Page last updated: 2024-08-23

nitazoxanide and metronidazole

nitazoxanide has been researched along with metronidazole in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (1.96)	18.2507
2000's	18 (35.29)	29.6817
2010's	25 (49.02)	24.3611
2020's	7 (13.73)	2.80

Authors

Authors	Studies
Cremades, N; Croxen, MA; Harman, WD; Hoffman, PS; Morash, MG; Sisson, G; Welch, K	1
Hemphill, A; Müller, J; Müller, N; Sanderson, S; Wastling, J	1
Galang, MA; Gerding, DN; Hecht, DW; Johnson, S; Osmolski, JR; Sambol, SP	1
Argotte-Ramos, R; Cedillo-Rivera, R; Chan-Bacab, MJ; Chávez-Silva, F; Hernández-Nuñez, E; Moo-Puc, R; Navarrete-Vazquez, G; Rodríguez-Gutiérrez, Mdel C	1
Duque-Montaño, BE; Gómez-Caro, LC; Hernández-Baltazar, E; Monge, A; Rivera, G; Sanchez-Sanchez, M; Torres-Angeles, O	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chan-Bacab, MJ; Chávez-Silva, F; Díaz-Coutiño, D; Hernández-Núñez, E; Moo-Puc, R; Moreno-Díaz, H; Nava-Zuazo, C; Navarrete-Vázquez, G; Ortega-Morales, BO	1
Canul-Canché, J; Chávez-Silva, F; Colín-Lozano, B; Estrada-Soto, S; Guerrero-Álvarez, J; Hidalgo-Figueroa, S; Méndez, ST; Moo-Puc, R; Navarrete-Vázquez, G; Oria-Hernández, J; Ortiz-Andrade, R; Reyes-Vivas, H	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Argüello-Garcia, R; Barbosa-Cabrera, E; Chan-Bacab, MJ; Colín-Lozano, B; Hernández-Núñez, E; León-Rivera, I; López-Guerrero, V; Moo-Puc, R; Navarrete-Vázquez, G; Ortega-Morales, BO; Scior, T	1
Hart, CJS; Riches, A; Skinner-Adams, TS; Trenholme, KR	1
Cortés-Benítez, F; Palacios-Espinosa, JF; Pérez-Villanueva, J; Rodríguez-Villar, K; Soria-Arteche, O; Yépez-Mulia, L	1
Mégraud, F; Occhialini, A; Rossignol, JF	1
Vdovenko, AA; Williams, JE	1
McVay, CS; Rolfe, RD	1
Abboud, P; Ballet, JJ; Borsa-Lebas, F; Brasseur, P; Caron, F; Favennec, L; Gargala, G; Lemée, V	1
Ayoub, A; Chegne, NL; Favennec, L; Gargala, G; Ortiz, JJ	1
Berg, DE; Goodwin, A; Hoffman, PS; Hughes, NJ; Mukhopadhyay, AK; Raudonikiene, A; Sisson, G	1
Hemphill, A; Müller, J; Müller, N; Rossignol, JF; Rühle, G	1
Appelbaum, PC; Pankuch, GA	1
Dupont, HL; Gupta, A; Hamill, RJ; Lentnek, A; Logan, N; Musher, DM; Rossignol, JF	1
