Page last updated: 2024-08-23

nimustine and lomustine

nimustine has been researched along with lomustine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's3 (15.79)18.2507
2000's5 (26.32)29.6817
2010's1 (5.26)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Akaike, Y; Arai, Y; Kawamori, M; Morikawa, T; Ozeki, M; Tsujihara, K1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Dombrowski, H; Drings, P; Hans, K; Harms, V; Havemann, K; Holle, R; Victor, N; Wolf, M1
Ishida, R; Takahashi, T; Utsumi, KR1
Kobayashi, T1
Moy, BC; Schein, PS; Tew, KD; Vu, VT1
Kamiya, S1
Bosanquet, AG1
Wakui, A1
Oguro, M; Takenaga, K; Yanagawa, T1
Kohda, K; Terashima, I1
Vuoristo, MS1
Alberto, P; Bacchi, M; Bernhard, J; Cavalli, F; Hürny, C; Joss, RA; Leyvraz, S; Ludwig, C; Senn, HJ; Stahel, R1
Weller, M; Winter, S1
Deininger, MH; Grote, E; Meyermann, R; Wickboldt, J1
Bardenheuer, W; Flasshove, M; Jansen, M; Moritz, T; Seeber, S; Sorg, UR1
Berrak, S; Koontz Webb, SE; Wolff, JE; Zhang, M1
Atta, J; Franz, K; Lemercier, S; Rieger, J; Steinbach, JP; Sulzbacher, A; Thiepold, AL1
Fujii, T; Ichimura, K; Kawauchi, D; Kobayashi, T; Kondo, A; Nakano, T; Narita, Y; Sasaki, N; Satomi, K; Takahashi, M; Tomiyama, A; Uchida, E; Wada, K; Yamamuro, S; Yoshino, A1

Reviews

2 review(s) available for nimustine and lomustine

ArticleYear
Stability of solutions of antineoplastic agents during preparation and storage for in vitro assays. General considerations, the nitrosoureas and alkylating agents.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Alkylation; Antineoplastic Agents; Carmustine; Chlorambucil; Colony-Forming Units Assay; Cyclophosphamide; Drug Storage; Hydrogen-Ion Concentration; Lomustine; Mathematics; Melphalan; Nimustine; Nitrosourea Compounds; Solutions; Temperature; Tumor Stem Cell Assay

1985
[Cancer chemotherapy with special reference to pharmacokinetics of nitrosoureas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:8

    Topics: Carmustine; Humans; Kinetics; Lomustine; Neoplasms; Nimustine; Nitrosourea Compounds; Semustine; Solubility; Streptozocin

1982

Trials

3 trial(s) available for nimustine and lomustine

ArticleYear
The prognostic value of response to the first cycle of chemotherapy in small cell lung cancer. Results of a multicenter German trial.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Lomustine; Lung Neoplasms; Male; Methotrexate; Nimustine; Nitrosourea Compounds; Peplomycin; Prognosis; Random Allocation; Vincristine; Vindesine

1987
Complete responses and survival after polychemotherapy plus interferon-alpha for patients with metastatic melanoma.
    Melanoma research, 1996, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Dacarbazine; Female; Humans; Immunotherapy; Interferon alpha-2; Interferon-alpha; Lomustine; Male; Melanoma; Middle Aged; Nimustine; Recombinant Proteins; Treatment Outcome; Vincristine

1996
Initial prognostic factors in small-cell lung cancer patients predicting quality of life during chemotherapy. Swiss Group for Clinical Cancer Research (SAKK).
    British journal of cancer, 1996, Volume: 74, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nimustine; Peplomycin; Prognosis; Quality of Life; Vincristine

1996

Other Studies

14 other study(ies) available for nimustine and lomustine

ArticleYear
A new class of nitrosoureas. 4. Synthesis and antitumor activity of disaccharide derivatives of 3,3-disubstituted 1-(2-chloroethyl)-1-nitrosoureas.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:4

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Leukemia L1210; Lomustine; Male; Mice; Nitrosourea Compounds

1982
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Sister-chromatid exchanges (SCEs), cell survival and mutation in HeLa s3 cells with different sensitivity to alkylating agents; evidence that SCE induction and cell survival or mutation induction are dissociable.
    Mutation research, 1989, Volume: 215, Issue:1

