nitrates and citrulline

nitrates has been researched along with citrulline in 122 studies

Research

Studies (122)

TimeframeStudies, this research(%)All Research%
pre-19909 (7.38)18.7374
1990's43 (35.25)18.2507
2000's35 (28.69)29.6817
2010's28 (22.95)24.3611
2020's7 (5.74)2.80

Authors

AuthorsStudies
Hishikawa, K; Kato, R; Nakaki, T; Saruta, T; Suzuki, H1
Brosnan, JT; Wu, GY1
Billiar, TR; Curran, RD; Hoffman, RA; Langrehr, JM; Simmons, RL1
Adams, LB; Hibbs, JB; Krahenbuhl, JL; Taintor, RR1
Hibbs, JB; Taintor, RR; Vavrin, Z1
Marletta, MA; Tayeh, MA1
Billiar, TR; Curran, RD; Hofmann, K; Simmons, RL; West, MA1
Billiar, TR; Curran, RD; Ferrari, FK; Simmons, RL; Stuehr, DJ1
Iyengar, R; Marletta, MA; Stuehr, DJ1
Bentz, BG; Billiar, TR; Curran, RD; Simmons, RL; Stuehr, DJ; West, MA1
Amber, IJ; Hibbs, JB; Taintor, RR; Vavrin, Z1
Hiort, U; Kating, H1
Cañedo, L; Martuscelli, J; Mora, J1
Acimovic, S; Andel, H; Függer, R; Längle, F; Mühlbacher, F; Roth, R; Steininger, R; Winkler, S1
Chen, PY; Sanders, PW1
Hevel, JM; Marletta, MA1
Kunz, D; Mühl, H; Pfeilschifter, J1
Absood, A; Berisha, HI; Pakbaz, H; Said, SI1
Fehsel, K; Kolb-Bachofen, V; Kröncke, KD; Sommer, A; Suschek, C1
Marletta, MA; Pufahl, RA; Wishnok, JS1
Bucher, B; Busse, R; Hecker, M; Schott, C; Stoclet, JC1
Conte, A; Ottaviani, E1
Deliconstantinos, G; Stavrides, JC; Villiotou, V2
Bosia, A; Bussolino, F; Costamagna, C; Deharo, E; Gabrielli, G; Gautret, P; Ghigo, D; Ginsburg, H; Giribaldi, G; Pescarmona, G; Todde, R; Ulliers, D1
Enczmann, J; Fehsel, K; Kolb-Bachofen, V; Rothe, H; Suschek, C1
Fischer, WN; Frommer, WB; Hirner, B; Hummel, S; Kwart, M; Ninnemann, O1
Ludwig, RA1
Flynn, NE; Wu, G1
Bloch, KD; Castillo, L; Kurrek, MM; Tannenbaum, SR; Zapol, WM1
al-Shekhlee, A; Bongiorno, PB; Canteros, G; Gold, PW; Licinio, J; McCann, SM; Rettori, V; Wong, ML1
Aihara, T; Ikeda, Y; Koyama, Y; Kusano, T; Muto, Y; Shiraishi, M1
Chou, SM; Komai, K; Wang, HS1
Ajami, AM; Beaumier, L; Castillo, L; Young, VR1
Castaneda, C; Crim, MC; Dawson-Hughes, B; Lammi-Keefe, C; Prior, RL; Rosen, CJ; Spindler, AA1
Pasquet, JP; Ullrich, V; Zou, MH1
Chaudhuri, G; Ignarro, LJ; Pervin, S; Rogers, NE; Singh, R1
Higa, T; Hiroyasu, S; Kusano, T; Miyaguni, T; Muto, Y; Nagahama, M; Okuhama, Y; Shiraishi, M; Tomori, H1
Dubey, RK; Fink, D; Imthurn, B; Keller, PJ; Lauper, U; Macas, E; Rosselli, M; Rosselli, MA1
Barbul, A; Schäffer, MR; Tantry, U; van Wesep, RA1
Barthlen, W; Beger, HG; Brückner, UB; Marzinzig, E; Marzinzig, M; Morris, SM; Nussler, AK; Nussler, NC; Stadler, J1
Chouaib, S; Dugas, B; Dugas, N; Kolb, JP; Salvucci, O1
Houdijk, AP; Prins, HA; Teerlink, T; Thijs, LG; van Lambalgen, AA; van Leeuwen, PA; Wiezer, MJ1
Houdijk, AP; Rijnsburger, ER; Teerlink, T; van Leeuwen, PA; Visser, JJ1
Baylis, C; Schmidt, RJ; Sorkin, MI; Tracy, TS; Yokota, S1
Feelisch, M; Frey, A; Fröhlich, LG; Hofmann, H; Kotsonis, P; Reif, A; Schmidt, HH; Wink, DA1
Weiske, J; Wiesner, A1
Eliasson, MJ; Ferrante, RJ; Huang, Z; Molliver, ME; Moskowitz, MA; Sasamata, M; Snyder, SH1
Holm, P; Kankaanranta, H; Knowles, RG; Moilanen, E; Oja, SS1
Baylis, C; Domico, J; Engels, K; Samsell, LS; Schmidt, RJ; Sorkin, MI; Tracy, TS; Yokota, S1
Almeida, A; Bolaños, JP; Heales, SJ; Medina, JM; Vega-Agapito, V1
Aziz, A; Eissa, S; Khalifa, A1
Jan, KY; Liu, F1
Boulmerka, A; D'Alessio, P; D'Anna, R; Dugas, B; Geromin, D; Kolb, JP; Marconi, A; Marsac, C; Zadeh, MS1
Chen, PF; Wu, KK2
Cobben, DC; Dejong, CH; Deutz, NE; Hallemeesch, MM; Soeters, PB1
Gourdon, I; Guérin, MC; Roch, P; Torreilles, J1
Fraser, T; Li, M; Turner, SW; Wang, J; Wen, C; Whitworth, JA1
Gauthier, S; Law, A; Quirion, R1
Bayne, E; Duckworth, LJ; Freeman, B; Kissoon, N; Lima, JJ; Sandler, E; Sullivan, KJ; Sylvester, JE1
Deutz, NE; Hallemeesch, MM; Soeters, PB1
Bergamini, S; Daneri, F; Iannone, A; Rota, C; Tomasi, A; Virgili, F1
Cedergren, J; Forslund, T; Skogh, T; Sundqvist, T1
Leza, JC; Lizasoaín, I; Manzanares, J; Molina, JA; Moro, MA; Oliva, JM; Ortiz, S; Pérez, S; Urigüen, L1
Deutz, NE; Luiking, YC1
Cuzzocrea, S; Ischiropoulos, H; Salvemini, D1
Endo, T; Hara, S; Kuriiwa, F; Kurosaki, K; Mukai, T1
Franke, J; Gasslander, T; Sandstrom, P; Sundqvist, T; Svanvik, J1
Abu-Soud, HM; Diamond, MP; Galijasevic, S; Saed, GM1
Acosta, F; Díaz, R; Ellis, AE; Gómez, V; Padilla, D; Real, F; Ruiz de Galarreta, CM1
Selley, ML1
Antunes-Rodrigues, J; Cunha, FQ; Elias, LL; Giusti-Paiva, A; Gomes, DA; Reis, WL; Ventura, RR1
Arranz, C; Balaszczuk, AM; Costa, MA; Elesgaray, R; Loria, A2
Alving, K; Bergström, J; Marteus, H; Mavropoulos, A; Palm, JP; Ulfgren, AK1
Boudko, D; Dahlgren, RL; Lovell, P; Moroz, LL; Sweedler, JV1
Bachmann, C; Boulat, O; Carrozzo, R; Dionisi-Vici, C; Emma, F; Mannucci, L; Markert, M; Rizzoni, G1
Govindasamy, C; Nadiger, HA; Sirajudeen, KN; Swamy, M; Zakaria, AZ1
Fukatsu, A; Funami, J; Hayashi, T; Ignarro, LJ; Iguchi, A; Juliet, PA; Matsui-Hirai, H; Miyazaki, A1
Boeckx, WD; Booi, D; Buurman, WA; Debats, IB; Deutz, NE; van der Hulst, RR1
Barges-Coll, J; Boll, MC; Castro, E; Montes, S; Pérez-Neri, I; Ríos, C; Soto-Hernández, JL1
Gross, SS; Weissman, BA1
Hovorková, P; Klaschka, J; Kozmiková, I; Kristofiková, Z; Majer, E; Rícný, J; Rípová, D; Zach, P1
Bannink, M; Eggermont, AM; Fekkes, D; Hengeveld, MW; Kruit, WH; Sleijfer, S; Stoter, G; van der Holt, B; Van Gool, AR1
Ananthakrishnan, M; Barr, FE; Cunningham, G; Fike, CD; Kaplowitz, M; Magarik, J; Smith, HA; Summar, ML; Zhang, Y1
Chandran, G; Sirajudeen, KN; Swamy, M1
Felipo, V; Llansola, M1
McCarty, MF1
Brown, M; Duckworth, L; Froyen, M; Gauger, C; Kissoon, N; Murphy, S; Sandler, E; Sullivan, KJ1
Bombardieri, M; Hendler, A; Houri-Haddad, Y; Hughes, FJ; Mulli, TK; Nissim, A; Perrett, D; Weiss, EI1
de Hoon, JN; Depré, M; Van der Schueren, BJ; Van Hecken, A; Verbesselt, R; Verbrugge, FH1
Bluck, LJ; Feelisch, M; Siervo, M; Stephan, BC1
Fung, HL; Mohan, S; Shin, S; Wu, CC1
Bourdon, A; Darmaun, D; Des Robert, C; Legrand, A; Piloquet, H; Rougé, C; Rozé, JC; Vodovar, M; Voyer, M1
Bescós, R; Pons, A; Sureda, A; Tur, JA1
Chapman, MS; Clark, SA; Davulcu, O1
Busanello, EN; Grings, M; Leipnitz, G; Moura, AP; Tonin, AM; Viegas, CM; Wajner, M; Zanatta, A1
Chien, SJ; Huang, CF; Huang, LT; Kuo, HC; Lin, KM; Lin, YJ; Tain, YL1
Borniquel, S; Carlström, M; Hezel, M; Huang, L; Kishikawa, H; Liu, M; Lundberg, JO; Peleli, M; Persson, AE; Weitzberg, E; Yang, T; Zollbrecht, C1
Awad, AS; Cooper, TK; Gao, T; Morris, SM; You, H1
Eriksson, K; Larsson, AC; Lindholm, P; Nihlén, C; Schiffer, T; Uusijärvi, J; Weitzberg, E1
Andre, T; McKinley-Barnard, S; Morita, M; Willoughby, DS1
Bhargava, K; Bhaumik, G; Gangwar, A; Himashree, G; Padhy, G; Sethy, NK; Sharma, M; Singh, K1
Aranda Fraustro, A; Guarner Lans, V; Iturriaga Hernández, AV; Pérez-Torres, I; Soto, ME; Velázquez Espejel, R; Zuñiga-Muñoz, A1
Alsop, P; Hauton, D1
Akopova, O; Gavenauskas, B; Kolchinskaya, L; Korkach, Y; Kotsiuruba, A; Mankovska, I; Nosar, V; Sagach, V; Serebrovska, Z1
Doutreleau, S; Le Roux-Mallouf, T; Verges, S; Vibert, F1
Bluck, L; Cox, SE; Kamuhabwa, A; Makani, J; Marealle, AI; Minzi, O; Prentice, AM; Sasi, P; Siervo, M; Soka, D; Wassel, S1
Bollenbach, A; Bonati, U; Fischer, D; Hafner, P; Hanff, E; Kayacelebi, AA; Tsikas, D1
Bollenbach, A; Tsikas, D1
Cao, X; Jin, Q; Ma, Q; Wu, L; Zhang, J; Zhong, C; Zhu, C1
Belaidi, E; Besset, D; Corne, C; Doutreleau, S; Larribaut, J; Laurent, J; Le Roux-Mallouf, T; Marillier, M; Verges, S1
Doutreleau, S; Halimaoui, I; Le Roux-Mallouf, T; Pelen, F; Vallejo, A; Verges, S2
Keith, DS; Persky, AM; Ryan, ED; Schwartz, TA; Smith-Ryan, AE; Stoner, L; Trexler, ET1
Gonzalez, AM; Trexler, ET1
Azizi, S; Ebrahimi-Mameghani, M; Karamzad, N; Mahdavi, R; Mobasseri, M1
Blake, HT; Buckley, JD; Coates, AM; d'Unienville, NMA; Hill, AM; Nelson, MJ1
Clifford, T; Craighead, DH; Rossman, MJ; Seals, DR; Shannon, OM1
Beckmann, B; Blau, LS; Dimina, L; Finkel, A; Jantz, M; Lützow, M; Maassen, N; Mariotti, F; Röhrig, MA; Shushakov, V; Thorns, A; Tsikas, D1
Gonzalez, AM; Hoffman, JR; Pinzone, AG; Townsend, JR1

