nimesulide and rofecoxib

nimesulide has been researched along with rofecoxib in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's27 (84.38)29.6817
2010's5 (15.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Backlund, A; Bohlin, L; Gottfries, J; Larsson, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Hawkey, CJ; Jackson, LM1
Mejza, F; Nizankowska, E1
Jain, NK; Kulkarni, SK; Singh, A1
Jain, NK; Kulkarni, SK; Patil, CS; Singh, A1
Bianchi, M; Broggini, M2
Devière, J1
Bhatia, S; Seedher, N1
Bracco, P; Calabrese, N; Coscia, D; Debernardi, C; Pasqualicchio, F; Pasqualini, D1
Bavbek, S; Celik, G; Misirligil, Z; Mungan, D; Ozer, F1
Villa, G1
Benoit, V; de Leval, X; Dogné, JM; Frederich, M; Julémont, F; Pirotte, B1
Meena, S; Nagaraju, D; Rao, AR; Rao, RN1
de Champlain, J; Laplante, MA; Wu, R1
Caron, G; Ermondi, G; Lawrence, R; Longo, D1
Asero, R2
Meena, S; Nageswara Rao, R; Raghuram Rao, A1
Beata, RN; Ryszard, M; Stanisław, S; Wojciech, F1
Dhir, A; Kulkarni, SK; Naidu, PS1
Alpert, E; Cohen, G; Gruzman, A; Lardi-Studler, B; Reich, R; Sasson, S1
Fraunfelder, FW; Mehelas, TJ; Solomon, J1
Bishnoi, M; Kulkarni, SK; Kumar, A; Patil, CS2
Arana, A; Castellsague, J; Perez-Gutthann, S; Sanchez-Matienzo, D1
Conforti, A; Leone, R; Montanaro, N; Moretti, U; Motola, D; Vaccheri, A; Vargiu, A; Velo, G1
Kalonia, H; Kumar, A; Kumar, P; Nehru, B1
Kumar, A; Kumar, P; Kumari, B1
Gołab, J; Jakubowska-Mućka, A; Lasek, W; Sieńko, J; Switaj, T1

Reviews

5 review(s) available for nimesulide and rofecoxib

ArticleYear
COX-2 selective nonsteroidal anti-Inflammatory drugs: do they really offer any advantages?
    Drugs, 2000, Volume: 59, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Etodolac; Humans; Lactones; Meloxicam; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles

2000
[Selective cyclooxygenase 2 inhibitors (COX-2)].
    Postepy higieny i medycyny doswiadczalnej, 2001, Volume: 55, Issue:2

    Topics: Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Inflammation; Isoenzymes; Lactones; Meloxicam; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles

2001
Do selective cyclo-oxygenase inhibitors eliminate the adverse events associated with nonsteroidal anti-inflammatory drug therapy?
    European journal of gastroenterology & hepatology, 2002, Volume: 14 Suppl 1

    Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Humans; Lactones; Meloxicam; Neoplasms; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles

2002
First and second generations of COX-2 selective inhibitors.
    Mini reviews in medicinal chemistry, 2004, Volume: 4, Issue:6

    Topics: Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etoricoxib; Gastrointestinal Diseases; Humans; Isoenzymes; Isoxazoles; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyridines; Sulfonamides; Sulfones

2004
An overview of the recent developments in analytical methodologies for determination of COX-2 inhibitors in bulk drugs, pharmaceuticals and biological matrices.
    Journal of pharmaceutical and biomedical analysis, 2005, Sep-15, Volume: 39, Issue:3-4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Industry; Etodolac; Etoricoxib; Lactones; Models, Chemical; Pyrazoles; Pyridines; Spectrophotometry; Sulfonamides; Sulfones; Ultraviolet Rays

2005

Trials

6 trial(s) available for nimesulide and rofecoxib

ArticleYear
Anti-hyperalgesic effects of nimesulide: studies in rats and humans.
    International journal of clinical practice. Supplement, 2002, Issue:128

    Topics: Aged; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Diclofenac; Double-Blind Method; Female; Humans; Hyperalgesia; Lactones; Male; Middle Aged; Models, Animal; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones

2002
A randomised, double-blind, clinical trial comparing the efficacy of nimesulide, celecoxib and rofecoxib in osteoarthritis of the knee.
    Drugs, 2003, Volume: 63 Suppl 1

    Topics: Adult; Aged; Analysis of Variance; Celecoxib; Double-Blind Method; Female; Humans; Knee; Lactones; Male; Middle Aged; Osteoarthritis; Osteoarthritis, Knee; Pain; Pain Measurement; Pyrazoles; Sulfonamides; Sulfones; Time Factors

