nitazoxanide has been researched along with thiazoles in 458 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (0.44) | 18.7374 |
| 1990's | 26 (5.68) | 18.2507 |
| 2000's | 137 (29.91) | 29.6817 |
| 2010's | 197 (43.01) | 24.3611 |
| 2020's | 96 (20.96) | 2.80 |
| Authors | Studies |
|---|---|
| Friedmann, JC; Murphy, JR | 1 |
| Maisonneuve, H; Rossignol, JF | 1 |
| Calderon, P; Deroubaix, X; Jeanbaptiste, B; Lins, R; Rossignol, JF; Stockis, A | 1 |
| Dubreuil, L; Houcke, I; Mouton, Y; Rossignol, JF | 1 |
| Dembele, TM; Diakite, M; Diallo, DA; Doumbo, O; Pichard, E; Rossignol, JF; Traore, F; Traore, HA | 1 |
| D'Onfro, J; Fairfield, A; Griffiths, JK; Theodos, CM; Tzipori, S | 1 |
| Mégraud, F; Occhialini, A; Rossignol, JF | 1 |
| Blagburn, BL; Boykin, DW; Drain, KL; Kinard, RG; Land, TM; Lindsay, DS; Moore, PH; Patrick, DA; Tidwell, RR | 1 |
| Geary, TG; Sangster, NC; Thompson, DP | 1 |
| Bicart-Sée, A; Datry, A; Linas, MD; Massip, P | 1 |
| Barchiesi, F; Burzacchini, F; Cirioni, O; Dini, M; Giacometti, A; Scalise, G | 1 |
| Ancarani, F; Barchiesi, F; Cirioni, O; Giacometti, A; Scalise, G | 1 |
| Ballet, JJ; Brasseur, P; Delaunay, A; Favennec, L; Gargala, G; Li, X | 1 |
| Vdovenko, AA; Williams, JE | 1 |
| McVay, CS; Rolfe, RD | 1 |
| Broekhuysen, J; De Graeve, J; Lins, RL; Rossignol, JF; Stockis, A | 1 |
| Abdel-Maboud, AI; el-Kady, MS; Kabil, SM; Mostafa, MS; Rossignol, JF | 1 |
| Abboud, P; Ballet, JJ; Borsa-Lebas, F; Brasseur, P; Caron, F; Favennec, L; Gargala, G; Lemée, V | 1 |
| Smart, T | 2 |
| Young, A | 2 |
| Cooper, S | 1 |
| James, JS | 2 |
| Bornhoeft, MA | 1 |
| Bowers, M | 1 |
| Ayers, MS; Ayoub, A; Rossignol, JF | 2 |
| Bialek, R; Knobloch, J; Overkamp, D; Rettig, I | 1 |
| Ayoub, A; Chegne, NL; Favennec, L; Gargala, G; Ortiz, JJ | 1 |
| Breitschwerdt, EB; Gookin, JL; Law, JM; Levy, MG; Papich, MG; Poore, MF | 1 |
| Adagu, IS; Nolder, D; Rossignol, JF; Warhurst, DC | 1 |
| Gilles, HM; Hoffman, PS | 1 |
| Arya, SC | 1 |
| Allemon, AM; De Bruyn, S; Gengler, C; Stockis, A | 1 |
| De Bruyn, S; Gengler, C; Rosillon, D; Stockis, A | 1 |
| Berg, DE; Goodwin, A; Hoffman, PS; Hughes, NJ; Mukhopadhyay, AK; Raudonikiene, A; Sisson, G | 1 |
| Davila-Gutierrez, CE; Huerta, M; Trujillo-Hernandez, B; Vasquez, C | 1 |
| Heyman, M; Matysiak-Budnik, T; Mégraud, F | 1 |
| Amadi, B; Ayoub, A; Kelly, P; Musuku, J; Mwiya, M; Sianongo, S; Watuka, A | 1 |
| Ayoub, A; Favennec, L; Gargala, G; Jave Ortiz, J; Lopez Chegne, N; Rossignol, JF | 1 |
| Fink, R; Geary, TG; Gottstein, B; Hemphill, A; Rossignol, JF; Stettler, M; Walker, M | 1 |
| Agnamey, P; Ballet, JJ; Brasseur, P; Favennec, L; Leméteil, D; Li, X; Rossignol, JF | 1 |
| Lobovská, A; Nohýnková, E | 1 |
| White, AC | 1 |
| Bernal, R; Diaz, E; Mondragon, J; Ramirez, E | 1 |
| Okhuysen, PC; Robinson, P; White, AC | 1 |
| Fonseca-Salamanca, F; Martínez-Fernández, AR; Martínez-Grueiro, MM | 1 |
| Dusci, L; Guttner, Y; Marshall, BJ; Viiala, CH; Windsor, HM | 1 |
| Hussar, DA | 1 |
| Moustafa, MA | 1 |
| Bailey, JM; Erramouspe, J | 1 |
| Dricot, E; Fink, R; Gottstein, B; Hemphill, A; Merli, M; Rossignol, JF; Segers, R; Stettler, M; Theurillat, R; Thormann, W; Walker, M | 1 |
| Hemphill, A; Rossignol, JF; Torgerson, P; Walker, M | 1 |
| Armson, A; Reynoldson, JA; Thompson, RC | 1 |
| White, CA | 1 |
| Chappell, C; Huang, DB; Okhuysen, PC | 1 |
| Jenkins, MC | 1 |
| Farthing, M; Kaonga, K; Kelly, P; McDonald, V; Njobvu, L; Pollok, R; Sianongo, S; Zulu, I | 1 |
| Fox, LM; Saravolatz, LD | 1 |
| Ochoa, TJ; White, AC | 1 |
| Cohen, SA | 1 |
| Berry, NG; Esposito, M; Hemphill, A; Moores, SL; Müller, N; Pidathala, C; Rossignol, JF; Stachulski, A; Stettler, R | 1 |
| Kabil, SM; Rossignol, JF; Said, M; Samir, H; Younis, AM | 1 |
| Arya, R; Parashar, A | 1 |
| Gottstein, B; Haag, K; Hemphill, A; Matsumoto, J; Mejri, N; Walker, M | 1 |
| Baishanbo, A; Ballet, JJ; Duclos, C; Favennec, L; François, A; Gargala, G; Rossignol, JF | 1 |
| Hemphill, A; Müller, J; Müller, N; Rossignol, JF; Rühle, G | 1 |
| Gottstein, B; Hemphill, A; Kamiya, M; Matsumoto, J; Müller, N; Oku, Y | 1 |
| Appelbaum, PC; Pankuch, GA | 1 |
| el-Gohary, Y; Kabil, SM; Rossignol, JF; Younis, AM | 2 |
| Esposito, M; Hemphill, A; Mueller, J | 1 |
| Blanco, EM; Bustos, JA; Chero, JC; Garcia, HH; Gonzalvez, G; Saito, M | 1 |
| Franco, M; Lanata, CF | 1 |
| Abu-Zekry, M; Hussein, A; Rossignol, JF; Santoro, MG | 1 |
| Dupont, HL; Gupta, A; Hamill, RJ; Lentnek, A; Logan, N; Musher, DM; Rossignol, JF | 1 |
| Rossignol, JF | 4 |
| Alam, S; Bhatnagar, S | 1 |
| Härter, G; Kern, P; Manfras, B; Merkle, M; Reuter, S | 1 |
| Debonne, JM; Rey, P | 1 |
| Aupée, O; Bohand, X | 1 |
| El-Gohary, YM; Rossignol, JF | 1 |
| Jung-Cook, H; Ortiz-Plata, A; Palencia, G; Palomares-Alonso, F; Piliado, JC | 1 |
| Bouza, E; Burillo, A; Muñoz, P | 1 |
| Esposito, M; Hemphill, A; Müller, N | 1 |
| Koletar, SL; Mangino, JE; Stevenson, KB; Young, JD | 1 |
| Cremades, N; Croxen, MA; Harman, WD; Hoffman, PS; Morash, MG; Sisson, G; Welch, K | 1 |
| Franco-Paredes, C; Schuetz, AN; Zimmer, SM | 1 |
| Bandettini, R; Cappelli, B; Castagnola, E; Coccia, C; Di Martino, D; Faraci, M; Lanino, E; Moroni, C; Morreale, G; Terranova, MP | 1 |
| Cortes, HC; Esposito, M; Hemphill, A; Leitão, A; Mueller, N; Naguleswaran, A | 1 |
| Abubakar, I; Aliyu, SH; Arumugam, C; Hunter, PR; Usman, NK | 1 |
| Garud, S; Hamill, RJ; Logan, N; Mehendiratta, V; Melgarejo, NA; Musher, DM | 1 |
| Ali, MA; Borum, ML; Entwisle, C; Long, SE; Orenstein, JM; Ramsay, DB; Rossi, C | 1 |
| Hemphill, A; Müller, J; Müller, N; Sanderson, S; Wastling, J | 1 |
| Dan, M; Sobel, JD | 1 |
| Hemphill, A; Müller, J; Müller, N; Sterk, M | 1 |
| Acero, J; Avila, X; Bernal, R; Galvan-Ramirez, ML; Loeza, ME; Rivera, N; Troyo, R | 1 |
| Balagopal, A; Sears, CL | 1 |
| Hemphill, A; Müller, J; Müller, N; Naguleswaran, A | 1 |
| Anderson, VR; Curran, MP | 1 |
| Chartier, C; Martin, J; Rocques, H; Viel, H | 1 |
| Ayers, MS; Farrar, K; Gaye, K; Korba, BE; Montero, AB; Mukerjee, S; Rossignol, JF | 1 |
| Bronze, MS; Greenfield, R; Greenfield, RA; Salvaggio, M; Sud, B | 1 |
| Katakura, K; Kido, Y; Kita, K; Matsumoto, J; Miyoshi, H; Nonaka, N; Oku, Y; Sakamoto, K; Shinjyo, N; Yagi, K; Yamamoto, N | 1 |
| Khan, AR; Lateef, M; Nazir, M; Shoukat, A; Zargar, SA | 1 |
| Aslam, S; Musher, DM | 1 |
| Nozaki, T | 1 |
| Agarwal, S; Chattaraj, TK; Ghosh, D; Gowda, KV; Pal, TK; Sarkar, AK; Selvan, PS; Solomon, WD | 1 |
| Delgado, OM; Fernandez, G; Ramirez, O; Rodriguez-Morales, AJ; Romero, J; Silva, S | 1 |
| Campbell-Lendrum, D; Castillo-Riquelme, M; Chalabi, Z; Davies, C; Fox-Rushby, J; Guhl, F; Lord, J | 1 |
| Almirall, P; Alvarez, G; Cañete, R; Cimerman, S; Escobedo, AA; González, ME; Pérez, R; Ruiz, A | 1 |
| Al-Malki, JS; Sanad, MM | 1 |
| Felger, I; Hemphill, A; Ley, S; Müller, J; Müller, N | 1 |
| Bouchaud, O; Izri, A | 1 |
| El-Gohary, Y; Elfert, A; Kabil, SM; Keeffe, EB; Rossignol, JF | 1 |
| Gottstein, B; Hemphill, A; Keiser, J; Lany, C; Ortega-Mora, LM; Roethlisberger, C; Spicher, M; Stadelmann, B | 1 |
| Nathwani, D; Shaw, J; Smith, S | 1 |
| Elazar, M; Glenn, JS; Korba, BE; Lui, P; Rossignol, JF | 1 |
| Hiyama, Y; Sakamoto, T | 1 |
| Keeffe, EB; Rossignol, JF | 2 |
| Gargala, G | 1 |
| Capparelli, EV; Syed, SS | 1 |
| Fei, C; Qiu, M; Wang, X; Xin, R; Xue, F; Yang, F; Zhang, K; Zhang, L; Zhang, T; Zhao, Z; Zheng, W | 1 |
| Finegold, SM; Molitoris, D; Väisänen, ML | 1 |
| Fischer, K; Fischer, PU; Huang, Y; Rao, RU; Weil, GJ | 1 |
| Abraham, DR; Cotton, MF; Rabie, H | 1 |
| Deplazes, P; Hemphill, A; Kohler, L; Schnyder, M | 1 |
| Teran, CG; Teran-Escalera, CN; Villarroel, P | 1 |
| Bressler, AM; Johnson, DP; Logan, N; Musher, DM; Rossignol, JF | 1 |
| El-Gohary, Y; Elfert, A; Keeffe, EB; Rossignol, JF | 1 |
| Darling, JM; Fried, MW | 1 |
| Braslins, P; McCarthy, JS; Winning, A | 1 |
| Frosch, M; Müller, A; Stich, A; Tappe, D | 1 |
| Angelats, R; Barron, EA; Garcia, HH; Gavidia, CM; Gilman, RH; Gonzalez, AE; Jayashi, C; Lopera, L; Ninaquispe, B; Verastegui, MR; Villarreal, L | 1 |
| Bellosa, ML; Bowman, DD; Divers, TJ; Linden, TC; Nydam, DV; Ollivett, TL; Zambriski, JA | 1 |
| Chan-Bacab, MJ; Hernández-Núñez, E; Navarrete-Vázquez, G | 1 |
| Jackson, AS; Rossignol, JF; Vets, E | 1 |
| Cabada, MM; Pantenburg, B; White, AC | 1 |
| Bardin, MC; Sher, G; Yangco, BG | 1 |
| Forde, KA; Reddy, KR | 1 |
| Khattab, MA | 1 |
| Chiappa, L; Ciucci, A; La Frazia, S; Rossignol, JF; Santoro, MG | 1 |
| Elazar, M; Gehrig, EA; Glenn, JS; Liu, M; Liu, P; McKenna, SA; Puglisi, JD; Rossignol, JF | 1 |
| Calderon-Gonzalez, KG; Franco-Perez, J; Gallegos-Perez, JL; Jung-Cook, H; Ruiz-Olmedo, MI | 1 |
| Schipper, HG; Simsek, S; van Agtmael, MA; van Lienden, KP | 1 |
| Bandin, F; Baudouin, V; Carol, A; Cassaing, S; Decramer, S; Garnier, A; Guigonis, V; Kwon, T; Linas, MD; Valentin, A | 1 |
| de Carvalho, LP; Jiang, X; Lin, G; Nathan, C | 1 |
| Hehl, A; Hemphill, A; Müller, J; Müller, N; Nillius, D | 1 |
| Gonçalves, HM; Malesuik, MD; Paim, CS; Schapoval, EE; Steppe, M | 1 |
| Ayuo, PO | 1 |
| Amadi, B; Katubulushi, M; Kelly, P; Mwiya, M; Payne, L; Sianongo, S; Watuka, A | 1 |
| Ballet, JJ; Favennec, L; Gargala, G; Le Goff, L; Rossignol, JF; Stachulski, AV | 1 |
| Elfert, A; Keeffe, EB; Rossignol, JF | 1 |
| Brown, SP; Guerrant, RL; Hoffman, PS; Nataro, JP; Shamir, ER; Warthan, M | 1 |
| Takehara, T | 1 |
| Brady, PG; Brantley, SG; Keshishian, J | 1 |
| Ballard, TE; Cary, CH; Hoffman, PS; Macdonald, TL; Sifri, CD; Tchouaffi-Nana, F | 1 |
| Colvin, GA; Dalia, S | 1 |
| Fei, C; Meng, X; Wang, M; Wang, X; Xue, F; Zhang, K; Zhang, L; Zhao, Z; Zheng, W | 1 |
| Bojar, H; Knap, JP | 1 |
| Dang, MD; DuPont, HL; Garey, KW; Hasbun, R; Jiang, ZD; Koo, HL; Shah, D | 1 |
| Ballard, TE; Hoffman, PS; Koerner, T; Macdonald, TL; Olekhnovich, I; Seymour, C; Wang, X | 1 |
| Gao, H; Jin, H; Liu, Q; Ma, C; Shang, L; Wei, F; Wu, Y; Xia, Z; Zhang, R; Zhu, XQ | 1 |
| Burgess, AG; Dunn, LA; Kazimierczuk, Z; Krauer, KG; Upcroft, JA; Upcroft, P; Wright, JM | 1 |
| Batlle, C; Jiménez, C; Lopez-Velez, R; Navarro, M; Norman, F; Perez-Molina, J | 1 |
| Cabada, MM; White, AC | 1 |
| Johnson, AP | 1 |
| Dalle, F; Deconinck, E; Grenouillet, F; Larosa, F; Legrand, F; Millon, L; Rohrlich, PS; Saas, P | 1 |
| Arun Babu, T; Venkatesh, C | 1 |
| Grace, E; Gurgen, J; Hogan, D; Johnson, D | 1 |
| Ballard, TE; Hoffman, PS; Koerner, T; Macdonald, TL; Olekhnovich, I; Salamoun, J; Seymour, C; Wang, X; Warthan, M | 1 |
| Ayala, AP; Díaz-Menéndez, M; Gallego, JI; López-Vélez, R; Monge-Maillo, B; Norman, F; Pérez-Molina, JA | 1 |
| Acikgoz, Y; Bek, K; Genc, G; Hokelek, M; Ozkaya, O; Sensoy, SG | 1 |
| Kelly, P | 1 |
| Baines, SD; Freeman, J; Huscroft, GS; Todhunter, SL; Wilcox, MH | 1 |
| Müller, J; Müller, N; Nillius, D | 1 |
| Argotte-Ramos, R; Cedillo-Rivera, R; Chan-Bacab, MJ; Chávez-Silva, F; Hernández-Nuñez, E; Moo-Puc, R; Navarrete-Vazquez, G; Rodríguez-Gutiérrez, Mdel C | 1 |
| Cao, JP; Chen, SX; Fu, XL; Jiang, XG; Lu, ZX; Shen, YJ; Tu, GH; Wu, L | 1 |
| Bookstaver, PB; Miller, AD; Musgrave, CR; Sutton, SS | 1 |
| Clark, JN; Don, R; Horton, J; Keiser, J; Kuesel, A; Olliaro, P; Seiler, J | 1 |
| Korba, B; Rossignol, JF; Viswanathan, P; Yon, C | 1 |
| Costa, LB; Freire, RS; Guerrant, RL; Hoffman, PS; JohnBull, EA; Lima, AA; Oriá, RB; Reeves, JT; Roche, JK; Sevilleja, JE; Warren, CA | 1 |
| Chaudhari, HS; Singh, PP | 1 |
| Boykin, D; Debache, K; Guionaud, C; Hemphill, A; Kropf, C; Stephens, CE | 1 |
| Davids, BJ; Dunn, L; Eckmann, L; Gillin, FD; Lauwaet, T; Millman, M; Miyamoto, Y; Tejman-Yarden, N; Upcroft, JA | 1 |
| Adachi, JA; Koo, HL; Siddiq, DM; Viola, GM | 1 |
| Asaly, M; Cantor, R; Mackey, J; Nacca, NE | 1 |
| Kabil, SM; Mounier, BI; Soliman, MS; Youssef, SM | 1 |
| Basu, PP; Flynn, M; Krishnaswamy, N; Pacana, T; Rayapudi, K; Shah, NJ | 1 |
| Abusamra, L; Bolcic, F; Cahn, P; Gun, A; Krolewiecki, A; Laufer, N; Pérez, H; Quarleri, J; Rolón, MJ; Salomón, H | 1 |
| Dauby, N; Dupont, E; Levy, J; Menotti, J; Moens, C; Robberecht, F; Talabani, H; van Gool, T; Vandenberg, O | 1 |
| Hokari, A | 1 |
| El Kassas, M; El Raziky, M; Esmat, G; Gamil, ME; Hassany, M | 1 |
| Bardin, MC; Carrion, ME; Julcamoro, LM; Lopez-Chegne, N; Rossignol, JF | 1 |
| Choi, IS; Hong, SK; Kim, HJ; Lee, JB; Park, SY; Song, CS | 1 |
| Garcia, CV; Gonçalves, HM; Malesuik, MD; Nardi, NB; Schapoval, EE; Steppe, M; Trein, MR | 1 |
| Abdel Salam, RA; Emara, S; Hadad, GM | 1 |
| Ballard, TE; Guerrant, RL; Hoffman, PS; Kennedy, A; Kolling, GL; Macdonald, TL; Olekhnovich, I; Riggins, M; van Opstal, E; Wang, X; Warren, CA; Warthan, M | 1 |
| Andersen, RJ; Anderson, HJ; Av-Gay, Y; Balgi, AD; Forestieri, R; Lam, KK; Nodwell, M; Roberge, M; Vollett, S; Zheng, X | 1 |
| Cheema, FH; Kanwal, S; Korsten, MA; Luthra, M; Majeed, UM; Rafiullah, F; Sohail, MR | 1 |
| Albonico, M; Ali, SM; Alles, R; Ame, SM; Hattendorf, J; Keiser, J; Speich, B; Utzinger, J | 1 |
| Johnson, S; Venugopal, AA | 1 |
| Amir, J; Behor, J; Cleper, R; Dagan, A; Davidovits, M; Krause, I; Samra, Z | 1 |
| Chen, W; Chen, Y; Hu, X; Xie, W; Zhang, L; Zheng, X | 1 |
| Guerrant, RL; Hoffman, PS; Kolling, GL; Li, Y; Moore, JH; Riggins, MS; van Opstal, EJ; Warren, CA | 1 |
| Madrid, EM; Mahanty, S; Nash, TE | 1 |
| Criollo, CP; Granados, CE; Reveiz, L; Uribe, LG | 1 |
| Albonico, M; Ali, SM; Ame, SM; Bogoch, II; Keiser, J; Marti, H; Speich, B; Utzinger, J | 1 |
| Abdou, AG; Afifi, AF; Elnaidany, NF; Harba, NM | 1 |
| Dimmitt, RA; Maclin, J; Thame, KA; Vadlamudi, N | 1 |
| Bassaganya-Riera, J; Bolick, DT; Guerrant, RL; Hontecillas, R; Nataro, JP; Roche, JK | 1 |
| Favennec, L; François, A; Gargala, G; Rossignol, JF | 1 |
| Fitzgerald, DW; Johnson, WD; Merveille, YM; Nathan, CF; Ocheretina, O; Pape, JW; Shigyo, K | 1 |
| Cahn, P; Gun, A; Laufer, N; Ojeda, D; Quarleri, J; Sede, M | 1 |
| Müller, J; Müller, N; Schildknecht, P | 1 |
| Bodapati, S; Fan, A; Fan-Minogue, H; Felsher, DW; Gambhir, SS; Massoud, TF; Paulmurugan, R; Solow-Cordero, D | 1 |
| Baldisserotto, B; Cunha, MA; Gressler, LT; Sutili, FJ; Vargas, AC; Zeppenfeld, CC | 1 |
| Aroian, RV; Ellis, BL; Hu, Y; Miller, MM; Shi, LZ; Urban, JF; Yiu, YY | 1 |
| Deraz, DM; Elbaz, TM; Shehab, HM | 1 |
| Gutwein, MB; Kaleem, Z; Weinstock, LB | 1 |
| Angelini, M; Arnoldi, F; Belardo, G; Burrone, OR; Ciucci, A; Coira, M; Gianferretti, P; La Frazia, S; Rossignol, JF; Santoro, MG | 1 |
| Dueñas Jiménez, JM; Galván-Ramírez, Mde L; García-Iglesias, T; Ramírez-Herrera, M; Rocío Rodríguez Pérez, L; Troyo-Sanroman, R | 1 |
| Drimba, L; Hári, P; Hegedűs, C; Kovács, D; Málnási-Csizmadia, A; Németh, J; Peitl, B; Sári, R; Simon, Z; Szilvássy, Z | 1 |
| Galisteo, AJ; Mesquita, JT; Pinto, EG; Taniwaki, NN; Tempone, AG | 1 |
| Castillo, R; Gres-Molina, J; Hernández-Campos, A; Hernández-Luis, F; Maldonado, LA; Soria-Arteche, O; Trejo-Soto, PJ; Yépez-Mulia, L | 1 |
| Abed, M; Arnold, M; Bissinger, R; Faggio, C; Lang, E; Lang, F; Modicano, P | 1 |
| Mesquita, JT; Reimão, JQ; Tempone, AG | 1 |
| Ellis, J; Harkness, J; Marriott, D; Roberts, T; Stark, D | 1 |
| Abdelkawy, M; El Gindy, AE; Hegazy, M; Kessiba, A | 1 |
| Abdella, OH; Aboshiesha, GA; Abu-Hashim, AH; El-Bader, MM; El-Shemy, AS; Hussien, SM; Taha, MA | 1 |
| Martínez-Tovilla, Y; Mas-Coma, S; Rojas-García, R; Rojas-Rivero, L; Sarracent-Pérez, J; Valero, MA; Zumaquero-Ríos, JL | 1 |
| Charnley, RM; Dronamraju, SS; Jaques, BC; Samuel, JR; Schmid, M | 1 |
| Aroian, RV; Ellis, BL; Hu, Y; Somvanshi, VS | 1 |
| Deng, X; Li, B; Li, S; Ma, Z; Qiu, Y; Shao, D; Shi, Z; Wang, X; Wei, J; Xue, F; Zhang, K | 1 |
| Bessoff, K; Foderaro, JE; Huston, CD; Jumani, RS; Spangenberg, T; Ward, GE | 1 |
| Hotez, PJ | 1 |
| Camm, AJ; Ferber, G; Lorch, U; Rossignol, JF; Täubel, J | 1 |
| Gluud, C; Grevstad, B; Jakobsen, JC; Nikolova, K | 1 |
| Glisoni, RJ; Sosnik, A | 1 |
| Brockmann, A; Brunner, T; Marx, A; May, S; Stemmer, K; Strittmatter, T | 1 |
| Bai, L; Mai, HA; Wang, YH; Zhao, JM | 1 |
| Bardin, M; Ginocchio, C; Haffizulla, J; Hartman, A; Hoppers, M; Resnick, H; Rossignol, JF; Samudrala, S | 1 |
| Bhaskaran, K; Thomas, SL | 1 |
| Bowen, AC; Carapetis, JR; McLeod, C; Morris, PS; Snelling, TL | 1 |
| Ashiru, O; Butters, TD; Howe, JD | 1 |
| Adhikari, S; Hurdle, JG; Kumar, M | 1 |
| Castillo-Villanueva, A; de la Mora-de la Mora, I; Enríquez-Flores, S; Figueroa-Salazar, R; García-Torres, I; Gómez-Manzo, S; Gutiérrez-Castrellón, P; Hernández-Alcántara, G; López-Velázquez, G; Marcial-Quino, J; Méndez, ST; Oria-Hernández, J; Reyes-Vivas, H; Torres-Arroyo, A; Vanoye-Carlo, A; Yépez-Mulia, L | 1 |
| Ali, S; Baqi, S; Kalam, K; Mumar, S; Raja, K | 1 |
| Bardin, MC; Gekonge, B; Montaner, LJ | 1 |
| Belardo, G; Cenciarelli, O; La Frazia, S; Rossignol, JF; Santoro, MG | 1 |
| Cao, J; Forrest, JC; Zhang, X | 1 |
| Boubaker, G; Gorgas, D; Gottstein, B; Hemphill, A; Müller, J; Müller, N; Rufener, R; Spiliotis, M; Stadelmann, B | 1 |
| Johnson, S; Soriano, MM | 1 |
| Ai, N; Welsh, WJ; Wood, RD | 1 |
| Hu, W; Liu, C; Yin, J; Zhang, H | 1 |
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| Costa, TL; de Andrade Picanço, G; Ferreira de Lima, N; Vinaud, MC | 1 |
| Abd-Elsalam, SM; Bahaa, MM; Baiomy, N; Elnaggar, MH; Elsawy, AA; Gamal, RM; Habba, E; Salamah, AM; Shawky, D | 1 |
| Andersson, C; Blom, K; Brechot, C; Ek, F; Fryknäs, M; Jarvius, M; Larsson, R; Nygren, P; Rudfeldt, J; Selvin, T; Senkowski, W | 1 |
| Abd Elghafar, MS; Abd-Elsalam, S; Abdelghaffar, H; Abdelghaffar, K; Al Shafie, A; Badr, M; El-Kassas, M; Esmael, HE; Ezz Eldin, AM; Ezzat, S; Hassany, SM; Kamal, DT; Karam-Allah, H; Medhat, MA; Moaz, I; Moustafa, E; Ossimi, A; Salama, M; Sayed, H; Shamseldeen, A | 1 |
