; Molecular Weight; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroglycerin; Phorbol 12,13-Dibutyrate; Phosphorylation; Platelet Aggregation Inhibitors; Protein Kinase C; Protein Processing, Post-Translational; Second Messenger Systems; Shock, Septic; Staphylococcus aureus; Teichoic Acids | 2000 |
The pharmacology of a new nitric oxide donor: B-NOD.
Topics: Animals; Blood Pressure; Cyclic GMP; Heart Rate; Humans; In Vitro Techniques; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Platelet Aggregation Inhibitors; Rabbits; Salicylates | 2000 |
Nitric oxide can differentially modulate striatal neurotransmitter concentrations via soluble guanylate cyclase and peroxynitrite formation.
Topics: Animals; Calcium; Corpus Striatum; Cyclic GMP; Dopamine; Dose-Response Relationship, Drug; Free Radical Scavengers; Guanylate Cyclase; Male; Microdialysis; Neurotransmitter Agents; Nitrates; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar | 2000 |
cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation.
Topics: Animals; Cyclic GMP; Diethylamines; Drug Combinations; Enzyme Inhibitors; Glutathione; In Vitro Techniques; Male; Molsidomine; Myocardial Contraction; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Nucleotides, Cyclic; Oxadiazoles; Oxidation-Reduction; Quinoxalines; Rats; Rats, Wistar; Superoxide Dismutase | 2000 |
Role of inducible nitric-oxide synthase in regulation of whole-cell current in lung epithelial cells.
Topics: Cyclic GMP; Cytokines; Enzyme Activation; Glutathione; Humans; Interferon-gamma; Interleukin-1; Ion Channels; Lung; Membrane Potentials; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroso Compounds; Patch-Clamp Techniques; Recombinant Proteins; S-Nitrosoglutathione; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Aorta; Autoantibodies; Blood Pressure; Calcimycin; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Globins; Hemoglobin, Sickle; Humans; In Vitro Techniques; Lipid Peroxidation; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Papaverine; Vasoconstriction; Vasodilation | 2000 |
Alterations in endogenous nitric oxide production after cardiopulmonary bypass in lambs with normal and increased pulmonary blood flow.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Blotting, Western; Cardiopulmonary Bypass; Cyclic GMP; Disease Models, Animal; Hypertension, Pulmonary; Lung; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pulmonary Artery; Pulmonary Circulation; Sheep; Ultrasonography | 2000 |
Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism.
Topics: Administration, Oral; Animals; Arginine; Body Weight; Cholesterol, Dietary; Collateral Circulation; Cyclic GMP; Endothelium, Vascular; Hindlimb; Hypercholesterolemia; Immunohistochemistry; Ischemia; Laser-Doppler Flowmetry; Lipids; Male; Neovascularization, Physiologic; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2000 |
Effect of VEGF on retinal microvascular endothelial hydraulic conductivity: the role of NO.
Topics: Alkaloids; Aminoquinolines; Animals; Biological Transport; Body Water; Carbazoles; Cattle; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Lymphokines; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Permeability; Retinal Vessels; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia.
Topics: Angiography; Animals; Arginine; Blood Pressure; Body Weight; Collateral Circulation; Cyclic GMP; Disease Models, Animal; Heart Rate; Hindlimb; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Ischemia; Laser-Doppler Flowmetry; Muscle, Skeletal; Neovascularization, Physiologic; Nitrates; Nitrites; Rats; Regional Blood Flow; Time Factors | 2000 |
Paradoxical increase in nitric oxide synthase activity in hypercholesterolaemic rats with impaired renal function and decreased activity of nitric oxide.
Topics: Animals; Arginine; Cholesterol, Dietary; Cyclic GMP; Hypercholesterolemia; Kidney; Male; NADPH Dehydrogenase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Reference Values | 2001 |
An analysis of renal nitric oxide contribution to hyperfiltration in diabetic rats.
Topics: Animals; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glomerular Filtration Rate; Guanylate Cyclase; Kidney; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Arginine; Citrulline; Cyclic GMP; Drug Evaluation; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2000 |
Endothelial dysfunction in salt-sensitive essential hypertension.
Topics: Acetylcholine; Adult; Blood Pressure Monitoring, Ambulatory; Cyclic GMP; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Female; Forearm; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitroprusside; omega-N-Methylarginine; Plethysmography; Regional Blood Flow; Sodium, Dietary; Vasodilation | 2001 |
Role of endothelin B receptors in enhancing endothelium-dependent nitric oxide-mediated vascular relaxation during high salt diet.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Blood Pressure; Cyclic GMP; Endothelin Receptor Antagonists; Endothelium, Vascular; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Phenylephrine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Receptors, Endothelin; Sodium, Dietary; Vasodilation | 2001 |
Oxidative stress and nitric oxide related parameters in type II diabetes mellitus: effects of glycemic control.
Topics: Adult; Aged; Case-Control Studies; Catalase; Cyclic GMP; Diabetes Mellitus, Type 2; Erythrocytes; Female; Glutathione Peroxidase; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Reactive Oxygen Species; Selenium; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Tyrosine | 2001 |
Two possible mechanisms underlying nitrate tolerance in monkey coronary arteries.
Topics: Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic GMP; Drug Interactions; Drug Tolerance; Female; Macaca; Male; Nitrates; Nitric Oxide; Nitroglycerin; Nitroprusside; Vasodilation; Vasodilator Agents | 2001 |
Indices of nitric oxide synthesis and outcome in critically ill patients.
Topics: Aged; APACHE; Biomarkers; Critical Care; Cyclic GMP; Female; Humans; Logistic Models; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Prognosis; Shock, Septic; Survival Rate | 2001 |
L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclic GMP; Endothelins; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydralazine; Hydrazines; Hypertension; In Vitro Techniques; Indomethacin; Male; Methacrylates; Natriuresis; Nitrates; Nitrites; Nitroprusside; Rats; Rats, Inbred Dahl; Renal Artery; Thromboxane A2; Vasoconstriction | 2001 |
Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antineoplastic Agents; Cattle; Cell Adhesion Molecules; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Dextrans; DNA; Drug Synergism; Enzyme Activation; Microfilament Proteins; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Donors; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Purines; Sildenafil Citrate; Sulfones | 2001 |
Endothelium-derived nitric oxide synthase protein expression in ovine placental arteries.
Topics: Amniotic Fluid; Animals; Arteries; Blotting, Western; Crown-Rump Length; Cyclic GMP; Endothelium, Vascular; Female; Fetal Weight; Immunohistochemistry; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Placenta; Pregnancy; Sheep | 2001 |
Peroxynitrite leads to arteriolar smooth muscle cell membrane hyperpolarization and low vasoreactivity in severe shock.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Arginine; Arterioles; Charybdotoxin; Cyclic GMP; Drug Interactions; Female; Free Radical Scavengers; Glyburide; Guanidines; Ion Transport; Male; Membrane Potentials; Mesenteric Arteries; Microscopy, Confocal; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Donors; Norepinephrine; Oxadiazoles; Penicillamine; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Vasodilator Agents | 2000 |
Effects of aging and alterations in dietary sodium intake on total nitric oxide production.
Topics: Adult; Age Factors; Aged; Aging; Blood Pressure; Cyclic GMP; Female; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Sodium, Dietary | 2001 |
Urinary excretion of vasoactive substances in chronic renal failure.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Creatinine; Cyclic GMP; Endothelin-1; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Thromboxane B2; Vasomotor System | 2001 |
Effects of nitric oxide and peroxynitrite on endotoxin-induced leukocyte adhesion to endothelium.
Topics: Animals; Cattle; Cell Adhesion; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Interferon-gamma; Leukocytes; Lipopolysaccharides; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Triazenes | 2001 |
Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.