Bouza, E; Burillo, A; Muñoz, P	1
Koletar, SL; Mangino, JE; Stevenson, KB; Young, JD	1
Garud, S; Hamill, RJ; Logan, N; Mehendiratta, V; Melgarejo, NA; Musher, DM	1
Hemphill, A; Müller, J; Müller, N; Sterk, M	1
Bronze, MS; Greenfield, R; Greenfield, RA; Salvaggio, M; Sud, B	1
Felger, I; Hemphill, A; Ley, S; Müller, J; Müller, N	1
Hehl, A; Hemphill, A; Müller, J; Müller, N; Nillius, D	1
Burgess, AG; Dunn, LA; Kazimierczuk, Z; Krauer, KG; Upcroft, JA; Upcroft, P; Wright, JM	1
Baines, SD; Freeman, J; Huscroft, GS; Todhunter, SL; Wilcox, MH	1
Müller, J; Müller, N; Nillius, D	1
Davids, BJ; Dunn, L; Eckmann, L; Gillin, FD; Lauwaet, T; Millman, M; Miyamoto, Y; Tejman-Yarden, N; Upcroft, JA	1
Cheema, FH; Kanwal, S; Korsten, MA; Luthra, M; Majeed, UM; Rafiullah, F; Sohail, MR	1
Johnson, S; Venugopal, AA	1
Guerrant, RL; Hoffman, PS; Kolling, GL; Li, Y; Moore, JH; Riggins, MS; van Opstal, EJ; Warren, CA	1
Criollo, CP; Granados, CE; Reveiz, L; Uribe, LG	1
Müller, J; Müller, N; Schildknecht, P	1
Ellis, J; Harkness, J; Marriott, D; Roberts, T; Stark, D	1
Castillo-Villanueva, A; de la Mora-de la Mora, I; Enríquez-Flores, S; Figueroa-Salazar, R; García-Torres, I; Gómez-Manzo, S; Gutiérrez-Castrellón, P; Hernández-Alcántara, G; López-Velázquez, G; Marcial-Quino, J; Méndez, ST; Oria-Hernández, J; Reyes-Vivas, H; Torres-Arroyo, A; Vanoye-Carlo, A; Yépez-Mulia, L	1
Johnson, S; Soriano, MM	1
De la Mora-De la Mora, I; Enríquez-Flores, S; Fierro, F; Garcia-Torres, I; Gómez-Manzo, S; Marcial-Quino, J; Reyes-Vivas, H; Sierra-Palacios, E; Vanoye-Carlo, A	1
Abdel-Magied, AA; El-Henawy, AA; Hammouda, MM; Mosbah, A	1
Hernán, A; Jiménez, JC; Núñez, L; Pérez-Chacón, G; Pocaterra, LA; Rojas, E	1
Leitsch, D	1
Hemphill, A; Müller, J; Müller, N	1
Iza, JA; Iza, SN; Olivera, MJ	1
Cogdill, AG; Guevara, B	1
Abdel Kader, A; El Amir, A; Farid, A; Madbouly, N; Rabee, I	1
Agarwal, VK; Ashdhir, P; Chauhan, V; Goel, V; Jain, A; Jhajharia, A; Pokharna, R; Sharma, G	1
Abd-Elsalam, SM; Bahaa, MM; Baiomy, N; Elnaggar, MH; Elsawy, AA; Gamal, RM; Habba, E; Salamah, AM; Shawky, D	1
Muller, WJ; Newman, AM; Soneji, M; Toia, J	1

