nitd008 and triphosphoric-acid

nitd008 has been researched along with triphosphoric-acid* in 1 studies

Other Studies

1 other study(ies) available for nitd008 and triphosphoric-acid

Article	Year
The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors. Scientific reports, 2018, 07-24, Volume: 8, Issue:1 Zika virus is a global health threat due to significantly elevated risk of fetus malformations in infected pregnant women. Currently, neither an effective therapy nor a prophylactic vaccination is available for clinical use, desperately necessitating novel therapeutics and approaches to obtain them. Here, we present a structural model of the Zika virus RNA-dependent RNA polymerase (ZIKV RdRp) in complex with template and nascent RNAs, Mg Topics: Adenosine; Humans; Magnesium; Models, Molecular; Molecular Docking Simulation; Nucleosides; Nucleotides; Polyphosphates; Protein Conformation; RNA; RNA-Dependent RNA Polymerase; Viral Nonstructural Proteins; Virus Replication; Zika Virus; Zika Virus Infection	2018

Article

Year

The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors.

Scientific reports, 2018, 07-24, Volume: 8, Issue:1

Zika virus is a global health threat due to significantly elevated risk of fetus malformations in infected pregnant women. Currently, neither an effective therapy nor a prophylactic vaccination is available for clinical use, desperately necessitating novel therapeutics and approaches to obtain them. Here, we present a structural model of the Zika virus RNA-dependent RNA polymerase (ZIKV RdRp) in complex with template and nascent RNAs, Mg

Topics: Adenosine; Humans; Magnesium; Models, Molecular; Molecular Docking Simulation; Nucleosides; Nucleotides; Polyphosphates; Protein Conformation; RNA; RNA-Dependent RNA Polymerase; Viral Nonstructural Proteins; Virus Replication; Zika Virus; Zika Virus Infection

2018