Topics: Animals; Anions; Baroreflex; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cyclic GMP; Dogs; Male; Myocardial Contraction; Nitrates; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Peptide Fragments; Signal Transduction | 2001 |
Inhibition of neuronal nitric oxide synthase ameliorates renal hyperfiltration in streptozotocin-induced diabetic rat.
Topics: Animals; Cyclic GMP; Diabetes Mellitus, Experimental; Drug Synergism; Enzyme Inhibitors; Glomerular Filtration Rate; Hemodynamics; Indazoles; Infusions, Intravenous; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Rats; Rats, Sprague-Dawley; Renal Plasma Flow; Vascular Resistance | 2001 |
Metabolites of the L-arginine-NO pathway in patients with left-to-right shunt.
Topics: Adolescent; Adult; Age Factors; Arginine; Arteriovenous Shunt, Surgical; Cardiac Catheterization; Case-Control Studies; Child; Child, Preschool; Cyclic GMP; Endocardial Cushion Defects; Female; Heart Septal Defects; Hemodynamics; Humans; Hypertension, Pulmonary; Infant; Male; Nitrates; Nitric Oxide; Pulmonary Circulation | 2001 |
Reciprocal regulation of cyclic GMP content by cyclic GMP-phosphodiesterase and guanylate cyclase in SHR with CsA-induced nephrotoxicity.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Body Weight; Cyclic GMP; Cyclosporine; Dose-Response Relationship, Drug; Guanylate Cyclase; Hypertension; Immunosuppressive Agents; In Vitro Techniques; Kidney; Kidney Diseases; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Perfusion; Pressure; Rats; Rats, Inbred SHR; Vasodilator Agents | 2001 |
High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H(2) receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cel
Topics: Aorta; Apoptosis; Cell Adhesion Molecules; Cells, Cultured; Cyclic GMP; DNA Fragmentation; Endothelium, Vascular; Glucose; Humans; Nitrates; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin; Receptors, Thromboxane A2, Prostaglandin H2; Superoxides; Tyrosine | 2002 |
Blood flow-dependent changes in renal interstitial guanosine 3',5'-cyclic monophosphate in rabbits.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Homeostasis; Kidney Cortex; Kidney Medulla; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Perfusion; Rabbits; Renal Circulation | 2002 |
Antipyretic role of the NO-cGMP pathway in the anteroventral preoptic region of the rat brain.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Fever; Injections, Intraperitoneal; Lipopolysaccharides; Male; Microinjections; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside; omega-N-Methylarginine; Preoptic Area; Rats; Rats, Wistar; Solubility | 2002 |
Lack of critical involvement of endothelial nitric oxide synthase in vascular nitrate tolerance in mice.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroglycerin; Vasodilation; Vasodilator Agents | 2002 |
The role of protein nitration in the inhibition of platelet activation by peroxynitrite.
Topics: Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Nitrates; Nitric Oxide; Peroxynitrous Acid; Phosphorylation; Platelet Activation; Platelet Aggregation; Proteins; Signal Transduction; Thrombin; Time Factors; Tyrosine | 2002 |
DOI, a 5-HT2 receptor agonist, induces renal vasodilation via nitric oxide in anesthetized dogs.
Topics: Anesthesia; Animals; Cyclic GMP; Dogs; Enzyme Inhibitors; Female; Hemodynamics; Indophenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Succinates; Vasodilation | 2002 |
Biochemical markers of the L-arginine-nitric oxide pathway in the aqueous humour in glaucoma patients.
Topics: Aged; Aqueous Humor; Arginine; Biomarkers; Blood Pressure; Cataract; Cyclic GMP; Female; Glaucoma; Humans; Intraocular Pressure; Male; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Signal Transduction | 2002 |
Effects of angiotensin II on the renal interstitial concentrations of NO2/NO3 and cyclic GMP in anesthetized rats.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cyclic GMP; Extracellular Space; Kidney; Male; Microdialysis; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation | 2002 |
Oscillatory shear alters endothelial hydraulic conductivity and nitric oxide levels.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Nitrates; Nitric Oxide; Nitrites; Signal Transduction; Stress, Mechanical; Superoxide Dismutase; Time Factors; Up-Regulation; Water | 2002 |
The anti-platelet agent, ticlopidine, upregulates interleukin-1-Beta-stimulated nitric oxide production in cultured rat vascular smooth muscle cells.
Topics: Animals; Aorta; Cells, Cultured; Cyclic AMP; Cyclic GMP; Interleukin-1; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Ticlopidine; Up-Regulation | 2002 |
Assessment of vascular function in systemic sclerosis: indications of the development of nitrate tolerance as a result of enhanced endothelial nitric oxide production.
Topics: Adult; Aged; Brachial Artery; Cyclic GMP; E-Selectin; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Radial Artery; Regional Blood Flow; Scleroderma, Systemic; Solubility; Vascular Cell Adhesion Molecule-1 | 2002 |
Determination of angiogenesis-regulating properties of NO.
Topics: Animals; Cell Division; Chemotaxis; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Fluorometry; Gelatinases; Microcirculation; Models, Biological; Neovascularization, Physiologic; Nitrates; Nitric Oxide; Nitrites; Rabbits; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2002 |
The ingestion of inorganic nitrate increases gastric S-nitrosothiol levels and inhibits platelet function in humans.
Topics: Administration, Oral; Adolescent; Adult; Collagen; Cyclic GMP; Diet, Vegetarian; Female; Gastric Juice; Humans; Kinetics; Male; Nitrates; Platelet Aggregation; Platelet Function Tests; S-Nitrosothiols; Tyrosine | 2002 |
Human leptin stimulates systemic nitric oxide production in the rat.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Enzyme Inhibitors; Humans; Leptin; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Recombinant Proteins | 2002 |
Effects of Cudrania tricuspidata water extract on blood pressure and renal functions in NO-dependent hypertension.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Blotting, Western; Body Weight; Creatinine; Cyclic GMP; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Plant Bark; Plant Extracts; Rats; Rats, Sprague-Dawley; Sodium | 2002 |
Neuroprotection against ischemic brain injury conferred by a novel nitrate ester.
Topics: Animals; Blood Pressure; Brain; Brain Ischemia; Cyclic GMP; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Infarction, Middle Cerebral Artery; Muscle Relaxation; Muscle, Smooth, Vascular; Neuroprotective Agents; Nitrates; Nitroglycerin; Propane; Rats; Vasodilator Agents | 2002 |
Nitric oxide (NO) pretreatment increases cytokine-induced NO production in cultured rat hepatocytes by suppressing GTP cyclohydrolase I feedback inhibitory protein level and promoting inducible NO synthase dimerization.
Topics: Animals; Biopterins; Blotting, Northern; Blotting, Western; Cells, Cultured; Cyclic GMP; Cytokines; Dimerization; Dose-Response Relationship, Drug; Enzyme Activation; GTP Cyclohydrolase; Hepatocytes; Humans; Male; Muscle, Smooth; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Penicillamine; Protein Binding; Rats; Rats, Sprague-Dawley; Time Factors; Transfection | 2002 |
Nitric oxide production and plasma cyclic guanosine monophosphate in premature infants with respiratory distress syndrome.
Topics: Blood Pressure; Cyclic GMP; Gestational Age; Humans; Hypotension; Infant, Newborn; Infant, Premature; Nitrates; Nitric Oxide; Nitrites; Respiration, Artificial; Respiratory Distress Syndrome, Newborn | 2002 |
Incubation of porcine iris-ciliary bodies to study the mechanisms by which nitric oxide donors lower intraocular pressure.
