nitracrine has been researched along with acridines in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (75.00) | 18.7374 |
| 1990's | 3 (9.38) | 18.2507 |
| 2000's | 2 (6.25) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Dobryszycka, W; Narczeuska, B; Warwas, M | 1 |
| Konopa, J; Pawlak, JW | 1 |
| Krawczyk, K; Krochmal, M; Pawlicki, M | 1 |
| Szulc, K | 2 |
| Chalupka, G; Chorazy, M; Filipski, J; Marczyński, B; Sadzińska, L | 1 |
| Morzycka, M; Pankowska, B; Szulc, K | 1 |
| Kadlubowski, R; Kurnatowska, A | 1 |
| Morzycka, M; Szulc, K | 1 |
| Gniazdowski, M; Jaros-Kamińska, B; Malagocka, S; Szmigiero, L; Wilmańska, D | 1 |
| Giełdanowski, J; Skowrońska, J | 1 |
| Ciesielska, E; Gniazdowski, M; Jaros-Kamińska, B; Slaska, K; Szmigiero, L | 3 |
| Krawczyk, K; Pawlicki, M | 1 |
| Dereń, K; Oleszkiewicz, L; Szroeder, J; Zarzycki, J | 1 |
| Błaszczyk, B; Giełdanowski, J; Kowalczyk-Bronisz, SH; Patkowski, J | 1 |
| Hrabowska, M; Ledóchowski, A; Onoszko, K | 1 |
| Krzyzowska-Gruca, S; Kulczycka, E; Marczyński, B | 1 |
| Chalupka, G; Chorazy, M; Jerzykowski, T; Szalsza-Kuśnierczyk, M | 1 |
| Koldej, K; Konopa, J; Pawlak, JW | 1 |
| Chorazy, M; Kalinowska, E | 1 |
| Gniazdowski, M; Szmigiero, L | 1 |
| Kowalczyk-Bronisz, SH | 1 |
| Ciesielska, E; Pastwa, E; Studzian, K; Szmigiero, L | 1 |
| Denny, WA; Ferry, DM; Lee, HH; Pullen, SM; van Zijl, P; Wilson, WR | 1 |
| Denny, WA; Lee, HH; Li, AE; Patterson, LH; Pullen, SM; Thompson, KM; Wilson, WR | 1 |
| Baguley, BC; Hicks, KO; Pruijn, FB; Wilson, WR | 1 |
| Denny, WA; Ferguson, LR; Hoffmann, GR; Terry, CE; Yin, CC | 1 |
| Dastych, J; Mazerska, Z; Niemira, M | 1 |
| Augustin, E; Hołownia, A; Mazerska, Z; Niemira, M | 1 |
| Andrałojć, W; Borzyszkowska-Bukowska, J; Frackowiak, JE; Kosno, M; Laskowski, T; Mazerska, Z; Paluszkiewicz, E; Radoń, N; Świerżewska, M; Szczeblewski, P; Woźny, A | 1 |
1 trial(s) available for nitracrine and acridines
| Article | Year |
|---|---|
[Interferon induction with C 283 acridine derivative].
Topics: Acridines; Animals; Clinical Trials as Topic; Evaluation Studies as Topic; Interferon Inducers; Male; Mice; Nitracrine | 1977 |
31 other study(ies) available for nitracrine and acridines
| Article | Year |
|---|---|
Blood serum peptidases in patients with ovarian carcinoma treated with Ledakrin.
Topics: Acridines; Amidohydrolases; Ascites; Cobalt; Female; gamma-Glutamyltransferase; Humans; Kidney; Leucyl Aminopeptidase; Liver; Nitracrine; Ovarian Neoplasms | 1977 |
In vitro binding of metabolically activated [14C]-ledakrin, or 1-nitro-9-14C-(3'-dimethylamino-N-propylamino) acridine, a new antitumor and DNA cross-linking agent, to macromolecules of subcellular fractions isolated from rat liver and HeLa cells.
Topics: Acridines; Animals; Cytosol; HeLa Cells; Humans; Hydroxylamines; In Vitro Techniques; Liver; Macromolecular Substances; Male; NADP; Nitracrine; Rats; Subcellular Fractions | 1979 |
[Early results of ledakrin treatment in cases of advanced lung carcinoma].
Topics: Acridines; Humans; Lung Neoplasms; Male; Nitracrine; Palliative Care | 1978 |
[Antiviral effect of acridine derivative C 283].