Reviews

8 review(s) available for nitazoxanide and metronidazole

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Anti- Journal of medicinal chemistry, 2020, 11-25, Volume: 63, Issue:22 Topics: Animals; Antiprotozoal Agents; Benzimidazoles; Drug Delivery Systems; Drug Discovery; Drug Therapy, Combination; Gastrointestinal Tract; Giardia; Giardiasis; Humans; Nitroimidazoles	2020
Antimicrobial therapy of Clostridium difficile-associated diarrhea. The Medical clinics of North America, 2006, Volume: 90, Issue:6 Topics: Aged; Anti-Infective Agents; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; Disease Outbreaks; Feces; Humans; Infant; Megacolon, Toxic; Metronidazole; Nitro Compounds; Risk Factors; Secondary Prevention; Thiazoles; Vancomycin	2006
Part XI. Trimethoprim-sulfamethoxazole, nitrofurantoin, chloramphenicol, metronidazole and tinidazole, rifaximin, and nitazoxanide. The Journal of the Oklahoma State Medical Association, 2007, Volume: 100, Issue:7 Topics: Anti-Bacterial Agents; Bacterial Infections; Chloramphenicol; Drug Resistance, Microbial; Humans; Metronidazole; Nitro Compounds; Nitrofurantoin; Rifamycins; Rifaximin; Thiazoles; Tinidazole; Trimethoprim, Sulfamethoxazole Drug Combination	2007
Current state of Clostridium difficile treatment options. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Volume: 55 Suppl 2 Topics: Anti-Bacterial Agents; Bacitracin; Clinical Trials as Topic; Clostridioides difficile; Clostridium Infections; Drug Resistance, Bacterial; Fusidic Acid; Humans; Metronidazole; Nitro Compounds; Secondary Prevention; Severity of Illness Index; Teicoplanin; Thiazoles; Treatment Outcome; Vancomycin	2012
Drugs for treating giardiasis. The Cochrane database of systematic reviews, 2012, Dec-12, Volume: 12 Topics: Adult; Albendazole; Antiparasitic Agents; Child; Giardiasis; Humans; Mebendazole; Metronidazole; Nitro Compounds; Randomized Controlled Trials as Topic; Thiazoles; Tinidazole	2012
Treatment of Clostridium difficile infections. Infectious disease clinics of North America, 2015, Volume: 29, Issue:1 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Drug Administration Schedule; Drug Therapy, Combination; Fidaxomicin; Gastrointestinal Diseases; Humans; Metronidazole; Nitro Compounds; Randomized Controlled Trials as Topic; Recurrence; Rifamycins; Rifaximin; Thiazoles; Vancomycin	2015
Helicobacter pylori: A Review of Current Diagnostic and Management Strategies. Digestive diseases and sciences, 2020, Volume: 65, Issue:7 Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antigens, Bacterial; Biopsy; Bismuth; Breath Tests; Clarithromycin; Culture Techniques; Doxycycline; Drug Resistance, Bacterial; Drug Therapy, Combination; Dyspepsia; Feces; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Lymphoma, B-Cell, Marginal Zone; Metronidazole; Nitro Compounds; Organometallic Compounds; Peptic Ulcer; Polymerase Chain Reaction; Proton Pump Inhibitors; Rifabutin; Salicylates; Salvage Therapy; Serologic Tests; Stomach Neoplasms; Tetracycline; Thiazoles; Treatment Outcome; Urea	2020

Trials

5 trial(s) available for nitazoxanide and metronidazole

Article	Year
Randomized clinical study of nitazoxanide compared to metronidazole in the treatment of symptomatic giardiasis in children from Northern Peru. Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:9 Topics: Anti-Infective Agents; Child; Child, Preschool; Diarrhea; Drug Administration Schedule; Female; Giardiasis; Humans; Male; Metronidazole; Nitro Compounds; Peru; Thiazoles; Treatment Outcome	2001
Nitazoxanide for the treatment of Clostridium difficile colitis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Aug-15, Volume: 43, Issue:4 Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Male; Metronidazole; Nitro Compounds; Thiazoles	2006
Clostridium difficile colitis that fails conventional metronidazole therapy: response to nitazoxanide. The Journal of antimicrobial chemotherapy, 2007, Volume: 59, Issue:4 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Male; Metronidazole; Middle Aged; Nitro Compounds; Recurrence; Thiazoles; Treatment Failure	2007
Evaluating the efficacy of nitazoxanide in uncomplicated amebic liver abscess. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2021, Volume: 40, Issue:3 Topics: Female; Humans; Lactation; Liver Abscess, Amebic; Metronidazole; Nitro Compounds; Pregnancy; Thiazoles	2021
Nitazoxanide-based therapeutic regimen as a novel treatment for Helicobacter pylori infection in children and adolescents: a randomized trial. European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:9 Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Child; Clarithromycin; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Metronidazole; Nitro Compounds; Proton Pump Inhibitors; Thiazoles; Treatment Outcome	2022