Topics: Animals; Captopril; Ciliary Body; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Intraocular Pressure; Iris; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitro Compounds; Nitrogen Oxides; Oxadiazoles; Penicillamine; Phosphodiesterase Inhibitors; Purinones; Quinoxalines; Rabbits; S-Nitrosothiols; Spermine; Swine; Time Factors | 2003 |
A nitric oxide-generating beta-blocking agent prevents renal injury in the rat remnant kidney model. Comparative study of two beta-blocking drugs, nipradilol and propranolol.
Topics: Adrenergic beta-Antagonists; Animals; Cyclic GMP; Enzyme Inhibitors; Hypertension; Kidney; Kidney Diseases; Kidney Glomerulus; Male; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Propanolamines; Propranolol; Proteinuria; Rats; Rats, Inbred F344; Renin | 2003 |
Genistein and tyrphostin AG 556 block the action potential shortening in septic shock.
Topics: Action Potentials; Animals; Cyclic GMP; Female; Genistein; Guinea Pigs; Heart; Male; Myocardium; Nitrates; Nitric Oxide; Papillary Muscles; Potassium Channels; Shock, Septic; Tyrphostins | 2002 |
Altered insulin-like growth factor-1 and nitric oxide sensitivities in hypertension contribute to vascular hyperplasia.
Topics: Animals; Aorta, Thoracic; Biomarkers; Blood Pressure; Cell Count; Cell Survival; Cyclic GMP; Diastole; Disease Models, Animal; Hyperplasia; Hypertension; Insulin-Like Growth Factor I; Male; Models, Cardiovascular; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitrates; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole | 2003 |
Exhaled NO and plasma cGMP increase after endotoxin infusion in healthy volunteers.
Topics: Adult; Analysis of Variance; Cyclic GMP; Endotoxins; Humans; Lipopolysaccharides; Luminescent Measurements; Lung; Male; Nitrates; Nitric Oxide; Nitrites; Sepsis | 2003 |
Angiotensin AT2 receptors directly stimulate renal nitric oxide in bradykinin B2-receptor-null mice.
Topics: Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cyclic GMP; Extracellular Space; Imidazoles; Kidney; Mice; Mice, Knockout; Nitrates; Nitric Oxide; Nitrites; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Receptors, Angiotensin; Receptors, Bradykinin; Sodium; Tetrazoles; Valine; Valsartan | 2003 |
Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats.
Topics: Animals; Arteries; Aspirin; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Nitrates; Nitric Oxide Donors; Nitrites; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tail; Thromboxane B2; Time Factors; Vasoconstriction | 2003 |
Alternative splicing of cGMP-dependent protein kinase I in angiotensin-hypertension: novel mechanism for nitrate tolerance in vascular smooth muscle.
Topics: Alternative Splicing; Angiotensins; Animals; Blood Pressure; Cell Separation; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guanylate Cyclase; Hypertension; Isoenzymes; Large-Conductance Calcium-Activated Potassium Channels; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Donors; Patch-Clamp Techniques; Phosphoric Diester Hydrolases; Potassium Channels, Calcium-Activated; Protein Kinase C; Rats; Rats, Inbred WKY; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Soluble Guanylyl Cyclase | 2003 |
Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia.
Topics: Animals; Antioxidants; Blood Vessels; Carotid Arteries; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Hypercholesterolemia; In Vitro Techniques; Lipids; Male; Nitrates; Nitric Oxide; Nitrites; Rabbits; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Tyrosine; Vasodilation | 2003 |
Alternative splicing of cGMP-dependent protein kinase I and nitrate tolerance.
Topics: Alternative Splicing; Angiotensin II; Animals; Basilar Artery; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; DNA, Complementary; Drug Tolerance; Hypertension; Introns; Isoenzymes; Muscle, Smooth, Vascular; Nitrates; Rats; Reproducibility of Results; RNA, Messenger | 2003 |
A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury.
Topics: Acetates; Amines; Animals; Aorta, Thoracic; Behavior, Animal; Cyclic GMP; Cyclohexanecarboxylic Acids; Cyclohexanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intraperitoneal; Lipopolysaccharides; Macrophages; Male; Mice; Muscle, Smooth; Nitrates; Nitric Oxide; Pain; Pain Measurement; PC12 Cells; Peripheral Nerve Injuries; Peripheral Nerves; Rabbits; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Vasodilation | 2004 |
17beta-Oestradiol enhances aortic endothelium function and smooth muscle contraction in male spontaneously hypertensive rats.
Topics: Aging; Animals; Aorta, Thoracic; Culture Techniques; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Estradiol; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitrites; Rats; Rats, Inbred SHR | 2004 |
Garlic supplementation increases peripheral blood flow: a role for interleukin-6?
Topics: Adult; Blood Flow Velocity; Cyclic GMP; Dietary Supplements; Female; Garlic; Humans; Interleukin-6; Leg; Nitrates; Plethysmography; Regional Blood Flow | 2004 |
Uncontrolled hypertension, uncompensated type II diabetes, and smoking have different patterns of vascular dysfunction.
Topics: Adult; Blood Flow Velocity; Cyclic GMP; Diabetes Mellitus, Type 2; Endothelium, Vascular; Humans; Hyperemia; Hypertension; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Smoking; Thromboxane B2; Vasodilation; Vasodilator Agents | 2004 |
Mechanisms of antiplatelet and antithrombotic activity of midazolam in in vitro and in vivo studies.
Topics: Blood Platelets; Cyclic AMP; Cyclic GMP; Electron Spin Resonance Spectroscopy; Fibrinolytic Agents; Fluorescein; Fluorescent Dyes; Free Radicals; Fura-2; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inositol Phosphates; Microcirculation; Midazolam; Nitrates; Phospholipids; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Signal Transduction | 2004 |
Antioxidative treatment reverses imbalances of nitric oxide synthase isoform expression and attenuates tissue-cGMP activation in diabetic rats.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; DNA Primers; Down-Regulation; Immunohistochemistry; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Polymerase Chain Reaction; Protein Isoforms; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfhydryl Compounds; Thioctic Acid; Tissue Distribution; Up-Regulation | 2004 |
Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer.
Topics: Aged; Aged, 80 and over; Amidines; Arachidonic Acid; Benzylamines; Blotting, Northern; Blotting, Western; Cell Division; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Microcirculation; Middle Aged; Models, Biological; Neovascularization, Pathologic; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Platelet Endothelial Cell Adhesion Molecule-1; Prostaglandin-Endoperoxide Synthases; Treatment Outcome; Up-Regulation; Vascular Endothelial Growth Factor A | 2004 |
Chronic l-arginine treatment reduces vascular smooth muscle cell hypertrophy through cell cycle modifications in spontaneously hypertensive rats.
Topics: Animals; Arginine; Carotid Arteries; Cell Cycle; Cell Division; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; G1 Phase; Hypertrophy; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Ploidies; Rats; Rats, Inbred SHR; Time Factors | 2004 |
Chronic endothelin A receptor blockade in lambs with increased pulmonary blood flow and pressure.
Topics: Animals; Aspartic Acid Endopeptidases; Cyclic GMP; Endothelin A Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Female; Hypertension, Pulmonary; Metalloendopeptidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pregnancy; Pulmonary Circulation; Receptor, Endothelin A; Receptor, Endothelin B; Sheep | 2004 |
Influence of intravenously administered leptin on nitric oxide production, renal hemodynamics and renal function in the rat.
Topics: Animals; Blood Pressure; Cardiac Output; Creatinine; Cyclic GMP; Injections, Intravenous; Kidney; Kidney Function Tests; Leptin; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Renal Circulation; Sodium | 2004 |
Endothelial dysfunction in patients with kidney failure and vascular risk factors: acute effects of hemodialysis.