| Akhir, A; Chopra, S; Goel, A; Kaul, G; Rawat, KS; Rode, HB; Sangu, KG; Sharma, CP; Shukla, M | 1 |
| Barthélémy, K; Chatelain, E; Chotsiri, P; Cochin, M; de Lamballerie, X; Driouich, JS; Escudié, F; Fraisse, L; Gilles, M; Hoglund, RM; Laprie, C; Moureau, G; Mowbray, CE; Nougairède, A; Petit, PR; Scandale, I; Sjö, P; Solas, C; Tarning, J; Touret, F; Wattanakul, T | 1 |
| Adom, AA; Aguirre-Alvarado, C; Aguirre-Gil, G; Bekker-Méndez, C; Cortes-Vazquez, MA; Cruz-Carbajal, AS; Dehbi, HM; Delgado-Pastelin, L; Escobedo, J; Favari-Perozzi, L; Gastine, S; González, YSP; Hoyo-Vadillo, C; Lowe, D; Mateos, E; Navarro-Gualito, MD; Owen, A; Smith, T; Standing, J; Villegas-Lara, B | 1 |
| Abdel-Lateef, MA; Abu-Hassan, AA; Almahri, A; Alzahrani, E; El Hamd, MA; Mohammad, BS; Pashameah, RA | 1 |
| Anand, B; Annadure, RK; Arulselvan, V; Deepalam, S; Gupta, S; Ichaporia, N; Iyer, RB; John, SK; Kamath, V; Kumar, S; Mathew, T; Murgod, U; Nadig, R; Nair, SS; Neeharika, ML; Netravathi, M; Parry, G; Raghavendra, S; Reddy, YM; Renukaradhya, U; Rohatgi, A; Sarma, GRK; Satishchandra, P; Sharath Kumar, GG; Shivakumar, R; Singh, P; Singhal, BS; Surya, N; Yareeda, S | 1 |
| Akpomiemie, G; Bosch, B; Casas, CP; Ellis, L; Hill, A; Johnstone, H; Owen, A; Simmons, B; Sokhela, S; Venter, WDF; Woods, J | 1 |
| Barreto-Alves, JA; do Nascimento-Júnior, EM; Fakhouri, R; Ferreira, LC; Martins-Filho, PR | 1 |
| Hemmati-Dinarvand, M; Kheirandish, S; Khodadadian, A; Mostafazadeh, M; Seghatoleslam, A | 1 |
| Auer, M; Bauer, A; Berek, K; Berger, T; Bsteh, G; Deisenhammer, F; Di Pauli, F; Hegen, H; Oftring, A; Reindl, M; Rudzki, D; Zinganell, A | 1 |
| Aydogdu, S; Hatipoglu, A | 1 |
| Chao, CM; Lai, CC; Wang, JH; Weng, TC; Weng, TS | 1 |
| Abla, N; Arbe-Barnes, S; Chandiwana, N; Chughlay, MF; Dineka, Y; Duparc, S; Francois Venter, WD; Hill, A; Johnstone, H; Ju, C; Kim, B; Kruger, C; Marrast, AC; Miller, R; Owen, A; Windgassen, D | 1 |
| Batakoushy, HA; El-Didamoony, MA; Elkady, EF; Mostafa, EA | 1 |
| Bolinger, AA; Chen, H; Li, H; Li, J; Xu, J; Xue, Y; Zhou, J; Zhou, M | 1 |
| Arreguin-Espinosa, R; Baeza-Ramírez, I; Calderón-Jaimes, E; Castillo-Rodríguez, RA; Gómez-Manzo, S; González-Valdez, A; Hernández-Ochoa, B; Martínez-Rosas, V; Morales-Luna, L; Ortega-Cuellar, D; Pérez de la Cruz, V; Rufino-González, Y; Vidal-Limón, A; Wong-Baeza, C | 1 |
63 review(s) available for nitazoxanide and thiazoles
| Article | Year |
|---|---|
Frontiers in anthelmintic pharmacology.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Caenorhabditis elegans; Cattle; Cattle Diseases; Depsipeptides; Diketopiperazines; Drug Resistance; Helminthiasis, Animal; Helminths; Ivermectin; Macrolides; Nitro Compounds; Peptides, Cyclic; Piperazines; Sheep; Sheep Diseases; Thiazoles | 1999 |
[New drugs for treatment of parasitic infections].
Topics: Antiparasitic Agents; Humans; Intestinal Diseases, Parasitic; Leishmaniasis; Nitro Compounds; Phosphorylcholine; Thiazoles | 2003 |
Nitazoxanide treatment for giardiasis and cryptosporidiosis in children.
Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Child; Clinical Trials as Topic; Cryptosporidiosis; Drug Interactions; Giardiasis; Humans; Nitro Compounds; Thiazoles | 2004 |
A review of chemotherapeutic approaches to the treatment of cryptosporidiosis.
Topics: Animals; Biogenic Polyamines; Coccidiostats; Cryptosporidiosis; Cryptosporidium; Humans; Nitro Compounds; Thiazoles; Tubulin | 2003 |
Nitazoxanide: a new broad spectrum antiparasitic agent.
Topics: Animals; Antiparasitic Agents; Cryptosporidiosis; Drug Approval; Giardiasis; Helminthiasis; Humans; Nitro Compounds; Protozoan Infections; Thiazoles; United States | 2004 |
Cryptosporidiosis in children.
Topics: Animals; Child, Preschool; Coccidiostats; Cryptosporidiosis; Cryptosporidium; Female; Humans; Infant; Male; Nitro Compounds; Thiazoles | 2004 |
Use of nitazoxanide as a new therapeutic option for persistent diarrhea: a pediatric perspective.
Topics: Animals; Antiparasitic Agents; Diarrhea, Infantile; Eukaryota; Humans; Infant; Male; Nitro Compounds; Thiazoles | 2005 |
Molecular survival strategies of Echinococcus multilocularis in the murine host.
Topics: 14-3-3 Proteins; Animals; Anticestodal Agents; Echinococcosis, Hepatic; Echinococcus multilocularis; Host-Parasite Interactions; Mice; Mice, Inbred BALB C; Mice, Nude; Nitro Compounds; Thiazoles | 2006 |
Nitazoxanide, a broad-spectrum thiazolide anti-infective agent for the treatment of gastrointestinal infections.
Topics: Animals; Anti-Infective Agents; Gastrointestinal Diseases; Humans; Nitro Compounds; Thiazoles | 2006 |
[Therapeutic alternatives in case of failure of first-line treatment of intestinal helminthiasis in adults].
Topics: Albendazole; Ancylostomiasis; Anthelmintics; Artemether; Artemisinins; Benzimidazoles; Drug Resistance; Fascioliasis; Helminthiasis; Intestinal Diseases, Parasitic; Nitro Compounds; Schistosomiasis; Strongyloidiasis; Taeniasis; Thiazoles; Treatment Failure | 2006 |
Antimicrobial therapy of Clostridium difficile-associated diarrhea.
Topics: Aged; Anti-Infective Agents; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; Disease Outbreaks; Feces; Humans; Infant; Megacolon, Toxic; Metronidazole; Nitro Compounds; Risk Factors; Secondary Prevention; Thiazoles; Vancomycin | 2006 |
Treatment of cryptosporidiosis in immunocompromised individuals: systematic review and meta-analysis.
Topics: Anti-Retroviral Agents; Antiprotozoal Agents; Cryptosporidiosis; Diarrhea; Drug Therapy, Combination; Female; HIV Seronegativity; HIV Seropositivity; Humans; Immunocompromised Host; Male; Nitro Compounds; Opportunistic Infections; Randomized Controlled Trials as Topic; Thiazoles; Treatment Failure | 2007 |
Clostridium difficile: new therapeutic options.
Topics: Animals; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Community-Acquired Infections; Depsipeptides; Diarrhea; Humans; Nitro Compounds; Polymers; Rifampin; Sulfonic Acids; Thiazoles | 2007 |
Nitazoxanide: a review of its use in the treatment of gastrointestinal infections.
Topics: Anti-Infective Agents; Antiparasitic Agents; Bacterial Infections; Gastrointestinal Diseases; Humans; Intestinal Diseases, Parasitic; Nitro Compounds; Thiazoles; Virus Diseases | 2007 |
Part XI. Trimethoprim-sulfamethoxazole, nitrofurantoin, chloramphenicol, metronidazole and tinidazole, rifaximin, and nitazoxanide.
Topics: Anti-Bacterial Agents; Bacterial Infections; Chloramphenicol; Drug Resistance, Microbial; Humans; Metronidazole; Nitro Compounds; Nitrofurantoin; Rifamycins; Rifaximin; Thiazoles; Tinidazole; Trimethoprim, Sulfamethoxazole Drug Combination | 2007 |
[Attention-getting zoonoses: Cryptosporidiosis].
Topics: AIDS-Related Opportunistic Infections; Animals; Antiparasitic Agents; Cryptosporidiosis; Cryptosporidium parvum; Drug Design; Fluid Therapy; Fluorescent Antibody Technique; Humans; Molecular Diagnostic Techniques; Nitro Compounds; Thiazoles; Zoonoses | 2007 |
Thiazolides: a new class of drugs for the treatment of chronic hepatitis B and C.
Topics: Antiviral Agents; Clinical Trials as Topic; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Nitro Compounds; Thiazoles | 2008 |
Drug treatment and novel drug target against Cryptosporidium.
Topics: Animals; Coccidiostats; Cryptosporidiosis; Cryptosporidium; Diarrhea; Disease Outbreaks; Humans; Nitro Compounds; Thiazoles; Treatment Outcome | 2008 |
Treatment of cryptosporidiosis.
Topics: AIDS-Related Opportunistic Infections; Animals; Antiretroviral Therapy, Highly Active; Azithromycin; Biliary Tract Diseases; Coccidiostats; Cryptosporidiosis; Humans; Immunocompromised Host; Nitro Compounds; Paromomycin; Rifamycins; Rifaximin; Thiazoles | 2009 |
Thiazolides: a new class of antiviral drugs.
Topics: Antiviral Agents; Clinical Trials as Topic; Gastroenteritis; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Nitro Compounds; Thiazoles | 2009 |
Hepatitis C virus infection and immunomodulatory therapies.
Topics: Antibodies, Monoclonal; Antiviral Agents; Hepacivirus; Hepatitis C, Chronic; Humans; Immunoglobulins; Immunologic Factors; Immunotherapy; Interferons; Nitro Compounds; Ribavirin; Thiazoles; Toll-Like Receptors; Viral Hepatitis Vaccines | 2009 |
Targeting host factors: a novel rationale for the management of hepatitis C virus.
Topics: Antibodies; Antiviral Agents; Cyclophilins; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Nitro Compounds; Peroxisome Proliferator-Activated Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Receptors, Virus; Thiazoles; Virus Internalization | 2009 |
Human cryptosporidiosis: a review.
Topics: Amebicides; Animals; Anti-Bacterial Agents; Antiparasitic Agents; Classification; Coccidiostats; Cryptosporidiosis; HIV Infections; Humans; Kenya; Nitro Compounds; Paromomycin; Prognosis; Spiramycin; Thiazoles | 2009 |
[Antiviral therapy for chronic hepatitis C: current status and perspectives].
Topics: Antiviral Agents; DNA-Directed RNA Polymerases; Drug Administration Schedule; Drug Discovery; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Nitro Compounds; Oligopeptides; Polyethylene Glycols; Protease Inhibitors; Pyrimidine Nucleosides; Recombinant Proteins; Ribavirin; Thiazoles | 2010 |
[Nitazoxanide ("Alinia")--a promising antiparasitic drug].
Topics: Animals; Antiparasitic Agents; Cestode Infections; Humans; Nematode Infections; Nitro Compounds; Protozoan Infections; Thiazoles; Trematode Infections | 2010 |
Clostridium difficile infection: update on emerging antibiotic treatment options and antibiotic resistance.
Topics: Aminoglycosides; Anti-Bacterial Agents; Clinical Trials, Phase III as Topic; Clostridioides difficile; Clostridium Infections; Drug Resistance, Bacterial; Fidaxomicin; Humans; Microbial Sensitivity Tests; Nitro Compounds; Randomized Controlled Trials as Topic; Rifamycins; Rifaximin; Thiazoles; Treatment Outcome | 2010 |
Treatment of cryptosporidiosis: do we know what we think we know?
Topics: Antiprotozoal Agents; Cryptosporidiosis; Cryptosporidium; HIV Infections; Humans; Immunocompromised Host; Molecular Epidemiology; Nitro Compounds; Thiazoles | 2010 |
New antibiotics for selective treatment of gastrointestinal infection caused by Clostridium difficile.
Topics: Aminoglycosides; Anti-Bacterial Agents; Benzopyrans; Clostridioides difficile; Enterocolitis, Pseudomembranous; Fidaxomicin; Glycopeptides; Humans; Lipoglycopeptides; Nitro Compounds; Thiazoles; Thiophenes | 2010 |
Evaluation of nitazoxanide for the treatment of disseminated cystic echinococcosis: report of five cases and literature review.
Topics: Adult; Aged; Albendazole; Animals; Anthelmintics; Drug Therapy, Combination; Echinococcosis; Echinococcus granulosus; Female; Humans; Male; Middle Aged; Nitro Compounds; Praziquantel; Thiazoles; Treatment Outcome | 2011 |
Cryptosporidiosis: a rare and severe infection in a pediatric renal transplant recipient.
Topics: Child; Coccidiostats; Cryptosporidiosis; Drug Therapy, Combination; Humans; Kidney Transplantation; Male; Nitro Compounds; Paromomycin; Postoperative Complications; Spiramycin; Thiazoles | 2012 |
Treatment and prevention of cryptosporidiosis: what options are there for a country like Zambia?
Topics: Antiprotozoal Agents; Cryptosporidiosis; Cryptosporidium; Diarrhea; Drinking Water; HIV Infections; Humans; Immunocompromised Host; Nitro Compounds; Paromomycin; Thiazoles; Water Purification; Zambia | 2011 |
Use of alternative or adjuvant pharmacologic treatment strategies in the prevention and treatment of Clostridium difficile infection.
Topics: Aminoglycosides; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Immunotherapy; Nitro Compounds; Polymers; Probiotics; Thiazoles | 2011 |
[Improved virologic response in chronic hepatitis C treated with peginterferon, ribavirin and add-on drug].
Topics: Antiviral Agents; Cyclosporine; Diterpenes; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fatty Alcohols; Female; Fluvastatin; Hepatitis C, Chronic; Humans; Indoles; Interferon-alpha; Male; Metformin; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Silybin; Silymarin; Thiazoles | 2011 |
The future for the treatment of genotype 4 chronic hepatitis C.
Topics: Albumins; Antiviral Agents; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Nitro Compounds; Oligopeptides; Polyethylene Glycols; Proline; Recombinant Proteins; Ribavirin; Serine Proteinase Inhibitors; Thiazoles; Time Factors; Viral Load; Vitamin D | 2012 |
Current state of Clostridium difficile treatment options.
Topics: Anti-Bacterial Agents; Bacitracin; Clinical Trials as Topic; Clostridioides difficile; Clostridium Infections; Drug Resistance, Bacterial; Fusidic Acid; Humans; Metronidazole; Nitro Compounds; Secondary Prevention; Severity of Illness Index; Teicoplanin; Thiazoles; Treatment Outcome; Vancomycin | 2012 |
Drugs for treating giardiasis.
Topics: Adult; Albendazole; Antiparasitic Agents; Child; Giardiasis; Humans; Mebendazole; Metronidazole; Nitro Compounds; Randomized Controlled Trials as Topic; Thiazoles; Tinidazole | 2012 |
Nitazoxanide for chronic hepatitis C.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Cause of Death; Hepatitis C, Chronic; Humans; Nitro Compounds; Randomized Controlled Trials as Topic; Thiazoles | 2014 |
Nitazoxanide: a first-in-class broad-spectrum antiviral agent.
Topics: Antiparasitic Agents; Antiviral Agents; DNA Virus Infections; Drug Repositioning; Humans; Influenza, Human; Nitro Compounds; Thiazoles; Virus Replication | 2014 |
Treatment of echinococcosis: albendazole and mebendazole--what else?
Topics: Albendazole; Animals; Anthelmintics; Cell Division; Clarithromycin; Cytostatic Agents; Drug Design; Drug Evaluation, Preclinical; Echinococcosis; Echinococcosis, Hepatic; Echinococcus multilocularis; Forecasting; Guanidines; Helminth Proteins; Host-Parasite Interactions; Humans; Imidazoles; Larva; Mebendazole; Mefloquine; Mice; Molecular Targeted Therapy; Nitro Compounds; Thiazoles; Thiophenes | 2014 |
Treatment of Clostridium difficile infections.
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Drug Administration Schedule; Drug Therapy, Combination; Fidaxomicin; Gastrointestinal Diseases; Humans; Metronidazole; Nitro Compounds; Randomized Controlled Trials as Topic; Recurrence; Rifamycins; Rifaximin; Thiazoles; Vancomycin | 2015 |
A functional perspective of nitazoxanide as a potential anticancer drug.
Topics: Animals; Antineoplastic Agents; Antiparasitic Agents; Cell Proliferation; Cell Survival; Humans; Neoplasms; Nitro Compounds; Proto-Oncogene Proteins c-myc; Signal Transduction; Stromal Cells; Thiazoles; Unfolded Protein Response | 2014 |
Cryptosporidium and Giardia in Africa: current and future challenges.
Topics: Africa; Animals; Antiprotozoal Agents; Child; Climate Change; Cost of Illness; Cryptosporidiosis; Cryptosporidium; Diarrhea; Disease Management; Feces; Genotyping Techniques; Giardia; Giardiasis; Humans; Nitro Compounds; Prevalence; Public Health; Thiazoles; Zoonoses | 2017 |
Update on Nitazoxanide: A Multifunctional Chemotherapeutic Agent.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Humans; Nitro Compounds; Thiazoles | 2018 |
Novel treatment strategies and drugs in development for cryptosporidiosis.
Topics: Animals; Antiprotozoal Agents; Clofazimine; Cryptosporidiosis; Diarrhea; Drug Development; Global Health; Humans; Immunocompromised Host; Mice; Nitro Compounds; Thiazoles | 2018 |
Treatment interventions for diarrhoea in HIV-infected and HIV-exposed children: a systematic review.
Topics: Adolescent; Anti-HIV Agents; Antiparasitic Agents; Child; Child, Preschool; Cryptosporidiosis; Diarrhea; Dietary Supplements; Drug Interactions; HIV Infections; Humans; Micronutrients; Nitro Compounds; Randomized Controlled Trials as Topic; Thiazoles | 2018 |
Efficacy of 5-nitroimidazole compounds for giardiasis in Cuban children: systematic review and meta-analysis.
Topics: Antiprotozoal Agents; Benzimidazoles; Child; Chloroquine; Cuba; Giardiasis; Humans; Nitro Compounds; Nitroimidazoles; Paromomycin; Randomized Controlled Trials as Topic; Thiazoles; Tinidazole; Treatment Outcome | 2019 |
The Microbial Toxin Microcin B17: Prospects for the Development of New Antibacterial Agents.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacteria; Bacteriocins; Cinoxacin; DNA Cleavage; DNA Gyrase; Drug Development; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Humans; Mutation; Nitro Compounds; Peptides; Protein Processing, Post-Translational; Thiazoles; Toxins, Biological | 2019 |
Nitazoxanide in the Treatment of Intestinal Parasitic Infections in Children: A Systematic Review and Meta-Analysis.
Topics: Child; Databases, Factual; Diarrhea; Humans; Nitro Compounds; Parasitic Diseases; Thiazoles | 2020 |
Treatment of
Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Nitro Compounds; Proton Pump Inhibitors; Thiazoles; Treatment Outcome | 2020 |
Helicobacter pylori: A Review of Current Diagnostic and Management Strategies.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antigens, Bacterial; Biopsy; Bismuth; Breath Tests; Clarithromycin; Culture Techniques; Doxycycline; Drug Resistance, Bacterial; Drug Therapy, Combination; Dyspepsia; Feces; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Lymphoma, B-Cell, Marginal Zone; Metronidazole; Nitro Compounds; Organometallic Compounds; Peptic Ulcer; Polymerase Chain Reaction; Proton Pump Inhibitors; Rifabutin; Salicylates; Salvage Therapy; Serologic Tests; Stomach Neoplasms; Tetracycline; Thiazoles; Treatment Outcome; Urea | 2020 |
Review of Emerging Pharmacotherapy for the Treatment of Coronavirus Disease 2019.
Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Antibodies, Monoclonal, Humanized; Antiviral Agents; Azetidines; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Drug Combinations; Humans; Hydroxychloroquine; Immunization, Passive; Immunomodulation; Interferon-alpha; Lopinavir; Nelfinavir; Nitro Compounds; Pandemics; Pneumonia, Viral; Purines; Pyrazoles; Ribavirin; Ritonavir; SARS-CoV-2; Sulfonamides; Thiazoles | 2020 |
Antiviral treatment of COVID-19
Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Combinations; Humans; Hydroxychloroquine; Ivermectin; Lopinavir; Nitro Compounds; Pandemics; Pneumonia, Viral; Pyrazines; Ritonavir; SARS-CoV-2; Thiazoles | 2020 |
Mysterious Virus: A Review on Behavior and Treatment Approaches of the Novel Coronavirus, 2019-nCoV.
Topics: Betacoronavirus; Coronavirus Infections; COVID-19; Disease Outbreaks; Humans; Nitro Compounds; Pandemics; Pneumonia, Viral; SARS-CoV-2; Thiazoles | 2020 |
Effect of nitazoxanide on diarrhea: A systematic review and network meta-analysis of randomized controlled trials.
Topics: Animals; Clostridium Infections; Cryptosporidiosis; Diarrhea; Entamoebiasis; Giardia lamblia; Giardiasis; Humans; Network Meta-Analysis; Nitro Compounds; Thiazoles | 2020 |
A review on possible mechanistic insights of Nitazoxanide for repurposing in COVID-19.
Topics: Antiprotozoal Agents; Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Humans; Immunity, Innate; Nitro Compounds; SARS-CoV-2; Thiazoles | 2021 |
Possible treatment and strategies for COVID-19: review and assessment.
Topics: Adenosine Monophosphate; Alanine; Amides; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antibodies, Neutralizing; Antiparasitic Agents; Antiviral Agents; Cannabinoids; Chloroquine; Complement Inactivating Agents; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; COVID-19 Vaccines; Dexamethasone; Drug Combinations; Enzyme Inhibitors; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Interferons; Ivermectin; Lopinavir; Nitro Compounds; Pyrazines; Ritonavir; SARS-CoV-2; Teicoplanin; Tetracyclines; Thiazoles | 2020 |
Antiviral treatment in COVID-19: which is the most promising?-a narrative review.
Topics: Adenosine Monophosphate; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; Azetidines; Chloroquine; COVID-19; COVID-19 Serotherapy; Drug Combinations; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Interferons; Ivermectin; Lopinavir; Nitro Compounds; Oseltamivir; Purines; Pyrazines; Pyrazoles; Ribavirin; Ritonavir; Sulfonamides; Thiazoles | 2021 |
Use-case scenarios for an anti-Cryptosporidium therapeutic.
Topics: Antiparasitic Agents; Child, Preschool; Cryptosporidiosis; Cryptosporidium; Diarrhea; Disease Outbreaks; Fluid Therapy; Humans; Immunocompromised Host; Infant; Infant, Newborn; Nitro Compounds; Thiazoles | 2021 |
Interventions in an Ambulatory Setting to Prevent Progression to Severe Disease in Patients With COVID-19: A Systematic Review.
Topics: Ambulatory Care; Antibodies, Monoclonal, Humanized; Antibodies, Neutralizing; Antiviral Agents; COVID-19; Disease Progression; Humans; Interferons; Ivermectin; Nitro Compounds; Polyethylene Glycols; Thiazoles | 2022 |
Role of nitazoxanide as a repurposed drug in the treatment and management of various diseases.
Topics: Anti-Bacterial Agents; Child; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Nitro Compounds; Pharmaceutical Preparations; Thiazoles | 2021 |
Efficacy and safety of nitazoxanide in treating SARS-CoV-2 infection: a systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials.
Topics: Anti-Inflammatory Agents; Antiparasitic Agents; Antiviral Agents; COVID-19 Drug Treatment; Disease Progression; Humans; Lactate Dehydrogenases; Nitro Compounds; Randomized Controlled Trials as Topic; SARS-CoV-2; Thiazoles | 2022 |
Clinical outcomes, virological efficacy and safety of nitazoxanide in the treatment of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials.
Topics: COVID-19 Drug Treatment; Humans; Nitro Compounds; Randomized Controlled Trials as Topic; Thiazoles | 2022 |
Therapeutic potential of salicylamide derivatives for combating viral infections.
Topics: Antiviral Agents; COVID-19; Humans; Nitro Compounds; Salicylamides; Thiazoles; Virus Replication | 2023 |
75 trial(s) available for nitazoxanide and thiazoles
| Article | Year |
|---|---|
Pharmacokinetics of nitazoxanide after single oral dose administration in 6 healthy volunteers.
Topics: Administration, Oral; Adult; Antiprotozoal Agents; Humans; Male; Nitro Compounds; Thiazoles | 1996 |
Nitazoxanide in the treatment of cryptosporidial diarrhea and other intestinal parasitic infections associated with acquired immunodeficiency syndrome in tropical Africa.
Topics: AIDS-Related Opportunistic Infections; Animals; Antiprotozoal Agents; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; Humans; Intestinal Diseases, Parasitic; Mali; Nitro Compounds; Thiazoles | 1997 |
Nitazoxanide: pharmacokinetics and metabolism in man.
Topics: Administration, Oral; Adult; Antiprotozoal Agents; Carbon Radioisotopes; Half-Life; Humans; Male; Middle Aged; Nitro Compounds; Thiazoles; Tissue Distribution | 2000 |
Cryptosporidiosis in Benha, study of some recent modalities in diagnosis and treatment.
Topics: Adolescent; Adult; Anti-Infective Agents; Child; Child, Preschool; Cryptosporidiosis; Diarrhea; Egypt; Female; Fluorescent Antibody Technique, Direct; Humans; Infant; Male; Nitro Compounds; Prevalence; Sensitivity and Specificity; Thiazoles; Trimethoprim, Sulfamethoxazole Drug Combination | 2000 |
NTZ for cryptosporidiosis.
Topics: Antiprotozoal Agents; Cryptosporidiosis; HIV Infections; Humans; Nitro Compounds; Randomized Controlled Trials as Topic; Thiazoles | 1996 |
AIDS patients sought for study with NTZ for cryptosporidiosis.
Topics: AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Cryptosporidiosis; Double-Blind Method; Humans; Nitro Compounds; Patient Selection; Placebos; Thiazoles | 1997 |
Treatment of diarrhea caused by Cryptosporidium parvum: a prospective randomized, double-blind, placebo-controlled study of Nitazoxanide.
Topics: Adolescent; Adult; Aged; Animals; Antiprotozoal Agents; Child; Child, Preschool; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; Double-Blind Method; Drug Administration Schedule; Feces; Female; Humans; Infant; Male; Middle Aged; Nitro Compounds; Prospective Studies; Thiazoles | 2001 |
Treatment of diarrhea caused by Giardia intestinalis and Entamoeba histolytica or E. dispar: a randomized, double-blind, placebo-controlled study of nitazoxanide.
Topics: Adolescent; Adult; Aged; Animals; Antiprotozoal Agents; Child; Diarrhea; Double-Blind Method; Dysentery, Amebic; Entamoeba; Entamoeba histolytica; Entamoebiasis; Feces; Female; Giardia lamblia; Giardiasis; Humans; Male; Middle Aged; Nitro Compounds; Placebos; Thiazoles | 2001 |
Randomized clinical study of nitazoxanide compared to metronidazole in the treatment of symptomatic giardiasis in children from Northern Peru.
Topics: Anti-Infective Agents; Child; Child, Preschool; Diarrhea; Drug Administration Schedule; Female; Giardiasis; Humans; Male; Metronidazole; Nitro Compounds; Peru; Thiazoles; Treatment Outcome | 2001 |
Nitazoxanide pharmacokinetics and tolerability in man using single ascending oral doses.
Topics: Administration, Oral; Adult; Antiparasitic Agents; Area Under Curve; Food-Drug Interactions; Humans; Male; Maximum Tolerated Dose; Nitro Compounds; Thiazoles | 2002 |
Nitazoxanide pharmacokinetics and tolerability in man during 7 days dosing with 0.5 g and 1 g b.i.d.
Topics: Administration, Oral; Adult; Antiparasitic Agents; Area Under Curve; Double-Blind Method; Drug Administration Schedule; Half-Life; Humans; Male; Middle Aged; Nitro Compounds; Thiazoles | 2002 |
Nitazoxanide compared with quinfamide and mebendazole in the treatment of helminthic infections and intestinal protozoa in children.
Topics: Antiparasitic Agents; Child; Child, Preschool; Double-Blind Method; Female; Humans; Intestinal Diseases, Parasitic; Male; Mebendazole; Nematode Infections; Nitro Compounds; Protozoan Infections; Quinolines; Thiazoles; Treatment Outcome | 2002 |
Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis: a randomised controlled trial.
Topics: Antiprotozoal Agents; Child, Preschool; Cryptosporidiosis; Diarrhea; Female; HIV Seronegativity; HIV Seropositivity; Humans; Infant; Male; Nitro Compounds; Nutritional Status; Thiazoles; Treatment Outcome; Zambia | 2002 |
Double-blind, randomized, placebo-controlled study of nitazoxanide in the treatment of fascioliasis in adults and children from northern Peru.
Topics: Antiprotozoal Agents; Child; Child, Preschool; Double-Blind Method; Fascioliasis; Female; Humans; Male; Nitro Compounds; Thiazoles; Treatment Outcome | 2003 |
Nitazoxanide in treatment of Helicobacter pylori: a clinical and in vitro study.
Topics: Adult; Aged; Anti-Infective Agents; Biotransformation; Breath Tests; Drug Therapy, Combination; Enzyme Inhibitors; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Nitro Compounds; Proton Pump Inhibitors; Thiazoles; Urea | 2003 |
Nitazoxanide for persistent diarrhoea in Zambian acquired immune deficiency syndrome patients: a randomized-controlled trial.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Antiparasitic Agents; Bacterial Infections; CD4 Lymphocyte Count; Chronic Disease; Diarrhea; Double-Blind Method; Female; Humans; Intestinal Diseases, Parasitic; Male; Nitro Compounds; Thiazoles | 2005 |
Effect of nitazoxanide in persistent diarrhea and enteritis associated with Blastocystis hominis.
Topics: Adolescent; Adult; Animals; Antiparasitic Agents; Blastocystis hominis; Blastocystis Infections; Child; Diarrhea; Double-Blind Method; Enteritis; Female; Humans; Male; Nitro Compounds; Prospective Studies; Thiazoles; Treatment Outcome | 2005 |
Effect of nitazoxanide in diarrhea and enteritis caused by Cryptosporidium species.
Topics: Administration, Oral; Adult; Antiparasitic Agents; Cryptosporidiosis; Diarrhea; Double-Blind Method; Enteritis; Humans; Nitro Compounds; Prospective Studies; Suspensions; Tablets; Thiazoles; Treatment Outcome | 2006 |
Effect of nitazoxanide for treatment of severe rotavirus diarrhoea: randomised double-blind placebo-controlled trial.
Topics: Anti-Infective Agents; Cell Survival; Cells, Cultured; Child; Child, Preschool; Diarrhea; Double-Blind Method; Female; Gastroenteritis; Hospitalization; Humans; Infant; Male; Nitro Compounds; Rotavirus Infections; Thiazoles; Treatment Outcome | 2006 |
Nitazoxanide for the treatment of Clostridium difficile colitis.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Male; Metronidazole; Nitro Compounds; Thiazoles | 2006 |
Nitazoxanide in the treatment of acquired immune deficiency syndrome-related cryptosporidiosis: results of the United States compassionate use program in 365 patients.
Topics: Adolescent; Adult; Age Distribution; Aged; AIDS-Related Opportunistic Infections; Antiparasitic Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Cryptosporidiosis; Diarrhea; Feces; Female; Humans; Male; Middle Aged; Nitro Compounds; Sex Distribution; Thiazoles; Time Factors; Treatment Outcome; United States | 2006 |
Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial.
Topics: Adolescent; Adult; Anti-Infective Agents; Diarrhea; Double-Blind Method; Gastroenteritis; Humans; Middle Aged; Nitro Compounds; Thiazoles; Treatment Outcome; Virus Diseases | 2006 |
Clostridium difficile colitis that fails conventional metronidazole therapy: response to nitazoxanide.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Male; Metronidazole; Middle Aged; Nitro Compounds; Recurrence; Thiazoles; Treatment Failure | 2007 |
Nitazoxanide in the treatment of amoebiasis.
Topics: Adolescent; Adult; Amebicides; Animals; Child; Child, Preschool; Double-Blind Method; Dysentery, Amebic; Entamoeba histolytica; Female; Humans; Infant; Liver Diseases, Parasitic; Male; Middle Aged; Nitro Compounds; Prospective Studies; Thiazoles; Treatment Outcome | 2007 |
Efficacy of nitazoxanide against experimental cryptosporidiosis in goat neonates.
Topics: Animals; Animals, Newborn; Antiparasitic Agents; Cryptosporidiosis; Feces; Female; Goat Diseases; Goats; Male; Nitro Compounds; Thiazoles | 2007 |
Successful treatment of niclosamide- and praziquantel-resistant beef tapeworm infection with nitazoxanide.
Topics: Adolescent; Adult; Aged; Animals; Antiparasitic Agents; Child; Child, Preschool; Drug Resistance; Endemic Diseases; Female; Humans; India; Male; Middle Aged; Nitro Compounds; Prospective Studies; Taenia saginata; Taeniasis; Thiazoles | 2008 |
Bioequivalence study of a fixed dose combination of nitazoxanide and ofloxacin in Indian healthy volunteers.
Topics: Adult; Anti-Infective Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Drug Combinations; Half-Life; Humans; Male; Nitro Compounds; Ofloxacin; Spectrophotometry, Ultraviolet; Tablets; Therapeutic Equivalency; Thiazoles | 2007 |
The treatment of giardiasis in children: single-dose tinidazole compared with 3 days of nitazoxanide.
Topics: Abdominal Pain; Adolescent; Antiparasitic Agents; Child; Child, Preschool; Cuba; Diarrhea; Feces; Female; Giardiasis; Humans; Nitro Compounds; Thiazoles; Tinidazole; Treatment Outcome | 2008 |
Clinical trial: randomized, double-blind, placebo-controlled study of nitazoxanide monotherapy for the treatment of patients with chronic hepatitis C genotype 4.
Topics: Adult; Aged; Antiviral Agents; Double-Blind Method; Egypt; Female; Genotype; Hepatitis C, Chronic; Humans; Male; Middle Aged; Nitro Compounds; Risk Factors; RNA, Viral; Tablets; Thiazoles; Treatment Outcome | 2008 |
Nitazoxanide for severe cryptosporidial diarrhea in human immunodeficiency virus infected children.
Topics: AIDS-Related Opportunistic Infections; Animals; Child, Preschool; Coccidiostats; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; Humans; Infant; Nitro Compounds; Thiazoles | 2008 |
Prophylactic and therapeutic efficacy of nitazoxanide against Cryptosporidium parvum in experimentally challenged neonatal calves.
Topics: Animals; Animals, Newborn; Antiparasitic Agents; Cattle; Cryptosporidiosis; Cryptosporidium parvum; Nitro Compounds; Thiazoles | 2009 |
Nitazoxanide vs. probiotics for the treatment of acute rotavirus diarrhea in children: a randomized, single-blind, controlled trial in Bolivian children.
Topics: Antiviral Agents; Bolivia; Child; Child, Preschool; Diarrhea; Drug Therapy, Combination; Fluid Therapy; Humans; Infant; Nitro Compounds; Probiotics; Rotavirus Infections; Single-Blind Method; Thiazoles | 2009 |
Nitazoxanide versus vancomycin in Clostridium difficile infection: a randomized, double-blind study.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Double-Blind Method; Enterocolitis, Pseudomembranous; Female; Humans; Male; Middle Aged; Nitro Compounds; Prospective Studies; Thiazoles; Treatment Outcome; United States; Vancomycin | 2009 |
Improved virologic response in chronic hepatitis C genotype 4 treated with nitazoxanide, peginterferon, and ribavirin.
Topics: Adult; Antiparasitic Agents; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Thiazoles; Treatment Outcome; Young Adult | 2009 |
Evaluation of nitazoxanide and oxfendazole efficacy against cystic echinococcosis in naturally infected sheep.
Topics: Animals; Antiparasitic Agents; Benzimidazoles; Echinococcosis, Hepatic; Echinococcosis, Pulmonary; Female; Nitro Compounds; Sheep; Sheep Diseases; Thiazoles | 2009 |
Effect of nitazoxanide on cryptosporidiosis in experimentally infected neonatal dairy calves.
Topics: Animals; Animals, Newborn; Antiparasitic Agents; Cattle; Cattle Diseases; Cryptosporidiosis; Dairying; Feces; Kaplan-Meier Estimate; Male; Nitro Compounds; Oocysts; Thiazoles | 2009 |
Effects of nitazoxanide on pharmacokinetics and pharmacodynamics of a single dose of warfarin.
Topics: Adolescent; Adult; Antiparasitic Agents; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Humans; Male; Middle Aged; Nitro Compounds; Thiazoles; Warfarin | 2009 |
High dose prolonged treatment with nitazoxanide is not effective for cryptosporidiosis in HIV positive Zambian children: a randomised controlled trial.
Topics: Antiparasitic Agents; Child, Preschool; Cryptosporidiosis; Double-Blind Method; Female; HIV Seropositivity; Humans; Infant; Male; Nitro Compounds; Thiazoles; Treatment Outcome; Zambia | 2009 |
Evaluation of nitazoxanide for the treatment of disseminated cystic echinococcosis: report of five cases and literature review.
Topics: Adult; Aged; Albendazole; Animals; Anthelmintics; Drug Therapy, Combination; Echinococcosis; Echinococcus granulosus; Female; Humans; Male; Middle Aged; Nitro Compounds; Praziquantel; Thiazoles; Treatment Outcome | 2011 |
A controlled study of nitazoxanide (NTZ) 3 years after treatment of hepatitis C genotype 4.
Topics: Adult; Aged; Antiviral Agents; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Middle Aged; Nitro Compounds; RNA, Viral; Thiazoles | 2011 |
A randomized study comparing levofloxacin, omeprazole, nitazoxanide, and doxycycline versus triple therapy for the eradication of Helicobacter pylori.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Doxycycline; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Intention to Treat Analysis; Lansoprazole; Levofloxacin; Male; Middle Aged; Nitro Compounds; Ofloxacin; Omeprazole; Prospective Studies; Proton Pump Inhibitors; Recurrence; Thiazoles; Young Adult | 2011 |
Nitazoxanide for the empiric treatment of pediatric infectious diarrhea.
Topics: Antiparasitic Agents; Child; Child, Preschool; Diarrhea; Double-Blind Method; Female; Gastroenteritis; Giardia lamblia; Hispanic or Latino; Humans; Infant; Male; Nitro Compounds; Peru; Thiazoles; Treatment Outcome | 2012 |
Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection: a randomized controlled trial.
Topics: Administration, Oral; Adolescent; Albendazole; Animals; Anthelmintics; Child; Double-Blind Method; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Nitro Compounds; Parasite Egg Count; Placebos; Tanzania; Thiazoles; Treatment Outcome; Trichuriasis; Trichuris | 2012 |
Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide and albendazole-nitazoxanide.
Topics: Adolescent; Albendazole; Antiprotozoal Agents; Blastocystis hominis; Child; Entamoeba histolytica; Feces; Gastrointestinal Diseases; Giardia lamblia; Humans; Indian Ocean Islands; Nitro Compounds; Parasitic Diseases; Parasitology; Placebos; Prevalence; Schools; Thiazoles; Treatment Outcome | 2013 |
The use of nitazoxanide against the pathogens Ichthyophthirius multifiliis and Aeromonas hydrophila in silver catfish (Rhamdia quelen).
Topics: Aeromonas hydrophila; Animals; Anti-Bacterial Agents; Antiparasitic Agents; Catfishes; Ciliophora Infections; Fish Diseases; Gram-Negative Bacterial Infections; Hymenostomatida; Nitro Compounds; Thiazoles | 2013 |
Nitazoxanide plus pegylated interferon and ribavirin in the treatment of genotype 4 chronic hepatitis C, a randomized controlled trial.
Topics: Drug Therapy, Combination; Egypt; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Logistic Models; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Statistics, Nonparametric; Thiazoles | 2014 |
Analyzing the relationship of QT interval and exposure to nitazoxanide, a prospective candidate for influenza antiviral therapy--A formal TQT study.
Topics: Adolescent; Adult; Antiviral Agents; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Influenza, Human; Male; Middle Aged; Nitro Compounds; Thiazoles; Young Adult | 2014 |
Effect of nitazoxanide in adults and adolescents with acute uncomplicated influenza: a double-blind, randomised, placebo-controlled, phase 2b/3 trial.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Infective Agents; Child; Double-Blind Method; Female; Humans; Influenza, Human; Male; Middle Aged; Nitro Compounds; Thiazoles; Young Adult | 2014 |
Impact of nitazoxanide on sustained virologic response in Egyptian patients with chronic hepatitis C genotype 4: a double-blind placebo-controlled trial.
Topics: Adult; Antiparasitic Agents; Antiviral Agents; Double-Blind Method; Drug Therapy, Combination; Egypt; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Thiazoles; Viral Load | 2016 |
Low Efficacy of Pegylated Interferon plus Ribavirin plus Nitazoxanide for HCV Genotype 4 and HIV Coinfection.
Topics: Adult; Antiviral Agents; Coinfection; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Nitro Compounds; Pilot Projects; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Thiazoles; Treatment Outcome | 2015 |
Interferon Stimulated Gene Expression in HIV/HCV Coinfected Patients Treated with Nitazoxanide/Peginterferon-Alfa-2a and Ribavirin.
Topics: Adult; Antiviral Agents; Coinfection; Female; Gene Expression Profiling; Hepatitis C, Chronic; HIV Infections; Humans; Immunologic Factors; Interferon-alpha; Interferons; Leukocytes, Mononuclear; Male; Middle Aged; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Thiazoles | 2016 |
A 2-week Nitazoxanide-based quadruple treatment as a rescue therapy for Helicobacter pylori eradication: A single center experience.
Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Helicobacter Infections; Helicobacter pylori; Humans; Male; Nitro Compounds; Omeprazole; Proton Pump Inhibitors; Retrospective Studies; Thiazoles; Treatment Outcome | 2016 |
Randomized controlled study of a novel triple nitazoxanide (NTZ)-containing therapeutic regimen versus the traditional regimen for eradication of Helicobacter pylori infection.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Drug Therapy, Combination; Egypt; Feces; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Nitro Compounds; Proton Pump Inhibitors; Thiazoles; Treatment Outcome; Young Adult | 2017 |
The NICE-GUT trial protocol: a randomised, placebo controlled trial of oral nitazoxanide for the empiric treatment of acute gastroenteritis among Australian Aboriginal children.
Topics: Antiparasitic Agents; Australia; Child, Preschool; Clinical Protocols; Double-Blind Method; Female; Gastroenteritis; Humans; Infant; Male; Native Hawaiian or Other Pacific Islander; Nitro Compounds; Thiazoles; Treatment Outcome | 2018 |
A Randomized Controlled Trial Comparing Nitazoxanide Plus Lactulose With Lactulose Alone in Treatment of Overt Hepatic Encephalopathy.
Topics: Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Male; Middle Aged; Nitro Compounds; Thiazoles; Treatment Outcome | 2019 |
Early Life Interventions for Childhood Growth and Development in Tanzania (ELICIT): a protocol for a randomised factorial, double-blind, placebo-controlled trial of azithromycin, nitazoxanide and nicotinamide.
Topics: Administration, Oral; Anti-Bacterial Agents; Antiparasitic Agents; Azithromycin; Breast Feeding; Double-Blind Method; Female; Growth and Development; Humans; Infant; Infant, Newborn; Male; Mothers; Niacinamide; Nitro Compounds; Randomized Controlled Trials as Topic; Tanzania; Thiazoles; Vitamin B Complex | 2018 |
ASSESSING THE EFFICACY OF NITAZOXANIDE IN TREATMENT OF CRYPTOSPORIDIOSIS USING PCR EXAMINATION.
Topics: Antiparasitic Agents; Child; Child, Preschool; Cryptosporidiosis; Diarrhea; Female; Humans; Immunocompromised Host; Infant; Male; Nitro Compounds; Polymerase Chain Reaction; Thiazoles | 2016 |
Efficacy and Safety of Nitazoxanide in Addition to Standard of Care for the Treatment of Severe Acute Respiratory Illness.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Child; Child, Preschool; Double-Blind Method; Female; Hospitalization; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nitro Compounds; Oseltamivir; Severe Acute Respiratory Syndrome; Thiazoles; Treatment Outcome; Young Adult; Zanamivir | 2019 |
Treatment with Hydroxychloroquine vs Hydroxychloroquine + Nitazoxanide in COVID-19 patients with risk factors for poor prognosis: A structured summary of a study protocol for a randomised controlled trial.