Other Studies

38 other study(ies) available for nitazoxanide and metronidazole

Article	Year
Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3 Topics: Acetyl Coenzyme A; Animals; Antiprotozoal Agents; Bacteria, Anaerobic; Campylobacter jejuni; Carbon Dioxide; Cloning, Molecular; Clostridium; Culture Media; Enzyme Inhibitors; Helicobacter pylori; Kinetics; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Nitro Compounds; Parasites; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction; Thiamine Pyrophosphate; Thiazoles	2007
A novel Giardia lamblia nitroreductase, GlNR1, interacts with nitazoxanide and other thiazolides. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Amino Acid Sequence; Animals; Antiparasitic Agents; Chromatography, Affinity; Enzyme Inhibitors; Giardia lamblia; Molecular Sequence Data; Nitro Compounds; Nitroreductases; Parasitic Sensitivity Tests; Protozoan Proteins; Thiazoles	2007
In vitro activities of 15 antimicrobial agents against 110 toxigenic clostridium difficile clinical isolates collected from 1983 to 2004. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8 Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous; Humans; Microbial Sensitivity Tests; United States	2007
Synthesis of benzologues of Nitazoxanide and Tizoxanide: a comparative study of their in vitro broad-spectrum antiprotozoal activity. Bioorganic & medicinal chemistry letters, 2011, May-15, Volume: 21, Issue:10 Topics: Antiprotozoal Agents; Giardia; Molecular Structure; Nitro Compounds; Plasmodium; Thiazoles; Trichomonas vaginalis	2011
Synthesis and in vitro evaluation of new ethyl and methyl quinoxaline-7-carboxylate 1,4-di-N-oxide against Entamoeba histolytica. Bioorganic & medicinal chemistry, 2013, Aug-01, Volume: 21, Issue:15 Topics: Antiprotozoal Agents; Cyclic N-Oxides; Entamoeba histolytica; Models, Molecular; Molecular Structure; Quinoxalines; Spectrum Analysis; Structure-Activity Relationship	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
2-acylamino-5-nitro-1,3-thiazoles: preparation and in vitro bioevaluation against four neglected protozoan parasites. Bioorganic & medicinal chemistry, 2014, Mar-01, Volume: 22, Issue:5 Topics: Animals; Antiprotozoal Agents; Drug Design; Humans; Protozoan Infections; Thiazoles	2014
Synthesis of nitro(benzo)thiazole acetamides and in vitro antiprotozoal effect against amitochondriate parasites Giardia intestinalis and Trichomonas vaginalis. Bioorganic & medicinal chemistry, 2015, May-01, Volume: 23, Issue:9 Topics: Acetamides; Animals; Antiprotozoal Agents; Benzothiazoles; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fructose-Bisphosphate Aldolase; Giardia lamblia; Molecular Dynamics Simulation; Molecular Structure; Nitro Compounds; Parasitic Sensitivity Tests; Structure-Activity Relationship; Thiazoles; Trichomonas vaginalis; Vero Cells	2015
Synthesis, in vitro and in vivo giardicidal activity of nitrothiazole-NSAID chimeras displaying broad antiprotozoal spectrum. Bioorganic & medicinal chemistry letters, 2017, 08-01, Volume: 27, Issue:15 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiprotozoal Agents; Drug Design; Female; Giardia lamblia; Giardiasis; Humans; Leishmania; Mice; Nitro Compounds; Protozoan Infections; Thiazoles; Trichomonas vaginalis; Trypanosoma cruzi	2017
The giardicidal activity of lobendazole, fabomotizole, tenatoprazole and ipriflavone: A ligand-based virtual screening and in vitro study. European journal of medicinal chemistry, 2021, Feb-05, Volume: 211 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antiprotozoal Agents; Benzimidazoles; Carbamates; Humans; In Vitro Techniques; Isoflavones; Ligands	2021