2003
Efficacy of rofecoxib and nimesulide in controlling postextraction pain in oral surgery: a randomised comparative study.
    Current medical research and opinion, 2004, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Lactones; Male; Middle Aged; Molar, Third; Pain, Postoperative; Sulfonamides; Sulfones; Tooth Extraction; Tooth, Impacted

2004
Safety of selective COX-2 inhibitors in aspirin/nonsteroidal anti-inflammatory drug-intolerant patients: comparison of nimesulide, meloxicam, and rofecoxib.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2004, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Female; Humans; Immunologic Tests; Lactones; Male; Meloxicam; Middle Aged; Single-Blind Method; Sulfonamides; Sulfones; Thiazines; Thiazoles; Treatment Outcome; Urticaria

2004
Oral aspirin challenges in patients with a history of intolerance to single non-steroidal anti-inflammatory drugs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:6

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Cyclooxygenase Inhibitors; Drug Evaluation; Female; Humans; Lactones; Male; Middle Aged; ortho-Aminobenzoates; Recurrence; Single-Blind Method; Sulfonamides; Sulfones; Tramadol; Urticaria

2005
Use of ketoprofen oral challenges to detect cross-reactors among patients with a history of aspirin-induced urticaria.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross Reactions; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Female; Humans; Ketoprofen; Lactones; Male; Middle Aged; Placebos; Sulfonamides; Sulfones; Tramadol; Urticaria

2006

Other Studies

21 other study(ies) available for nimesulide and rofecoxib

ArticleYear
Expanding the ChemGPS chemical space with natural products.
    Journal of natural products, 2005, Volume: 68, Issue:7

    Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship

2005
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Lipopolysaccharide-mediated immobility in mice: reversal by cyclooxygenase enzyme inhibitors.
    Methods and findings in experimental and clinical pharmacology, 2001, Volume: 23, Issue:8

    Topics: Animals; Antidepressive Agents, Tricyclic; Cyclooxygenase Inhibitors; Desipramine; Enterotoxins; Female; Fluoxetine; Lactones; Lipopolysaccharides; Male; Mice; Motor Activity; Naproxen; Reserpine; Selective Serotonin Reuptake Inhibitors; Sulfonamides; Sulfones; Swimming

2001
Modulatory role of cyclooxygenase inhibitors in aging- and scopolamine or lipopolysaccharide-induced cognitive dysfunction in mice.
    Behavioural brain research, 2002, Jul-18, Volume: 133, Issue:2

    Topics: Aging; Animals; Anxiety; Avoidance Learning; Cognition Disorders; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Gastrointestinal Diseases; Isoenzymes; Lactones; Lipopolysaccharides; Male; Membrane Proteins; Mice; Motor Activity; Muscarinic Antagonists; Naproxen; Postural Balance; Prostaglandin-Endoperoxide Synthases; Scopolamine; Sulfonamides; Sulfones

2002
Solubility enhancement of Cox-2 inhibitors using various solvent systems.
    AAPS PharmSciTech, 2003, Volume: 4, Issue:3

    Topics: Celecoxib; Chemistry, Pharmaceutical; Cyclooxygenase 2; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isoenzymes; Lactones; Meloxicam; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Solubility; Solvents; Sulfonamides; Sulfones; Thiazines; Thiazoles

2003
Comment on efficacy of rofecoxib and nimesulide in controlling post-extraction pain in oral surgery: a randomised comparative study.
    Current medical research and opinion, 2004, Volume: 20, Issue:4

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans; Lactones; Pain, Postoperative; Randomized Controlled Trials as Topic; Sulfonamides; Sulfones; Tooth Extraction

2004
Development and validation of a reversed-phase liquid chromatographic method for separation and simultaneous determination of COX-2 inhibitors in pharmaceuticals and its application to biological fluids.
    Biomedical chromatography : BMC, 2005, Volume: 19, Issue:5

    Topics: Butanones; Celecoxib; Chromatography, Liquid; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Lactones; Nabumetone; Pyrazoles; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Sulfones

2005
Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:6

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiomegaly; Cells, Cultured; Cyclooxygenase Inhibitors; Hypertension; Lactones; Male; Myocardium; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones

2005
Docking studies on NSAID/COX-2 isozyme complexes using contact statistics analysis.
    Journal of computer-aided molecular design, 2004, Volume: 18, Issue:11

    Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Flurbiprofen; Humans; Isoenzymes; Lactones; Membrane Proteins; Models, Molecular; Models, Statistical; Molecular Conformation; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyrazoles; Sulfonamides; Sulfones

2004
The influence of anti-inflammatory drugs on the proliferation of fibroblast derived from nasal polyps.
    Auris, nasus, larynx, 2005, Volume: 32, Issue:3

