nisoxetine has been researched along with desipramine in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (23.21) | 18.7374 |
| 1990's | 20 (35.71) | 18.2507 |
| 2000's | 20 (35.71) | 29.6817 |
| 2010's | 3 (5.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Camp, VM; Chen, P; Ely, TD; Galt, J; Goodman, MM; Howell, L; Kilts, CD; Malveaux, G; Martarello, L; McConathy, J; Nemeroff, CB; Plisson, C; Shi, B; Votaw, JR | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Alfinito, P; Bray, J; Cohn, ST; Deecher, DC; Fensome, A; Johnston, G; Koury, E; Mahaney, PE; Marella, MA; McComas, CC; Nogle, L; Trybulski, EJ; Vu, AT; Ye, F; Zhang, P | 1 |
| Alfinito, P; Bray, JA; Coghlan, RD; Cosmi, SA; Deecher, DC; Heffernan, GD; Huselton, C; Johnston, GH; Kenney, T; Koury, E; Li, Y; Mahaney, PE; Manas, ES; McDevitt, RE; Robichaud, AJ; Trybulski, EJ; Winneker, RC | 1 |
| Bush, LR; Campbell, UC; Engel, SR; Hardy, LW; Hewitt, MC; Koch, P; Ma, J; Malcolm, SC; Saraswat, LD; Schreiber, R; Shao, L; Spear, KL; Spicer, NA; Varney, MA; Wang, F | 1 |
| Choi, K; Moon, B; Park, JE; Roh, EJ; Sim, T; Song, C | 1 |
| Schmidt, MJ; Thornberry, JF | 1 |
| Janowsky, A; Mishra, R; Sulser, F | 1 |
| Bymaster, FB; Fuller, RW; Perry, KW; Wong, DT | 1 |
| Bymaster, FP; Horng, JS; Wong, DT | 1 |
| Bauer, ME; Tejani-Butt, SM | 1 |
| Blum, B; Bönisch, H; Michael-Hepp, J | 1 |
| Bäckström, IT; Marcusson, JO | 1 |
| Gonzales, RA; Moerschbaecher, JM; Mosaddeghi, M | 1 |
| Bäckström, IT; Marcusson, JO; Ross, SB | 1 |
| Goldstein, FJ; Kellstein, DE; Malseed, RT; Ossipov, MH | 1 |
| Foley, AJ; Leedham, JA; Pennefather, JN | 1 |
| Abrahamsson, T; Carlsson, L | 1 |
| Carter, RB; Leander, JD | 1 |
| Jobe, PC; Ray, TB | 1 |
| Sugrue, MF | 1 |
| Tella, SR | 1 |
| Gackenheimer, SL; Gehlert, DR; Schober, DA | 1 |
| Goldberg, SR; Tella, SR | 1 |
| Chen, NH; Reith, ME | 1 |
| Bayer, BM; Berkeley, MB; Daussin, S; Hernandez, MC | 1 |
| Goldberg, SR; Schindler, CW; Tella, SR | 1 |
| Gackenheimer, SL; Gehlert, DR; Robertson, DW | 1 |
| Kurz, T; Offner, B; Richardt, G; Schömig, A; Schreieck, J; Tölg, R | 1 |
| Ordway, GA; Zhu, MY | 1 |
| Kleven, MS; Koek, W | 1 |
| Dailey, JW; Jobe, PC; Steenbergen, JL; Yan, QS | 1 |
| Apparsundaram, S; Blakely, RD; Ordway, GA; Zhu, MY | 1 |
| Chen, N; Justice, JB; Trowbridge, CG | 1 |
| Heal, DJ; Kilpatrick, IC; Needham, PL; Rowley, HL | 1 |
| Ferrel, A; Figlewicz, DP; Schaefer, J; Zavosh, A | 1 |
| De Oliveira, K; Hennings, EC; Kiss, JP; Toth, PT; Vizi, ES | 1 |
| Esteban, S; García-Sevilla, JA; Lladó, J; Sastre-Coll, A | 1 |
| Harkin, A; Nowak, G; Paul, IA | 1 |
| Elie, R; Habimana, A; Hébert, C; Reader, TA | 1 |
| Brodde, OE; Leineweber, K; Seyfarth, T | 1 |
| Bryan-Lluka, LJ; Paczkowski, FA | 1 |
| Bönisch, H; Bryan-Lluka, LJ; Paczkowski, FA | 1 |
| Bönisch, H; Bryan-Lluka, LJ; Paczkowski, FA; Runkel, F; Sucic, S | 1 |
| Bryan-Lluka, LJ; Sucic, S | 1 |
| Fujiwara, H; Iida, Y; Kanegawa, N; Kawashima, H; Kiyono, Y; Nishimura, H; Saji, H | 1 |
| Murray, K; Murray, M | 1 |
| Bianchi, M; Cavanni, P; Crespi, F; Faedo, S; Heidbreder, CA; Lacroix, LP; Perdona, E; Remelli, R | 1 |
| Altamirano, AV; Benmansour, S; Frazer, A; Gould, GG; Jones, DJ; Morilak, DA; Pardon, MC; Sanchez, TA | 1 |
| Hume, AS; Kyle, PB; Ordway, GA; Zhu, MY | 1 |
| Swant, J; Thompson, AM; Wagner, JJ | 1 |