Reviews

9 review(s) available for nitrates and citrulline

ArticleYear
Transporters for nitrogenous compounds in plants.
    Plant molecular biology, 1994, Volume: 26, Issue:5

    Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Carrier Proteins; Cell Compartmentation; Citrulline; Nitrates; Peptides; Plant Proteins; Plants; Quaternary Ammonium Compounds; Substrate Specificity

1994
Isotopic investigation of nitric oxide metabolism in disease.
    Current opinion in clinical nutrition and metabolic care, 2003, Volume: 6, Issue:1

    Topics: Arginine; Biomarkers; Citrulline; Humans; Isotope Labeling; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes

2003
Roles of nitric oxide and superoxide in inflammation.
    Methods in molecular biology (Clifton, N.J.), 2003, Volume: 225

    Topics: 2-Naphthylamine; Animals; Arginine; Blotting, Western; Capillary Permeability; Chemotaxis, Leukocyte; Citrulline; Fluorescent Dyes; Fluorometry; Inflammation; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Rats; Superoxides; Tyrosine

2003
Measurement of in vivo nitric oxide synthesis in humans using stable isotopic methods: a systematic review.
    Free radical biology & medicine, 2011, Aug-15, Volume: 51, Issue:4

    Topics: Age Factors; Arginine; Arteries; Cardiovascular Diseases; Citrulline; Clinical Laboratory Techniques; Humans; Nitrates; Nitric Oxide; Oxygen; Radioisotopes; Reproducibility of Results; Vasodilation

2011
The effect of nitric-oxide-related supplements on human performance.
    Sports medicine (Auckland, N.Z.), 2012, Feb-01, Volume: 42, Issue:2

    Topics: Arginine; Citrulline; Dietary Supplements; Endothelium-Dependent Relaxing Factors; Exercise Tolerance; Humans; Malates; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Sodium Nitrite; Task Performance and Analysis

2012
Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature.
    Journal of strength and conditioning research, 2020, Volume: 34, Issue:5

    Topics: Amino Acids, Branched-Chain; Antioxidants; Arginine; Biomarkers; Citrulline; Dietary Supplements; Drug Therapy, Combination; Exercise; Humans; Malates; Muscle, Skeletal; Nitrates