    Topics: Anti-Inflammatory Agents; Budesonide; Cell Proliferation; Cells, Cultured; Fibroblasts; Humans; Ibuprofen; Lactones; Nasal Polyps; Sulfonamides; Sulfones

2005
Protective effect of cyclooxygenase-2 (COX-2) inhibitors but not non-selective cyclooxygenase (COX)-inhibitors on ethanol withdrawal-induced behavioural changes.
    Addiction biology, 2005, Volume: 10, Issue:4

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Behavior, Animal; Brain; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Injections, Intraperitoneal; Lactones; Male; Mice; Naproxen; Neuroprotective Agents; Sulfonamides; Sulfones

2005
Cyclooxygenase-2 (PTGS2) inhibitors augment the rate of hexose transport in L6 myotubes in an insulin- and AMPKalpha-independent manner.
    Diabetologia, 2006, Volume: 49, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Biological Transport; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Enzyme Activation; Hexoses; Insulin; Lactones; Male; Mice; Multienzyme Complexes; Muscle Fibers, Skeletal; Muscle, Skeletal; Niflumic Acid; Protein Serine-Threonine Kinases; Rats; Sulfonamides; Sulfones

2006
Ocular adverse effects associated with cyclooxygenase-2 inhibitors.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2006, Volume: 124, Issue:2

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Celecoxib; Conjunctivitis; Cyclooxygenase 2 Inhibitors; Etodolac; Humans; Isoxazoles; Lactones; Middle Aged; Pyrazoles; Sulfonamides; Sulfones; Vision Disorders

2006
Potentiation of antinociceptive effect of NSAIDs by a specific lipooxygenase inhibitor, acetyl 11-keto-beta boswellic acid.
    Indian journal of experimental biology, 2006, Volume: 44, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Lactones; Lipoxygenase Inhibitors; Mice; Naproxen; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Sulfones; Triterpenes

2006
Hepatic disorders in patients treated with COX-2 selective inhibitors or nonselective NSAIDs: a case/noncase analysis of spontaneous reports.
    Clinical therapeutics, 2006, Volume: 28, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Bromobenzenes; Celecoxib; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2 Inhibitors; Humans; Lactones; Odds Ratio; Pyrazoles; Safety; Sulfonamides; Sulfones; Sulindac

2006
Co-administration of acetyl-11-keto-beta-boswellic acid, a specific 5-lipoxygenase inhibitor, potentiates the protective effect of COX-2 inhibitors in kainic acid-induced neurotoxicity in mice.
    Pharmacology, 2007, Volume: 79, Issue:1

    Topics: Administration, Oral; Animals; Antinematodal Agents; Brain; Catalase; Cyclooxygenase 2 Inhibitors; Drug Synergism; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Glutathione; Indomethacin; Injections, Intraperitoneal; Kainic Acid; Lactones; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred Strains; Nitric Oxide; Peroxidase; Sulfonamides; Sulfones; Triterpenes

2007
Influence of regulatory measures on the rate of spontaneous adverse drug reaction reporting in Italy.
    Drug safety, 2008, Volume: 31, Issue:7

    Topics: Adverse Drug Reaction Reporting Systems; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Cough; Cyclooxygenase 2 Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Italy; Lactones; Liver; Rhabdomyolysis; Sulfonamides; Sulfones

2008
Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats.
    Neurotoxicology, 2010, Volume: 31, Issue:2

    Topics: Animals; Ataxia; Body Weight; Cell Survival; Corpus Striatum; Cyclooxygenase 2 Inhibitors; Lactones; Male; Microinjections; Mitochondria; Mitochondrial Diseases; Neurotoxicity Syndromes; Oxidative Stress; Quinolinic Acid; Rats; Rats, Wistar; Sulfonamides; Sulfones

2010
Protective effects of selective and non-selective cyclooxygenase inhibitors in an animal model of chronic stress.
    Neuroscience bulletin, 2010, Volume: 26, Issue:1

    Topics: Animals; Anxiety; Catalase; Chronic Disease; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Glutathione; Isoxazoles; Lactones; Lipid Peroxidation; Male; Meloxicam; Memory; Mice; Motor Activity; Naproxen; Nitrites; Random Allocation; Stress, Psychological; Sulfonamides; Sulfones; Thiazines; Thiazoles

2010
[Antitumor effects of sulindac in ovarian cell cultures].
    Ginekologia polska, 2011, Volume: 82, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Cell Cycle; Cell Size; Cell Survival; Colorimetry; Female; Humans; Lactones; Ovarian Neoplasms; Sulfonamides; Sulfones; Sulindac; Tumor Cells, Cultured

2011