| Fujibayashi, Y; Kanegawa, N; Kawashima, H; Kiyono, Y; Kuge, Y; Saji, H; Sugita, T; Ueda, M | 1 |
| Baros, AM; Bondi, CO; Lapiz, MD; Morilak, DA; O'Donnell, JM; Zhang, HT; Zhao, Z | 1 |
| Hirano, K; Hotta, Y; Kajiwara, Y; Kobayashi, Y; Sugimoto, Y; Tagawa, N; Yamada, J; Yamada, S | 1 |
| García-Fuster, MJ; García-Sevilla, JA | 1 |
1 review(s) available for nisoxetine and desipramine
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
55 other study(ies) available for nisoxetine and desipramine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Synthesis and characterization of iodine-123 labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane. A ligand for in vivo imaging of serotonin transporters by single-photon-emission tomography.
Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Female; HeLa Cells; Humans; Iodine Radioisotopes; Isotope Labeling; Ligands; Macaca fascicularis; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nortropanes; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2003 |
Synthesis and activity of 1-(3-amino-1-phenylpropyl)indolin-2-ones: a new class of selective norepinephrine reuptake inhibitors.
Topics: Humans; Indoles; Molecular Structure; Neurotransmitter Uptake Inhibitors; Norepinephrine; Stereoisomerism; Structure-Activity Relationship | 2008 |
Dual acting norepinephrine reuptake inhibitors and 5-HT(2A) receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles.
Topics: Biological Transport; Cell Line; Humans; Indoles; Neurotransmitter Uptake Inhibitors; Norepinephrine; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Structure-Activity Relationship | 2009 |
Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.
Topics: Animals; Antidepressive Agents; Disease Models, Animal; Dopamine; Drug Evaluation, Preclinical; Mice; Naphthalenes; Neurotransmitter Uptake Inhibitors; Norepinephrine; Serotonin | 2011 |
Synthesis and biological evaluation of novel 3,4-diaryl lactam derivatives as triple reuptake inhibitors.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Lactams; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Pyrrolidinones; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2013 |
Norepinephrine-stimulated cyclic AMP accumulation in brain slices in vitro after serotonin depletion or chronic administration of selective amine reuptake inhibitors.
Topics: Animals; Brain; Cyclic AMP; Desipramine; Fluoxetine; In Vitro Techniques; Male; Norepinephrine; p-Chloroamphetamine; Phenyl Ethers; Propylamines; Rats; Serotonin | 1977 |
Subsensitivity of the norepinephrine receptor-coupled adenylate cyclase system in brain: effects of nisoxetine versus fluoxetine.
Topics: Adenylyl Cyclases; Animals; Brain; Desipramine; Dihydroalprenolol; Fluoxetine; Male; Norepinephrine; Propylamines; Rats; Receptors, Adrenergic | 1979 |
Nisoxetine prevents the 6-hydroxydopamine induced decrease in post-decapitation convulsions.
Topics: Animals; Brain Stem; Cerebral Cortex; Decerebrate State; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Hydroxydopamines; Male; Norepinephrine; Phenyl Ethers; Propylamines; Rats; Seizures; Spinal Cord | 1977 |
dl-N-methyl-3-(o-methoxyphenoxy)-3-phenylpropylamine hydrochloride, Lilly 94939, a potent inhibitor for uptake of norepinephrine into rat brain synaptosomes and heart.