2020
Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials.
    Journal of the International Society of Sports Nutrition, 2021, Dec-29, Volume: 18, Issue:1

    Topics: Arginine; Citrulline; Exercise Tolerance; Female; Food; Food Analysis; Humans; Male; Nitrates; Nitric Oxide; Physical Endurance; Polyphenols; Randomized Controlled Trials as Topic

2021
Nitric oxide, aging and aerobic exercise: Sedentary individuals to Master's athletes.
    Nitric oxide : biology and chemistry, 2022, 08-01, Volume: 125-126

    Topics: Aged; Aging; Athletes; Citrulline; Dietary Supplements; Exercise; Humans; Nitrates; Nitric Oxide

2022
Supplementation with Nitric Oxide Precursors for Strength Performance: A Review of the Current Literature.
    Nutrients, 2023, Jan-28, Volume: 15, Issue:3

    Topics: Arginine; Citrulline; Dietary Supplements; Humans; Muscle, Skeletal; Nitrates; Nitric Oxide; Nitric Oxide Synthase

2023

Trials

13 trial(s) available for nitrates and citrulline

ArticleYear
Indices of activity of the nitric oxide system in hemodialysis patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 34, Issue:2

    Topics: Arginine; Blood Pressure; Citrulline; Cyclic GMP; Diet; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Renal Dialysis; Second Messenger Systems

1999
Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:7

    Topics: Acute Chest Syndrome; Acute Disease; Administration, Oral; Adolescent; Anemia, Sickle Cell; Arginine; Aspartic Acid; Breath Tests; Child; Citrulline; Female; Glutamic Acid; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Young Adult

2010
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:11

    Topics: Area Under Curve; Arginine; Biomarkers; Citrulline; Cyclic GMP; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites

2010
Urinary citrulline in very low birth weight preterm infants receiving intravenous nutrition.
    The British journal of nutrition, 2012, Volume: 108, Issue:7

    Topics: Biomarkers; Child Development; Citrulline; Energy Intake; France; Gastrointestinal Tract; Humans; Infant Nutritional Physiological Phenomena; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Male; Multivariate Analysis; Nitrates; Nitrites; Parenteral Nutrition; Parenteral Nutrition, Total; Pilot Projects

2012
Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis.
    Journal of the International Society of Sports Nutrition, 2015, Volume: 12

    Topics: Adolescent; Adult; Animals; Arginine; Biomarkers; Body Mass Index; Citrulline; Cyclic GMP; Dietary Supplements; Double-Blind Method; Glutathione; Healthy Volunteers; Human Umbilical Vein Endothelial Cells; Humans; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Resistance Training; Young Adult

2015
Effect of acute nitrate and citrulline supplementation on muscle microvascular response to ischemia-reperfusion in healthy humans.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2017, Volume: 42, Issue:9

    Topics: Adult; Beta vulgaris; Citrulline; Dietary Supplements; Female; Fruit and Vegetable Juices; Hemoglobins; Humans; Hyperemia; Leg; Male; Microvessels; Muscle, Skeletal; Nitrates; Oxyhemoglobins; Plant Roots; Reperfusion Injury; Single-Blind Method; Spectroscopy, Near-Infrared; Vascular Resistance; Young Adult

2017
Effects of single and combined metformin and L-citrulline supplementation on L-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications.
    Amino acids, 2018, Volume: 50, Issue:10

    Topics: Adult; Amidinotransferases; Arginine; Citrulline; Creatinine; Dietary Supplements; Female; Glycine; Guanidinoacetate N-Methyltransferase; Homoarginine; Humans; Male; Metformin; Middle Aged; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nitrates; Nitric Oxide Synthase Type I; Treatment Outcome; Young Adult

2018
Effects of acute nitric oxide precursor intake on peripheral and central fatigue during knee extensions in healthy men.
    Experimental physiology, 2019, Volume: 104, Issue:7

    Topics: Adult; Beta vulgaris; Citrulline; Cross-Over Studies; Double-Blind Method; Humans; Isometric Contraction; Male; Muscle Fatigue; Nitrates; Nitric Oxide; Quadriceps Muscle; Transcranial Magnetic Stimulation; Young Adult

2019
Effect of chronic nitrate and citrulline supplementation on vascular function and exercise performance in older individuals.
    Aging, 2019, 05-29, Volume: 11, Issue:10

    Topics: Aged; Athletic Performance; Blood Vessels; Citrulline; Diagnostic Techniques, Cardiovascular; Dietary Supplements; Double-Blind Method; Female; Hemodynamics; Humans; Hypercapnia; Hypoxia; Male; Middle Aged; Nitrates

2019
Effects of Citrulline Malate and Beetroot Juice Supplementation on Blood Flow, Energy Metabolism, and Performance During Maximum Effort Leg Extension Exercise.
    Journal of strength and conditioning research, 2019, Volume: 33, Issue:9

    Topics: Adolescent; Adult; Beta vulgaris; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Energy Metabolism; Exercise; Femoral Artery; Fruit and Vegetable Juices; Humans; Malates; Male; Nitrates; Nitrites; Performance-Enhancing Substances; Plant Roots; Quadriceps Muscle; Regional Blood Flow; Ultrasonography; Young Adult

2019
Oxidative stress and nitrate/nitrite (NOx) status following citrulline supplementation in type 2 diabetes: a randomised, double-blind, placebo-controlled trial.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2021, Volume: 34, Issue:1

    Topics: Adult; Antioxidants; Blood Glucose; Citrulline; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Glutathione Peroxidase; Humans; Iran; Male; Malondialdehyde; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Superoxide Dismutase

2021
Synergetic Effect of NO Precursor Supplementation and Exercise Training.
    Medicine and science in sports and exercise, 2020, Volume: 52, Issue:11

    Topics: Adaptation, Physiological; Adult; Citrulline; Dietary Supplements; Double-Blind Method; Exercise; Exercise Test; Female; Healthy Volunteers; Humans; Male; Muscle Strength; Nitrates; Nitric Oxide; Physical Endurance; Vasodilation; Young Adult

2020
Short-Term Supplementation of Sodium Nitrate vs. Sodium Chloride Increases Homoarginine Synthesis in Young Men Independent of Exercise.
    International journal of molecular sciences, 2022, Sep-13, Volume: 23, Issue:18

    Topics: Arginine; Citrulline; Creatine; Creatinine; Dietary Supplements; Glutamates; Glutamine; Glycine; Homoarginine; Humans; Lysine; Male; Malondialdehyde; Methyltransferases; Nitrates; Nitrites; Ornithine; Phenylalanine; Sarcosine; Sodium Chloride; Tryptophan; Tyrosine

2022

Other Studies

100 other study(ies) available for nitrates and citrulline

ArticleYear
L-arginine as an antihypertensive agent.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12

    Topics: Antihypertensive Agents; Arginine; Blood Pressure; Cardiac Output; Citrulline; Cushing Syndrome; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Injections, Intravenous; Nitrates; Nitrites

1992
Macrophages can convert citrulline into arginine.
    The Biochemical journal, 1992, Jan-01, Volume: 281 ( Pt 1)

    Topics: Animals; Arginine; Carbon Radioisotopes; Cells, Cultured; Citrulline; Kinetics; Lipopolysaccharides; Macrophages; Male; Nitrates; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains

1992
Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Oct-01, Volume: 145, Issue:7

    Topics: Animals; Arginine; Citrulline; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Immune Tolerance; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Macrophages; Mice; Nitrates; omega-N-Methylarginine; Phytohemagglutinins; Rats; T-Lymphocytes; T-Lymphocytes, Cytotoxic