    Topics: Alkylating Agents; Cell Survival; HeLa Cells; Humans; Lomustine; Methylnitronitrosoguanidine; Mutation; Nimustine; Sister Chromatid Exchange; Structure-Activity Relationship

1989
[New developments in chemotherapy for experimental brain metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:3 Pt 2

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Daunorubicin; Doxorubicin; Floxuridine; Hydantoins; Leukemia, Myeloid; Liver Neoplasms, Experimental; Lomustine; Meningeal Neoplasms; Methotrexate; Neoplasm Transplantation; Nimustine; Nitrogen Mustard Compounds; Nitrosourea Compounds; Procarbazine; Rats

1985
Enhanced nitrosourea cytotoxicity in cell culture by sodium butyrate.
    Oncology, 1985, Volume: 42, Issue:5

    Topics: Butyrates; Butyric Acid; Cell Survival; Colony-Forming Units Assay; Drug Synergism; Female; HeLa Cells; Humans; Lomustine; Nimustine; Nitrogen Mustard Compounds; Nitrosourea Compounds; Phosphoramide Mustards; Streptozocin

1985
[Synthesis of antitumor nitrosourea derivatives and chemical studies of their mechanism of action].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1986, Issue:104

    Topics: Antineoplastic Agents; Bone Marrow; Carmustine; Humans; Lomustine; Nimustine; Nitroso Compounds; Nitrosourea Compounds

1986
[Antitumor activity of a new nitrosourea, MCNU, on a cellular morphological basis evaluated by a new in vitro antitumor sensitivity assay].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 1

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Leukemia L1210; Lomustine; Nimustine; Nitrosourea Compounds; Semustine; Tumor Stem Cell Assay

1984
Cytotoxicity of fluoroethylating agents is potentiated by O6-benzylguanine.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carmustine; Cell Survival; Drug Synergism; Guanine; HeLa Cells; Humans; Iodoacetamide; Lomustine; Nimustine

1996
Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells.
    European journal of pharmacology, 2000, Jun-16, Volume: 398, Issue:2

    Topics: Benzamides; Binding Sites; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; G2 Phase; Glioma; Humans; Lomustine; Methylnitrosourea; Mitosis; Nimustine; Nitrosourea Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tumor Cells, Cultured

2000
Distinct radiochemotherapy protocols differentially influence cellular proliferation and expression of p53 and Bcl-2 in glioblastoma multiforme relapses in vivo.
    Journal of neuro-oncology, 2000, Volume: 48, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers; Brain Neoplasms; Cell Division; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes; Genes, bcl-2; Glioblastoma; GTP-Binding Proteins; Humans; Ki-67 Antigen; Life Tables; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Nimustine; Protein Glutamine gamma Glutamyltransferase 2; Proto-Oncogene Proteins c-bcl-2; Radiotherapy, Adjuvant; Survival Analysis; Teniposide; Transglutaminases; Tumor Suppressor Protein p53

2000
Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.
    European journal of haematology, 2001, Volume: 67, Issue:1

    Topics: Alkylating Agents; Alkylation; Animals; Carmustine; Cells, Cultured; Colony-Forming Units Assay; Dacarbazine; DNA Damage; DNA, Complementary; Drug Resistance; Genetic Vectors; Hematopoietic Stem Cells; Humans; Lomustine; Mice; Moloney murine leukemia virus; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Recombinant Fusion Proteins; Retroviridae; Sarcoma Viruses, Murine; Spleen Focus-Forming Viruses; Temozolomide; Terminal Repeat Sequences; Transfection

2001
Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Cohort Studies; Data Interpretation, Statistical; Databases, Factual; Female; Glioblastoma; Glioma; Humans; Lomustine; Male; Nimustine; Nitrosourea Compounds; Reproducibility of Results; Selection Bias; Survival Analysis; Treatment Outcome

2008
Prophylactic use of pegfilgrastim in patients treated with a nitrosourea and teniposide for recurrent glioma.
    Pharmacotherapy, 2014, Volume: 34, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Communicable Diseases; Disease-Free Survival; Female; Filgrastim; Germany; Glioma; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Severity of Illness Index; Survival Rate; Teniposide

2014
Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance.
    Cancer science, 2021, Volume: 112, Issue:11

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Glioblastoma; Histones; Humans; Injections, Intraperitoneal; Lomustine; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; Nimustine; Salvage Therapy; Temozolomide; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2021