Topics: Adult; Aged; Biomarkers; Blood Pressure; Cyclic GMP; Diastole; Endothelium, Vascular; Female; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitrites; Regional Blood Flow; Renal Circulation; Renal Dialysis; Risk Factors; Statistics as Topic; Systole; Time Factors; Treatment Outcome; Vascular Diseases; Vasodilation | 2004 |
Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies.
Topics: Animals; Blood Platelets; Capillaries; Cell Membrane; Cyclic AMP; Cyclic GMP; Electrophoresis, Capillary; Fluorescein; Fluorescent Dyes; Fura-2; Humans; Immunohistochemistry; In Vitro Techniques; Matrix Metalloproteinase 9; Mice; Nitrates; Phospholipids; Platelet Activation; Platelet Aggregation; Protein Kinase C; Splanchnic Circulation; Thromboxane B2 | 2004 |
Increased expression of regulator of G protein signaling-2 (RGS-2) in Bartter's/Gitelman's syndrome. A role in the control of vascular tone and implication for hypertension.
Topics: Adult; Angiotensin II; Bartter Syndrome; Case-Control Studies; Cohort Studies; Creatinine; Cyclic GMP; Female; Gene Expression; Humans; Hypertension; Middle Aged; Monocytes; Nitrates; Nitrites; RGS Proteins; RNA, Messenger; Vasomotor System | 2004 |
Angiogenesis and vasculogenesis are impaired in the precocious-aging klotho mouse.
Topics: Aging, Premature; Animals; Aorta, Thoracic; Bone Marrow Transplantation; Collateral Circulation; Cyclic GMP; Glucuronidase; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Klotho Proteins; Laser-Doppler Flowmetry; Membrane Proteins; Mice; Mice, Mutant Strains; Models, Animal; Muscle, Skeletal; Neovascularization, Pathologic; Nitrates; Nitric Oxide; Nitrites; Organ Culture Techniques; Pyridines; Ultrasonography | 2004 |
Vasopeptidase inhibitor restores the balance of vasoactive hormones in progressive nephropathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cyclic GMP; Enalapril; Endothelin-1; Heterocyclic Compounds, 3-Ring; Kidney; Kidney Diseases; Male; Nephrectomy; Neprilysin; Nitrates; Nitric Oxide; Nitrites; Proteinuria; Rats; Rats, Sprague-Dawley | 2004 |
Low concentration of oxidized low density lipoprotein suppresses platelet reactivity in vitro: an intracellular study.
Topics: Calcium Signaling; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Lipoproteins, LDL; Nitrates; Platelet Aggregation; Thromboxane B2 | 2004 |
Heart failure increases protein expression and enzymatic activity of heme oxygenase-1 in the lung.
Topics: Animals; Blotting, Western; Cyclic GMP; Heart Failure; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Lung; Models, Animal; Myocardium; Nitrates; p38 Mitogen-Activated Protein Kinases; Proteins; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo.
Topics: Animals; Aorta; Blood Pressure; Blotting, Western; Bone Marrow Cells; Cells, Cultured; Chromones; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Inflammation; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rotenone; Sepsis; Shock, Septic; Time Factors; Tissue Distribution | 2005 |
Nitric oxide-cyclic GMP contributes to abnormal activation of Na+-K+-ATPase in the aorta from rats with endotoxic shock.
Topics: Animals; Aorta; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dose-Response Relationship, Drug; Endotoxemia; Endotoxins; Enzyme Activation; Enzyme Inhibitors; Male; Nitrates; Nitric Oxide; Ouabain; Oxadiazoles; Potassium; Protein Kinase C; Quinoxalines; Rats; Rats, Inbred WKY; Shock, Septic; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Enzyme-independent nitric oxide formation during UVA challenge of human skin: characterization, molecular sources, and mechanisms.
Topics: Animals; Cyclic GMP; Humans; Nitrates; Nitric Oxide; Nitrites; Nitroso Compounds; Rats; Skin; Sulfhydryl Compounds; Ultraviolet Rays | 2005 |
Nitric oxide reverts the resistance to doxorubicin in human colon cancer cells by inhibiting the drug efflux.
Topics: Antibiotics, Antineoplastic; Colonic Neoplasms; Cyclic GMP; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HT29 Cells; Humans; Isoenzymes; Multidrug Resistance-Associated Proteins; Nitrates; Nitric Oxide; Nitric Oxide Synthase; S-Nitroso-N-Acetylpenicillamine | 2005 |
Estrogen ameliorates Nomega-nitro-L-arginine methyl ester-induced blood pressure increment in male spontaneously hypertensive rats: the role of cGMP.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Cyclic GMP; Enzyme Inhibitors; Estradiol; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside; Rats; Rats, Inbred SHR; Vasodilator Agents | 2004 |
[Decrease of nitric oxide (NO)-cGMP-dependent vasodilatation in the vessels of lesser circulation in endothelial dysfunction].
Topics: Animals; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; Hypertension, Pulmonary; Lung; Monocrotaline; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pulmonary Circulation; Rats; Rats, Wistar; Vasodilation | 2005 |
Nitric oxide-nitric oxide synthase regulates key maturational events during chondrocyte terminal differentiation.
Topics: Alkaline Phosphatase; Animals; Blotting, Western; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chick Embryo; Chondrocytes; Collagen Type X; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cysteine; Gene Expression; Growth Plate; Guanylate Cyclase; Immunohistochemistry; Isoenzymes; Luciferases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Promoter Regions, Genetic; Recombinant Fusion Proteins; S-Nitrosoglutathione; S-Nitrosothiols; Sternum; Transfection; Tretinoin; Tyrosine | 2005 |
Kallikrein gene transfer reduces renal fibrosis, hypertrophy, and proliferation in DOCA-salt hypertensive rats.
Topics: Animals; Cell Cycle Proteins; Cell Division; Cyclic GMP; Cyclin-Dependent Kinase Inhibitor p27; Desoxycorticosterone; Disease Models, Animal; Extracellular Matrix; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Gene Transfer Techniques; Genetic Therapy; Hypertension, Renal; Hypertrophy; JNK Mitogen-Activated Protein Kinases; Kallikreins; Male; Nitrates; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Suppressor Proteins | 2005 |
Synthesis and ocular effects of imidazole nitrolic acids.
Topics: Animals; Aqueous Humor; Cyclic GMP; Drug Design; Imidazoles; Iris; Models, Molecular; Molecular Structure; Nitrates; Nitrites; Nitroglycerin; Swine | 2005 |
Correlation of nitric oxide and atrial natriuretic peptide changes with altered cGMP homeostasis in liver cirrhosis.
Topics: Adult; Aged; Ascites; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Guanylate Cyclase; Humans; Liver Cirrhosis; Lymphocytes; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Penicillamine | 2005 |
Dietary arginine supplementation attenuates renal damage after relief of unilateral ureteral obstruction in rats.
Topics: Animals; Arginine; Cyclic GMP; Dietary Supplements; Enzyme Inhibitors; Fibroblasts; Fibrosis; Glomerular Filtration Rate; In Situ Nick-End Labeling; Kidney; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Organ Size; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ureteral Obstruction | 2005 |
Ventricular hypertrophy and arterial hemodynamics following deprivation of nitric oxide in rats.
Topics: Algorithms; Animals; Arteries; Body Weight; Cardiomegaly; Cell Count; Collagen; Cyclic GMP; Electrocardiography; Enzyme Inhibitors; Hemodynamics; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Size; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2005 |
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Arteriosclerosis; Ascorbic Acid; Citrulline; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Diet, Atherogenic; DNA-Binding Proteins; Endothelium, Vascular; ets-Domain Protein Elk-1; Humans; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Proto-Oncogene Proteins; Rabbits; Superoxides; Transcription Factors; Vasodilation; Vitamin E | 2005 |
Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation.