1990
Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Apr-01, Volume: 144, Issue:7

    Topics: Animals; Arginine; Citrulline; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitrates; Nitrites; Nitrogen Oxides; omega-N-Methylarginine; Toxoplasma

1990
Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite.
    Science (New York, N.Y.), 1987, Jan-23, Volume: 235, Issue:4787

    Topics: Ammonia; Animals; Cells, Cultured; Citrulline; Cytotoxicity, Immunologic; Homoarginine; Hydrolases; Macrophage Activation; Macrophages; Mice; Nitrates; Nitrites

1987
Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor.
    The Journal of biological chemistry, 1989, Nov-25, Volume: 264, Issue:33

    Topics: Animals; Arginine; Biopterins; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Kinetics; Macrophages; NADP; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction

1989
Kupffer cell cytotoxicity to hepatocytes in coculture requires L-arginine.
    Archives of surgery (Chicago, Ill. : 1960), 1989, Volume: 124, Issue:12

    Topics: Animals; Arginine; Aspartate Aminotransferases; Cell Survival; Cells, Cultured; Citrulline; Infections; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; omega-N-Methylarginine; Protein Biosynthesis; Rats; Rats, Inbred Strains

1989
Evidence that activation of Kupffer cells results in production of L-arginine metabolites that release cell-associated iron and inhibit hepatocyte protein synthesis.
    Surgery, 1989, Volume: 106, Issue:2

    Topics: Animals; Arginine; Citrulline; Culture Media; Iron; Kupffer Cells; Lipopolysaccharides; Liver; Male; Nitrates; Nitrites; Protein Biosynthesis; Proteins; Rats

1989
Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:18

    Topics: Arginine; Citrulline; Humans; Hydrogen Peroxide; Macrophage Activation; Macrophages; Morpholines; Nitrates; Nitrites; Nitrosamines; Superoxides

1987
An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro.
    The Journal of experimental medicine, 1989, Apr-01, Volume: 169, Issue:4

    Topics: Animals; Arginine; Citrulline; In Vitro Techniques; Kupffer Cells; Lipopolysaccharides; Liver; Nitrates; Nitrites; Protein Biosynthesis; Rats; Rats, Inbred Strains

1989
Cytokines induce an L-arginine-dependent effector system in nonmacrophage cells.
    Journal of leukocyte biology, 1988, Volume: 44, Issue:1

    Topics: Animals; Arginine; Biological Products; Citrulline; Cytokines; Humans; Lipopolysaccharides; Mammary Neoplasms, Experimental; Nitrates; Nitrites; Tumor Cells, Cultured; Urea

1988
[Arginase and urease synthesis in Micrococcus denitrificans Beij. under aerobic and anaerobic culture conditions].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1969, Volume: 24, Issue:7

    Topics: Ammonium Chloride; Arginase; Arginine; Citrulline; Culture Media; Micrococcus; Nitrates; Ornithine; Oxygen; Urea; Urease

1969
Catabolism of L-arginine in Neurospora crassa.
    National Cancer Institute monograph, 1967, Volume: 27

    Topics: Arginase; Arginine; Carbon Isotopes; Citrulline; Membrane Transport Proteins; Neurospora; Nitrates; Ornithine; Quaternary Ammonium Compounds; Transaminases; Urease

1967
L-arginine deficiency and hemodynamic changes as a result of arginase efflux following orthotopic liver transplantation.
    Transplantation proceedings, 1995, Volume: 27, Issue:5

    Topics: Adult; Arginase; Arginine; Blood Pressure; Citrulline; Diastole; Female; Humans; Liver Transplantation; Male; Monitoring, Intraoperative; Nitrates; Nitrites; Ornithine; Pulmonary Wedge Pressure; Reperfusion

1995
Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:6

    Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Dexamethasone; Disease Models, Animal; Homoarginine; Hypertension; Insulin; Male; Nitrates; Nitric Oxide; Ornithine; Rats; Rats, Inbred Strains

1993
Nitric-oxide synthase assays.
    Methods in enzymology, 1994, Volume: 233

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chromatography, Ion Exchange; Citrulline; Dithiothreitol; Hemoglobins; Indicators and Reagents; Mammals; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Pterins; Sensitivity and Specificity; Spectrophotometry

1994
Expression of nitric oxide synthase in rat glomerular mesangial cells mediated by cyclic AMP.
    British journal of pharmacology, 1994, Volume: 112, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Oxidoreductases; Animals; Antimetabolites; Arginine; Blotting, Northern; Cells, Cultured; Citrulline; Cyclic AMP; Cytosol; Enzyme Activation; Glomerular Mesangium; Interleukin-1; Kinetics; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation

1994
Nitric oxide as a mediator of oxidant lung injury due to paraquat.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-02, Volume: 91, Issue:16

    Topics: Amino Acid Oxidoreductases; Animals; Calcium; Citrulline; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidants; Paraquat; Perfusion; Respiration

1994
Primary cultures of rat islet capillary endothelial cells. Constitutive and cytokine-inducible macrophagelike nitric oxide synthases are expressed and activities regulated by glucose concentration.
    The American journal of pathology, 1994, Volume: 145, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Base Sequence; Capillaries; Cells, Cultured; Citrulline; Cytokines; Endothelium, Vascular; Glucose; Islets of Langerhans; Male; Molecular Sequence Data; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Phenotype; Rats; Rats, Wistar

1994
Hydrogen peroxide-supported oxidation of NG-hydroxy-L-arginine by nitric oxide synthase.
    Biochemistry, 1995, Feb-14, Volume: 34, Issue:6

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Benzene Derivatives; Cell Line; Citrulline; Hydrogen Peroxide; Kinetics; Macrophages; Mice; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; Oxygen; Peroxides; tert-Butylhydroperoxide

1995
Increase in serum NG-hydroxy-L-arginine in rats treated with bacterial lipopolysaccharide.
    European journal of pharmacology, 1995, Feb-24, Volume: 275, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Escherichia coli; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Stereoisomerism

1995
Nitric oxide synthase activity in molluscan hemocytes.
    FEBS letters, 1995, May-29, Volume: 365, Issue:2-3

    Topics: Amino Acid Oxidoreductases; Animals; Antibodies; Arginine; Citrulline; Hemocytes; Kinetics; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rabbits; Snails

1995
Modulation of particulate nitric oxide synthase activity and peroxynitrite synthesis in cholesterol enriched endothelial cell membranes.
    Biochemical pharmacology, 1995, May-26, Volume: 49, Issue:11

    Topics: Amino Acid Oxidoreductases; Animals; Cattle; Cell Membrane; Cholesterol; Citrulline; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Manganese; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Superoxides

1995
Erythrocyte stages of Plasmodium falciparum exhibit a high nitric oxide synthase (NOS) activity and release an NOS-inducing soluble factor.
    The Journal of experimental medicine, 1995, Sep-01, Volume: 182, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biological Factors; Canavanine; Cell Adhesion; Cells, Cultured; Citrulline; Culture Media, Conditioned; Cyclic GMP; Endothelium, Vascular; Enzyme Induction; Erythrocytes; Host-Parasite Interactions; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Plasmodium; Plasmodium falciparum; Protozoan Proteins; Species Specificity; Umbilical Veins

1995
Induction of a macrophage-like nitric oxide synthase in cultured rat aortic endothelial cells. IL-1 beta-mediated induction regulated by tumor necrosis factor-alpha and IFN-gamma.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Sep-15, Volume: 151, Issue:6