Topics: Animals; Biological Transport; Brain; Depression, Chemical; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Heart; Male; Myocardium; Norepinephrine; Phenyl Ethers; Propylamines; Rats; Synaptosomes | 1975 |
Effects of repeated administration of desipramine or electroconvulsive shock on norepinephrine uptake sites measured by [3H]nisoxetine autoradiography.
Topics: Animals; Autoradiography; Desipramine; Electroshock; Fluoxetine; Male; Norepinephrine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tritium | 1992 |
Characterization of the [3H]-desipramine binding site of the bovine adrenomedullary plasma membrane.
Topics: Adrenal Medulla; Animals; Binding Sites; Carrier Proteins; Cattle; Cell Membrane; Chlorides; Desipramine; Fluoxetine; Kinetics; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; PC12 Cells; Rats; Receptors, Drug; Receptors, Neurotransmitter; Sensitivity and Specificity; Sodium; Solubility; Symporters; Tritium | 1992 |
High- and low-affinity [3H]desipramine-binding sites in human postmortem brain tissue.
Topics: Adult; Aged; Aged, 80 and over; Animals; Brain; Carrier Proteins; Citalopram; Cricetinae; Desipramine; Female; Fluoxetine; Humans; Male; Middle Aged; Norepinephrine; Radioligand Assay; Receptors, Drug; Receptors, Neurotransmitter | 1990 |
Effect of monoamine uptake inhibitors on norepinephrine-stimulated phosphatidylinositol hydrolysis in rat cortex.
Topics: Animals; Cerebral Cortex; Cocaine; Desipramine; Fluoxetine; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Phosphatidylinositols; Prazosin; Rats; Receptors, Adrenergic, alpha | 1989 |
[3H]desipramine binding to rat brain tissue: binding to both noradrenaline uptake sites and sites not related to noradrenaline neurons.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Desipramine; Endopeptidases; Fluoxetine; Male; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium | 1989 |
Effect of chronic treatment with tricyclic antidepressants upon antinociception induced by intrathecal injection of morphine and monoamines.
Topics: Analgesia; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Drug Interactions; Fluoxetine; Male; Morphine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin; Time Factors | 1988 |
Some pharmacological actions of nisoxetine, a bicyclic inhibitor of noradrenaline uptake.
Topics: Animals; Bradykinin; Carbachol; Desipramine; Fluoxetine; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Propylamines; Rats; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Xylazine | 1985 |
Characterization of the inhibitory effect of some antidepressant drugs on the outward transport of norepinephrine in the ischemic myocardium.
Topics: Animals; Antidepressive Agents; Biological Transport, Active; Chromatography, High Pressure Liquid; Clonidine; Coronary Disease; Desipramine; Fluoxetine; Heart; Isomerism; Lidocaine; Male; Maprotiline; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains | 1988 |
Effects of norepinephrine and serotonin uptake inhibitors on the schedule-controlled behavior of the pigeon.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Columbidae; Conditioning, Operant; Desipramine; Doxepin; Fluoxetine; Iprindole; Male; Norepinephrine; Protriptyline; Reinforcement Schedule; Serotonin Antagonists | 1984 |
Effects of norepinephrine and 5-hydroxytryptamine reuptake inhibitors on electrically-induced spinal cord seizures in rats.
Topics: Animals; Benzofurans; Citalopram; Desipramine; Electric Stimulation; Female; Fluoxetine; Norepinephrine; Propylamines; Rats; Seizures; Serotonin Antagonists; Spinal Cord | 1980 |
Effects of acutely and chronically administered antidepressants on the clonidine-induced decrease in rat brain 3-methoxy-4-hydroxyphenylethylene-glycol sulphate content.
Topics: Animals; Antidepressive Agents; Brain; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; Desipramine; Fluoxetine; Glycols; Iprindole; Male; Methoxyhydroxyphenylglycol; Mianserin; Rats | 1981 |
Effects of monoamine reuptake inhibitors on cocaine self-administration in rats.
Topics: Animals; Biogenic Monoamines; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Injections, Intravenous; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 1995 |
Comparison of (R)-[3H]tomoxetine and (R/S)-[3H]nisoxetine binding in rat brain.
Topics: Animals; Atomoxetine Hydrochloride; Autoradiography; Binding Sites; Brain; Citalopram; Desipramine; Fluoxetine; Male; Norepinephrine; Propylamines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tritium | 1995 |
Monoamine uptake inhibitors alter cocaine pharmacokinetics.