Topics: Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Therapy, Combination; Humans; Hydroxychloroquine; Nitro Compounds; Pandemics; Pneumonia, Viral; Prognosis; Randomized Controlled Trials as Topic; Respiration, Artificial; Risk Factors; SARS-CoV-2; Single-Blind Method; Thiazoles | 2020 |
Baseline Characteristics of Study Participants in the Early Life Interventions for Childhood Growth and Development in Tanzania (ELICIT) Trial.
Topics: Adult; Azithromycin; Body Weight; Child Health; Child Nutrition Disorders; Child, Preschool; Cohort Studies; Early Medical Intervention; Female; Humans; Infant; Infant, Newborn; Male; Mothers; Neonatal Sepsis; Niacinamide; Nitro Compounds; Poverty; Respiratory Tract Infections; Rural Population; Seasons; Surveys and Questionnaires; Tanzania; Thiazoles; Young Adult | 2020 |
Nitazoxanide against COVID-19 in three explorative scenarios.
Topics: Adult; Ambulatory Care; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Female; Follow-Up Studies; Hospitalization; Humans; Male; Mexico; Nitro Compounds; Pandemics; Pneumonia, Viral; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; SARS-CoV-2; Thiazoles; Treatment Outcome | 2020 |
Intestinal protozoa and helminths in ulcerative colitis and the influence of anti-parasitic therapy on the course of the disease.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiparasitic Agents; Blastocystis; Blastocystis Infections; Colitis, Ulcerative; Drug Therapy, Combination; Female; Giardia lamblia; Humans; Intestines; Male; Mesalamine; Middle Aged; Nitro Compounds; Prevalence; Thiazoles; Treatment Outcome; Young Adult | 2021 |
Early use of nitazoxanide in mild COVID-19 disease: randomised, placebo-controlled trial.
Topics: Adult; COVID-19; Humans; Nitro Compounds; SARS-CoV-2; Thiazoles; Treatment Outcome | 2021 |
Efficacy and safety of nitazoxanide plus atazanavir/ritonavir for the treatment of moderate to severe COVID-19 (NACOVID): A structured summary of a study protocol for a randomised controlled trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antiviral Agents; Atazanavir Sulfate; Clinical Trials, Phase II as Topic; COVID-19; COVID-19 Drug Treatment; COVID-19 Nucleic Acid Testing; Drug Administration Schedule; Drug Combinations; Drug Repositioning; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Nigeria; Nitro Compounds; Pilot Projects; Randomized Controlled Trials as Topic; Ritonavir; RNA, Viral; SARS-CoV-2; Severity of Illness Index; Standard of Care; Thiazoles; Treatment Outcome; Viral Load; Young Adult | 2021 |
Effect of a combination of nitazoxanide, ribavirin, and ivermectin plus zinc supplement (MANS.NRIZ study) on the clearance of mild COVID-19.
Topics: Adult; Antimetabolites; Antiparasitic Agents; COVID-19 Drug Treatment; Female; Humans; Ivermectin; Male; Nitro Compounds; Ribavirin; SARS-CoV-2; Thiazoles; Trace Elements; Zinc | 2021 |
Nitazoxanide versus rifaximin in preventing the recurrence of hepatic encephalopathy: A randomized double-blind controlled trial.
Topics: Child; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Nitro Compounds; Prospective Studies; Quality of Life; Rifamycins; Rifaximin; Thiazoles | 2021 |
Evaluating the efficacy of nitazoxanide in uncomplicated amebic liver abscess.
Topics: Female; Humans; Lactation; Liver Abscess, Amebic; Metronidazole; Nitro Compounds; Pregnancy; Thiazoles | 2021 |
Effect of scheduled antimicrobial and nicotinamide treatment on linear growth in children in rural Tanzania: A factorial randomized, double-blind, placebo-controlled trial.
Topics: Adult; Anti-Infective Agents; Azithromycin; Child Development; Double-Blind Method; Drug Administration Schedule; Female; Growth Disorders; Humans; Infant; Infant, Newborn; Intestinal Diseases, Parasitic; Niacinamide; Nitro Compounds; Pregnancy; Tanzania; Thiazoles | 2021 |
An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2.
Topics: Adult; Antiviral Agents; COVID-19 Drug Treatment; Drug Repositioning; Female; Healthy Volunteers; Humans; Male; Middle Aged; Nitro Compounds; Thiazoles; Young Adult | 2022 |
Cognitive Outcomes at 18 Months: Findings from the Early Life Interventions for Childhood Growth and Development in Tanzania (ELICIT) Trial.
Topics: Anti-Infective Agents; Antiparasitic Agents; Azithromycin; Child Development; Cognitive Aging; Cohort Studies; Early Intervention, Educational; Female; Humans; Infant; Male; Niacinamide; Nitro Compounds; Seasons; Tanzania; Thiazoles; Vitamin B Complex | 2021 |
Nitazoxanide-based therapeutic regimen as a novel treatment for Helicobacter pylori infection in children and adolescents: a randomized trial.
Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Child; Clarithromycin; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Metronidazole; Nitro Compounds; Proton Pump Inhibitors; Thiazoles; Treatment Outcome | 2022 |
Sofosbuvir/ledipasvir in combination or nitazoxanide alone are safe and efficient treatments for COVID-19 infection: A randomized controlled trial for repurposing antivirals.
Topics: Antiviral Agents; Benzimidazoles; COVID-19 Drug Treatment; Drug Repositioning; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Humans; Nitro Compounds; SARS-CoV-2; Sofosbuvir; Thiazoles; Treatment Outcome; Viral Load | 2022 |
Favipiravir and/or nitazoxanide: a randomized, double-blind, 2×2 design, placebo-controlled trial of early therapy in COVID-19 in health workers, their household members, and patients treated at IMSS (FANTAZE).
Topics: Amides; Antiviral Agents; COVID-19 Drug Treatment; Humans; Nitro Compounds; Pyrazines; SARS-CoV-2; Secondary Prevention; Thiazoles; Treatment Outcome | 2022 |
Randomized clinical trial of nitazoxanide or sofosbuvir/daclatasvir for the prevention of SARS-CoV-2 infection.
Topics: Antiviral Agents; Carbamates; COVID-19; Humans; Imidazoles; Nitro Compounds; Pyrrolidines; SARS-CoV-2; Sofosbuvir; South Africa; Thiazoles; Treatment Outcome; Valine | 2022 |
Safety and efficacy of four drug regimens versus standard-of-care for the treatment of symptomatic outpatients with COVID-19: A randomised, open-label, multi-arm, phase 2 clinical trial.
Topics: Adult; COVID-19; Humans; Outpatients; SARS-CoV-2; Thiazoles; Treatment Outcome | 2022 |
321 other study(ies) available for nitazoxanide and thiazoles
| Article | Year |
|---|---|
Pre-clinical toxicology of nitazoxanide--a new antiparasitic compound.
Topics: Animals; Anticestodal Agents; Blood Chemical Analysis; Body Weight; Cats; Dogs; Eye; Female; Irritants; Lethal Dose 50; Male; Mice; Mutagenicity Tests; Nitro Compounds; Organ Size; Rats; Rats, Inbred Strains; Salmonella typhimurium; Species Specificity; Stomach Ulcer; Thiazoles | 1985 |
Nitazoxanide in the treatment of Taenia saginata and Hymenolepis nana infections.
Topics: Adolescent; Adult; Aged; Anticestodal Agents; Child; Drug Evaluation; Female; Humans; Hymenolepiasis; Male; Middle Aged; Nitro Compounds; Taeniasis; Thiazoles | 1984 |
In vitro evaluation of activities of nitazoxanide and tizoxanide against anaerobes and aerobic organisms.
Topics: Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Humans; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles | 1996 |
Efficacy of nitazoxanide against Cryptosporidium parvum in cell culture and in animal models.
Topics: Animals; Antiprotozoal Agents; Cells, Cultured; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; Male; Mice; Mice, SCID; Nitro Compounds; Rabbits; Swine; Thiazoles | 1998 |
Nitazoxanide, a potential drug for eradication of Helicobacter pylori with no cross-resistance to metronidazole.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Helicobacter Infections; Helicobacter pylori; Humans; Metronidazole; Nitro Compounds; Pilot Projects; Thiazoles | 1998 |
Comparative efficacy evaluation of dicationic carbazole compounds, nitazoxanide, and paromomycin against Cryptosporidium parvum infections in a neonatal mouse model.
Topics: Animals; Animals, Newborn; Antiprotozoal Agents; Cryptosporidiosis; Dose-Response Relationship, Drug; Mice; Mice, Inbred ICR; Nitro Compounds; Paromomycin; Thiazoles | 1998 |
Successful treatment with nitazoxanide of Enterocytozoon bieneusi microsporidiosis in a patient with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Animals; Antiprotozoal Agents; Diarrhea; Humans; Male; Microsporida; Microsporidiosis; Nitro Compounds; Thiazoles | 2000 |
Efficacy of treatment with paromomycin, azithromycin, and nitazoxanide in a patient with disseminated cryptosporidiosis.
Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Antiprotozoal Agents; Azithromycin; Cryptosporidiosis; Cryptosporidium; Drug Therapy, Combination; Feces; Female; Humans; Nitro Compounds; Paromomycin; Thiazoles; Treatment Outcome | 1999 |
Activity of nitazoxanide alone and in combination with azithromycin and rifabutin against Cryptosporidium parvum in cell culture.
Topics: AIDS-Related Opportunistic Infections; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cell Survival; Cells, Cultured; Cryptosporidiosis; Cryptosporidium parvum; Humans; Nitro Compounds; Rifabutin; Thiazoles | 2000 |
Efficacy of nitazoxanide, tizoxanide and tizoxanide glucuronide against Cryptosporidium parvum development in sporozoite-infected HCT-8 enterocytic cells.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cryptosporidium parvum; Enterocytes; Glucuronides; Humans; Nitro Compounds; Thiazoles | 2000 |
Blastocystis hominis: neutral red supravital staining and its application to in vitro drug sensitivity testing.
Topics: Amebicides; Animals; Blastocystis hominis; Chloroquine; Coloring Agents; Humans; Metronidazole; Neutral Red; Nitro Compounds; Parasitic Sensitivity Tests; Paromomycin; Quinacrine; Staining and Labeling; Sulfamethoxazole; Tetracycline; Thiazoles; Trimethoprim | 2000 |
In vitro and in vivo activities of nitazoxanide against Clostridium difficile.
Topics: Animals; Anti-Bacterial Agents; Clindamycin; Clostridioides difficile; Cricetinae; Disease Models, Animal; Enterocolitis, Pseudomembranous; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles; Vancomycin | 2000 |
Successful treatment of metronidazole- and albendazole-resistant giardiasis with nitazoxanide in a patient with acquired immunodeficiency syndrome.
Topics: Adult; AIDS-Related Opportunistic Infections; Albendazole; Animals; Antiprotozoal Agents; Drug Resistance, Microbial; Giardia lamblia; Giardiasis; Humans; Male; Metronidazole; Nitro Compounds; Thiazoles; Treatment Outcome | 2001 |
Cryptosporidium clinical trial started.
Topics: AIDS-Related Opportunistic Infections; Anticestodal Agents; Clinical Trials, Phase II as Topic; Cryptosporidiosis; Humans; Nitro Compounds; Thiazoles | 1995 |
Orphan drug designation for NTZ expanded.
Topics: AIDS-Related Opportunistic Infections; Antioxidants; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cryptosporidiosis; Drug Approval; Humans; Immunocompromised Host; Nitro Compounds; Thiazoles; United States; United States Food and Drug Administration | 1997 |
NDA filed for nitazoxanide.
Topics: Anti-Infective Agents; Drug Approval; Humans; Nitro Compounds; Thiazoles; United States; United States Food and Drug Administration | 1998 |
NTZ trials for cryptosporidiosis.
Topics: Adult; AIDS-Related Opportunistic Infections; Anticestodal Agents; Child; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cryptosporidiosis; Diarrhea; Humans; Nitro Compounds; Thiazoles | 1995 |
New treatment for cryptosporidiosis.
Topics: Abdominal Pain; Anticestodal Agents; Cryptosporidiosis; Diarrhea; Humans; Nitro Compounds; Thiazoles | 1995 |
Speaking of the runs.
Topics: AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Cryptosporidiosis; Humans; Microsporida; Microsporidiosis; Nitro Compounds; Thiazoles | 1996 |
Expanded access and expanded trials.
Topics: Anticestodal Agents; Cryptosporidiosis; Drug Approval; HIV Infections; Humans; Nitro Compounds; Thiazoles | 1996 |
New products? What new products?
Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Cantharidin; Humans; Nitro Compounds; Plants, Medicinal; Thiazoles; Thymopentin | 1996 |
Cryptosporidiosis: NTZ available at buyers' club; customs holds 2nd shipment.
Topics: AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Cryptosporidiosis; Humans; Nitro Compounds; Thiazoles | 1996 |
Incoming NTZ blocked by US customs. People With AIDS Health Group.
Topics: AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Cryptosporidiosis; Drug and Narcotic Control; Humans; Nitro Compounds; Thiazoles; United States | 1996 |
NTZ--we got it.
Topics: AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Cryptosporidiosis; Diarrhea; Humans; Mexico; Nitro Compounds; Thiazoles | 1996 |
NTZ for cryptosporidiosis: larger expanded access; buyers' club/FDA conflict. Food and Drug Administration.
Topics: Altruism; Clinical Trials as Topic; Consumer Organizations; Cryptosporidiosis; Drug Industry; Drugs, Investigational; Health Services Accessibility; Humans; Nitro Compounds; Thiazoles; Triazoles; United States; United States Food and Drug Administration | 1996 |
NTZ submitted to FDA for cryptosporidiosis. Food and Drug Administration.
Topics: AIDS-Related Opportunistic Infections; Antioxidants; Cryptosporidiosis; Drug Approval; Humans; Nitro Compounds; Thiazoles; United States; United States Food and Drug Administration | 1998 |
Cryptosporidiosis gets a new treatment.
Topics: AIDS-Related Opportunistic Infections; Antiparasitic Agents; Cryptosporidiosis; Diarrhea; Humans; Nitro Compounds; Thiazoles | 1998 |
Nitazoxanide for cryptosporidial diarrhea.
Topics: AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Clinical Trials as Topic; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; Drug Therapy, Combination; Health Services Accessibility; Humans; Nitro Compounds; Risk Factors; Thiazoles | 1998 |
NTZ: advisory committee votes against approval.
Topics: Acquired Immunodeficiency Syndrome; Antiprotozoal Agents; Clinical Trials as Topic; Cryptosporidiosis; Diarrhea; Drug Approval; Health Services Accessibility; Humans; Nitro Compounds; Thiazoles; United States; United States Food and Drug Administration | 1998 |
Case report: Nitazoxanide treatment failure in chronic isosporiasis.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Antiprotozoal Agents; Bile; Chronic Disease; Humans; Immunocompetence; Injections, Intravenous; Isospora; Isosporiasis; Male; Middle Aged; Nitro Compounds; Thiazoles; Treatment Failure; Trimethoprim, Sulfamethoxazole Drug Combination | 2001 |
Experimental infection of cats with Tritrichomonas foetus.
Topics: Animals; Antigens, Protozoan; Antiprotozoal Agents; Cat Diseases; Cats; Cryptosporidiosis; Cryptosporidium; Diarrhea; Feces; Female; Intestinal Diseases; Intestinal Mucosa; Nitro Compounds; Parasite Egg Count; Prednisolone; Protozoan Infections; Protozoan Infections, Animal; Specific Pathogen-Free Organisms; Thiazoles; Tritrichomonas foetus | 2001 |
In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis.
Topics: Amebicides; Animals; Antiprotozoal Agents; Antitrichomonal Agents; Drug Resistance, Microbial; Entamoeba histolytica; Giardia lamblia; Humans; Microbial Sensitivity Tests; Nitro Compounds; Structure-Activity Relationship; Thiazoles; Trichomonas vaginalis | 2002 |
Treatment of intestinal parasitic infections: a review of nitazoxanide.
Topics: Anthelmintics; Antiprotozoal Agents; Helminthiasis; Humans; Intestinal Diseases, Parasitic; Nitro Compounds; Protozoan Infections; Thiazoles | 2002 |
Nitazoxanide as a broad-spectrum antiparasitic agent.
Topics: Animals; Anti-Bacterial Agents; Clostridioides difficile; Cricetinae; Enterocolitis, Pseudomembranous; Humans; Middle Aged; Nitro Compounds; Parasites; Parasitic Diseases; Thiazoles | 2002 |
Enzymes associated with reductive activation and action of nitazoxanide, nitrofurans, and metronidazole in Helicobacter pylori.
Topics: Biotransformation; Cloning, Molecular; DNA Damage; Drug Resistance, Bacterial; Escherichia coli; Helicobacter pylori; Ketone Oxidoreductases; Metronidazole; Mutation; Nitro Compounds; Nitrofurans; Nitroreductases; Oxidation-Reduction; Pyruvate Synthase; Substrate Specificity; Thiazoles | 2002 |
In-vitro transfer of nitazoxanide across the intestinal epithelial barrier.
Topics: Anti-Bacterial Agents; Cell Line; Colon; Diffusion Chambers, Culture; Electrophysiology; Humans; Intestinal Absorption; Intestinal Mucosa; Nitro Compounds; Thiazoles; Tight Junctions; Tumor Cells, Cultured | 2002 |
In vitro parasiticidal effect of Nitazoxanide against Echinococcus multilocularis metacestodes.
Topics: Alkaline Phosphatase; Animals; Anticestodal Agents; Cells, Cultured; Echinococcosis; Echinococcus; Female; Gerbillinae; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Microscopy, Electron, Scanning Transmission; Nitro Compounds; Thiazoles | 2003 |
Nitazoxanide (Alinia)--a new anti-protozoal agent.
Topics: Administration, Oral; Adult; Antiprotozoal Agents; Child; Child, Preschool; Diarrhea; Drug Administration Schedule; Giardiasis; Humans; Infant; Intestinal Absorption; Nitro Compounds; Randomized Controlled Trials as Topic; Thiazoles | 2003 |
Long-lasting anticryptosporidial activity of nitazoxanide in an immunosuppressed rat model.
Topics: Adenosine; Animals; Antiprotozoal Agents; Cryptosporidiosis; Cryptosporidium parvum; Disease Models, Animal; Feces; Immunocompromised Host; Male; Nitro Compounds; Parasite Egg Count; Paromomycin; Rats; Rats, Sprague-Dawley; Thiazoles | 2003 |
Nitazoxanide: an important advance in anti-parasitic therapy.
Topics: Antiparasitic Agents; Cryptosporidiosis; Giardiasis; Helminthiasis; Humans; Intestinal Diseases, Parasitic; Nitro Compounds; Thiazoles | 2003 |
Epidemiology and control of intestinal parasites with nitazoxanide in children in Mexico.
Topics: Adolescent; Antiparasitic Agents; Child; Child, Preschool; Feces; Female; Helminthiasis; Humans; Intestinal Diseases, Parasitic; Male; Mexico; Nitro Compounds; Parasite Egg Count; Prevalence; Protozoan Infections; Thiazoles; Treatment Outcome | 2003 |
Human studies provide insight into the pathogenesis, immunology, and treatment of cryptosporidiosis.
Topics: Animals; Antiprotozoal Agents; Cryptosporidiosis; Cryptosporidium; Humans; Immunologic Techniques; Nitro Compounds; Thiazoles | 2003 |
Nematocidal activity of nitazoxanide in laboratory models.
Topics: Animals; Antinematodal Agents; Antiparasitic Agents; Biological Assay; Caenorhabditis elegans; Disease Models, Animal; Dose-Response Relationship, Drug; Heligmosomatoidea; Mice; Nematoda; Nitro Compounds; Parasitic Diseases, Animal; Thiazoles; Trichinella spiralis; Trichinellosis | 2003 |
New drugs 04, part 1.
Topics: Adalimumab; Alefacept; alpha-Galactosidase; Anisoles; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antioxidants; Antiprotozoal Agents; Antirheumatic Agents; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Drug Approval; Drug Therapy; Fabry Disease; Gefitinib; Humans; Iduronidase; Indoles; Isoenzymes; Lentigo; Lung Neoplasms; Migraine Disorders; Mucopolysaccharidosis I; Nitro Compounds; Patient Education as Topic; Propylamines; Psoriasis; Pyrrolidines; Quinazolines; Recombinant Fusion Proteins; Serotonin Receptor Agonists; Thiazoles; Tryptamines | 2004 |
Role of wheat germ agglutinin (WGA) in treatment of experimental cryptosporidiosis.
Topics: Animals; Animals, Suckling; Antiprotozoal Agents; Cryptosporidiosis; Cryptosporidium parvum; Disease Models, Animal; Immunocompromised Host; Mice; Nitro Compounds; Thiazoles; Wheat Germ Agglutinins | 2003 |
Secondary and primary murine alveolar echinococcosis: combined albendazole/nitazoxanide chemotherapy exhibits profound anti-parasitic activity.
Topics: Albendazole; Animals; Antiparasitic Agents; Drug Therapy, Combination; Echinococcosis; Mice; Mice, Inbred BALB C; Microscopy, Electron; Nitro Compounds; Pulmonary Alveoli; Thiazoles; Time Factors; Treatment Outcome | 2004 |
In vitro effects of nitazoxanide on Echinococcus granulosus protoscoleces and metacestodes.
Topics: Albendazole; Animals; Anthelmintics; Anticestodal Agents; Dose-Response Relationship, Drug; Echinococcosis; Echinococcus; Microscopy, Electron; Microscopy, Electron, Scanning; Nitro Compounds; Thiazoles | 2004 |
Present and future control of cryptosporidiosis in humans and animals.
Topics: Animals; Antiparasitic Agents; Cattle; Cattle Diseases; Colostrum; Cryptosporidiosis; Cryptosporidium parvum; Female; Humans; Immunization, Passive; Nitro Compounds; Pregnancy; Protozoan Proteins; Protozoan Vaccines; Thiazoles; Vaccines, Attenuated; Water | 2004 |
Nitazoxanide: a new thiazolide antiparasitic agent.
Topics: Antiparasitic Agents; Humans; Molecular Structure; Nitro Compounds; Parasitic Diseases; Thiazoles | 2005 |
Nitazoxanide for treatment of intestinal parasites in children.
Topics: Adolescent; Adult; Animals; Antiparasitic Agents; Child; Child, Preschool; Cryptosporidium; Diarrhea; Giardia; Humans; Infant; Intestinal Diseases, Parasitic; Nitro Compounds; Protozoan Infections; Thiazoles | 2005 |
In vitro efficacies of nitazoxanide and other thiazolides against Neospora caninum tachyzoites reveal antiparasitic activity independent of the nitro group.
Topics: Animals; Antiprotozoal Agents; Cell Adhesion; Cells, Cultured; Fibroblasts; Humans; Microscopy, Electron, Transmission; Neospora; Nitro Compounds; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Thiazoles; Tissue Culture Techniques | 2005 |
Nitazoxanide.
Topics: Animals; Antiparasitic Agents; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; Giardia lamblia; Giardiasis; Humans; Nitro Compounds; Thiazoles | 2005 |
Efficacy of nitazoxanide and paromomycin in biliary tract cryptosporidiosis in an immunosuppressed gerbil model.
Topics: Amebicides; Animals; Antiprotozoal Agents; Biliary Tract Diseases; Cattle; Cryptosporidiosis; Cryptosporidium parvum; Dexamethasone; Feces; Gallbladder; Gerbillinae; Ileum; Immunosuppression Therapy; Immunosuppressive Agents; Nitro Compounds; Paromomycin; Thiazoles | 2006 |
In vitro effects of thiazolides on Giardia lamblia WB clone C6 cultured axenically and in coculture with Caco2 cells.
Topics: Animals; Caco-2 Cells; Coculture Techniques; Giardia lamblia; Giardiasis; Humans; Metronidazole; Nitro Compounds; Parasitic Sensitivity Tests; Thiazoles; Tissue Culture Techniques | 2006 |
14-3-3- and II/3-10-gene expression as molecular markers to address viability and growth activity of Echinococcus multilocularis metacestodes.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; Antiparasitic Agents; Base Sequence; Echinococcus multilocularis; Electrophoresis, Polyacrylamide Gel; Female; Fluorescent Antibody Technique; Gene Amplification; Gene Expression Regulation; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Nitro Compounds; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thiazoles | 2006 |
Activities of tizoxanide and nitazoxanide compared to those of five other thiazolides and three other agents against anaerobic species.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteria, Anaerobic; Clindamycin; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles | 2006 |
Hymenolepis nana infection: symptoms and response to nitazoxanide in field conditions.