Topics: Animals; Antioxidants; Blood Platelets; Blood Proteins; Carcinogens; Carotenoids; Cyclic AMP; Cyclic GMP; Humans; In Vitro Techniques; Lycopene; Mice; Microcirculation; Nitrates; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Thromboxane B2 | 2005 |
Hemodynamic effects of combined sildenafil and L-arginine during acute pulmonary embolism-induced pulmonary hypertension.
Topics: Acute Disease; Analysis of Variance; Animals; Arginine; Blood Pressure; Cyclic GMP; Dogs; Female; Heart Rate; Hypertension, Pulmonary; Infusions, Intravenous; Male; Nitrates; Nitrites; Piperazines; Pulmonary Artery; Pulmonary Embolism; Purines; Respiration; Sildenafil Citrate; Sulfones; Time Factors; Vasodilator Agents | 2005 |
Opposite relationship between circulating soluble CD14 concentration and endothelial function in diabetic and nondiabetic subjects.
Topics: Brachial Artery; C-Reactive Protein; Cross-Sectional Studies; Cyclic GMP; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Lipopolysaccharide Receptors; Male; Nitrates; Nitrites; Ultrasonography; Vasodilation | 2005 |
Natural compounds derived from foods modulate nitric oxide production and oxidative status in epithelial lung cells.
Topics: Animals; Antioxidants; Biological Products; Blotting, Western; Carbohydrate Sequence; Cell Survival; Cyclic GMP; Cytokines; Epithelial Cells; Food; Lung; Molecular Sequence Data; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; Superoxide Dismutase | 2005 |
Angiotensin II AT2 receptors inhibit proximal tubular Na+-K+-ATPase activity via a NO/cGMP-dependent pathway.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cyclic GMP; Diuresis; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney Tubules, Proximal; Male; Natriuresis; Nitrates; Nitric Oxide; Nitrites; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium-Potassium-Exchanging ATPase | 2006 |
Cyclic GMP-independent mechanisms contribute to the inhibition of platelet adhesion by nitric oxide donor: a role for alpha-actinin nitration.
Topics: Actinin; Blood Platelets; Catechin; Cell Survival; Cells, Cultured; Cyclic GMP; Fibrinogen; Guanylate Cyclase; Humans; Nitrates; Nitric Oxide Donors; Nitroprusside; Platelet Adhesiveness; Solubility; Superoxide Dismutase; Thrombin; Tyrosine | 2006 |
Reduction of myocardial infarct size by tetrahydrobiopterin: possible involvement of mitochondrial KATP channels activation through nitric oxide production.
Topics: Animals; Anti-Arrhythmia Agents; Arginine; Biopterins; Cyclic GMP; Decanoic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxy Acids; Male; Malondialdehyde; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley | 2006 |
Hemodynamic effects of sildenafil interaction with a nitric oxide donor compound in a dog model of acute pulmonary embolism.
Topics: Animals; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dogs; Drug Interactions; Female; Heart Rate; Hemodynamics; Male; Nitrates; Nitric Oxide Donors; Nitrites; Piperazines; Pulmonary Artery; Pulmonary Embolism; Purines; Respiration; Sildenafil Citrate; Sulfones; Time Factors; Vascular Resistance | 2006 |
Vitamin E deficiency accelerates nitrate tolerance via a decrease in cardiac P450 expression and increased oxidative stress.
Topics: alpha-Tocopherol; Animals; Aorta; Cell Adhesion Molecules; Cyclic GMP; Cytochrome P-450 CYP1A2; Down-Regulation; Drug Tolerance; Lipid Peroxidation; Male; Microfilament Proteins; Myocardium; Nitrates; Nitric Oxide; Nitroglycerin; Oxidative Stress; Phosphoproteins; Phosphorylation; Rats; Reactive Oxygen Species; Serine; Vasodilator Agents; Vitamin E; Vitamin E Deficiency | 2006 |
Plasma- and urine concentrations of nitrite/nitrate and cyclic Guanosinemonophosphate in intrauterine growth restricted and preeclamptic pregnancies.
Topics: Birth Weight; Cyclic GMP; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Nitrates; Nitric Oxide; Nitrites; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Prospective Studies | 2006 |
Angiotensin II type 2 receptor agonist directly inhibits proximal tubule sodium pump activity in obese but not in lean Zucker rats.
Topics: Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Imidazoles; Kidney Tubules, Proximal; Male; Nitrates; Nitrites; Obesity; Oligopeptides; Phosphorylation; Pyridines; Rats; Rats, Zucker; Receptor, Angiotensin, Type 2; Sodium-Potassium-Exchanging ATPase; Thinness | 2006 |
Clinical evidence for lead-induced inhibition of nitric oxide formation.
Topics: Adult; Biomarkers; Brazil; Cyclic GMP; Down-Regulation; Environmental Pollutants; Enzyme Inhibitors; Female; Humans; Lead; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites | 2006 |
Synthesis, ocular effects, and nitric oxide donation of imidazole amidoximes.
Topics: Amination; Animals; Cyclic GMP; Eye; Female; Imidazoles; Isomerism; Male; Molecular Structure; Nitrates; Nitric Oxide; Oximes; Rabbits; Structure-Activity Relationship; Swine | 2006 |
Role of probucol on endothelial dysfunction of epicardial coronary arteries associated with left ventricular hypertrophy.
Topics: Angiotensin II; Animals; Antioxidants; Bradykinin; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; Fibrosis; Hypertrophy, Left Ventricular; In Vitro Techniques; Lipid Peroxides; Male; Myocytes, Cardiac; Nitrates; Nitrites; Probucol; Serotonin; Superoxide Dismutase; Swine; Vasodilation | 2006 |
Cyclic GMP release by acute enhanced external counterpulsation.
Topics: Cholesterol, LDL; Counterpulsation; Cyclic GMP; Female; Humans; Male; Middle Aged; Nitrates; Time Factors | 2006 |
Relationship between systemic nitric oxide metabolites and cyclic GMP in healthy male volunteers.
Topics: Adult; Biomarkers; Blood Specimen Collection; Cyclic GMP; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Reference Values | 2006 |
Treatment with hypotensive agents affects the impaired relaxation of the penile corpus cavernosum in hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Carbon Monoxide; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; Hypertension; Indicators and Reagents; Male; Muscle Relaxation; Muscle, Smooth; Nitrates; Nitric Oxide; Nitrites; Penis; Phenylephrine; Rats; Rats, Inbred SHR; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vasoconstrictor Agents | 2006 |
Role of chloride transport proteins in the vasorelaxant action of nitroprusside in isolated rat aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Cations; Chloride Channels; Chlorides; Culture Media; Cyclic GMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitroprusside; Rats; Rats, Wistar; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Vasodilator Agents | 2006 |
Nitric oxide regulates cell survival in purified cultures of avian retinal neurons: involvement of multiple transduction pathways.
Topics: Adenosine; Aminoquinolines; Analysis of Variance; Animals; Cell Survival; Cells, Cultured; Chick Embryo; Cyclic GMP; Cyclic N-Oxides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Penicillamine; Retina; Signal Transduction; Tetrazolium Salts; Thiazoles; Tritium | 2007 |
Effect of renal injury-induced neurogenic hypertension on NO synthase, caveolin-1, AKt, calmodulin and soluble guanylate cyclase expressions in the kidney.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Pressure; Body Weight; Calmodulin; Caveolin 1; Creatinine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Guanylate Cyclase; Hypertension; Isoenzymes; Kidney Cortex; Kidney Diseases; Male; Nitrates; Nitric Oxide Synthase; Phenol; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2007 |
Glutamate-induced activation of nitric oxide synthase is impaired in cerebral cortex in vivo in rats with chronic liver failure.