Topics: Acridines; Antiviral Agents; Encephalitis Virus, Western Equine; Herpes Simplex; Nitracrine; Poliovirus; Vaccinia virus; Virus Replication | 1976 |
[Antiviral effects of acridine derivative C 283 in Herpes simplex studies].
Topics: Acridines; Antiviral Agents; Nitracrine; Simplexvirus; Time Factors; Virus Replication | 1976 |
Interactions of some nitro-derivatives of substituted 9-aminoacridine with DNA.
Topics: Acridines; Animals; Cell Nucleus; DNA; DNA, Neoplasm; DNA, Viral; Leukemia L1210; Liver; Mice; Nitracrine; RNA; RNA, Neoplasm; Simian virus 40; Structure-Activity Relationship; Transcription, Genetic | 1977 |
[In vivo effect of C-283 acridine derivative on Herpes simplex virus].
Topics: Acridines; Animals; Keratitis, Dendritic; Nitracrine; Rabbits; Simplexvirus | 1977 |
[Bacteriostatic, antimycotic and antitrichomonal effects in vitro of a new antineoplastic drug, Ledakrin, Polfa].
Topics: Acridines; Bacteria; Fungi; Nitracrine; Trichomonas; Trichomonas vaginalis | 1977 |
[Effect of 1-nitro-9-aminoalkylacridine (Ledakrin, C-283) binding with chromatin on DNA template activity (preliminary report)].
Topics: Acridines; Chromatin; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Nitracrine; Templates, Genetic | 1977 |
Immunosuppressive activity of ledakrin.
Topics: Acridines; Animals; Antibody-Producing Cells; Dose-Response Relationship, Drug; Hemolytic Plaque Technique; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Mice; Mice, Inbred Strains; Nitracrine; Rosette Formation | 1979 |
The mechanism of inhibition of DNA transcription in vitro by nitracrine (Ledakrin, C-283).
Topics: Acridines; Base Composition; Chemical Phenomena; Chemistry; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Nitracrine; Templates, Genetic; Transcription, Genetic | 1979 |
[Results of therapeutic use of ledakrin in cancer-induced pleural effusion].
Topics: Acridines; Adult; Aged; Breast Neoplasms; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Nitracrine; Pleural Effusion; Remission, Spontaneous | 1979 |
The effect of Ledacrin on elements of the lobulus in human liver.
Topics: Acridines; Cytoplasm; Humans; Liver; Liver Neoplasms; Microscopy, Electron; Nitracrine | 1979 |
Pharmacological studies on new oncostatic acridine derivatives. I. Acute and subchronic action.
Topics: Acridines; Aminoacridines; Animals; Antineoplastic Agents; Drug Interactions; Female; Guinea Pigs; Hemodynamics; Hypnotics and Sedatives; In Vitro Techniques; Lethal Dose 50; Male; Mice; Muscle, Smooth; Nitracrine; Rats; Reproduction; Respiration | 1979 |
Structure of acridines and their effect on RNA synthesis in vitro.
Topics: Acridines; Chemical Phenomena; Chemistry; Depression, Chemical; DNA-Directed RNA Polymerases; Nitracrine; RNA; RNA, Bacterial; Sulfhydryl Compounds | 1977 |
A search for antitumor compounds. XII. Biologic studies. Antitumor properties of 12 new 1-nitro-9alkylaminoalkylaminoacridines.
Topics: Acridines; Animals; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Neoplasm Transplantation; Nitracrine; Sarcoma 180; Structure-Activity Relationship | 1977 |
Effects of some 9-aminoacridine derivatives on the nucleus and nucleolus.
Topics: Acridines; Animals; Cell Nucleolus; Cell Nucleus; Female; Nitracrine; Rats | 1976 |
Excretion and organ distribution of the cytostatic preparation Ledakrin (preparation C-283) in rat.
Topics: Acridines; Animals; Antineoplastic Agents; Feces; Nitracrine; Rats | 1976 |
Influence of thiols on inhibition of ribonucleic acid synthesis in vitro by a 1-nitro-9-aminoalkylacridine derivative, C-283.
Topics: Acridines; Depression, Chemical; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Ethidium; Nitracrine; RNA, Bacterial; Sulfhydryl Compounds; Templates, Genetic; Transcription, Genetic | 1975 |
Covalent binding of 1-nitro-9-(3-dimethyl-n-propylamino) acridine, a new antitumor drug, to DNA of Ehrlich ascites tumor cells in vivo.