Topics: Animals; Anthelmintics; Case-Control Studies; Humans; Hymenolepiasis; Hymenolepis nana; Intestinal Diseases, Parasitic; Nitro Compounds; Thiazoles; Treatment Outcome | 2007 |
Nitazoxanide for rotavirus diarrhoea?
Topics: Adult; Anti-Infective Agents; Child; Child, Preschool; Diarrhea; Humans; Infant; Nitro Compounds; Rotavirus Infections; Thiazoles | 2006 |
Current status of anti-diarrheal and anti-secretory drugs in the management of acute childhood diarrhea.
Topics: Acute Disease; Antidiarrheals; Antiparasitic Agents; Child; Child, Preschool; Cholera; Diarrhea; Disease Outbreaks; Dysentery, Bacillary; Female; Humans; Infant; Intestinal Diseases, Parasitic; Male; Nitro Compounds; Probiotics; Thiazoles; Thiorphan | 2006 |
In vitro activities of itraconazole, methiazole, and nitazoxanide versus Echinococcus multilocularis larvae.
Topics: Animals; Antiparasitic Agents; Benzimidazoles; Carbamates; Echinococcus multilocularis; Gerbillinae; Itraconazole; Larva; Nitro Compounds; Thiazoles | 2006 |
[Development of novel antihelminthic therapies].
Topics: Anthelmintics; Drug Resistance; Drug Therapy, Combination; Helminthiasis; Humans; Nitro Compounds; Phenylenediamines; Plants, Medicinal; Thiazoles | 2006 |
Efficacy of nitazoxanide, tizoxanide and tizoxanide/albendazole sulphoxide combination against Taenia crassiceps cysts.
Topics: Albendazole; Animals; Anticestodal Agents; Cysticercosis; Drug Combinations; Drug Synergism; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Nitro Compounds; Parasitic Sensitivity Tests; Taenia; Thiazoles | 2007 |
Structure-activity relationships from in vitro efficacies of the thiazolide series against the intracellular apicomplexan protozoan Neospora caninum.
Topics: Animals; Antiprotozoal Agents; Cattle; Dogs; Drug Design; Neospora; Nitro Compounds; Polymerase Chain Reaction; Structure-Activity Relationship; Thiazoles; Thiazolidines; Tissue Culture Techniques | 2007 |
Nitazoxanide versus metronidazole for Clostridium difficile-associated colitis.
Topics: Aged; Animals; Anti-Bacterial Agents; Clostridioides difficile; Cricetinae; Enterocolitis, Pseudomembranous; Female; Humans; Male; Metronidazole; Nitro Compounds; Thiazoles; Treatment Outcome | 2007 |
Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni.
Topics: Acetyl Coenzyme A; Animals; Antiprotozoal Agents; Bacteria, Anaerobic; Campylobacter jejuni; Carbon Dioxide; Cloning, Molecular; Clostridium; Culture Media; Enzyme Inhibitors; Helicobacter pylori; Kinetics; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Nitro Compounds; Parasites; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction; Thiamine Pyrophosphate; Thiazoles | 2007 |
Efficacy of nitazoxanide for cyclosporiasis in patients with sulfa allergy.
Topics: Adult; Animals; Antiparasitic Agents; Cyclospora; Cyclosporiasis; Drug Hypersensitivity; Female; Humans; Nitro Compounds; Sulfonamides; Thiazoles | 2007 |
Nitazoxanide or CD3+/CD4+ lymphocytes for recovery from severe Cryptosporidium infection after allogeneic bone marrow transplant?
Topics: Animals; Antigens, CD; Antiparasitic Agents; Biopsy; CD3 Complex; CD4-Positive T-Lymphocytes; Child; Colon; Cryptosporidiosis; Cryptosporidium; Humans; Leukemia, Myeloid, Acute; Lymphocyte Transfusion; Male; Nitro Compounds; Stem Cell Transplantation; Thiazoles; Transplantation, Homologous | 2007 |
In vitro efficacy of nitro- and bromo-thiazolyl-salicylamide compounds (thiazolides) against Besnoitia besnoiti infection in Vero cells.
Topics: Animals; Antiprotozoal Agents; Cell Adhesion; Chlorocebus aethiops; Host-Parasite Interactions; Microscopy, Electron, Transmission; Nitro Compounds; Parasitic Sensitivity Tests; Sarcocystidae; Thiazoles; Time Factors; Vero Cells | 2007 |
Isolated gastric cryptosporidiosis in an immunocompetent patient.
Topics: Aged, 80 and over; Animals; Antiparasitic Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Chronic Disease; Cryptosporidiosis; Cryptosporidium parvum; Humans; Immunocompetence; Male; Nitro Compounds; Prednisolone; Stomach; Thiazoles; Treatment Outcome | 2007 |
A novel Giardia lamblia nitroreductase, GlNR1, interacts with nitazoxanide and other thiazolides.
Topics: Amino Acid Sequence; Animals; Antiparasitic Agents; Chromatography, Affinity; Enzyme Inhibitors; Giardia lamblia; Molecular Sequence Data; Nitro Compounds; Nitroreductases; Parasitic Sensitivity Tests; Protozoan Proteins; Thiazoles | 2007 |
Failure of nitazoxanide to cure trichomoniasis in three women.
Topics: Adult; Antiparasitic Agents; Drug Resistance, Microbial; Female; Humans; Middle Aged; Nitro Compounds; Retrospective Studies; Thiazoles; Treatment Failure; Trichomonas Infections | 2007 |
Characterization of Giardia lamblia WB C6 clones resistant to nitazoxanide and to metronidazole.
Topics: Animals; Antiprotozoal Agents; Clone Cells; DNA Primers; Drug Resistance; Gene Expression Regulation; Giardia lamblia; Metronidazole; Nitro Compounds; Protein Disulfide-Isomerases; Pyruvate Oxidase; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Thiazoles | 2007 |
Nitazoxanide in the treatment of Ascaris lumbricoides in a rural zone of Colima, Mexico.
Topics: Adolescent; Adult; Animals; Antiparasitic Agents; Ascariasis; Ascaris lumbricoides; Child; Humans; Intestinal Diseases, Parasitic; Mexico; Nitro Compounds; Prevalence; Thiazoles | 2007 |
Neospora caninum: functional inhibition of protein disulfide isomerase by the broad-spectrum anti-parasitic drug nitazoxanide and other thiazolides.
Topics: Animals; Antiparasitic Agents; Chlorocebus aethiops; Chromatography, Affinity; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Female; Immunoblotting; Neospora; Nitro Compounds; Protein Disulfide-Isomerases; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Vero Cells | 2008 |
Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication.
Topics: Antiviral Agents; Cell Line; Drug Resistance, Viral; Hepacivirus; Hepatitis Antigens; Hepatitis B virus; Humans; Mutation; Nitro Compounds; Serum; Thiazoles; Virus Replication | 2008 |
Anaerobic NADH-fumarate reductase system is predominant in the respiratory chain of Echinococcus multilocularis, providing a novel target for the chemotherapy of alveolar echinococcosis.
Topics: Anaerobiosis; Animals; Echinococcosis, Hepatic; Echinococcus multilocularis; Electron Transport; Enzyme Inhibitors; Mitochondria; Nitro Compounds; Oxidoreductases Acting on CH-CH Group Donors; Quinazolines; Rotenone; Thiazoles; Ubiquinone | 2008 |
Nitazoxanide: clinical studies of a broad-spectrum anti-infective agent.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiparasitic Agents; Humans; Nitro Compounds; Parasitic Diseases; Thiazoles | 2007 |
Preliminary evidence of nitazoxanide activity on Toxocara canis in a mouse model.
Topics: Animals; Disease Models, Animal; Mice; Nitro Compounds; Thiazoles; Toxocara canis; Toxocariasis | 2008 |
Modelling geographic variation in the cost-effectiveness of control policies for infectious vector diseases: the example of Chagas disease.
Topics: Chagas Disease; Communicable Diseases; Cost-Benefit Analysis; Geography; Health Policy; Infection Control; Models, Econometric; Nitro Compounds; Thiazoles | 2008 |
Immunochemotherapy for cryptosporidiosis in immunosuppressed mouse model.
Topics: Animals; Antiprotozoal Agents; Cryptosporidiosis; Disease Models, Animal; Drug Therapy, Combination; Humans; Immunocompromised Host; Immunotherapy; Interferon-gamma; Life Cycle Stages; Mice; Nitro Compounds; Oocysts; Parasite Egg Count; Paromomycin; Random Allocation; Thiazoles; Time Factors; Treatment Outcome | 2007 |
Identification of differentially expressed genes in a Giardia lamblia WB C6 clone resistant to nitazoxanide and metronidazole.
Topics: Animals; Antigens, Protozoan; Antigens, Surface; Antiprotozoal Agents; Drug Resistance; Gene Expression Profiling; Giardia lamblia; Heat-Shock Proteins; Metronidazole; Mutation; Nitro Compounds; Nitroreductases; Oligonucleotide Array Sequence Analysis; Protein Disulfide-Isomerases; Protozoan Proteins; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles | 2008 |
[New antiparasitic drugs].
Topics: Albendazole; Antimalarials; Antiparasitic Agents; Benzimidazoles; Cyclohexanes; Fatty Acids, Unsaturated; Humans; Ivermectin; Nitro Compounds; Phosphorylcholine; Praziquantel; Sesquiterpenes; Thiazoles; Triclabendazole | 2008 |
In vitro and in vivo treatments of echinococcus protoscoleces and metacestodes with artemisinin and artemisinin derivatives.
Topics: Albendazole; Animals; Anti-Infective Agents; Antiparasitic Agents; Artemisinins; Drug Therapy, Combination; Echinococcosis; Echinococcus granulosus; Echinococcus multilocularis; Humans; Larva; Mice; Mice, Inbred BALB C; Nitro Compounds; Parasitic Sensitivity Tests; Thiazoles; Treatment Outcome | 2008 |
Nitazoxanide for cryptosporidial infection in Crohn's disease.
Topics: Adult; Animals; Antiprotozoal Agents; Colitis; Crohn Disease; Cryptosporidiosis; Cryptosporidium parvum; Female; Humans; Intestinal Diseases, Parasitic; Nitro Compounds; Opportunistic Infections; Thiazoles | 2008 |
Potential for hepatitis C virus resistance to nitazoxanide or tizoxanide.
Topics: Antiviral Agents; Cell Line; Cytidine; Drug Resistance, Viral; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Nitro Compounds; Recombinant Proteins; Replicon; Ribavirin; Thiazoles; Virus Replication | 2008 |
Rapid determination of nitazoxanide in tablets using reversed-phase ultra-performance liquid chromatography (UPLC) and high-performance liquid chromatography.
Topics: Algorithms; Antiprotozoal Agents; Calibration; Chromatography, High Pressure Liquid; Nitro Compounds; Pharmaceutical Solutions; Reference Standards; Reproducibility of Results; Tablets; Thiazoles | 2008 |
Nitazoxanide treatment of Cryptosporidium parvum in human immunodeficiency virus-infected children.
Topics: AIDS-Related Opportunistic Infections; Animals; Child, Preschool; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; HIV Infections; Humans; Infant; Nitro Compounds; Thiazoles | 2008 |
Liquid chromatography-tandem mass spectrometry analysis of nitazoxanide and its major metabolites in goat.
Topics: Administration, Oral; Animals; Antiparasitic Agents; Chromatography, High Pressure Liquid; Goats; Male; Nitro Compounds; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Thiazoles | 2008 |
Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora.
Topics: Ampicillin; Bacteria, Anaerobic; Feces; Microbial Sensitivity Tests; Neomycin; Nitro Compounds; Rifamycins; Rifaximin; Sulbactam; Teicoplanin; Thiazoles; Vancomycin | 2009 |
Brugia malayi: Effects of nitazoxanide and tizoxanide on adult worms and microfilariae of filarial nematodes.
Topics: Animals; Antiparasitic Agents; Brugia malayi; Dose-Response Relationship, Drug; Female; Filariasis; Gerbillinae; Male; Microfilariae; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nitro Compounds; Thiazoles | 2009 |
Nitazoxanide: beyond parasites toward a novel agent for hepatitis C.
Topics: Antiparasitic Agents; Antiviral Agents; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Nitro Compounds; Thiazoles | 2009 |
Case report: nitazoxanide for treatment of refractory bony hydatid disease.
Topics: Aged; Animals; Antiparasitic Agents; Bone Diseases, Infectious; Echinococcosis; Echinococcus granulosus; Fatal Outcome; Female; Humans; Magnetic Resonance Imaging; Nitro Compounds; Pelvis; Radiography; Thiazoles; Treatment Outcome | 2009 |
Limitations of amphotericin B and nitazoxanide in the treatment of alveolar echinococcosis.
Topics: Amphotericin B; Anthelmintics; Disease Progression; Drug Therapy, Combination; Echinococcosis, Hepatic; Follow-Up Studies; Humans; Male; Middle Aged; Nitro Compounds; Thiazoles; Treatment Failure | 2009 |
Nitazoxanide, tizoxanide and a new analogue [4-nitro-N-(5-nitro-1,3-thiazol-2-yl)benzamide; NTB] inhibit the growth of kinetoplastid parasites (Trypanosoma cruzi and Leishmania mexicana) in vitro.
Topics: Animals; Antiprotozoal Agents; Benzamides; Humans; Inhibitory Concentration 50; Leishmania mexicana; Molecular Structure; Nitro Compounds; Thiazoles; Trypanosoma cruzi | 2009 |
Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides.
Topics: Antiparasitic Agents; Antiviral Agents; Clinical Trials as Topic; Double-Blind Method; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Nitro Compounds; Placebos; Thiazoles | 2009 |
Nitazoxanide and probiotics for the treatment of recurrent Clostridium difficile infection in a peritoneal dialysis patient.
Topics: Antiparasitic Agents; Clostridioides difficile; Clostridium Infections; Female; Gastrointestinal Diseases; Humans; Kidney Failure, Chronic; Middle Aged; Nitro Compounds; Peritoneal Dialysis; Probiotics; Thiazoles | 2009 |
Cryptosporidium and Giardia: treatment options and prospects for new drugs.
Topics: AIDS-Related Opportunistic Infections; Antibodies, Monoclonal; Antiparasitic Agents; Antiretroviral Therapy, Highly Active; Azithromycin; Benzimidazoles; Cryptosporidiosis; Giardia lamblia; Giardiasis; Humans; Nitro Compounds; Nitroimidazoles; Paromomycin; Roxithromycin; Thiazoles | 2010 |
Thiazolides, a new class of anti-influenza molecules targeting viral hemagglutinin at the post-translational level.
Topics: Animals; Antiparasitic Agents; Antiviral Agents; Cell Membrane; Dogs; HeLa Cells; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Jurkat Cells; Nitro Compounds; Protein Processing, Post-Translational; Protein Transport; Thiazoles; Virus Assembly | 2009 |
The anti-hepatitis C agent nitazoxanide induces phosphorylation of eukaryotic initiation factor 2alpha via protein kinase activated by double-stranded RNA activation.
Topics: Antiparasitic Agents; Antiviral Agents; Cell Culture Techniques; Cell Line; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Hepatitis C; Hepatocytes; Humans; Interferons; Nitro Compounds; Phosphorylation; Thiazoles | 2009 |
Sensitive high performance liquid chromatographic assay for nitazoxanide metabolite in plasma.
Topics: Animals; Anthelmintics; Biological Availability; Calibration; Chromatography, High Pressure Liquid; Half-Life; Male; Nitro Compounds; Quality Control; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Thiazoles | 2009 |
Bone hydatid disease refractory to nitazoxanide treatment.
Topics: Adult; Albendazole; Anthelmintics; Bone Diseases; Cimetidine; Drug Resistance; Echinococcosis; Histamine H2 Antagonists; Humans; Lumbar Vertebrae; Male; Nitro Compounds; Thiazoles | 2009 |
Cryptosporidiosis in paediatric renal transplantation.
Topics: Adolescent; Antiparasitic Agents; Biopsy; Child; Cohort Studies; Cryptosporidiosis; Diarrhea; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Mycophenolic Acid; Nitro Compounds; Prednisone; Sirolimus; Tacrolimus; Thiazoles; Time Factors; Transplantation, Homologous; Treatment Outcome | 2009 |
Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance.
Topics: Antiparasitic Agents; Antitubercular Agents; Dose-Response Relationship, Drug; Drug Resistance; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitro Compounds; Thiazoles | 2009 |
Stable expression of Escherichia coli beta-glucuronidase A (GusA) in Giardia lamblia: application to high-throughput drug susceptibility testing.
Topics: Animals; Antiprotozoal Agents; Drug Evaluation, Preclinical; Escherichia coli; Escherichia coli Proteins; Genes, Reporter; Giardia lamblia; Glucuronidase; Metronidazole; Microbial Sensitivity Tests; Microbial Viability; Nitro Compounds; Pharmaceutical Preparations; Recombinant Proteins; Thiazoles | 2009 |
LC: analysis of photodegradation kinetics of nitazoxanide in pharmaceutical formulations.
Topics: Antiparasitic Agents; Chemistry, Pharmaceutical; Chromatography, Liquid; Drug Stability; Kinetics; Nitro Compounds; Photolysis; Powders; Tablets; Thiazoles; Ultraviolet Rays | 2009 |
Evaluation of new thiazolide/thiadiazolide derivatives reveals nitro group-independent efficacy against in vitro development of Cryptosporidium parvum.
Topics: Antiprotozoal Agents; Cryptosporidium parvum; Humans; Inhibitory Concentration 50; Nitro Compounds; Parasitic Sensitivity Tests; Structure-Activity Relationship; Thiadiazines; Thiazoles | 2010 |
Treatment of chronic hepatitis C using a 4-week lead-in with nitazoxanide before peginterferon plus nitazoxanide.
Topics: Adult; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Nitro Compounds; Pilot Projects; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Thiazoles; Time Factors; Treatment Outcome; Young Adult | 2010 |
Nitazoxanide inhibits biofilm production and hemagglutination by enteroaggregative Escherichia coli strains by blocking assembly of AafA fimbriae.
Topics: Adhesins, Escherichia coli; Anti-Infective Agents; Base Sequence; Biofilms; Child; Diarrhea; DNA Primers; DNA, Bacterial; Escherichia coli; Escherichia coli Infections; Fimbriae, Bacterial; Genes, Bacterial; Hemagglutination; Humans; Mutation; Nitro Compounds; Thiazoles; Virulence | 2010 |
Biliary fascioliasis mimicking sphincter of Oddi dysfunction.
Topics: Adult; Animals; Antiparasitic Agents; Cholangiopancreatography, Endoscopic Retrograde; Diagnosis, Differential; Emigrants and Immigrants; Ethiopia; Fasciola hepatica; Fascioliasis; Female; Humans; Nitro Compounds; Sphincter of Oddi Dysfunction; Thiazoles | 2010 |
Nitazoxanide inhibits biofilm formation by Staphylococcus epidermidis by blocking accumulation on surfaces.
Topics: Anti-Bacterial Agents; Biofilms; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Nitro Compounds; Staphylococcus epidermidis; Thiazoles; Vancomycin; Zinc | 2010 |
Eosinophilia secondary to strongyloides in Rhode Island.
Topics: Adult; Albendazole; Animals; Anthelmintics; Antiparasitic Agents; Blastocystis hominis; Blastocystis Infections; Eosinophilia; Humans; Immunoglobulin G; Male; Nitro Compounds; Rhode Island; Strongyloides stercoralis; Strongyloidiasis; Thiazoles | 2010 |
The pharmacokinetics of nitazoxanide active metabolite (tizoxanide) in goats and its protein binding ability in vitro.
Topics: Animals; Antiparasitic Agents; Blood Proteins; Goats; Male; Nitro Compounds; Protein Binding; Thiazoles | 2010 |
Biological activity of modified and exchanged 2-amino-5-nitrothiazole amide analogues of nitazoxanide.
Topics: Anti-Bacterial Agents; Antiparasitic Agents; Campylobacter jejuni; Clostridioides difficile; Helicobacter pylori; Nitro Compounds; Pyruvate Synthase; Small Molecule Libraries; Thiazoles | 2010 |
In vitro and in vivo antileishmanial efficacy of nitazoxanide against Leishmania donovani.
Topics: Animals; Antiprotozoal Agents; Female; Leishmania donovani; Leishmaniasis, Visceral; Liver; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Nitro Compounds; Spleen; Thiazoles; Treatment Outcome | 2010 |
Susceptibility in vitro of clinically metronidazole-resistant Trichomonas vaginalis to nitazoxanide, toyocamycin, and 2-fluoro-2'-deoxyadenosine.
Topics: Anaerobiosis; Antitrichomonal Agents; Deoxyadenosines; Drug Resistance; Female; Humans; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles; Toyocamycin; Trichomonas vaginalis; Trichomonas Vaginitis | 2010 |
Short course combination therapy for giardiasis after nitroimidazole failure.
Topics: Animals; Antiparasitic Agents; Drug Therapy, Combination; Giardiasis; Humans; Nitro Compounds; Nitroimidazoles; Thiazoles; Treatment Failure; Treatment Outcome | 2010 |
Diagnosis and treatment of digestive cryptosporidiosis in allogeneic haematopoietic stem cell transplant recipients: a prospective single centre study.
Topics: Adult; Animals; Azithromycin; Cryptosporidiosis; Cryptosporidium parvum; Diagnosis, Differential; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Lymphopenia; Male; Middle Aged; Nitro Compounds; Thiazoles; Transplantation, Homologous; Young Adult | 2011 |
Nitazoxanide use in rota viral diarrhea. Cure or controversy?
Topics: Antiparasitic Agents; Child; Child, Preschool; Diarrhea; Humans; Infant; Nitro Compounds; Rotavirus Infections; Thiazoles | 2010 |
Nitazoxanide in the treatment of chronic cutaneous leishmaniasis resistant to traditional sodium stibogluconate.
Topics: Administration, Oral; Antimony Sodium Gluconate; Antiparasitic Agents; Biopsy, Needle; Drug Administration Schedule; Drug Resistance; Follow-Up Studies; Humans; Immunohistochemistry; Infusions, Intravenous; Leishmaniasis, Cutaneous; Male; Nitro Compounds; Retreatment; Severity of Illness Index; Thiazoles; Treatment Outcome; Young Adult | 2011 |
Synthesis and antimicrobial evaluation of nitazoxanide-based analogues: identification of selective and broad spectrum activity.
Topics: Anti-Bacterial Agents; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles | 2011 |
Nitazoxanide is active against Clostridium difficile strains with reduced susceptibility to metronidazole.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Drug Resistance, Bacterial; Humans; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles | 2011 |
Nitroreductase (GlNR1) increases susceptibility of Giardia lamblia and Escherichia coli to nitro drugs.
Topics: Anti-Infective Agents; Escherichia coli; Giardia lamblia; Humans; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Nitroreductases; Oxidation-Reduction; Parasitic Sensitivity Tests; Thiazoles | 2011 |
Synthesis of benzologues of Nitazoxanide and Tizoxanide: a comparative study of their in vitro broad-spectrum antiprotozoal activity.
Topics: Antiprotozoal Agents; Giardia; Molecular Structure; Nitro Compounds; Plasmodium; Thiazoles; Trichomonas vaginalis | 2011 |
Efficacy of ginkgolic acids against Cryptosporidium andersoni in cell culture.
Topics: Allyl Compounds; Antiprotozoal Agents; Artemether; Artemisinins; Cell Line; Cell Survival; Cryptosporidium; Disulfides; Humans; Nitro Compounds; Parasitic Sensitivity Tests; Salicylates; Thiazoles | 2011 |
Potential drug development candidates for human soil-transmitted helminthiases.
Topics: Aminoacetonitrile; Animals; Anthelmintics; Depsipeptides; Drug Approval; Drug Evaluation, Preclinical; Europe; Helminthiasis; Helminthiasis, Animal; Humans; Nitro Compounds; Thiazoles; United States | 2011 |
Mutations in HCV non-structural genes do not contribute to resistance to nitazoxanide in replicon-containing cells.
Topics: Antiviral Agents; Base Sequence; Cell Line; Cloning, Molecular; Drug Resistance, Viral; Escherichia coli; Genotype; Hepacivirus; Hepatitis C; Host-Pathogen Interactions; Humans; Interferons; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nitro Compounds; Phenotype; Plasmids; Replicon; RNA, Viral; Thiazoles; Transformation, Bacterial; Viral Nonstructural Proteins; Virus Replication | 2011 |
Cryptosporidium-malnutrition interactions: mucosal disruption, cytokines, and TLR signaling in a weaned murine model.