Nitazoxanide, a potential drug for eradication of Helicobacter pylori with no cross-resistance to metronidazole. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:11 Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Helicobacter Infections; Helicobacter pylori; Humans; Metronidazole; Nitro Compounds; Pilot Projects; Thiazoles	1998
Blastocystis hominis: neutral red supravital staining and its application to in vitro drug sensitivity testing. Parasitology research, 2000, Volume: 86, Issue:7 Topics: Amebicides; Animals; Blastocystis hominis; Chloroquine; Coloring Agents; Humans; Metronidazole; Neutral Red; Nitro Compounds; Parasitic Sensitivity Tests; Paromomycin; Quinacrine; Staining and Labeling; Sulfamethoxazole; Tetracycline; Thiazoles; Trimethoprim	2000
In vitro and in vivo activities of nitazoxanide against Clostridium difficile. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:9 Topics: Animals; Anti-Bacterial Agents; Clindamycin; Clostridioides difficile; Cricetinae; Disease Models, Animal; Enterocolitis, Pseudomembranous; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles; Vancomycin	2000
Successful treatment of metronidazole- and albendazole-resistant giardiasis with nitazoxanide in a patient with acquired immunodeficiency syndrome. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Jun-15, Volume: 32, Issue:12 Topics: Adult; AIDS-Related Opportunistic Infections; Albendazole; Animals; Antiprotozoal Agents; Drug Resistance, Microbial; Giardia lamblia; Giardiasis; Humans; Male; Metronidazole; Nitro Compounds; Thiazoles; Treatment Outcome	2001
Enzymes associated with reductive activation and action of nitazoxanide, nitrofurans, and metronidazole in Helicobacter pylori. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:7 Topics: Biotransformation; Cloning, Molecular; DNA Damage; Drug Resistance, Bacterial; Escherichia coli; Helicobacter pylori; Ketone Oxidoreductases; Metronidazole; Mutation; Nitro Compounds; Nitrofurans; Nitroreductases; Oxidation-Reduction; Pyruvate Synthase; Substrate Specificity; Thiazoles	2002
In vitro effects of thiazolides on Giardia lamblia WB clone C6 cultured axenically and in coculture with Caco2 cells. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:1 Topics: Animals; Caco-2 Cells; Coculture Techniques; Giardia lamblia; Giardiasis; Humans; Metronidazole; Nitro Compounds; Parasitic Sensitivity Tests; Thiazoles; Tissue Culture Techniques	2006
Activities of tizoxanide and nitazoxanide compared to those of five other thiazolides and three other agents against anaerobic species. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:3 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteria, Anaerobic; Clindamycin; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles	2006
Nitazoxanide versus metronidazole for Clostridium difficile-associated colitis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Jan-01, Volume: 44, Issue:1 Topics: Aged; Animals; Anti-Bacterial Agents; Clostridioides difficile; Cricetinae; Enterocolitis, Pseudomembranous; Female; Humans; Male; Metronidazole; Nitro Compounds; Thiazoles; Treatment Outcome	2007
Characterization of Giardia lamblia WB C6 clones resistant to nitazoxanide and to metronidazole. The Journal of antimicrobial chemotherapy, 2007, Volume: 60, Issue:2 Topics: Animals; Antiprotozoal Agents; Clone Cells; DNA Primers; Drug Resistance; Gene Expression Regulation; Giardia lamblia; Metronidazole; Nitro Compounds; Protein Disulfide-Isomerases; Pyruvate Oxidase; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Thiazoles	2007