Topics: Ammonia; Animals; Blotting, Western; Cerebral Cortex; Chronic Disease; Cyclic GMP; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Liver Failure; Male; N-Methylaspartate; Nitrates; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2007 |
Pulmonary vascular changes in piglets with increased pulmonary blood flow and pressure.
Topics: Animals; Animals, Newborn; Aspartic Acid Endopeptidases; Blood Pressure; Cyclic GMP; Endothelin-1; Endothelin-Converting Enzymes; Hypertension, Pulmonary; Immunohistochemistry; Isoenzymes; Lung; Metalloendopeptidases; Nitrates; Nitrites; Pulmonary Artery; Pulmonary Circulation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staining and Labeling; Swine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2007 |
Nitric oxide suppresses preadipocyte differentiation in 3T3-L1 culture.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Death; Cell Differentiation; Culture Media; Cyclic GMP; Gene Expression Regulation; Glycerolphosphate Dehydrogenase; Mice; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; PPAR gamma; Protein Binding; Response Elements; Transcription Factor AP-2; Triglycerides | 2007 |
Essential role of extracellular SOD in reparative neovascularization induced by hindlimb ischemia.
Topics: Animals; Antioxidants; Apoptosis; Bone Marrow Cells; Bone Marrow Transplantation; Cell Differentiation; Cells, Cultured; Cyclic GMP; Cyclic N-Oxides; Endothelium, Vascular; Extracellular Space; Hindlimb; Ischemia; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neovascularization, Physiologic; Nitrates; Nitrites; Reactive Oxygen Species; Spin Labels; Stem Cells; Superoxide Dismutase; Vasculitis | 2007 |
Role of nitric oxide pathway in placental dysfunction following fetal bypass.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Carbon Dioxide; Cardiopulmonary Bypass; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Fetus; Nitrates; Nitric Oxide; Nitrites; Oxygen; Placenta; Placenta Diseases; Postoperative Complications; Pregnancy; Sheep; Signal Transduction | 2007 |
Growth hormone treatment improves markers of systemic nitric oxide bioavailability via insulin-like growth factor-I.
Topics: Aged; Amidohydrolases; Animals; Biomarkers; Cells, Cultured; Cyclic GMP; Dimethylamines; Dinoprost; Endothelial Cells; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Growth Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Mice; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Stem Cells; Vascular Endothelial Growth Factor A | 2007 |
Aminoguanidine produces beneficial haemodynamic effects in a canine model of acute pulmonary thromboembolism.
Topics: Acute Disease; Animals; Blood Pressure; Cyclic GMP; Dogs; Female; Guanidines; Lung; Male; Models, Animal; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Pulmonary Embolism; Vascular Resistance | 2007 |
Inhibitory mechanisms of resveratrol in platelet activation: pivotal roles of p38 MAPK and NO/cyclic GMP.
Topics: Animals; Calcium; Collagen; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Mice; Nitrates; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositols; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Resveratrol; Stilbenes; Thromboxane A2 | 2007 |
11,12-Epoxyeicosatrienoic acid activates the L-arginine/nitric oxide pathway in human platelets.
Topics: 8,11,14-Eicosatrienoic Acid; Adult; Arginine; Biological Transport; Blood Platelets; Calcium Signaling; Collagen; Cyclic GMP; Female; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Tritium | 2008 |
Nitrated cyclic GMP as a new cellular signal.
Topics: Cyclic GMP; Nitrates; Signal Transduction | 2007 |
Influence of soluble guanylate cyclase inhibition on inflammation and motility disturbances in DSS-induced colitis.
Topics: Animals; Colitis; Cyclic GMP; Dextran Sulfate; Disease Models, Animal; Enzyme Inhibitors; Guanylate Cyclase; Inflammation; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Soluble Guanylyl Cyclase | 2008 |
Nitric oxide bioavailability and not production is first altered during the onset of insulin resistance in sucrose-fed rats.
Topics: Animals; Aorta; Biomarkers; Cyclic GMP; Cysteine; Diet; Diet Therapy; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation, Enzymologic; Insulin Resistance; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Sucrose; Sweetening Agents; Tyrosine | 2007 |
Simultaneous assessment of endothelial function, nitric oxide synthase activity, nitric oxide-mediated signaling, and oxidative stress in individuals with and without hypercholesterolemia.
Topics: Adolescent; Adult; Aged; Arginine; Cyclic GMP; Dinoprost; Endothelium, Vascular; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Sex Factors | 2008 |
Hemodynamic effects of urotensin II and its specific receptor antagonist palosuran in cirrhotic rats.
Topics: Administration, Oral; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Hemodynamics; Kidney; Kidney Function Tests; Liver; Liver Cirrhosis, Biliary; Male; Mesenteric Arteries; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Portal Vein; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Urea; Urotensins | 2008 |
Design and synthesis of nitrate esters of aromatic heterocyclic compounds as pharmacological preconditioning agents.
Topics: Animals; Cyclic GMP; Drug Design; Esters; Heterocyclic Compounds; Ischemic Preconditioning; Male; Malondialdehyde; Molecular Structure; Nitrates; Rabbits; Reperfusion Injury; Structure-Activity Relationship | 2008 |
Nitric oxide regulates steroid synthesis by bovine antral granulosa cells in a chemically defined medium.
Topics: Animals; Cattle; Cell Cycle; Cell Survival; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Female; Granulosa Cells; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Progesterone; Quinoxalines | 2009 |
Time-limited hyporesponsiveness to inhaled nitric oxide and pulmonary phosphodiesterase activity in endotoxemic rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Endotoxemia; In Vitro Techniques; Lipopolysaccharides; Lung; Nitrates; Nitric Oxide; Nitrites; Phosphoric Diester Hydrolases; Pulmonary Circulation; Pulmonary Wedge Pressure; Rats; Rats, Sprague-Dawley; Thionucleotides | 2008 |
Oxytocin induces penile erection when injected into the ventral tegmental area of male rats: role of nitric oxide and cyclic GMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hemoglobins; Humans; Male; Microdialysis; Neurotoxins; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitrites; omega-Conotoxin GVIA; Oxytocin; Penile Erection; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2008 |
Endothelin and gelatinases in renal changes following blockade of nitric oxide synthase in hypertensive rats.
Topics: Animals; Azepines; Blood Urea Nitrogen; Collagen; Creatinine; Cyclic GMP; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Gelatinases; Glomerular Filtration Rate; Hypertension; Indoles; Kidney; Matrix Metalloproteinases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Tissue Inhibitor of Metalloproteinase-2 | 2008 |
Endothelial dysfunction in patients with noncomplicated and complicated hypertension.
Topics: Aged; Atherosclerosis; Case-Control Studies; Coronary Artery Disease; Cyclic GMP; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Risk Factors; Vasodilation | 2009 |
The arachidonic acid effect on platelet nitric oxide level.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Blood Platelets; Calcium; Cell Membrane; Cyclic GMP; Enzyme Activation; Humans; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Phosphorylation; Phosphothreonine; Platelet Aggregation; Protein Kinase C; Protein Transport; Superoxides | 2009 |
Hydroxyurea generates nitric oxide in human erythroid cells: mechanisms for gamma-globin gene activation.
Topics: Cyclic GMP; Erythroid Cells; Fetal Hemoglobin; gamma-Globins; Humans; Hydrogen Peroxide; Hydroxyurea; K562 Cells; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Signal Transduction; Stem Cells; Transcription, Genetic; Transcriptional Activation | 2009 |
Analysis of nitric oxide metabolism as a placental or maternal factor underlying the etiology of pre-eclampsia.
