nimesulide and piroxicam

nimesulide has been researched along with piroxicam in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	12 (34.29)	18.2507
2000's	11 (31.43)	29.6817
2010's	12 (34.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Churchill, L; Coutts, SJ; Cywin, CL; David, E; Engel, W; Graham, AG; Grob, PM; Hoermann, M; Kelly, TA; Lazer, ES; McNeil, DW; Meier, H; Meng, Z; Miao, CK; Potocki, I; Snow, RJ; Sorcek, R; Trummlitz, G; Tschantz, MA; Wong, HC	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Sansano, S; Wiesenberg-Böttcher, I; Zimmerli, W	1
Dreiser, RL; Riebenfeld, D	1
Awor, L; Gupta, SK; Joshi, S; Prakash, J; Sengupta, S; Velpandian, T	1
Alam, CA; Brown, JR; Colville-Nash, PR; Freemantle, CN; Papworth, JL; Seed, MP; Somerville, KW; Willoughby, DA	1
Gilroy, DW; Tomlinson, A; Willoughby, DA	1
Gilroy, DW; Greenslade, K; Seed, MP; Tomlinson, A; Willoughby, DA	1
Gupta, SK; Kabir, SR; Sengupta, S; Velpandian, T	1
Fanti, L; Foppa, L; Guslandi, M; Sorghi, M	1
Bracht, A; Ishii-Iwamoto, EL; Kelmer-Bracht, AM; Lopez, CH; Sampaio, E; Yamamoto, NS	1
Dhaon, BK; Gulati, P; Gupta, U; Roy, V; Sharma, S; Singh, NP	1
Dunn, AJ; Swiergiel, AH	1
Gulati, P; Gupta, V; Rastogi, S; Rohtagi, D; Sharma, S	1
de Zentella, PM; Pimentel, L; Piña, E; Piña-Zentella, G; Vázquez-Meza, H	1
Coceani, N; Grassi, M; Magarotto, L	1
Alderborn, G; Chopra, R; Newton, JM; Podczeck, F	1
Kalgutkar, AS; Kiefer, JR; Kozak, KR; Kurumbail, RG; Marnett, LJ; Pawlitz, JL; Prusakiewicz, JJ; Rowlinson, SW; Stallings, WC	1
Fujimoto, K; Hirao, Y; Ohnishi, S; Ohta, M; Okajima, E; Ozono, S; Tanaka, M; Tani, M; Uemura, H	1
Dubois, J; Gelbcke, M; Neve, J; Van Antwerpen, P	1
Agundis, C; Pardo, JP; Pereyra, MA; Piña, E; Vázquez-Meza, H; Villalobos-Molina, R; Zentella de Piña, M	1
Dastis, SN; Geubel, AP; Lerut, J; Rahier, J	1
Drozdov, VN; Tkachenko, EV; Trubitsyna, IE; Varvanina, GG	1
Efimov, MA; Koval'chuk, VV	1
Amidon, GE; Amidon, GL; Gao, P; Mudie, DM; Ping, H; Shi, Y	1
Lands, LC; Stanojevic, S	1
Brandao, MAF; de Oliveira Ferreira, A; Pelisson E Silva, TCC; Pereira, RO; Polonini, HC; Raposo, NRB	1

Reviews

2 review(s) available for nimesulide and piroxicam

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Oral non-steroidal anti-inflammatory drug therapy for lung disease in cystic fibrosis. The Cochrane database of systematic reviews, 2013, Jun-13, Issue:6 Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Clarithromycin; Cystic Fibrosis; Humans; Ibuprofen; Piroxicam; Randomized Controlled Trials as Topic; Sulfonamides	2013

