nimesulide and thromboxane b2

nimesulide has been researched along with thromboxane b2 in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (40.00)18.2507
2000's9 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harada, Y; Hatanaka, K; Katori, M; Kawamura, M; Majima, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Taketani, Y; Yamamoto, K; Yamamoto, S1
Famaey, JP1
Harada, Y; Hatanaka, K; Kawamura, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Yang, Q1
Connor, SO; Cullen, L; Fitzgerald, DJ; Kelly, L1
Giuliano, F; Warner, TD1
Chiang, N; Clària, J; Gaya, J; Pueyo, G; Romano, M; Serhan, CN; Titos, E1
Belton, O; Byrne, D; Fitzgerald, DJ; Kearney, D; Leahy, A1
Ciabattoni, G; Collura, M; Davì, G; Ganci, A; Iapichino, L; Maclouf, J; Pardo, F; Patrono, C; Romagnoli, R1
Ballerio, R; Bianchib, M; Buccellati, C; Sala, A1
Barry, M; Bjarnason, I; Fitzgerald, DJ; Gudjonsson, H; Kay, E; Murray, FE; Oddsson, E; Price, AB; Shah, AA; Sigthorsson, G; Thjodleifsson, B1
FitzGerald, GA; Li, H; Praticò, D; Tillmann, C; Zhang, ZB1
Kömhoff, M; Nüsing, RM; Peters, M; Reinalter, SC; Seyberth, HW1
Chavatte, P; Gressier, B; Luyckx, M; Park, CH; Siomboing, X; Yous, S1
Del Soldato, P; Gray, PA; Mitchell, JA; Parikh, A; Scadding, GK; Vojnovic, I; Warner, TD1
Kankaanranta, H; Kerola, M; Kosonen, O; Moilanen, E; Sarna, S; Vuolteenaho, K1

Reviews

1 review(s) available for nimesulide and thromboxane b2

ArticleYear
In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2

1997

Trials

5 trial(s) available for nimesulide and thromboxane b2

ArticleYear
Selective cyclooxygenase-2 inhibition by nimesulide in man.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides; Thromboxane B2

1998
Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis.
    Circulation, 2000, Aug-22, Volume: 102, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Epoprostenol; F2-Isoprostanes; Female; Humans; Isoenzymes; Macrophages; Male; Membrane Proteins; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane A2; Thromboxane B2

2000
Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen.
    Gut, 2001, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Aged; Biomarkers; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Gastric Mucosa; Gastrointestinal Diseases; Humans; Intestinal Mucosa; Male; Middle Aged; Naproxen; Permeability; Platelet Aggregation; Prostaglandins E; Sulfonamides; Thromboxane B2

2001
Pathogenetic role of cyclooxygenase-2 in hyperprostaglandin E syndrome/antenatal Bartter syndrome: therapeutic use of the cyclooxygenase-2 inhibitor nimesulide.
    Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Bartter Syndrome; Blood Platelets; Child; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Indomethacin; Isoenzymes; Kidney; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Sulfonamides; Thromboxane B2

2001
Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Ibuprofen; Male; Nabumetone; Sulfonamides; Thromboxane B2

2009

Other Studies

9 other study(ies) available for nimesulide and thromboxane b2

ArticleYear
Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy.
    Prostaglandins, 1996, Volume: 51, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Azo Compounds; Blotting, Western; Carrageenan; Cell Count; Cells, Cultured; Coloring Agents; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Excipients; Inflammation; Isoenzymes; Leukocytes; Male; Nitrobenzenes; Pleura; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Thromboxane B2; Trypan Blue

1996
Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat.
    Prostaglandins & other lipid mediators, 1998, Volume: 55, Issue:5-6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gastric Juice; Indomethacin; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Pleurisy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Thromboxane B2

1998
Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs.
    British journal of pharmacology, 1999, Volume: 126, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Carcinoma; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salicylates; Substrate Specificity; Sulfonamides; Sulindac; Thromboxane B2; Tumor Cells, Cultured

1999
Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Animals; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Isoenzymes; Lipoxins; Liver; Male; Membrane Proteins; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Thromboxane B2

1999
In vivo lipid peroxidation and platelet activation in cystic fibrosis.
    American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:4 Pt 1

    Topics: Adolescent; Adult; Child; Cyclooxygenase Inhibitors; Cystic Fibrosis; Dinoprost; F2-Isoprostanes; Female; Genotype; Humans; Ibuprofen; Lipid Peroxidation; Lung; Male; Platelet Activation; Sulfonamides; Thromboxane B2; Vitamin E

2000
Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases.
    European journal of pain (London, England), 2000, Volume: 4, Issue:4

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; In Vitro Techniques; Isoenzymes; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2; Tramadol

2000
Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Mar-13, Volume: 98, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Coronary Artery Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epoprostenol; Female; Indomethacin; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Receptors, LDL; Sulfonamides; Thromboxane B2

2001
Investigations of new lead structures for the design of novel cyclooxygenase-2 inhibitors.
    European journal of medicinal chemistry, 2002, Volume: 37, Issue:6

    Topics: Cell Survival; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Humans; In Vitro Techniques; Indicators and Reagents; Isoenzymes; Membrane Proteins; Models, Molecular; Molecular Conformation; Monocytes; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship; Sulfonamides; Thromboxane B2

2002
Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Benzene Derivatives; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Furans; Humans; Indomethacin; Ionophores; Isoenzymes; Leukotrienes; Lipopolysaccharides; Lipoxygenase; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2

2002