Topics: Adult; Aspartic Acid; Case-Control Studies; Cyclic GMP; Female; Gestational Age; Glutamic Acid; Humans; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Placenta; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Elevated plasma concentration of NO and cGMP may be responsible for the decreased platelet aggregation and platelet leukocyte conjugation in platelets hypo-responsive to catecholamines.
Topics: Adenosine Triphosphate; Adult; Asian People; Blood Platelets; Catecholamines; Cyclic AMP; Cyclic GMP; Female; Humans; Leukocyte Common Antigens; Leukocytes; Male; Molsidomine; Nitrates; Nitric Oxide; Nitrites; Platelet Aggregation; Platelet Aggregation Inhibitors; Young Adult | 2009 |
Renal NOS activity, expression, and localization in male and female spontaneously hypertensive rats.
Topics: Animals; Cyclic GMP; Disease Models, Animal; Female; Hypertension; Kidney Cortex; Kidney Medulla; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Inbred SHR; Sex Characteristics | 2010 |
cGMP modulates stem cells differentiation to neurons in brain in vivo.
Topics: Animals; Apoptosis; Brain; Cell Differentiation; Cerebral Cortex; Cyclic GMP; Enzyme Inhibitors; Hippocampus; Neurogenesis; Neurons; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Phosphodiesterase Inhibitors; Piperazines; Prefrontal Cortex; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Stem Cells; Sulfones | 2010 |
Chronic hyperammonemia induces tonic activation of NMDA receptors in cerebellum.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebellum; Cyclic GMP; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hyperammonemia; In Vitro Techniques; Male; Microdialysis; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Phosphorylation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Statistics, Nonparametric; Subcellular Fractions; Threonine | 2010 |
Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.
Topics: Animals; Arginine; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic AMP; Cyclic GMP; Enzyme Activation; Excitatory Amino Acid Agonists; Guanylate Cyclase; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Oncogene Protein v-akt; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2010 |
[Some biochemical parameters in the placenta in discoordinated and powerless labors].
Topics: Adult; Cyclic GMP; Female; Humans; Nitrates; Nitrites; Obstetric Labor Complications; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy | 2009 |
Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice.
Topics: Animals; Aorta; Apolipoproteins E; Cells, Cultured; Cilostazol; Cyclic GMP; Endothelin-1; Endothelium, Vascular; Humans; Hypercholesterolemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Cerebral Artery; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Phosphodiesterase Inhibitors; Tetrazoles; Vasoconstriction; Vasodilation | 2010 |
Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of bis selenide in the mouse tail suspension test.
Topics: Administration, Oral; Animals; Antidepressive Agents; Arginine; Behavior, Animal; Brain; Cyclic GMP; Hindlimb Suspension; Male; Mice; Nitrates; Nitric Oxide; Nitrites; Organoselenium Compounds; Signal Transduction; Swimming | 2010 |
Inorganic nitrate for blood pressure lowering?
Topics: Blood Pressure; Cyclic GMP; Heart Rate; Humans; Hypertension; Nitrates; Nitric Oxide; Potassium Compounds; Risk Factors | 2011 |
Changes in nitric oxide, cGMP, and nitrotyrosine concentrations over skin along the meridians in obese subjects.
Topics: Acupuncture Points; Adult; Cyclic GMP; Cyclic N-Oxides; Female; Humans; Imidazoles; Male; Nitrates; Nitric Oxide; Nitrites; Obesity; Skin; Tyrosine | 2011 |
iNOS expression in vascular resident macrophages contributes to circulatory dysfunction of splanchnic vascular smooth muscle contractions in portal hypertensive rats.
Topics: Animals; Calcium; Cyclic GMP; Hypertension, Portal; Lipopolysaccharides; Liver Cirrhosis; Macrophages; Male; Mesenteric Arteries; Monocytes; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type II; Nitroprusside; Portal Vein; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Vasodilator Agents | 2011 |
Atorvastatin worsens left ventricular diastolic dysfunction and endothelial dysfunction of epicardial coronary arteries in normocholesterolemic porcine with left ventricular hypertrophy.
Topics: Angiotensin II; Animals; Aorta; Atorvastatin; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Echocardiography; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Male; Nitrates; Nitrites; Pyrroles; Random Allocation; Swine; Vasodilation; Ventricular Dysfunction, Left | 2011 |
Nitric oxide synthase activity in the abdominal aorta of rats is decreased after 4 weeks of simulated microgravity.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Arginine; Cyclic GMP; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilation; Weightlessness Simulation | 2011 |
Hydrogen sulfide as a cryogenic mediator of hypoxia-induced anapyrexia.
Topics: Aminooxyacetic Acid; Analysis of Variance; Animals; Body Temperature; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Sulfide; Hypothermia; Hypoxia; Male; Microinjections; Nitrates; Nitric Oxide Synthase; Nitrites; Preoptic Area; Rats; Rats, Wistar; Sulfides; Third Ventricle; Time Factors | 2012 |
Decreased leukocyte recruitment by inorganic nitrate and nitrite in microvascular inflammation and NSAID-induced intestinal injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Cell Movement; Cells, Cultured; Chemokine CXCL2; Cyclic GMP; Diclofenac; Dietary Supplements; Endothelial Cells; Gene Expression; Humans; Inflammation; Intercellular Adhesion Molecule-1; Intestine, Small; Leukocyte Count; Male; Mice; Mice, Inbred C57BL; Microvessels; Mouthwashes; Neutrophil Infiltration; Nitrates; Nitrites; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Staphylococcus aureus | 2012 |
Antihypertensive and antioxidant effects of a single daily dose of sodium nitrite in a model of renovascular hypertension.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Catalase; Cyclic GMP; Disease Models, Animal; Hemoglobins; Hypertension, Renovascular; Male; Nitrates; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Sodium Nitrite; Superoxide Dismutase | 2012 |
Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase.
Topics: Allopurinol; Animal Feed; Animals; Antibiotics, Antineoplastic; Bleomycin; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Pulmonary Circulation; Ventricular Pressure; Xanthine Dehydrogenase | 2012 |
Novel diallyldisulfide analogs ameliorate cardiovascular remodeling in rats with L-NAME-induced hypertension.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Calcium; Cyclic GMP; Disulfides; Eating; Gene Expression Regulation, Enzymologic; Hypertension; Male; Muscle, Smooth, Vascular; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Vasoconstriction | 2012 |
Dietary nitrate supplementation improves revascularization in chronic ischemia.
Topics: Animal Feed; Animals; Bone Marrow Transplantation; Cell Movement; Chronic Disease; Cyclic GMP; Dietary Supplements; Disease Models, Animal; Femoral Artery; Green Fluorescent Proteins; Hindlimb; Ischemia; Laser-Doppler Flowmetry; Ligation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myoblasts; Nitrates; Nitric Oxide; Nitrites; Regeneration; Regional Blood Flow; S-Nitrosothiols | 2012 |
Inhibiting inducible nitric oxide synthase with rutin reduces renal ischemia/reperfusion injury.
Topics: Animals; Biomarkers; Cyclic GMP; Enzyme Inhibitors; Immunohistochemistry; Infusions, Parenteral; Kidney; Lysine; Male; Nephrectomy; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Protective Agents; Rats; Rats, Wistar; Reperfusion Injury; Rutin; Tyrosine | 2013 |
Acute obstructive jaundice and chronic cirrhosis protect against the adverse renal effects of pneumoperitoneum: role of nitric oxide.