Topics: Animals; Antiparasitic Agents; Cryptosporidiosis; Cryptosporidium parvum; Cytokines; Disease Models, Animal; DNA, Protozoan; Feces; Female; Ileum; Intestinal Mucosa; Malnutrition; Mice; Mice, Inbred C57BL; Nitro Compounds; RNA, Messenger; Thiazoles; Toll-Like Receptors; Weaning; Weight Gain | 2011 |
Comparative drug susceptibility study of five clonal strains of Trichomonas vaginalis in vitro.
Topics: Antiprotozoal Agents; Azoles; Humans; Nitro Compounds; Parasitic Sensitivity Tests; Thiazoles; Trichomonas vaginalis | 2011 |
Experimental treatment of Neospora caninum-infected mice with the arylimidamide DB750 and the thiazolide nitazoxanide.
Topics: Administration, Oral; Amidines; Animals; Body Weight; Brain; Cell Line; Chlorocebus aethiops; Coccidiosis; Coccidiostats; Disease Models, Animal; DNA, Protozoan; Female; Fibroblasts; Humans; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Neospora; Nitro Compounds; Polymerase Chain Reaction; Pyridines; Random Allocation; Thiazoles; Vero Cells | 2011 |
Impaired parasite attachment as fitness cost of metronidazole resistance in Giardia lamblia.
Topics: Animals; Antiprotozoal Agents; Cell Line; Drug Resistance; Furazolidone; Giardia lamblia; Giardiasis; Glucose; Metronidazole; Mice; Mice, Inbred C57BL; Nitro Compounds; Thiazoles; Tinidazole | 2011 |
Norovirus gastroenteritis successfully treated with nitazoxanide.
Topics: Adult; Anti-Infective Agents; Caliciviridae Infections; Diagnosis, Differential; Feces; Gastroenteritis; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Leukemia, Myeloid, Acute; Male; Nitro Compounds; Norovirus; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles | 2011 |
Nausea, vomiting, and diarrhea in a 9-year-old girl.
Topics: Antiparasitic Agents; Child; Cryptosporidiosis; Diarrhea; Feces; Female; Humans; Immunocompetence; Nausea; Nitro Compounds; Oocysts; Thiazoles; Vomiting | 2011 |
No reduction of HCV viral load in HIV patients co-infected with HCV genotype 1 during a 30 days course of nitazoxanide monotherapy.
Topics: Adult; Antiviral Agents; Coinfection; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Male; Middle Aged; Nitro Compounds; Pilot Projects; Thiazoles; Treatment Failure; Viral Load | 2011 |
Management of a Cryptosporidium hominis outbreak in a day-care center.
Topics: Animals; Antiparasitic Agents; Belgium; Child Day Care Centers; Child, Preschool; Cryptosporidiosis; Cryptosporidium; Diarrhea; Disease Outbreaks; Feces; Female; Humans; Hygiene; Infant; Infection Control; Male; Nitro Compounds; Paromomycin; Polymerase Chain Reaction; Thiazoles | 2012 |
Nitazoxanide suppresses IL-6 production in LPS-stimulated mouse macrophages and TG-injected mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Culture Techniques; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Injections, Intraperitoneal; Interleukin-6; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred Strains; Molecular Structure; Nitro Compounds; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Thioglycolates; Transcription, Genetic | 2012 |
Identification, characterization and cytotoxicity in vitro assay of nitazoxanide major degradation product.
Topics: Antiparasitic Agents; Cell Survival; Humans; Nitro Compounds; Safety; Thiazoles; Toxicity Tests | 2012 |
Validated and optimized high-performance liquid chromatographic determination of tizoxanide, the main active metabolite of nitazoxanide in human urine, plasma and breast milk.
Topics: Adult; Antiparasitic Agents; Chromatography, High Pressure Liquid; Female; Humans; Male; Milk, Human; Nitro Compounds; Thiazoles | 2012 |
Amixicile, a novel inhibitor of pyruvate: ferredoxin oxidoreductase, shows efficacy against Clostridium difficile in a mouse infection model.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Benzamides; Clostridioides difficile; Clostridium Infections; Disease Models, Animal; Enzyme Inhibitors; Fidaxomicin; Mice; Microbial Sensitivity Tests; Nitro Compounds; Pyruvate Synthase; Thiazoles; Treatment Outcome; Vancomycin | 2012 |
Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis.
Topics: Antiparasitic Agents; Autophagy; Cell Line; HEK293 Cells; Humans; Macrophages; Mechanistic Target of Rapamycin Complex 1; Monocytes; Multiprotein Complexes; Mycobacterium tuberculosis; NAD(P)H Dehydrogenase (Quinone); Nitro Compounds; Phagosomes; Proteins; Thiazoles; TOR Serine-Threonine Kinases; Tuberculosis | 2012 |
Successful use of nitazoxanide in the treatment of recurrent Clostridium difficile infection.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Humans; Male; Metronidazole; Nitro Compounds; Recurrence; Thiazoles; Vancomycin | 2011 |
Cryptosporidiosis in children following solid organ transplantation.
Topics: Antiparasitic Agents; Child; Child, Preschool; Cryptosporidiosis; Fluid Therapy; Humans; Nitro Compounds; Organ Transplantation; Thiazoles | 2012 |
Partial inhibition of aldose reductase by nitazoxanide and its molecular basis.
Topics: Aldehyde Reductase; Antiparasitic Agents; Humans; Kinetics; Models, Molecular; Nitro Compounds; Thiazoles | 2012 |
Vancomycin treatment's association with delayed intestinal tissue injury, clostridial overgrowth, and recurrence of Clostridium difficile infection in mice.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteroides; Cecum; Clostridioides difficile; Clostridium Infections; DNA, Bacterial; Enterocolitis, Pseudomembranous; Feces; Fidaxomicin; Intestines; Male; Metronidazole; Mice; Mice, Inbred C57BL; Nitro Compounds; Recurrence; Thiazoles; Treatment Outcome; Vancomycin | 2013 |
Quantitative screening for anticestode drugs based on changes in baseline enzyme secretion by Taenia crassiceps.
Topics: Alkaline Phosphatase; Animals; Anticestodal Agents; Artemisinins; Artesunate; Benzamides; Epilepsy; Glucose-6-Phosphate Isomerase; Humans; Imatinib Mesylate; Neurocysticercosis; Nitro Compounds; Parasitic Sensitivity Tests; Piperazines; Praziquantel; Protein Kinase Inhibitors; Pyrimidines; Taenia; Thiazoles | 2013 |
Assessment of Cryptosporidium parvum infection in immunocompetent and immunocompromised mice and its role in triggering intestinal dysplasia.
Topics: Animals; Antiparasitic Agents; Cryptosporidiosis; Cryptosporidium parvum; Cyclin D1; Disease Models, Animal; Female; Immunocompromised Host; Intestinal Mucosa; Intestines; Liver; Mice; Nitro Compounds; Oocysts; Thiazoles | 2013 |
Cryptosporidial infection in children with inflammatory bowel disease.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antiparasitic Agents; Case-Control Studies; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Cryptosporidiosis; Cryptosporidium; Diarrhea; Feces; Female; Humans; Immunosuppressive Agents; Male; Nitro Compounds; Patient Readmission; Recurrence; Retrospective Studies; Severity of Illness Index; Thiazoles | 2013 |
Enteroaggregative Escherichia coli strain in a novel weaned mouse model: exacerbation by malnutrition, biofilm as a virulence factor and treatment by nitazoxanide.
Topics: Animals; Biofilms; Colon; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Feces; Humans; Male; Malnutrition; Mice; Mice, Inbred C57BL; Nitro Compounds; Thiazoles; Virulence; Virulence Factors; Weaning | 2013 |
Activity of halogeno-thiazolides against Cryptosporidium parvum in experimentally infected immunosuppressed gerbils (Meriones unguiculatus).
Topics: Animals; Antiparasitic Agents; Cryptosporidiosis; Cryptosporidium parvum; Disease Models, Animal; Gerbillinae; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Nitro Compounds; Thiazoles; Treatment Outcome | 2013 |
Efficacy of nitazoxanide against clinical isolates of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitro Compounds; Sputum; Thiazoles; Tuberculosis, Pulmonary | 2013 |
Analysis of sequences of hepatitis C virus NS5A genotype 1 in HIV-coinfected patients with a null response to nitazoxanide or peg-interferon plus ribavirin.
Topics: Amino Acid Sequence; Antiviral Agents; Coinfection; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Interferons; Molecular Sequence Data; Nitro Compounds; Polyethylene Glycols; Ribavirin; Sequence Alignment; Sequence Analysis, DNA; Thiazoles; Treatment Failure; Viral Nonstructural Proteins | 2013 |
Metabolism of nitro drugs metronidazole and nitazoxanide in Giardia lamblia: characterization of a novel nitroreductase (GlNR2).
Topics: Antiprotozoal Agents; Cloning, Molecular; DNA Damage; Escherichia coli; Gene Expression; Gene Expression Profiling; Genes, Reporter; Giardia lamblia; Humans; Metronidazole; Nitric Oxide; Nitro Compounds; Nitroreductases; Parasitic Sensitivity Tests; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles | 2013 |
A c-Myc activation sensor-based high-throughput drug screening identifies an antineoplastic effect of nitazoxanide.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Heterografts; High-Throughput Screening Assays; Humans; Mice; Mice, Nude; Molecular Imaging; Neoplasm Transplantation; Nitro Compounds; Proto-Oncogene Proteins c-myc; Thiazoles | 2013 |
An extensive comparison of the effect of anthelmintic classes on diverse nematodes.
Topics: Albendazole; Animals; Anthelmintics; Cricetinae; Drug Resistance; Female; Ivermectin; Male; Mice; Nematoda; Nematode Infections; Nitro Compounds; Parasitic Sensitivity Tests; Pyrantel; Species Specificity; Thiazoles | 2013 |
Cryptosporidiosis-associated lymphocytic colitis.
Topics: Antiparasitic Agents; Biopsy; Colitis, Lymphocytic; Colonoscopy; Cryptosporidiosis; Humans; Male; Middle Aged; Missouri; Nitro Compounds; Thiazoles | 2013 |
Thiazolides, a new class of antiviral agents effective against rotavirus infection, target viral morphogenesis, inhibiting viroplasm formation.
Topics: Animals; Antiviral Agents; Cell Line; Haplorhini; Humans; Inclusion Bodies, Viral; Microbial Sensitivity Tests; Nitro Compounds; Protein Binding; Rotavirus; Thiazoles; Viral Nonstructural Proteins; Virus Assembly; Virus Replication | 2013 |
Effect of nitaxozanide and pyrimethamine on astrocytes infected by Toxoplasma gondii in vitro.
Topics: Animals; Antiparasitic Agents; Astrocytes; Cell Survival; Cells, Cultured; Female; Folic Acid Antagonists; Humans; Mice; Middle Aged; Nitro Compounds; Pyrimethamine; Rats; Rats, Wistar; Thiazoles; Toxoplasma; Toxoplasmosis | 2013 |
Identification of PPARγ ligands with One-dimensional Drug Profile Matching.
Topics: Animals; Benzophenones; Blood Glucose; Bromobenzenes; Cell Line, Tumor; Computer Simulation; Databases, Pharmaceutical; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Design; Drugs, Generic; Glucose Clamp Technique; Humans; Insulin; Ligands; Male; Nitro Compounds; PPAR gamma; Rats; Rats, Wistar; Thiazoles; Time Factors | 2013 |
Lethal action of the nitrothiazolyl-salicylamide derivative nitazoxanide via induction of oxidative stress in Leishmania (L.) infantum.
Topics: Antiprotozoal Agents; Cell Membrane; Cell Membrane Permeability; Inhibitory Concentration 50; Leishmania infantum; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Mitochondrial Membranes; Nitro Compounds; Oxidative Stress; Parasitic Sensitivity Tests; Reactive Oxygen Species; Thiazoles | 2013 |
Synthesis and antiprotozoal activity of nitazoxanide-N-methylbenzimidazole hybrids.
Topics: Antiprotozoal Agents; Benzimidazoles; Drug Design; Entamoeba histolytica; Eukaryota; Giardia lamblia; Nitro Compounds; Thiazoles; Trichomonas vaginalis | 2013 |
Effect of nitazoxanide on erythrocytes.
Topics: Annexin A5; Antiparasitic Agents; Calcium; Ceramides; Erythrocytes; Hemoglobins; Hemolysis; Humans; Nitro Compounds; Phosphatidylserines; Thiazoles | 2014 |
Combination therapy with nitazoxanide and amphotericin B, Glucantime®, miltefosine and sitamaquine against Leishmania (Leishmania) infantum intracellular amastigotes.
Topics: Aminoquinolines; Amphotericin B; Animals; Antiprotozoal Agents; Drug Combinations; Leishmania infantum; Leishmaniasis, Visceral; Macrophages, Peritoneal; Meglumine; Meglumine Antimoniate; Mice; Nitro Compounds; Organometallic Compounds; Parasitic Sensitivity Tests; Phosphorylcholine; Thiazoles | 2014 |
Treatment failure in patients with chronic Blastocystis infection.
Topics: Adolescent; Adult; Antiprotozoal Agents; Blastocystis; Blastocystis Infections; Child; Chronic Disease; Cohort Studies; DNA, Protozoan; Drug Therapy, Combination; Feces; Female; Furazolidone; Genotype; Humans; Male; Metronidazole; Middle Aged; Nitro Compounds; Sequence Analysis, DNA; Thiazoles; Treatment Failure; Young Adult | 2014 |
Validated stability indicating RP-HPLC for quantitation of nitazoxanide in presence of its alkaline degradation products and their characterization by HPLC-tandem mass spectrometry.
Topics: Acetonitriles; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Hydrolysis; Limit of Detection; Nitro Compounds; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry; Thiazoles | 2014 |
Comparative study between the effect of nitazoxanide and paromomycine in treatment of cryptosporidiosis in hospitalized children.
Topics: Animals; Child, Preschool; Cryptosporidiosis; Female; Hospitalization; Humans; Infant; Male; Nitro Compounds; Paromomycin; Rural Population; Thiazoles; Urban Population | 2013 |
Fascioliasis and intestinal parasitoses affecting schoolchildren in Atlixco, Puebla State, Mexico: epidemiology and treatment with nitazoxanide.
Topics: Adolescent; Anthelmintics; Child; Fascioliasis; Feeding Behavior; Female; Helminthiasis; Humans; Intestinal Diseases; Intestinal Diseases, Parasitic; Male; Mexico; Nitro Compounds; Parasitology; Prevalence; Risk Factors; Thiazoles; Treatment Outcome | 2013 |
Fascioliasis: a rare cause of liver abscess.
Topics: Abdominal Pain; Aged; Animals; Antiparasitic Agents; Cholangiography; Fasciola hepatica; Fascioliasis; Female; Humans; Liver Abscess; Nausea; Nitro Compounds; Praziquantel; Thiazoles; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
Nitazoxanide: nematicidal mode of action and drug combination studies.
Topics: Albendazole; Animals; Anthelmintics; Caenorhabditis elegans; Chloride Channels; Drug Synergism; Nitro Compounds; Pyrantel; Thiazoles | 2014 |
Nitazoxanide inhibits the replication of Japanese encephalitis virus in cultured cells and in a mouse model.
Topics: Animals; Antiviral Agents; Cell Line; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis Virus, Japanese; Encephalitis, Japanese; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Nitro Compounds; Survival Analysis; Thiazoles; Treatment Outcome; Viral Load; Virus Replication | 2014 |
Identification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria box.
Topics: Antiprotozoal Agents; Cryptosporidium parvum; Drug Repositioning; Humans; Hydroxyquinolines; Nitro Compounds; Quinazolines; Thiazoles; Toxoplasma | 2014 |
Could nitazoxanide be added to other essential medicines for integrated neglected tropical disease control and elimination?
Topics: Antiparasitic Agents; Communicable Disease Control; Disease Eradication; Humans; Neglected Diseases; Nitro Compounds; Parasitic Diseases; Thiazoles; Tropical Climate | 2014 |
Encapsulation of the antimicrobial and immunomodulator agent nitazoxanide within polymeric micelles.
Topics: Anti-Infective Agents; Crystallization; Diffusion; Immunologic Factors; Materials Testing; Micelles; Molecular Conformation; Nanocapsules; Nitro Compounds; Particle Size; Polymers; Surface Properties; Thiazoles | 2014 |
Structure-function relationship of thiazolide-induced apoptosis in colorectal tumor cells.
Topics: Antineoplastic Agents; Antiparasitic Agents; Apoptosis; Benzamides; Caco-2 Cells; Caspases; Colorectal Neoplasms; Glutathione S-Transferase pi; Halogenation; Humans; Models, Molecular; Nitro Compounds; Structure-Activity Relationship; Thiazoles | 2014 |
[Effect of different drugs on Echinococcus multilocularis metacestodes in vitro ].
Topics: Albendazole; Animals; Anticestodal Agents; Drug Therapy, Combination; Echinococcosis; Echinococcus multilocularis; Female; Gerbillinae; Hep G2 Cells; Humans; Itraconazole; Mice; Mice, Inbred BALB C; Nitro Compounds; Thiazoles | 2011 |
Fighting influenza--a new weapon in the armoury?
Topics: Anti-Infective Agents; Female; Humans; Influenza, Human; Male; Nitro Compounds; Thiazoles | 2014 |
Nitazoxanide for the treatment of infectious diarrhoea in the Northern Territory, Australia 2007-2012.
Topics: Adolescent; Anti-Infective Agents; Child; Dehydration; Dysentery; Female; Humans; Male; Native Hawaiian or Other Pacific Islander; Nitro Compounds; Northern Territory; Socioeconomic Factors; Thiazoles; Thinness | 2014 |
Nitazoxanide, an antiviral thiazolide, depletes ATP-sensitive intracellular Ca(2+) stores.
Topics: Adenosine Triphosphate; Animals; Antiviral Agents; Calcium; Cell Line; Cytoplasm; Diarrhea Virus 1, Bovine Viral; Endoplasmic Reticulum; Glycosylation; Humans; Nitro Compounds; Protein Transport; Thiazoles; Tumor Protein, Translationally-Controlled 1; Virus Replication | 2014 |
Action of nitroheterocyclic drugs against Clostridium difficile.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Drug Resistance, Bacterial; Drug Tolerance; Gene Expression Profiling; Microbial Viability; Mutation; Nitro Compounds; Nitrofurans; Nitroimidazoles; Nitroso Compounds; Serial Passage; Stress, Physiological; Thiazoles | 2014 |
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.
Topics: Albendazole; Antiprotozoal Agents; Axenic Culture; Cysteine; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Escherichia coli; Gene Expression; Giardia lamblia; Humans; Metronidazole; Mutation; Nitro Compounds; Omeprazole; Parasitic Sensitivity Tests; Protozoan Proteins; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles; Triose-Phosphate Isomerase; Trophozoites | 2014 |
Prevalence, clinical presentation and treatment outcome of cryptosporidiosis in immunocompetent adult patients presenting with acute diarrhoea.
Topics: Acute Disease; Adult; Animals; Antiparasitic Agents; Cryptosporidiosis; Diarrhea; Female; Humans; Male; Middle Aged; Nitro Compounds; Pakistan; Prevalence; Prospective Studies; Thiazoles; Treatment Outcome | 2014 |
Short communication: Nitazoxanide inhibits HIV viral replication in monocyte-derived macrophages.
Topics: Anti-HIV Agents; Antigens, CD; Antiprotozoal Agents; APOBEC-3G Deaminase; CD4 Antigens; Cells, Cultured; Cytidine Deaminase; Down-Regulation; Drug Repositioning; GPI-Linked Proteins; HIV-1; Humans; Macrophages; Nitro Compounds; Proteins; Receptors, CCR5; Thiazoles; Up-Regulation; Virus Replication | 2015 |
Synergistic effect of nitazoxanide with neuraminidase inhibitors against influenza A viruses in vitro.
Topics: Antiviral Agents; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H7N1 Subtype; Neuraminidase; Nitro Compounds; Oseltamivir; Thiazoles; Zanamivir | 2015 |
A screen of the NIH Clinical Collection small molecule library identifies potential anti-coronavirus drugs.
Topics: Animals; Antiviral Agents; Cell Line; Coronavirus; Drug Discovery; Harringtonines; Hexachlorophene; Homoharringtonine; Humans; Luciferases; Mice; Murine hepatitis virus; Nitro Compounds; Small Molecule Libraries; Thiazoles; Viral Load; Virus Internalization; Virus Replication | 2015 |
Identification of Nitazoxanide as a Group I Metabotropic Glutamate Receptor Negative Modulator for the Treatment of Neuropathic Pain: An In Silico Drug Repositioning Study.
Topics: Animals; Computational Biology; Computer Simulation; Drug Repositioning; Excitatory Amino Acid Antagonists; High-Throughput Screening Assays; Male; Neuralgia; Nitro Compounds; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Sciatic Neuropathy; Structure-Activity Relationship; Thiazoles | 2015 |
In vivo and in vitro efficacies of mebendazole, mefloquine and nitazoxanide against cyst echinococcosis.
Topics: Animals; Cysts; Echinococcosis; Echinococcus granulosus; Humans; Larva; Liver; Mebendazole; Mefloquine; Mice; Nitro Compounds; Thiazoles | 2015 |
Antiprotozoal Nitazoxanide Derivatives: Synthesis, Bioassays and QSAR Study Combined with Docking for Mechanistic Insight.
Topics: Antiprotozoal Agents; Entamoeba histolytica; Entamoebiasis; Humans; Molecular Docking Simulation; Nitro Compounds; Pyruvate Synthase; Quantitative Structure-Activity Relationship; Thiazoles | 2015 |
Liver Lesions, Fever and Eosinophilia Caused by Fasciola hepatica in a 15-year-old Girl.
Topics: Adolescent; Animals; Antiparasitic Agents; Cholangiopancreatography, Endoscopic Retrograde; Diagnosis, Differential; Eosinophilia; Fasciola hepatica; Fascioliasis; Female; Fever; Humans; Liver Diseases, Parasitic; Liver Function Tests; Nitro Compounds; Thiazoles; Tomography, X-Ray Computed | 2015 |
Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer.
Topics: Administration, Oral; Animals; Anthelmintics; Antineoplastic Agents; Cell Culture Techniques; Cell Hypoxia; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Repositioning; Drug Screening Assays, Antitumor; Female; Green Fluorescent Proteins; HCT116 Cells; HT29 Cells; Humans; Mice, Inbred Strains; Mice, Nude; Microscopy, Fluorescence; Nitro Compounds; Oxidative Phosphorylation; Signal Transduction; Spheroids, Cellular; Thiazoles; Xenograft Model Antitumor Assays | 2015 |
Combined flubendazole-nitazoxanide treatment of cystic echinococcosis: Pharmacokinetic and efficacy assessment in mice.
Topics: Albendazole; Animals; Antinematodal Agents; Antiparasitic Agents; Drug Therapy, Combination; Echinococcosis; Echinococcus; Echinococcus granulosus; In Vitro Techniques; Mebendazole; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Nitro Compounds; Thiazoles | 2015 |
Increased incidence of nitroimidazole-refractory giardiasis at the Hospital for Tropical Diseases, London: 2008-2013.
Topics: Adult; Albendazole; Antiprotozoal Agents; Drug Resistance; Female; Giardia lamblia; Giardiasis; Hospitals; Humans; Incidence; London; Male; Nitro Compounds; Nitroimidazoles; Quinacrine; Retrospective Studies; Thiazoles; Travel; Treatment Failure | 2015 |
Metabolism of nitazoxanide in rats, pigs, and chickens: Application of liquid chromatography coupled to hybrid linear ion trap/Orbitrap mass spectrometer.
Topics: Animals; Chickens; Chromatography, Liquid; Limit of Detection; Linear Models; Male; Mass Spectrometry; Nitro Compounds; Rats; Rats, Wistar; Reproducibility of Results; Swine; Thiazoles | 2015 |
Anaerobic respiration: In vitro efficacy of Nitazoxanide against mitochondriate Acanthamoeba castellanii of the T4 genotype.
Topics: Acanthamoeba castellanii; Acanthamoeba Keratitis; Anaerobiosis; Antiparasitic Agents; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Genotype; Humans; Microvessels; Nitro Compounds; Peptide Hydrolases; Proteolysis; Pyruvate Synthase; Thiazoles | 2015 |
Prophylactic Effect of BIO-1211 Small-Molecule Antagonist of VLA-4 in the EAE Mouse Model of Multiple Sclerosis.