Topics: Animals; Biotransformation; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Drug Interactions; Fluoxetine; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley | 1993 |
Effects of locally applied cocaine, lidocaine, and various uptake blockers on monoamine transmission in the ventral tegmental area of freely moving rats: a microdialysis study on monoamine interrelationships.
Topics: Animals; Biogenic Monoamines; Citalopram; Cocaine; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Lidocaine; Ligands; Male; Microdialysis; Movement; Norepinephrine; Piperazines; Rats; Serotonin; Tetrodotoxin; Ventral Tegmental Area | 1994 |
In vitro effects of cocaine, lidocaine and monoamine uptake inhibitors on lymphocyte proliferative responses.
Topics: Animals; B-Lymphocytes; Cells, Cultured; Cocaine; Desipramine; Fluoxetine; Lidocaine; Lymphocyte Activation; Male; Mitogens; Monoamine Oxidase Inhibitors; Nomifensine; Rats; Rats, Sprague-Dawley; Spleen; T-Lymphocytes | 1994 |
Cocaine: cardiovascular effects in relation to inhibition of peripheral neuronal monoamine uptake and central stimulation of the sympathoadrenal system.
Topics: Adrenal Medulla; Animals; Biological Transport; Blood Pressure; Catecholamines; Chlorisondamine; Cocaine; Desipramine; Fluoxetine; Heart Rate; Male; Norepinephrine; Oxidopamine; Peripheral Nervous System; Propanolamines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Time Factors | 1993 |
Localization of rat brain binding sites for [3H]tomoxetine, an enantiomerically pure ligand for norepinephrine reuptake sites.
Topics: Animals; Atomoxetine Hydrochloride; Binding Sites; Desipramine; Fluoxetine; Kinetics; Ligands; Male; Nerve Tissue Proteins; Norepinephrine; Piperazines; Propylamines; Prosencephalon; Rats; Rats, Sprague-Dawley | 1993 |
Nonexocytotic noradrenaline release and ventricular fibrillation in ischemic rat hearts.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Arrhythmia Agents; Carrier Proteins; Desipramine; Exocytosis; Fluoxetine; In Vitro Techniques; Male; Myocardial Ischemia; Norepinephrine; Rats; Rats, Wistar; Ventricular Fibrillation | 1995 |
Down-regulation of norepinephrine transporters on PC12 cells by transporter inhibitors.
Topics: Animals; Antidepressive Agents; Binding Sites; Carrier Proteins; Cell Count; Cell Survival; Desipramine; Down-Regulation; Fluoxetine; Kinetics; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; PC12 Cells; Rats; Symporters; Therapeutic Irrigation | 1997 |
Discriminative stimulus properties of cocaine: enhancement by monoamine reuptake blockers.
Topics: Animals; Cocaine; Desipramine; Discrimination Learning; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin; Ventral Tegmental Area | 1998 |
Anticonvulsant effect of enhancement of noradrenergic transmission in the superior colliculus in genetically epilepsy-prone rats (GEPRs): a microinjection study.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Anticonvulsants; Desipramine; Drug Interactions; Epilepsy; Female; Fluoxetine; Idazoxan; Methoxamine; Microinjections; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Superior Colliculi; Synaptic Transmission | 1998 |
Down-regulation of the human norepinephrine transporter in intact 293-hNET cells exposed to desipramine.
Topics: Adrenergic Uptake Inhibitors; Blotting, Western; Carrier Proteins; Cell Line; Desipramine; Embryo, Mammalian; Fluoxetine; Humans; Kidney; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; RNA, Messenger; Symporters | 1998 |
Voltammetric studies on mechanisms of dopamine efflux in the presence of substrates and cocaine from cells expressing human norepinephrine transporter.
Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Carrier Proteins; Cocaine; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Fluoxetine; Humans; Ionophores; Kinetics; LLC-PK1 Cells; Membrane Potentials; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Ouabain; Phenethylamines; Psychotropic Drugs; Swine; Symporters; Time Factors; Tyramine; Valinomycin; Veratridine | 1998 |
Elevation of extracellular cortical noradrenaline may contribute to the antidepressant activity of zotepine: an in vivo microdialysis study in freely moving rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Calcium; Desipramine; Dibenzothiepins; Extracellular Space; Fluoxetine; Frontal Lobe; Kinetics; Male; Microdialysis; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley | 1998 |
Desipramine treatment decreases 3H-nisoxetine binding and norepinephrine transporter mRNA in SK-N-SHSY5Y cells.