Topics: Acridines; Animals; Antineoplastic Agents; Binding Sites; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Kinetics; Mice; Nitracrine; Nucleic Acid Denaturation; Temperature | 1976 |
Mutagenic activity of some 9-aminoalkyl acridine derivatives on S. typhimurium.
Topics: Acridines; Aminoacridines; Drug Evaluation, Preclinical; Genetic Techniques; Mutagens; Nitracrine; Salmonella typhimurium | 1980 |
Complexes of nitracrine with DNA. Stoichiometry of binding.
Topics: Acridines; Aminoacridines; Chemical Phenomena; Chemistry; Dithiothreitol; DNA; Mercaptoethanol; Nitracrine | 1981 |
Studies on vomitory effect of some acridine compounds.
Topics: Acridines; Animals; Columbidae; Drug Evaluation, Preclinical; Drug Synergism; Emetics; Female; Lobeline; Male; Nitracrine; Vomiting | 1980 |
DNA-protein crosslinks induced in HeLa cells by bis-1-nitroacridines.
Topics: Acridines; Antineoplastic Agents; Cell Division; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Nitracrine; Nitro Compounds | 1993 |
Hypoxia-selective antitumor agents. 13. Effects of acridine substitution on the hypoxia-selective cytotoxicity and metabolic reduction of the bis-bioreductive agent nitracrine N-oxide.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Division; Cell Hypoxia; Cell Line; Cell Survival; Cricetinae; Cricetulus; Culture Media; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C3H; Molecular Structure; Nitracrine; Oxidation-Reduction; Tumor Cells, Cultured | 1996 |
Tertiary amine N-oxides as bioreductive drugs: DACA N-oxide, nitracrine N-oxide and AQ4N.
Topics: Acridines; Animals; Anthraquinones; Antineoplastic Agents; Cell Survival; Humans; Intercalating Agents; Mammary Neoplasms, Experimental; Mice; Nitracrine; Oxidation-Reduction; Prodrugs; Xanthenes; Xanthones | 1996 |
Extravascular transport of the DNA intercalator and topoisomerase poison N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide (DACA): diffusion and metabolism in multicellular layers of tumor cells.
Topics: Acridines; Animals; Antineoplastic Agents; Area Under Curve; Biological Transport; Body Fluid Compartments; Carbon Radioisotopes; Cell Line; Chromatography, High Pressure Liquid; Computer Simulation; Cricetinae; Diffusion; Diffusion Chambers, Culture; Drug Design; Fibroblasts; Intercalating Agents; Mammary Neoplasms, Experimental; Mice; Models, Biological; Nitracrine; Topoisomerase II Inhibitors; Urea | 2001 |
Frameshift mutations induced by four isomeric nitroacridines and their des-nitro counterpart in the lacZ reversion assay in Escherichia coli.
Topics: Acridines; Antineoplastic Agents; Dose-Response Relationship, Drug; Escherichia coli; Frameshift Mutation; Lac Operon; Molecular Structure; Mutagenicity Tests; Nitracrine | 2006 |
Pregnane X receptor dependent up-regulation of CYP2C9 and CYP3A4 in tumor cells by antitumor acridine agents, C-1748 and C-1305, selectively diminished under hypoxia.
Topics: Acridines; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Western; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; DNA Primers; Hep G2 Cells; Humans; Hypoxia; Nitracrine; Pregnane X Receptor; Real-Time Polymerase Chain Reaction; Receptors, Steroid; Triazoles; Up-Regulation | 2013 |
CYP3A4-dependent cellular response does not relate to CYP3A4-catalysed metabolites of C-1748 and C-1305 acridine antitumor agents in HepG2 cells.
Topics: Acridines; Antineoplastic Agents; Biocatalysis; Cell Cycle Checkpoints; Cell Survival; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Hep G2 Cells; Humans; Mass Spectrometry; Nitracrine; Triazoles | 2014 |
The interactions of monomeric acridines and unsymmetrical bisacridines (UAs) with DNA duplexes: an insight provided by NMR and MD studies.
Topics: Acridines; Chemometrics; DNA; Intercalating Agents; Magnetic Resonance Imaging; Nitracrine | 2023 |