Topics: Animals; Blood-Brain Barrier; CD11b Antigen; Cell Movement; Cerebral Cortex; Cytokines; Disease Models, Animal; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Gene Expression Regulation; Inflammation Mediators; Integrin alpha4beta1; Leukocyte Common Antigens; Leukocytes; Male; Mice; Monocytes; Multiple Sclerosis; Nitro Compounds; Oligopeptides; Permeability; RNA, Messenger; Thiazoles | 2015 |
Moderating effects of age, gender and education on the associations of perceived neighborhood environment attributes with accelerometer-based physical activity: The IPEN adult study.
Topics: Accelerometry; Adolescent; Adult; Age Factors; Aged; China; Cross-Sectional Studies; Educational Status; Environmental Health; Europe; Exercise; Female; Health Knowledge, Attitudes, Practice; Health Policy; Humans; Male; Middle Aged; New Zealand; Nitro Compounds; Residence Characteristics; Sex Factors; Surveys and Questionnaires; Thiazoles; United States; Young Adult | 2015 |
Assessment of the activity of directly acting antivirals and other products against different genotypes of hepatitis C virus prevalent in resource-poor countries.
Topics: Antiviral Agents; Catechin; Food Additives; Genotype; Hepacivirus; Hepatitis C; Humans; Nitro Compounds; Prevalence; Silybin; Silymarin; Thiazoles; Virus Replication | 2016 |
Advances Toward a Norovirus Antiviral: From Classical Inhibitors to Lethal Mutagenesis.
Topics: Antiparasitic Agents; Antiviral Agents; Caliciviridae Infections; Gastroenteritis; Humans; Mutagenesis; Nitro Compounds; Norovirus; Thiazoles; Viral Vaccines; Virus Replication | 2016 |
Validation of housekeeping genes as an internal control for gene expression studies in Giardia lamblia using quantitative real-time PCR.
Topics: Animals; Antiprotozoal Agents; DNA Primers; Gene Expression Regulation; Genes, Essential; Giardia lamblia; Metronidazole; Nitro Compounds; Real-Time Polymerase Chain Reaction; Thiazoles | 2016 |
Nitazoxanide Inhibits Pilus Biogenesis by Interfering with Folding of the Usher Protein in the Outer Membrane.
Topics: Animals; Antiparasitic Agents; Bacterial Secretion Systems; Cloning, Molecular; Erythrocytes; Escherichia coli Proteins; Fimbriae, Bacterial; Gene Expression; Guinea Pigs; Hemagglutination Tests; Humans; Molecular Chaperones; Nitro Compounds; Plasmids; Protein Conformation, beta-Strand; Protein Folding; Protein Multimerization; Protein Subunits; Thiazoles; Uropathogenic Escherichia coli | 2016 |
Nitazoxanide Analogues as Antimicrobial Agents Against Nosocomial Pathogens.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Cross Infection; Gram-Negative Bacteria; Gram-Positive Endospore-Forming Rods; Microbial Sensitivity Tests; Nitro Compounds; Phthalimides; Structure-Activity Relationship; Sulfonamides; Thiazoles | 2016 |
Cocrystals and alloys of nitazoxanide: enhanced pharmacokinetics.
Topics: Alloys; Animals; Calorimetry, Differential Scanning; Crystallization; Crystallography, X-Ray; Nitro Compounds; Rats; Rats, Sprague-Dawley; Thiazoles | 2016 |
Proteomic and ultrastructural analysis of the effect of a new nitazoxanide-N-methyl-1H-benzimidazole hybrid against Giardia intestinalis.
Topics: Antiprotozoal Agents; Benzimidazoles; Gene Expression; Giardia lamblia; Giardiasis; Nitro Compounds; Organ Specificity; Proteome; Protozoan Proteins; Thiazoles; Trophozoites | 2016 |
Simultaneous quantification of tizoxanide and tizoxanide glucuronide in mouse plasma by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Antiparasitic Agents; Chromatography, Liquid; Glucuronides; Limit of Detection; Male; Mice; Mice, Inbred ICR; Nitro Compounds; Tandem Mass Spectrometry; Thiazoles | 2016 |
Activity of nitazoxanide and tizoxanide against Mycobacterium tuberculosis in vitro and in whole blood culture.
Topics: Antitubercular Agents; Blood Culture; Dose-Response Relationship, Drug; Humans; Mycobacterium tuberculosis; Nitro Compounds; Protein Binding; Serum Albumin; Serum Albumin, Human; Serum Bactericidal Test; Thiazoles; Time Factors | 2016 |
Luteolin Impacts on the DNA Damage Pathway in Oral Squamous Cell Carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; DNA Damage; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Luteolin; Mouth Neoplasms; Nitro Compounds; Thiazoles; Thioxanthenes; Tyrphostins | 2016 |
Inhalable Particles for "Pincer Therapeutics" Targeting Nitazoxanide as Bactericidal and Host-Directed Agent to Macrophages in a Mouse Model of Tuberculosis.
Topics: Administration, Inhalation; Animals; Antitubercular Agents; Autophagy; Cell Line; Humans; Isoniazid; Macrophages; Male; Mice; Nitro Compounds; Radiotherapy Planning, Computer-Assisted; Rifabutin; Thiazoles; Tuberculosis | 2016 |
Ruling out nosocomial transmission of Cryptosporidium in a renal transplantation unit: case report.
Topics: Acute Kidney Injury; Adult; Animals; Coccidiostats; Cross Infection; Cryptosporidiosis; Cryptosporidium; Diarrhea; Feces; Female; Humans; Immunocompromised Host; Kidney Transplantation; Male; Middle Aged; Nitro Compounds; Thiazoles | 2016 |
Nitazoxanide anthelmintic activity against the enteral and parenteral phases of trichinellosis in experimentally infected rats.
Topics: Animals; Anthelmintics; Immunohistochemistry; Inflammation; Intestine, Small; Larva; Male; Muscles; Nitric Oxide Synthase Type II; Nitro Compounds; Rats; Specific Pathogen-Free Organisms; Thiazoles; Trichinella spiralis; Trichinellosis | 2016 |
Quantitative structure activity relationship (QSAR) studies on nitazoxanide-based analogues against Clostridium difficile In vitro.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Drug Design; Microbial Sensitivity Tests; Models, Molecular; Models, Statistical; Molecular Structure; Nitro Compounds; Quantitative Structure-Activity Relationship; Surface Properties; Thiazoles | 2016 |
Antiviral activities of niclosamide and nitazoxanide against chikungunya virus entry and transmission.
Topics: Animals; Antiviral Agents; Cell Line; Chikungunya Fever; Chikungunya virus; Drug Discovery; High-Throughput Screening Assays; Humans; Niclosamide; Nitro Compounds; Semliki forest virus; Sindbis Virus; Thiazoles; Virus Internalization; Virus Replication | 2016 |
Nitazoxanide induces in vitro metabolic acidosis in Taenia crassiceps cysticerci.
Topics: Albendazole; Animals; Anticestodal Agents; Antiparasitic Agents; Female; Glucose; Glycolysis; Lactic Acid; Mice; Mice, Inbred BALB C; Nitro Compounds; Pyruvic Acid; Taenia; Thiazoles | 2016 |
Fasciola hepatica infection in humans: overcoming problems for the diagnosis.
Topics: Animals; Fasciola hepatica; Fascioliasis; Feces; Humans; Middle Aged; Nitro Compounds; Thiazoles; Young Adult | 2016 |
Effect of Mass Stool Examination and Mass Treatment For Decreasing Intestinal Helminth and Protozoan Infection Rates in Bolivian Children: A Cross-Sectional Study.
Topics: Adolescent; Animals; Bolivia; Child; Child, Preschool; Cross-Sectional Studies; Entamoeba histolytica; Entamoebiasis; Feces; Female; Giardia lamblia; Giardiasis; Helminthiasis; Humans; Hymenolepiasis; Hymenolepis; Intestinal Diseases, Parasitic; Male; Mass Screening; Nitro Compounds; Prevalence; Protozoan Infections; Students; Thiazoles; Young Adult | 2016 |
Antiprotozoal drug nitazoxanide enhances parasitemia, tissue lesions and mortality caused by Trypanosoma cruzi in murine model.
Topics: Animals; Chagas Disease; Disease Models, Animal; Heart; Male; Mice, Inbred BALB C; Muscle, Striated; Myocardium; Nitro Compounds; Parasitemia; Thiazoles; Trypanocidal Agents; Trypanosoma cruzi | 2017 |
In vitro activity of nitazoxanide against some metronidazole-resistant and susceptible Trichomonas vaginalis isolates.
Topics: Adult; Drug Resistance, Bacterial; Female; Humans; Metronidazole; Nitro Compounds; Thiazoles; Trichomonas vaginalis; Trichomonas Vaginitis | 2017 |
Efficacy of nitazoxanide to treat natural Giardia infections in dogs.
Topics: Administration, Oral; Alanine Transaminase; Animals; Antiprotozoal Agents; Aspartate Aminotransferases; Cryptosporidiosis; Cryptosporidium; Dog Diseases; Dogs; Feces; Giardia; Giardiasis; Guanidines; Humans; Nitro Compounds; Praziquantel; Pyrantel Pamoate; Thiazoles | 2017 |
Coinfection with
Topics: Adult; Animals; Anthelmintics; Anti-HIV Agents; Antiprotozoal Agents; Coinfection; Diarrhea; Giardia lamblia; Giardiasis; HIV; HIV Infections; Humans; Hymenolepiasis; Hymenolepis diminuta; Hymenolepis nana; Male; Metronidazole; Nitro Compounds; Praziquantel; Thiazoles; Treatment Outcome; Weight Loss | 2017 |
Pharmacokinetics, Metabolism, and Partial Biodistribution of "Pincer Therapeutic" Nitazoxanide in Mice following Pulmonary Delivery of Inhalable Particles.
Topics: Administration, Inhalation; Animals; Chromatography, High Pressure Liquid; Dry Powder Inhalers; Half-Life; Lactic Acid; Lung; Macrophages, Alveolar; Male; Mice; Nitro Compounds; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tandem Mass Spectrometry; Thiazoles; Tissue Distribution | 2017 |
Nitazoxanide Is an Ineffective Treatment of Chronic Norovirus in Patients With X-Linked Agammaglobulinemia and May Yield False-Negative Polymerase Chain Reaction Findings in Stool Specimens.
Topics: Agammaglobulinemia; Antiviral Agents; Caliciviridae Infections; Genetic Diseases, X-Linked; Humans; Mutagenesis; Nitro Compounds; Norovirus; Polymerase Chain Reaction; Thiazoles | 2017 |
Reply to Kempf et al.
Topics: Agammaglobulinemia; Genetic Diseases, X-Linked; Humans; Nitro Compounds; Norovirus; Polymerase Chain Reaction; Thiazoles | 2017 |
Using a health-rating system to evaluate the usefulness of Caenorhabditis elegans as a model for anthelmintic study.
Topics: Albendazole; Animals; Anthelmintics; Caenorhabditis elegans; Helminthiasis; Humans; Inhibitory Concentration 50; Ivermectin; Lethal Dose 50; Nitro Compounds; Parasitic Sensitivity Tests; Pyrantel; Thiazoles | 2017 |
Synthesis, in vitro and in vivo giardicidal activity of nitrothiazole-NSAID chimeras displaying broad antiprotozoal spectrum.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiprotozoal Agents; Drug Design; Female; Giardia lamblia; Giardiasis; Humans; Leishmania; Mice; Nitro Compounds; Protozoan Infections; Thiazoles; Trichomonas vaginalis; Trypanosoma cruzi | 2017 |
Atorvastatin repurposing for the treatment of cryptosporidiosis in experimentally immunosuppressed mice.
Topics: Animals; Antiparasitic Agents; Atorvastatin; Colon; Cryptosporidiosis; Drug Synergism; Duodenum; Feces; Gallbladder; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileum; Immunosuppression Therapy; Jejunum; Lung; Male; Mice; Nitro Compounds; Stomach; Tablets; Thiazoles | 2017 |
Rotavirus Infection in Pediatric Allogeneic Hematopoietic Cell Transplant Recipients: Clinical Course and Experience Using Nitazoxanide and Enterally Administered Immunoglobulins.
Topics: Administration, Oral; Adolescent; Antiparasitic Agents; Child; Child, Preschool; Cohort Studies; Feces; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunization, Passive; Immunoglobulins; Infant; Male; Nitro Compounds; Retrospective Studies; Rotavirus; Rotavirus Infections; Thiazoles; Treatment Outcome; Young Adult | 2018 |
The unintended mitochondrial uncoupling effects of the FDA-approved anti-helminth drug nitazoxanide mitigates experimental parkinsonism in mice.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Line, Tumor; Cell Respiration; Drug Approval; Helminths; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neurons; Nitro Compounds; Parkinsonian Disorders; Rats; Reactive Oxygen Species; Thiazoles; United States; United States Food and Drug Administration | 2017 |
Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis.
Topics: Anti-Bacterial Agents; Down-Regulation; Drug Resistance, Bacterial; Humans; Mycobacterium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Mycobacterium smegmatis; Nitro Compounds; Nitroreductases; Thiazoles | 2017 |
Nitazoxanide is active against Mycobacterium leprae.
Topics: Animals; Anti-Bacterial Agents; Leprosy; Mice; Microbial Sensitivity Tests; Mycobacterium leprae; Nitro Compounds; Thiazoles | 2017 |
Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44.
Topics: Antiparasitic Agents; Female; Gene Expression Regulation; HEK293 Cells; Humans; Male; Mutation, Missense; Nitro Compounds; Pedigree; Receptors, Metabotropic Glutamate; Signal Transduction; Spinocerebellar Ataxias; Thiazoles | 2017 |
Drug susceptibility testing in microaerophilic parasites: Cysteine strongly affects the effectivities of metronidazole and auranofin, a novel and promising antimicrobial.
Topics: Albendazole; Animals; Anti-Infective Agents; Antiparasitic Agents; Antiprotozoal Agents; Antirheumatic Agents; Auranofin; Culture Media; Cysteine; Entamoeba histolytica; Furazolidone; Giardia lamblia; Metronidazole; Nitro Compounds; Parasites; Parasitic Sensitivity Tests; Thiazoles; Trichomonas vaginalis | 2017 |
In vivo treatment with nitazoxanide induces anaerobic metabolism in experimental intraperitoneal cysticercosis.
Topics: Anaerobiosis; Animals; Anticestodal Agents; Chromatography, High Pressure Liquid; Cysticercosis; Energy Metabolism; Female; Glucose; Host-Parasite Interactions; Ketoglutaric Acids; Lactic Acid; Mice; Mice, Inbred BALB C; Nitro Compounds; Taenia; Thiazoles | 2017 |
Opposing Effects of Nitazoxanide on Murine and Human Norovirus.
Topics: Agammaglobulinemia; Animals; Caliciviridae Infections; Genetic Diseases, X-Linked; Humans; Mice; Nitro Compounds; Norovirus; Polymerase Chain Reaction; Thiazoles | 2017 |
The therapeutic efficacy of azithromycin and nitazoxanide in the acute pig model of Cryptosporidium hominis.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Antiparasitic Agents; Azithromycin; Cryptosporidiosis; Cryptosporidium; Disease Models, Animal; Drug Therapy, Combination; Nitro Compounds; Sus scrofa; Swine; Thiazoles; Treatment Outcome | 2017 |
Inhibition of rubella virus replication by the broad-spectrum drug nitazoxanide in cell culture and in a patient with a primary immune deficiency.
Topics: A549 Cells; Animals; Antigens, Viral; Antiviral Agents; Cell Survival; Chlorocebus aethiops; Female; Granuloma; Human Umbilical Vein Endothelial Cells; Humans; Immunologic Deficiency Syndromes; Inhibitory Concentration 50; Nitro Compounds; Protein Transport; Rubella; Rubella virus; Skin; Thiazoles; Treatment Outcome; Vero Cells; Virus Replication | 2017 |
The susceptibility of circulating human influenza viruses to tizoxanide, the active metabolite of nitazoxanide.
Topics: Animals; Antiviral Agents; Cell Survival; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Lethal Dose 50; Madin Darby Canine Kidney Cells; Neuraminidase; Neutralization Tests; Nitro Compounds; Reproducibility of Results; Sensitivity and Specificity; Thiazoles | 2017 |
Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer.
Topics: Animals; Antineoplastic Agents; beta Catenin; Cell Line, Tumor; Citrullination; Colonic Neoplasms; Gene Knockout Techniques; Humans; Nitro Compounds; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Thiazoles; Wnt Signaling Pathway | 2018 |
Laser-responsive liposome for selective tumor targeting of nitazoxanide nanoparticles.
Topics: Animals; Antiparasitic Agents; Lasers; Liposomes; Mice; Nanoparticles; Neoplasms; Nitro Compounds; Particle Size; Thiazoles | 2018 |
Nitazoxanide May Modify the Course of Progressive Multifocal Leukoencephalopathy.
Topics: Adolescent; Adult; Antiparasitic Agents; Antiviral Agents; Brain; Epilepsy; Female; Humans; Immunologic Deficiency Syndromes; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Nitro Compounds; Polyomavirus; Polyomavirus Infections; Skin; Thiazoles | 2018 |
Protein disulfide isomerases as potential therapeutic targets for influenza A and B viruses.
Topics: A549 Cells; Animals; Antiviral Agents; Catechin; Dogs; Drug Discovery; High-Throughput Screening Assays; Host-Pathogen Interactions; Humans; Influenza A virus; Influenza B virus; Isoenzymes; Madin Darby Canine Kidney Cells; Nitro Compounds; Parabens; Protein Disulfide-Isomerases; Quercetin; RNA, Small Interfering; RNA, Viral; Sesquiterpenes; Thiazoles | 2018 |
Herbicidins from Streptomyces sp. CB01388 Showing Anti- Cryptosporidium Activity.
Topics: Anti-Bacterial Agents; Biological Products; Cell Line; Cell Line, Tumor; Cryptosporidium parvum; HEK293 Cells; Hep G2 Cells; Humans; Nitro Compounds; Purine Nucleosides; Streptomyces; Thiazoles | 2018 |
Inhibition of vaccinia virus replication by nitazoxanide.
Topics: Antiviral Agents; Cells, Cultured; Fibroblasts; Humans; Nitro Compounds; Thiazoles; Vaccinia virus; Virus Replication | 2018 |
Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus.
Topics: Antiviral Agents; Drug Discovery; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza, Human; Nitro Compounds; Thiazoles | 2018 |
Successful treatment of chronic norovirus gastroenteritis with nitazoxanide in a pediatric kidney transplant recipient.
Topics: Adolescent; Antiviral Agents; Caliciviridae Infections; Chronic Disease; Gastroenteritis; Humans; Kidney Transplantation; Male; Nitro Compounds; Norovirus; Postoperative Complications; Thiazoles | 2018 |
Physiological aspects of nitro drug resistance in Giardia lamblia.
Topics: Antiparasitic Agents; Antiprotozoal Agents; Drug Resistance; Giardia lamblia; Giardiasis; Metronidazole; Nitro Compounds; Nitroreductases; Oxidoreductases; Oxygen; Thiazoles; Trophozoites | 2018 |
Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57.
Topics: A549 Cells; Animals; Binding Sites; Humans; Nitro Compounds; Oxidoreductases; Paramyxoviridae; Paramyxoviridae Infections; Protein Disulfide-Isomerases; Protein Folding; Protein Transport; Thiazoles; Viral Fusion Proteins; Virus Replication | 2018 |
Nitazoxanide Inhibits Human Norovirus Replication and Synergizes with Ribavirin by Activation of Cellular Antiviral Response.
Topics: Antiviral Agents; Caco-2 Cells; Caliciviridae Infections; Cell Line; Cell Line, Tumor; Drug Synergism; Gastroenteritis; HEK293 Cells; Humans; Interferon Regulatory Factor-1; Intestines; Janus Kinases; Nitro Compounds; Norovirus; Organoids; Replicon; Ribavirin; STAT1 Transcription Factor; Thiazoles; Virus Replication | 2018 |
Potential Therapeutic Agents for Feline Calicivirus Infection.
Topics: Animals; Antiviral Agents; Caliciviridae Infections; Calicivirus, Feline; Cat Diseases; Cats; Cell Line; Cytidine; DNA-Directed RNA Polymerases; Epithelial Cells; Flavones; Gene Expression; High-Throughput Screening Assays; Inhibitory Concentration 50; Nitro Compounds; Peptide Hydrolases; Polyproteins; Pyridoxal Phosphate; Recombinant Proteins; Respiratory Tract Infections; Sulfonic Acids; Thiazoles | 2018 |
Nitazoxanide Is a Therapeutic Option for Adenovirus-Related Enteritis in Immunocompromised Adults.
Topics: Adenoviridae; Adenoviridae Infections; Adult; Antiviral Agents; Diarrhea; Drug Administration Schedule; Enteritis; Humans; Immunocompromised Host; Male; Nitro Compounds; Thiazoles; Treatment Outcome | 2018 |
Amixicile Reduces Severity of Cryptosporidiosis but Does Not Have
Topics: Animals; Antiprotozoal Agents; Benzamides; Cryptosporidiosis; Cryptosporidium parvum; Disease Models, Animal; Mice, Inbred C57BL; Nitro Compounds; Pyruvate Synthase; Thiazoles; Weight Loss | 2018 |
Nitazoxanide, an antiprotozoal drug, inhibits late-stage autophagy and promotes ING1-induced cell cycle arrest in glioblastoma.
Topics: Animals; Antiprotozoal Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line; Cell Line, Tumor; Cell Proliferation; Chloroquine; Glioblastoma; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Inhibitor of Growth Protein 1; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthyridines; Nitro Compounds; Protein Processing, Post-Translational; Thiazoles; Transcription, Genetic; Up-Regulation | 2018 |
Oral nitazoxanide treatment of experimental neurocysticercosis induces gluconeogenesis in Taenia crassiceps cysticerci.
Topics: Administration, Oral; Animals; Anthelmintics; Chromatography, High Pressure Liquid; Cysticercus; Energy Metabolism; Fatty Acids; Gluconeogenesis; Glucose; Lactic Acid; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Neurocysticercosis; Nitro Compounds; Oxaloacetic Acid; Oxidation-Reduction; Pyruvic Acid; Taenia; Thiazoles | 2019 |
Outcomes for Nitazoxanide Treatment in a Case Series of Patients with Primary Immunodeficiencies and Rubella Virus-Associated Granuloma.
Topics: Adolescent; Child; Child, Preschool; Female; Granuloma; Humans; Immunologic Deficiency Syndromes; Infant; Male; Nitro Compounds; Retrospective Studies; Rubella; Rubella virus; T-Lymphocytes; Thiazoles; Vaccination | 2019 |
Disruption of HBx-DDB1 by NTZ: New Mechanistic Insight Into an Old Drug With Broad Anti-infective Activities.
Topics: Hepatitis B virus; Nitro Compounds; Thiazoles | 2019 |
Inhibition of HBV Transcription From cccDNA With Nitazoxanide by Targeting the HBx-DDB1 Interaction.
Topics: DNA-Binding Proteins; DNA, Circular; DNA, Viral; HEK293 Cells; Hep G2 Cells; Hepatitis B virus; Hepatocytes; High-Throughput Screening Assays; Humans; Nitro Compounds; Protein Binding; Proteolysis; RNA, Messenger; RNA, Viral; Thiazoles; Trans-Activators; Transcription, Genetic; Viral Regulatory and Accessory Proteins | 2019 |
Evaluation of nitazoxanide as a novel drug for the treatment of acute and chronic toxoplasmosis.
Topics: Acute Disease; Animals; Antiparasitic Agents; Chronic Disease; Disease Models, Animal; Mice; Nitro Compounds; Thiazoles; Toxoplasma; Toxoplasmosis | 2019 |
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antiparasitic Agents; Cells, Cultured; Disease Models, Animal; Humans; Learning; Memory Disorders; Mice; Nitro Compounds; Thiazoles | 2019 |
The small molecule nitazoxanide selectively disrupts BAM-mediated folding of the outer membrane usher protein.
Topics: Antiparasitic Agents; Bacterial Outer Membrane Proteins; Escherichia coli Proteins; Molecular Chaperones; Nitro Compounds; Protein Folding; Thiazoles; Uropathogenic Escherichia coli | 2019 |
Inhibitory Effects of Antiviral Drug Candidates on Canine Parvovirus in F81 cells.