Topics: Adrenergic Uptake Inhibitors; Carrier Proteins; Desipramine; Fluoxetine; Humans; Neuroblastoma; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters; Tumor Cells, Cultured | 1999 |
Nicotinic acetylcholine receptor antagonistic activity of monoamine uptake blockers in rat hippocampal slices.
Topics: Animals; Culture Techniques; Desipramine; Electric Stimulation; Electrophysiology; Fluoxetine; Hippocampus; Male; Neurons; Neurotransmitter Uptake Inhibitors; Nicotinic Antagonists; Nomifensine; Norepinephrine; Rats; Rats, Wistar; Receptors, Nicotinic; Sodium Channels; Superior Cervical Ganglion; Tetrodotoxin | 1999 |
Activation and desensitization by cyclic antidepressant drugs of alpha2-autoreceptors, alpha2-heteroreceptors and 5-HT1A-autoreceptors regulating monamine synthesis in the rat brain in vivo.
Topics: 5-Hydroxytryptophan; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Autoreceptors; Brain; Carboxy-Lyases; Cerebral Cortex; Desipramine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Hippocampus; Male; Norepinephrine; Protriptyline; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors; Tryptophan; Tyrosine; Zimeldine | 1999 |
Noradrenergic lesion antagonizes desipramine-induced adaptation of NMDA receptors.
Topics: Adaptation, Physiological; Animals; Antidepressive Agents, Tricyclic; Benzylamines; Cerebral Cortex; Desipramine; Fluoxetine; Glycine; Kynurenic Acid; Male; Mice; Norepinephrine; Receptors, N-Methyl-D-Aspartate | 2000 |
Effects of chronic antidepressant treatments on 5-HT and NA transporters in rat brain: an autoradiographic study.
Topics: Animals; Antidepressive Agents; Autoradiography; Brain Chemistry; Carrier Proteins; Citalopram; Cyclohexanols; Desipramine; Fluoxetine; Gene Expression Regulation; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Stereotaxic Techniques; Symporters; Trimipramine; Venlafaxine Hydrochloride | 2001 |
Chamber-specific alterations of noradrenaline uptake (uptake(1)) in right ventricles of monocrotaline-treated rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Heart Failure; Heart Ventricles; Hypertrophy; In Vitro Techniques; Male; Membranes; Monocrotaline; Norepinephrine; Piperazines; Rats; Rats, Wistar; Tritium | 2000 |
Tyrosine residue 271 of the norepinephrine transporter is an important determinant of its pharmacology.
Topics: Amino Acid Substitution; Animals; Biological Transport; Chlorocebus aethiops; Cocaine; Codon; COS Cells; Desipramine; Dopamine; Fluoxetine; Humans; Kinetics; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Structure-Activity Relationship; Symporters; Transfection; Tyrosine | 2001 |
Pharmacological properties of the naturally occurring Ala(457)Pro variant of the human norepinephrine transporter.
Topics: Adrenergic Uptake Inhibitors; Amino Acid Substitution; Animals; Binding Sites; Cocaine; COS Cells; Desipramine; Dopamine Uptake Inhibitors; Fluoxetine; Green Fluorescent Proteins; Humans; Luminescent Proteins; Mutagenesis, Site-Directed; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Isoforms; Symporters; Transfection | 2002 |
Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter.
Topics: Amino Acid Substitution; Animals; Binding, Competitive; Cell Line; Cocaine; Conserved Sequence; COS Cells; Desipramine; Dopamine Agents; Female; Fluoxetine; Gene Expression; Glutamic Acid; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Ovary; Sequence Homology, Amino Acid; Sodium; Structure-Activity Relationship; Symporters; Transfection | 2002 |
The role of the conserved GXXXRXG motif in the expression and function of the human norepinephrine transporter.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arginine; Binding Sites; Cell Line; Cocaine; Conserved Sequence; Desipramine; Enzyme Inhibitors; Fluoxetine; Glycine; Humans; Mutagenesis, Site-Directed; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Sequence Alignment; Symporters; Vasoconstrictor Agents | 2002 |
A new norepinephrine transporter imaging agent for cardiac sympathetic nervous function imaging: radioiodinated (R)-N-methyl-3-(2-iodophenoxy)-3-phenylpropanamine.