Identification of differentially expressed genes in a Giardia lamblia WB C6 clone resistant to nitazoxanide and metronidazole. The Journal of antimicrobial chemotherapy, 2008, Volume: 62, Issue:1 Topics: Animals; Antigens, Protozoan; Antigens, Surface; Antiprotozoal Agents; Drug Resistance; Gene Expression Profiling; Giardia lamblia; Heat-Shock Proteins; Metronidazole; Mutation; Nitro Compounds; Nitroreductases; Oligonucleotide Array Sequence Analysis; Protein Disulfide-Isomerases; Protozoan Proteins; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles	2008
Stable expression of Escherichia coli beta-glucuronidase A (GusA) in Giardia lamblia: application to high-throughput drug susceptibility testing. The Journal of antimicrobial chemotherapy, 2009, Volume: 64, Issue:6 Topics: Animals; Antiprotozoal Agents; Drug Evaluation, Preclinical; Escherichia coli; Escherichia coli Proteins; Genes, Reporter; Giardia lamblia; Glucuronidase; Metronidazole; Microbial Sensitivity Tests; Microbial Viability; Nitro Compounds; Pharmaceutical Preparations; Recombinant Proteins; Thiazoles	2009
Susceptibility in vitro of clinically metronidazole-resistant Trichomonas vaginalis to nitazoxanide, toyocamycin, and 2-fluoro-2'-deoxyadenosine. Parasitology research, 2010, Volume: 107, Issue:4 Topics: Anaerobiosis; Antitrichomonal Agents; Deoxyadenosines; Drug Resistance; Female; Humans; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles; Toyocamycin; Trichomonas vaginalis; Trichomonas Vaginitis	2010
Nitazoxanide is active against Clostridium difficile strains with reduced susceptibility to metronidazole. The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:6 Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Drug Resistance, Bacterial; Humans; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles	2011
Nitroreductase (GlNR1) increases susceptibility of Giardia lamblia and Escherichia coli to nitro drugs. The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:5 Topics: Anti-Infective Agents; Escherichia coli; Giardia lamblia; Humans; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Nitroreductases; Oxidation-Reduction; Parasitic Sensitivity Tests; Thiazoles	2011
Impaired parasite attachment as fitness cost of metronidazole resistance in Giardia lamblia. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10 Topics: Animals; Antiprotozoal Agents; Cell Line; Drug Resistance; Furazolidone; Giardia lamblia; Giardiasis; Glucose; Metronidazole; Mice; Mice, Inbred C57BL; Nitro Compounds; Thiazoles; Tinidazole	2011
Successful use of nitazoxanide in the treatment of recurrent Clostridium difficile infection. BMJ case reports, 2011, Nov-21, Volume: 2011 Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Humans; Male; Metronidazole; Nitro Compounds; Recurrence; Thiazoles; Vancomycin	2011
Vancomycin treatment's association with delayed intestinal tissue injury, clostridial overgrowth, and recurrence of Clostridium difficile infection in mice. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteroides; Cecum; Clostridioides difficile; Clostridium Infections; DNA, Bacterial; Enterocolitis, Pseudomembranous; Feces; Fidaxomicin; Intestines; Male; Metronidazole; Mice; Mice, Inbred C57BL; Nitro Compounds; Recurrence; Thiazoles; Treatment Outcome; Vancomycin	2013
Metabolism of nitro drugs metronidazole and nitazoxanide in Giardia lamblia: characterization of a novel nitroreductase (GlNR2). The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:8 Topics: Antiprotozoal Agents; Cloning, Molecular; DNA Damage; Escherichia coli; Gene Expression; Gene Expression Profiling; Genes, Reporter; Giardia lamblia; Humans; Metronidazole; Nitric Oxide; Nitro Compounds; Nitroreductases; Parasitic Sensitivity Tests; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles	2013
Treatment failure in patients with chronic Blastocystis infection. Journal of medical microbiology, 2014, Volume: 63, Issue:Pt 2 Topics: Adolescent; Adult; Antiprotozoal Agents; Blastocystis; Blastocystis Infections; Child; Chronic Disease; Cohort Studies; DNA, Protozoan; Drug Therapy, Combination; Feces; Female; Furazolidone; Genotype; Humans; Male; Metronidazole; Middle Aged; Nitro Compounds; Sequence Analysis, DNA; Thiazoles; Treatment Failure; Young Adult	2014
