nimesulide and mocetinostat

nimesulide has been researched along with mocetinostat in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (16.67)18.2507
2000's10 (55.56)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ballestrero, A; Dallegri, F; Ferrando, F; Ottonello, L; Patrone, F; Sacchetti, C1
Dallegri, F; Dapino, P; Gatti, F; Guidi, G; Montagnani, G; Ottonello, L; Pastorino, G1
Dallegri, F; Dapino, P; Ottonello, L1
Cohen, P; Karmeli, F; Rachmilewitz, D1
Cadet, J; Corpet, DE; Deloly, A; Jaeg, JP; Petit, CR; Tardieu, D1
Furukawa, M; Horie, Y; Kataoka, H; Koyama, R; Nakatsugi, S1
Cho, C; Guo, X; Ko, JK; Lam, S; Liu, ES; Wong, BC; Ye, Y1
Bennett, A; Vila, D1
Jain, NK; Kulkarni, SK; Singh, A1
Jain, NK; Kulkarni, SK; Patil, CS; Singh, A; Singh, VP1
Bishnoi, M; Kulkarni, SK; Kumar, A; Patil, CS1
Candelario-Jalil, E; Fiebich, BL; García-Cabrera, M; González-Falcón, A; León, OS1
Dhir, A; Kulkarni, SK; Naidu, PS1
Chordia, MD; Huang, T; Li, F; Linden, J; Macdonald, TL; Yang, M1
Ansari, MA; Goli, D; Hussain, SK; Mudagal, MP1
Comez, M; Kurt, N; Sener, E; Suleyman, Z; Yapanoglu, T1
Batista, DDC; Costa, EA; da Silva, DM; da Silva, DPB; de Ávila, RI; Florentino, IF; Gil, ES; Leite, KCS; Lião, LM; Lino, RC; Martins, JLR; Menegatti, R; Silva, ALP; Valadares, MC; Vasconcelos, GA; Vaz, BG; Verli, H; Villavicencio, B1
Kaplan, S; Mammadov, R; Onat, T; Sunar, M; Turkler, C; Yazici, GN; Yildirim, E1

Reviews

2 review(s) available for nimesulide and mocetinostat

ArticleYear
Nimesulide as a downregulator of the activity of the neutrophil myeloperoxidase pathway. Focus on the histoprotective potential of the drug during inflammatory processes.
    Drugs, 1993, Volume: 46 Suppl 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Down-Regulation; Humans; Inflammation; Neutrophils; Oxidation-Reduction; Peroxidase; Sulfonamides

1993
[Nimesulide - a non-steroidal anti-inflammatory drug, a preferential cyclooxygenase-2 inhibitor].
    Vutreshni bolesti, 2000, Volume: 32, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Cytokines; Humans; Matrix Metalloproteinase Inhibitors; Neutrophils; Peroxidase; Prostaglandin Antagonists; Sulfonamides

2000

Other Studies

16 other study(ies) available for nimesulide and mocetinostat

ArticleYear
Inactivation of neutrophil-derived hypochlorous acid by nimesulide: a potential mechanism for the tissue protection during inflammation.
    International journal of tissue reactions, 1990, Volume: 12, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Inflammation; Male; Neutrophils; Oxygen Consumption; Peroxidase; Sulfonamides; Superoxides

1990
Inactivation of alpha-1-proteinase inhibitor by neutrophil metalloproteinases. Crucial role of the myeloperoxidase system and effects of the anti-inflammatory drug nimesulide.
    Respiration; international review of thoracic diseases, 1993, Volume: 60, Issue:1

    Topics: alpha 1-Antitrypsin; Anti-Inflammatory Agents, Non-Steroidal; Humans; In Vitro Techniques; Leukocyte Elastase; Male; Metalloendopeptidases; Neutrophils; Pancreatic Elastase; Peroxidase; Sulfonamides

1993
Cyclo-oxygenase-2 inhibitors ameliorate the severity of experimental colitis in rats.
    European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase Inhibitors; Disease Models, Animal; Eicosanoids; Indomethacin; Inflammation; Interleukin-1; Male; Nitric Oxide Synthase; Peroxidase; Pyrazoles; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sulfonamides; Tumor Necrosis Factor-alpha

2000
The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats.
    Carcinogenesis, 2000, Volume: 21, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Colitis; Cyclooxygenase Inhibitors; Deoxyguanosine; Female; Intestinal Mucosa; Oxidative Stress; Peroxidase; Rats; Rats, Inbred F344; Sulfonamides; Superoxides

2000
Interaction between NSAIDs and steroid in rat stomach: safety of nimesulide as a preferential COX-2 inhibitor in the stomach.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA; Drug Interactions; Drug Synergism; Gastric Mucosa; Gastrointestinal Motility; Indomethacin; Isoenzymes; Male; Membrane Proteins; Peroxidase; Prednisolone; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach; Stomach Ulcer; Sulfonamides

2000
Protective role of cyclooxygenase inhibitors in the adverse action of passive cigarette smoking on the initiation of experimental colitis in rats.
    European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2