Trials

4 trial(s) available for nimesulide and piroxicam

Article	Year
Nimesulide in the treatment of osteoarthritis. Double-blind studies in comparison with piroxicam, ketoprofen and placebo. Drugs, 1993, Volume: 46 Suppl 1 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ketoprofen; Male; Middle Aged; Osteoarthritis; Piroxicam; Sulfonamides	1993
Analgesic efficacy and pharmacokinetics of topical nimesulide gel in healthy human volunteers: double-blind comparison with piroxicam, diclofenac and placebo. European journal of clinical pharmacology, 1998, Volume: 54, Issue:7 Topics: Administration, Topical; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Male; Ointments; Piroxicam; Sulfonamides	1998
Comparative efficacy and tolerability of nimesulide and piroxicam in osteoarthritis with specific reference to chondroprotection: a double blind randomised study. Journal of the Indian Medical Association, 1999, Volume: 97, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Osteoarthritis, Knee; Piroxicam; Severity of Illness Index; Sulfonamides; Treatment Outcome	1999
Comparative efficacy and safety of nimesulide versus piroxicam in osteoarthritis with special reference to chondroprotection. American journal of therapeutics, 1999, Volume: 6, Issue:4 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Osteoarthritis; Piroxicam; Sulfonamides	1999

Other Studies

29 other study(ies) available for nimesulide and piroxicam

Article	Year
Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. Journal of medicinal chemistry, 1997, Mar-14, Volume: 40, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Magnetic Resonance Spectroscopy; Meloxicam; Membrane Proteins; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Thiazines; Thiazoles	1997
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Influence of the anti-inflammatory compound flosulide on granulocyte function. Biochemical pharmacology, 1991, Oct-24, Volume: 42, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemotaxis; Ibuprofen; Indans; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piroxicam; Sulfonamides; Superoxides	1991
Anti-inflammatory activity of topical nimesulide gel in various experimental models. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:12 Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Diclofenac; Disease Models, Animal; Edema; Female; Gels; Male; Piroxicam; Rats; Rats, Wistar; Sulfonamides	1996
Apoptosis induction and inhibition of colon-26 tumour growth and angiogenesis: findings on COX-1 and COX-2 inhibitors in vitro & in vivo and topical diclofenac in hyaluronan. Advances in experimental medicine and biology, 1997, Volume: 433 Topics: Administration, Topical; Animals; Apoptosis; Aspirin; Cell Division; Cell Survival; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Carriers; Female; Hyaluronic Acid; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred BALB C; Necrosis; Neovascularization, Pathologic; Piroxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides	1997
Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Piroxicam; Pleural Effusion; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides	1998
The effects of cyclooxygenase 2 inhibitors on cartilage erosion and bone loss in a model of Mycobacterium tuberculosis-induced monoarticular arthritis in the rat. Inflammation, 1998, Volume: 22, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Bone and Bones; Cartilage, Articular; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Isoenzymes; Male; Mycobacterium tuberculosis; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides	1998
Nonsteroidal anti-inflammatory drugs and gastric mucosal blood flow. Journal of clinical gastroenterology, 1999, Volume: 28, Issue:3 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Blood Flow Velocity; Diclofenac; Endoscopy, Digestive System; Female; Follow-Up Studies; Gastric Mucosa; Humans; Laser-Doppler Flowmetry; Male; Middle Aged; Piroxicam; Stomach Ulcer; Sulfonamides	1999
The action of flufenamic acid and other nonsteroidal anti-inflammatories on sulfate transport in the isolated perfused rat liver. General pharmacology, 1999, Volume: 32, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Dose-Response Relationship, Drug; Flufenamic Acid; In Vitro Techniques; Liver; Male; Mefenamic Acid; Naproxen; Niflumic Acid; Perfusion; Piroxicam; Rats; Rats, Wistar; Sulfates; Sulfonamides; Sulfur Radioisotopes; Time Factors	1999
The role of cyclooxygenases in endotoxin- and interleukin-1-induced hypophagia. Brain, behavior, and immunity, 2000, Volume: 14, Issue:3 Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Drinking; Endotoxins; Feeding and Eating Disorders; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Lipopolysaccharides; Male; Mice; Milk; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Sialoglycoproteins; Sulfonamides	2000