    Topics: Amino Acid Oxidoreductases; Animals; Aorta; Base Sequence; Cells, Cultured; Citrulline; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Induction; In Vitro Techniques; Interferon-gamma; Interleukin-1; Macrophages; Male; Molecular Sequence Data; Nitrates; Nitric Oxide Synthase; Oligodeoxyribonucleotides; Rats; Rats, Inbred Lew; Recombinant Proteins; Tumor Necrosis Factor-alpha

1993
Arabidopsis chloroplasts dissimilate L-arginine and L-citrulline for use as N source.
    Plant physiology, 1993, Volume: 101, Issue:2

    Topics: Adenosine Triphosphate; Arabidopsis; Arginine; Bicarbonates; Cell Compartmentation; Chloroplasts; Citrulline; Hydrolases; Models, Biological; Nitrates; Nitrogen; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases (Carboxyl Group Acceptor); Quaternary Ammonium Compounds

1993
The activation of the arginine-citrulline cycle in macrophages from the spontaneously diabetic BB rat.
    The Biochemical journal, 1993, Aug-15, Volume: 294 ( Pt 1)

    Topics: Animals; Arginine; Citrulline; Diabetes Mellitus, Type 1; Macrophages; Male; Nitrates; Peritoneal Cavity; Rats; Rats, Inbred BB

1993
Inhaled nitric oxide does not alter endotoxin-induced nitric oxide synthase activity during rat lung perfusion.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 79, Issue:4

    Topics: Administration, Inhalation; Animals; Arginine; Citrulline; Endotoxins; Feedback; In Vitro Techniques; Lung; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Perfusion; Rats; Rats, Sprague-Dawley

1995
Inducible nitric oxide synthase gene expression in the brain during systemic inflammation.
    Nature medicine, 1996, Volume: 2, Issue:5

    Topics: Animals; Brain; Citrulline; Enzyme Induction; Gene Expression Regulation, Enzymologic; Hypothalamus, Middle; In Situ Hybridization; Male; Nitrates; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Systemic Inflammatory Response Syndrome; Tissue Distribution

1996
Protection against hepatic ischemia/reperfusion injury by exogenous L-arginine.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Animals; Arginine; Citrulline; Cyclic GMP; Liver; Liver Circulation; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury

1996
Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study.
    Journal of chemical neuroanatomy, 1996, Volume: 10, Issue:3-4

    Topics: Amyotrophic Lateral Sclerosis; Citrulline; Cyclic GMP; Cytoplasm; Humans; Immunohistochemistry; Motor Neurons; Neurofilament Proteins; Nitrates; Nitric Oxide; Nitrogen; Oxidation-Reduction; Superoxide Dismutase; Tyrosine

1996
Whole body nitric oxide synthesis in healthy men determined from [15N] arginine-to-[15N]citrulline labeling.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Oct-15, Volume: 93, Issue:21

    Topics: Adult; Arginine; Citrulline; Eating; Fasting; Humans; Isotope Labeling; Male; Models, Biological; Nitrates; Nitric Oxide; Nitrites; Nitrogen Isotopes; Time Factors

1996
Conditions altering plasma concentrations of urea cycle and other amino acids in elderly human subjects.
    Journal of the American College of Nutrition, 1996, Volume: 15, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids; Arginine; Citrulline; Cohort Studies; Data Collection; Dietary Proteins; Eating; Energy Intake; Fasting; Female; Humans; Middle Aged; Nitrates; Ornithine; Postmenopause; Regression Analysis; Time Factors

1996
Increase of particulate nitric oxide synthase activity and peroxynitrite synthesis in UVB-irradiated keratinocyte membranes.
    The Biochemical journal, 1996, Dec-15, Volume: 320 ( Pt 3)

    Topics: Allosteric Regulation; Calcium; Calmodulin; Cell Membrane; Citrulline; Cyclic GMP; Fluorescence Polarization; Guanylate Cyclase; Humans; Keratinocytes; Kinetics; Microsomes; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species; Temperature; Ultraviolet Rays

1996
Peroxynitrite inhibition of nitric oxide synthases.
    Biochimie, 1996, Volume: 78, Issue:8-9

    Topics: Animals; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Glutathione; Isoenzymes; Mice; Nitrates; Nitric Oxide Synthase; Swine

1996
Evidence for the presence of an unusual nitric oxide- and citrulline-producing enzyme in rat kidney.
    Biochemical and biophysical research communications, 1997, Mar-27, Volume: 232, Issue:3

    Topics: Animals; Calcium; Calmodulin; Citrulline; Enzyme Inhibitors; Female; Guinea Pigs; Isoenzymes; Isothiuronium; Kidney; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pregnancy; Rats; Rats, Sprague-Dawley; Sepharose

1997
Role of exogenous L-arginine in hepatic ischemia-reperfusion injury.
    The Journal of surgical research, 1997, Volume: 69, Issue:2

    Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Citrulline; Cyclic GMP; Female; Hemodynamics; Liver; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Reperfusion Injury; Swine; Time Factors

1997
Identification of nitric oxide synthase in human and bovine oviduct.
    Molecular human reproduction, 1996, Volume: 2, Issue:8

    Topics: Animals; Arginine; Cattle; Cells, Cultured; Citrulline; Epithelial Cells; Epithelium; Fallopian Tubes; Female; Humans; In Vitro Techniques; NADPH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitrites

1996
Nitric oxide metabolism in wounds.
    The Journal of surgical research, 1997, Jul-15, Volume: 71, Issue:1

    Topics: Animals; Citrulline; Enzyme Induction; Macrophages; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Nitrites; Ornithine; Skin; Time Factors; Wound Healing

1997
Improved methods to measure end products of nitric oxide in biological fluids: nitrite, nitrate, and S-nitrosothiols.
    Nitric oxide : biology and chemistry, 1997, Volume: 1, Issue:2

    Topics: Body Fluids; Chromatography, Ion Exchange; Citrulline; Humans; Mercaptoethanol; Nitrates; Nitric Oxide; Nitrites; Nitroso Compounds; S-Nitrosothiols; Tumor Cells, Cultured

1997
The induction of nitric oxide by interleukin-12 and tumor necrosis factor-alpha in human natural killer cells: relationship with the regulation of lytic activity.
    Blood, 1998, Sep-15, Volume: 92, Issue:6

    Topics: Adjuvants, Immunologic; Antibodies; Cells, Cultured; Citrulline; Cytotoxicity, Immunologic; Drug Synergism; Enzyme Induction; Granzymes; Guanidines; Humans; Interferon-gamma; Interleukin-12; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lymphocyte Activation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitroprusside; Serine Endopeptidases; Tumor Necrosis Factor-alpha

1998
Reduced arginine plasma levels are the drive for arginine production by the kidney in the rat.
    Shock (Augusta, Ga.), 1999, Volume: 11, Issue:3

    Topics: Animals; Arginase; Arginine; Blood Chemical Analysis; Cattle; Citrulline; Digestive System; Endotoxemia; Kidney; Liver; Male; Nitrates; Nitrites; Ornithine; Rats; Rats, Wistar; Regional Blood Flow

1999
Dietary glutamine supplementation reduces plasma nitrate levels in rats.
    Clinical nutrition (Edinburgh, Scotland), 1998, Volume: 17, Issue:1

    Topics: Animals; Arginine; Citrulline; Dietary Supplements; Glutamine; Kinetics; Male; Nitrates; Rats; Rats, Inbred F344

1998
Nitric oxide production is low in end-stage renal disease patients on peritoneal dialysis.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Adult; Aged; Arginine; Citrulline; Creatinine; Cyclic GMP; Female; Humans; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Peritoneal Dialysis