    Topics: Animals; Blotting, Western; Colitis; Colon; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression Regulation, Enzymologic; Indomethacin; Inflammation; Inflammatory Bowel Diseases; Isoenzymes; Leukotriene B4; Male; Membrane Proteins; Peroxidase; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tobacco Smoke Pollution; Trinitrobenzenesulfonic Acid

2001
Role of cysteinyl leukotrienes in nociceptive and inflammatory conditions in experimental animals.
    European journal of pharmacology, 2001, Jun-29, Volume: 423, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cell Migration Inhibition; Cell Movement; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Female; Indoles; Inflammation; Leukocytes; Leukotriene Antagonists; Leukotrienes; Male; Mice; Nociceptors; Pain; Pain Measurement; Peroxidase; Phenylcarbamates; Rats; Rats, Wistar; Sulfonamides; Time Factors; Tosyl Compounds

2001
Effect of nimesulide on acetic acid- and leukotriene-induced inflammatory bowel disease in rats.
    Prostaglandins & other lipid mediators, 2003, Volume: 71, Issue:3-4

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colon; Cyclooxygenase Inhibitors; Inflammatory Bowel Diseases; Leukotriene B4; Peroxidase; Rats; Rats, Wistar; Sulfasalazine; Sulfonamides

2003
Co-administration of acetyl-11-keto-beta-boswellic acid, a specific 5-lipoxygenase inhibitor, potentiates the protective effect of COX-2 inhibitors in kainic acid-induced neurotoxicity in mice.
    Pharmacology, 2007, Volume: 79, Issue:1

    Topics: Administration, Oral; Animals; Antinematodal Agents; Brain; Catalase; Cyclooxygenase 2 Inhibitors; Drug Synergism; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Glutathione; Indomethacin; Injections, Intraperitoneal; Kainic Acid; Lactones; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred Strains; Nitric Oxide; Peroxidase; Sulfonamides; Sulfones; Triterpenes

2007
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats.
    Journal of neurochemistry, 2007, Volume: 100, Issue:4

    Topics: Animals; Blood-Brain Barrier; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Leukocytes; Male; Neurologic Examination; Peroxidase; Prostaglandins E; Rats; Rats, Sprague-Dawley; Salicylates; Statistics, Nonparametric; Sulfonamides

2007
Neuroprotective effect of nimesulide, a preferential COX-2 inhibitor, against pentylenetetrazol (PTZ)-induced chemical kindling and associated biochemical parameters in mice.
    Seizure, 2007, Volume: 16, Issue:8

    Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Epilepsy; Glutathione; Kindling, Neurologic; Lipid Peroxidation; Male; Mice; Nitrites; Pentylenetetrazole; Peroxidase; Sulfonamides; Time Factors

2007
Neutrophil- and myeloperoxidase-mediated metabolism of reduced nimesulide: evidence for bioactivation.
    Chemical research in toxicology, 2010, Nov-15, Volume: 23, Issue:11

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Humans; Hydrogen Peroxide; Hypochlorous Acid; Microsomes, Liver; Neutrophils; Oxidation-Reduction; Peroxidase; Sulfonamides; Tandem Mass Spectrometry

2010
Neuroprotective effect of allopurinol and nimesulide against cerebral ischemic reperfusion injury in diabetic rats.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:2

    Topics: Allopurinol; Animals; Brain Ischemia; Catalase; Diabetes Mellitus, Experimental; Female; Male; Neuroprotective Agents; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Streptozocin; Sulfonamides; Superoxide Dismutase

2013
The effect of nimesulide on oxidative damage inflicted by ischemia-reperfusion on the rat renal tissue.
    Renal failure, 2015, Volume: 37, Issue:2

    Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Kidney; Kidney Diseases; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reperfusion Injury; Sulfonamides; Time Factors; Treatment Outcome

2015
Pharmacological evaluation and molecular docking of new di-tert-butylphenol compound, LQFM-091, a new dual 5-LOX/COX inhibitor.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Aug-30, Volume: 106

    Topics: 3T3 Cells; Animals; Carrageenan; Cell Survival; Cyclooxygenase Inhibitors; Cytokines; Edema; Female; Hot Temperature; Hyperalgesia; Leukocyte Count; Lipoxygenase; Lipoxygenase Inhibitors; Mice; Molecular Docking Simulation; Pain Measurement; Peroxidase; Phenols; Physical Stimulation; Pleurisy; Prostaglandin-Endoperoxide Synthases; Stomach Ulcer; Sulfonamides

2017
Can the negative effects of ketamine abuse on female genital organs be prevented by nimesulide? An experimental study.
    General physiology and biophysics, 2019, Volume: 38, Issue:5

    Topics: Animals; Antioxidants; Female; Glutathione; Ketamine; Malondialdehyde; Ovary; Oxidative Stress; Peroxidase; Random Allocation; Rats; Rats, Wistar; Sulfonamides; Superoxide Dismutase; Uterus

2019