Topics: Acute Disease; Animals; Cyclic GMP; Glomerular Filtration Rate; Jaundice, Obstructive; Liver Cirrhosis; Male; Nitrates; Nitrites; Pneumoperitoneum, Artificial; Rats; Rats, Sprague-Dawley; Renal Plasma Flow; Sodium; Urination | 2013 |
Nitrated cyclic GMP modulates guard cell signaling in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Calcium; Chromatography, Liquid; Cyclic ADP-Ribose; Cyclic GMP; Darkness; Light; Mixed Function Oxygenases; Mutation; Nitrates; Nitric Oxide; Plant Stomata; Reactive Oxygen Species; Signal Transduction; Tandem Mass Spectrometry | 2013 |
Activation of cGMP/protein kinase G pathway in postconditioned myocardium depends on reduced oxidative stress and preserved endothelial nitric oxide synthase coupling.
Topics: Animals; Biopterins; Cell Death; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Ischemic Postconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Time Factors; Tyrosine | 2013 |
Circadian phase-dependent effect of nitric oxide on L-type voltage-gated calcium channels in avian cone photoreceptors.
Topics: Animals; Blotting, Western; Calcium Channels, L-Type; Chick Embryo; Circadian Rhythm; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Immunoenzyme Techniques; In Vitro Techniques; MAP Kinase Signaling System; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oncogene Protein v-akt; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Retinal Cone Photoreceptor Cells; RNA, Small Interfering; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Transfection | 2013 |
Clopidogrel results in favourable changes in nitric oxide metabolism in patients undergoing percutaneous coronary intervention.
Topics: Biomarkers; Clopidogrel; Coronary Artery Disease; Cyclic GMP; Humans; Nitrates; Nitric Oxide; Nitrites; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Time Factors; Treatment Outcome; Vasodilation; Wales | 2014 |
Mechanisms underlying the vascular and hypotensive actions of the labdane ent-3-acetoxy-labda-8(17),13-dien-15-oic acid.
Topics: Animals; Aorta; Blood Pressure; Calcium; Calcium Chloride; Cyclic AMP; Cyclic GMP; Diterpenes; In Vitro Techniques; Intracellular Space; Male; Nitrates; Nitric Oxide; Phenylephrine; Rats; Rats, Wistar; Serotonin; Time Factors; Vasoconstriction; Vasodilator Agents | 2014 |
Role of inorganic nitrate and nitrite in driving nitric oxide-cGMP-mediated inhibition of platelet aggregation in vitro and in vivo.
Topics: Animals; Blood Platelets; Cyclic GMP; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphodiesterase 5 Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Second Messenger Systems; Sodium Nitrite; Time Factors | 2014 |
The effect of peroxynitrite decomposition catalyst MnTBAP on aldehyde dehydrogenase-2 nitration by organic nitrates: role in nitrate tolerance.
Topics: Aldehyde Dehydrogenase; Animals; Aorta; Blood Platelets; Cyclic GMP; Drug Tolerance; Endothelium, Vascular; Humans; Hypotension; Isosorbide Dinitrate; Male; Metalloporphyrins; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; Platelet Aggregation; Rats; Thrombin; Tyrosine; Vasodilator Agents | 2014 |
Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway.
Topics: Adipocytes, Brown; Adipocytes, White; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar | 2015 |
Effects of hyperbaric oxygen on nitric oxide generation in humans.
Topics: Adult; Arginine; Breath Tests; Citrulline; Cyclic GMP; Humans; Hyperbaric Oxygenation; Nitrates; Nitric Oxide; Nitrites; Oxygen; Saliva; Tongue; Young Adult | 2015 |
Membrane-anchored MucR mediates nitrate-dependent regulation of alginate production in Pseudomonas aeruginosa.
Topics: Alginates; Cyclic GMP; Gene Deletion; Gene Expression Regulation, Bacterial; Glucuronic Acid; Hexuronic Acids; Membrane Proteins; Mutagenesis, Site-Directed; Nitrates; Pseudomonas aeruginosa | 2015 |
Involvement in Denitrification is Beneficial to the Biofilm Lifestyle of Comamonas testosteroni: A Mechanistic Study and Its Environmental Implications.
Topics: Aerobiosis; Biofilms; Comamonas testosteroni; Cyclic GMP; Denitrification; Gene Expression Regulation, Bacterial; Nitrates; Polymerase Chain Reaction; Sequence Analysis, RNA; Wastewater | 2015 |
Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism.
Topics: Animal Feed; Animals; Cyclic GMP; Diet; Dose-Response Relationship, Drug; Fatty Acids; Male; Muscle, Skeletal; Nitrates; Nitric Oxide; Organelle Biogenesis; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptors; Rats; Rats, Wistar | 2015 |
Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia.
Topics: Arginine; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Cyclic GMP; Female; Homeostasis; Humans; Hypotension; Infant; Infant, Newborn; Male; Nitrates; Nitric Oxide; Nitrites; Peritoneal Dialysis | 2016 |
Sodium nitrite exerts an antihypertensive effect and improves endothelial function through activation of eNOS in the SHR.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Aorta; Arterial Pressure; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; HSP90 Heat-Shock Proteins; Hypertension; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Phosphorylation; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Sodium Nitrite | 2016 |
Alternative hematological and vascular adaptive responses to high-altitude hypoxia in East African highlanders.
Topics: Adaptation, Physiological; Africa, Eastern; Altitude; Altitude Sickness; Blood Pressure; Blood Vessels; Cyclic GMP; Demography; Diastole; Ethnicity; Hemoglobins; Humans; Hypoxia; Nitrates; Oxyhemoglobins | 2017 |
Inhibition of the Expression of Inducible NO Synthase by Neuroactive Amino Acid Derivatives Phenibut and Glufimet In Vitro and Ex Vivo.
Topics: Animals; Animals, Outbred Strains; Anti-Inflammatory Agents; Cyclic GMP; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Injections, Intraperitoneal; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Primary Cell Culture | 2017 |
A novel purine analogue bearing nitrate ester prevents platelet activation by ROCK activity inhibition.
Topics: Cyclic GMP; Esters; Humans; Nitrates; Nitric Oxide; Platelet Activation; Platelet Aggregation; Protein Kinase Inhibitors; Purines; Receptors, Purinergic P1; Receptors, Purinergic P2; rho-Associated Kinases; Signal Transduction | 2019 |
Novel Barbiturate-Nitrate Compounds Inhibit the Upregulation of Matrix Metalloproteinase-9 Gene Expression in Intestinal Inflammation through a cGMP-Mediated Pathway.
Topics: Anti-Inflammatory Agents; Barbiturates; Caco-2 Cells; Cyclic GMP; Humans; Inflammatory Bowel Diseases; Matrix Metalloproteinase 9; Nitrates; Nitric Oxide; Signal Transduction; Up-Regulation | 2020 |
Adoptive transfer of placental ischemia-stimulated natural killer cells causes a preeclampsia-like phenotype in pregnant rats.
Topics: Adoptive Transfer; Animals; Cyclic GMP; Cytokines; Female; Fetal Growth Retardation; Ischemia; Killer Cells, Natural; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Phenotype; Placenta; Pre-Eclampsia; Pregnancy; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2021 |
Reduction of alternative electron acceptors drives biofilm formation in Shewanella algae.
Topics: Bacterial Proteins; Biofilms; Cyclic GMP; Dimethyl Sulfoxide; Electrons; Gene Expression Regulation, Bacterial; Mutation; Nitrates; Oxidation-Reduction; Oxidoreductases; Shewanella; Signal Transduction | 2021 |
Nitrate Is an Environmental Cue in the Gut for Salmonella enterica Serovar Typhimurium Biofilm Dispersal through Curli Repression and Flagellum Activation via Cyclic-di-GMP Signaling.
Topics: Bacterial Proteins; Biofilms; Cues; Cyclic GMP; Flagella; Gene Expression Regulation, Bacterial; Humans; Inflammation; Nitrates; Salmonella enterica; Salmonella typhimurium; Serogroup | 2021 |