1999
Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activity.
    The Biochemical journal, 1999, Jun-15, Volume: 340 ( Pt 3)

    Topics: Animals; Arginine; Cerebellum; Citrulline; Feedback; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Inhibitory Concentration 50; Kinetics; Methemoglobin; Methionine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrogen; Reactive Oxygen Species; Superoxide Dismutase; Swine

1999
Stimulation of NO synthase activity in the immune-competent lepidopteran Estigmene acraea hemocyte line.
    Nitric oxide : biology and chemistry, 1999, Volume: 3, Issue:2

    Topics: Animals; Arginine; Cell Line; Citrulline; Enzyme Activation; Enzyme Inhibitors; Hemocytes; Immunocompetence; Kinetics; Lepidoptera; NADP; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Superoxide Dismutase

1999
Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jul-15, Volume: 19, Issue:14

    Topics: Animals; Brain; Cerebral Infarction; Citrulline; Corpus Striatum; Enzyme Activation; Functional Laterality; Immunohistochemistry; Injections, Intraperitoneal; Ischemic Attack, Transient; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Microinjections; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidants; Tyrosine

1999
No detectable NO synthesis from L-arginine or N(G)-hydroxy-L-arginine in fMLP-stimulated human blood neutrophils despite production of nitrite, nitrate, and citrulline from N(G)-hydroxy-L-arginine.
    Journal of leukocyte biology, 1999, Volume: 66, Issue:1

    Topics: Arginine; Cells, Cultured; Citrulline; Cyclic GMP; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Nitroarginine

1999
Peroxynitrite anion stimulates arginine release from cultured rat astrocytes.
    Journal of neurochemistry, 1999, Volume: 73, Issue:4

    Topics: Animals; Animals, Newborn; Arginine; Astrocytes; Cells, Cultured; Citrulline; Glutamic Acid; Hydrogen Peroxide; Kinetics; Lysine; Nitrates; Nitric Oxide Donors; Oxidants; Rats; Rats, Wistar; Serine

1999
Determination of cytosolic citrulline and nitrate as indicators of nitric oxide in bladder cancer: possible association with basic fibroblast growth factor.
    Clinical biochemistry, 1999, Volume: 32, Issue:8

    Topics: Biomarkers, Tumor; Chromatography, High Pressure Liquid; Citrulline; Cytosol; Fibroblast Growth Factor 2; Humans; Immunoenzyme Techniques; Nitrates; Nitric Oxide; Reference Values; Schistosomiasis; Urinary Bladder; Urinary Bladder Neoplasms

1999
DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells.
    Free radical biology & medicine, 2000, Jan-01, Volume: 28, Issue:1

    Topics: Amitrole; Animals; Antioxidants; Aorta; Arsenites; Bacterial Proteins; Cadmium Chloride; Catalase; Cattle; Cells, Cultured; Chromans; Citrulline; Ditiocarb; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Endothelium, Vascular; Enzyme Inhibitors; Escherichia coli Proteins; Free Radical Scavengers; Hydrogen Peroxide; Molsidomine; Mutagens; N-Glycosyl Hydrolases; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Onium Compounds; Phenanthrolines; Reactive Oxygen Species; Sodium Compounds; Sodium Selenite; Superoxide Dismutase; Superoxides; Thiomalates; Thiourea; Uric Acid

2000
Regulation of ICAM-1/CD54 expression on human endothelial cells by hydrogen peroxide involves inducible NO synthase.
    Journal of leukocyte biology, 2000, Volume: 67, Issue:3

    Topics: Cells, Cultured; Citrulline; Drug Synergism; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-1; Isoenzymes; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2000
Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer.
    The Journal of biological chemistry, 2000, Apr-28, Volume: 275, Issue:17

    Topics: Amino Acid Sequence; Animals; Calcium; Calmodulin; Catalysis; Cell Line; Citrulline; Dose-Response Relationship, Drug; Electron Transport; Escherichia coli; Humans; Insecta; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis; NADH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Protein Binding; Sequence Homology, Amino Acid

2000
Renal amino acid metabolism during endotoxemia in the rat.
    The Journal of surgical research, 2000, Volume: 92, Issue:2

    Topics: Amino Acids; Animals; Carbon Dioxide; Citrulline; Endotoxemia; Endotoxins; Escherichia coli; Glutamine; Kidney; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Oxygen; Oxygen Consumption; p-Aminohippuric Acid; Rats; Rats, Wistar; Renal Circulation

2000
Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis.
    Nitric oxide : biology and chemistry, 2001, Volume: 5, Issue:1

    Topics: Animals; Arginine; Bivalvia; Citrulline; Enzyme Inhibitors; Hemocytes; Latex; Luminescent Measurements; Microspheres; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Phagocytosis; Superoxide Dismutase; Superoxides

2001
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
    Blood pressure, 2000, Volume: 9, Issue:5

    Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Arginine; Citrulline; Cyclic GMP; Drug Evaluation; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Stereoisomerism

2000
Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity.
    British journal of pharmacology, 2001, Volume: 133, Issue:7

    Topics: Amyloid beta-Peptides; Animals; Antioxidants; Benzoates; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Citrulline; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imidazoles; Isoenzymes; Lysine; Neuroprotective Agents; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxidants; Peptide Fragments; Rats; Rats, Sprague-Dawley; Thiourea; Time Factors

2001
Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome.
    American journal of respiratory and critical care medicine, 2001, Dec-15, Volume: 164, Issue:12

    Topics: Acute Disease; Adolescent; Anemia, Sickle Cell; Arginine; Breath Tests; Child; Citrulline; Forced Expiratory Volume; Genotype; Humans; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Polymorphism, Genetic; Syndrome; Trinucleotide Repeats; Vital Capacity

2001
Renal arginine and protein synthesis are increased during early endotoxemia in mice.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:2

    Topics: Amino Acids; Ammonia; Animals; Arginine; Citrulline; Endotoxemia; Female; Kidney; Lipopolysaccharides; Mice; Nitrates; Nitric Oxide; Protein Biosynthesis; Urea

2002
N-Acetylcysteine negatively modulates nitric oxide production in endotoxin-treated rats through inhibition of NF-kappaB activation.
    Antioxidants & redox signaling, 2002, Volume: 4, Issue:1

    Topics: Acetylcysteine; Animals; Citrulline; DNA; Endotoxins; Enzyme Activation; Free Radical Scavengers; Lipopolysaccharides; Male; NF-kappa B; Nitrates; Nitric Oxide; Nitrites; Protein Binding; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2002
Inducible nitric oxide synthase is expressed in synovial fluid granulocytes.
    Clinical and experimental immunology, 2002, Volume: 130, Issue:1

    Topics: Adult; Aged; Arginine; Arthritis, Rheumatoid; Autoimmune Diseases; Blood Cells; Chromatography, High Pressure Liquid; Citrulline; Colorimetry; Enzyme Induction; Exudates and Transudates; Female; Granulocytes; Humans; Knee; Male; Membrane Proteins; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Organ Specificity; Synovial Fluid

2002
Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites are increased in dementia with Lewy bodies.
    Neuroscience letters, 2002, Nov-22, Volume: 333, Issue:2

    Topics: Aged; Arginine; Citrulline; Female; Humans; Lewy Body Disease; Male; Nitrates; Nitrites

2002
Characterization of suppression of nitric oxide production by carbon monoxide poisoning in the striatum of free-moving rats, as determined by in vivo brain microdialysis.
    Brain research, 2003, Jul-25, Volume: 979, Issue:1-2

    Topics: Animals; Arginine; Carbon Monoxide Poisoning; Citrulline; Corpus Striatum; Extracellular Space; Isomerism; Male; Microdialysis; Movement; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley

2003
Depletion of serum L-arginine in patients with acute pancreatitis.
    Pancreas, 2003, Volume: 27, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Alcoholism; Amylases; Arginine; C-Reactive Protein; Cholecystitis, Acute; Citrulline; Female; Gallstones; Humans; Male; Middle Aged; Nitrates; Nitrites; Pancreatitis; Pancreatitis, Alcoholic; Recurrence; Time Factors

2003
Structural elements contribute to the calcium/calmodulin dependence on enzyme activation in human endothelial nitric-oxide synthase.
    The Journal of biological chemistry, 2003, Dec-26, Volume: 278, Issue:52

    Topics: Amino Acid Sequence; Animals; Baculoviridae; Calcium; Calmodulin; Catalysis; Chelating Agents; Citrulline; Culture Media; Cytochromes c; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Ferricyanides; Gene Deletion; Humans; Insecta; Molecular Sequence Data; Mutation; NADP; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oxygen; Protein Structure, Tertiary; Sequence Homology, Amino Acid

2003
Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Dec-09, Volume: 100, Issue:25

    Topics: Animals; Arginine; Catalysis; Chromatography, High Pressure Liquid; Citrulline; Electrochemistry; Escherichia coli; Feedback, Physiological; Hydrogen Peroxide; Inflammation; Kinetics; Mice; Milk; Models, Biological; Models, Chemical; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxygen; Peroxidase; Protein Binding; RNA, Messenger; Spectrophotometry; Time Factors; Ultraviolet Rays; Up-Regulation

2003
Activation of the nitric oxide response in gilthead seabream after experimental infection with Photobacterium damselae subsp. piscicida.
    Fish & shellfish immunology, 2004, Volume: 16, Issue:5

    Topics: Analysis of Variance; Animals; Bacterial Capsules; Body Constitution; Citrulline; Fish Diseases; Glucose; Gram-Negative Bacterial Infections; Lethal Dose 50; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Photobacterium; Sea Bream; Time Factors; Virulence

2004
Increased (E)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression.
    Journal of affective disorders, 2004, Volume: 80, Issue:2-3

    Topics: Aldehydes; Arginine; Citrulline; Coronary Disease; Depressive Disorder, Major; Female; Glutathione; Humans; Lipid Peroxidation; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites

2004
The role of carbon monoxide and nitric oxide in hyperosmolality-induced atrial natriuretic peptide release by hypothalamus in vitro.
    Brain research, 2004, Jul-30, Volume: 1016, Issue:1

    Topics: Analysis of Variance; Animals; Atrial Natriuretic Factor; Carbon Monoxide; Citrulline; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hemoglobins; Hypothalamus; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; omega-N-Methylarginine; Osmolar Concentration; Potassium Chloride; Rats

2004
Role of nitric oxide pathway in hypotensive and renal effects of furosemide during extracellular volume expansion.
    Journal of hypertension, 2004, Volume: 22, Issue:8

    Topics: Animals; Blood Pressure; Blood Volume; Carbon Radioisotopes; Citrulline; Diuresis; Diuretics; Extracellular Fluid; Furosemide; Hypotension; Kidney; Male; NADPH Dehydrogenase; Natriuresis; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Renal Circulation

2004
Nitric oxide formation in the oropharyngeal tract: possible influence of cigarette smoking.
    Nitric oxide : biology and chemistry, 2004, Volume: 11, Issue:3

    Topics: Adult; Aged; Biopsy; Citrulline; Humans; Immunohistochemistry; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Oropharynx; Saliva; Smoking

2004
Direct single cell determination of nitric oxide synthase related metabolites in identified nitrergic neurons.
    Journal of inorganic biochemistry, 2005, Volume: 99, Issue:4

    Topics: Animals; Arginine; Argininosuccinic Acid; Cells, Cultured; Citrulline; Electric Conductivity; Electrophoresis, Capillary; Ganglia, Invertebrate; Intracellular Fluid; Lymnaea; Microscopy, Fluorescence; Nitrates; Nitrergic Neurons; Nitric Oxide Synthase; Nitrites; Ornithine

2005
Increased NO production in lysinuric protein intolerance.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:2

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acid Transport System y+L; Cells, Cultured; Child; Citrulline; Fibroblasts; Fusion Regulatory Protein 1, Light Chains; Humans; Lysine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites

2005
Effects of acute ammonia toxicity on nitric oxide (NO), citrulline-NO cycle enzymes, arginase and related metabolites in different regions of rat brain.
    Neuroscience research, 2005, Volume: 53, Issue:2

    Topics: Amino Acids; Ammonia; Animals; Arginase; Argininosuccinate Lyase; Argininosuccinate Synthase; Brain; Citrulline; gamma-Aminobutyric Acid; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley

2005
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Sep-20, Volume: 102, Issue:38

    Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Arteriosclerosis; Ascorbic Acid; Citrulline; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Diet, Atherogenic; DNA-Binding Proteins; Endothelium, Vascular; ets-Domain Protein Elk-1; Humans; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Proto-Oncogene Proteins; Rabbits; Superoxides; Transcription Factors; Vasodilation; Vitamin E

2005
Vascular and renal effects of dopamine during extracellular volume expansion: Role of nitric oxide pathway.
    Life sciences, 2006, Feb-28, Volume: 78, Issue:14

    Topics: Animals; Aorta; Arginine; Blood Pressure; Citrulline; Diuresis; Dopamine; Dopamine Antagonists; Extracellular Fluid; Haloperidol; Kidney; Male; NADPH Dehydrogenase; Natriuresis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Renal Artery; Renal Plasma Flow

2006
Infected chronic wounds show different local and systemic arginine conversion compared with acute wounds.
    The Journal of surgical research, 2006, Volume: 134, Issue:2

    Topics: Acute Disease; Adult; Amino Acids; Arginase; Arginine; Body Fluids; Chronic Disease; Citrulline; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Ornithine; Prospective Studies; Wound Healing; Wound Infection; Wounds and Injuries

2006
Arginine, citrulline and nitrate concentrations in the cerebrospinal fluid from patients with acute hydrocephalus.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, May-15, Volume: 851, Issue:1-2

    Topics: Adult; Albumins; Amino Acids; Arginine; Case-Control Studies; Citrulline; Humans; Hydrocephalus; Middle Aged; Nitrates

2007
Measurement of NO and NO synthase.
    Current protocols in neuroscience, 2001, Volume: Chapter 7

    Topics: Animals; Arginine; Citrulline; Colorimetry; Ethylenediamines; Luminescent Measurements; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Sulfanilamides

2001
Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia.
    Neurochemistry international, 2008, Volume: 53, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Citrulline; Dementia, Multi-Infarct; Female; Functional Laterality; Glutamine; Hippocampus; Humans; Isoenzymes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Schizophrenia; Signal Transduction

2008
Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy.
    Amino acids, 2009, Volume: 37, Issue:4

    Topics: Adult; Aged; Arginine; Blood Platelets; Carcinoma, Renal Cell; Citrulline; Female; Humans; Interferon-alpha; Kidney Neoplasms; Male; Melanoma; Middle Aged; Monoamine Oxidase; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Skin Neoplasms

2009
L-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 297, Issue:3

    Topics: Amino Acids; Animals; Animals, Newborn; Blotting, Western; Chronic Disease; Citrulline; Exhalation; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Perfusion; Pressure; Pulmonary Artery; Sus scrofa

2009
Nitric oxide (NO), citrulline-NO cycle enzymes, glutamine synthetase, and oxidative status in kainic acid-mediated excitotoxicity in rat brain.
    Drug and chemical toxicology, 2009, Volume: 32, Issue:4