Non-steroidal anti-inflammatory drugs inhibit epinephrine- and cAMP-mediated lipolysis in isolated rat adipocytes. The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:4 Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bucladesine; Dihydroalprenolol; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Ethanol; Glycerol; Guinea Pigs; Lipolysis; Male; Naproxen; Piroxicam; Rats; Rats, Wistar; Sulfonamides; Thiobarbituric Acid Reactive Substances; Triglycerides	2002
Modelling partitioning of sparingly soluble drugs in a two-phase liquid system. International journal of pharmaceutics, 2002, Jun-04, Volume: 239, Issue:1-2 Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Pharmaceutical Preparations; Piroxicam; Solubility; Solvents; Sulfonamides	2002
The influence of pellet shape and surface properties on the drug release from uncoated and coated pellets. International journal of pharmaceutics, 2002, Jun-04, Volume: 239, Issue:1-2 Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Pharmaceutical Preparations; Piroxicam; Solubility; Solvents; Sulfonamides	2002
A novel mechanism of cyclooxygenase-2 inhibition involving interactions with Ser-530 and Tyr-385. The Journal of biological chemistry, 2003, Nov-14, Volume: 278, Issue:46 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arginine; Binding, Competitive; Cell Line; Crystallography, X-Ray; Cyclooxygenase 2; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Insecta; Isoenzymes; Mice; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Piroxicam; Prostaglandin-Endoperoxide Synthases; Protein Binding; Serine; Sulfonamides; Time Factors; Tyrosine	2003
Expression of cyclooxygenase-2 in primary superficial bladder cancer tissue may predict risk of its recurrence after complete transurethral resection. Aktuelle Urologie, 2003, Volume: 34, Issue:4 Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Female; Humans; Immunohistochemistry; Isoenzymes; Male; Membrane Proteins; Middle Aged; Neoplasm Recurrence, Local; Piroxicam; Prostaglandin-Endoperoxide Synthases; Rats; Risk Factors; Sulfonamides; Urinary Bladder Neoplasms	2003
The reactions of oxicam and sulfoanilide non steroidal anti-inflammatory drugs with hypochlorous acid: determination of the rate constants with an assay based on the competition with para-aminobenzoic acid chlorination and identification of some oxidation Free radical research, 2004, Volume: 38, Issue:3 Topics: 4-Aminobenzoic Acid; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Hypochlorous Acid; Kinetics; Linear Models; Meloxicam; Molecular Structure; Oxidation-Reduction; Piroxicam; Sulfonamides; Thiazines; Thiazoles	2004
Inhibition of cAMP-dependent protein kinase A: a novel cyclo-oxygenase-independent effect of non-steroidal anti-inflammatory drugs in adipocytes. Autonomic & autacoid pharmacology, 2007, Volume: 27, Issue:2 Topics: Adipocytes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Male; Myocardium; Naproxen; Piroxicam; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Rats; Rats, Wistar; Sterol Esterase; Sulfonamides	2007
Liver transplantation for nonsteroidal anti-inflammatory drug-induced liver failure: nimesulide as the first implicated compound. European journal of gastroenterology & hepatology, 2007, Volume: 19, Issue:11 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Failure, Acute; Liver Transplantation; Middle Aged; Piroxicam; Pyrazoles; Sulfonamides	2007
[Experimental NSAID-associated gastric mucosa injuries]. Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2008, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Female; Gastric Mucosa; Ligation; Male; Piroxicam; Rats; Stomach Ulcer; Sulfonamides	2008
[Efficacy and tolerability of short courses of nonsteroid anti-inflammatory drugs in the treatment of dorsalgia: results of the comparative study]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2010, Volume: 110, Issue:1 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Outpatients; Pain Measurement; Piroxicam; Sulfonamides; Treatment Outcome	2010
Mechanistic analysis of solute transport in an in vitro physiological two-phase dissolution apparatus. Biopharmaceutics & drug disposition, 2012, Volume: 33, Issue:7 Topics: Absorption; Biopharmaceutics; Drug Discovery; Drugs, Investigational; Humans; Ibuprofen; Kinetics; Models, Biological; Models, Chemical; Molecular Structure; Piroxicam; Solubility; Solutions; Sulfonamides	2012
Ex vivo Skin Permeation Evaluation of An Innovative Transdermal Vehicle Using Nimesulide and Piroxicam as Model Drugs. Current drug delivery, 2017, Volume: 14, Issue:4 Topics: Administration, Cutaneous; Drug Delivery Systems; Humans; In Vitro Techniques; Permeability; Piroxicam; Skin; Skin Absorption; Sulfonamides	2017