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12 Topics: Albendazole; Antiprotozoal Agents; Axenic Culture; Cysteine; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Escherichia coli; Gene Expression; Giardia lamblia; Humans; Metronidazole; Mutation; Nitro Compounds; Omeprazole; Parasitic Sensitivity Tests; Protozoan Proteins; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles; Triose-Phosphate Isomerase; Trophozoites	2014
Validation of housekeeping genes as an internal control for gene expression studies in Giardia lamblia using quantitative real-time PCR. Gene, 2016, Apr-25, Volume: 581, Issue:1 Topics: Animals; Antiprotozoal Agents; DNA Primers; Gene Expression Regulation; Genes, Essential; Giardia lamblia; Metronidazole; Nitro Compounds; Real-Time Polymerase Chain Reaction; Thiazoles	2016
In vitro activity of nitazoxanide against some metronidazole-resistant and susceptible Trichomonas vaginalis isolates. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2017, Volume: 23, Issue:4 Topics: Adult; Drug Resistance, Bacterial; Female; Humans; Metronidazole; Nitro Compounds; Thiazoles; Trichomonas vaginalis; Trichomonas Vaginitis	2017
Coinfection with The American journal of tropical medicine and hygiene, 2017, Volume: 96, Issue:5 Topics: Adult; Animals; Anthelmintics; Anti-HIV Agents; Antiprotozoal Agents; Coinfection; Diarrhea; Giardia lamblia; Giardiasis; HIV; HIV Infections; Humans; Hymenolepiasis; Hymenolepis diminuta; Hymenolepis nana; Male; Metronidazole; Nitro Compounds; Praziquantel; Thiazoles; Treatment Outcome; Weight Loss	2017
Drug susceptibility testing in microaerophilic parasites: Cysteine strongly affects the effectivities of metronidazole and auranofin, a novel and promising antimicrobial. International journal for parasitology. Drugs and drug resistance, 2017, Volume: 7, Issue:3 Topics: Albendazole; Animals; Anti-Infective Agents; Antiparasitic Agents; Antiprotozoal Agents; Antirheumatic Agents; Auranofin; Culture Media; Cysteine; Entamoeba histolytica; Furazolidone; Giardia lamblia; Metronidazole; Nitro Compounds; Parasites; Parasitic Sensitivity Tests; Thiazoles; Trichomonas vaginalis	2017
Physiological aspects of nitro drug resistance in Giardia lamblia. International journal for parasitology. Drugs and drug resistance, 2018, Volume: 8, Issue:2 Topics: Antiparasitic Agents; Antiprotozoal Agents; Drug Resistance; Giardia lamblia; Giardiasis; Metronidazole; Nitro Compounds; Nitroreductases; Oxidoreductases; Oxygen; Thiazoles; Trophozoites	2018
Giardiasis: report of a case refractory to treatment. Le infezioni in medicina, 2019, Sep-01, Volume: 27, Issue:3 Topics: Adult; Albendazole; Antiprotozoal Agents; Furazolidone; Giardia lamblia; Giardiasis; Humans; Male; Metronidazole; Nitro Compounds; Nitroimidazoles; Thiazoles; Tinidazole; Treatment Failure	2019
The immunomodulatory activity of secnidazole-nitazoxanide in a murine cryptosporidiosis model. Journal of medical microbiology, 2021, Volume: 70, Issue:3 Topics: Animals; Antiprotozoal Agents; Cryptosporidiosis; Cryptosporidium parvum; Cytokines; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Ileum; Immunocompromised Host; Immunomodulation; Male; Metronidazole; Mice; Nitro Compounds; Parasite Load; Thiazoles	2021
Metronidazole for treatment of norovirus in pediatric transplant recipients. Pediatric transplantation, 2022, Volume: 26, Issue:8 Topics: Child; Chronic Disease; Diarrhea; Gastroenteritis; Humans; Metronidazole; Norovirus; Retrospective Studies; Transplant Recipients	2022