Topics: Animals; Cells, Cultured; Desipramine; Fluoxetine; Heart; Heart Ventricles; Humans; Iodine Radioisotopes; Isotope Labeling; Male; Metabolic Clearance Rate; Myocardium; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Symporters; Tissue Distribution | 2003 |
Mechanism-based inhibition of CYP activities in rat liver by fluoxetine and structurally similar alkylamines.
Topics: Adrenergic Uptake Inhibitors; Amines; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P450 Family 2; Desipramine; Diffusion; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Heme; Hydroxylation; Inhibitory Concentration 50; Kinetics; Liver; Male; Microsomes, Liver; Models, Chemical; NADP; Nortriptyline; Oxygen; Protein Binding; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Steroid 16-alpha-Hydroxylase; Steroids; Time Factors | 2003 |
Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Amygdala; Animals; Antidepressive Agents, Tricyclic; Binding, Competitive; Desipramine; Electrochemistry; Excitatory Amino Acid Antagonists; Fluoxetine; Humans; Imipramine; In Vitro Techniques; Locus Coeruleus; Male; Microelectrodes; Norepinephrine Plasma Membrane Transport Proteins; Pyridines; Radioligand Assay; Rats; Receptors, Kainic Acid; Symporters; Time Factors | 2003 |
Regulation of the norepinephrine transporter by chronic administration of antidepressants.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Autoradiography; Brain; Cerebral Cortex; Desipramine; Fluoxetine; Hippocampus; In Situ Hybridization; Locus Coeruleus; Male; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Symporters | 2004 |
The persistent membrane retention of desipramine causes lasting inhibition of norepinephrine transporter function.
Topics: Adrenergic Uptake Inhibitors; Cell Line; Cell Membrane; Desipramine; Fluoxetine; Humans; Norepinephrine Plasma Membrane Transport Proteins; Symporters; Time Factors | 2004 |
Cocaine-induced modulation of long-term potentiation in the CA1 region of rat hippocampus.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Benzazepines; Cocaine; Desipramine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fluoxetine; Hippocampus; In Vitro Techniques; Lidocaine; Long-Term Potentiation; Neurotransmitter Uptake Inhibitors; Piperazines; Propranolol; Rats; Rats, Sprague-Dawley; Salicylamides; Tetrodotoxin | 2005 |
Evaluation of radioiodinated (2S,alphaS)-2-(alpha-(2-iodophenoxy)benzyl)morpholine as a radioligand for imaging of norepinephrine transporter in the heart.
Topics: Animals; Binding, Competitive; Desipramine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluoxetine; Heart; Iodine Radioisotopes; Isotope Labeling; Metabolic Clearance Rate; Morpholines; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Radioligand Assay; Radionuclide Imaging; Radiopharmaceuticals; Rats; Reboxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tissue Distribution | 2008 |
Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine.
Topics: alpha-Methyltyrosine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Binding, Competitive; Brain; Depressive Disorder; Desipramine; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Fluoxetine; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Stress, Psychological; Synaptic Transmission; Time | 2008 |
Mouse strain differences in immobility and sensitivity to fluvoxamine and desipramine in the forced swimming test: analysis of serotonin and noradrenaline transporter binding.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Motor Activity; Norepinephrine Plasma Membrane Transport Proteins; Serotonin Plasma Membrane Transport Proteins; Species Specificity; Swimming | 2008 |
Effects of anti-depressant treatments on FADD and p-FADD protein in rat brain cortex: enhanced anti-apoptotic p-FADD/FADD ratio after chronic desipramine and fluoxetine administration.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Apoptosis; Autoreceptors; Blotting, Western; Brain; CASP8 and FADD-Like Apoptosis Regulating Protein; Cerebral Cortex; Clorgyline; Desipramine; Electroshock; Excitatory Amino Acid Antagonists; Fas-Associated Death Domain Protein; Fluoxetine; Idazoxan; Indans; Ketamine; Male; Mianserin; Mirtazapine; Monoamine Oxidase Inhibitors; Norepinephrine Plasma Membrane Transport Proteins; Phenelzine; Phosphoproteins; Phosphorylation; Rats; RNA-Binding Proteins; Thiazoles | 2016 |