Topics: Animals; Antiviral Agents; Dog Diseases; Dogs; Drug Evaluation, Preclinical; Nitro Compounds; Parvoviridae Infections; Parvovirus, Canine; Salicylanilides; Thiazoles | 2019 |
A comprehensive characterization of chronic norovirus infection in immunodeficient hosts.
Topics: Adult; Antigens, CD19; Antiviral Agents; B-Lymphocytes; Caliciviridae Infections; Cells, Cultured; Common Variable Immunodeficiency; Enterocolitis; Female; Humans; Immunocompromised Host; Male; Middle Aged; Nitro Compounds; Norovirus; Programmed Cell Death 1 Receptor; Recurrence; Ribavirin; Species Specificity; T-Lymphocytes; Thiazoles; Treatment Outcome; Up-Regulation | 2019 |
Giardiasis: report of a case refractory to treatment.
Topics: Adult; Albendazole; Antiprotozoal Agents; Furazolidone; Giardia lamblia; Giardiasis; Humans; Male; Metronidazole; Nitro Compounds; Nitroimidazoles; Thiazoles; Tinidazole; Treatment Failure | 2019 |
Evaluation of nitazoxanide treatment following triclabendazole failure in an outbreak of human fascioliasis in Upper Egypt.
Topics: Adolescent; Adult; Animals; Antibodies, Helminth; Antiparasitic Agents; Child; Child, Preschool; Egypt; Eosinophilia; Fasciola; Fascioliasis; Female; Humans; Male; Middle Aged; Nitro Compounds; Prospective Studies; Thiazoles; Treatment Failure; Triclabendazole | 2019 |
Analysis of tizoxanide, active metabolite of nitazoxanide, in rat brain tissue and plasma by UHPLC-MS/MS.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Limit of Detection; Linear Models; Male; Nitro Compounds; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Thiazoles; Tissue Distribution | 2020 |
In vitro nitazoxanide exposure affects energetic metabolism of Taenia crassiceps.
Topics: Albendazole; Analysis of Variance; Animals; Anthelmintics; Antiparasitic Agents; Citrates; Citric Acid Cycle; Culture Media; Cysticercus; Energy Metabolism; Fumarates; Ketoglutaric Acids; Malates; Neurocysticercosis; Nitro Compounds; Oxaloacetic Acid; Succinic Acid; Taenia; Thiazoles | 2020 |
Astrovirus Replication Is Inhibited by Nitazoxanide
Topics: Animals; Astroviridae Infections; Caco-2 Cells; Cell Survival; Diarrhea; Enterocolitis, Necrotizing; Humans; Mamastrovirus; Nitro Compounds; Poultry; Thiazoles; Virus Replication | 2020 |
Nitazoxanide: Jack of All, Master of None?
Topics: Child; Humans; Nitro Compounds; Parasitic Diseases; Thiazoles | 2020 |
Antifilarial effect of nanocomposite of silver nanoparticles with nitazoxanide against the microfilariae of Setaria cervi-infected albino rats.
Topics: Animals; Diethylcarbamazine; Disease Models, Animal; Drug Compounding; Drug Synergism; Filaricides; Host-Parasite Interactions; Male; Metal Nanoparticles; Nanocomposites; Nitro Compounds; Rats; Setaria Nematode; Setariasis; Silver; Thiazoles | 2020 |
Characterisation of the in vitro activity of a Nitazoxanide-N-methyl-1H-benzimidazole hybrid molecule against albendazole and nitazoxanide susceptible and resistant strains of Giardia intestinalis and its in vivo giardicidal activity.
Topics: Albendazole; Animals; Antiprotozoal Agents; Cytoskeletal Proteins; Fluorescent Antibody Technique, Indirect; Giardia lamblia; Humans; Mice; Nitro Compounds; Parasitic Sensitivity Tests; Thiazoles; Time Factors | 2020 |
Prophylaxis of ferrets with nitazoxanide and oseltamivir combinations is more effective at reducing the impact of influenza a virus infection compared to oseltamivir monotherapy.
Topics: Administration, Oral; Animals; Antiviral Agents; Chemoprevention; Dogs; Drug Combinations; Drug Resistance, Viral; Female; Ferrets; Influenza A Virus, H1N1 Subtype; Lung; Madin Darby Canine Kidney Cells; Male; Nitro Compounds; Orthomyxoviridae Infections; Oseltamivir; Thiazoles; Virus Shedding | 2020 |
Histopathologic evaluation of experimental murine neurocysticercosis after treatment with albendazole/nitazoxanide combination.
Topics: Albendazole; Animals; Anticestodal Agents; Disease Models, Animal; Drug Combinations; Female; Mice; Mice, Inbred BALB C; Neurocysticercosis; Nitro Compounds; Taenia; Thiazoles | 2020 |
Synthetic antiprotozoal thiazolide drug induced apoptosis in colorectal cancer cells: implications of IL-6/JAK2/STAT3 and p53/caspases-dependent signaling pathways based on molecular docking and in vitro study.
Topics: Antineoplastic Agents; Antiprotozoal Agents; Apoptosis; Caspases; Cell Cycle; Cell Survival; Colorectal Neoplasms; Cytochromes c; Fluorouracil; HCT116 Cells; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Interleukin-6; Janus Kinase 2; Molecular Docking Simulation; Nitro Compounds; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; STAT3 Transcription Factor; Thiazoles; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2020 |
Nitazoxanide/azithromycin combination for COVID-19: A suggested new protocol for early management.
Topics: Antiparasitic Agents; Antiviral Agents; Azithromycin; Betacoronavirus; Coronavirus Infections; COVID-19; Drug Therapy, Combination; Humans; Nitro Compounds; Pandemics; Pneumonia, Viral; SARS-CoV-2; Thiazoles | 2020 |
In Vitro Data of Current Therapies for SARS-CoV-2.
Topics: Adenosine Monophosphate; Alanine; Betacoronavirus; China; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Emetine; Homoharringtonine; Humans; Hydroxychloroquine; Ivermectin; Lopinavir; Nitro Compounds; Pandemics; Pneumonia, Viral; SARS-CoV-2; Teicoplanin; Thiazoles | 2020 |
Therapeutic potential of Nitazoxanide against Newcastle disease virus: A possible modulation of host cytokines.
Topics: Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Chick Embryo; Chickens; Cytokines; Gene Expression; Newcastle Disease; Newcastle disease virus; Nitro Compounds; Poultry Diseases; Thiazoles; Virus Replication | 2020 |
Nanodelivery of nitazoxanide: impact on the metabolism of
Topics: Animals; Cysticercus; Mice; Mice, Inbred BALB C; Neurocysticercosis; Nitro Compounds; Taenia; Thiazoles | 2020 |
Boosting bladder cancer treatment by intravesical nitazoxanide and bacillus calmette-guérin association.
Topics: Adjuvants, Immunologic; Administration, Intravesical; Animals; BCG Vaccine; Drug Combinations; Female; Nitro Compounds; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder Neoplasms | 2021 |
Anti-infective nitazoxanide disrupts transcription of ribosome biogenesis-related genes in yeast.
Topics: Anti-Infective Agents; High-Throughput Nucleotide Sequencing; Killer Factors, Yeast; Nitro Compounds; Ribosomes; RNA Precursors; RNA-Seq; RNA, Double-Stranded; Saccharomyces cerevisiae; Thiazoles; Transcriptome | 2020 |
Host-targeted nitazoxanide has a high barrier to resistance but does not reduce the emergence or proliferation of oseltamivir-resistant influenza viruses in vitro or in vivo when used in combination with oseltamivir.
Topics: Animals; Antiviral Agents; Cell Proliferation; Dogs; Drug Resistance, Viral; Drug Therapy, Combination; Female; Ferrets; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Male; Nitro Compounds; Orthomyxoviridae Infections; Oseltamivir; Thiazoles | 2020 |
Nitazoxanide protects cats from feline calicivirus infection and acts synergistically with mizoribine in vitro.
Topics: Animals; Antiviral Agents; Caliciviridae Infections; Calicivirus, Feline; Cat Diseases; Cats; Cell Line; Drug Synergism; Female; Lung; Nitro Compounds; Ribonucleosides; Thiazoles; Trachea; Viral Load; Virus Shedding | 2020 |
Repurposing of host-based therapeutic agents for the treatment of coronavirus disease 2019 (COVID-19): a link between antiviral and anticancer mechanisms?
Topics: Anticholesteremic Agents; Antineoplastic Agents; Antiparasitic Agents; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Drug Administration Schedule; Drug Repositioning; Host-Pathogen Interactions; Humans; Hypoglycemic Agents; Ivermectin; Lovastatin; Metformin; Nitro Compounds; Pandemics; Pneumonia, Viral; SARS-CoV-2; Severity of Illness Index; Thiazoles | 2020 |
In Vivo Treatment with the Combination of Nitazoxanide and Flubendazole Induces Gluconeogenesis and Protein Catabolism in Taenia crassiceps cysticerci.
Topics: Animals; Cysticercus; Gluconeogenesis; Mebendazole; Mice; Mice, Inbred BALB C; Nitro Compounds; Swine; Taenia solium; Thiazoles | 2021 |
Synergistic tumor inhibition of colon cancer cells by nitazoxanide and obeticholic acid, a farnesoid X receptor ligand.
Topics: Animals; beta Catenin; Carcinogenesis; Cell Proliferation; Chenodeoxycholic Acid; Colonic Neoplasms; Drug Synergism; Gene Expression Regulation, Neoplastic; HCT116 Cells; Heterografts; Humans; Ligands; Liver; Mice; Molecular Targeted Therapy; Nitro Compounds; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles | 2021 |
Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
Topics: Adult; Antiviral Agents; Computer Simulation; COVID-19; COVID-19 Drug Treatment; Drug Dosage Calculations; Drug Repositioning; Female; Humans; Lung; Male; Middle Aged; Models, Biological; Nitro Compounds; Reproducibility of Results; Thiazoles; Tissue Distribution; Young Adult | 2021 |
Targeting intracellular Leishmania (L.) infantum with nitazoxanide entrapped into phosphatidylserine-nanoliposomes: An experimental study.
Topics: Animals; Antiprotozoal Agents; Dynamic Light Scattering; Female; Inhibitory Concentration 50; Intracellular Space; Leishmania infantum; Liposomes; Macrophages; Male; Mesocricetus; Mice, Inbred BALB C; Nanoparticles; Nitro Compounds; Phosphatidylserines; Scattering, Small Angle; Static Electricity; Thiazoles; X-Ray Diffraction | 2020 |
The unusual experience of managing a severe COVID-19 case at home: what can we do and where do we go?
Topics: Adrenal Cortex Hormones; Ambulatory Care; Antiparasitic Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Enoxaparin; Female; Humans; Middle Aged; Nitro Compounds; Oxygen Inhalation Therapy; Pandemics; Pneumonia, Viral; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; SARS-CoV-2; Severity of Illness Index; Telemedicine; Thiazoles; Thorax; Tomography, X-Ray Computed | 2020 |
Enhancing the solubility of nitazoxanide with solid dispersions technique: formulation, evaluation, and cytotoxicity study.
Topics: Calorimetry, Differential Scanning; Drug Carriers; HEK293 Cells; Humans; Nitro Compounds; Pharmaceutical Preparations; Solubility; Spectroscopy, Fourier Transform Infrared; Thiazoles | 2021 |
Available drugs and supplements for rapid deployment for treatment of COVID-19.
Topics: Adenosine Monophosphate; Alanine; Animals; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Drug Repositioning; Flavonoids; Humans; Mice; Nitro Compounds; Pharmaceutical Preparations; SARS-CoV-2; Small Molecule Libraries; Teicoplanin; Thiazoles | 2021 |
Potential role for nitazoxanide in treating SARS-CoV-2 infection.
Topics: Antiviral Agents; COVID-19; Humans; Nitro Compounds; SARS-CoV-2; Thiazoles | 2020 |
[2020: Evidence-Based Medicine odyssey. The fall and rise of evidence-based medicine in the year of coronavirus.]
Topics: Access to Information; Antiviral Agents; Brazil; Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Disclosure; Evidence-Based Medicine; Humans; Hydroxychloroquine; Italy; Nitro Compounds; Pandemics; Politics; Propaganda; SARS-CoV-2; Thiazoles; United States | 2021 |
56-Year-Old Man With Profuse Diarrhea.
Topics: alpha 1-Antitrypsin; Colonoscopy; Cryptosporidiosis; Diagnosis, Differential; Diarrhea; Feces; Humans; Hypoalbuminemia; Immunocompromised Host; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Nitro Compounds; Protein-Losing Enteropathies; Thiazoles; Travel | 2021 |
The immunomodulatory activity of secnidazole-nitazoxanide in a murine cryptosporidiosis model.
Topics: Animals; Antiprotozoal Agents; Cryptosporidiosis; Cryptosporidium parvum; Cytokines; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Ileum; Immunocompromised Host; Immunomodulation; Male; Metronidazole; Mice; Nitro Compounds; Parasite Load; Thiazoles | 2021 |
Transmucosal Delivery of Self-Assembling Photosensitizer-Nitazoxanide Nanocomplexes with Fluorinated Chitosan for Instillation-Based Photodynamic Therapy of Orthotopic Bladder Tumors.
Topics: Chitosan; Humans; Nitro Compounds; Photochemotherapy; Photosensitizing Agents; Thiazoles; Urinary Bladder Neoplasms | 2021 |
Case Report: Two Cases of Cryptosporidiosis in Heavily Pretreated Patients With Myeloma.
Topics: Antiparasitic Agents; Combined Modality Therapy; Cryptosporidiosis; Cryptosporidium; Diarrhea; Disease Management; Disease Susceptibility; Female; Humans; Male; Middle Aged; Multiple Myeloma; Nitro Compounds; Retreatment; Symptom Assessment; Thiazoles; Tomography, X-Ray Computed; Treatment Outcome | 2021 |
Human Astroviruses: A Tale of Two Strains.
Topics: Anti-Infective Agents; Astroviridae; Astroviridae Infections; Caco-2 Cells; Cell Line, Tumor; Central Nervous System; Humans; Nitro Compounds; Phylogeny; RNA, Viral; Thiazoles; Virus Replication | 2021 |
Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry.
Topics: Antiparasitic Agents; Antiviral Agents; Cloning, Molecular; COVID-19; Drug Repositioning; Enzyme Assays; Enzyme Inhibitors; Escherichia coli; Exoribonucleases; Gene Expression; Genetic Vectors; High-Throughput Screening Assays; Humans; Kinetics; Mass Spectrometry; Methylation; Nitro Compounds; Prescription Drugs; Recombinant Fusion Proteins; RNA Caps; RNA, Viral; SARS-CoV-2; Small Molecule Libraries; Thiazoles; Viral Nonstructural Proteins; Virus Replication | 2021 |
MDR1 protein (ABC-C1) Over Expression in Giardia Intestinalis Incubated with Albendazole and Nitazoxanide.
Topics: Albendazole; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Giardia lamblia; Giardiasis; Mice; Nitro Compounds; Thiazoles | 2021 |
Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.
Topics: Animals; Antineoplastic Agents; Antiparasitic Agents; Dose-Response Relationship, Drug; Female; HEK293 Cells; Humans; Lysosomes; Mice; Mice, Inbred BALB C; Mice, Nude; Mitophagy; Nitro Compounds; Reactive Oxygen Species; Thiazoles; Urinary Bladder Neoplasms | 2021 |
Antitumor Activity of Nitazoxanide against Colon Cancers: Molecular Docking and Experimental Studies Based on Wnt/β-Catenin Signaling Inhibition.
Topics: Animals; Antiparasitic Agents; Apoptosis; beta Catenin; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3 beta; HCT116 Cells; Humans; Male; Mice; Molecular Docking Simulation; Nitro Compounds; Proliferating Cell Nuclear Antigen; Thiazoles; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2021 |
Synthesis, in vitro bioassays, and computational study of heteroaryl nitazoxanide analogs.
Topics: Amides; Anti-Bacterial Agents; Antineoplastic Agents; Antiparasitic Agents; Bacterial Proteins; Biological Assay; Cell Survival; Escherichia coli; HeLa Cells; Humans; Mitogen-Activated Protein Kinase 9; Molecular Docking Simulation; Nitro Compounds; Tetrahydrofolate Dehydrogenase; Thiazoles; Thymidylate Synthase | 2021 |
NSAIDs/nitazoxanide/azithromycin repurposed for COVID-19: potential mitigation of the cytokine storm interleukin-6 amplifier via immunomodulatory effects.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; COVID-19; COVID-19 Drug Treatment; Cytokine Release Syndrome; Drug Repositioning; Humans; Interferons; Interleukin-6; Nitro Compounds; Observational Studies as Topic; SARS-CoV-2; Thiazoles | 2022 |
Alterations in Taenia crassiceps cysticerci cytoskeleton induced by nitazoxanide and flubendazole.
Topics: Animals; Cysticercosis; Cysticercus; Cytoskeleton; Female; Mebendazole; Mice; Mice, Inbred BALB C; Nitro Compounds; Taenia; Thiazoles | 2021 |
Nitazoxanide induced myocardial injury in zebrafish embryos by activating oxidative stress response.
Topics: Animals; Animals, Genetically Modified; Apoptosis; Cardiotoxicity; Computational Biology; Disease Models, Animal; Disease Susceptibility; Embryo, Nonmammalian; Gene Expression Profiling; Gene Ontology; Heart Injuries; Myocytes, Cardiac; Nitro Compounds; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Thiazoles; Zebrafish | 2021 |
Effect of drug metabolism in the treatment of SARS-CoV-2 from an entirely computational perspective.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Design; Drug Discovery; Humans; Metabolic Networks and Pathways; Molecular Docking Simulation; Nitro Compounds; Pyrazines; Pyrrolidines; Ribavirin; SARS-CoV-2; Thiazoles | 2021 |
Feline Calicivirus Virulent Systemic Disease: Clinical Epidemiology, Analysis of Viral Isolates and In Vitro Efficacy of Novel Antivirals in Australian Outbreaks.
Topics: Animals; Antiviral Agents; Australia; Caliciviridae Infections; Calicivirus, Feline; Capsid; Cat Diseases; Cats; Cytidine; Disease Outbreaks; Female; Male; Metagenome; Nitro Compounds; Phylogeny; Thiazoles | 2021 |
African scientists race to test COVID drugs - but face major hurdles.
Topics: Africa; Amides; Amodiaquine; Artesunate; Atazanavir Sulfate; Carbamates; Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Cytidine; Drug Approval; Drug Evaluation, Preclinical; Drug Repositioning; Drug Therapy, Combination; Humans; Hydroxylamines; Imidazoles; Ivermectin; Naphthyridines; Nitro Compounds; Pregnenediones; Pyrazines; Pyrrolidines; Ritonavir; Sample Size; Thiazoles; Valine; World Health Organization | 2021 |
Changes in John Cunningham Virus Index in Multiple Sclerosis Patients Treated with Different Disease-Modifying Therapies.
Topics: Adult; Female; Humans; Immunologic Factors; JC Virus; Leukoencephalopathy, Progressive Multifocal; Longitudinal Studies; Male; Middle Aged; Multiple Sclerosis; Natalizumab; Nitro Compounds; Thiazoles | 2022 |
Antiparasitic and immunomodulating effects of nitazoxanide, ivermectin and selenium on Cryptosporidium infection in diabetic mice.
Topics: Animals; Antiparasitic Agents; Cryptosporidiosis; Cryptosporidium; Diabetes Mellitus, Experimental; Ivermectin; Mice; Nitro Compounds; Rodent Diseases; Selenium; Thiazoles | 2021 |
Intraperitoneal and intracranial experimental cysticercosis present different metabolic preferences after treatment with isolated or combined albendazole and nitazoxanide.
Topics: Albendazole; Animals; Cysticercosis; Cysticercus; Mice; Mice, Inbred BALB C; Nitro Compounds; Taenia; Thiazoles | 2022 |
Nitazoxanide and Cancer Drug Resistance: Targeting Wnt/β-catenin Signaling Pathway.
Topics: Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasms; Nitro Compounds; Thiazoles; Wnt Signaling Pathway | 2022 |
Nitazoxanide Exerts Immunomodulatory Effects on Peripheral Blood Mononuclear Cells from Type 2 Diabetes Patients.
Topics: Adult; Diabetes Mellitus, Type 2; Humans; Leukocytes, Mononuclear; MicroRNAs; Nitro Compounds; Thiazoles | 2021 |
Nitazoxanide treatment for norovirus infection in solid organ transplant recipients.
Topics: Caliciviridae Infections; Humans; Nitro Compounds; Organ Transplantation; Thiazoles; Transplant Recipients | 2022 |
Nitazoxanide and related thiazolides induce cell death in cancer cells by targeting the 20S proteasome with novel binding modes.
Topics: Animals; Antineoplastic Agents; Caco-2 Cells; Cell Death; Dose-Response Relationship, Drug; Drug Delivery Systems; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nitro Compounds; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Thiazoles | 2022 |
Impairment of SARS-CoV-2 spike glycoprotein maturation and fusion activity by nitazoxanide: an effect independent of spike variants emergence.
Topics: Antiviral Agents; COVID-19 Drug Treatment; Humans; Nitro Compounds; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Thiazoles | 2022 |
In vitro metabolic stress induced by nitazoxanide and flubendazole combination in Taenia crassiceps cysticerci.
Topics: Animals; Antiparasitic Agents; Cysticercosis; Cysticercus; Mebendazole; Mice; Mice, Inbred BALB C; Nitro Compounds; Stress, Physiological; Taenia; Thiazoles | 2022 |
Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Colorectal Neoplasms; Humans; Liver Neoplasms; Mitochondria; Nitro Compounds; Sorafenib; Thiazoles | 2022 |
Nitazoxanide potentiates linezolid against linezolid-resistant Staphylococcus aureus in vitro and in vivo.
Topics: Anti-Bacterial Agents; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Nitro Compounds; Staphylococcal Infections; Staphylococcus aureus; Thiazoles | 2022 |
Pre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2.
Topics: Animals; Antiviral Agents; COVID-19 Drug Treatment; Cricetinae; Humans; Nitro Compounds; SARS-CoV-2; Thiazoles | 2022 |
A specific turn-on fluorescence probe for determination of nitazoxanide based on feasible oxidation reaction with hypochlorite: Applying cobalt ferrite nanoparticles for pre-concentration and extraction of its metabolite from real urine samples.
Topics: Cobalt; Ferric Compounds; Fluorescent Dyes; Humans; Hypochlorous Acid; Nanoparticles; Nitro Compounds; Oxidation-Reduction; Thiazoles | 2022 |
A real world multi center study on efficacy and safety of natalizumab in Indian patients with multiple sclerosis.
Topics: Adolescent; Adult; Female; Humans; Immunologic Factors; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Nitro Compounds; Thiazoles | 2022 |
Blockage of Wnt/β-catenin Signaling Pathway in Colorectal Cancer Resistant Cells by Nitazoxanide Effects on Peptidylarginine Deiminases Expression.
Topics: Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Humans; Nitro Compounds; Oxaliplatin; Protein-Arginine Deiminases; Thiazoles; Wnt Signaling Pathway | 2022 |
Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) and Natalizumab Serum Concentration as Potential Biomarkers for Pharmacodynamics and Treatment Response of Patients with Multiple Sclerosis Receiving Natalizumab.
Topics: Biomarkers; Humans; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Nitro Compounds; Retrospective Studies; Thiazoles; Vascular Cell Adhesion Molecule-1 | 2022 |
Electronic Structures and Reactivities of COVID-19 Drugs: A DFT Study.
Topics: COVID-19 Drug Treatment; Electronics; Humans; Models, Molecular; Nitro Compounds; Quantum Theory; Solvents; Thiazoles; Water | 2022 |
A Turn-On-Type Fluorescence Resonance Energy Transfer Eco-friendly Method for Nitazoxanide Quantification in Pharmaceutical Dosage Form and Spiked Plasma: Evaluation of Greenness Profile Using Different Assessment Tools.
Topics: Coloring Agents; Fluorescence Resonance Energy Transfer; Humans; Nitro Compounds; Pharmaceutical Preparations; Thiazoles | 2023 |
The African Kelleni's roadmap using nitazoxanide and broad-spectrum antimicrobials to abort returning to COVID-19 square one.
Topics: Anti-Infective Agents; COVID-19; Humans; Nitro Compounds; SARS-CoV-2; Thiazoles | 2023 |
Nitazoxanide Inhibits the Bifunctional Enzyme GlG6PD::6PGL of
Topics: Giardia lamblia; Giardiasis; Humans; Molecular Docking Simulation; Thiazoles | 2023 |