    Topics: Animals; Aspartic Acid; Brain; Citrulline; Endothelium, Vascular; Glutamate-Ammonia Ligase; Kainic Acid; Muscle Relaxation; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; RNA, Messenger

2009
Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase.
    Neurochemistry international, 2010, Volume: 56, Issue:4

    Topics: Animals; Arginine; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Citrulline; Cyclic AMP; Cyclic GMP; Enzyme Activation; Excitatory Amino Acid Agonists; Guanylate Cyclase; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Oncogene Protein v-akt; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate

2010
Potential utility of full-spectrum antioxidant therapy, citrulline, and dietary nitrate in the management of sickle cell disease.
    Medical hypotheses, 2010, Volume: 74, Issue:6

    Topics: Anemia, Sickle Cell; Animals; Antioxidants; Arginine; Citrulline; Hemoglobins; Humans; Models, Biological; Nitrates; Nitric Oxide; Oxidative Stress; Vegetables

2010
Involvement of autoimmunity in the pathogenesis of aggressive periodontitis.
    Journal of dental research, 2010, Volume: 89, Issue:12

    Topics: Adult; Aggressive Periodontitis; Autoantibodies; Autoantigens; Autoimmunity; Chronic Periodontitis; Citrulline; Collagen Type I; Collagen Type III; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Female; Filaggrin Proteins; Fluorescence; Gingivitis; Humans; Hydroxyl Radical; Hypochlorous Acid; Imaging, Three-Dimensional; Intermediate Filament Proteins; Male; Middle Aged; Nitrates; Oxidants; Phosphoproteins; Protein Precursors; Protein Processing, Post-Translational; Reactive Oxygen Species; Young Adult

2010
Continuous exposure to L-arginine induces oxidative stress and physiological tolerance in cultured human endothelial cells.
    Amino acids, 2012, Volume: 43, Issue:3

    Topics: Arginase; Arginine; Ascorbic Acid; Cells, Cultured; Citrulline; Culture Media; Down-Regulation; Drug Tolerance; Free Radical Scavengers; Gene Expression; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Polyethylene Glycols; Superoxide Dismutase; Superoxides

2012
Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs.
    Biochemical and biophysical research communications, 2012, Oct-12, Volume: 427, Issue:1

    Topics: Adenosine Diphosphate; Animals; Arginine; Arginine Kinase; Catalytic Domain; Citrulline; Crystallography, X-Ray; Horseshoe Crabs; Nitrates; Protein Structure, Tertiary

2012
Disturbance of redox homeostasis by ornithine and homocitrulline in rat cerebellum: a possible mechanism of cerebellar dysfunction in HHH syndrome.
    Life sciences, 2013, Aug-06, Volume: 93, Issue:4

    Topics: Aconitate Hydratase; Animals; Cerebellum; Citrulline; Creatine Kinase; Electron Transport; Glutathione; Homeostasis; Hydrogen Peroxide; Hyperammonemia; Ketoglutarate Dehydrogenase Complex; Nerve Tissue Proteins; Nitrates; Nitrites; Ornithine; Oxidation-Reduction; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances; Urea Cycle Disorders, Inborn

2013
Two different approaches to restore renal nitric oxide and prevent hypertension in young spontaneously hypertensive rats: l-citrulline and nitrate.
    Translational research : the journal of laboratory and clinical medicine, 2014, Volume: 163, Issue:1

    Topics: Animals; Arginine; Citrulline; Dietary Supplements; Hypertension; Male; Nitrates; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2014
Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis.
    Antioxidants & redox signaling, 2015, Aug-01, Volume: 23, Issue:4

    Topics: Animals; Aorta; Arginine; Blood Pressure; Cardiovascular System; Citrulline; Dietary Supplements; Homeostasis; Male; Metabolic Networks and Pathways; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Phosphorylation; Rats, Sprague-Dawley

2015
Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation.
    American journal of physiology. Renal physiology, 2014, Dec-01, Volume: 307, Issue:11

    Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Fibronectins; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred DBA; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Tumor Necrosis Factor-alpha

2014
Effects of hyperbaric oxygen on nitric oxide generation in humans.
    Nitric oxide : biology and chemistry, 2015, Jan-30, Volume: 44

    Topics: Adult; Arginine; Breath Tests; Citrulline; Cyclic GMP; Humans; Hyperbaric Oxygenation; Nitrates; Nitric Oxide; Nitrites; Oxygen; Saliva; Tongue; Young Adult

2015
Plasma kallikrein-bradykinin pathway promotes circulatory nitric oxide metabolite availability during hypoxia.
    Nitric oxide : biology and chemistry, 2016, 05-01, Volume: 55-56

    Topics: Acclimatization; Adult; Altitude; Angiotensinogen; Arginine; Bradykinin; Citrulline; Humans; Hypoxia; Isoprostanes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Oxidative Stress; Plasma Kallikrein; Protein Carbonylation; Proteome; Signal Transduction

2016
Participation of oleic acid in the formation of the aortic aneurysm in Marfan syndrome patients.
    Prostaglandins & other lipid mediators, 2016, Volume: 123

    Topics: Adult; Aorta; Aortic Aneurysm; Arachidonic Acid; Case-Control Studies; Cholesterol, HDL; Citrulline; Collagen; Female; Gene Expression Regulation; Humans; Male; Marfan Syndrome; Middle Aged; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Oleic Acid; Prospective Studies; Signal Transduction; Stearoyl-CoA Desaturase; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2016
Oral nitrate and citrulline decrease blood pressure and increase vascular conductance in young adults: a potential therapy for heart failure.
    European journal of applied physiology, 2016, Volume: 116, Issue:9

    Topics: Administration, Oral; Blood Flow Velocity; Blood Pressure; Cardiotonic Agents; Citrulline; Dietary Supplements; Dose-Response Relationship, Drug; Feasibility Studies; Female; Heart Failure; Heart Rate; Humans; Male; Nitrates; Treatment Outcome; Vascular Resistance; Vasodilation

2016
The Effect Of NO Donor on Calcium Uptake and Reactive Nitrogen Species Production in Mitochondria.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:1

    Topics: Animals; Biological Transport; Calcium; Citrulline; Dose-Response Relationship, Drug; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroglycerin; Rats, Wistar; Reactive Nitrogen Species; S-Nitrosothiols

2016
A pilot study of a non-invasive oral nitrate stable isotopic method suggests that arginine and citrulline supplementation increases whole-body NO production in Tanzanian children with sickle cell disease.
    Nitric oxide : biology and chemistry, 2018, 04-01, Volume: 74

    Topics: Administration, Oral; Anemia, Sickle Cell; Arginine; Child; Citrulline; Dietary Supplements; Female; Humans; Male; Nitrates; Nitric Oxide; Nitrogen Isotopes; Pilot Projects; Tanzania

2018
Pharmacological activation of dimethylarginine dimethylaminohydrolase (DDAH) activity by inorganic nitrate and DDAH inhibition by N
    Amino acids, 2019, Volume: 51, Issue:3

    Topics: Amidohydrolases; Animals; Arginine; Citrulline; Liver; Nitrates; Rats; Recombinant Proteins

2019
Nitric oxide synthase-mediated early nitric oxide burst alleviates water stress-induced oxidative damage in ammonium-supplied rice roots.
    BMC plant biology, 2019, Mar-20, Volume: 19, Issue:1

    Topics: Ammonium Compounds; Antioxidants; Arginine; Citrulline; Dehydration; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oryza; Oxidation-Reduction; Plant Proteins; Plant Roots

2019